经硬质支气管镜下冷冻肺活检对外周肺结节的诊断价值

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Abstract Objective To investigate the diagnostic rate and safety of frozen lung biopsy under rigid bronchoscope for peripheral pulmonary nodules.Methods A retrospective analysis was performed on 42 patients who received frozen lung biopsy under rigid bronchoscope of peripheral pulmonary nodules(8 mm＜maximum diameter of nodules≤30 mm)admitted to the Second Affiliated Hospital of Xiamen Medical University from November 2017 to February 2019.Patients were divided into group A(8 mm＜nodule diameter≤20 mm,n=18)and group B(20 mm＜nodule diameter≤30 mm,n=24)according to the size of nodule.All patients underwent frozen lung biopsy under rigid bronchoscope.The positive rate of malignant tumor and complications were compared between the two groups.Results The positive and negative rates of malignant tumors in group A were 55.5%(10/18)and 44.5%(8/18),respectively.The positive and negative rates of malignant tumors in group B were 87.5%(21/24)and 12.5%(3/24),respectively.The positive rate of malignant tumor diagnosis in group B was higher than that in group A,the difference was statistically significant(χ2=3.903,P=0.048).There was no significant difference in the incidence of bleeding and pneumothorax between the two groups(P＞0.05).Patients in both groups were discharged successfully after active treatment.Conclusion Frozen lung biopsy under rigid bronchoscope has a high positive rate for the diagnosis of peripheral pulmonary nodules,especially for patients with peripheral pulmonary nodules with nodule diameter＞20 mm to≤30 mm that the positive rate of malignant tumor diagnosis can reach 87.5%,and the incidence of bleeding and pneumothorax in patients with different nodule diameters is relatively low,which is safe.

Key words： Frozen lung biopsy Pulmonary nodules Rigid bronchoscope Diagnostic value

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	Articles by authors
	HUANG Rui
	YONG Ya-zhi
	ZENG Jun-li
	CHEN Zhi-de

Cite this article:

HUANG Rui,YONG Ya-zhi,ZENG Jun-li, et al. Diagnostic value of frozen lung biopsy under rigid bronchoscope for peripheral pulmonary nodules[J]. 中国当代医药, 2021, 28(14): 27-30.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I14/27

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