肾动脉阻力指数对2型糖尿病患者经皮冠脉介入术后造影剂致急性肾损伤的预测价值

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (35 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the predictive value of renal artery resistance index(RRI)on contrast-induced acute kidney injury(CI-AKI)in patients with type 2 diabetes mellitus(T2DM)after percutaneous coronary intervention(PCI).Methods A total of 100 cases of T2DM patients who underwent PCI treatment in Pingxiang People′s Hospital from January 2020 to September 2020 were selected as the research objects.According to CI-AKI diagnostic criteria,they were divided into a CI-AKI group(n=30)and a non-CI-AKI group(n=70).The baseline data,serum creatinine(Scr)levels and RRI between the two groups were compared,and the influencing factors of CI-AKI in patients with T2DM after PCI were analyzed,the receiver operating characteristic(ROC)curve was drawn to judge the value of contrast agent dose,peak systolic velocity(PSV)of renal artery,end diastolic velocity(EDV),Scr levels and RRI in the detection of CI-AKI.Results The results of univariate analysis showed that there were statistical significant differences in compared contrast dose,PSV and EDV between CI-AKI group and non CI-AKI group(P＜0.05);the levels of Scr at 24 h and 48 h after operation and RRI at 24 h after operation in CI-AKI group were higher than those in non CI-AKI group(P＜0.05);the results of Logistic multivariate analysis showed that the dose of contrast medium(β=0.048,OR=1.050,95%CI=1.031-1.069),PSV(β=-0.301,OR=0.832,95%CI=0.803-0.982),EDV(β=-0.356,OR=0.625,95%CI=0.531-0.878),Scr level(β=0.063,OR=1.065,95%CI=1.042-1.090),RRI(β=2.999,OR=20.063,95%CI=1.204-334.228)were the related influenccing factors of CI-AKI in T2DM patients after PCI(P＜0.05).ROC curve was drawn,and the results showed that contrast agent dose,PSV,EDV,Scr,RRI detected the area under the curve(AUC)of patients with T2DM after PCI were 0.880,0.928,0.971,0.878 and 0.925,respectively,the sensitivity of each index were 97.0%,97.1%,95.7%,98.6% and 97.2% respectively,all higher than 90.0%,but the specificity of RRI was the highest(96.7%),therefore,the predictive value of RRI in detection of CI-AKI was higher.Conclusion Higher dose of contrast agent,PSV,EDV,Scr level and RRI are the influencing factors for the occurrence of CI-AKI after PCI in T2DM patients,among them,RRI can better predict CI-AKI.Early detection of RRI has important value for the early diagnosis and clinical diagnosis and treatment of CI-AKI after PCI treatment for T2DM.

Key words： Type 2 diabetes mellitus Percutaneous coronary intervention Contrast-induced acute kidney injury Renal artery resistance index

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI Jiao
	LUO Qin
	YANG Zhao
	YI Yong-zhong

Cite this article:

LI Jiao,LUO Qin,YANG Zhao, et al. Predictive value of renal artery resistance index on contrast-induced acute kidney injury in patients with type 2 diabetes mellitus after percutaneous coronary intervention[J]. 中国当代医药, 2021, 28(14): 147-150.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I14/147

[1]	翟文亮，王长远，王晶，等.重症病房老年糖尿病患者脓毒症相关急性肾损伤的发生及预后[J].医学综述，2017，23（19）：3938-3941.
[2]	施超，周玉杰，秦政，等.急性冠状动脉综合征合并糖尿病患者急诊经皮冠状动脉介入术后对比剂急性肾损伤的危险因素分析[J].心肺血管病杂志，2018，37（5）：393-397.
[3]	Vlachopanos G，Schizas D，Hasemaki N，et al.Pathophysiology of Contrast-Induced Acute Kidney Injury（CIAKI）[J].Curr Pharm Des，2019，25（44）：4642-4647.
[4]	武钧，许志伟，张泓，等.肾血管阻力指数对重症急性胰腺炎相关性急性肾损伤早期预测价值的临床研究[J].中华危重病急救医学，2019，31（8）：998-1003.
[5]	冠心病介入诊疗对比剂应用专家共识组.冠心病介入诊疗对比剂应用专家共识[J].中国心血管病研究，2010，8（12）：881-889.
[6]	中华医学会糖尿病学分会.中国2型糖尿病防治指南（2017年版）[J].中国实用内科杂志，2018，38（4）：292-344.
[7]	马丽娅，李震，沈亚琪，等.碘对比剂相关急性肾损伤及相关危险因素的大样本回顾性研究[J].放射学实践，2018，33（9）：918-922.
[8]	王海霞，张春.对比剂急性肾损伤早期预测生物学标志物研究进展[J].中国循证心血管医学杂志，2018，10（8）：111-113.
[9]	苗晓云，回志，代庆春，等.血胱抑素C、尿肾损伤分子-1水平和血清肌酐在急性肾损伤患者肾功能评估中的比较研究[J].中国中西医结合肾病杂志，2017，18（8）：710-712.
[10]	王伟，刘维军.造影剂急性肾损伤最新检测手段及预防措施研究进展[J].中华老年心脑血管病杂志，2019，21（1）：99-102.
[11]	李彦飞，任克.糖尿病基础上对比剂诱导急性肾损伤发生机制研究进展[J].中国介入影像与治疗学，2020，17（1）：55-59.
[12]	李华，高月花，贾化平，等.急性肾损伤肾脏超声造影的初步临床研究[J].中国超声医学杂志，2017，33（6）：533-536.
[13]	陈骥，伍海斌，孙小聪，等.肾动脉阻力指数对脓毒症相关性急性肾损伤可逆性诊断的预测价值[J].广东医学，2019，40（13）：1971-1973.
[14]	赵鹏，刘星，孟祥安，等.超声测定肾动脉阻力指数在脓毒症合并急性肾损伤患者中的作用[J].湖南师范大学学报（医学版），2018，15（3）：116-119.
[15]	Zhang W，Zhang J，Yang B，et al.Effectiveness of oral hydration in preventing contrast-induced acute kidney injury in patients undergoing coronary angiography or intervention：a pairwise and network meta-analysis[J].Coron Artery Dis，2018，29（4）：286-293.