Home                              中文

Forthcoming Articles Current Issue Archive Advanced Search Read Articles Download Articles Email Alert

Quick Search     Adv Search 2021 Vol. 28, No. 21 Published: 2021-07-28   4 Dose ranging effects of Pregabalin on postoperative pain undergoing radical resection of esophageal cancer under thoracoscopy ZHOU Xiao-kai; YANG Min; CHEN Yu; GONG Chan-juan Objective To investigate the effect of different doses of Pregabalin on postoperative pain undergoing radical resection of esophageal cancer under thoracoscopy. Methods A total of 120 patients underwent radical resection of esophageal cancer under thoracoscopy in the First Affiliated Hospital of Nanjing Medical University from January 2019 to January 2020 were selected as the research objects. The patients were divided into group P1 (low-dose pregabalin,30 cases), group P2 (medium-dose pregabalin, 30 cases), group P3 (high-dose pregabalin, 30 cases) and group C (no pregabalin, 30 cases) by random number table method. Patients in group P1 received orally Pregabalin concentration of 75 mg respectively, at 8 pm a night before surgery, 1 h before surgery and 6 h after surgery. Patients in group P2 received orally Pregabalin concentration of 150 mg respectively, at 8 pm a night before surgery, 1 h before surgery and 6 h after surgery. Patients in group P3 received orally Pregabalin concentrations of 300 mg respectively, at 8 pm a night before surgery, 1 h before surgery and 6 h after surgery, whereas group C received no oral analgesic drugs at the same scheme. The visual analogue score (VAS) in resting and cough state, Ramsay score in anaestheti-induced sedation(Ramsay), and 2 h after operation in the recovery room (T0), 2 h after operation (T1), 6 h after operation (T2), 12 h after operation (T3), 24 h after operation (T4) and 48 h after operation (T5), Pittsburgh Sleep Quality Index (PSQI) score, 48 h postoperative intravenous controlled analgesia pump (PCIA) dosage, dizziness, nausea and vomiting, visual impairment,pruritus, peripheral edema and other adverse reactions were compared. Results VAS scores in T0, T1, T2, T3, T4 and T5 in groups P1, P2 and P3 were lower than those in group C in resting and coughing state, and the differences were statistically significant (P<0.05). The Ramsay score be-fore induction of group P1, P2, P3 were lower than those of group C, and the differences were statistically significant(P<0.05). The PSQI score of group P1, P2, P3 were lower than those of group C, and the differences were statistically significant (P<0.05). The dosage of analgesics in PCIA of group P1, P2, P3 were lower than those of group C, the dosage of Group P2, P3 were lower than those of Group P1, the dosage of group P3 was lower than that of group P2,and the differences were statistically significant (P<0.05). The incidence of dizziness of group P3 was lower than that of group P1, P2, C, and the differences were statistically significant (P<0.05). Conclusion The application of Pregabalin in the radical surgery of thoracoscopic esophageal cancer can alleviate the postoperative pain, and oral administration of 150 mg Pregabalin is an effective and safe method for postoperative pain management after radical resection of esophageal cancer under thoracoscopy. 2021 Vol. 28 (21): 4-8 [Abstract] ( 43 ) HTML (48 KB)  PDF  (0 KB)  ( 5 ) 9 Effect and influencing factors of intra-arterial mechanical thrombectomy in the treatment of ischemic stroke HU Shan; ZHENG Chao; HE Huan Objective To investigate the effect and influencing factors of intra - arterial mechanical thrombectomy in the treatment of ischemic stroke. Methods Clinical data of 113 patients with ischemic stroke admitted to General Hospital of Pingxiang Mining Group Co., Ltd. from January 2018 to March 2020 were retrospectively analyzed and divided into group A (53 cases) and group B (60 cases) according to treatment methods. Patients in group A were treated with intra-arterial thrombolysis, and patients in group B were treated with intra-arterial mechanical thrombectomy. Group B patients were then divided into good prognosis group (40 cases) and poor prognosis group (20 cases) according to prognosis. The hemodynamic indexes of group A and group B before and 14 days after surgery were compared. The basic clinical data of patients with good prognosis and patients with poor prognosis were compared, and the influencing factors of prognosis were analyzed. Results 14 days after surgery, the maximum peak flow velocity (VS) in group A and B was higher than that before surgery, and group B was higher than group A, while the vascular resistance index (RI) and vascular pulse index (PI) were lower than that before surgery, and group B was lower than group A, the differences were statistically significant (P<0.05). Univariate analysis showed that the proportion of males, the proportion of recanalization, and the preoperative Alberta stroke program early CT (ASPECT) score in the good prognosis group were higher than those in the poor prognosis group, and the time from admission to recanalization was shorter than that in the poor prognosis group. The proportion of posterior circulatory occlusion site, National institutes of health stroke scale (NIHSS)score 24 h after surgery and intracranial hemorrhage rate were lower than those in the poor prognosis group, the differences were statistically significant (P<0.05). Multivariate Losgistic regression analysis showed that the occlusion of the posterior circulation, the time from admission to recanalization≥140 min, the NIHSS score≥10 points at 24 h after surgery, and the occurrence of intracranial hemorrhage at 24 h after surgery were all treated by intraarterial mechanical thrombectomy for ischemic Risk factors for poor prognosis after stroke (P<0.05). Conclusion Intraarterial mechanical thrombectomy can improve the hemodynamics of patients with ischemic stroke and effectively open blood vessels. At the same time, intervention should be aimed at the risk factors of poor prognosis to improve the prognosis of patients. 2021 Vol. 28 (21): 9-12 [Abstract] ( 39 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 13 Meta-analysis of traditional Chinese herbal medicine decoction combined with lifestyle interventions in the treatment of impaired glucose regulation LI Ting-ting; ZHANG Hong;LI Wei Objective To assess curative effects and the safety of traditional Chinese herbal medicine decoction combined with lifestyle interventions for impaired glucose regulation (IGR).Methods The Chinese and English databases were searched, and the search time limit was from January 1, 2016 to August 21, 2020. Randomized controlled trials of traditional Chinese medicine compound decoction combined with lifestyle intervention in the treatment of IGR were collected. After screening, data extraction, risk of bias and quality assessment, RevMan 5.3 was used for meta-analysis.Results A total of 8 RCTs including 666 patients were included. Meta-analysis showed that fasting blood glucose(FBG) [MD=-0.68, 95%CI (-0.94, -0.43), P<0.000 01], 2 h postprandial blood glucose (2 h PBG) [MD=-0.87, 95%CI(-1.15, -0.58), P<0.000 01], glycosylated hemoglobin (HbA1c) [MD=-0.42, 95%CI (-0.62, -0.22), P<0.0001], fasting insulin (FINS) [MD=-1.85, 95%CI (-2.64, -1.06), P<0.000 01], total cholesterol (TC) [MD=-0.75, 95%CI (-1.09, -0.41), P<0.0001], triglyceride (TG) [MD=-0.78, 95%CI (-1.08, -0.48), P<0.000 01], body mass index (BMI) [MD=-1.71, 95%CI(-2.49, -0.94), P<0.0001] in experimental group were lower than control group. Only one study reported adverse reactions. Conclusion Based on the current clinical evidence, traditional Chinese herbal medicine decoction combined with lifestyle interventions for IGR might be superior in reducing the level of FBG、2 h PBG、HbA1c、FINS、TC and TG than only lifestyle interventions. However, due to the low quality of literature and publication bias, high-quality clinical researches are still needed. 2021 Vol. 28 (21): 13-18 [Abstract] ( 41 ) HTML (54 KB)  PDF  (0 KB)  ( 7 ) 19 A prospective phase Ⅱstudy of Gabapentin combined with Oxycontin in the treatment of pain in radiation oral mucositis XIA Xiao-long；ZHANG Wen-ping；HU Jian-bing； SHU yun； WANG Hong-yun； WANG Xu； ZOU Cai-liang；GAN Xiao-ling Objective To study the effect of Gabapentin combined with Oxycontin in the treatment of pain in radiation oral mucositis. Methods From May 2019 to September 2020, 58 patients with radiation oral mucositis who were treated in the Third People′s Hospital of Jiujiang City were selected as the research subjects. According to the random number table method, they were divided into control group (29 cases) and treatment group (29 cases). Patients in the control group were treated with Oxycontin, and patients in the treatment group were treated with Gabapentin combined with Oxycontin. Both groups were treated for eight weeks. The pain scores of numeric rating scale (NRS) scores of the two groups were compared before treatment and at 2, 4, 6 and 8 weeks after treatment. The proportions of grade 1-2 and grade 3-4 in oral mucosa radiation injury grading were compared between the two groups after 2 and 8 weeks of treatment. The quality of life 1 week before radiotherapy and the end day of radiotherapy and the incidence of adverse reactions during treatment were compared between the two groups. The total cost of analgesics after treatment was compared between the two groups. Results There was no statistically significant difference in NRS score of patients between the two groups before treatment (P>0.05). The NRS scores of the two groups at 2, 4, 6 and 8 weeks of treatment were lower than those before treatment, with statistically significant differences (P<0.05). The NRS scores of the two groups at 4, 6 and 8 weeks of treatment were lower than those at 2 weeks of treatment, with statistically significant differences (P<0.05). The NRS score of the two groups at 6 and 8 weeks of treatment were lower than those at 4 weeks of treatment, with statistically significant differences (P<0.05). The NRS score of the two groups at the 8 weeks of treatment was lower than that at the 6th week of treatment, the difference was statistically significant (P<0.05). The NRS scores in the treatment group were lower than those in the control group at 2, 4, 6 and 8 weeks of treatment, with statistically significant differences (P<0.05). The proportions of oral mucosal radiation injury grade 1-2 in treatment group at the 2 and 8 weeks of treatment were higher than those in control group, and the differences were statistically significant (P<0.05). The proportions of oral mucosal radiation injury grade 3-4 in the treatment group at 2 and 8 weeks of treatment were lower than those in the control group, and the differences were statistically significant (P<0.05). There was no significant difference in the European Organization for Research and Treatment of Cancer head and neck cancer quality questionnaire (EORTC QLQ-H&N35) score between the two groups one week before radiotherapy (P>0.05). The EORTC QLQ-H&N35 scores at the end of radiotherapy in the two groups were lower than those one week before radiotherapy, the differences were statistically significant (P<0.05). The EORTC QLQ-H&N35 score of the treatment group was lower than that of the control group at the end of radiotherapy, the difference was statistically significant (P<0.05). The total incidence of adverse reactions in the treatment group was lower than that in the control group, and the difference was statistically significant (P<0.05). The total cost of analgesics in the treatment group was less than that in the control group after treatment, and the difference was statistically significant (P<0.05). Conclusion Gabapentin combined with Oxycontin can effectively reduce the pain degree and oral mucosal reactions of patients with radiation oral mucositis, reduce the occurrence of adverse reactions, improve the quality of life, and reduce the economic burden of drugs. 2021 Vol. 28 (21): 19-22转28 [Abstract] ( 50 ) HTML (40 KB)  PDF  (0 KB)  ( 7 ) 23 Expression of microRNA-552 and microRNA-383 in hepatocellular carcinoma and their influence on 5-year poor prognostic outcome ZHAO Juan; LI Hui; XU Pei-yan2;ZHANG Cheng-fang;DU Li-jun;CAO Tian-sheng Objective To detect the expression of microRNA-552 (miR-552) and microRNA-383 (miR-383) in hepatocellular carcinoma (HCC) and to investigate the effect of miR-552 and miR-383 on the prognosis of HCC patients.Methods From February 2011 to February 2014, 68 patients with HCC who were hospitalized and underwent radical resection in Huadu District People′s Hospital of Guangzhou City were selected, the HCC tissue of the patients was taken as the study sample, and the adjacent normal tissue(more than 5 cm from the edge of the tumor) was taken as the control sample, the relative expression of miR-552 and miR-383 was detected by real-time fluorescent quantitative polymerase chain reaction (qRT-PCR). According to the relative expression of miR-552 and miR-383 in HCC tissues, the patients were divided into miR-552 low expression group (miR-552 relative expression <1.28, n=26), miR-552 high expression group (miR-552 relative expression >1.28, n=42), miR-383 low expression group (miR-383 relative expression <0.83, n=29) and miR-383 high expression group (miR-383 relative expression >0.83, n=39). χ2 test was used to analyze the relationship between the expression of miR-552 and miR-383 and the clinicopathological characteristics of HCC. Kaplan-Meier survival curve was used to analyze the factors influencing the prognosis of HCC, and COX regression was used to analyze the factors influencing the 5-year postoperative outcome of HCC. Results The relative expression of miR-552 in HCC tissues was higher than that in adjacent normal tissues, the difference was statistically significant (P<0.05), the relative expression of miR-383 was lower than that in adjacent normal tissues, the difference was statistically significant (P<0.05); comparison of age, gender, the proportion of liver cirrhosis between miR-552 high expression group and miR-552 low expression group, the differences were not statistically significant (P>0.05), while the proportions of high differentiation, tumor diameter ≥5 cm, lymph node metastasis, distant metastasis, TNM stage Ⅲ-Ⅳand vascular invasion in miR-552 low expression group were lower than those in miR-552 high expression group, the differences were statistically significant(P<0.05); comparison of age, gender, proportions of liver cirrhosis, distant metastasis and vascular invasion between miR-383 low expression group and miR-383 high expression group, the differences were not statistically significant (P>0.05), while the proportions of high differentiation, tumor diameter ≥5 cm, lymph node metastasis and TNM stage Ⅲ-Ⅳin miR-383 low expression group were higher than those in miR-383 high expression group, the differences were statistically significant (P<0.05);the 5-year survival rate of miR-552 low expression group was higher than that of miR-552 high expression group, the difference was statistically significant (P<0.05), and the 5-year survival rate of miR-383 low expression group was lower than that of miR-383 high expression group, the difference was statistically significant(P<0.05). The high expression of miR-552 was an independent risk factor for poor prognosis 5 years after surgery (β=0.558, HR=1.748, 95%CI=1.065-2.870, P<0.05). The high expression of miR-383 was an independent protective factor for the poor prognosis 5 years after surgery (β=-0.458, HR=0.634, 95%CI=0.467-0.861, P<0.05). Conclusion The expression of miR-552 and miR-383 in HCC is increased and decreased respectively, both of them are significantly related to 5-year survival rate of HCC patients, which may have some value in judging the prognosis of HCC patients. 2021 Vol. 28 (21): 23-28 [Abstract] ( 37 ) HTML (44 KB)  PDF  (0 KB)  ( 7 ) 29 The influences of Cinobufacin Capsules combined with XELOX regimen for neoadjuvant chemotherapy on therapeutic effects and prognosis in the treatment of locally advanced rectal cancer ZHANG Zhi-yan Objective To explore the influences of Cinobufacin Capsules combined with Capecitabine plus Oxaliplatin(XELOX) regimen for neoadjuvant chemotherapy on therapeutic effects and prognosis in the treatment of locally advanced rectal cancer. Methods A total of 72 patients with rectal cancer admitted to Songzi Hospital of Traditional Chinese Medicine from March 2013 to March 2015 were selected as the research objects, they were divided into the study group and the control group according to the random number table method, with 36 cases in each group. The control group received neoadjuvant chemotherapy with XELOX regimen, and the study group received Cinobufacin capsules combined with XELOX regimen. Three weeks as one treatment course, both groups were treated for 2 courses.The clinical efficacy, survival rate, quality of life and adverse reactions were compared between the two groups. Results The total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). The disease control rate of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). There was no significant difference in 1-year survival rate between the two groups (P>0.05); the 2-year and 3-year survival rates in the study group were higher than those in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the quality of life score between the two groups before treatment(P>0.05);the quality of life scores of the two groups at 1 and 3 months after treatment were higher than those before treatment of this group, the quality of life scores at 3 months after treatment were higher than those at 1 month after treatment in both groups, and the quality of life score of the study group was higher than that of the control group 1 and 3 months after treatment, and the differences were statistically significant(P<0.05). There was no significant difference in the adverse reactions between the two groups (P>0.05). Conclusion Cinobufacin Capsules combined with XELOX regimen for neoadjuvant chemotherapy in the treatment of locally advanced rectal cancer can significantly improve the total effective rate of clinical treatment and disease control rate, prolong the survival time of patients, improve their quality of life, at the same time, it does not increase adverse reactions. 2021 Vol. 28 (21): 29-32 [Abstract] ( 47 ) HTML (38 KB)  PDF  (0 KB)  ( 5 ) 33 Research progress on the influencing factors and protective measures of intraoperative stress injury LIANG Ye-mei; HUANG Yan; LIANG Qiu-jian; XU Song; ZHU Xia ;HUANG Ping This article through to the influence factors of intraoperative stress injury such as position, mechanical factors, reperfusion injury, personal factors, factors related to the operation of system analysis, and the nursing measures such as raising awareness and rational use of assessment, basic nursing in place, the rational use of protective equipment, strengthen the position management, strengthen the patrol, standardize the handover process and so on were reviewed. Through reading relevant literature in the past, this paper aims to summarize the effective nursing measures to prevent intraoperative stress injury, and share them with the operating room nursing peers with the help of medical literature information technology platform, so as to effectively prevent the occurrence of surgical stress injury. 2021 Vol. 28 (21): 33-36 [Abstract] ( 51 ) HTML (40 KB)  PDF  (0 KB)  ( 8 ) 37 Research progress on the application of pneumatic tourniquet in Total Knee Arthroplasty XUE Yuan; HU Xue-yu; JIN Qun-hua Osteoarthritis (OA) is the most common musculoskeletal system disease in the elderly, to degeneration of articular cartilage destruction, sclerosis of subchondral bone or cystic change, the edge of bone hyperplasia, joint synovial hyperplasia, etc. As the main pathological characteristics, is a major cause of pain and physical disability in the elderly. The knee joint as major weight-bearing joints of human body, the OA and the vast majority. There is for the treatment of the knee joint OA non-drug treatment, drug therapy and surgery, however, non-drug therapy and drug therapy can relieve pain, cannot effect a radical cure. Surgical treatment could delay the disease fundamentally, improve symptoms, correct the deformity, restore function. Total knee arthroplasty (TKA) is considered to be one of the most successful operation scheme of the last century. Since the advent of pneumatic tourniquet, it by its excellent compression hemostasis effect, provides a more clear operation visual field, performer effectively shorten the duration of the procedure, thus obtained widespread application in orthopedic surgery. 2021 Vol. 28 (21): 37-40 [Abstract] ( 46 ) HTML (41 KB)  PDF  (0 KB)  ( 9 ) 41 Observation on the curative effect of intelligent moxa steaming moxibustion combined with exercise therapy in the treatment of hemiplegic spasticity after stroke YAN Xiao-yan; YU Xue-qin; DING Hong; YUAN Ming-hua; WANG Xiao-yuan; ZOU Wen-bing Objective To investigate the effect of intelligent moxa steaming moxibustion combined with kinesitherapy on hemiplegic spasticity after stroke. Methods A total of 60 stroke patients with hemiplegic spasticity who were discharged from the Department of Rehabilitation Medicine of Yichun People′s Hospital from May 2019 to April 2020 were selected and divided into the observation group (30 cases) and the control group (30 cases) according to random number table method. Two groups of patients were given conventional oral medication to prevent recurrence of stroke.The control group was given exercise therapy, and the observation group was treated with intelligent moxa steaming moxibustion instrument on the basis of exercise therapy. The curative effect of spasticity, Fugl-Meyer assessment (FMA)score and Barthel index (BI) score of activities of daily living in the two groups were observed. Results The total effective rate of limb spasticity (upper limbs and lower limbs) in the observation group was higher than that in the control group, the difference was statistically significant (P＜0.05). There was no significant difference in the FMA score and BI score between the two groups before intervention (P＞0.05). The FMA score and BI score of the two group after intervention were higher than those before intervention, the differences were statistically significant (P＜0.05). The FMA score and BI score of the observation group after intervention were higher than those of the control group, the differences were statistically significant (P＜0.05). Conclusion Intelligent moxa steaming moxibustion combined with exercise therapy has a good effect in the treatment of hemiplegic spasticity after stroke. It can improve the spasticity of limbs (upper limbs and lower limbs), and improve the FMA score and BI score of patients, which has higher application value. 2021 Vol. 28 (21): 41-44 [Abstract] ( 46 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 45 Timing of operation and its influence on prognosis of cholecystolithiasis complicated with mild to moderate pancreatitis MING Zhi-xiang;XU Jian-hua;ZHANG Ruo-yi Objective To explore the influence on prognosis of different operation time on cholecystolithiasis complicated with mild to moderate pancreatitis. Methods A total of 60 patients with cholecystolithiasis complicated with mild to moderate pancreatitis admitted to Nantong Hospital of Traditional Chinese Medicine from January 2017 to August 2020 were selected as the research objects, and divided into the control group and the observation group according to the random number table method, with 30 cases in each group. The control group received surgical treatment from 72 hours to 14 days after onset, and the observation group received surgical treatment within 72 hours. The serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), amylase (AMY), surgical indicators (including the operation time, interoperative bleeding volume, postoperative feeding time and postoperative hospitalization time), total complication rate and quality of life score (including the MOS item short from health survey[SF-36] and visual analog scale [VAS] scores). Results After the surgery, the levels of AST, ALT, ALP and AMY in two groups were lower than those in this group before the surgery, and the levels of AST, ALT, ALP and AMY in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05).There were no significant differences in the operation time, interoperative bleeding volume, postoperative feeding time between the two groups (P>0.05); and the postoperative hospitalization time of the observation group was shorter than that of the control group, the difference was statistically significant (P<0.05). The total complication rate of the observed group was lower than that of the control group,the difference was statistically significant (P<0.05). After the surgery, the SF-36 score of the two groups were higher than those of this group before the surgery, and the SF-36 score of the observation group was higher than that of the control group, the differences were statistically significant (P<0.05). After the surgery, the VAS score of the two groups were lower than those of this group before the surgery, and the VAS score of the observation group was lower than that of the control group, the differences were statistically significant(P<0.05). Conclusion The clinial effect of patients with gallstone complicated with mild to moderate pancreatitis were received surgical treatment within 72 hours is better, and the effect is good. It could effectively shorten the time of hospitalization, reduce infection, reduce the occurrence of complications, and could be used in clinical practice. 2021 Vol. 28 (21): 45-48 [Abstract] ( 46 ) HTML (37 KB)  PDF  (0 KB)  ( 8 ) 49 Influence of mobile ICU transfer mode on the treatment and transportation of critical patients in our city SONG Xiao-li ;LIAO Qiu-mei;FU Qun-xiu Objective To explore the influience of mobile ICU transport mode on the treatment and transportation of critical patients in Xinyu city. Methods From January 2019 to October 2020, 76 patients in Department of Emergency of Emergency Rescue Center of Xinyu City in Jiangxi Province were selected as the research objects, and they were divided into the control group (38 cases) and the observation group (38 cases) according to different transport modes. The control group was transported by ordinary ICU, mobile ICU transfer mode was used in the observation group. The safe transport and the incidence of adverse events were compared between the two groups. Results The rate of safe transport in the observation group was higher than that in the control group, the difference was statistically significant (P＜0.05).The total incidence rate of adverse events in the observation group was lower than that in the control group, the difference was statistically significant (P＜0.05). Conclusion During the treatment and transportation of critically ill patients in our city, the mobile ICU transfer mode can improve the safe transport effect and reduce the incidence of adverse events. It can improve the safety of patients with serious diseases and is worth promoting. 2021 Vol. 28 (21): 49-51 [Abstract] ( 38 ) HTML (30 KB)  PDF  (0 KB)  ( 6 ) 52 Application of SOFIA PLUS distal access catheter extraction plug and SOLITAIRE stent system stent plug in acute intracranial arterial occlusion NI Fu-wen；LI Cheng-ying；CHEN Shui-hong； HUANG Jin-bo Objective To explore the application of SOFIA PLUS distal access catheter extraction plug and SOLITAIRE stent system stent plug in acute intracranial arterial occlusion. Methods A total of 60 patients with acute intracranial arterial occlusive ischemic stroke admitted to People′s Hospital of Dianbai District and People′s Hospital of Maoming City from February 2019 to September 2019 were selected as the research objects. According to random number table method, they were divided into the control group and the observation group, with 30 cases in each group. Patients in the control group were treated with SOLITAIRE stent embolectomy, and patients in the observation group were treated with SOFIA PLUS distal access catheter aspiration. The immediate effect of thrombectomy and the interim effect were compared between the two groups. Results There were no statistically significant differences in the National Institute of Health stroke scale (NIHSS) score 24 hours after surgery, vascular recanalization rate, perioperative mortality and incidence of postoperative complications between the two groups (P>0.05).The average recanalization time of the observation group was shorter than that of the control group, and the difference was statistically significant (P<0.05). There were no statistically significant differences between the two groups in NIHSS score 14 d after surgery, number of cases ≤2 in modified Rankin scale (mRs) score 3 months after surgery and survival rate 3 months after surgery (P>0.05). Conclusion The two treatments had similar postoperative effect, but the SOFIA PLUS catheter extraction and thrombolysis therapy had shorter recanalization time than SOLITAIRE stent system. 2021 Vol. 28 (21): 52-54转58 [Abstract] ( 34 ) HTML (32 KB)  PDF  (0 KB)  ( 8 ) 55 Effect of drugs combined with cognitive behavior therapy for recurrent depressive disorder SU Jin-ge；JIANG Hai-jun；LIU Xiao-mei Objective To observe the effect of drugs combined with cognitive behavior therapy for recurrent depressive disorder. Methods From June 2019 to September 2020, 100 patients with recurrent depressive disorder in Huizhou Second People′s Hospital and Huizhou Demobilized Veterans Hospital were selected, and they were divided into two groups according to the admission time, 50 cases in each group. The control group was given drug treatment, and the study group was given drug combined with cognitive behavior therapy. The Hamilton depression scale (HAMD), selfrating depression scale (SDS) and the MOS item short from health survey (SF-36) scores before and after treatment and incidence of adverse reactions were compared and analyzed between the two groups. Results There was no significant difference in HAMD score between the two groups before treatment (P>0.05). At 4 and 8 weeks of treatment, the HAMD scores of the two groups were lower than those before treatment, and those in the study group were lower than those in the control group, the differences were statistically significant (P<0.05). There was no significant difference in SDS score between the two groups before treatment (P>0.05). At 4 and 8 weeks of treatment, the SDS scores of the two groups were lower than those before treatment, and those in the study group were lower than those in the control group,the differences were statistically significant (P<0.05). There was no significant difference in SF-36 score between the two groups before treatment (P>0.05). At 4 and 8 weeks of treatment, the SF-36 scores of the two groups were higher than those before treatment, and those in the study group were higher than those in the control group, the differences were statistically significant (P<0.05). There was no significant difference in the total incidence of adverse reactions such as headache, constipation, nausea, tachycardia, dry mouth, drowsiness, increase in appetite, and weight gain between the two groups (P>0.05). Conclusion For patients with recurrent depressive disorder, drugs combined with cognitive behavioral therapy can effectively improve clinical symptoms, with high security, and the clinical value is remarkable. 2021 Vol. 28 (21): 55-58 [Abstract] ( 45 ) HTML (36 KB)  PDF  (0 KB)  ( 8 ) 59 Changes and clinical significance of serum high mobility group protein B1 and inflammatory cytokines in patients with acute exacerbation of chronic obstructive pulmonary disease FENG Yu-jia；PI Xiu-jie；GAO Wei-wei；FU Chang-you； XU Zhi-jing Objective To investigate the changes and clinical significance of serum high mobility group protein B1 and inflammatory cytokines in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods A total of 200 COPD patients admitted to The First Affiliated Hospital of Qiqihar Medical University from February 2018 to February 2020 were selected as the research objects, and were divided into COPD stable stage group (90 cases)and COPD acute exacerbation group (110 cases) according to their disease characteristics. At the same time, 100 healthy subjects were selected as the control group. The forced expiratory volume in the first second/forced vital capacity (FEV1/FVC), the percentage of FEV1 in the predicted value (FEV1%), the serum levels of high mobility group protein B1 (HMGB1), C-reactive protein (CRP), interleukin-6 (IL-6) and interleukin-18 (IL-18) in three groups were observed. The correlation between FEV1/FVC, FEV1% and HMGB1, CRP, IL-6 and IL-18 in patients with acute exacerbation of COPD was analyzed. Results The FEV1/FVC and FEV1% in COPD acute exacerbation group were lower than those in the control group and COPD stable stage group, and the HMGB1, CRP, IL-6 and IL-18 were higher than those in the control group and COPD stable stage group, FEV1/FVC and FEV1% in COPD stable stage group were lower than those in control group, and HMGB1, CRP, IL-6 and IL-18 were higher than those in control group, the differences were statistically significant (P<0.05). In patients with acute exacerbation of COPD, FEV1/FVC and FEV1% were negatively correlated with HMGB1 and CRP, while positively correlated with IL-6 and IL-18 (P<0.05). Conclusion The levels of HMGB1, CRP, IL-6 and IL-18 are abnormally changed in COPD patients, which are related to the lung function of the patients. 2021 Vol. 28 (21): 59-61转65 [Abstract] ( 43 ) HTML (36 KB)  PDF  (0 KB)  ( 5 ) 62 Effects of comprehensive rehabilitation skills training on medication compliance and disease burden in patients with schizophrenia DENG Rong； YANG Wei-hong Objective To investigate the effects of comprehensive rehabilitation skills training on medication compliance and disease burden in patients with schizophrenia. Methods A total of 60 schizophrenic patients who were admitted to Ba′nan District Mental Health Center of Chongqing from June 2019 to March 2020 were selected as the research subjects. According to the random number table method, they divided into the study group (30 patients) and the control group (30 patients). Patients in the study group were treated with comprehensive rehabilitation skill training intervention, and patients in the control group were treated with routine health education and guidance services for schizophrenia. The intervention was conducted for 2 hours twice a week for 6 months. Before intervention and 6 months after intervention, the medication compliance scale and family burden of disease scale were used to evaluate and compare medication compliance and family burden of disease between the two groups. Results There were no significant differences were observed in the scores of the medication compliance and the family burden of disease between the two groups before intervention (P>0.05). After the intervention, the drug compliance score of the study groups was higher than that before intervention in this group, and the drug compliance score of the study group was higher than that of the control group, with the statistically significant difference (P<0.05). After the intervention, the family burden of disease score of the study group was lower than that of the control group, and the family burden of disease score of the study groups was lower than that before intervention in this group, with the statistically significant difference (P<0.05). Conclusion Compared with health education, comprehensive rehabilitation skill training can improve the medication compliance of patients with schizophrenia and reduce the family burden of disease. 2021 Vol. 28 (21): 62-65 [Abstract] ( 42 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 66 Effect observation of Jiuwei Zhenxin Granules combined with Trazodone in the treatment of anxiety with syndrome of deficiency of heart and spleen LYU Guan-jian； WANG Xiao Objective To investigate the clinical effect of Jiuwei Zhenxin Granules combined with Trazodone in the treatment of anxiety with syndrome of deficiency of heart and spleen. Methods A total of anxiety 80 patients with syndrome of deficiency of heart and spleen admitted to Northern District General Hospital of PLA from January 2018 to January 2019 were selected as the research objects. According to the random number table method, they were divided into control group (40 cases) and study group (40 cases). The control group was treated with Trazodone, and the study group was treated with Jiuwei Zhenxin Granules combined with Trazodone. The treatment effect, anxiety score and sleep disorder score before treatment, after 2 and 4 weeks of treatment, and the total incidence of adverse reactions were compared between the two groups. Results The total effective rate of the treatment in the study group was higher than that in the control group, the difference was statistically significant (P<0.05). Before treatment, the anxiety score and sleep disorder score of the two groups showed no statistically significant differences between the two groups (P>0.05).After 2 and 4 weeks of treatment, the Hamilton anxiety scale and Pittsburgh sleep index scores of the study group were lower than those of the control group, the differences were statistically significant (P<0.05). The total incidence of adverse reactions in the study group was lower than that in the control group, the difference was statistically significant(P<0.05). Conclusion Jiuwei Zhenxin Granules combined with Trazodone can improve the total effective rate, reduce the anxiety, sleep disorder scores and the incidence of adverse reactions in the treatment of anxiety patients with syndrome of deficiency of heart and spleen, with significant value. 2021 Vol. 28 (21): 66-68 [Abstract] ( 68 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 69 Application of "triple analgesia" and intelligent management in postoperative analgesia of anorectal disease QIAN Kun； WU Lie； TIAN Zhen-wu； DING Jin-huo； LUO Gang Objective To explore the application effect of "triple analgesia" and intelligent management in postoperative analgesia of anorectal disease. Methods A total of 92 patients with anorectal disease who underwent surgical treatment at Shangrao People′s Hospital from January 2019 to June 2020 were selected as the research objects, randomly numbered from 1 to 92, the odd numbers were classified as the control group, and the even numbers were classified as the observation group, with 46 cases in each group. The control group was used intelligent management intervention,and the observation group was used intelligent management combined with "triple analgesia" intervention. Both groups were intervened until 15 days after operation, and the visual analogue scale (VAS) scores, wound healing time and total incidence rates of adverse reactions at different time points after operation were vomared between the two groups. Results The differences in time, inter-group, and interaction between the two groups of patients were statistically significant (P<0.05); further pairwise comparison, intra-group comparison: the Vas score on the 1, 3, 5, 7, 10, and 15 days after surgery were all higher than 6 hours after surgery, the differences were statistically significant (P<0.05); comparison between groups: the VAS scores of the observation group at 1, 3, 5, 7, 10, and 15 days after surgery were lower than those of the control group, the differences were statistically significant (P<0.05); the wound healing time of the observation group was shorter than that of the control group, and the difference was statistically significant (P<0.05).There was no statistically significant difference in the total incidence rate of adverse reactions between the two groups(P>0.05). Conclusion "Triple analgesia" combined with intelligent management applied in postoperative analgesia of anorectal disease can effectively reduce the pain of patients, accelerate wound healing, and will not increase adverse reactions. 2021 Vol. 28 (21): 69-71转79 [Abstract] ( 42 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 72 Application of the accelerated rehabilitation surgery concept in emergency repair of upper gastrointestinal perforation in elderly patients WU Qian-long； LONG Zhi-xiang； ZHU Gong-yuan Objective To investigate the effect of the accelerated rehabilitation surgery concept in the emergency repair of upper gastrointestinal perforation in elderly patients and its influence on the incidence of complications. Methods From July 2018 to July 2020, 60 elderly patients with emergency upper gastrointestinal perforation admitted to Heyuan People′s Hospital were selected as the research objects and divided into the study group and the control group according to random number table method, with 30 cases in each group. The control group was given routine perioperative management, while the study group was given accelerated rehabilitation surgery. The treatment and hospitalization (related index time, incidence of complications and hospital satisfaction) of the two groups were compared. Results The ambulation time, exhaust time, intake time, defecation time and hospitalization time of the study group were shorter than those of the control group, and the differences were statistically significant (P<0.05). There were no statistically significant differences in total incidence of postoperative complications of the two groups (P>0.05). The total hospitalization satisfaction of the study group was higher than that of the control group, and the difference was statistically significant(P<0.05). Conclusion The concept of accelerated rehabilitation surgery can be safely used in the perioperative management of elderly patients with emergency upper gastrointestinal perforation, promote the rapid recovery of patients, shorten the length of hospital stay, and do not increase the risk of complications, effectively improve patient satisfaction. 2021 Vol. 28 (21): 72-74转83 [Abstract] ( 42 ) HTML (30 KB)  PDF  (0 KB)  ( 7 ) 75 Application effect of intraoperative nasobiliary duct replacing traditional T tube in laparoscopic cholecystectomy and choledochotomy with primary suture ZHAO Zhi-xin； CHEN Geng-zhen； XU Rui-rui Objective To investigate the application value and clinical effect of intraoperative nasobiliary duct in replacing traditional T tube in laparoscopic cholecystectomy (LC) + choledochotomy with primary suture. Methods A total of 60 patients with choledocholithiasis simultaneously with cholecystolithiasis who were admitted to the Second Affiliated Hospital of Shantou University Medical College from January 2018 to December 2019 were selected as the research subjects, and were divided into the study group and the control group according to the random number table method, with 30 patients in each group. In the study group, LC + laparoscopic common bile duct exploration (LCBDE)+ endoscopic nasobiliary drainage (ENBD) were performed, while in the control group, LC + LCBDE + T tube drainage was performed. The intraoperative and postoperative conditions of the two groups were compared. Results All 60 cases were operated successfully. No significant differences were observed in operative durations, intraoperative blood losses,drainage volumes and postoperative gastrointestinal function recovery times between the two groups (P>0.05). The drainage tube extraction time and postoperative length of hospital stay in the study group were shorter than those in the control group, and the hospitalization cost in the study group was less than that in the control group, and the differences were statistically significant (P<0.05). All patients were followed up for 6 to 10 months, and reexamination showed that:no biliary tract stenosis occurred in the two groups, and no statistically significant difference was observed in the incidences of postoperative pancreatitis between the two groups (P>0.05). The increased rate of amylase in blood and urine and the abnormal rate of liver function in the study group were lower than those in the control group, with statistically significant differences (P<0.05). Conclusion Nasobiliary duct can replace T tube drainage in LC+LCBDE, which can guarantee the safety of primary suture of choledochotomy, and its efficacy is more accurate and feasible. 2021 Vol. 28 (21): 75-79 [Abstract] ( 45 ) HTML (39 KB)  PDF  (0 KB)  ( 7 ) 80 Influence on the effect and safety of single port laparoscopic appendectomy with different treatment methods of appendix stump ZHANG Ming； ZENG Jiu-ping； YU Xiao-qiang Objective To explore the influence on the effect and safety of single port laparoscopic appendectomy with different treatment methods of appendix stump. Methods A total of 66 patients with single port laparoscopic appendectomy admitted to the First Department of Surgery of Ruijin People′s Hospital from January 2019 to November 2020 were selected as the research subjects. They were divided into observation group (n=33) and control group (n=33) by random touch ball method. Patients in the control group were treated with biological clip ligation and patients in the observation group were treated with purse bag suture. The length of stay, postoperative ventilation time, operative time,intraoperative blood loss, postoperative pain score at 8 h and the incidence of complications were compared between the two groups. Results The duration of hospital stay and postoperative ventilation in the observation group were shorter than those in the control group, and the operation time was longer than that in the control group, the differences were statistically significant (P<0.05). There were no significant differences in intraoperative blood loss and postoperative pain score at 8 h between the two groups (P>0.05). The total incidence rate of complications in observation group(3.03%) was lower than that in control group (18.18%), and the difference was statistically significant (P<0.05). Conclusion The treatment of appendix stump with biological clip ligation and purse string suture has obvious effect. Purse string suture has the advantages of rapid recovery, fewer complications and long operation time, so the reasonable treatment method can be chosen according to the situation of patients. 2021 Vol. 28 (21): 80-83 [Abstract] ( 41 ) HTML (32 KB)  PDF  (0 KB)  ( 8 ) 84 Application comparison of different approaches in left extrahepatic lobectomy WU Zhao-ping； JIN Yu-dong； PENG Lang； XIONG Ri-hui ；HU Qiu-ling Objective To compare the effect of different approaches in left extrahepatic lobectomy. Methods A total of 82 patients who needed to undergo left extrahepatic lobotomy in the First People′s Hospital of Jiujiang City from March 2017 to April 2020 were selected as the research subjects. According to random number table method, they were divided into group A and group B, with 41 cases in each group. Group A used the first hepatic portal approach, and group B used the transhepatic round ligament approach. The operation-related indexes, traumatic stress index before and 1 d after operation, liver function (alanine aminotransferase [ALT], aspartate aminotransferase [AST], hepatocyte growth factor [HGF]) before and 3 months after operation were compared between the two groups. Results There was no statistically significant difference in operation time between the two groups (P>0.05). The intraoperative blood loss in group B was lower than that in group A, and the difference was statistically significant (P<0.05). 1 day after surgery, the levels of adrenaline, interleukin-6 (IL-6), cortisol (Cor) and procalcitonin (PCT) in the groups were higher than those before surgery, and the levels of adrenaline, IL-6, Cor and PCT in group B were lower than those in group A, and the differences were statistically significant (P<0.05). 3 months after surgery, the levels of ALT, AST and TBil in the groups were lower than those before surgery, while the levels of HGF and ALB were higher than thise before surgery, and the level of HGF in group B was higher than that in group A, and the differences were statistically significant (P<0.05). 3 months after operation, there were no statistically significant differences in ALT, AST, TBil and ALB levels between the two groups (P>0.05). Conclusion Compared with the first hepatic portal approach, the transhepatic round ligament fissure approach can reduce the amount of intraoperative blood loss in patients undergoing left extrahepatic lobectomy and promote the recovery of liver function. 2021 Vol. 28 (21): 84-87 [Abstract] ( 45 ) HTML (32 KB)  PDF  (0 KB)  ( 9 ) 88 Clinical effect of thoracoscopic surgery in the treatment of spontaneous pneumothorax LIU Ke-xin Objective To explore the clinical effect of thoracoscopic surgery in the treatment of spontaneous pneumothorax. Methods A total of 50 patients with spontaneous pneumothorax admitted to Iron Coal General Hospital of Liaoning Health Industry Group from January 2019 to January 2020 were selected as the research objects and divided into the control group (25 cases) and the experimental group (25 cases) according to the random number table method.The control group was treated with conventional thoracotomy, while the experimental group was treated with thoracidoscopic surgery. And the clinical effect, intraoperative indicators, disease indicators and visual analogue scale (VAS)scores of the two groups were compared. Results The total effective rate of the experimental group was higher than that of the control group, with statistically difference (P<0.05). The operation time, drainage retention time and hospitalization time of the experimental group were shorter than those of the control group, and the intraoperative blood loss of the experimental group were less than those of the control group, the differences were statistically significant (P<0.05). Before the surgery, there were no statistically significant differences in quality of life, mental status, disease improvement,and treatment compliance scores between the two groups (P>0.05). After the surgery, the quality of life, mental status,disease improvement, and treatment compliance scores of the two groups were higher than before in this group, and the quality of life, mental status, disease improvement, and treatment compliance scores of the experimental group were higher than those of the control group, the differences were statistically significant (P<0.05). The VAS scores at 12, 24,36 and 48 hours after operation in the experimental group were lower than those in the control group, the differences were statistically significant (P<0.05). Conclusion Thoracoscopic surgery used in the clinical treatment of spontaneous pneumothorax could achieve certain clinical results. It is worth the application and promotion. 2021 Vol. 28 (21): 88-90 [Abstract] ( 37 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 91 Simultaneous fistula excision combined with loose thread operation in the treatment of complex anal fistula with perianal abscess LI Ming-yong; XIE Peng; HUANG Cai-mei;DENG Guo-jun Objective To explore the effect of concurrent fistula external resection combined with loose thread operation in the treatment of complex anal fistula complicated with perianal abscess. Methods A total of 90 patients with complex anal fistulas and perianal abscesses admitted to the First People′s Hospital of Nankang from February 2018 to February 2020 were selected as the research objects, and were divided into a control group (45 cases)and an experimental group (45 cases)according to the odd and even number method.The control group was treated with staging fistula external resection combined with loose thread surgery, while the experimental group was treated with fistula external resection combined with loose thread surgery. The clinical operative indicators, postoperative complications and treatment effects of the two groups were compared. Results The wound healing time, operation time and hospitalization time of the experimental group were shorter than those of the control group, the differences were statistically significant (P<0.05). There was no significant difference in the incidence of complications between the two groups (P>0.05). There was no statistically significant difference in the clinical total effective rate between the two groups (P>0.05). Conclusion Simultaneous and staged fistula external resection combined with loose thread surgery has better results and higher safety in the treatment of complex anal fistulas with perianal abscesses. However, the concurrent surgical plan takes shorter time, faster postoperative recovery, which can be further promoted and applied in clinical practice. 2021 Vol. 28 (21): 91-93 [Abstract] ( 43 ) HTML (31 KB)  PDF  (0 KB)  ( 8 ) 94 Clinical effect and adverse events of partial gastrectomy combined with highly selective vagus nerve resection in treatment of early gastric cancer AN Jun Objective To investigate the clinical effect and adverse events of partial gastrectomy in the treatment of early gastric cancer.Methods A total of 80 patients with early gastric cancer admitted to Haicheng Central Hospital from January 2019 to January 2020 were selected as the research objects. They were divided into the control group (40 patients) and the experimental group (40 patients) according to the random number table method. The control group were treated with radical surgery, and the experimental group were treated with partial gastrectomy combined with highly selective vagus nerve resection. The effect of surgery on the clinical effect of early gastric cancer and incidence of adverse events after surgery were compared between the two groups. Results The gastric emptying functions of the experimental group at 15, 30 and 45 min after surgery were higher than those of the control group, with statistically significant differences (P<0.05). The gallbladder contraction function of the experimental group at 45 min after surgery was lower than that of the control group, with statistically significant difference (P<0.05). The total incidence of adverse events in the experimental group was lower than that in the control group, with statistically significant difference (P<0.05). Conclusion Digestive system diseases affect the quality of life of patients. Partial gastrectomy combined with highly selective vagus resection can preserve the anatomical structure of patients in a certain sense and improve the prognostic quality of life of patients. It should be promoted in clinical practice. 2021 Vol. 28 (21): 94-96 [Abstract] ( 39 ) HTML (29 KB)  PDF  (0 KB)  ( 9 ) 97 Study on the effect and safety of using different fractional dose in accelerated hyperfractionated radiotherapy for localized small cell lung cancer LI Zhuo-hua；SHEN Gang； LIN Yu-chao Objective To observe the effect and safety of using different fractional dose in accelerated hyperfractionated radiotherapy for localized small cell lung cancer. Methods A retrospective collection of 30 patients with localized small cell lung cancer admitted to the Department of Thoracic Surgery, Guangdong Agricultural Reclamation Center Hospital from January 2018 to December 2019 was conducted for research. All patients received conventional chemotherapy combined with accelerated hyperfractionated radiotherapy, and they were divided into two groups according to the fractional dose. The total dose of the control group (15 cases) was 45 Gy, and the total dose of the observation group (15 cases) was 60 Gy. The efficacy, incidence of adverse reactions, and quality of life of the two groups were observed and compared. Results The effective rate of treatment in the observation group (80.00%) was higher than that in the control group (60.00%), and the difference was statistically significant (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups during the treatment period (P>0.05). At one month of follow-up, the total quality of life score in the observation group ([80.22±3.46] points) was higher than that in the control group ([60.81±3.67] points), the difference was statistically significant (P<0.05). Conclusion Localized small cell lung cancer by accelerated hyperfractionated radiotherapy, appropriately increasing the fractional dose has no significant increase in adverse reactions. It has higher safety and more significant curative effect, which can effectively improve the quality of life of patients. 2021 Vol. 28 (21): 97-99转103 [Abstract] ( 41 ) HTML (33 KB)  PDF  (0 KB)  ( 9 ) 100 Influence factors of insufficient physical recovery in breast cancer patients during rehabilitation QIN Ao-xiang Objective To study the influence factors of insufficient physical recovery in breast cancer patients during rehabilitation. Methods From January 2016 to December 2018, 116 patients who received regular follow-up after breast cancer surgery in Songzi Hospital of Traditional Chinese Medicine in Jingzhou City, Hubei Province were selected as the research objects. All patients were assessed by international physical activity questionnaire short form (IPAQ-SF).According to the results, all patients were divided into insufficient group (26 cases) and good group (90 cases). The clinical characteristics of the two groups were compared, and multivariate analysis was performed. Results There were 26 cases (22.41%) of patients with insufficient physical activity, 63 cases (54.31%) were moderate, and 27 cases(23.28%) were active. There were statistically significant differences in the three types of patients in sitting time, activity time, overall physical activity consumption, and medium-to-high intensity activity days (P<0.05). Univariate analysis showed that there were statistically significant differences in the proportion of patients with age≥50 years old, body mass index (BMI)≥24 kg/m2, TNM stage Ⅲ-Ⅳ, chemotherapy, cancer-related fatigue and ipsilateral lymph node edema between the two groups (P<0.05). Multivariate analysis showed that age≥50 years (β=1.915, OR=6.789, 95%CI=1.131-40.752), BMI≥24 kg/m2(β=2.420, OR=11.246, 95%CI=1.889-66.952), TNM stage Ⅲ-Ⅳ(β=2.504, OR=12.234,95%CI=2.379-62.913), chemotherapy (β=1.736, OR=5.674, 95%CI=1.324-24.316), cancer-related fatigue (β=1.812,OR=6.124, 95%CI=1.254-29.907), lymph node edema on the affected side (β=2.676, OR=14.521, 95%CI=2.346-89.880) were risk factors for insufficient physical recovery in convalescence of breast cancer patients (P<0.05).Conclusion Age,BMI,TNM stage,chemotherapy, cancer-related fatigue, and lymphedema on the affected side can all affect the physical recovery of breast cancer patients. 2021 Vol. 28 (21): 100-103 [Abstract] ( 38 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 104 Application value of image-based preliminary artificial intelligence detection in the diagnosis and treatment of neonatal jaundice HU An-hui ；ZONG Yu-min ；HU Xiao-hua； LUO Yong； FU Si-yong Objective To explore the application value of image-based preliminary artificial intelligence detection in the diagnosis and treatment of neonatal jaundice. Methods The clinical data of 200 neonates with jaundice in Maternity& Child Care Center of Xinyu from October 2018 to December 2019 were retrospectively analyzed. According to the types of jaundice, the neonates were divided into physiological jaundice group (n=102) and pathological jaundice group(n=98). Diag analysis detection system was used to collect relevant data of the two groups of children patients. The neonatal transcutaneous bilirubin (TcB), automated image-based bilirubin (AIB) and new artificial intelligence bilirubin(DiagB) were compared between the two groups. Receiver operating characteristics (ROC) curve was used to describe the diagnostic efficacy of the above quantitative parameters on neonatal pathological jaundice. The accuracy of DiagB in the diagnosis of neonatal jaundice was calculated by using total serum bilirubin (TSB) as the gold standards for the diagnosis of neonatal jaundice. Results The detection values of TcB, AIB and DiagB in pathological jaundice group were higher than those in physiological jaundice group, the differences were statistically significant (P<0.05). The area under ROC curves (AUC) of TcB, AIB and DiagB in the diagnosis of pathological jaundice were 0.774, 0.764 and 0.792, and the cut-off values were 228.59 μmol/L, 213.13 μmol/L and 214.96 μmol/L respectively. The sensitivity,specificity, accuracy rate, positive predictive value, negative predictive value and Kappa value of DiagB in the diagnosis of neonatal pathological jaundice were 74.49% (73/98), 77.45% (79/102), 76.00% (152/200), 76.04% (73/96), 75.96%(79/104) and 0.520. Conclusion Image-based DiagB value detection has high efficacy in diagnosing neonatal pathological jaundice, and it is highly consistent with serum TSB and biochemical test results. Thus it can provide a new safe and non-invasive monitoring method for neonatal pathological jaundice. 2021 Vol. 28 (21): 104-107 [Abstract] ( 37 ) HTML (34 KB)  PDF  (0 KB)  ( 9 ) 108 Application value of clinical common blood biochemical index changes in perinatal period of elderly pregnant women GUO Ling-li Objective To explore the application value of clinical common blood biochemical index changes in perinatal period of elderly pregnant women. Methods A total of 30 cases of elderly pregnant women in Ruijin Maternal and Child Health Hospital from January 2018 to December 2019 were selected as the research group, and 30 cases of age appropriate pregnant women in the same period were selected as the control group. The serum total cholesterol (TC) and total bile acid (TBA) in early pregnancy (gestational age ≤12 weeks), mid pregnancy (gestational age 20-25 weeks),late pregnancy (gestational age 38-42 weeks) and postpartum 3 days were compared between the two groups）. High density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG), triglyceride (TG), activated partial thromboplastin time (APTT), D-Dimer (D-D), prothrombin time (PT), fibrinogen (FIB), fibrinogen degradation products (FDP), adverse pregnancy events. Results There were no significant differences in D-D and FIB between the two groups in each period(P>0.05). TBA in the early pregnancy study group was lower than that in the control group, while HDL-C, FBG and PT were higher than those in the control group (P<0.05). TC, HDL-C, FBG, APTT and PT in the middle and late pregnancy study group were higher than those in the control group (P<0.05). TC and HDL-C in the postpartum three days in the study group were higher than those in the control group (P<0.05), FBG, TG were higher than those in the control group,FDP was lower than that in the control group, the differences were statistically significant (P<0.05); the total incidence of adverse pregnancy events in the study group was higher than that in the control group, the difference was statistically significant (P<0.05). Conclusion The risk of dyslipidemia and coagulation dysfunction of elderly pregnant women is higher than that of the right age pregnant women. The clinic can improve the prevention and control level of complications by strengthening the detection of common blood biochemical indexes such as blood lipid level and coagulation function of elderly pregnant women in each period of pregnancy. 2021 Vol. 28 (21): 108-111 [Abstract] ( 42 ) HTML (30 KB)  PDF  (0 KB)  ( 7 ) 112 Clinical effect of immunoglobulin in the treatment of sepsis in children and influence on immune function WU Si-xian； HE Dao-ji ；YE Yong-zhi； HE Hai-yan Objective To investigate the clinical effect of immunoglobulin in the treatment of children with sepsis and its effect on immune function. Methods A total of 40 children with sepsis treated in the Department of Pediatrics of Zhaoqing First People′s Hospital from May 2019 to April 2020 were selected as the research objects, and divided into control group (20 cases) and intervention group (20 cases) according to random drawing method. The control group received conventional symptomatic treatment, and the intervention group received additional immunoglobulin treatment on the basis of the control group. The therapeutic effect and the levels of immunoglobulin (IgG, IgA, IgM) and complement(C3, C4) before and after treatment were compared between the two groups. Results The total effective rate of the intervention group was 90.00%, which was higher than that of the control group, the difference was statistically significant(P<0.05). There was no significant difference in the levels of IgG, IgA and IgM between the two groups before treatment(P>0.05). After treatment, IgG levels in the intervention group were higher than before treatment and higher than those in the control group, the differences were statistically significant (P<0.05). There was no significant difference in IgA and IgM levels between the two groups after treatment (P>0.05). Before treatment, there was no significant difference in C3 and C4 levels between the two groups (P>0.05). After treatment, the levels of C3 and C4 in the two groups were lower than before treatment, and the levels of C3 and C4 in the intervention group were lower than those in the control group, the differences were statistically significant (P<0.05). Conclusion Immunoglobulin in the treatment of sepsis in children has significant clinical effect, can effectively improve the immune function and clinical symptoms of children,promote the recovery, it is worthy of popularization and application. 2021 Vol. 28 (21): 112-114 [Abstract] ( 38 ) HTML (29 KB)  PDF  (0 KB)  ( 10 ) 115 Analysis of the influencing factors of residual recurrence after hysteromyomectomy SHI Xing-hua； HUANG Hai-yan；ZHANG Shuai-sai Objective The influencing factors of residual recurrence after hysteromyomectomy were analyzed to provide the basis for the prevention and treatment of residual recurrence after hysteromyomectomy. Methods The clinical data of 68 patients who underwent hysteromyomectomy in the Nantong Maternal and Child Health Care Hospital and Qidong Maternal and Child Health Care Hospital from February 2017 to March 2020 were retrospectively analyzed. Residual recurrence of all patients within 6 months after surgery was counted. Clinical data of patients were collected, including age, surgical method, number of fibroids, fibroid diameter, fibroid location, fibroid type, serum prolactin (PRL) and matrix metalloproteinase-9 (MMP-9) levels, analyzed the influencing factors of residual recurrence after hysteromyomectomy. Results Among the 68 patients, postoperative residual recurrence occurred in 7 cases (10.29%). Age, number of fibroids, location of fibroids and MMP-9 level were compared between the residual or recurrent group and the nonresidual or recurrent group, the differences were statistically significant (P<0.05). Multivariate Logistic regression analysis found that Age<40 years old, number of fibroids≥4, intramural fibroids, MMP-9 level≥200 ng/L were all the influencing factors for residual recurrence after hysteromyomectomy (P<0.05). Conclusion Patients with uterine fibroids have a certain residual recurrence rate after removal, and intervention should be carried out according to the influencing factors of postoperative residual recurrence to improve the prognosis of patients. 2021 Vol. 28 (21): 115-117 [Abstract] ( 40 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 118 The effect of laparoscopic pelvic autonomic nerve-preserving extensive hysterectomy for cervical cancer ZHENG Zhi-ping； ZENG Yu-fei； ZHENG De-mei Objective To explore the effect of laparoscopic pelvic autonomic nerve-preserving extensive hysterectomy on patients with cervical cancer. Methods A total of 70 patients with cervical cancer admitted to the Fifth People′s Hospital of Shangrao City from February 2017 to June 2019 were selected and divided into the control group (35 cases)and the observation group (35 cases) according to the random number table method.The control group received extensive hysterectomy under traditional laparoscopic surgery treatment, and the observation group received laparoscopic extensive hysterectomy with preserving pelvic autonomic nerve treatment. The postoperative follow-up time was 7 days.The surgery related conditions, postoperative urodynamic indexes, postoperative bladder function, postoperative rectal function before and after treatment were compared between the two groups. Results The time of operation in the observation group was longer than that of the control group, and the time of hospital stay in the observation group was shorter than that of the control group, the differences were statistically significant (P<0.05). After the surgery, the frequency of urination daily in the observation group was less than that of the control group, the difference was statistically significant (P<0.05). After the surgery, the residual urine volume, the bladder capacity during initial urge to urinate, and the bladder capacity at initial urinary intention in the observation group were smaller than those of the control group, the maximum urination volume daily in the observation group were greater than those of the control group, the differences were statistically significant (P<0.05). After the surgery, the incidences of abdominal pressure, urinary retention, bladder dysfunction, and urinary incontinence in the observation group was lower than that of the control group, the differences were statistically significant (P<0.05). After the surgery, the defecation time and exhaust time in the observat ion group was shorter than that of the control group, and the differences were statistically significant (P<0.05). There were no statistically significant in vaginal resection length and intraoperative blood loss between the two groups (P>0.05). Conclusion Laparoscopic pelvic autonomic nerve-preserving extensive hysterectomy has little effect on the patient′s urinary tract function, tectal function, bladder function in the treatment of cervical cancer, the patient′s hospital stay is short, and the treatment effect is better. 2021 Vol. 28 (21): 118-120转124 [Abstract] ( 45 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 121 Analysis of diagnostic value of CMA technology for CNV abnormalities in NT-thickening fetuses HU Wen-xiang Objective To explore the diagnostic value of chromosomal microarray analysis (CMA) in fetal copy number abnormality (CNV) with cervical transparent layer (NT) thickening. Methods The clinical data of 70 pregnant women with fetal NT≥2.5 mm indicated by ultrasound in Ganzhou Maternal and Child Health Hospital from September 2019 to September 2020 were retrospectively analyzed. All of them received traditional G-banting chromosome analysis and CMA technique detection. CNV high-throughput sequencing (CNV-Seq) technology as the standard, the diagnostic value of traditional G-banding chromosome analysis and CMA detection were compared and the detection rate of CNV abnormality was compared.Results The result of CMA was in good agreement with that of CNV-Seq(Kappa=0.944),which was better than that of traditional G-banding chromosome analysis (Kappa=0.424). The area under curve (AUC) of CNV abnormalities diagnosed by CMA was greater than that by traditional G-banding chromosome analysis, the difference was statistically significant (P<0.05). The detection rate of CNV abnormalities by CMA was higher than that by traditional G-banding chromosome analysis, and the diagnostic sensitivity was higher than that by traditional G-banding chromosome analysis, the differences were statistically significant (P<0.05). Conclusion Diagnostic value of CMA technology is high for CNV abnormalities in NT-thickening fetuses, which can increase detection rate and diagnostic sensitivity of CVN. 2021 Vol. 28 (21): 121-124 [Abstract] ( 31 ) HTML (30 KB)  PDF  (0 KB)  ( 8 ) 125 Clinical effect of Levothyroxine Sodium Tablets in the treatment of hypothyroidism during pregnancy and observation on the changes of thyroid hormone levels LYU Dong-mei; SHANG Min-jie; TIAN Xiao-ying; PAN Zhong-min ;CHEN Shuang Objective To analyze the clinical effect of Levothyroxine Sodium Tablets in the treatment of hypothyroidism during pregnancy and its influence on the change of thyroid hormone level. Methods A total of 46 patients with hypothyroidism during pregnancy who were treated in Jinzhou Maternal and Child Hospital from July 2018 to April 2019 were selected as the research subjects, and they were divided into control group (23 cases) and treatment group (23 cases) by coin toss. The control group was treated with Guifu Dihuang Pills and the treatment group was treated with Levothyroxine Sodium Tablets.The therapeutic effect and the levels of thyroid stimulating hormone(TSH),free triiodothyronine (FT3) and free thyroxine (FT4) were compared between two groups. Results The total effective rate of the treatment group (95.65%) was higher than that of the control group (69.57%), and the difference was statistically significant(P<0.05). Before treatment, there was no significant difference in TSH, FT3 and FT4 levels between the two groups (P>0.05). After treatment, TSH level of the two groups was lower than before treatment, FT3 and FT4 indexes were higher than before treatment, and TSH index level of the treatment group was lower than the control group, FT3 and FT4 indexes were higher than the control group, the differences were statistically significant (P<0.05). Conclusion Levothyroxine Sodium Tablets can improve the level of thyroid hormone in patients with hypothyroidism during pregnancy, and the therapeutic effect is remarkable. 2021 Vol. 28 (21): 125-127 [Abstract] ( 37 ) HTML (33 KB)  PDF  (0 KB)  ( 8 ) 128 Comparison of the effect of single/double uterine incision in patients with dangerous placenta previa WANG Lie Objective To compare the effect of single/double uterine incision in patients with dangerous placenta previa. Methods Clinical data of 120 patients with dangerous placenta previa admitted to the General Hospital of Northern Theater Command from January 2018 to January 2020 were retrospectively analyzed, and they were divided into double incision group (41 cases) and single incision group (79 cases) according to the surgical methods. The single incision group was treated with single incision and the double incision group was treated with double incision. The surgical indicators (operative time, hospitalization recovery time, intraoperative blood loss and hysterectomy rate), the incidence of complications (coagulation dysfunction, bladder injury and postoperative fever) and patient satisfaction were compared between the two groups. Results The operation time and hospitalization recovery time of the double-incision group were longer than those of the single incision group, the intraoperative blood loss was less than that of the single incision group, and the hysterectomy rate was lower than that of the single incision group, the differences were statistically significant (P<0.05). The rate of postoperative coagulation dysfunction in the double incision group was lower than that in the single incision group, and the incidence of postoperative fever was higher, the differences were statistically significant (P<0.05). There was no significant difference in the incidence of postoperative bladder injury between the two groups (P>0.05). The patient satisfaction of the double incision group was 92.68%, higher than that of the single incision group (78.48%), the difference was statistically significant (P<0.05). Conclusion Uterine double incision in cesarean section for patients with dangerous placenta previa can reduce intraoperative blood loss, reduce the hysterectomy rate and the risk of postoperative abnormal blood coagulation, which is beneficial to improve patient satisfaction. 2021 Vol. 28 (21): 128-130转133 [Abstract] ( 46 ) HTML (32 KB)  PDF  (0 KB)  ( 8 ) 131 In vitro study and clinical analysis of apical sealing performance of bioceramic material iRoot SP SHU Shan Objective To observe the apical sealing performance of bioceramic material iRoot SP in vitro, so as to provide reference for its application in the treatment of pulp and periapical diseases. Methods From September 2018 to September 2020, the extracted teeth of patients in the Department of Oral and Maxillofacial Surgery of Jiangmen Stomatological Hospital in Guangdong Province were collected, and 120 isolated single root canal teeth were selected as the in vitro study samples of this study. Root canals were prepared to F2 with Protaper nickel titanium machine using the downward method, and the extracted teeth of the included groups were randomly divided into group A, group B, group C, group D, 30 cases in each group. Group A and group B were filled with hot gutta percha, AH-Plus was used in group A, iRoot SP was used in group B, group C was treated with iRoot SP single point filling, group D did not use sealer, only hot gutta percha vertical pressure filling. After the specimens were treated with dye penetration method and transparent tooth method, the length of dye penetration into root canal was measured. The permeation effects of the four groups were compared. Results The infiltration distance in group A, B, C were shorter than group D, while the infiltration distance in group B were shorter than those in group A and D, the differences were statistically significant (P＜0.05). There was no significant difference in the infiltration distance between group A and group C (P＞0.05). Conclusion In the root canal treatment of isolated teeth, different materials of root canal sealers have different effects. The difference of apical sealing performance between iRoot SP and AH-Plus is small, while the single tip method of root canal filling iroot SP apical sealing can also obtain good root canal sealing, which provides a reference for finding a more simple and effective root canal filling method in clinic. 2021 Vol. 28 (21): 131-133 [Abstract] ( 36 ) HTML (27 KB)  PDF  (0 KB)  ( 7 ) 134 Efficacy and safety of guided tissue regeneration technology in patients with periodontal disease CHEN Hao Objective To explore the application effect of guided tissue regeneration technology in the efficacy and safety of patients with periodontal disease. Methods A total of 64 patients with periodontal disease admitted to Shuncheng Branch of Fushun Stomatological Hospital from January 2019 to January 2020 were selected as study subjects and divided into the observation group (32 cases) and the control group (32 cases) according to random number table method.The control group adopted conventional treatment measures, while the observation group adopted guided tissue regeneration technology measures. The total therapeutic efficiency, the total incidence of adverse reactions, the total incidence of adverse emotions, and quality of life scores of the two groups were compared. Results The total effective rate and quality of life scores of the observation group after treatment were higher than those of the control group, the differences were statistically significant (P＜0.05). The total incidence of adverse reactions and adverse emotions of the observation group after treatment were significantly lower than those of the control group, with statistically significant differences(P＜0.05). Conclusion Guided tissue regeneration technique is more effective and safe in the treatment of patients with periodontal disease. The total effective rate, quality of life score are higher, and the incidence of adverse reactions and bad emotions were lower, so it is worthy of clinical promotion and application. 2021 Vol. 28 (21): 134-136 [Abstract] ( 49 ) HTML (30 KB)  PDF  (0 KB)  ( 7 ) 137 Effect of compound trabeculectomy in the treatment of glaucoma patients and its influence on the quality of life DU Wei-feng ；HAN Ying-jun； CHEN Jian-li； SUN Dan Objective To investigate the effect of compound trabeculectomy in the treatment of glaucoma patients and its influence on the quality of life. Methods A total of 30 patients with glaucoma admitted to Beijing Renhe Hospital from October 2018 to October 2019 were selected as the research objects. According to the random number table method, they were divided into the control group (15 cases) and the study group (15 cases). The control group was treated with conventional trabeculectomy, the study group was treated with compound trabeculectomy. The intraocular pressure, anterior chamber depth and quality of life were compared between the two groups. Results The intraocular pressure of the study group after treatment was lower than that of the control group, and the depth of the anterior chamber of the study group was higher than that of the control group, the differences were statistically significant (P<0.05). There were no significant differences in intraocular pressure and anterior chamber depth between the two groups before treatment (P>0.05). The intraocular pressure after treatment was lower than that before treatment, and the depth of anterior chamber after treatment was higher than before treatment, the differences were statistically significant (P<0.05). The quality of life score of the study group after treatment was higher than that of the control group, and the difference was statistically significant (P<0.05).There was no statistically significant difference in the quality of life score between the two groups (P>0.05). The quality of life scores of the two groups after treatment were higher than those before treatment, and the differences were statistically significant (P<0.05). Conclusion Compound trabeculectomy is effective in treating glaucoma patients, it can effectively improve intraocular pressure, anterior chamber depth, and improve the quality of life. 2021 Vol. 28 (21): 137-139转143 [Abstract] ( 35 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 140 Evaluation of the application effect of Pranoprofen Eye Drops after pterygium surgery FANG Zhen Objective To observe the efficacy of Pranoprofen Eye Drops after pterygium surgery. Methods The clinical data of 70 eyes of 70 patients with primary pterygium who received pterygium excision combined with corneal limbal stem cell transplantation from January to December 2018 in Fuqing City Hospital were analyzed retrospectively. The patients were divided into the control group and the observation group according to random number table method,35 cases in each group. Both groups were given Levofloxacin Eye Drops and recombinant human epidermal growth factor eye drops after surgery, the observation group was additionally given Pranoprofen Eye Drops. The curative effect of the two groups was compared. Results There was no significant difference in the corneal epithelial healing time between the two groups (P＞0.05). The pain scores at 48 h and 72 h after operation in the observation group were lower than those in the control group, the differences were statistically significant (P＜0.05). There was no significant difference in pain score between the two groups at 1 week after operation (P＞0.05). The duration of conjunctival graft edema in the observation group was (16.63±4.77)d, which was shorter than that in the control group ([20.43±5.57] d), the difference was statistically significant (P＜0.05). The patients were followed up for 6 months, the curative effect of the observation group was better than that of the control group, the cure rate of the observation group (80.00%) was higher than that of the control group (57.14%), the differences were statistically significant (P＜0.05). There was no significant difference in the incidence of keratolysis between the two groups (P＞0.05). Conclusion The use of Pranoprofen Eye Drops after pterygium surgery can reduce the inflammatory reaction and partially relieve pain, which also can improve the curative effect and cure rate. 2021 Vol. 28 (21): 140-143 [Abstract] ( 48 ) HTML (34 KB)  PDF  (0 KB)  ( 6 ) 144 Application effect of Nitrous Oxide, Midazolam combined with Fentanyl in painless gastroenteroscopy LI Jun-da；DONG Si-chao；YANG Ru-xiao； SHEN Jian-gang； HUANG Jin-wen； LI Ruo-qun；FU Zhao-xia； HU Xian-fu Objective To investigate the application effect of Nitrous Oxide, Midazolam and Fentanyl in painless gastroenteroscopy. Methods A total of 240 patients who received gastro-colonoscopy in Longhua District People′s Hospital of Shenzhen from August 2016 to August 2017 were selected as the research subjects. According to the method of gastro-colonoscopy, the patients were divided into gastroscopy group (120 cases) and colonoscopy group (120 cases). Gastroscopy group was divided into P group, X group, MF group and MFX group according to random number table method, with 30 cases in each group. Colonoscopy group was divided into P′ group, X′ group, MF′group and MFX′group according to random number table method, with 30 cases in each group. Group P and P′received general endoscopy, group X and X′ received Nitrous Oxide sedation, group MF and MF′received Midazolam combined with Fentanyl sedation, and group MFX and group MFX′ received Nitrous Oxide combined with Midazolam and Fentanyl sedation. The changes of heart rate (HR), blood pressure,blood oxygen saturation (SpO2), sedative effect, adverse events of gastroscopy and pain degree of colonoscopy were compared between four groups respectively of gastroscopy and colonoscopy. Results ①In gastroscopy, HR, SBP and DBP in the four groups were higher than before, and SpO2 was lower than before, the differences were statistically significant (P<0.05). HR, SBP, DBP and SpO2 in the four groups all recovered to their pre-inspection levels. The sedative effect of MFX group was better than that of MF group and X group, the difference was statistically significant (P<0.05). The incidence of adverse events in group X, MF and MFX was lower than that in group P, the difference was statistically significant (P<0.008). ②In colonoscopy, HR in P′group was higher than before, the difference was statistically significant (P<0.05). There was no significant difference in SBP, DBP and SpO2 in each group (P>0.05), and they all recovered to the pre-examination level after examination. There was no significant difference in the sedative effect of X′group, MF′ group and MFX′group (P>0.05). The analgesic efficiency of MF′group and MFX′ group was higher than that of P′group, the differences were statistically significant (P<0.008). Conclusion In painless gastroenteroscopy, the combination of Nitrous Oxide, Midazolam and Fentanyl has a good sedative and analgesic effect, which is worth popularizing clinically. 2021 Vol. 28 (21): 144-148 [Abstract] ( 50 ) HTML (42 KB)  PDF  (0 KB)  ( 7 ) 149 Effect observation of ultrasonic-guided saphenous nerve block in great saphenous vein exfoliation ZHANG Wen-ting； YUAN Wan-qiu Objective To investigate the effect of ultrasound-guided saphenous nerve block in the removal of the great saphenous vein. Methods A total of 60 patients with varicose veins of lower extremities who underwent great saphenous vein stripping in People′s Hospital of Pingxiang City from March 2019 to may 2020 were selected and divided into control group and study group according to double-blind method, with 30 cases in each group.The control group received laryngeal mask general anesthesia and the study group received ultrasound-guided cryptonerve block. Hemodynamic indexes mean arterial pressure (MAP) and heart rate (HR) before surgery (T0), 30 min after surgery (T1), 1 h after surgery (T2) and 30 min after surgery (T3) in the two groups were compared. Visual analogue scale (VAS) was used to evaluate the degree of postoperative pain, and the early postoperative time of getting out of bed was compared between the two groups. Results There was no statistically significant difference in MAP and HR between the two groups at T0(P>0.05). The MAP and HR at T1, T2 and T3 in the control group were higher than that of T0, and the differences were statistically significant (P<0.05). There were no statistically significant differences in MAP, HR at T1, T2, T3 and T0 in the study group (P>0.05). The MAP and HR at T1, T2 and T3 in the study group were lower than those in the control group, and the differences were statistically significant (P<0.05). There were no statistically significant differences in VAS score between the two groups at 1 h and 48 h after surgery (P>0.05). VAS scores at 4, 8 and 24 h after surgery in the study group were lower than those in the control group, and the differences were statistically significant (P<0.05).The early postoperative activity time of the study group was shorter than that of the control group, and the difference was statistically significant (P<0.05). Conclusion The application of ultrasonic-guided saphenous nerve block in the great saphenous vein exfoliation can maintain the patients′ intraoperative hemodynamics stable, and the analgesic effect is ideal, which is conducive to the early postoperative recovery of the patient, so it can be regarded as a reliable and effective anesthesia block option, which is worthy of clinical development. 2021 Vol. 28 (21): 149-151转155 [Abstract] ( 41 ) HTML (36 KB)  PDF  (0 KB)  ( 7 ) 152 Application of total intravenous anesthesia with Propofol combined with Remifentanil in children with inguinal hernia in early childhood LIN Xiong-da ；PAN Shuang-yan Objective To explore the effect of Propofol combined with Remifentanil total intravenous anesthesia in children with inguinal hernia (IH) in early childhood. Methods The clinical data of 80 infants with IH admitted to Quanzhou Maternal and Child Health Hospital and Children′s Hospital from September 2019 to September 2020 were retrospectively analyzed. According to different anesthesia schemes, they were divided into the study group and the control group, with 40 cases in each group. The control group received combined intravenous anesthesia with Sevoflurane and Remifentanil, and the study group received total intravenous anesthesia with Propofol combined with Remifentanil.The effect of anesthesia, recovery from anesthesia, levels of inflammatory factors (C-reactive protein [CRP], tumor necrosis factor-α [TNF-α]) 3, 24 h after operation and the total incidence of adverse reactions were compared between the two groups. Results There was no statistically significant difference in the anesthesia effect between the two groups (P>0.05). The time to open eyes, the time to remove the laryngeal mask, and the recovery time of spontaneous breathing in the study group were shorter than those in the control group, and the differences were statistically significant (P<0.05).There were no statistically significant differences in serum CRP and TNF-α levels between the two groups before surgery(P>0.05). The serum CRP and TNF-α levels of the study group were lower than those of the control group at 3, 24 h after surgery, and the differences were statistically significant (P<0.05). The serum CRP and TNF-α levels of the two groups at 12 h after operation were lower than those at 3 hours after operation, and the differences were statistically significant (P<0.05). The total incidence of adverse reactions in the study group was 2.50% (1/40), which was lower than 20.00%(8/40)in the control group,and the difference was statistically significant(P<0.05).Conclusion Propofol combined with remifentanil for total intravenous anesthesia in children with IH in early childhood can effectively improve the recovery from anesthesia, reduce the impact on serum inflammatory factors, with fewer adverse reactions and high safety. 2021 Vol. 28 (21): 152-155 [Abstract] ( 42 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 156 Effect of ultrasound-guided thoracic paravertebral block on analgesic and cellular immune function in patients with video-assisted single-hole thoracic surgery NI Xin-xin Objective To explore the effect of ultrasound-guided thoracic paravertebral block (TPVB) on analgesic and cellular immune function in patients with video-assisted single-hole thoracic surgery. Methods A total of 60 patients who underwent selective single-port thoracoscopic partial pneumonectomy in Wuxi Huishan District People′s Hospital from March to August 2020 were selected as the research subjects. According to random number table method, they were divided into TPVB group and control group, with 30 patients in each group. In TPVB group, T4-5, T6-7 thoracic paravertebral nerve block was performed under ultrasonic guidance after intubation induced by general anesthesia. After confirming that there was no blood, no gas, and no cerebrospinal fluid, 10 mL 0.5% ropivacaine was injected, respectively. In the control group, 10 mL of normal saline was injected into the same thoracic paravertebral space. The number of sufentanil and methydroxyamine additions during surgery, visual analogue scale (VAS) scores 24 and 48 h after surgery, the number of effective pressure on patient controlled intravenous analgesia (PCIA), and the changes of CD4+,CD8+and CD3+before and 24 and 48 h after anesthesia induction were compared between the two groups. Results The number of intraoperative sufentanil and hydroxyamine supplementation in TPVB group was less than that in control group, the difference was statistically significant (P<0.05). 24 and 48 h after surgery, the VAS scores of TVPB group were lower than the control group, and the effective times of PCIA compression were less than the control group, the differences were statistically significant (P<0.05). There was no significant difference in the levels of CD4+, CD8+ and CD3+ between the two groups before anesthesia induction (P>0.05). 24 h after operation, CD4+, CD8+, CD3+ levels in TPVB group were higher than those in control group, 48 h after operation, CD8+ and CD3+ levels in TPVB group were higher than those in control group, the differences were statistically significant (P<0.05). Conclusions Ultrasound-guided thoracic paravertebral nerve block can not only improve the effect of analgesia, but also maintain the T-lymphocyte subgroup level and reduce the inhibition of cellular immunity of patients with uniportal video-assisted thoracoscopic surgery. 2021 Vol. 28 (21): 156-159 [Abstract] ( 48 ) HTML (41 KB)  PDF  (0 KB)  ( 7 ) 160 Observation on the early clinical effect of Danggui Sini Decoction plus or minus in the treatment of postmenopausal low back pain ZENG Su-ping； ZHANG Si-qing ；LI Qing-jiao； ZHU Chun-xia； HU Zhu-lian； YANG Jia-lin； XU Hui Objective To study the effect of early treatment with Danggui Sini Decoction plus or minus in postmenopausal patients with low back pain. Methods A total of 60 patients with postmenopausal low back pain admitted to the Department of Gynecology and Obstetrics, Maternal and Child Health Care Hospital of Xingguo County from November 2018 to November 2020 were selected as the research subjects and divided into control group and treatment group by random number table method, with 30 patients in each group. The control group was treated with conventional anti-osteoporosis regimen. The treatment group was treated with Danggui Sini Decoction plus or minus scheme. The total effective rate of drug therapy was compared between the two groups. The total incidence of adverse reactions between the two groups was compared and recorded. The time of pain symptoms to disappear, the time when lumbar and back mobility returned to normal, and the total time of hospitalization were compared between the two groups. The pain degree, quality of life and Oswestry disability index (ODI) scores were compared between the two groups before and after treatment. Bone mineral density before and after treatment was compared between the two groups. Results The total effective rate of drug therapy in treatment group was higher than that in the control group, the difference was statistically significant (P<0.05). The total incidence of adverse drug reactions in the treatment group was lower than that in the control group, and the difference was statistically significant (P<0.05). The time of pain disappearance, the time of low back activity returning to normal and the total time of hospitalization in the treatment group were shorter than those in the control group, and the differences were statistically significant (P<0.05). After treatment, ODI score and visual analogue scale (VAS) score in the treatment group were lower than those in the control group, and the MOS item short from health survey (SF-36) score in the treatment group was higher than that in the control group, the differences were statistically significant (P<0.05). After treatment, there was no significant difference in T value of bone mineral density between the two groups (P>0.05). Conclusion Early treatment of postmenopausal low back pain patients with Danggui Sini Decoction plus or minus scheme can reduce the total incidence of adverse reactions, relieve pain in a short time, restore the activity of the back and back, shorten the total time of disease control and treatment, and significantly improve the total effective rate. 2021 Vol. 28 (21): 160-163 [Abstract] ( 45 ) HTML (38 KB)  PDF  (0 KB)  ( 8 ) 164 Clinical effect of Erxian Decoction combined with Heche Dazao Capsules in the treatment of menopausal syndrome DOU Xiao-ni ；WANG Jun-qin ；WEI Wei Objective To explore the clinical effect of Erxian Decoction combined with Heche Dazao Capsules in the treatment of menopausal syndrome. Methods The clinical data of 48 patients with climacteric syndrome admitted to the Outpatient Department of Traditional Chinese Medicine of Beijing Shijingshan Hospital from July 2017 to July 2019 were retrospectively analyzed. According to different treatment methods, they were divided into the study group (24 cases) and the control group (24 cases). The study group was treated with Erxian Decoction Combined with Heche Dazao Capsules, and the control group was treated with Heche Dazao Capsules. The total effective rate and the improvement of symptoms before and after treatment were compared between the two groups. Results The total effective rate of the study group was 95.83%, which was higher than that the control group of 75.00%, the difference was statistically significant (P<0.05). The score of main clinical symptoms in the study group after treatment was lower than that in the control group, the difference was statistically significant (P<0.05). During the treatment, there was no adverse reactions occurring in the two groups. Conclusion Erxian combined with Heche Dazao Capsules has significant effect in the treatment of climacteric syndrome, which can improve the clinical symptoms and is safe and effective. 2021 Vol. 28 (21): 164-167 [Abstract] ( 37 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 168 Effect and safety of acupuncture and moxibustion combined with rehabilitation training in the treatment of dysphagia after stroke YUAN Song-bai； ZHENG Xu；HE Xiao-ying Objective To explore the effect and safety of acupuncture combined with rehabilitation training in the treatment of dysphagia after stroke. Methods A total of 94 patients with post-stroke swallowing dysfunction admitted to the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine from October 2018 to June 2020, using a randomlist method,they were divided into control groups, observation group, 47 cases in the group. The control group used rehabilitation function training treatment methods, and the observation group used acupuncture combined with rehabilitation function training treatment. The clinical therapeutic effect, swallowing function score, complications, and quality of life score were compared. Results After treatment, the treatment effect of the observation group was better than that of the control group, and the difference was statistically significant (P<0.05). Before treatment, there was no statistically significant difference in swallowing function score between the two groups (P>0.05); after treatment, the swallowing function score of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05). During the treatment period, the total incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). After treatment, the quality of life scores of the observation group were higher than those of the control group, and the differences were statistically significant (P＜0.05). Conclusion Through the implementation of acupuncture and rehabilitation function training, the swallowing function of stroke is significantly improved, and the quality of life is greatly improved, and the patient′s complication are relatively fewer, and the clinical application is good, it is worthwhile. 2021 Vol. 28 (21): 168-170 [Abstract] ( 46 ) HTML (33 KB)  PDF  (0 KB)  ( 8 ) 171 Effect of Sanwei Wenzhong Bao on clinical efficacy and quality of life in patients with epigastric pain identified assyndrome of deficiency cold QIN Peng； LI Chuang； SHEN Chen Objective To analyze the effect of Sanwei Wenzhong Bao on clinical efficacy and quality of life in patients with epigastric pain with the syndrome of deficiency cold. Methods A total of 96 patients with epigastric pain identified as syndrome of deficiency cold in the 968th Hospital of the Joint Logistics Support Force of the Chinese People′s Liberation Army from November 2018 to November 2020 were selected as the research subjects. The patients were divided into an observation group (48 cases) and a control group (48 cases) by a random number table method. Patients in the control group were treated with conventional Western medicine, while patients in the observation group were treated with Sanwei Wenzhong Bao on the basis of the control group. The clinical efficacy, traditional Chinese medicine syndrome scores, the World Health Organization quality of life (WHOQOL) score and the incidence of adverse reactions were compared between the two groups. Results The clinical overall response rate (95.83%) of the observation group was higher than that of the control group accounting for 70.83% (P<0.05). The symptom scores of abdominal distension and fullness, hiccough and belching, tastelessness with preference for warmth of the observation group were lower than those in the control group after treatment (P<0.05). The WHOQOL score of the observation group was higher than that of the control group after treatment (P<0.05). There was no statistical significance in the total incidence of adverse reactions between the observation group (8.33%) and the control group (6.25%) (P>0.05). Conclusion Sanwei Wenzhong Bao can effectively relieve the clinical symptoms of patients with epigastric pain identified as syndrome of deficiency cold and improve the quality of life with fewer adverse reactions. 2021 Vol. 28 (21): 171-173 [Abstract] ( 42 ) HTML (31 KB)  PDF  (0 KB)  ( 8 ) 174 Analysis of influencing factors and pathogen in critically ill patients complicated with bloodstream infection CHEN Ling-juan； PENG Xiao-fei； LI Yu-zhen；ZHONG Guo-quan；ZHANG Zhong-wen； XU Ling-qing Objective To investigate the influencing factors and pathogen in critically ill patients complicated with bloodstream infection. Methods A total of 162 patients complicated with bloodstream infections admitted to the Critical Care Department of the Sixth Affiliated Hospital of Guangzhou Medical University from January to June 2020 were selected as the observation group, and a total of 162 patients without bloodstream infection were selected as the control group. Data were collected and the influencing factors and pathogens in critically ill patients complicated with bloodstream infections were analyzed. Results The results of univariate analysis suggested that the observation group′s age,cerebrovascular disease, diabetes, central venous catheterization, mechanical ventilation period > 5 d, and the use of antibacterial drugs within 30 d before admission were statistically different from those in the control group after comparison (P<0.05). The results of multivariate analysis suggested that age ≥60 years old (β=1.606,OR=4.982,95%CI=2.862-8.671), cerebrovascular disease (β=1.203, OR=3.329, 95%CI=1.969-5.628), diabetes (β=0.774, OR=2.168, 95%CI=1.345-3.495), mechanical ventilation period > 5 d (β=1.613, OR=5.017, 95%CI=3.115-8.080), antibacterial drugs used within 30 d before admission (β=0.900, OR=2.460, 95%CI=1.461-4.143) were high-risk factors for critical ill patients complicated with bloodstream infections (P<0.05). A total of 251 pathogenic bacteria were separated from hemoculture samples of 162 patients in the observation group, including 155 Gram-negative bacteria (61.75%), 86 Gram-positive bacteria (34.27%), and 10 fungi (3.98%). Conclusion Critically ill patients complicated with bloodstream infections are related to age, mechanical ventilation period, use of antibacterial drugs, complication of cerebrovascular diseases, and diabetes. Gram-negative bacteria are the main pathogenic bacteria of critically ill patients complicated with bloodstream infections. Clinical nursing interventions should be strengthened for various risk factors to reduce the occurrence of bloodstream infections.Targeting on the pathogenic bacteria, drug susceptibility tests are carried out, and antibacterial drugs are reasonably selected according to the test results to enhance the therapeutic effect. 2021 Vol. 28 (21): 174-177 [Abstract] ( 48 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 178 Analysis of the relationship between the expressions of ANP, cTnI and arrhythmia in hypertensive patients with chronic kidney disease HUANG Li Objective To investigate the expression levels of serum atrial natriuretic peptide (ANP) and cardiac troponin(cTnI) in patients with hypertensive with chronic kidney disease (HCKD) and their cardiac arrhythmia (CA). Methods A total of 136 patients with HCKD admitted to the Fifth People′s Hospital of Jianli City, Hubei Province from June 2017 to June 2019 were selected as the research objects, according to whether there was arrhythmia, they were divided into CA group (92 cases with arrhythmia) and non CA group (44 cases without arrhythmia), serum ANP and cTnI levels were compared among different subgroups. The relationship between heart rate variability (HRV) in CA group and non CA group was compared. The correlations between serum ANP, cTnI and HRV were analyzed. Results With the increase of lowns grade, the expression levels of ANP and cTnI in serum increased gradually and the difference was statistically significant (P<0.05). The levels of SDNN, SDANN, rMSSD and pNN50 in CA group were lower than those in CA group the difference was statistically significant (P<0.05). The ANP level was negatively correlated with SDNN, SDANN,rMSSD, pNN50 level in CA group the difference was statistically significant (r=-0.679, -0.603, -0.472, -0.738, P<0.05). Conclusion Serum ANP and cTnI levels may be related to the severity of Ca in patients with HCKD, the higher the LOWNS classification, the higher the severity of CA. The detection of serum ANP and cTnI levels has certain value for the evaluation of CA. 2021 Vol. 28 (21): 178-181 [Abstract] ( 34 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 182 Application effect of four items of liver fiber detection in the diagnosis of liver fibrosis LIU Zhi-ru Objective To explore the application effect of four items of liver fiber detection in the diagnosis of liver fibrosis. Methods The clinical data of 400 patients with suspected liver fibrosis in Fushun Infectious Disease Hospital from February 2017 to February 2019 were retrospectively analyzed. A total of 158 patients were selected as the observation group, and they were divided into viral liver cirrhosis, cholasis hepatic cirrhosis, alcoholic cirrhosis, liver cirrhosis caused by autoimmune liver disease and stasis cirrhosis according to the condition. While 202 patients with noncirrhosis treated at the same period were selected as the control groups. Hyaluronic acid (HA), laminin (LN), collegen type Ⅳ(CⅣ) and procollagen ⅢN-terminal propeptide (PⅢNP) were measured in the two groups, and the diagnostic sensitivity, specificity and accuracy of clinical liver fiber were recorded. Results The HA, LN, CⅣand PⅢNP of the observation group were higher than those of the control group, the differences were statistically significant (P<0.05). The HA, LN, CⅣand PⅢNP of different cirrhosis types of the observation group were compared, with statistically significant differences (P<0.05). The sensitivity, specificity and accuracy of the four tests were 90.12% (146/162), 94.96%(226/238), 93.00% (372/400) respectively. Conclusion In the diagnosis of liver cirrhosis, the four detection of liver fiber has significant significance in the evaluation of liver function. 2021 Vol. 28 (21): 182-184 [Abstract] ( 46 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 185 Study on the correlation between work stress, sleep quality and mood of psychiatric nurses DING Wen-juan； YUAN Yu-bo； LI Yang； CAI Qi-mei ；WU Hai-xia ；XI Jiao-long Objective To explore the correlation between work stress, sleep quality and mood of psychiatric nurses.Methods A total of 200 clinical first-line nurses in the Third People′s Hospital of Ganzhou from October 2019 to September 2020 were selected as the survey subjects by cluster sampling method. The work pressure, sleep quality and mood were assessed by self-made psychiatric nurses′ stress survey scale, Pittsburgh sleep quality index (PSQI) and symptom checklist 90 (SCL-90), and the Pearson correlation was used to analyze the correlation among them. Results All dimensions of work stress of 200 nurses were positively correlated with sleep quality and mood (P<0.05). Conclusion The work stress, sleep quality and mood of psychiatric nurses are closely related. Corresponding intervention and improvement measures should be formulated in nursing management to reduce the work stress and improve sleep quality and mood of nurses. 2021 Vol. 28 (21): 185-187 [Abstract] ( 65 ) HTML (31 KB)  PDF  (0 KB)  ( 5 ) 188 Statistical analysis of the incidence of malignant tumors in Chenzhou City from 2015 to 2018 ZHOU Dan-ni;WU Zhi-jian; WANG A-jin;ZHANG Wen-han;CAO Hong;SHI Wen-yuan Objective To analyze the occurrence of malignant tumors in Chenzhou City from 2015 to 2018, and to provide basis for the scientific prevention and treatment of malignant tumors in this region. Methods The diagnostic data of inpatients in secondary and tertiary hospitals in Chenzhou City were collected from 2015 to 2018, and according to the ICD-10 international statistical classification of diseases and related health problems, the incidence of malignant tumors (C00-C97) in different age groups and different genders were statistically analyzed. Results From 2015 to 2018,the number of malignant tumors reported in Chenzhou City was 63 048, with 13 930, 15 087, 16 837 and 17 194 cases respectively, increasing year by year for four years. The top five malignant tumors reported were bronchial and lung malignant tumors, hepatic and intrahepatic bile duct malignant tumors, gastric malignant tumors, breast malignant tumors,and rectal malignant tumors. Among the 6 age groups, the patients with high incidence were 40～<65 years and ≥65 years, with 35 774 cases and 23 463 cases reported respectively. The number of cases reported by malignant tumor in male was 37 042, male reported cases in the first five for bronchial and pulmonary malignant tumor, the liver and intrahepatic bile duct malignant tumor, stomach malignant tumor, rectal malignant tumor, colon malignant tumor. Malignant tumor in women to report cases were 26 006 cases, women reported cases in the first five for the breast malignant tumor, bronchus and pulmonary malignant tumor, cervical malignant tumor, stomach tumor, colon malignant tumor.Conclusion From 2015 to 2018, the number of malignant tumors reported in Chenzhou City has been increasing year by year. The incidence of malignant tumors is mainly middle-aged and elderly. The incidence of malignant tumors in males is significantly higher than that in females. The distribution of major malignant tumors in males and females is different. The effective prevention and control measures should be formulated according to the distribution characteristics of malignant tumors in this region. 2021 Vol. 28 (21): 188-191 [Abstract] ( 44 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 192 Investigation and analysis on anxiety of medical secondary vocational school students during the epidemic period of COVID-19 JIANG Lin-hui； LU Bi-yan； DENG Guo-jin ；XU Chuan-xia Objective To understand the anxiety and influencing factors of medical secondary vocational school students during the epidemic period of COVID-19. Methods From March 15th to 17th, 2020, 1600 medical students from 5 secondary vocational schools in Guangdong Province were investigated with a convenient sampling method by using the self-rating anxiety scale (SAS) and self-established general questionnaire through the network platform. Results A total of 143 cases (9.2%) of anxiety symptoms were detected among medical secondary vocational school students during the epidemic period of COVID-19. The score of SAS was (37.31±9.42) points, and the SAS score of the female students was higher than that of male students, the difference was statistically significant (t=3.551, P=0.000). The SAS score and anxiety detection rate of students who had taken public transportation were higher than those who had not taken public transportation, the differences were statistically significant (t=2.849, P=0.004; χ2=7.780, P=0.005). The results of regression analysis showed that students′ gender and whether they had taken public transportation had no effect on the anxiety (P>0.05). Conclusion Anxiety symptoms of medical secondary vocational school students are common during the epidemic period of COVID-19. Schools should establish a sound and perfect mental health screening plan and carry out mental health education activities in multiple dimensions. 2021 Vol. 28 (21): 192-195转204 [Abstract] ( 52 ) HTML (39 KB)  PDF  (0 KB)  ( 6 ) 196 Influence of family doctor team intervention on the treatment compliance of patients with hypertension in the community XIAO Qiu-yan； YU Ming； NIE Lei Objective To explore the influence of family doctor team intervention on the treatment compliance of patients with hypertension in the community. Methods From January 2019 to January 2020, 242 patients with hypertension with low compliance registered and managed in the Tongle North Community Health Service Center were selected.The patients were divided into the control group （121 cases) and the intervention group (121 cases) by the random number table method. The control group was given routine health education, while the intervention group was given community family doctor team intervention. After the intervention, a questionnaire was conducted again to observe and compare the compliance of each item and the regulation of blood pressure between the two groups. Results After the intervention, the blood pressure of the intervention group was lower than that of the control group, the difference was statistically significant (P<0.05). After the intervention, the treatment compliance scores of the two groups were higher than those before the intervention, and the differences were statistically significant (P<0.05). The treatment compliance score in the intervention group after intervention was higher than that in the control group, and the difference was statistically significant (P<0.05). After the intervention, the compliance scores of patients in the intervention group in term of compliance with doctors and drug-taking behaviors, daily life management eating behaviors, other daily life management behaviors, and tobacco and alcohol addiction management behaviors were all higher than those in the control group, and the differences were statistically significant (P<0.05). Conclusion Family doctor team intervention can improve the compliance of hypertensive patients in the community, thus more effective control of blood pressure. 2021 Vol. 28 (21): 196-200 [Abstract] ( 47 ) HTML (42 KB)  PDF  (0 KB)  ( 8 ) 201 Health examination analysis of 86 female monks in Tianhujing Temple,Sanming City DU Huang; CHEN Hong-bin; HUANG Kang-ming; CHEN Hui-ling; ZHAO Yu Objective To understand the basic health condition of female monks in the Tianhujing Temple in Sanming City, so as to improve social attention to the temple monks. Methods A total of 86 female monks in Tianhujing Temple(Tianhujing temple group) received a routine physical examination on August 2, 2020, including routine workups of gynecology, internal medicine, surgery, traditional Chinese medicine, massage, acupuncture, otorhinolaryngology, electrocardiogram, B-ultrasound (liver, gallbladder, pancreas, spleen, kidneys, breast, uterus double appendages), chest X-ray,blood routine, fecal routine, urine routine, biochemical complete set, hepatitis B antibodies, alpha-fetoprotein (AFP)and carcinoembryonic antigen (CEA). A total of 2464 women from Shanghecheng Health Service Station in Xubi Community of Sanming City (community group) from July 1st to August 1st, 2020 were selected as a control cohort. Results In the Tianhujing temple group, 69 cases were diagnosed with diseases, accounting for 80.23% of the total number of people, and the diseases involved multiple systems, 17 cases were scored as healthy under disease screening system,accounting for 19.76% of the total number of people. There was a difference in disease spectrum between the two groups. There were statistically significant differences in the detection rates of anemia, breast hyperplasia, and uterine fibroids between the two groups (P<0.05). Conclusion The temple monks have special disease characteristics. It is of great significance to strengthen the physical examination of temple monks and improve the basic medical facilities of the temple. 2021 Vol. 28 (21): 201-204 [Abstract] ( 44 ) HTML (32 KB)  PDF  (0 KB)  ( 8 ) 205 Study on the impact of DRG payment mode reform on medical behavior of doctors MA Yan Objective To explore the impact of diagnosis related group (DRG) payment reform on medical behavior of doctors. Methods In this study, 84 valid questionnaires were selected from the Maternal and Child Health Hospital of Bao′an District, Shenzhen from June 2020 to May 2021, and analyzed and studied from three dimensions: the cognition of doctors of DRG payment mode, the impact of DRG payment reform on doctors′ behavior and the impact of DRG payment on the quality of health services. Results The results showed that 88.1% of doctors said they were generally aware of or very familiar with the reform of DRG payment methods, and 61.9% of doctors said they supported the reform of DRG payment methods. The majority of doctors believed that the most prominent advantage of DRG payment was to regulate the behavior of diagnosis and treatment (70.2%) and to promote graded diagnosis and treatment (69.0%), while the biggest disadvantage was that the autonomy of doctors was too limited (72.6%). The results showed that 48.8% of doctors believed that DRG payments had a significant impact on medical behavior; 83.3% of the doctors thought that the implementation of DRG payment method would not affect the conditions of patients admitted; 84.5% of doctors believed that there was an increase in concern about medical costs after the implementation of DRG payment; 90.5% of doctors believed that the implementation of DRG payment would not affect the number of outpatient visits. 70.2%,83.3% and 63.1% of the doctors thought that the rate of patient readmission rate, the incidence of complications and the average hospitalization cost per time were not affected by the reform of DRG payment method, respectively. The results showed that 70.2%, 83.3% and 63.1% doctors thought that the rate of patient readmission, complication rate and average hospitalization cost per time were not affected by the reform of DRG payment method. Conclusion By studying the relationship between DRG payment system and medical behavior, the medical behaviors of medical staff can be further standardized, it also provides decision support for hospitals to carry out DRG pilot, and promotes the further improvement of DRG payment reform. 2021 Vol. 28 (21): 205-208转213 [Abstract] ( 37 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 209 Analysis of 178 serious adverse drug reactions LI Xiang； XU Ping Objective To analyze the characteristics and rules of serious adverse drug reactions (ADR) in Heyuan People′s Hospital, to provide references for clinical rational use of drugs. Methods A total of 178 patients with severe ADR who were reported to Guangdong ADR Monitoring System by Heyuan People′s Hospital from January 2018 to December 2019 were selected as the research subjects for retrospective analysis, including the general conditions of severe ADR patients, combined medication, the route of administration, the types of drugs, and the organs/system and other content. Results Of 178 serious ADR cases, the male to female ratio was 1∶0.91, with slightly more males than females.The number of patients aged >60 years was the largest, accounting for 42.70%. The number of severe ADR cases caused by one drug combination was the largest, accounting for 87.09%. Intravenous infusion was the most important way to cause severe ADR, accounting for 83.71%. The number of severe ADR cases caused by anti-infective drugs was the largest, accounting for 27.53%, followed by traditional Chinese medicine injections, accounting for 11.80%. Among the anti-infective drugs causing severe ADR, quinolones were the most, accounting for 28.57%. The most severe ADR involved organs/systems was skin and its appendages. New severe ADR and severe ADR accounted for 37.08% and 62.92%, respectively. After corresponding treatment, 147 cases of severe ADR were improved, 28 cases were cured, 2 cases were unknown, and 1 case was not improved. Conclusion It is necessary to strengthen the supervision of anti-infective drugs and traditional Chinese medicine injections, and standardize their use; and strengthen the monitoring of serious ADR, reduce or avoid the occurrence of serious ADR, and promote rational clinical use of drugs. 2021 Vol. 28 (21): 209-213 [Abstract] ( 44 ) HTML (37 KB)  PDF  (0 KB)  ( 7 ) 214 Application effect of competency-oriented phased training in the standardized training of cardiothoracic surgery residents CAI Long-ren； WU Ze-qin； WANG Qin ；LI Hai-ping ；PENG Yun Objective To explore the application effect of competency-oriented phased training in the standardized training of cardiothoracic surgery residents. Methods From January 2018 to December 2019, 30 trainees from the standardized training of cardiothoracic surgery residents in Ganzhou People′s Hospital were selected as the research subjects. Random touched balls were used to divide them into two groups. The control group (15 cases) received traditional training and the observation group (15 cases) received competency-oriented phased training. The learning effect of students under two different training methods was compared. Results The scores of each ability of the normalized training trainees in the two groups after training were higher than those before training, and the differences were statistically significant (P<0.05). After training, the scores of ward round ability and management of medical files in the observation group were all higher than in the control group, the differences were statistically significant (P<0.05). There were no statistically significant differences in the scores of trainees before training between the two groups, such as professional ability and ability to deal with diseases independently(P>0.05).There were no statistically significant differences in theoretical assessment and skill assessment of trainees before training between the two groups (P>0.05).After training,the performances of the trainees in theoretical assessment and skill assessment in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).After training,the performances of the trainees in theoretical assessment and skill assessment in the two groups were higher than those before training, and the differences were statistically significant (P<0.05). Conclusion The competency-oriented phased training in the standardized training of cardiothoracic surgery residents not only improves the students′ ability to deal with diseases independently and professionally, but also improves theoretical performance and operational skills, which has application value. 2021 Vol. 28 (21): 214-217 [Abstract] ( 35 ) HTML (34 KB)  PDF  (0 KB)  ( 6 ) 218 Application of DingTalk software in laboratory management and teaching of histology and embryology laboratory DING Ya-li Objective To explore the value of DingTalk software in laboratory management and teaching of histology and embryology. Methods A total of 80 medical students who studied in the histology and embryology laboratory in our university at 2018—2019 and 2019—2020 were selected as the research objects, including the control group in 2018—2019 (40 cases) and the observation group in 2019—2020 (40 cases). The control group was adopted the traditional laboratory teaching concept, while the observation group was combined with nailing software, and the pre-class preview rate, course attendance rate and homework completion rate in the two groups were compared, the evaluation of teachers′ teaching effect between two groups of students were compared, and the theoretical and practical ability test results of histology and embryology examination at the end of semester were counted. Results The pre-class preparation rate, course attendance rate and homework completion rate in the observation group were higher than control group, the differences were statistically significant (P<0.05). The scores of the observation group on the teaching fun, content specificity, and practical integration of the teacher′s teaching effect evaluation indicators in the observation group were higher than those in the control group, the differences were statistically significant (P<0.05). The scores of theoretical and practical ability test of histology and embryology examination at the end of semester in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). Conclusion The application of DingTalk software in teaching management of histology and embryology laboratory can cultivate students′active learning ability and improve teaching quality. 2021 Vol. 28 (21): 218-220转224 [Abstract] ( 31 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 221 Application research of standardized patients in comprehensive nursing training in higher vocational colleges CHEN Bao-ling; HU Ying-hui; QI Wen-yan; TANG Ting; ZOU Ying Objective To explore the teaching effect of standardized patients in comprehensive nursing training in higher vocational colleges. Methods From May 2020 to June 2020, two classes were randomly selected from the nursing specialty of grade 2018 in Jiangxi Health Vocation College, which were divided into study group (62 cases) and control group (163 cases) respectively. In the course of comprehensive nursing training, the study group introduced standardized patients, while the control group adopted conventional teaching methods, and then at the end of the course, the students′ classroom satisfaction, communication abilities and humanistic care quality were compared between the two groups. Results The students′ classroom satisfaction, communication abilities and humanistic care quality in the study group were higher than those in the control group, with statistically significant differences (P<0.05). Conclusion The introduction of standardized patients in comprehensive nursing training can improve students′ comprehensive abilities of learning interest, efficient communication and humanistic care, and promote the effective integration between school education and clinical practice. 2021 Vol. 28 (21): 221-224 [Abstract] ( 37 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 225 Exploration of applied intelligent vocational education platform in experimental teaching of biochemistry HUANG Hui Intelligent vocational education is a free resource sharing platform to promote the informatization of higher vocational education, trying to use the intelligent vocational education platform in teaching can integrate all kinds of teaching resources to arouse students′ interest in learning biochemistry experiments. Based on the introduction of intelligent vocational education platform into the biochemistry experiment course of clinical medical students in Zhaoqing Medical College to carry out research on the reform of curriculum content, teaching methods, assessment methods and curriculum standards. Through the discussion of the various functions of the intelligent vocational education platform and the application of these functions in the biochemical experiment class, the original teaching content of teachers is changed from the middle class to the pre-class and post-class. This research not only can keep pace with the times,improve students′ autonomous learning ability, practical ability, exploration and analysis ability, communication, teamwork ability and so on. It can improve the classroom attraction and interactivity of biochemical experiment teaching and promote the teaching. 2021 Vol. 28 (21): 225-227转231 [Abstract] ( 36 ) HTML (32 KB)  PDF  (0 KB)  ( 9 ) 228 Effects of health education combined with family support on glycemic control, self-efficacy and quality of life in elderly diabetic patients YI Yu-ling； YUAN Zhen-lan； YANG Mei-xiang； YI Qi； YUAN Lin； YUAN Ai-hua； ZOU Zi-wan Objective To investigate the effects of health education map combined with family support on blood glucose control, self-efficacy and quality of life in elderly diabetic patients. Methods A total of 100 diabetes patients in the Department of Endocrinology of the Second People′s Hospital of Yichun City from January 2020 to December 2020 were selected as the research objects. They were divided into the control group and the observation group according to the random number table method, with 50 cases in each group. The control group was treated with traditional health education, while the observation group was treated with health education chart and family support. After intervention, the blood glucose level, self-efficacy score and life quality score of patients in the two groups were compared. Results The self-efficacy evaluation scores of the observation group were higher than those of the control group, the 2 h postprandial blood glucosee and glycosylated hemoglobin were lower than those of the control group after intervention, and the quality of life score was higher than that of the control group, the differences were statistically significant (P<0.05).Conclusion The implementation of health education map combined with family support intervention for elderly diabetic patients can significantly improve their sense of self-efficacy, improve the quality of life, and promote blood glucose control in patients. 2021 Vol. 28 (21): 228-231 [Abstract] ( 39 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 232 Application effect of team-based learning combined with case-based learning teaching method in clinical practice of endodontics MA Guo-jing； WANG Lu； REN Qiang Objective To study the application effect of team-based learning (TBL) combined with case-based learning(CBL) teaching method in clinical practice of dental pulp disease. Methods A total of 54 interns in the First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology from October to November 2019 were selected as the research objects. The interns were divided into traditional teaching group (n=27) and TBL combined CBL teaching group (n=27) by random number table method. The traditional teaching group used traditional teaching methods, and the TBL combined with the CBL teaching group performed TBL combined with CBL teaching method. The assessment results (theory, medical record writing), comprehensive ability (course evaluation, comprehension ability, expression ability, analysis ability and cooperation ability), evaluation of teaching methods (finding improvement in solving ability, improvement in hands-on ability, helpful clinical work, and promotion of improvement in clinical creative thinking ability) and satisfaction with teaching of interns of the two groups were compared. Results The theory and medical record writing assessment scores of TBL combined with CBL teaching group were higher than those of traditional teaching group, and the differences were statistically significant (P<0.05). The proportions of TBL combined with CBL teaching group in improving discovery and solution ability, practical ability, helping clinical work and improving clinical creative thinking ability were higher than those of traditional teaching group, and the differences were statistically significant (P<0.05). The comprehensive ability assessment scores, such as curriculum evaluation,comprehension ability, expression ability, analysis ability and cooperation ability in the TBL combined with CBL teaching group were all higher than those of traditional teaching group and the differences were statistically significant (P<0.05). The teaching satisfaction of TBL combined with CBL group (92.59%) was higher than that of traditional teaching group (55.56%), and the difference was statistically significant (P<0.05). Conclusion The application of TBL combined with CBL teaching method in the clinical practice of dental and endodontic diseases is beneficial to improve the students′ mastery of theory and skills, comprehensive ability, and can improve teaching satisfaction. 2021 Vol. 28 (21): 232-235 [Abstract] ( 47 ) HTML (37 KB)  PDF  (0 KB)  ( 7 ) 236 Application effect of health education in nursing of children with asthma YANG Yue； YU Rui-xue； ZHANG Xi-ruo；WANG Hong-fei； YANG Yang Objective To explore the application effect of health education in the nursing of children with asthma.Methods A total of 100 children with asthma diagnosed and treated in Hongqi Hospital Affiliated to Mudanjiang Medical University from January 2020 to January 2021 were selected and divided into experimental group and control group by the random number table method, with 50 cases in each group. The control group used routine clinical nursing without special intervention, while the experimental group continued to carry out health education for children and their families based on routine nursing. The recurrence frequency of asthma, family members′ knowledge of asthma and the satisfaction with nursing methods were collected and statistically analyzed. Results The recurrence rate of asthma in children in the experimental group was lower than that in the control group, and the difference was statistically significant (P<0.05). The family members′ knowledge of asthma and total satisfaction with nursing methods in the experimental group were higher than those in the control group, and the differences were statistically significant (P<0.05). Conclusion Health education nursing can significantly reduce the recurrence rate of asthma in children, strengthen the mastery of disease knowledge of children′ families, and improve nursing satisfaction, which is worthy of wide application in clinical practice. 2021 Vol. 28 (21): 236-238转242 [Abstract] ( 42 ) HTML (34 KB)  PDF  (0 KB)  ( 6 ) 239 Effect of systematic nursing mode on compliance of immunotherapy in children with allergic rhinitis ZHAI Yan-yan； HU Shui-hua； WANG Kun； JIANG Lan Objective To explore the effect of systematic nursing mode on the compliance of immunotherapy in children with allergic rhinitis (AR). Methods From August to December 2018, 30 cases of children with AR receiving immunotherapy in the Second Affiliated Hospital of Nanchang University were selected as the control group, and from January to May 2019, 30 cases of children with AR receiving immunotherapy were selected as the experimental group. The patients in the control group were intervened with conventional scheme. On this basis, the experimental group was intervened with systematic nursing intervention. The treatment compliance, quality of life (physiological function, psychological function, living environment, social function) before and after the intervention, and nursing satisfaction of children′s family members were compared between the two groups. Results The treatment total compliance of the experimental group (93.33%) was higher than that of the control group (70.00%), the difference was statistically significant(P<0.05). Before the intervention, there were no statistically significant differences in the scores of physiological function, psychological function, living environment and social function between the two groups (P＞0.05). After the intervention, the scores of physiological function, psychological function, living environment and social function of the two groups were higher than those before the intervention, the scores of physiological function, psychological function, living environment and social function of the experimental group were higher than that of the control group, the differences were statistically significant （P<0.05）. Nursing total satisfaction of the experimental group (100.00%) was higher than that of the control group (70.00%), the difference was statistically significant (P<0.05). Conclusion The clinical significance of systematic nursing intervention in the immunotherapy of children with AR is significant, which can effectively improve the treatment compliance, reduce the occurrence of adverse reactions, and improve the nursing satisfaction of children′s families. 2021 Vol. 28 (21): 239-242 [Abstract] ( 39 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 243 Application effect of integrated medical care under the concept of rapid rehabilitation in the perioperative nursing of hepatectomy WU Na； ZHANG Lin； LIU Hong； ZHOU Yong Objective To study the application effect of the integrated medical care under the cancept of rapid rehabilitation in the perioperative nursing of hepatectomy. Methods Eighty patients with liver diseases admitted to Pingxiang People′s Hospital from July 2019 to December 2020 were selected as the research subjects. They were divided into athe control group and the study group by the random number table method, 40 cases in each group. In the control group, integrated medical care was used, and in the study group, the integrated medical care under the concept of rapid rehabilitation was adopted. They were both provided with nursing one month. The postoperative anal exhaust time, liquid food ingestion time, hospital stay, changes in serum albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT) levels before and after intervention, and the incidence of complications during the intervention were compared between the two groups. Results The postoperative anal exhaust time, liquid food ingestion time, and hospital stay in the study group were shorter than those in the control group, the differences were statistically significant (P<0.05). The serum AST and ALT levels after the intervention of the two groups were lower than those before the intervention, and the serum AST and ALT levels of the study group were lower than those in the control group, the differences were statistically significant (P<0.05). The serum albumin levels of the two groups after intervention were higher than before the intervention, and the serum albumin level of the study group was higher than that of the control group,the differences were statistically significant (P<0.05). The total incidence of complications in the study group was lower than that of the control group (15.00%), the difference was statistically significant (P<0.05). There were no statistically significant differences in the levels of various indicators of liver function (P＞0.05). Conclusion The concept of rapid rehabilitation of integrated medical care in the perioperative care of hepatectomy can significantly shorten the recovery time of patients after surgery, reduce the incidence of complications, and is safe and effective. Meanwhile, it can effectively improve the level of patients′ liver function and improve the prognosis. 2021 Vol. 28 (21): 243-245转249 [Abstract] ( 35 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 246 Study on the construction and application effect of cluster-based evidence-based nursing in operating room of vidian endoscopic surgery ZHOU Yuan； YANG Dan； FU Jin-ping； YIN Lin； CHEN Wei-bin Objective To study the construction and application effect of the clustered evidence-based nursing program in the operating room of vidian endoscopic surgery. Methods A total of 62 patients from Yichun People′s Hospital who underwent endoscopic vidian neurectomy from October 2019 to December 2020 were selected as the research objects,by random number table method, they divided into the control group and the observation group, 31 cases in each group.The control group used conventional nursing care, and the observation group used the operating room clustered evidence-based nursing program, the pain, nursing satisfaction, anxiety and depression scores of the two groups were compared. Results After nursing, the visual analogue (VAS) score of pain of the observation group was lower than that of the control group, and the duration of pain was shorter than that of the control group, the differences were statistically significant (P＜0.05）. After nursing, the nursing total satisfaction of the observation group was higher than that of the control group, and the difference was statistically significant (P＜0.05）. After nursing, self-rating anxiety scale (SAS)and self-rating depression scale (SDS) scores of the observation group were lower than those of the control group, and the differences were statistically significant (P＜0.05）. Conclusion The clustered evidence-based nursing program in the operating room for patients undergoing endoscopic vidian neurotomy can reduce the pain of the patient, shorten the duration of the pain, reduce the negative emotion of the patient, and obtain the patient′s high evaluation of the nursing. 2021 Vol. 28 (21): 246-249 [Abstract] ( 45 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 250 Ameliorative effect of early nursing on psychology，complications and quality of life of patients with macular edema QIU Yuan-yuan； LI Sheng； DU Ying Objective To explore the ameliorative effect of early care on improving the psychology, complications and quality of life of patients with macular edema. Methods A total of 78 cases macular edema treated in Dalian Third People′s Hospital from November 2018 to June 2020 were selected as the research objects, according to random number table method, they were divided into the control group (39 cases) and research group (39 cases). The control group used conventional nursing, the research group used the early nursing intervention. The negative emotions, the quality of life(CLVQOL) score and the incidence of complications were compared between two groups. Results The scores of Zung′s self-rating anxiety scale (SAS) and self-rating depression scale (SDS) two groups after nursing were lower than before nursing,and the total CLVQOL score was higher than before nursing,the differences were statistically significant(P<0.05);the SAS and SDS scores of the research group were lower than those of the control group after nursing,and the total CLVQOL score was higher than tthat of the control group, the differences were statistically significant (P<0.05). The total incidence of complications in the reaearch group (2.56%) was lower than that in the control group (15.38%), and the difference was statistically significant (P<0.05). Conclusion Early nursing can improve the negative emotions of patients with macular edema, improve the quality of life, reduce the incidence of complications, has the value of promotion. 2021 Vol. 28 (21): 250-252 [Abstract] ( 44 ) HTML (31 KB)  PDF  (0 KB)  ( 8 ) 253 Application effect of multidisciplinary collaborative pain management model in the perioperative period of thoracoscopic lobectomy ZHONG Ming-lian Objective To investigate the application effect of multidisciplinary collaborative pain management model in the perioperative period of thoracoscopic lobectomy. Methods A total of 88 patients with thoracoscopic lobulotomy admitted to Ganzhou People′s Hospital in Jiangxi Province from November 2018 to October 2020 were selected as the research subjects, and were divided into the observation group (44 cases) and the control group (44 cases) according to random number table method. The control group was treated with routine perioperative nursing, and the observation group was treated with multidisciplinary cooperative pain management mode on the basis of the control group, until the patients were discharged from hospital. The pain degree, postoperative recovery time and the incidence of complications were compared between the two groups. Results There was no significant difference in visual analogue scale (VAS)scores between the two groups at 4 hours after operation (P＞0.05). The VAS scores of the observation group at 24 and 72 hours after operation were lower than those of the control group, the first exhaust and hospitalization time were shorter than those of the control group, and the differences were statistically significant (P<0.05). The total incidence of postoperative complications in the observation group was 9.09%, lower than 25.00% in the control group, and the difference was statistically significant (P<0.05). Conclusion The multidisciplinary collaborative pain management model can effectively reduce the postoperative pain of patients undergoing thoracoscopic lobectomy, promote postoperative recovery and reduce postoperative complications. 2021 Vol. 28 (21): 253-255转259 [Abstract] ( 44 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 256 Influence of pulmonary function rehabilitation training combined with holistic nursing on pulmonary function and exercise endurance of patients with chronic obstructive pulmonary disease LOU Li-hua Objective To explore the influence of pulmonary function rehabilitation training combined with holistic nursing on pulmonary function and exercise endurance of patients with chronic obstructive pulmonary disease.(COPD)Methods From May 2019 to October 2020, 100 patients with COPD in the First People′s Hospital of Fuzhou City were selected as the research objects, and they were divided into the control group and the observation group according to the random number table method, 50 cases in each group. The control group was given holistic nursing mode, while the observation group was given pulmonary function rehabilitation training combined with holistic nursing mode. The changes of forced vital capacity in the first second (FEV1), the ratio of forced expiratory volume in the first second to forced vital capacity (FEV1/FVC), the modified dyspnea index (mMRC) and 6-minute walk test (6 MWT) were evaluated, and the changes of quality of life were investigated by St. George′s respiratory quality score (SGRO) were observed between the two groups. Results There were no significant differences in FEV1 and FEV1/FVC between the two groups before intervention (P＞0.05). After intervention, the lung function indexes of the two groups were higher than those before intervention, and the lung function indexes of the observation group after intervention were higher than those of the control group after intervention, the differences were statistically significant (P<0.05). There were no significant difference in mMRC, 6MWT length and SGRO score between the two groups before intervention (P＞0.05). After intervention, the mMRC scores of the two groups were higher than those before intervention, and the 6MWT length was longer than that before intervention, the mMRC score of the observation group after intervention was lower than that of the control group, and the 6MWT was longer than that of the control group after intervention, the differences were statistically significant (P<0.05). Conclusion The application of pulmonary function rehabilitation training combined with holistic nursing is helpful to improve the pulmonary function of patients with COPD, enhance their exercise endurance and improve their quality of life, and the effect is good. 2021 Vol. 28 (21): 256-259 [Abstract] ( 49 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 260 Application of health education model of multi-disciplinary collaborative diagnosis and treatment combined with intelligent nursing system in family rehabilitation of patients with chromic obstructive pulmonary disease CUI Xin-hao； GAO Ying ；ZHANG Jian-rong； ZENG Li-li； WU Miao-xia； HUANG Ding-lan Objective To explore the application effect of health education model of multidisciplinary collaboration diagnosis and treatment (MDT) combined with intelligent nursing system in home rehabilitation of patients with chronic obstructive pulmonary disease (COPD). Methods A total of 120 cases of COPD patients treated in Dongguan Houjie Hospital Affiliated to Guangdong Medical University from November 2018 to December 2019 were selected as the research objects,according to the grouping of lottery were randomly divided into the control group(60 cases)and study group(60 cases). The control group was given traditional routine health education, the study group was given MDT combined wisdom of health education, nursing system of health knowledge mastering situation that occupy the home, the degree of anxiety, depression, quality of life score, pulmonary function index, patient satisfaction were compared between two groups. Results The scores of health knowledge questionnaire and quality of life scale in the study group were higher than those in the control group, and the differences were statistically significant (P＜0.05). The anxiety and depression scores of the study group were lower than those of the control group, the differences were statistically significant (P＜0.05）, the chronic obstructive pulmonary disease assessment test scale (CAT) scores at 1, 3, 6 months after intervention in the study group were lower than those of the control group, the differences were statistically significant (P＜0.05）. The 1 second (FEV1%), percentage of forced expiratory volume to the predicted value (FEV1/FVC%) of the study group at 1, 3, 6 months after intervention were higher than those of the control group, the differences were statistically significant (P＜0.05）, and at 6 months after the intervention, total satisfaction in the study group was higher than that of the control group, difference was statistical significance (P ＜0.05）. Conclusion In the process of family rehabilitation health education for COPD patients, the application of MDT combined with wisdom nursing system health education model can improve patients′ grasp of health knowledge, promote the improvement of patients′ lung function, relieve their negative emotions, improve the quality of life, and improve patient satisfaction. 2021 Vol. 28 (21): 260-264 [Abstract] ( 32 ) HTML (42 KB)  PDF  (0 KB)  ( 7 ) 265 Application effect of internet+ collaborative nursing service model in nursing home chronic wounds of the elderly XIAO Jin Objective To explore the application effect of the internet+ collaborative nursing service model in nursing home chronic wounds for the elderly. Methods A total of 108 patients with chronic wounds admitted to Xiaogan Central Hospital from August 2019 to August 2020 were selected as the research objects. They were divided into the control group (54 cases) and the observation group (54 cases) according to the random number table method. The control group used routine nursing, the observation group adopts conventional internet+ collaborative nursing. The pain score, pressure ulcer healing scale (PUSH) score, wound healing time, wound temperature, bacteria positive rate, chronic woundrelated knowledge score, self-care ability were compared between the two groups. Results The visual simulation method(VAS) and PUSH scores of the observation group after nursing were lower than those of the control group, and the differences were statistically significant (P<0.05). The wound healing time of the observation group was shorter than that of the control group, the wound temperature of the observation group after nursing was higher than that of the control group, and the positive rate of bacteria (3.70%) was lower than that of the control group (16.67%), the differences were statistically significant (P<0.05). The scores of chronic wound-related knowledge and ESCA self-care ability measurement scale （ESCA） scores of the observation group after nursing were higher than those of the control group, and the differences were statistically significant (P<0.05). Conclusion The application of the internet+ collaborative nursing service model in the elderly home chronic wound care can reduce the pain degree of patients, improve their wound healing, shorten their wound healing time, increase their wound temperature, reduce the appearance of positive bacteria on the wound, and increase his knowledge of chronic wounds and his self-care ability. 2021 Vol. 28 (21): 265-268 [Abstract] ( 46 ) HTML (36 KB)  PDF  (0 KB)  ( 9 ) 269 Influence of core temperature and bad mood for breast carcinoma patients by operating room thermal insulation combined with comfort nursing LI Si ;MA Cai-xia; GUO Hui Objective To approach influence of core temperature and bad mood for breast carcinoma patients by operating room thermal insulation combined with comfort nursing. Methods The 120 cases breast carcinoma patients treated in Fujian Provincial Hospital from October 2019 to 2020 October were selected as study objects, they were divided into the control group and the detection group by random number table method, 60 cases in each group. Routine nursing measures in operating room of control group was used, the operating room thermal insulation combine with comfort nursing was used in the detection group. The temperature changing of two groups was detected，depression and anxiety score of two groups were detected，nursing satisfaction and compliance of two groups were detected. Results The temperature before operation, before intubate, surgery′s over time, depression and anxiety score of two groups were compared, the differences were no statistical significance (P＞0.05). The temperature of detection group before intubate, after intubate 60 min, surgery′s over time and before operation were compared, the differences were no statistical significance(P＞0.05). The temperature of control group before intubate, surgery′s over time and before operation were compared, the differences were no statistical significance (P＞0.05), temperature after intubate 60 min of detection group was higher than that of the control group, temperature after intubate 60 min of control group was higher than before operation, after nursing, depression and anxiety score of the control group and detection group were lower than before nursing in the same group, depression and anxiety score of detection group after nursing were lower than those of the control group, the nursing satisfaction and compliance of detection group were lower than those of the control group, the differences were statistical significance (P<0.05). Conclusion The application of breast carcinoma patients by operating room thermal insulation with comfort nursing, which could increase core temperature, improve bad mood，increase nursing satisfaction and compliance. 2021 Vol. 28 (21): 269-272 [Abstract] ( 38 ) HTML (34 KB)  PDF  (0 KB)  ( 8 ) 273 Application effect of continuous nursing in patients with acute exacerbation of chronic obstructive pulmonary disease LIN Bi-lan Objective To explore approach effect of continuous nursing in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods The 100 cases COPD acute exacerbation patients in the First Affiliated Hospital of Fujian Medical University from August 2019 to August 2020 were selected as research objects, which were divided into the control group and the detection group according to the random slip method, 50 cases in each group. The control group was used routine nursing, the continuous nursing intervention was used the detection group.The forced expiratory volume in one second (FEV1), forced vital capacity (FVC), maximum mean mid-stream velocity(MMEF), arterial partial pressure of oxygen (PaO2), partial pressure of carbon dioxide in arterial blood (PaCO2), fibrinogen (FBG), D-dime (D-D), the self nursing score and life quality score of two group before intervention and after intervention were detected, the satisfaction and compliance of two group were detected. Results Before intervention, the FEV1, FVC, MMEF, PaO2, PaCO2, FBG, D-D of two group were compared, the differences were no statistical significance (P＞0.05); after intervention, the FEV1, FVC, MMEF, PaO2 of two group were higher than before intervention, Pa-CO2, FBG, D-D were lower than before intervention, the FEV1, FVC, MMEF, PaO2 of the detection group were higher than those of the control group, PaCO2, FBG, D-D were lower than those of the control group，the differences were statistical significance (P<0.05). Before intervention, the self nursing score and life quality score of two group were compared, the differences were no statistical significance (P＞0.05); after intervention, the self nursing score and life quality score of two group were higher than before intervention, the self nursing score and life quality score of the detection group were higher than those of the control group, the total satisfaction and compliance of the detection group were higher than that of the control group, the differences were statistical significance (P<0.05). Conclusion The application effect of continuous nursing in patients with acute exacerbation of COPD,which could improve pulmonary function and blood gas analysis result of patients, decrease FBG, D-D, increase self nursing level and life quality of patients. 2021 Vol. 28 (21): 273-276 [Abstract] ( 36 ) HTML (37 KB)  PDF  (0 KB)  ( 7 )

Copyright © Editorial Board of 中国当代医药 Supported by:Beijing Magtech