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| Research on the value of Conjugated Estrogen Cream combined with Misoprostol in ring removal after menopause |
| ZHOU Juan-juan |
| Department of Obstetrics and Gynecology,Xishan People′s Hospital,Jiangsu Province,Wuxi 214105,China |
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Abstract Objective To analyze the value of Conjugated Estrogen Cream combined with Misoprostol in ring removal after menopause.Methods A total of 80 postmenopausal patients who were treated in Xishan People′s Hospital from January 2017 to January 2020 were divided into control group(n=40)and observation group(n=40)according to random number table method.The control group were given Misoprostol 400 μg anal plug 1 h before operation,and the observation group was given 1 g of Conjugated Estregen Cream for vaginal medication for 1 week every day,and Misoprostol 400 μg anal plug 1 hour before operation.The visual analogue scores of the intraoperative dilation process,intraoperative blood loss,time of ring removal,total effective rate of cervical dilation,success rate of ring removal,and adverse reactions were compared between the two groups.Results The visual simulation score of intraoperative dilation of the observation group was lower than that of the control group,the amount of intraoperative blood loss was less than that of the control group,and the ring removal time was shorter than that of the control group,the differences were statistically significant(P＜0.05).The total effective rate of cervical dilation and the success rate of ring removal were higher than those of the control group,the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Conjugated Estrogen Cream combined with Misoprostol has a high value in the application of postmenopausal ring removal.Conjugated Estrogen Cream is simple and convenient for vaginal administration,and the amount of Estrogen is small.It can effectively dilate the cervix,shorten the time of ring removal,reduce bleeding and improve the success rate of ring removal,and alleviate the pain of patients,which is worthy of promotion.
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