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2021 Vol. 28, No. 14 Published: 2021-05-18

	4	Effect of isokinetic muscle strength training on the rehabilitation of upper limb motor function for stroke patients with hemiplegia:a Meta-analysis
		ZHANG Hao-tian；ZHANG Qian；ZHU Ting； CIREN Zhuo-ma； BIAN Ba
		Objective To systematically evaluate the effect of isokinetic muscle strength training on the rehabilitation of upper limb motor function for stroke patients with hemiplegia.Methods Literature of randomized controlled trials on the effect of isokinetic muscle strength training on the rehabilitation of upper limb motor function for stroke patients with hemiplegia was retrieved from PubMed and CNKI database by computer,and the retrieval time was from the establishment of the database to October 2020.According to the literature quality assessment criteria recommended by the Cochrane manual,the quality of the included literatures was evaluated,and RevMan 5.3 and Stata 15.0 software were used for Meta-analysis.Results Seven articles were included,with a sample size of 456 cases.Meta-analysis results showed that isokinetic muscle strength training could improve the peak torque(PT),average power(AP)and total work(TW)of elbow joints in stroke patients with hemiplegia,the mean difference(MD)of outcome indicators and its 95% confidence interval(CI)were:2.06(95%CI[1.06,3.05],P＜0.01),6.83(95%CI[-0.38,14.03],P＜0.05),1.69(95%CI[-0.23,3.61],P＜0.05),4.03(95%CI[2.79,5.26],P＜0.01),15.38(95%CI[-6.02,36.78],P＜0.05),28.98(95%CI[25.37,32.58],P＜0.01).Isokinetic muscle strength training could reduce the improved Ashworth scale(MAS)score in stroke patients with hemiple gia,but the difference was not statistically significant,the outcome index MD and its 95%CI were-0.02(95%CI[-0.04,0.01],P＞0.05).The results of Egger′s test on funnel plots showed that there was no publication bias in the Meta-analysis of this study.Conclusion Isokinetic muscle strength training has a positive therapeutic effect on the rehabilitation of upper limb motor function for stroke patients with hemiplegia.In the future studies,high-quality and large-sample clinical randomized controlled trials would be needed to further verify the effect of isokinetic muscle strength training to improve the rehabilitation of upper limb motor function for stroke patients with hemiplegia.
		2021 Vol. 28 (14): 4-7转12 [Abstract] ( 48 ) HTML (37 KB) PDF (0 KB) ( 6 )

	8	Feasibility study of combined detection of five urinary modified nucleosides and plasma EBV-DNA in the diagnosis of nasopharyngeal carcinoma
		MAO Fei-xia； ZHANG Yi-min； ZHANG Jian-ying
		Objective To explore the feasibility of combined detection of five urinary modified nucleosides and plasma EBV-DNA in the diagnosis of nasopharyngeal carcinoma.Methods A total of 56 patients with nasopharyngeal carcinoma treated in Zhejiang Cancer Hospital from January to June 2020 were selected as the nasopharyngeal carcinoma group and 32 healthy subjects during the same period were selected as the healthy control group.Liquid chromatography-tandem mass spectrometry was employed to measure the concentrations of modified nucleosides pseudouridine(Pseu),2-O-methylguanosine(m2G),1-methyladenosine(m1A),6-methyladenosine(m6A)and 1-methylguanosine(m1G)in urine samples.The levels of Pseu,m2G,m1A,m6A and m1G in urine samples of the two groups were compared.Fluorescent quantitative polymerase chain reaction was employed to measure the level of the plasma EBV-DNA in peripheral blood samples collected from all the subjects.Receiver operating characteristic(ROC)curve was made to evaluate the diagnostic value of single detection and combined detection of urinary nucleosides and plasma EBV-DNA.Results The levels of Pseu,m2G,m1A and m1G in the nasopharyngeal carcinoma group were higher than those in the healthy control group,the differences were statistically significant(P＜0.05).The level of the plasma EBV-DNA in the nasopharyngeal carcinoma group was higher than that in the healthy control group,the difference was statistically significant(P＜0.05).The area under the curve(AUC)of the combined detection was higher than that of m2G,m1A,Pseu,m1G and EBV-DNA in individuals,the differences were statistically significant(P＜0.05).In the nasopharyngeal carcinoma patients,the Pseu concentration was positively correlated with clinical stage and lymph node metastasis(r=0.474,0.406,P＜0.01).Conclusion The urinary modified nucleosides Pseu,m2G,m1A and m1G may be small molecular markers for the diagnosis of nasopharyngeal carcinoma.The combined detection of the four urinary nucleosides with plasma EBV-DNA may help to improve the diagnostic efficiency of nasopharyngeal carcinoma.
		2021 Vol. 28 (14): 8-12 [Abstract] ( 55 ) HTML (41 KB) PDF (0 KB) ( 5 )

	13	Dynamic changes of lymphocyte subsets in patients with diffuse large Bcell lymphoma before and after chemotherapy and its significance
		YU Lu；DING Kai-yang
		Objective To investigate the changes of lymphocyte subsets(CD3+,CD4+,CD8+,CD4+/CD8+)in peripheral blood before and after chemotherapy in patients with diffuse large B-cell lymphoma(DLBCL)and their clinical significance.Methods A total of 56 patients with DLBCL who visited Provincial Hospital affiliated to Anhui Medical University for the first time from May 2018 to May 2020 were retrospectively selected as the research subjects,and all patients were pathologically confirmed.According to the ratio of CD4+/CD8+in peripheral blood before chemotherapy,the patients were divided into two groups as the elevated/normal group(group A)39 cases and the reduced group(group B)17 cases.All patients received R-CHOP regimen after admission,After four cycles of chemotherapy,the patients were divided into elevated/normal group(group C)31 cases and decreased group(group D)25 cases according to the ratio of CD4+/CD8+in peripheral blood,and analyzed the changes of immune function and its relationship with prognosis in patients with different clinical characteristics.Results After treatment,the levels of CD3+and CD8+in two groups were higher than before treatment,while the level of CD4+/CD8+was lower than before treatment,the differences were statistically significant(P＜0.05).After treatment,the patients in group A had less progression than group B,and the progression-free survival time in group A was longer than that in group B,the differences were statistically significant(P＜0.05).The incidence of thrombocytopenia in group D was higher than that in group C,and the difference was statistically significant(P＜0.05).Conclusion The immunestatus of patients with diffuse large B-cell lymphoma have changed,and the detection of peripheral blood lymphocyte subsets was of high value for the evaluation and diagnosis.Peripheral blood immune cell monitoring of patients could timely determine the immune status of patients in order to better guide the use of chemotherapy drugs.
		2021 Vol. 28 (14): 13-17 [Abstract] ( 48 ) HTML (50 KB) PDF (0 KB) ( 5 )

	18	Study on related factors of postoperative symptom aggravation in surgical treatment of myasthenia gravis
		ZHANG Yu-chen； HAO Meng-fu； ZHAGN Wen-qiang； HUANG Zhuang-shi
		Objective To explore the related factors of postoperative symptom aggravation in surgical treatment of myasthenia gravis(MG).Methods The clinical data of 128 patients with MG who underwent thymectomy in the Second Affiliated Hospital of Zhengzhou University from June 2013 to June 2019 were retrospectively analyzed.The preoperative and postoperative classifications of each patient were evaluated according to the surgical classification standard of MG,and patients were divided into the addition group and the stable group based on whether they were aggravated.The addition group:after surgery,the symptoms of MG patients were aggravated during the hospitalization(type increased),or the amount of medication requirement was increased.The stable group:after surgery,the symptoms of MG patients were relieved(type reduced)or unchanged(type unchanged)during the hospitalization,or the amount of medication needed to maintain current symptoms was reduced.Single factor and multivariate Logistic regression were used to analyze the related factors of postoperative symptoms aggravated.Results Of the 128 patients,40 cases were in the addition group,and 88 cases were in the stable group.There were statistically significant differences in the surgical methods,Osserman classification and pathological types of thymus between the two groups(P＜0.05).Logistic regression analysis showed that surgical methods,Osserman classification,and thymus pathological type were related factors affecting postoperative symptoms of MG patients(P＜0.05).In Osserman classification,compared with typeⅠMG patients,patients of typesⅡB andⅢhad a higher probability of postoperative aggravation of symptoms.Conclusion Thymectomy is the main surgical treatment for MG.The choice of surgical methods,Osserman classification and the pathological type of thymoma are related factors for the aggravation of symptoms in MG patients after surgical treatment.Choosing a reasonable surgical method,combined with the MG Osserman classification and the pathological type of the thymus,has guiding significance for the prevention of postoperative symptoms of MG.
		2021 Vol. 28 (14): 18-21转26 [Abstract] ( 37 ) HTML (39 KB) PDF (0 KB) ( 6 )

	22	Screening of protective agent formula for freezing and vacuum drying process of Streptococcus pneumoniae type 4 strain
		HAO Yi-nan； ZHANG Jing-jing； GUO Bing-feng； WANG Ming-hua； WANG Ya-ping； WANG Bin
		Objective To screen the formula of the protective agent for the freezing and vacuum drying process of Streptococcus pneumoniae type 4 strain through orthogonal experiments,and to analyze the activity,genetic stability and growth characteristics of the strains under the formula,and find the long-term and stable freeze-dried protective agent formulation.Methods Streptococcus pneumoniae type 4 strain was selected as the test strain.The survival rate of the strain before and after freeze-drying was used as an evaluation index.The freeze-dried protective agent formula was determined by using a three-factor orthogonal test.After freeze-drying,the activity,genetic stability and growth characteristics of the bacteria under the formula were analyzed.Results Through orthogonal experiment,the best freeze-drying protective agent formula was determined as:5% skimmed milk powder+10% trehalose+10% sodium glutamate.The concentration of the bacterial solution before lyophilization was 2.35×108 cfu/mL.After lyophilization,the strains were stored for different times(after lyophilization,storage 90,180,360 days)to test their activity,genetic stability,and growth characteristics.The activities were 81.2%,80.4%,80.1% and 79.8%.The homology analysis was 100%,and there was no difference in growth characteristics.This formulation compatible with types of 6A,18C and 19F Streptococcus pneumoniae also have good protection under the freeze-vacuum drying process,and the survival rate of the three batches of samples at day 0 was all above 78%.Conclusion After the optimization of the freeze-dried protective agent formulation,the survival rate and stability of the strains maintain a high level,and the formulation process can be used for freeze-vacuum drying and storage of different serotypes of Streptococcus pneumoniae,providing stable and reliable strains for the production of Streptococcus pneumoniae polysaccharide vaccines.
		2021 Vol. 28 (14): 22-26 [Abstract] ( 50 ) HTML (41 KB) PDF (0 KB) ( 6 )

	27	Diagnostic value of frozen lung biopsy under rigid bronchoscope for peripheral pulmonary nodules
		HUANG Rui ；YONG Ya-zhi ；ZENG Jun-li ；CHEN Zhi-de
		Objective To investigate the diagnostic rate and safety of frozen lung biopsy under rigid bronchoscope for peripheral pulmonary nodules.Methods A retrospective analysis was performed on 42 patients who received frozen lung biopsy under rigid bronchoscope of peripheral pulmonary nodules(8 mm＜maximum diameter of nodules≤30 mm)admitted to the Second Affiliated Hospital of Xiamen Medical University from November 2017 to February 2019.Patients were divided into group A(8 mm＜nodule diameter≤20 mm,n=18)and group B(20 mm＜nodule diameter≤30 mm,n=24)according to the size of nodule.All patients underwent frozen lung biopsy under rigid bronchoscope.The positive rate of malignant tumor and complications were compared between the two groups.Results The positive and negative rates of malignant tumors in group A were 55.5%(10/18)and 44.5%(8/18),respectively.The positive and negative rates of malignant tumors in group B were 87.5%(21/24)and 12.5%(3/24),respectively.The positive rate of malignant tumor diagnosis in group B was higher than that in group A,the difference was statistically significant(χ2=3.903,P=0.048).There was no significant difference in the incidence of bleeding and pneumothorax between the two groups(P＞0.05).Patients in both groups were discharged successfully after active treatment.Conclusion Frozen lung biopsy under rigid bronchoscope has a high positive rate for the diagnosis of peripheral pulmonary nodules,especially for patients with peripheral pulmonary nodules with nodule diameter＞20 mm to≤30 mm that the positive rate of malignant tumor diagnosis can reach 87.5%,and the incidence of bleeding and pneumothorax in patients with different nodule diameters is relatively low,which is safe.
		2021 Vol. 28 (14): 27-30 [Abstract] ( 44 ) HTML (37 KB) PDF (0 KB) ( 7 )

	31	Advances in the understanding of chronic obstructive pulmonary disease complicated with malnutrition
		ZHAO Zi-xin；LIU Hai-ying； LU Lin；SUN Lin-lin； LEI Xiao-hong
		Malnutrition is an increasing incidence in patients with chronic obstructive pulmonary disease(COPD).It has been proved that malnutrition will aggravate the progression of COPD,and in severe cases,pulmonary cachexia will appear,and even increase the mortality rate of the disease.Malnutrition can be regarded as an independent risk factor for poor prognosis in COPD patients,therefore,timely and effective diagnosis and intervention of nutritional status is an indispensable part of clinical work.In this research,the etiology and pathogenesis of COPD combined with malnutrition,the influence on the body,nutritional support and other aspects were elaborated,with a view to attracting great attention from clinical work,early detection of the risk of malnutrition in COPD patients,timely and appropriate nutritional support,to improve the quality of life of patients,it is of great theoretical and practical significance to reduce the risk of acute exacerbation in COPD patients and delay the progression of the disease.
		2021 Vol. 28 (14): 31-34 [Abstract] ( 43 ) HTML (39 KB) PDF (0 KB) ( 5 )

	35	Progress in application of mesenchymal stem cells in tissue engineering of tympanic membrane regeneration
		LYU Cui-ting； HU Yi； SHEN Yi
		Eardrum is an important structure of hearing conduction and a protective barrier of the middle ear.Perforation may causes hearing loss,otorrhea and even serious complications.Trauma,middle ear infection and tympanostomy are the main causes of tympanic membrane perforation.Otolaryngologists will close the perforated eardrum via a surgery intervention.However,due to the limitations of surgical technical requirements,high costs,and surgical complications,it is necessary to find out a better alternative to surgical methed.With respect to this issue,the tissue engineering has been applied in experimental and clinical studies,including the biocompatible scaffolds,growth factors and stem cells to restore and improve the function of the eardrum.Mesenchymal stem cells(MSCs)are progenitors that can differentiate into a variety of cell types,can be isolated from a variety of tissues,and facilitiy to be cultured in vitro.Due to its biological characteristics,MSCs have attracted much attention in the treatment of many diseases.Studies have shown that the application of MSCs alone or in combination with biomaterials at the site of tympanic membrane rupture may promote the migration and proliferation of keratinocytes and thereby promote the closure of perforated tympanic membrane.This paper reviews the application of MSCs in tympanic membrane regeneration and its potential mechanism,and discusses the existing problems in the application of MSCs.
		2021 Vol. 28 (14): 35-38转46 [Abstract] ( 58 ) HTML (40 KB) PDF (0 KB) ( 7 )

	39	Progress on research the relationship between food allergy and respiratory diseases in children
		LIU Xian；LUO Xue-mei； TANG Hong-ping
		The prevalence of food allergy in children is increasing year by year.Food allergy in children has become one of the main factors affecting children′s health,and has attracted wide attention.There is a close relationship between food allergy and respiratory diseases,and they have some similar pathogenesis.Food allergies in early childhood are risk factors for bronchial asthma,allergic rhinitis and other diseases in the future.Food allergy can not only induce respiratory diseases,but also co-exist and interact with each other to aggravate the disease.In severe cases,fatal allergic reactions can even occur,threatening the life of children.The purpose of this review is to summarize the epidemiology,pathogenesis and correlation of food allergy and respiratory diseases in children,and to elaborate the interrelation between them.
		2021 Vol. 28 (14): 39-42 [Abstract] ( 42 ) HTML (40 KB) PDF (0 KB) ( 6 )

	43	Relationship between serum IgG subtype levels of chronic obstructive pulmonary disease and acute exacerbation and hospitalization risk
		SHEN Pei-lei； SUN Pan-bo； LUO Bin
		Objective To analyze the relationship between serum immunoglobulin G(IgG)subtype levels of chronic obstructive pulmonary disease(COPD)and acute exacerbation and hospitalization risk.Methods A total of 60 patients with stable COPD in Shangrao Municipal Hospital of Jiangxi Province from June 2019 to February 2020 were selected as the observation group,according to the IgG4 level of the patients,19 COPD patients whose IgG4 level was lower than the normal level and accompanied with more than 2 acute attacks in 1 year were classified as the low group,41 COPD patients with normal IgG4 level were included in the normal group.In addition,20 patients who had no disease in this hospital during the same period were selected as the control group.The serum IgG4 level was compared between the observation group and control group,and the relationship between serum IgG4 level and acute exacerbation and hospitalization risk was analyzed.Results The IgG4 level of the observation group was lower than that of the control group,and the difference was statistically significant(P＜0.05).The frequency of acute exacerbation and the frequency of hospitalization in the low group before intervention were higher than those in the normal group,and the differences were statistically significant(P＜0.05).After intervention,there were no significant differences in the frequency of acute exacerbation and the frequency of hospitalization between the low group and the normal group(P＞0.05).Conclusion Low serum IgG subtype levels in patients with COPD will increase the frequency of acute exacerbation and the risk of hospitalization.The application of Thymalfasin can effectively reduce the number of acute exacerbations and the frequency of hospitalization in COPD patients with low IgG subtype levels.Therefore,the serum IgG subtype has a certain early warning effect on the acute onset of COPD.
		2021 Vol. 28 (14): 43-46 [Abstract] ( 47 ) HTML (35 KB) PDF (0 KB) ( 11 )

	47	Clinical study of early hyperbaric oxygen(HBO)therapy for wake-up promotion in comatose patients with severe craniocerebral injury
		ZHANG Qi ；YIN Xiu-ling； LUO Juan； ZHU Jiang-zhen
		Objective To investigate the clinical effect of early hyperbaric oxygen(HBO)therapy for wake-up promotion in comatose patients with severe craniocerebral injury.Methods A total of 120 cases of comatose patients with severe craniocerebral injury admitted to the First Affiliated Hospital of Nanchang University from January 2015 to December 2017 were selected as the research objects,and they were divided into the treatment group(n=60)and the control group(n=60)according to different treatment methods.The control group received traditional rehabilitation treatment for wake-up promotion,and on this basis,the treatment group was given HBO treatment(group A[n=10]:course≤10 days,HBO treatment 1-10 times;group B[n=10]:course≤10 days,HBO treatment 11-20 times;group C[n=10]:course≤10 days,HBO treatment 21-30 times;group D[n=10]:course 11-20 days,HBO treatment 1-10 times;group E[n=10]:course 11-20 days,HBO treatment 11-20 times;group F[n=10]:course 11-20 days,HBO treatment 21-30 times).The Glasgow coma scale(GCS)scores were compared in each group before treatment,at 10,20 and 30 days after treatment.Results There were no statistically significant differences in the GSC scores of each group before treatment and at 10 days after treatment(P＞0.05).The GSC scores of the experimental group were(9.62±2.68)and(12.48±2.01)points at 20 and 30 days after treatment,which were higher than the control group′s(7.39±2.14)and(8.05±1.45)points,the differences were statistically significant(P＜0.05).Among the patients with disease course≤10 d in the experimental group,the GSC scores in group C were(13.45±2.32)and(15.20±2.15)points at 20 and 30 days after treatment,which were higher than those in group B of(11.01±2.01)and(12.05±2.01)points,also higher than those in group A of(8.95±1.98)and(10.56±1.95)points,the differences were statistically significant(P＜0.05).Among patients with disease course from 11 to 20 days,the GSC scores of group F were(11.32±1.95)and(12.48±2.37)points at 20 and 30 days after treatment,which were higher than those of group E for(9.01±2.29)and(10.56±1.65)points,also higher than those of group D for(7.43±2.05)and(8.12±1.36)points,the differences were statistically significant(P＜0.05).For the same number of treatments in the experimental group,at 20 and 30 days after treatment,the GSC score of group A was higher than that of group D,the GSC score of group B was higher than that of group E,and the GSC score of group C was higher than that of group F,the differences were statistically significant(P＜0.05).Conclusion The wake-up promotion effect of early HBO in the treatment of comatose patients with severe craniocerebral injury is better,and the best time window for HBO treatment is within 10 days after the onset of the disease,and 21-30 times of treatment is appropriate.
		2021 Vol. 28 (14): 47-49转53 [Abstract] ( 53 ) HTML (31 KB) PDF (0 KB) ( 4 )

	50	Clinical effect of Thrombin Freeze-dried Powder combined with proton pump inhibitor in treatment of peptic ulcer hemorrhage
		HU Qing-fang
		Objective To investigate the clinical effect of Thrombin Freeze-dried Powder combined with proton pump inhibitor in treatment of peptic ulcer hemorrhage.Methods A total of 60 patients with peptic ulcer hemorrhage admitted to the First People′s Hospital of Ji′an City from January 2018 to January 2019 were selected as the research objects,and they were divided into the control group and the experimental group according to the method of dynamic random grouping,with 30 cases in each group.The control group was treated with proton pump inhibitor,and the experimental group was treated with Thrombin Freeze-dried Powder combined with proton pump inhibitor.The clinical efficacy,coagulation indexes,platelet parameters and adverse reactions were compared between the two groups.Results The total effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P＜0.05).There were no statistically significant differences in plasma prothrombin time(PT),international normalized ratio(INR),activated partial thromboplastin time(APTT),thrombin time(TT),fibrinogen content(Fg),platelet count(BPC),platelet specific volume(PCT)and mean blood platelet volume(MPV)between the two groups before treatment(P＞0.05).The PT,INR,APTT,TT,MPV of the two groups after treatment were lower than those before treatment,the FG,BPC and PCT of the two groups after treatment were higher than those before treatment,and the differences were statistically significant(P＜0.05).After treatment,the PT,INR,APTT,TT,MPV in the experimental group were lower than those in the control group,the Fg,BPC and PCT in the experimental group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in the experimental group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Thrombin freeze-dried powder combined with proton pump inhibitor has a significant effect treating peptic ulcer hemorrhage.
		2021 Vol. 28 (14): 50-53 [Abstract] ( 53 ) HTML (31 KB) PDF (0 KB) ( 6 )

	54	Clinical observation of retinopathy in patients with systemic lupus erythematosus complicated with antiphospholipid syndrome
		LIU Xiao-guang
		Objective To summarize and analyze the clinical manifestations,examination and treatment characteristics of retinopathy in patients with systemic lupus erythematosus(SLE)complicated with antiphospholipid syndrome(APS),so as to improve the diagnosis and treatment awareness of clinists and improve the prognosis.Methods A retrospective analysis of the clinical data of 11 patients with retinopathy of SLE and APS admitted to the Department of Rheumatology and Ophthalmology of the First Hospital of Lanzhou University from July 2013 to November 2020.Results Among the 11 patients,there were 2 males and 9 females.The average age was(28.4±10.1)years from 15 to 54 years old.The course of SLE ranged from 0.1 to 320.0 months,with an average of(50.9±43.4)months.SLE related clinical manifestations included skin erythema in 5 cases,arthralgia in 4 cases,fever in 3 cases,Raynault′s phenomenon in 3 cases,oral ulcer in 4 cases,and polyserositis in 2 cases.The organ damage of SLE:renal damage in 6 cases,nervous system damage in 4 cases,blood system damage in 7 cases,and venous thrombosis in lower limbs in 1 case.Retinal waffle plaques were found in 12 eyes,central retinal vein occlusion(CRVO)in 2 eyes,branch retinal vein occlusion(BRVO)in 2 eyes,retinal neovascularization in 6 eyes,retinal hemorrhage in 6 eyes,and optic nerve atrophy in 2 eyes.Laboratory examination:11 cases were positive for ANA,8 for anti-DS-DNA,11 for ACL,10 for β2-GP1,4 for RNP,5 for Sm,3 for RRNP,and 7 for SSA.IgG increased in 9 cases,complement C3 decreased in 8 cases,C-reaction protein(CRP)increased in 9 cases,and erythrocyte sedimentation rate increased in 10 cases.SLE disease activity index(SLEDAI)score ranged from 4 to 25 points,with an average score of(14.5±5.0)points,including 7 patients with severe activity,2 patients with moderate activity,and 2 patients with mild activity.All patients in this group were treated with glucocorticoid,immunosuppressant and antiplatelet aggregation therapy,and some patients were treated with anticoagulation,ophthalmic laser and intravitreal injection of Rayzumab/Compacsep.After treatment,visual acuity of 8 patients was improved to varying degrees,and visual acuity of 3 patients was not improved.Conclusion SLE combined with APS retinopathy has a serious impact on the vision of patients,and some patients are the first symptoms,patients with SLE combined with APS should undergo routine fundus examination.Glucocorticoid,immunosuppressant and anticoagulant therapy were effective in some patients,but the prognosis of CRVO and CRAO patients was very poor.
		2021 Vol. 28 (14): 54-57 [Abstract] ( 35 ) HTML (35 KB) PDF (0 KB) ( 8 )

	58	Clinical effect of intestinal function training combined with defecation training to intervene in patients after cerebral hemorrhage
		WU Chun-yan
		Objective To investigate the clinical effect of intestinal function training combined with defecation training to intervene in patients after cerebral hemorrhage.Methods A total of 69 postoperative cerebral hemorrhage patients in the Second People′s Hospital of Jingdezhen from September 2018 to December 2019 were selected as the research subjects.They were divided into the routine group(n=34)and the training group(n=35)by the random number table method.The routine group received routine interventions in neurology,and patients in the training group received intestinal function training and defecation training on the basis of the routine group.The clinical intervention effect,the severity of constipation,the use of laxatives or enema,and the quality of life of the two groups were compared.Results After 2 weeks of intervention,the clinical intervention effect of the training group was better than that of the conventional group,the difference was statistically significant(P＜0.05),and the severity of constipation was lighter than that of the conventional group,the difference was statistically significant(P＜0.05).The utilization rates of laxative and enema in the training group were lower than those in the conventional group,and the differences were statistically significant(P＜0.05).After intervention,patient assessment of constipation quality of life questionnaire(PAC-QOL)scores of constipation patients in both groups were lower than those before intervention,with statistical significance(P＜0.05).The PAC-QOL score of the training group was lower than that of the conventional group,and the difference was statistically significant(P＜0.05).Conclusion The combination of intestinal function training and defecation training in patients after cerebral hemorrhage can reduce the severity of constipation,reduce the use of laxatives and enema,ameliorate the quality of life,and improve the effect of intervention.
		2021 Vol. 28 (14): 58-60转64 [Abstract] ( 43 ) HTML (33 KB) PDF (0 KB) ( 6 )

	61	Effect of continuous bedside blood purification in the treatment of severe acute pancreatitis
		HUANG Hai-ping； HE Xiao-yan； CHEN Zhi-peng； LIU Yong
		Objective To investigate the effect of continuous bedside blood purification in the treatment of severe acute pancreatitis.Methods A total of 50 patients with severe acute pancreatitis in Zhangzhou Affiliated Hospital of Fujian Medical University from June 2014 to June 2018 were selected as the research objects,and they were divided into the observation group(n=25)and the control group(n=25)by the random number table method.Patients in the control group were treated with conventional treatment methods,and patients in the observation group were treated with continuous bedside blood purification on this basis.The clinical symptom relief,hospitalization time,inflammatory factor levels,acute physiology and chronic health score(APACHEⅡscore)and survival rate of patients between the two groups were observed.Results The abdominal pain disappearance time,abdominal distension remission time and hospitalization time of the observation group were shorter than those of the control group,the differences were statistically significant(P＜0.05).After treatment,the four indexes of interleukin-1,interleukin-6,interleukin-8 and tumor necrosis factor of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).After treatment,the four inflammatory factor indexes of the two groups were lower than those before treatment,and the differences were statistically significant(P＜0.05).After treatment,the APACHEⅡscore of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).After treatment,the APACHEⅡscores of the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05).The survival rate in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).Conclusion For patients with severe acute pancreatitis,continuous bedside blood purification can effectively relieve the clinical symptoms and reduce the death cases,which is worthy of clinical promotion.
		2021 Vol. 28 (14): 61-64 [Abstract] ( 45 ) HTML (34 KB) PDF (0 KB) ( 6 )

	65	Clinical effect of sclerotherapy with different administration methods of lauromacrogol under colonoscopy assisted by transparent cap in the treatment of stage I andⅡhemorrhagic internal hemorrhoids
		QIN Guo-tao； YANG Li；DAI Chun-lei； MA Wei-yan；WANG Zhong-hui； YANG Liu；LIU Zhi-zhong
		Objective To evaluate the efficacy and safety of sclerotherapy with different administration methods of lauromacrogol under transparent cap assisted colonoscopy in the treatment of stage I andⅡhemorrhagic internal hemorrhoids.Methods A total of 130 patients with stageⅠandⅡhemorrhagic internal hemorrhoids were selected as subjects from January 2019 to January 2020 in the Department of Gastroenterology in the General Hospital of China First Automobile Works Group,Jilin Province.The patients were divided into control group(75 cases)and observation group(55 cases)according to the order of admission time.The patients in the control group were divided into control group 1(stageⅠ,42 cases)and control group 2(stageⅡ,33 cases).The patients in the observation group were divided into observation group 1(stageⅠ,32 cases)and observation group 2(stageⅡ,23 cases).The control group 1 and control group 2 were treated with lauryl alcohol liquid sclerotherapy under colonoscopy assisted by transparent cap.The observation group 1 and the observation group 2 were treated with lauromacrogol foam sclerotherapy under colonoscopy assisted by transparent cap.The total dosage of lauryl alcohol,the total effective rate and the incidence of complications were compared.Results There was no significant difference in the total amount of lauromacrogol between the observation group 1 and the observation group 2(P＞0.05).The total amount of lauromacrogol in observation group 1 was less than control group 1,and the difference was statistically significant(P＜0.05).The total amount of lauromacrogol in observation group 2 was less than control group 2,and the difference was statistically significant(P＜0.05).There was no significant difference in the total effective rate between the observation group 1 and the control group 1(P＞0.05).There was no significant difference in the total effective rate between the observation group and the control group(P＞0.05).The total incidence of postoperative complications in observation group 1 was lower than control group 1,and the difference was statistically significant(P＜0.05).The total incidence of postoperative complications in observation group 2 was lower than control group 2,and the difference was statistically significant(P＜0.05).Conclusion Under colonoscopy assisted by transparent cap,the injection of lauromacrogol sclerosis agent is safe and effective in the treatment of stage I andⅡhemorrhagic internal hemorrhoids.Compared with liquid administration,foam administration of lauromacrogol has less dose and lower complication rate,which has obvious advantages.
		2021 Vol. 28 (14): 65-68 [Abstract] ( 44 ) HTML (35 KB) PDF (0 KB) ( 7 )

	69	Effect of alveolar lavage on blood gas analysis and serum inflammatory indexes in emergency patients with severe pneumonia with respiratory failure
		LI Ji-hua；CHENG Zong-kai
		Objective To investigate the effect of alveolar lavage on blood gas analysis and serum inflammatory indexes in patients with severe pneumonia complicated with respiratory failure.Methods A total of 68 patients with severe pneumonia complicated with respiratory failure who were treated in the Emergency Department of Nanchang Hongdu Hospital of Traditional Chinese Medicine from January 1,2017 to January 1,2020 were selected and divided into the observation group(35 cases)and the control group(33 cases)according to the random number table method.The control group was given conventional treatment,and the observation group was given bronchoalveolar lavage on the basis of conventional treatment.After 3 days of treatment,the clinical efficacy,severity of the disease,blood gas analysis and serum inflammatory indexes of the two groups were compared.Results After treatment,the total effective rate of the observation group(97.14%)was higher than that of the control group(66.67%),and the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in acute physiology and chronic health(APACHEⅡ)score between the two groups(P＞0.05).After treatment,APACHEⅡscores of the two groups were lower than those before treatment,and the differences were statistically significant(P＜0.05).After treatment,APACHEⅡscore of the observation group was lower than that of the control group,and the difference was statistically significant(P＜0.05).Before treatment,there were no statistically significant differences in arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2)between the two groups(P＞0.05).After treatment,the PaO2 levels of the two groups were higher than those before treatment,the PaCO2 levels of the two groups were lower than those before treatment,and the differences were statistically significant(P＜0.05).After treatment,the PaO2 of the observation group was higher than that of the control group,PaCO2 of the observation group was lower than that of the control group,and the differences were statistically significant(P＜0.05).Before treatment,there were no statistically significant differences in the levels of serum C-reactive protein(CRP),procalcitonin(PCT)between the two groups(P＞0.05).After treatment,the levels of CRP and PCT in the two groups were lower than those before treatment,and the differences were statistically significant(P＜0.05).After treatment,the levels of CRP and PCT in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion The curative effect of bronchoalveolar lavage in emergency patients with severe pneumonia complicated with respiratory failure is exact,which can effectively reduce the symptoms of respiratory failure,inhibit the inflammatory reaction of the body and significantly alleviate the condition,which has high clinical application value.
		2021 Vol. 28 (14): 69-72转76 [Abstract] ( 47 ) HTML (39 KB) PDF (0 KB) ( 8 )

	73	Effect of non-invasive ventilator in the treatment of chronic obstructive pulmonary disease complicated with respiratory failure and its influence on lung function
		WU Nan
		Objective To analyze the effect of non-invasive ventilator in the treatment of chronic obstructive pulmonary disease complicated with respiratory failure and its effect on lung function.Methods A total of 100 patients with chronic obstructive pulmonary disease complicated with respiratory failure admitted to Jinzhou Central Hospital from June 2015 to February 2018 were selected for this study.They were divided into control group and observation group by random number table method,with 50 patients in each group.The control group was treated with conventional treatment,while the observation group was treated with non-invasive ventilator in addition to conventional treatment.The total effective rate,pulmonary function indexes and complications were compared between the two groups.Results After treatment,the total effective rate,forced expiratory volume in the first second(FEV1),forced expiratory volume in the first second(FVC)and the ratio of forced expiratory volume in the first second to forced expiratory volume(FEV1/FVC)in the observation group were higher than those in the control group,and the total incidence of complications in the observation group was lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Non-invasive ventilator therapy is effective in patients with chronic obstructive pulmonary disease complicated with respiratory failure,which can improve lung function,reduce complications,and promote the improvement of respiratory function,which has positive clinical significance.
		2021 Vol. 28 (14): 73-76 [Abstract] ( 42 ) HTML (33 KB) PDF (0 KB) ( 7 )

	77	Effect and safety of autologous platelet-rich gel in the treatment of elderly diabetic foot ulcers combined with lower extremity atherosclerotic disease
		QIU Zi-jin； LIU Fang；LI Yong2 WU Yu-chen； ZHANG Shi-yin；CHEN De-qing
		Objective To explore the effect and safety of autologous platelet-rich gel in the treatment of elderly diabetic foot ulcers combined with lower extremity atherosclerotic disease.Methods A total of 120 elderly patients with diabetic foot ulcer combined with lower extremity atherosclerotic disease admitted to Chongqing Hospital of Traditional Chinese Medicine from November 2015 to September 2020 as the research objects and divided into the experimental group(61 cases)and the control group(59 cases)according to the random number table method.The control group was treated with conventional methods,and the experimental group was treated with autologous platelet-rich gel on the basis of conventional treatments.The ulcer area,redness and swelling area,ulcer depth,local pain score,time of new epithelium appeared,satisfaction score,and total effectiveness were compared between two groups.Results After treatment,the ulcer area,redness and swelling area,and ulcer depth of the experimental group were smaller than those of the control group,the local pain score in the experimental group was lower than that in the control group,the time of new epithelium appeared in the experimental group was shorter than that in the control group,the satisfaction and total effectiveness of treatment of the experimental group were higher than those of the control group,and the differences were statistically significant(P＜0.05).There were no obvious adverse reactions in both groups.Conclusion Autologous platelet-rich gel treats elderly diabetic foot ulcers with lower extremity atherosclerotic disease,could effectively promote wound healing and reduce pain,the curative effect is accurate,safe and reliable.Which is worth further popularizing and using in clinic.
		2021 Vol. 28 (14): 77-80 [Abstract] ( 45 ) HTML (40 KB) PDF (0 KB) ( 4 )

	81	Analysis of risk factors of diabetic patients with neck abscess
		LI Dong-mei； HUANG Bai-feng； ZHANG Mei-yan； ZHOU Xia
		Objective To explore the risk factors of diabetic patients with neck abscess.Methods A retrospective analysis of the clinical data of 220 diabetic patients admitted to Xiaolan People′s Hospital of Zhongshan City from January 2014 to September 2020,48 patients with neck abscess were set up as observation group,and 172 patients without neck abscess were set up as control group.The sex,age,diabetes course,personal hygiene,fasting plasma glucose(FPG),hemoglobin A1c(HbA1c),smoking,alcohol consumption,education level and nuclear factors of family economic condition were compared between two groups,and Logistic regression model was used to analyze the independent risk factors of diabetic patients with neck abscess.Results The results of univariate analysis showed that diabetic patients with neck abscess were associated with age,personal hygiene,diabetes course,FPG level and HbA1c level(P＜0.05).A multivariate analysis Logistic the regression model showed that the age≥60 years(β=1.792,OR=2.089,95%CI=1.168-3.537),personal hygiene in general(β=1.615,OR=2.742,95%CI=1.496-4.875),FPG≥10.0 mmol/L(β=1.488,OR=4.925,95%CI=2.630-9.964）,and HbA1c≥6.5%(β=1.527,OR=3.367,95%CI=2.072-5.528)were independent risk factors(P＜0.05).Conclusion There are many factors that cause diabetes complicated with neck abscess,including age,general personal hygiene and hyperglycemia.The clinical should focus on these patients and take targeted nursing measures to prevent it.
		2021 Vol. 28 (14): 81-83转88 [Abstract] ( 38 ) HTML (30 KB) PDF (0 KB) ( 6 )

	84	Clinical observation of Empagliflozin in the treatment of type 2 diabetic nephropathy
		LIU Hong-dan； FAN Jing
		Objective To observe the clinical efficacy of Empagliflozin in the treatment of early type 2 diabetic nephropathy.Methods A total of 40 patients with type 2 diabetic nephropathy admitted to Fangshan District First Hospital of Beijing from December 2018 to February 2020 were selected as the research objects,and divided into the control group(20 cases)and the study group(20 cases)according to the random number table method.On the basis of the original hypoglycemic agents,renin angiotensin system blockers and the statins,the control group was treated with Siglitazine,and the study group was treated with Empagliflozin,both groups were treated for 24 weeks.Fasting plasma glucose(FPG),2 hours postprandial blood glucose(2 h PBG),glycosylated hemoglobin(HbA1c),blood lipid(including triacylglycerol[TG],total cholesterol[TC],high density lipoprotein cholesterol[HDL-C],low density lipoprotein cholesterol[LDL-C]),uric acid(UA),body mass index(BMI),blood pressure(including systolic pressure[SBP]and diastolic pressure[DBP]),albumin-to-creatinine ratio(ACR)and estimated glomerular filtration rate(eGFR)were compared between the two groups,and adverse reactions were recorded.Results After treatment,the levels of FPG,2 h PG and HbA1c in the two groups were lower than those before treatment,and the differences were statistically significant(P＜0.01).After treatment,there was no significant difference in the levels of FPG,2 h PG,HbA1c between the study group and the control group(P＞0.05).After treatment,the TG levels of the two groups were lower than those before treatment,and the TG level of the study group was lower than that of the control group,the differences were statistically significant(P＜0.05).The HDL-C levels of the two groups were higher than those before treatment,and the HDL-C level of the study group was higher than that of the control group,the differences were statistically significant(P＜0.05).Before and after treatment,there were no significant difference of the TC and LDL-C levels between the two groups(P＞0.05).After treatment,the levels of UA,BMI,SBP,DBP,ACR in the two groups were lower than those before treatment,and the levels of UA,BMI,SBP,DBP,ACR in the study group was lower than that in the control group,the differences were statistically significant(P＜0.05).Before and after treatment,there was no significant difference of the eGFR level between the two groups(P＞0.05).There was no obvious adverse reaction in both groups.Conclusion Empagliflozin treatment of early type 2 diabetic nephropathy can effectively reduce urinary protein excretion,delay the progression of diabetic nephropathy,and good safety,which is worthy of clinical application.
		2021 Vol. 28 (14): 84-88 [Abstract] ( 65 ) HTML (36 KB) PDF (0 KB) ( 9 )

	89	Study on the correlation between metabolic syndrome and cardiovascular and cerebrovascular diseases
		KONG Li； LI Jie
		Objective To investigate the relationship between metabolic syndrome and cardiovascular and cerebrovascular diseases.Methods A total of 86 patients with metabolic syndrome admitted to 96604 Army Hospital of the Chinese People′s Liberation Army from May 2018 to February 2020 and 216 patients with metabolic syndrome found during physical examination in same hospital from January 2016 to February 2018 were selected as the research subjects.They were divided into a control group(n=74)and an observation group(n=228)according to whether combined with cardiovascular and cerebrovascular diseases.In the control group,there was no case of cardiovascular and cerebrovascular diseases,and in the observation group,cases were complicated with cardiovascular and cerebrovascular diseases.The examination results of the two groups were compared,and the patient′s carotid artery plaque formation was analyzed.Results The triglyceride(TG),low density lipoprotein-cholesterol(LDL-C),homeostasis model assessment of insulin resistance(HOMA-IR),TG/HDL-C,LDL-C/high density lipoprotein cholesterol(HDL-C)and waist circumference indexes in the observation group were higher than those in the control group,the HDL-C index in the observation group was lower than that of the control group,and the differences were statistically significant(P＜0.05).Comparing the detection rates of different diseases,the detection rates of hypertension,hyperglycemia and carotid atherosclerosis in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Metabolic syndrome is related to the cardiovascular and cerebrovascular diseases to a certain degree.It is an important measure to prevent cardiovascular and cerebrovascular diseases by effectively improving the levels of blood glucose and blood lipids and increasing the detection rate.
		2021 Vol. 28 (14): 89-91 [Abstract] ( 45 ) HTML (29 KB) PDF (0 KB) ( 7 )

	92	Effect analysis of the pericardial exfoliation on chronic constrictive pericarditis
		YAN Jin-jin； WU Hai ；HAN Bin-de
		Objective To explore the effect of pericardial exfoliation on chronic constrictive pericarditis.Methods A total of 60 patients with chronic constrictive pericarditis admitted to Jiangxi Chest Hospital from January 2018 to June 2020 were selected as the research objects,and divided into the observation group and the control group according to random number table method,with 30 cases in each group.The control group was treated with conservative drugs,and the observation group was treated with pericardial exfoliation.The clinical efficacy and cardiac function indexes of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).Left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD)and left ventricular end-systolic diameter(LVESD)in the observation group were lower than those in the control group,left ventricular fractional shortening(LVFS)in the observation group was higher than that in the control group,and the differences were statistically significant(P＜0.05).Conclusion The treatment of chronic constrictive pericarditis by pericardial exfoliation can improve the clinical symptoms and promote the return of cardiac function to normal.
		2021 Vol. 28 (14): 92-94 [Abstract] ( 46 ) HTML (29 KB) PDF (0 KB) ( 7 )

	95	Analysis of the risk factors of contralateral central lymph node metastasis in unilateral papillary thyroid carcinoma
		MU De-wu； CHEN Mao-shan； FAN Li；DU Song-li； YANG Hong-wei
		Objective To explore the risk factors of contralateral central lymph nodes(Cont-CLNs)metastasis in unilateral papillary thyroid carcinoma(uPTC).Methods The clinical data were collected from the uPTC patients who had underwent total thyroidectomy and bilateral central lymphadenectomy in Suining City Central Hospital from January 2014 to August 2020,and were analyzed retrospectively.And the risk factors related to Cont-CLNs were analyzed.Results A total of 119 eligible patients were collected,the rate of Cont-CLNs metastasis was 26.89%(32/119).The univariate analysis showed that Cont-CLNs metastasis was related to the Ipsi-CLNs metastasis,gender,diseased glandular lobe,tumor size,the distance between the lower edge of tumor and the lower edge of thyroid and Hashimoto's thyroiditis(P＜0.05).The result of Logistic regression model revealed that Ipsi-CLNs metastasis，the distance between the lower edge of tumor and the lower edge of thyroid≤10 mm and male were independent risk factors of Cont-CLNs metastasis(P＜0.05).Conclusion Cont-CLNs dissection should be considered when unilateral thyroid papillary carcinoma is associated with high-risk features such as Ipsi-CLNs metastasis,the distance between the lower edge of tumor and the lower edge of thyroid≤10 mm and male.
		2021 Vol. 28 (14): 95-98转102 [Abstract] ( 44 ) HTML (36 KB) PDF (0 KB) ( 6 )

	99	Effect of laparoscopic microwave ablation combined with hepatic lobectomy in the treatment of liver cancer
		WU Hua-fei
		Objective To explore the clinical effect of laparoscopic microwave ablation combined with hepatectomy in the treatment of liver cancer.Methods Retrospective analysis of 56 liver cancer patients admitted to the Fourth People′s Hospital of Chenzhou from March 2018 to June 2020.According to different treatment methods,they were divided into 28 cases in a simple operation group and 28 cases in a microwave ablation combined operation group.Among them,the simple operation group underwent laparoscopy.Hepatic lobectomy,microwave ablation combined with surgery group was treated with laparoscopic microwave ablation combined with hepatic lobectomy,liver function(alanine aminotransferase[ALT],aspartate aminotransferase[AST])levels were compared between the two groups before and after treatment,and the two groups were compared.The amount of bleeding,the operation time and the total incidence of postoperative complications.Results Before treatment,there were no significant difference in ALT and AST levels between the two groups of patients(P＞0.05).After treatment,the ALT and AST levels of the two groups were lower than before treatment,and the ALT and AST levels of the microwave ablation combined surgery group was lower than that of the surgery-only group,the differences were statistically significant(P＜0.05).The total incidence of postoperative complications in the microwave ablation combined surgery group was lower than that in the surgery alone group,and the difference was statistically significant(P＜0.05).The amount of blood loss of the microwave ablation combined surgery group was less than that of the surgery alone group,and the difference was statistically significant(P＜0.05).The operation time of the microwave ablation combined surgery group was shorter than that of the surgery alone group,and the difference was statistically significant(P＜0.05).Conclusion Laparoscopic microwave ablation combined with lobectomy can improve liver function,reduce intraoperative bleeding,shorten operation time and reduce the incidence of complications,which is worthy of promotion and application.
		2021 Vol. 28 (14): 99-102 [Abstract] ( 47 ) HTML (32 KB) PDF (0 KB) ( 5 )

	103	Effect of rapid rehabilitation surgery concept for postoperative rehabilitation in patients with laparoscopic radical gastrectomy
		WANG Hong-wei ；XIN Le； TANG Ming-sheng； LIU Yu ；YAN Yu-kuang
		Objective To explore the effect of rapid rehabilitation surgery concept for postoperative rehabilitation in patients with laparoscopic radical gastrectomy.Methods A total of 60 patients with laparoscopic radical gastrectomy admitted to Shenzhen Longgang Central Hospital from May 2018 to June 2019 as the research objects,and divided into the experimental group and the control group according to the random lottery method,with 30 cases in each group.The control group was given routine nursing,and the experimental group was given rapid rehabilitation surgery concept intervention on the basis of the control group.The postoperative rehabilitation effect,hospitalization time,medical expenses,total incidence of complications,rehospitalization rate and survival rate were compared between the two groups.Results The first defecation time,gastric tube placement time and anal exhaust recovery time in the experimental group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The hospitalization time of the experimental group was shorter than that of the control group,and the hospitalization cost of the experimental group was lower than that of the control group,the differences were statistically significant(P＜0.05).After 6 and 12 months of surgery,the incidence of complications and rehospitalization rate in the experimental group were lower than those in the control group,and the survival rate was higher than that in the control group,the differences were statistically significant(P＜0.05).Conclusion The application of rapid rehabilitation surgery concept in postoperative rehabilitation nursing of patients with laparoscopic radical gastrectomy for gastric cancer which can not only improve the rehabilitation effect,reduce medical expenses,but also effectively prevent the complications,which is worth promoting and applying.
		2021 Vol. 28 (14): 103-106 [Abstract] ( 39 ) HTML (36 KB) PDF (0 KB) ( 6 )

	107	Effects of Compound Guaiacol Potassium Sulfonate Oral Solution on acute bronchitis in children
		LIU Jia
		Objective To investigate the effect of Compound Guaiacol Potassium Sulfonate Oral Solution on children with acute bronchitis.Methods A total of 84 children with acute bronchitis treated in the Third People′s Hospital of Jingzhou City from January 2019 to January 2020 were selected as the research subjects.According to random number table method,they were divided into control group and observation group,with 42 cases in each group.The control group was given Ribavirin Injection intravenously,and the observation group was given Compound Guaiacol Potassium Sulfonate Oral Solution on this basis.After 10 d of treatment,the differences in efficacy,time of disappearance of clinical symptoms and incidence of adverse drug reactions,as well as the differences in serum inflammatory indexes(C-reactive protein[CRP],interlenkin-6[IL-6]and tumor necrosis factor[TNF]-α)between the two groups before and after 10 d of treatment were compared.Results After 10 d of treatment,the efficacy in the observation group was better than that in control group,and the total clinical effective rate was higher than that in the control group,and the differences were statistically significant(P＜0.05).The disappearance times of cough,high fever,expectoration and lung rales in the observation group were shorter than those in control group(P＜0.05).There was no significant difference in the total incidence rate of adverse drug reactions of gastrointestinal reactions,dizziness and somnolence between the two groups(P＞0.05).Before treatment,there were no significant differences in serum CRP,IL-6 and TNF-α between the two groups(P＞0.05).After 10 d of treatment,CRP,IL-6 and TNF-α in the two groups were lower than those before treatment,and serum CRP,IL-6 and TNF-α in observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Compound Guaiacol Potassium Sulfonate Oral Solution in the adjuvant treatment of children with acute bronchitis is safe,reliable and effective in accelerating the disappearance of clinical symptoms and improving the related indicators of inflammatory factors,which has clinical application value.
		2021 Vol. 28 (14): 107-109转113 [Abstract] ( 44 ) HTML (32 KB) PDF (0 KB) ( 6 )

	110	Research on the value of Conjugated Estrogen Cream combined with Misoprostol in ring removal after menopause
		ZHOU Juan-juan
		Objective To analyze the value of Conjugated Estrogen Cream combined with Misoprostol in ring removal after menopause.Methods A total of 80 postmenopausal patients who were treated in Xishan People′s Hospital from January 2017 to January 2020 were divided into control group(n=40)and observation group(n=40)according to random number table method.The control group were given Misoprostol 400 μg anal plug 1 h before operation,and the observation group was given 1 g of Conjugated Estregen Cream for vaginal medication for 1 week every day,and Misoprostol 400 μg anal plug 1 hour before operation.The visual analogue scores of the intraoperative dilation process,intraoperative blood loss,time of ring removal,total effective rate of cervical dilation,success rate of ring removal,and adverse reactions were compared between the two groups.Results The visual simulation score of intraoperative dilation of the observation group was lower than that of the control group,the amount of intraoperative blood loss was less than that of the control group,and the ring removal time was shorter than that of the control group,the differences were statistically significant(P＜0.05).The total effective rate of cervical dilation and the success rate of ring removal were higher than those of the control group,the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Conjugated Estrogen Cream combined with Misoprostol has a high value in the application of postmenopausal ring removal.Conjugated Estrogen Cream is simple and convenient for vaginal administration,and the amount of Estrogen is small.It can effectively dilate the cervix,shorten the time of ring removal,reduce bleeding and improve the success rate of ring removal,and alleviate the pain of patients,which is worthy of promotion.
		2021 Vol. 28 (14): 110-113 [Abstract] ( 47 ) HTML (33 KB) PDF (0 KB) ( 7 )

	114	Effect of Bakri balloon tamponade on postpartum hemoporrhage in elderly parturients
		ZHU Li-jun； JIANG Yuan-hong； HE Chuan-xiang
		Objective To investigate the effect of Bakri balloon tamponade on postpartum hemoporrhage in elderly parturients.Methods A total of 128 elderly parturients with postpartum hemorrhage who were admitted to Yichang Central People′s Hospital from January 2016 to December 2019 were selected as the research subjects.According to random number table,they were divided into observation group(64 cases)and control group(64 cases).The observation group was treated with Bakri balloon tamponade,while the control group was treated with B-Lynch suture.Operation time,postoperative blood loss,postoperative hemoglobin 24 h,hospitalization time,incidence of postpartum infection,incidence of uterine involution and success rate of hemostasis were compared between the two groups.Results The operation time,hospitalization time in the observation group were shorter than those of the control group and postoperative blood loss in the observation group was less than that in the control group,and the hemoglobin at 24 h after operation was higher than that in the control group,the differences were statistically significant(P＜0.05).There were no significant differences in the incidence of postpartum infection and uterine involution between the two groups(P＞0.05).The success rate of hemostasis in observation group was higher than that in control group,the difference was statistically significant(P＜0.05).Conclusion Bakri balloon tamponade has a good prevention and treatment effect on postpartum hemorrhage of elderly women,which is helpful to reduce the amount of postpartum hemorrhage and hospital stay,improve the success rate of hemostasis,and has high application safety,which is worthy of wide popularization and application.
		2021 Vol. 28 (14): 114-116转120 [Abstract] ( 38 ) HTML (32 KB) PDF (0 KB) ( 6 )

	117	Effect of oxytocin on induced labor in pregnant women with premature rupture of membranes during full-term pregnancy
		YU Hua
		Objective To analyze the effect of oxytocin on induced labor in pregnant women with premature rupture of membranes during full-term pregnancy.Methods A total of 82 pregnant women with premature rupture of membranes during full-term pregnancy admitted to the Department of Obstetrics and Gynecology of Maternal and Child Health Hospital of Jinpu New District from October 2018 to August 2020 were selected as the research subjects,and were divided into the control group(41 cases)and the observation group(41 cases)by the random number table method.The pregnant women in the control group were treated with intravenous drops of oxytocin for labor induction,and the pregnant women in the observation group were treated with small doses of oxytocin injection at acupoints for labor induction.The incidences of complications,oxytocin use in pregnant women,cervical score,postpartum blood loss,total length of labor,Apgar score and neonatal weight were compared between the two groups.Results The incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The duration of oxytocin instillation and the total labor duration in the observation group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The oxytocin instillation amount in the observation group was less than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in postpartum blood loss between the two groups(P＞0.05).The cervical score of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).The Apgar score in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in neonatal weight between the two groups(P＜0.05).Conclusion Low dose acupoint injection of oxytocin in pregnant women with full-term premature rupture of membrane for labor induction can reduce the usage of oxytocin,reduce the occurrence of complications in pregnant women and fetus,and has a significant effect on improving Apgar score of newborn infants,which is worthy of clinical promotion and application.
		2021 Vol. 28 (14): 117-120 [Abstract] ( 43 ) HTML (32 KB) PDF (0 KB) ( 7 )

	121	Effect of Kuntai combined with Letrozole and Chorionic Gonadotropin in the treatment of infertility
		CHEN Ling-yan
		Objective To explore the effect of Kuntai combined with Letrozole and Chorionic Gonadotropin in the treatment of infertility.Methods A total of 94 infertility patients who were treated in the Fuqing Maternity and Child Health Hospital from June 2018 to June 2019 were selected as study subjects.The patients were divided into control and study groups using the random number table method,with 47 patients in each group.The control group was treated with Letrozole and Chorionic Gonadotropin,and the study group was combined with Kuntai capsule.Clinical indicators,sex hormone levels before and after treatment,ovulation rate and pregnancy rate were compared between the two groups.Results After treatment,the level of estradiol(E2)in the study group was higher than that in the control group,while the levels of follicle stimulating hormone(FSH),luteinizing hormone(LH)and testosterone(T)were lower than those in the control group,the differences were statistically significant(P＜0.05).The mature days of follicles in the study group was shorter than that in the control group,and the thickness of endometrium,the number of mature follicles and the diameter of mature follicles were all larger than those in the control group,the differences were statistically significant(P＜0.05).The ovulation rate and pregnancy rate in the study group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Kuntai combined with Letrozole and Chorionic Gonadotropin are effective in the treatment of infertility,increase ovulation rate,pregnancy rate,and significantly improve sex hormone indicators,so it is worth recommending.
		2021 Vol. 28 (14): 121-123 [Abstract] ( 42 ) HTML (29 KB) PDF (0 KB) ( 6 )

	124	Effect of balloon compression combined with Oxytocin for cervical ripening and labor induction and its influence on maternal and infant outcome
		ZHONG Hua-dan； YAN Bin； WEI Qing-wen
		Objective To explore the effect of balloon compression combined with oxytocin for cervical ripening and labor induction,and its influence on maternal and infant outcomes.Methods A total of 88 parturients who were admitted to Dongguan Kanghua Hospital from August 2019 to August 2020 were selected as the research subjects.According to the random number table method,they were divided into control group and observation group,with 44 cases in each group.The control group was induced by Oxytocin,while the observation group was induced by balloon compression on the basis of the control group.The cervical maturity,labor time,labor process,induced labor outcome and maternal and infant outcome were compared between the two groups after intervention.Results The total effective rate of cervical maturity in observation group was higher than that in control group,the difference was statistically significant(P＜0.05).The labor time of observation group was shorter than that of control group,and the difference was statistically significant(P＜0.05).The first stage of labor,the second stage of labor,and the third stage of labor in the observation group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The vaginal delivery rate in the observation group was higher than that in the control group,and the cesarean section rate was lower than that in the control group,and the differences were statistically significant(P＜0.05).The total incidence of adverse maternal and infant outcomes in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Balloon compression combining with Oxytocin has a significant effect on cervical maturation,which can increasing the rate of vaginal delivery,reducing the rate of cesarean section,and improving the maternal and infant outcomes.
		2021 Vol. 28 (14): 124-126 [Abstract] ( 45 ) HTML (30 KB) PDF (0 KB) ( 7 )

	127	Comparison effect of early and delayed surgery treats neonatal necrotizing enterocolitis
		HE Chong-wei
		Objective To explore the effect of early and delayed surgery treats neonatal necrotizing enterocolitis(NEC).Methods A total of 102 children with NEC who were admitted to the Department of Pediatric Surgery,Maternal Maternal and Child Health Hospital from February 2015 to March 2020 were selected as the research subjects.They were divided into group A(51 cases)and group B(51 cases)according to different surgical method.The patients in group A were treated with early surgery,while those in group B were treated with delayed surgery.The short-term prognosis,total incidence of complications and follow-up after 6 months were compared between two groups.Results The cure rate of group A was higher than that of group B,and the proportion of disease deterioration to stageⅢand the total mortality after 6 months follow-up were lower than those of group B,the differences were statistically significant(P＜0.05).The total incidence of complications in group A was lower than that in group B,the difference was statistically significant(P＜0.05).The weight of group A was higher than that of group B 6 months after operation,and the total incidence of long-term complications was lower than that of group B,the differences were statistically significant(P＜0.05).Conclusion The treatment newborn necrotizing enterocolitis for prognosis by early surgery,cure rate is high,complications is little,prognosis is good,it is worth to be used.
		2021 Vol. 28 (14): 127-129 [Abstract] ( 45 ) HTML (30 KB) PDF (0 KB) ( 6 )

	130	Effect of biofeedback electrical stimulation+pelvic floor muscle exercise treats early postpartum stress urinary incontinence
		XIAO Li-li
		Objective To explore the effect of biofeedback electrical stimulation+pelvic floor muscle exercise treats early postpartum stress urinary incontinence.Methods A total of 78 patients with early postpartum stress urinary incontinence admitted to Shenyang Yongsen Hospital,Shengjing Hospital Affiliated to China Medical University were selected as the research objects.According to the random number table method,they were divided into control group and observation group,with 39 cases in each group.The control group only received pelvic floor muscle exercise,while the observation group received biofeedback electrical stimulation+pelvic floor muscle exercise.The urine leakage,improvement of pelvic floor muscle strength,short form of urinary incontinence questionnaire(ICIQ-SF)and female sexual function index(FSFI)scores were compared between the two groups.Results There was no significant difference in urine leakage between the two groups before treatment(P＞0.05).The amount of urine leakage in the observation group after treatment was less than that in the control group,and the difference was statistically significant(P＜0.05).After treatment,all indexes of pelvic floor muscle strength in observation group were higher than those in control group,and the difference was statistically significant(P＜0.05).There were no significant differences in ICIQ-SF and FSFI scores between the two groups before treatment(P＞0.05).After treatment,the ICIQ-SF score of the two groups was lower than that before treatment,and the FSFI score was higher than that before treatment,and the differences were statistically significant(P＜0.05).After treatment,the ICIQ-SF score of observation group was lower than that of control group,and the FSFI score was higher than that of control group,and the differences were statistically significant(P＜0.05).Conclusion The use of biofeedback electrical stimulation combined with pelvic floor muscle exercise in the treatment of early postpartum stress urinary incontinence can significantly improve the patient′s pelvic floor muscle function,reduce the symptoms of stress urinary incontinence,and promote the quality of sexual life of patients It has a good recovery effect and is worth recommending.
		2021 Vol. 28 (14): 130-133 [Abstract] ( 43 ) HTML (36 KB) PDF (0 KB) ( 5 )

	134	Epidemiological investigation of allergic rhinitis in children in Ganzhou area and clinical effect of Dermatophagoides Farinae Drops
		WANG Xin-tao； YANG Ming-fu ；GAO Shu-feng ；ZHANG Ke-hui ；HUANG Zhen-he ；CAI Yun-xiang； HUANG Yun
		Objective To investigate the epidemiology of allergic rhinitis in children in Ganzhou area,and to analyze the clinical efficacy of Dermatophagoides Farinae Drops.Methods A total of 160 children with allergic rhinitis were investigated in Ganzhou area from January 2018 to January 2020.The clinical symptoms and the standard allergen skin prick test(SPT)were recorded.The symptoms scores change and clinical sign score changes before and after treatment,curative effect and adverse reactions were observed.Results The mainly clinical symptoms of 160 children were sneezing and nasal congestion.Other nasal symptoms were nasal itching,runny nose and hyposmia.Among 160 children,there were 145 children with SPT positive,50 cases(34.48%)aged 5-7 years,63 cases(43.45%)aged 8-10 years,32 cases(22.07%)aged 11-14 years.Among them,the positive rate of dust mite sting was the highest,accounting for 78.62%,followed by corn pollen and willow pollen.After treatment,the scores of symptoms and clinical signs of sneezing,runny nose,nasal congestion,and nasal itching were lower than those before treatment(P＜0.05).Among the 160 children,102 cases were markedly effective(63.75%),54 cases were effective(33.75%),4 cases were ineffective(2.50%),and the total effective rate was 97.50%,the incidence of adverse reactions was 5.00%.Conclusion The mainly clinical symptoms of children with allergic rhinitis are sneezing,and most of the children′s skin prick tests are allergic to dermatophagoides farinae.The application of sublingual Dermatophagoides Farinae Drops can help improve the clinical symptoms and clinical signs,and the adverse reaction rarely occurr.
		2021 Vol. 28 (14): 134-137 [Abstract] ( 47 ) HTML (34 KB) PDF (0 KB) ( 8 )

	138	Effect of non-brackets invisible correction method in the treatment of malocclusion deformity patients
		NI Hui；WANG Hao；SHI Zhi-qiang
		Objective To explore the effect of non-brackets invisible correction method in the treatment of malocclusion deformity patients.Methods A total of 50 cases of malocclusion deformity treated in Shenzhen Hospital of the Chinese Academy of Sciences from October 2017 to October 2018 were selected as the research objects,and they were divided into the control group and the observation group by random number table method,with 25 cases in each group.The control group used fixed orthodontics method,and the observation group used non-brackets invisible correction method.The gingival index(GI),periodontal pocket probing depth(PD),sulcus bleeding index(SBI)and plaque index(PLI),the time required for tilted and turned teeth to be completely twisted and the clinical effect were compared between the two groups.Results The total effective rate of treatment in the observation group was 96.00%,which was higher than 72.00% in the control group(P＜0.05).There were no significant differences in GI,PD,SBI and PLI between the two groups before treatment(P＞0.05).The GI,PD,SBI,and PLI indicators of the study group after treatment were lower than those of the control group,and the differences were statistically significant(P＜0.05).The time required for tilted and turned teeth to be completely twisted in the observation group was shorter than that in the control group(P＜0.05).Conclusion Non-brackets invisible correction method in the treatment of malocclusion deformity can improve the patients′oral health during the treatment process,speed up the recovery of the tooth arrangement,and at the same time be more beautiful,comfortable and effective.
		2021 Vol. 28 (14): 138-140转161 [Abstract] ( 34 ) HTML (32 KB) PDF (0 KB) ( 10 )

	141	Influence of nasal endoscopic surgery combined with glucocorticoids on serum inflammatory factors and recurrence in patients with nasal polyps
		LIU Yun-xiang；HUANG Min；ZHANG Zhi-yuan
		Objective To investigate the clinical effect of nasal endoscopic surgery combined with glucocorticoids in the treatment of patients with nasal polyps.Methods A total of 82 patients with nasal polyps admitted to the Third Hospital of Nanchang City in Jiangxi Province and the First Affiliated Hospital of Nanchang University from January 2018 to August 2019 were selected as study subjects.According to the random number table method,they were divided into the combined group(41 cases)and the control group(41 cases).The control group was treated with nasal endoscopic surgery,and the combined group was treated with glucocorticoid on the basis of the control group.Perioperative indicators,clinical efficacy,inflammatory factors and recurrence were compared between the two groups.Results Intraoperative blood loss in the combined group was less than that in the control group,the length of hospital stay and operation time in the combined group were shorter than those in the control group,and the total effective rate of treatment in the combined group was higher than that in the control group,with statistically significant differences(P＜0.05).The levels of IL-17 and IL-5 in the combined group at 6 months after surgery were(2.65±1.05)g/L and(152.64±21.65)ng/L,which were lower than those in the control group([3.35±1.21]g/L and([182.21±25.21]ng/L),with statistically significant differences(P＜0.05).The recurrence rate of the combined group was 4.88%,which was lower than that of the control group(24.39%),and the difference was statistically significant(P＜0.05).Conclusion Nasal endoscopic surgery combined with glucocorticoid in the treatment of nasal polyps can improve the treatment effect,reduce blood loss,shorten the operation time and hospital stay,reduce the level of inflammatory factors and the recurrence rate.
		2021 Vol. 28 (14): 141-143 [Abstract] ( 49 ) HTML (31 KB) PDF (0 KB) ( 5 )

	144	Application effect of transvaginal color Doppler ultrasound combined with transabdominal color Doppler in diagnosis of acute abdomen in obstetrics and gynecology
		MAO Nan； LU Guan-nan
		Objective To study and analyze the application effect of transvaginal and transabdominal color Doppler abdomen in obstetrics and gynecology.Methods From September 2018 to September 2019,a total of 122 patients with acute abdomen from Liaoning Tieling Central Hospital were selected as subjects.They were divided into observation group and routine group by the random digital table method,61 cases in each group.Patients in the routine group were diagnosed by transabdominal color Doppler ultrasound,while the patients in the observation group were diagnosed by transvaginal color Doppler ultrasound combined with transabdominal color Doppler ultrasound.According to the diagnostic criteria of pathological examination,the diagnostic coincidence rate of the two groups was compared with pathological examination.Results The overall diagnostic coincidence rate of the patients in the observation group was 96.72%,it was higher than that in the routine group which was 78.69%,and the difference was statistically significant(P＜0.05).In the observation group,the diagnostic coincidence rates of the four types of obstetrics and gynecology acute abdomen,including ruptured corpus luteum,abruption of placenta,acute pelvic inflammatory disease,and torsion of ovarian tumor pedicle,were all higher than those in the routine group,and the differences were statistically significant(P＜0.05).Compared with the two groups in the diagnosis of ectopic pregnancy,there was no significant difference(P＞0.05).Conclusion Transabdominal color Doppler ultrasound combined with transvaginal color Doppler ultrasound for diagnosis of acute abdomen in obstetrics and gynecology can better identify the etiology,improve the diagnostic coincidence rate,has a better clinical application value.
		2021 Vol. 28 (14): 144-146 [Abstract] ( 39 ) HTML (29 KB) PDF (0 KB) ( 7 )

	147	Predictive value of renal artery resistance index on contrast-induced acute kidney injury in patients with type 2 diabetes mellitus after percutaneous coronary intervention
		LI Jiao； LUO Qin； YANG Zhao； YI Yong-zhong
		Objective To explore the predictive value of renal artery resistance index(RRI)on contrast-induced acute kidney injury(CI-AKI)in patients with type 2 diabetes mellitus(T2DM)after percutaneous coronary intervention(PCI).Methods A total of 100 cases of T2DM patients who underwent PCI treatment in Pingxiang People′s Hospital from January 2020 to September 2020 were selected as the research objects.According to CI-AKI diagnostic criteria,they were divided into a CI-AKI group(n=30)and a non-CI-AKI group(n=70).The baseline data,serum creatinine(Scr)levels and RRI between the two groups were compared,and the influencing factors of CI-AKI in patients with T2DM after PCI were analyzed,the receiver operating characteristic(ROC)curve was drawn to judge the value of contrast agent dose,peak systolic velocity(PSV)of renal artery,end diastolic velocity(EDV),Scr levels and RRI in the detection of CI-AKI.Results The results of univariate analysis showed that there were statistical significant differences in compared contrast dose,PSV and EDV between CI-AKI group and non CI-AKI group(P＜0.05);the levels of Scr at 24 h and 48 h after operation and RRI at 24 h after operation in CI-AKI group were higher than those in non CI-AKI group(P＜0.05);the results of Logistic multivariate analysis showed that the dose of contrast medium(β=0.048,OR=1.050,95%CI=1.031-1.069),PSV(β=-0.301,OR=0.832,95%CI=0.803-0.982),EDV(β=-0.356,OR=0.625,95%CI=0.531-0.878),Scr level(β=0.063,OR=1.065,95%CI=1.042-1.090),RRI(β=2.999,OR=20.063,95%CI=1.204-334.228)were the related influenccing factors of CI-AKI in T2DM patients after PCI(P＜0.05).ROC curve was drawn,and the results showed that contrast agent dose,PSV,EDV,Scr,RRI detected the area under the curve(AUC)of patients with T2DM after PCI were 0.880,0.928,0.971,0.878 and 0.925,respectively,the sensitivity of each index were 97.0%,97.1%,95.7%,98.6% and 97.2% respectively,all higher than 90.0%,but the specificity of RRI was the highest(96.7%),therefore,the predictive value of RRI in detection of CI-AKI was higher.Conclusion Higher dose of contrast agent,PSV,EDV,Scr level and RRI are the influencing factors for the occurrence of CI-AKI after PCI in T2DM patients,among them,RRI can better predict CI-AKI.Early detection of RRI has important value for the early diagnosis and clinical diagnosis and treatment of CI-AKI after PCI treatment for T2DM.
		2021 Vol. 28 (14): 147-150 [Abstract] ( 30 ) HTML (35 KB) PDF (0 KB) ( 7 )

	151	Application value of ultrasound differential diagnosis in patients with chronic granulomatous mastitis and breast cancer
		LI Na
		Objective To explore the application value of ultrasound differential diagnosis in patients with chronic granulomatous mastitis and breast cancer.Methods A total of 102 patients with chronic granulomatous mastitis admitted to Dalian Hospital of Traditional Chinese Medicine from October 2018 to May 2020 were selected as the inflammatory group,and another 102 patients with breast cancer admitted to Dalian Hospital of Traditional Chinese Medicine during the same period were selected as the cancer group,all of whom were female.All patients were diagnosed by ultrasound,and the ultrasound image characteristics and blood flow were compared between the two groups.Results The morphological irregularity rate,marginal burr rate,posterior echo attenuation rate and microcalcification rate in the cancer group were higher than those in the inflammatory group,with statistically significant differences(P＜0.05).In the cancer group,the proportions of blood stream classⅡ-Ⅲ,shunt blood flow resistance index(RI)≥0.7 and carotid artery peak systolic flow rate(PSV)≥30 cm/s in the cancer group were higher than those in the inflammatory group,with statistically significant differences(P＜0.05).Conclusion The difference between chronic granulomatous mastitis and breast cancer can be distinguished according to the image characteristics of ultrasound.The RI index,PVS value and other blood flow distribution at the lesions of the body can also be shown in the ultrasound images.Ultrasound provides valuable reference basis for clinical diagnosis and treatment,which is worthy of popularization and application.
		2021 Vol. 28 (14): 151-154 [Abstract] ( 41 ) HTML (34 KB) PDF (0 KB) ( 4 )

	155	Characteristics of pelvic floor ultrasound in women with pelvic floor dysfunction
		QI Liu-qing；ZOU Ye-ping； ZENG Chun-jie；MEI Su-zhen
		Objective To explore the characteristics of pelvic floor ultrasound in women with pelvic floor dysfunction.Methods A total of 968 female patients with pelvic floor dysfunction admitted to Sanming Second Hospital,Fujian Province from September 2018 to August 2020 were selected as the observation group.A total of 968 female patients with non-pelvic floor dysfunction admitted to Sanming Second Hospital,Fujian Province from September 2018 to August 2020 were selected as the reference group.Pelvic floor ultrasound was used to diagnose the disease in both groups clinically.The ultrasound results of constrictive anal state,the resting state,and Valsalva test state were compared.Results The anteroposterior diameter(M)of levator ani muscle hiatus by ultrasound at the constrictive anal state in the observation group was(7.11±1.39)cm,and the transverse diameter(N)of levator ani muscle hiatus by ultrasound at the constrictive anal state in the observation group was(6.79±1.29)cm,both of which were longer than(5.53±1.29)cm and(5.10±1.03)cm in the control group;the angle(γ)between the left and right branches of levator ani muscle by ultrasound at the constrictive anal state in the observation group was(87.92±11.13)°,and the hiatus area(A)of levator ani muscle by ultrasound at the constrictive anal state in the observation group was(19.95±3.39)cm2,both of which were higher than those of the control group of(74.65±9.45)° and(12.55±2.52)cm2;the pectineal visceral muscle thickness(C)by ultrasound at the constrictive anal state of the observation group was(0.99±0.37)cm,which was thicker than that of the control group of(0.81±0.29)cm,the differences were statistically significant(P＜0.05).The ultrasound M and N of the observation group in the resting state were(6.69±1.27)cm and(6.53±1.25)cm,both longer than those of the control group of(5.65±1.05)cm and(5.12±1.06)cm;the γ of the observation group in the resting state was(85.65±10.03)°,A of the observation group in the resting state was(18.55±3.23)cm2,higher than(73.27±8.67)° and(13.12±2.19)cm2 in the control group;the C of the observation group in the resting state was(0.96±0.32)cm,thicker than(0.82±0.23)cm in the control group,and the differences were statistically significant(P＜0.05).Ultrasound M and N of Valsalva status in the observation group were(7.12±1.39)cm and(6.83±1.41)cm,both longer than those in the control group of(5.69±1.30)cm and(5.44±1.37)cm;the γ of Valsalva status in the observation group was(88.25±11.43)°,A of Valsalva status in the observation group was(19.95±3.53)cm2,both higher than(72.43±8.95)° and A(15.69±3.03)cm2 in the control group;the C of Valsalva status in the observation group was(0.99±0.36)cm,thicker than(0.77±0.30)cm in the control group,the differences were statistically significant(P＜0.05).Conclusion The use of pelvic floor ultrasound can provide information for the effective diagnosis of female pelvic floor dysfunction
		2021 Vol. 28 (14): 155-157 [Abstract] ( 36 ) HTML (31 KB) PDF (0 KB) ( 6 )

	158	Clinical experience of professor Li Changsheng in treatment of ischemic stroke in convalescent period
		ZANG Cui-cui
		With the continuous improvement of our people′s living standard,the incidence of ischemic stroke is increasing year by year,especially the incidence of sequelae and the incidence of recurrence after recovery have increased significantly,and there is a younger trend,which seriously affects people′s quality of life and physical and mental health.On the basis of traditional Chinese medicine diagnosis and treatment of stroke,especially on the recovery of the treatment effect is obvious.Professor Li Changsheng believes that qi deficiency and blood stasis are the main pathogenesis of ischemic stroke in the recovery period,over time,it will resolve phlegm and cause poison,and damage the spleen and kidney.According to the pathogenesis characteristics of ischemic stroke recovery period,he pays attention to promoting blood circulation and removing blood stasis during treatment,at the same time,replenishing qi and blood,regulate stomach and kidney,developed a series of empirical prescriptions with remarkable curative effect.
		2021 Vol. 28 (14): 158-161 [Abstract] ( 46 ) HTML (32 KB) PDF (0 KB) ( 6 )

	162	Clinical observation of scraping combined with thermal moxibustion in the treatment of chronic cough with wind-cold attack on the lungs
		CHEN Ting-ting； LU Sheng-zhen
		Objective To explore the clinical effect of scraping combined with thermal moxibustion in the treatment of chronic cough with wind-cold attack on the lungs.Methods A total of 100 patients with chronic cough of wind-chill type who were admitted to Jiangxi Hospital of Integrated Traditional Chinese and Western Medicine from September 2019 to July 2020 were selected as the research objects.According to the random number table method,they were divided into the observation group and the control group,50 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with scraping combined with thermal moxibustion on the basis of the control group.The cough symptom scores,traditional Chinese medicine(TCM)symptom scores,satisfaction and the incidence of adverse reactions were compared between the two groups.Results After treatment,cough symptom scores and TCM symptom scores of the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,the scores of cough symptoms and TCM symptoms in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).The satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Scraping combined with thermal moxibustion for patients with chronic cough of wind-cold lung type has a significant effect on improving clinical symptoms,improving patient satisfaction and reducing the incidence of adverse reactions,and it is worthy of clinical promotion.
		2021 Vol. 28 (14): 162-165 [Abstract] ( 45 ) HTML (33 KB) PDF (0 KB) ( 8 )

	166	Study on decocting technology of Hugan Lishi Ointment
		WU Sheng-zhen； WU Su-zhen； WU Xiang-wei； Deng Li-chang
		Objective To optimize the decocting technology of Hugan Lishi Ointment.Methods L9(34)orthogonal test method was used with soaking time,water volume,decoction duration and number of times of decoction as the influencing factors.The content of peoniflorin and berberine hydrochloride were taken as the evaluation indices to optimize the decoction process of Hugan Lishi Ointment.Results The optimal extraction conditions were as follows,medicinal materials were soaked for 4 hours before extraction,and extracted with water volume of 8 times of the medicinal materials for two times,40 min each time.Conclusion The optimized decoction technology can provide reference for the production of Hugan Lishi Ointment.
		2021 Vol. 28 (14): 166-169 [Abstract] ( 41 ) HTML (34 KB) PDF (0 KB) ( 5 )

	170	Effect of Xiezhuo Chubi Decoction and external application of Xiaoyu Jiegu Powder on knee osteoarthritis
		YANG Yang
		Objective To explore effect of Xiezhuo Chubi Decoction and external application of Xiaoyu Jiegu Powder on knee osteoarthritis(KOA).Methods A total of 96 patients with KOA admitted to Dandong People′s Hospital from January 2019 to May 2020 were selected as the research subjects.According to random number table method,they were divided into the control group and the observation group,with 48 cases in each group.The control group was treated with Celexoxib Capsule,and the observation group was additionally treated with Xiezhuo Chubi Decoction and external application of Xiaoyu Jiegu Powder.Visual analogue scale(VAS)score,osteoarthritis index(WOMAC)score,articular fluid tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),matrix metalloproteinase-L(MMP-1),MMP-3 levels before and after treatment were compared between two groups.Results The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,VAS score and WOMAC score of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05).After treatment,the levels of TNF-α,IL-6,MMP-L and MMP-3 in the articular fluid in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Xiezhuo Chubi Decoction combined with external application of Xiaoyu Jiegu Powder for the treatment of KOA patients can reduce the expression of MMP-1 and MMP-3 in synovial fluid,reduce inflammation,relieve pain,and improve knee joint function.The effect is significant.
		2021 Vol. 28 (14): 170-172转176 [Abstract] ( 47 ) HTML (33 KB) PDF (0 KB) ( 8 )

	173	Clinical effect of traditional Chinese medicine soaking therapy combined with infrared radiation treating chronic cholecystitis
		ZHANG Ya-qing
		Objective To observe the clinical effect of traditional Chinese medicine soaking therapy combined with infrared radiation treating chronic cholecystitis.Methods A total of 104 patients with chronic cholecystitis admitted to Huludao Central Hospital from January 2019 to January 2020 were selected and divided into the experimental group and the control group by random number table method,with 52 cases in each group.The patients in the control group were given conventional treatment,and the experimental group was treated with infrared radiation therapy combined with traditional Chinese medicine soaking therapy on the basis of the control group.The visual analogue scale(VAS)score,pain disappearance time,World Health Organization summary table of quality of life measurement(WHOQOL-100)score before and after treatment,clinical treatment effect and recurrence rate after 10 months follow-up were compared between the two groups.Results At 1 day after treatment,there was no statistically significant difference in VAS score between the two groups(P＞0.05).At 1,2 and 4 weeks after treatment,the VAS scores of experimental group were lower than those of the control group,and the differences were statistically significant(P＜0.05).The pain disappearance time in experimental group was shorter than that in control group,and the difference was statistically significant(P＜0.05).Before treatment,there was no statistically significant difference in WHOQOL-100 score between the two groups(P＞0.05).After treatment,the WHOQOL-100 scores in the two groups were higher than those before treatment,and the WHOQOL-100 score in the experimental group was higher than that in the control group,and the differences were statistically significant(P＜0.05).The total effective rate of the experimental group was 98.08%,which was higher than that of the control group(86.54%),and the difference was statistically significant(P＜0.05).The recurrence rate in experimental group was lower than that in control group,and the difference was statistically significant(P＜0.05).Conclusion In the treatment of patients with chronic cholecystitis,the use of traditional Chinese medicine soaking therapy combined with infrared radiation and conventional treatment can significantly reduce the pain of patients after treatment,shorten the pain time,improve the total effective rate of clinical treatment,improve the quality of life of patients,and reduce the recurrence rate after treatment.It is worthy of clinical promotion and application.
		2021 Vol. 28 (14): 173-176 [Abstract] ( 51 ) HTML (32 KB) PDF (0 KB) ( 5 )

	177	Application effect of Liqi Huoxue Decoction combined with Gestrienone in the treatment of ovarian endometriosis after laparoscopic conservative surgery
		ZHENG Ying-hui； CHEN Xuan-qiong
		Objective To observe the clinical effect of Liqi Huoxue Decoction combined with Gestrinone on the treatment of ovarian endometriosis(OEMs)after laparoscopic conservative surgery.Methods A total of 68 patients with OEMs undergoing laparoscopic conservative surgery who treated in Guangzhou Hospital of Integrated Traditional and Western Medicine from June 2017 to June 2019 were selected as the research objects.According to random number table method,they were divided into control group and observation group,34 cases in each group.The control group was orally taken Gestrinone Capsule after surgery,and the observation group was additively taken Liqi Huoxue Decoction on the basis of the control group.The two groups were treated for 3 months.The duration of dysmenorrhea,visual analog scale(VAS)score,serum estradiol(E2),follicle stimulating hormone(FSH),cancer antigen 125(CA125)and positive rate of anti-endometrial antibody(EMAb)were compared between two groups before and after treatment.Results After treatment,the duration of dysmenorrhea in both groups was shorter than before treatment,VAS score,levels of E2,FSH,CA125 and positive rate of EMAb were lower than before treatment,the differences were statistically significant(P＜0.05).The duration of dysmenorrhea after treatment in the observation group was shorter than that in the control group,the VAS score,E2,FSH,CA125 levels and the positive rate of EMAb were all lower in the observation group than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Liqi Huoxue Decoction combined with Gestrinone in the treatment of patients with OEMs after laparoscopic conservative surgery can significantly shorten the dysmenorrhea time,reduce the VAS score,reduce the serum E2,FSH,CA125 levels and EMAb positive rate,and has a good curative effect.
		2021 Vol. 28 (14): 177-180 [Abstract] ( 38 ) HTML (37 KB) PDF (0 KB) ( 5 )

	181	Analysis of the relationship between human papillomavirus genotyping in female genital tract and cervical lesions
		CHEN Xin-Yao； ZHANG Jian； DING Yan-jia； MO Huan-tong
		Objective To study the correlation between Human papillomavirus(HPV)genotyping in female genital tract and cervical lesions.Methods From February 2015 to February 2020,a total of 648 patients with cervical biopsy in Chaozhou People′s Hospital Affiliated to Shantou University Medical College were selected and divided into group A(124 patients with high-grade squamous intraepithelial lesions),group B(308 patients with low-grade squamous intraepithelial lesions)and group C(216 patients with cervicitis)according to the degree of cervical lesions.HPV genotyping was performed in all patients to analyze the correlation between HPV genotypes and cervical lesions.Results The results of HPV genotyping showed that 105 patients were HPV positive among 648 patients,and the HPV positive rate was 16.20%.Among them,41 cases were HPV positive in group A,53 cases were HPV positive in group B,11 cases were HPV positive in group C.The HPV subtypes with the highest infection rate were HPV 52,16,81,58,68,53,33,18 and 39.The number of HPV positive,high-risk HPV(HR-HPV)and multi subtype infection in group A was higher than that in group B and group C,and the number of HPV positive,HR-HPV and multi subtype infection in group B was higher than that in group C(P＜0.05).The results of multivariate analysis showed that HPV infection(β=0.053,OR=1.763,95%CI=1.332-2.245)and HR-HPV infection(β=0.078,OR=2.452,95%CI=1.502-3.547)were risk factors for cervical cancer(P＜0.05).Conclusion HPV infection can increase the risk of cervical lesions in women,and HRHPV infection is an independent risk factor for cervical cancer.
		2021 Vol. 28 (14): 181-183转187 [Abstract] ( 43 ) HTML (30 KB) PDF (0 KB) ( 6 )

	184	Comparison of screening of Group B streptococcus by different detection methods in late pregnancy
		FAN Chun-hui； JIN Xian； ZHU Ping-an；TAN Ping；ZHANG Gen-fang； HUANG Xiao-tong； CHEN Fang
		Objective To explore the diagnostic value of bacterial cultivation,immunochromatography and real-time fluorescence quantitative PCR on Group B streptococcus in pregnant women of late pregnancy.Methods A total of 702 pregnant women in late pregnancy who underwent the obstetric examination in Yantian People′s Hospital of Shenzhen City from April 2018 to July 2019 were selected as the research objects.The vaginal-rectal secretions were collected as samples and detected by direct inoculation bacterial cultivation,immunochromatography and PCR.The samples were cultured in selective broth medium and then tested by the above three methods.The results of bacterial cultivation,immunochromatography and PCR before enrichment cultivation and the above three methods and after enrichment cultivation were collected.The sensitivity,specificity,accuracy and consistency of each test method were compared with gold standard of bacterial enrichment cultivation.Results The positive rate of bacterial cultivation before enrichment cultivation was 2.8%(20/702),and that after enrichment cultivation was 9.4%(66/702).The positive rate of immunochromatography and PCR before enrichment cultivation was 4.6%(32/702)and 8.5%(60/702).The positive rate of immunochromatography and PCR after enrichment cultivation was 13.8%(97/702)and 12.5%(88/702).The sensitivity,specificity,accuracy and consistency(Kappa)were 36.4%,98.7%,92.9% and 0.456 with immunochromatography before enrichment cultivation.The sensitivity,specificity,accuracy and consistency(Kappa)were 80.3%,93.1%,91.9% and 0.606 with immunochromatography after enrichment cultivation.The sensitivity,specificity,accuracy and consistency(Kappa)were 65.2%,97.3%,94.3% and 0.651 with PCR before enrichment cultivation.The sensitivity,specificity,accuracy and consistency(Kappa)were 87.9%,95.3%,94.6% and 0.724 with PCR after enrichment cultivation.Conclusion The positive rate of Group B streptococcus is higher in enrichment of bacteria in selective broth medium.The positive detection rate of immunochromatography and PCR is higher than that of bacterial cultivation.PCR has the advantages of high sensitivity,good consistency,short time-consuming and batch operation.
		2021 Vol. 28 (14): 184-187 [Abstract] ( 52 ) HTML (34 KB) PDF (0 KB) ( 6 )

	188	Study of high-risk human papillomavirus infection and its relationship with cervical lesions in opportunistic screening population of Yu′an District in Lu′an City
		JIN Guang-yu
		Objective To study the infection characteristics of high-risk human papillomavirus(HR-HPV)in the opportunistic screening population of Yu′an District in Lu′an City,to understand the HR-HPV in cervical lesions,and to explore the infection characteristics of HR-HPV in different cervical lesions.Methods From November 2018 to November 2019,1839 cases who received opportunistic screening for cervical cancer in the Gynecological Outpatient and Physical Examination Center of Lu′an Shili Hospital were selected as the research subjects.The polymerase chain reaction(PCR)fluorescence quantitative was used to detect 13 kinds of HR-HPV,and the results of HR-HPV detection and cervical liquid-based thin layer cytology(TCT)were further compared and analyzed.The distribution of HRHPV infection subtypes and its relationship with cervical lesions were also analyzed.Results Among the 1839 patients,407 cases of HR-HPV were positive.The overall HR-HPV infection rate was 22.13%.Among them,type 52 HR-HPV was the most infected,followed by type 16 and type 58.The infection rate of HR-HPV gradually increased with the increase of age,and the infection rate in the group aged over 60 years was as high as 36.92%.In the TCT examination,the HR-HPV infection rate reached 100.00% in the cases diagnosed as glandular epithelial lesions tending to adenocarcinoma.The most infected HR-HPV type in the cases diagnosed as low-grade disease was type 52,while the most infected HR-HPV type in the cases of high-grade disease and squamous cell carcinoma was type 16.Conclusion In the population of opportunistic screening of Yu′an District in Lu′an City,type 52 HR-HPV is the most infected,followed by type 16,but cervical disease is more severe among patients infected with type 16 HPV.When the corresponding HR-HPV infection type is detected,clinical intervention and treatment should be timely to prevent the occurrence of cervical cancer.
		2021 Vol. 28 (14): 188-192 [Abstract] ( 43 ) HTML (36 KB) PDF (0 KB) ( 5 )

	193	Analysis on the clinical standard use and risk control of proton pump inhibitor drugs for injection
		LIU Qing-qing；YANG Jing-ran；ZHANG Hui-feng； LIU Yu； HOU Jian-li； TANG Chun-yan； GUO Lu-ping；HU Dong-xiong
		Objective To explore the standardization and rationality of the clinical use of proton-pump inhibitors(PPIs)for injection in a top three hospital in Yunnan Province.Methods A total of 324 clinical medical records of PPIs for injection were retrospectively analyzed in a top three hospital in Yunnan Province from January 2018 to December 2019,as well as its use population,preventive and therapeutic use of PPIs related stressors and high-risk factors.Results In all of 324 medical records using PPIs,there were more men than women,45.37% of whom were 65 years old or older.A total of 193 cases of preventive medication(59.57%),among which stress ulcer was the most common(105 cases,32.41%),followed by non-steroidal anti-inflammatory drugs-related ulcers(36 cases,11.11%).A total of 131 cases of therapeutic drugs(40.43%),abdominal pain was more common(57 cases,17.59%).Conclusion Preventive use of PPIs can effectively reduce stress ulcer,drug-related ulcer and risk of gastrointestinal mucosal damage,but not an absolute indication of the use of PPIs.PPIs can be used preventively for patients related stressors and high-risk factors.
		2021 Vol. 28 (14): 193-195转204 [Abstract] ( 50 ) HTML (30 KB) PDF (0 KB) ( 8 )

	196	Investigation on the present situation of midwifery and the application of appropriate midwifery techniques in basic hospitals of Foshan City
		CAI Feng-tian； ZHUANG Xiao-hua； LIN Cai-hong
		Objective To investigate the status of midwifery work in primary hospitals in Foshan City and the application of appropriate technology for midwifery.Methods From January to December 2019,a questionnaire survey was made on the status of midwifery work and the application of appropriate technique for midwifery from 43 class-B and below primary hospitals in Foshan City.The Wenjuanxing questionnaire survey was used and sent to the head nurses of obstetric departments and senior responsible nurses designated by the head nurse in each primary hospital through WeChat to fill it out.Results Among the 43 primary hospitals,35(81.4%)hospitals needed to increase midwives.The rate of midwives receiving standardized training was 16.15%.There were 31(72.1%)carrying out free-position delivery,Lamaze breathing pain reduction 27(62.8%),SPA analgesia 20(46.5%),Doula accompany delivery 24(55.8%),free position delivery 23(53.5%),and water delivery 1(2.3%).The main reasons for not carrying out free postnatal preparation in 12 hospitals were lack of midwives,lack of training and lack of support from doctors.16 hospitals did not carry out Lamaze breathing pain relief mainly because of lack of midwives and lack of training.The main reasons for not carrying out hydrotherapy analgesia in 23 hospitals were lack of training and lack of support from doctors.29 did not carry out Doula accompanied delivery mainly because of the lack of midwives.The main reasons for not carrying out free position delivery in 20 hospitals were safety risks,lack of midwives,lack of training and lack of support from doctors.Safety concerns,lack of support from doctors and lack of training were cited as the main reasons for the failure of 42 water births.Conclusion A shortage of midwifery human resources in most of the primary hospitals in Foshan City is existed,which will increase the demand for midwives.The probability of midwives receiving standardized training is low,and the application rate of appropriate technique for midwifery is poor.It is necessary to update the concepts of managers and midwives,strengthen the standardized training for midwives,improve the service ability and competence of midwives,and promote the application of appropriate techniques for midwifery and natural delivery to ensure the safety of mothers and babies.
		2021 Vol. 28 (14): 196-199转212 [Abstract] ( 47 ) HTML (38 KB) PDF (0 KB) ( 6 )

	200	Foot self-management behavior and its influencing factors of diabetic high-risk foot patients in peritoneal dialysis centers
		WU Qian； LIU Ze-ping；GUO De-jiu； XU Ni
		Objective To observe the condition of self-management behavior in diabetic high-risk foot patients and explore its influencing factors in peritoneal dialysis centers.Methods A total of 284 patients with diabetic high-risk foot who were treated and followed up in peritoneal dialysis centers of three tertiary A hospitals in Guangzhou from November 2018 to November 2019 were selected as the research objects,and the diabetic foot self-management behavior scale,chronic disease self-efficacy scale and social support rating scale were used for evaluation.Results The total score of foot self-management behavior of high-risk diabetic foot patients in the peritoneal dialysis center was(19.14±7.64)points.Self-efficacy,diabetes health education,diabetic foot health education,the proportion of medical expenses,and the age of dialysis affected foot self-management level of the patients(P＜0.05).Conclusion The low level of foot self-management behavior in patients at high risk of diabetic foot in peritoneal dialysis centers should be taken seriously by medical personnel.
		2021 Vol. 28 (14): 200-204 [Abstract] ( 43 ) HTML (39 KB) PDF (0 KB) ( 5 )

	205	Study of peer education on psychological intervention of family members of children with supracondylar fracture of humerus
		LI Xia-yan； WU Yan； LEI Jia-fang
		Objective To study the influence of peer education on psychological intervention of family members of children with humeral supracondylar fracture.Methods A total of 60 families of children with supracondylar fracture of humerus treated in Jiangxi Children′s Hospital from October 2019 to August 2020 were selected as the research subjects.According to the order of hospitalization of the children,they were divided into the observation group and the control group,with 30 family members in each group.The observation group was given peer education psychological intervention,while the control group was given conventional psychological nursing intervention.Mental health score,quality of life score,nursing compliance rate and nursing satisfaction were compared between the two groups.Results The psychological scores of somatization,interpersonal sensitivity,depression,anxiety,terror and other psychological scores in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).The quality of life scores of the families in the observation group were higher than those in the control group in physiological field,psychological field,social relationship field,environment field,and other fields,and the differences were statistically significant(P＜0.05).The total nursing compliance rate and total nursing satisfaction of the children′s families in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Peer education psychological intervention for the families of children with supracondylar fractures of the humerus can significantly improve their mental health and quality of life.At the same time,it can also greatly improve the nursing compliance rate and nursing satisfaction of the families of the children to a certain extent.
		2021 Vol. 28 (14): 205-208 [Abstract] ( 38 ) HTML (34 KB) PDF (0 KB) ( 6 )

	209	Application of image and text teaching combined with feedback teaching method in health education of patients after percutaneous coronary intervention
		FANG Yan-na； FU Dan-xian
		Objective To explore the application effect of image and text teaching combined with feedback teaching method in health education of patients after percutaneous coronary intervention(PCI).Methods From January to June 2020,108 patients with acute myocardial infarction who were hospitalized in Puning Overseas Chinese Hospital and underwent PCI were selected as the research objects,and they were divided into the control group and the observation group by random number table method,with 54 cases in each group.The control group received regular health education,and the observation group received health education with image and text teaching combined with feedback teaching method.The medication compliance,related knowledge scores after PCI,the incidence of angina and the rate of rehospitalization were compared between the two groups.Results Three months after discharge,the medication compliance rate and related knowledge scores after PCI of the observation group were higher than those of the control group,the incidence of angina and rehospitalization rate were lower than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion Image and text teaching combined with feedback teaching method can improve the medication compliance of patients after PCI and the mastery of related knowledge after PCI,and reduce the incidence of angina and rehospitalization.
		2021 Vol. 28 (14): 209-212 [Abstract] ( 45 ) HTML (34 KB) PDF (0 KB) ( 6 )

	213	Effects of WeChat platform distance education on blood glucose selfmanagement ability and delivery mode of gestational diabetes patients
		KE Ying； XIAO Lang-hua
		Objective To explore the effects of WeChat platform distance education on blood glucose self-management ability and delivery mode in patients with gestational diabetes mellitus.Methods A total of 100 patients with gestational diabetes diagnosed and treated in Ganzhou Maternal and Child Health Care Hospital from January to October 2019 were selected as the research subjects.According to random number table method,they were divided into control group(50 cases)and observation group(50 cases).The control group was given routine health education,and the observation group was given WeChat platform remote dynamic continuing education.The levels of 2 h postprandial blood glucose(2 h PG),fasting blood glucose(FBG),glycosylated hemoglobin(HbA1c),compliance and delivery mode in two groups were compared.Results Before intervention,there was no statistical significance in the levels of 2 h PG,FBG and HbA1c between the two groups at 2 h(P＞0.05).After intervention,2 h PG level in the observation group was(6.52±1.35)mmol/L,FBG was(5.10±1.20)mmol/L,lower than those in the control group(7.81±1.30)mmol/L,(6.05±1.25)mmol/L,and the differences were statistically significant(P＜0.05).The HbA1c level in the observation group was(6.04±0.25)%,lower than that in the control group(6.67±0.65)%,and the difference was statistically significant(P＜0.05).The total compliance of the observation group was 98.00%,higher than that of the control group(84.00%),and the difference was statistically significant(P＜0.05).The vaginal delivery rate of the observation group was 90.00%(45/50)and the cesarean section rate was 10.00%(5/50),while the vaginal delivery rate of the control group was 72.00%(36/50)and the cesarean section rate was 28.00%(14/50),the rate of vaginal delivery was higher in the observation group than in the control group,and the difference was statistically significant(P＜0.05).Conclusion The use of WeChat platform distance education for patients with gestational diabetes can play the role of dynamic continuation education,improve the attention of patients to the condition,strengthen the ability of self-management and compliance of patients with blood glucose,reasonable control of blood glucose level,reduce the rate of cesarean section,and improve the pregnancy outcome of patients.
		2021 Vol. 28 (14): 213-215转219 [Abstract] ( 38 ) HTML (31 KB) PDF (0 KB) ( 6 )

	216	Effect of mind map health education on disease knowledge cognition and rehabilitation effect of family members of children with pneumonia
		LI Xiao-ping； LIU Ji； XIA Yu
		Objective To explore the effect of mind map health education on disease knowledge cognition and rehabilitation effect of family members of children with pneumonia.Methods From April 2018 to April 2020,94 children with pneumonia and 94 family members were selected and divided into the control group and the observation group according to random number table method,with 47 cases in each group.The control group was given routine health education,while the observation group was given mind mapping health education.The cognition level of disease knowledge,satisfaction,recovery and medication compliance of the families of the two groups were compared.Results Before the intervention,there was no significant difference in the cognition level of disease knowledge between the two groups(P＞0.05).After intervention,the scores of disease knowledge cognition level of family members in the two groups were higher than those before intervention,the differences were statistically significant(P＜0.05).After intervention,the disease knowledge cognition level of the families in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The total satisfaction of the families of children in the observation group was 97.87%,which was higher than that in the control group(80.85%),and the difference was statistically significant(P＜0.05).The time of cough disappearance([6.26±1.25]d),body temperature recovery time([4.03±1.17]d),lung rales disappearance time([5.48±1.39]d)and hospital stay([6.42±1.23]d)in the observation group were all shorter than those in the control group([7.83±1.64],[5.14±1.28],[6.54±1.75],[7.67±1.84]d),the differences were statistically significant(P＜0.05).The medication compliance of the observation group was better than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Mind map health education can significantly improve the knowledge level and satisfaction of the family members of children with pneumonia,and accelerate the rehabilitation process of children.
		2021 Vol. 28 (14): 216-219 [Abstract] ( 54 ) HTML (34 KB) PDF (0 KB) ( 6 )

	220	Training effect of pre-service training course for prospective nurses on comprehensive quality of ICU nurses and its influence on the reserve of talents
		MEI Jing
		Objective To explore training effect of pre-service training course for prospective nurses on comprehensive quality of intensive care unit(ICU)nurses and its influence on the reserve of talents.Methods A total of 46 ICU rotating trainees enrolled in the pre-service training course for prospective nurses of Jiujiang First People′s Hospital from 2017 to 2019 were selected as the observation group.A total of 46 recruited nurses who rotated in ICU from 2017 to 2019 were selected as the control group,and did not participate in the pre-service training course for prospective nurses.The results of the emergency response ability assessment,the qualified rate of the theoretical examination and the operational examination,the core competence of nurses and the satisfaction of the teaching teachers were compared between the two groups.Results The scores of nurse condition observation,emergency cooperation and rescue procedure evaluation in the observation group were all higher than those in the control group,the differences were statistically significant(P＜0.05).The qualified rate of theory examination and operation examination of nurses in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).The scores of core competence of nurses in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).The teacher satisfaction in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The pre-service training course for prospective nurses can improve the emergency response ability of nurses,improve the passing rate of theoretical operation examination and increase the satisfaction of teaching teachers,which has a positive effect on the cultivation of nurses′core competence and is conducive to the reasonable talent reserve of hospitals.
		2021 Vol. 28 (14): 220-223 [Abstract] ( 47 ) HTML (37 KB) PDF (0 KB) ( 6 )

	224	Application effect of CBL method combined with WeChat platform in the teaching of respiratory and critical care medicine
		SHI Hong-yang； ZHANG Yong-hong； WANG Yu； SHI Jie； LI Wei ；MING Zong-juan
		Objective To explore the application effect of case-based learning(CBL)combined with WeChat platform in probation teaching of respiratory and critical medicine.Methods A total of 100 undergraduate clinical students who were on internship in the Second Affiliated Hospital of Xi′an Jiaotong University Respiratory and Critical Care Medicine Department from October to December 2018 were selected as the research objects.According to the random number table method,they were divided into a joint teaching group and a traditional teaching(LBL)group,with 50 students in each group.CBL combined WeChat platform was used in the joint teaching group,while traditional teaching method was used in the LBL group.The results of entrance examination and teaching satisfaction(included stimulated learning interest,improved self-learning ability,improved comprehensive analysis ability,improved information acquisition ability,strengthen clinical practice ability,and deepen classroom understanding)of the two groups of medical students were compared.Results The total score of assessment in the combined teaching group was higher than that in the LBL group,the difference was statistically significant(P＜0.05).The satisfaction in five aspects of stimulating learning interest,improving self-learning ability,improving information acquisition ability,strengthening clinical practice ability and deepening classroom understanding and total satisfaction of the joint teaching group were higher than those of the LBL group,the differences were statistically significant(P＜0.05).However,there was no significant difference between the two groups in the satisfaction of improving the comprehensive analysis ability(P＞0.05).Conclusion The joint teaching group can significantly improve the quality of probation teaching in respiratory and critical care medicine,and increase the satisfaction of students in the aspects of learning interest,autonomous learning ability,clinical thinking ability,team cooperation ability and doctor-patient communication skills.
		2021 Vol. 28 (14): 224-227 [Abstract] ( 48 ) HTML (37 KB) PDF (0 KB) ( 7 )

	228	Application of PBL teaching based on evidence-based medicine theory in clinical teaching of cardiology department
		SU Qiang； DAI Ri-xin ；YANG Xi-heng ；LYU Xiang-wei； LI Jin-yi
		Objective To explore the application effect of problem-based teaching method(PBL)based on evidencebased medicine(EBM)theory in clinical teaching of cardiovascular medicine.Methods A total of 62 clinical interns who rotated in the Affiliated Hospital of Guilin Medical College Vasculocardiology Department from June 2018 to October 2019 were selected as the research objects.According to random number table method,they were divided into the control group and the research group,with 31 clinical interns in each group.The traditional teaching method was used in the control group,while the PBL teaching method based on EBM theory was used in the research group.At the end of the internship,the basic theoretical knowledge and the total scores of comprehensive case analysis of the two groups and the satisfaction of the two groups of interns on the teaching methods were compared.Results After internship,the basic theoretical knowledge and comprehensive case analysis scores in the research group were higher than those in the control group,the differences were statistically significant(P＜0.05).The teaching satisfaction of the research group was higher than that of the control group in four aspects,included teaching content and methods,improving the ability of literature review,strengthening the initiative of learning and training the clinical work ability,the differences were statistically significant(P＜0.05).Conclusion EBM-based PBL model is applicable to improve the teaching effects and the student′s learning satisfaction in clinical cardiology.
		2021 Vol. 28 (14): 228-230转234 [Abstract] ( 38 ) HTML (31 KB) PDF (0 KB) ( 6 )

	231	Application of nurse led lung rehabilitation training in nursing of patients with lung cancer undergoing radiotherapy
		LIAO Guang-jing；ZOU Yu-fen； HUA Mei
		Objective To explore the application value of nurse led lung rehabilitation training in nursing of patients with lung cancer undergoing radiotherapy.Methods A total of 58 patients with lung cancer treated in the First Affiliated Hospital of Gannan Medical University from January 2017 to December 2019 were selected and divided into the observation group(n=29)and the control group(n=29)according to randomnumber table method.The control group was given routine nursing,and the observation group was given lung rehabilitation training on the basis of the control group,forced vital capacity(FVC),forced expiratory volume in one second(FEV1),FEV1/FVC，and quality of life were compared between two groups.Results After nursing,FVC,FEV1,FEV1/FVC in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).After nursing,the scores of common symptoms and complications,social function,psychological function,physical function and total score of the observation group were higher than those of the control group,the differences were statistically significant(P＜0.05).Conclusion The application of nurse led lung rehabilitation training in patients with lung cancer radiotherapy can enhance the lung function of patients,improve the quality of life,and can be widely used.
		2021 Vol. 28 (14): 231-234 [Abstract] ( 33 ) HTML (33 KB) PDF (0 KB) ( 7 )

	235	Application of comprehensive nursing in children with pertussis DNA positive complicated with other respiratory pathogen infections
		XIAO Chun-hong； LIU Jian-ping； LI Hui
		Objective To explore the application value of comprehensive nursing in children with pertussis DNA-positive and other respiratory pathogen infections.Methods From July 2018 to July 2020,100 children patients with pertussis DNA-positive complicated with other respiratory pathogen infections treated in Ganzhou Maternal and Child Health Hospital were selected.All the participants were divided into the reference group and the experimental group according to the order of the odd and even numbers,50 cases in each group.The reference group used routine nursing and the experimental group used comprehensive nursing.The effects of different nursing modes on the time to improvement of clinical symptoms,white blood cell count and C-reactive protein,and nursing satisfaction scores were compared.Results In the experimental group,the disappearing time of cough,throat pain and high fever were shorter than those of the reference group,with statistical differences(P＜0.05).The white blood cell count and C-reactive protein of the experimental group were lower than those of the reference group,and the differences were statistically significant(P＜0.05).The evaluations on service skills,nursing skills,communication skills and nursing comfort in the experimental group were higher than those in the reference group,with statistical differences(P＜0.05).Conclusion Comprehensive nursing for children with DNA-positive pertussis complicated with other respiratory pathogen infections can quickly stabilize the disease conditions and improve the physical discomfort of the children.It can achieve the purpose of adjuvant therapy and is worthy of promotion.
		2021 Vol. 28 (14): 235-238 [Abstract] ( 33 ) HTML (32 KB) PDF (0 KB) ( 8 )

	239	Application of remote continuing nursing in recurrent respiratory infection in children
		TANG Wei； GUO Jie； ZHANG Min； DENG Sha； HE Zhao ；MI Shu-ping
		Objective To investigate the application effect of remote continuing nursing in recurrent respiratory infection(RRTI)in children to provide reference for reducing the recurrence rate of RRTI in children.Methods A total of 60 children with RRTI who were discharged from Pingxiang People′s Hospital in Jiangxi Province from August 2018 to August 2019 were selected by prospective randomized trial method,and divided into the control group(n=30)and the observation group(n=30)by the random number table method.The control group was treated with conventional RRTI continuing nursing,and the observation group was treated with remote continuing nursing on the basis of the control group,both with continuous intervention for 3 months.The nursing total satisfaction of the children′parents and their knowledge of disease were compared after 3 months of intervention.The recurrence rates and readmission rates were compared between the two groups after 1 year follow-up.Results The nursing satisfaction of parents in the observation group was higher than that of parents in the control group,and the difference was statistically significant(P＜0.05).The scores of parents′disease knowledge mastery in the observation group was higher than that of parents in the control group,and the difference was statistically significant(P＜0.05).Follow up for 1 year,the recurrence rate and readmission rate of children in the observation group were lower than those of children in the control group,and the differences were statistically significant(P＜0.05).Conclusion Remote continuing nursing intervention can improve parents'satisfaction and disease knowledge mastery score,and reduce the incidence and readmission rate of children with RRTI,which is a relatively effective nursing scheme.
		2021 Vol. 28 (14): 239-242 [Abstract] ( 44 ) HTML (32 KB) PDF (0 KB) ( 7 )

	243	A qualitative research on the experience of role transition of novice nurses in the context of standardized training
		XIAO Feng； SHI Sheng-ying；LI Shuang； REN Ying；SONG Hui-juan
		Objective To deeply understand the true feelings of novice nurses′role transformation under the background of standardized training,find out the blind spots in the training work,and provide the basis for formulating a more reasonable standardized training system.Methods By using purposive sampling method,twenty-seven novice nurses from two affiliated hospitals of Southern Medical University were recruited and semi-structured interviews were conducted from July to November 2019.The materials were analyzed by Colaizzi seven-step method.Results Four themes were extracted:The dilemma of the professional role in practice is diverse,the expectation of the professional role is inconsistent with the fact,the stable professional thought has not been formed,and actively adapt to professional role performance.Conclusion During the standardized training period,nursing managers should pay more attention to the characteristics of the role transition of novice nurses,take targeted measures to achieve the balance development of professional competence and cognition,promote the orderly completion of the role transition of novice nurses,and maintain the stability of the nursing team.
		2021 Vol. 28 (14): 243-246 [Abstract] ( 45 ) HTML (36 KB) PDF (0 KB) ( 6 )

	247	Application of holistic nursing intervention in vaginal trial of scar uterus repregnancy
		CHEN Li-mei； AI Hong-yun； LIN Yu-ting； LIANG Xiao-luan； LUO Jian-gang
		Objective To explore the application effect of holistic nursing intervention in vaginal trial of scar uterus repregnancy.Methods From July 2019 to August 2020,122 cases of obstetric women with scar uterus with second pregnancy vaginal trial were selected as study subjects.They were divided into the control group(n=61)and the observation group(n=61)by random number table method.Routine nursing intervention was carried out in the control group and overall nursing intervention was carried out in the observation group.The success rate of vaginal trial delivery,total labor,postpartum hemorrhage,length of hospital stay,and postpartum complications were compared between the two groups to investigate the satisfaction degree of parturients with nursing services.Results The success rate of vaginal trial production in the observation group(86.89%)was higher than that of the control group(63.93%),the difference was statistically significant(P＜0.05).In the observation group,the total labor was shorter than that of the control group,the amount of postpartum bleeding was less than that of the control group,the length of hospital stay was shorter than that of the control group,and the postpartum total complications were lower than that of the control group,with statistical differences(P＜0.05).The nursing total satisfaction of the observation group was 98.36%(60/61)higher than that of the control group of 83.61%(51/61),the difference was statistically significant(P＜0.05).Conclusion The application of holistic nursing intervention in vaginal trial labor of scar uterus repregnancy can improving the success rate of vaginal trial labor,shorting the total labor,reducing the amount of postpartum bleeding and complications,shorting the length of hospital stay,and improving the maternal satisfaction with nursing services.
		2021 Vol. 28 (14): 247-249转253 [Abstract] ( 44 ) HTML (32 KB) PDF (0 KB) ( 6 )

	250	Effect of comprehensive nursing intervention on quality of life of patients with breast benign tumor after Mammotome minimally invasive rotary resection
		AI Jian-jun
		Objective To explore the effect of comprehensive nursing intervention on the quality of life of patients with breast benign tumor after Mammotome minimally invasive rotary resection.Methods A total of 60 patients with benign breast tumor who were admitted to the Fuzhou Maternal and Child Health Hospital from January 2018 to June 2020 were selected as the research subjects.All patients were female and were divided into control group(30 cases)and observation group(30 cases)according to random number table method.The control group received routine nursing,while the observation group received comprehensive nursing.The quality of life(functional assessment of cancer therapygeneric[FACT-G]),negative emotions[Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD)]and patient care satisfaction were compared between the two groups before and 7 d after intervention.Results Before intervention,there were no significant differences in FACT-G,HAMA and HAMD scores between the two groups(P＞0.05).After the intervention,the FACT-G score of the two groups was higher than that before the intervention,while the scores of HAMA and HAMD were lower than those before the intervention,and the differences were statistically significant(P＜0.05).After intervention,the FACT-G score of the observation group was higher than that of the control group,while the scores of HAMA and HAMD were lower than that of the control group,the differences were statistically significant(P＜0.05).Nursing satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Comprehensive nursing intervention can improve the quality of life of patients with breast benign tumor after Mammotome minimally invasive rotary resection,improve the negative emotions of patients,so as to improve patient satisfaction.
		2021 Vol. 28 (14): 250-253 [Abstract] ( 41 ) HTML (31 KB) PDF (0 KB) ( 7 )

	254	Application value of evidence-based nursing in quality management of urological nursing
		XU Li-yuan； LIU Liu ；LI Liu-fang
		Objective To analyze the application value of evidence-based nursing in quality management of urologiy surgery.Methods A total of 66 urological inpatients admitted to Guangxin District People′s Hospital of Shangrao City in Jiangxi Province from January 2018 to January 2020 were selected as the study subjects.According to the random number table method,the patients were divided into the routine group(33 cases)and the evidence-based group(33 cases).The routine group was adopted the routine nursing mode,and the evidence-based group was adopted the evidence-based nursing mode.The emotional state,satisfaction degree,remission time of clinical symptoms,complications and nursing quality of the two groups were compared.Results The scores of anxiety assessment scale(SAS)and depression assessment scale(SDS)after nursing in the evidence-based group were lower than those in the routine group,the satisfaction score was higher than that in the routine group,the remission time of clinical symptoms was shorter than that in the routine group,the total incidence of complications was lower than that in the routine group,and the scores of various indicators of nursing quality were higher than that in the routine group,with statistical differences(P＜0.05).Conclusion The implementation of evidence-based nursing in the quality management of urological care has positive significance in improving patients′emotional state,promoting the remission of clinical symptoms,reducing the incidence of complications,improving the quality of care and nursing satisfaction.
		2021 Vol. 28 (14): 254-256 [Abstract] ( 38 ) HTML (30 KB) PDF (0 KB) ( 8 )

	257	Analysis of the effect of key indicators of blood donation service quality on retention of fixed blood donors
		GUAN Fei-shun； WU Lan
		Objective To explore the effect of key indicators of blood donation service quality on retention of fixed blood donors.Methods From June 2018 to June 2019,120 blood donors admitted to Guangzhou Blood Center,Guangdong Province were selected as the research objects.The random number table method was used to divide the blood donors into the reference group(60 cases)and the experimental group(60 cases).Among them,the reference group received routine nursing,and the experimental group received key indicator nursing.The conversion success rate,the success rate of one-time blood collection and the nursing satisfaction score of the two groups were observed.Results After nursing the first-time blood donors,the conversion success rate and one-time blood sampling success rate of the experimental group were higher than those in the reference group,the nursing satisfaction score of the experimental group was higher than that of the reference group,the differences were statistically significant(P＜0.05).Conclusion In the nursing of primary blood donors,the key index nursing of blood donation service quality can improve the success rate of transformation of fixed blood donors,improve the quality of nursing and provide safety and security for blood donors.To provide effective help for clinical blood use,has the promotion value.
		2021 Vol. 28 (14): 257-259 [Abstract] ( 36 ) HTML (29 KB) PDF (0 KB) ( 7 )

	260	Application of SBAR communication mode in emergency ICU patients transfer
		LIANG Tian-ying；DENG Xiao-yun
		Objective To explore the application of SBAR communication mode in the transfer and handover of emergency ICU patients.Methods A total of 80 cases of critically ill patients with emergency ICU transfer handover in Zhongshan Southern District Hospital in Guangdong Province from March 2019 to July 2020 were selected and divided into the observation group(40 cases)and the control group(40 cases)according to the random number table method.The control group was transferred by oral handover and filling in the ordinary handover form;the transfer handover was observed by SBAR communication mode,and the handover effect of the two groups was compared.Results The total incidence of adverse nursing events in the observation group was 7.50%,lower than 25.00% in the control group,and the difference was statistically significant(P＜0.05）.The incidence of unclear nurse handover problems in the observation group was 5.00%,lower than 27.50% in the control group,and the difference was statistically significant(P＜0.05).The patients′total satisfaction with nursing in the observation group was 97.5%,higher than that of the control group of 60.00%,the difference was statistically significant(P＜0.05).The average transfer time of the observation group was(4.18±0.51)min shorter than the control group of(12.01±0.70)min，the difference was statistically significant(t=57.178,P＜0.05).Conclusion The application of SBAR in the transfer of patients can reduce the incidence of adverse events and reduce the incidence of adverse events.
		2021 Vol. 28 (14): 260-263 [Abstract] ( 55 ) HTML (32 KB) PDF (0 KB) ( 7 )

	264	Influence of family-centered integrated delivery room model on maternal delivery mode and maternal and infant outcome
		HUANG Mu-lan
		Objective To explore the application effect of family-centered integrated delivery room model in parturients.Methods A total of 82 parturients who gave birth in Jiangmen Maternal and Child Health Hospital in Guangdong Province from May 2018 to April 2020 were selected.They were divided into the observation group and the control group according to the random number table method,41 cases in each group.In the control group,traditional delivery room model was used,and in the observation group,family-centered integrated delivery room model was provided.The delivery mode,maternal and infant outcomes,psychological status and quality of life were compared in the two groups.Results The natural delivery rate in the observation group was 95.12%,higher than that in the control group accounting for 65.85%,the incidence of postpartum hemorrhage in the observation group was 9.76%,lower than that in the control group accounting for 48.76%,the incidence of neonatal asphyxia in the observation group was 0.00%,lower than that of the control group accounting for 17.07%,and the differences were statistically significant(P＜0.05).The self-rating anxiety scale(SAS)and self-rating depression scale(SDS)scores of the observation group were(42.56±3.88)and(45.15±3.28)points,respectively,lower than those of the control group of(47.15±3.96)and(50.60±3.74)points,and the differences were statistically significant(P＜0.05).The scores of mental state,appetite,sleep,daily life and society function in the observation group were(3.31±0.17)points,(3.23±0.15),(3.33±0.19),(3.05±0.18),and(3.32±0.18)points,all higher than those of the control group,(2.19±0.13),(2.39±0.19),(2.22±0.21),(2.18±0.17),，and(2.35±0.19)points,respectively,the differences mentioned above all differed statistically(P＜0.05).Conclusion The family-centered integrated delivery room model can improve the maternal mental state,increase the rate of natural delivery,reduce the incidence of adverse maternal and infant outcomes,and ameliorate the quality of life.
		2021 Vol. 28 (14): 264-266 [Abstract] ( 39 ) HTML (30 KB) PDF (0 KB) ( 6 )

	267	Application of cluster nursing in patients with acute respiratory distress syndrome prone mechanical ventilation
		CHEN Xiao-li； WANG Ya-hua ；CHEN Yun-feng
		Objective To explore the application of cluster nursing in patients with acute respiratory distress syndrome(ARDS)prone mechanical ventilation.Methods From May 2019 to May 2020,60 patients with ARDS who were treated with prone mechanical ventilation in the Affiliated Hospital of Jiujiang University were selected and divided into the control group(30 cases)and the observation group(30 cases)according to the random number table method.The control group implemented routine nursing intervention,and the observation group implemented clustered nursing intervention on the basis of the control group.Both interventions were for 1 month.Compare the blood gas indexes of the two groups before and after the intervention(intervention for 1 month);record and compare the hospital stay of the two groups;statistically compare the cumulative number of unplanned extubation and the total incidence of complications during the intervention of the two groups.Results After the intervention,the oxygenation index(PaO2/FiO2)levels of the two groups were higher than those before the intervention,and the observation group was higher than the control group,the differences were statistically significant(P＜0.05).The observation group′s hospital stay was shorter than the control group,the cumulative number of unplanned extubation during the intervention period was less than that in the control group,and the differences were statistically significant(P＜0.05).During the intervention period,the total complication rate of the observation group was compared with the control group,and the difference was not statistically significant(P＞0.05).Conclusion The effect of clustered nursing in patients with ARDS prone mechanical ventilation is more significant,and it is effective in improving patients′blood gas indicators,shortening the hospital stay,and reducing the cumulative number of unplanned extubations.
		2021 Vol. 28 (14): 267-269转273 [Abstract] ( 45 ) HTML (32 KB) PDF (0 KB) ( 6 )

	270	Application effect of comprehensive nursing intervention in patients with liver cirrhosis complicated with upper gastrointestinal bleeding
		CHEN Shu-jin
		Objective To explore the application effect of comprehensive nursing intervention in patients with liver cirrhosis complicated with upper gastrointestinal bleeding.Methods From October 2018 to October 2019,64 patients with liver cirrhosis complicated with upper gastrointestinal bleeding treated in Putian First Hospital,Fujian province were selected as observation objects,and were divided into the control group and the observation group according to the order of admission method,with 32 cases in each group.Patients in control group were given routine nursing intervention,while patients in observation group were given comprehensive nursing intervention on the basis of control group.The treatment compliance,self-management ability assessment scale(AHSMRS)and general self-efficacy scale(AHSMRS)before and after intervention were observed.Results The treatment compliance of patients in the observation group was 93.75%,higher than that in the control group of 59.37%,the difference was statistically significant(P＜0.05).After different nursing interventions,the scores of self-management cognition,self-management behavior,self-management environment and GSES scale in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).The clinical cure rate was 84.38% in observation group which was higher than that in control group of 59.38%,the difference was statistically significant(P＜0.05).Conclusion Comprehensive nursing intervention can improve patients'treatment compliance and self-care ability,and improve patients′clinical cure rate which has remarkable effect and is worth popularizing.
		2021 Vol. 28 (14): 270-273 [Abstract] ( 46 ) HTML (31 KB) PDF (0 KB) ( 7 )

	274	Application of detailed nursing in hepatitis complicated with diabetes mellitus
		HE Ming-yi； WANG Jun ；LIU Ying-ying
		Objective To evaluate the value of detailed nursing intervention in the nursing of hepatitis complicated with diabetes mellitus(DM).Methods A total of Sixty patients with hepatitis and DM who treated in Dalian Sixth People′Hospital,Liaoning Province from January 2015 to January 2019 were selected as the research subjects.They were divided into the control group and the experimental group by drawing lottery method,wit 30 cases in each group.In the control group,regular routine nursing was used,and in the experimental group,detailed nursing intervention with specific nursing measures was adopted.The blood glucose control and liver function indicators of the two groups were compared.Results The fasting blood glucose(FPG),2-hour postprandial blood glucose(2 h PG)and glycosylated hemoglobin(HbA1c)before nursing of the two groups were compared,the difference had no statistical significance(P＞0.05).The FPG of the experimental group after nursing was(6.2±1.4)mmol/L,the 2 h PG was(7.4±1.5)mmol/L,and the HbA1c was(5.9±1.0)%;the FPG of the control group after nursing was(8.2±1.6)mmol/L,2 h PG was(10.2±1.4)mmol/L,and HbA1c was(8.1±1.6)%.The FPG,2 h PG,and HbA1c of the experimental group after nursing were lower than those of the control group,and the differences were statistically significant(P＜0.05).The aspartate aminotransferase(AST),the alanine aminotransferase(ALT),total bilirubin(TBil),and albumin(ALB)before nursing of the two groups were compared,;the difference had no statistical significance(P＞0.05).After nursing,the AST of the experimental group was(52.2±18.3)U/L,ALT was(45.7±17.5)U/L,TBil was(20.6±9.9)μmol/L,and ALB was(43.3±4.4)g/L.After nursing,the AST of the control group was(77.7±17.6)U/L,ALT was(78.8±18.2)U/L,TBil was(38.7±9.6)μmol/L,and ALB was(40.2±4.8)g/L.After nursing,the AST,ALT and TBil of the experimental group were lower than those of the control group,and the ALB was higher than that of the control group,with statistical differences(P＜0.05).Conclusion In nursing hepatitis patients combining with DM,detailed nursing intervention can help control blood glucose,remarkably improve liver function as well as the quality of life,which can be widely used in clinical practice.
		2021 Vol. 28 (14): 274-276 [Abstract] ( 43 ) HTML (30 KB) PDF (0 KB) ( 6 )

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