Home                              中文

Forthcoming Articles Current Issue Archive Advanced Search Read Articles Download Articles Email Alert

Quick Search     Adv Search 2018 Vol. 25, No. 25 Published: 2018-09-08   4 Mental resilience level and its influencing factors in senile dementia patients YANG Jia-min;ZHANG Dong-ying;LIU Hua Objective To understand the mental resilience level in senile dementia patients and analyze its influencing factors.Methods The Chinese version of Connor Davidson Resilience Scale (CD-RISC)and Social Support Rating Scale (SSRS)were used to investigate the mental resilience and social support of 96 senile dementia patients in the cadre health outpatient and inpatient departments from January to October in 2017.Results The mental resilience score of Alzheimer′s patients was(25.30±5.757)points,which was positive correlation with the total score of social support(r=0.661,P＜0.01).The course of disease,self-care ability and objective support of Alzheimer′s patients were the factors affecting the mental resilience of Alzheimer′s patients,and 49.8%of the mental resilience of Alzheimer′s patients was explained.Conclusion The mental resilience level of Alzheimer′s patients is in the middle level.The course of disease,self-care ability and objective support are the factors affecting the mental resilience of the Alzheimer′s patients.It suggests that the medical staff should carry out the targeted psychological guidance from the above aspects and encourage them to respond to the disease in a positive way so as to improve the patients′resilience and improve their quality of life. 2018 Vol. 25 (25): 4-07 [Abstract] ( 145 ) HTML (40 KB)  PDF  (0 KB)  ( 32 ) 8 Study on the regulation of urinary calcium resorption by TRPV5 signaling pathway CHEN Zhong-ping;LIN Jun;WANG Qun;FANG Chen;DING Li;CHEN Zhong;YAN Wei-zhi Objective To discuss how the TRPV5 signaling pathway regulates the reabsorption of urinary calcium,thus affecting the concentration of urinary calcium and thereby affecting the formation of calcium-containing kidney stones.Methods The twenty SD rats were randomly selected to take ten into the stone group,the others into the control group.After the success of the model building,the determination of 24 hours urinary calcium concentration in rats,and the expression of TRPV5 and its mRNA in rat kidney were detected by immunohistochemical and quantitative real time PCR.Results It was found that urinary calcine concentration of 24 hour in the stone group was significantly higher than that in the control group,the difference was statistically significant(P＜0.01).The expression of TRPV5 protein and its mRNA in the stone group were lower than in the control group,the difference was statistically significant(P＜0.01).Conclusion The decrease of TRPV5 expression or lack of TRPV5 can reduce the reabsorption of calcium in renal tubules and promote the formation of calcium kidney stones. 2018 Vol. 25 (25): 8-10转15 [Abstract] ( 144 ) HTML (36 KB)  PDF  (0 KB)  ( 5 ) 11 Study on the alcohol precipitation and drying process of Shiwei Ehuang Granules ZHU Zhi-de;LUO Yu-dong; XIAO Ming;TAN An-qiang;LI Fang-chan Objective To optimize the alcohol precipitation and drying process of Shiwei Ehuang Granules.Methods Taken the content of Astragaloside A in Shiwei Ehuang Granules as the indexes,the orthogonal design was used to examine the effect of four factors(relative density of the ointment,added alcohol concentration,alcohol precipitation content and standing time after alcohol precipitation)on the alcohol precipitation process of the product,so as to determine the best process of alcohol precipitation for Shiwei Ehuang Granules.The effect of different drying methods and temperature on the content of Astragaloside A in dry ointment was studied to determine the best drying process for the product.Results The optimal alcohol precipitation process of Shiwei Ehuang Granules was as follows:1.10-1.15(80°C)relative density of ointment,adding 95%alcohol to make alcohol content 70%,and 12 h alcohol precipitation time.The optimal drying process of Shiwei Ehuang Granules was decompression drying,and the drying temperature was 85℃.The average content of Astragaloside A in three batches of products according to above optimized alcohol precipitation and drying process was 5.48 mg/g,and RSD was 1.74% (n=3).Conclusion Shiwei Ehuang Granules produced according to the optimized alcohol precipitation and drying process contain the effective components corresponding to the prescription,whose quality is stable and suitable for mass production.Therefore,the process is reasonable and feasible. 2018 Vol. 25 (25): 11-15 [Abstract] ( 155 ) HTML (45 KB)  PDF  (0 KB)  ( 29 ) 16 Influence of Caffeic Acid on blood glucose concentration in rats with type 2 diabetes mellitus PEI Yu;DONG Xu;TANG Xin-yi;HE Ai-hua;YANG Hao;ZHOU Hong;ZHOU Jian-zhong;LI Hua-nan Objective To explore the influence of Caffeic Acid on blood glucose concentration in rats with type 2 diabetes mellitus.Methods Sixty male SD rats aged 6-8 weeks were selected and fed for 3 days.Twenty rats were selected as the normal observation group and they were divided into the blank group and experimental group1-3,and there were 5 rats in each group.The experimental group 1～3 was fed with 0.4,0.6 and 0.8 g/kg of Caffeic Acid respectively,the blank group was gavaged with 1 ml/100 g of equivalent distilled water.The other 40 rats were fed with high-sugar and high-fat diet for 6 weeks and intraperitoneally injected with 30 mg/kg Streptozotocin(STZ)for 3 days,the model of type 2 diabetic rats was established,FPG>7 mmol/L and rat urine sugar test positive were considered to be successful in modeling.Thirty rats successfully modeled were randomly divided into model group,Acarbose group,combined group and Caffeic Acid group 1-3,and there were 5 rats in each group.Acarbose group was given 10 mg/kg Acarbose,combined group was given 10 mg/kg of Acarbose and 1 g/kg of Caffeic Acid,Caffeic Acid group 1-3 was given 0.8,1.0,1.2 g/kg respectively,model group was given 1 ml/100 g of distilled water.The influence of Caffeic Acid on fasting blood glucose(FPG)and insulin(INS)in rats of normal observation group was observed at different times;the influence of each drug group on the concentration of FPG in type 2 diabetic rats was observed.Results There was no significant difference in FPG concentration and INS expression level among the groups (in normal observation group)before gavage,gavage for the first,sixth day(P>0.05).There was no significant difference in FPG concentration among the groups(in model group and various drug group)before gavage(P>0.05).After gavage,compared with model group,the FPG concentration in various drug group were decreased significantly,and the differences were statistically significant(P＜0.05,P＜0.01).The FPG concentration in combined group was significantly lower,and the difference was statistically significant(P＜0.01).Among the drug groups,the combined group had the most significant hypoglycemic effect(P＜0.05).Conclusion Caffeic Acid has a reducing FPG effect on type 2 diabetic rats,but it is not as effective as Acarbose in reducing blood sugar.The effect of Acarbose combined with Caffeic Acid was the most obvious. 2018 Vol. 25 (25): 16-18转22 [Abstract] ( 160 ) HTML (39 KB)  PDF  (0 KB)  ( 25 ) 19 Relationship study of gas signal conducting molecules and mild Rotavirus enteritis accompanied with benign convulsions in infants CHEN Rui-dan;LI Na;MU Ya-ping; WANG Shuang;LI Lun Objective To explore the relationship between the change of nitric oxide(NO),nitric oxide synthase(NOS)and hydrogen sulfide (H2S)level in infants with mild Rotavirus enteritis accompanied with benign convulsions.Methods A total of 50 children diagnosed as mild Rotavirus enteritis accompanied with benign convulsion in Shenyang Children′s Hospital from September 2015 to April 2017 were selected as the observation group in Shenyang Children′s Hospital,and 50 children with simple mild Rotavirus enteritis were selected as the control group at the same time.The clinical features,routine laboratory tests,and NO,NOS,H2S changes in children of the two groups and convulsion characteristics of the observation group were observed.Results There was no significant difference in clinical characteristics,routine laboratory examination and NO level between the two groups(P＞0.05).The serum NOS level of the observation group was significantly higher than that of the control group,and the serum H2S level was significantly lower than that of the control group(P＜0.01).Conclusion The occurrence of mild rotavirus enteritis with benign convulsion is independent of NO level,and is related to NOS and H2S level,and it suggests that the incidence of benign convulsions in children with mild Rotavirus enteritis can be predicted by changes in serum NOS and H2S level. 2018 Vol. 25 (25): 19-22 [Abstract] ( 143 ) HTML (44 KB)  PDF  (0 KB)  ( 36 ) 23 Comparative effects of neuromuscular electrical stimulation and respiratory muscle training in post-stroke dysphagia YANG Hong-ying;XUE Xiao-qin;CHEN Yu Objective To observe the effects of comprehensive treatments of neuromuscular electrical stimulation（NMES） and respiratory muscle training on the swallowing function in post-stroke dysphagia.Methods A total of forty six patients with dysphagia after stroke treated in our hospital from October 2016 to January 2018 were selected as the subjects,and divided into control group(16 cases),respiratory training treatment group(15 cases)and NMES treatment group (15 cases)by random number table method.The control group received conventional swallowing training,while the respiratory training treatment group received breathing training and NMES group received neuromuscular electrical stimulation treatment on basis of the conventional swallowing training,they were treated for 4 weeks.Before and after treatment,the Kubota drinking water test(KDWT)and the Chinese eating assessment tool(EAT-10)were assessed,and the clinical effects were compared.Results The effectiveness rate of KDWT in the NMES treatment group(73.3%)was higher than that in the respiratory training group (60.0%),the difference was statistically significant(P＜0.05).After treatments,the EAT-10 scores were decreaced in the three groups,and the EAT-10 score in the NMES treatment group was significant lower than that in the respiratory training group and the control group,the differences were statistically significant(P＜0.05).Conclusion NMES treatment combined with swallowing rehabilitation training is superior for improving the swallowing function of post-stroke dysphagia patients. 2018 Vol. 25 (25): 23-26 [Abstract] ( 130 ) HTML (42 KB)  PDF  (0 KB)  ( 31 ) 27 Clinical observation and prognosis analysis of elderly patients with acute leukemia combined with type 2 diabetes mellitus HE Ji-xiang;JIANG Yi-rong Objective To explore the clinical features and prognosis of elderly patients with acute leukemia combined with type 2 diabetes mellitus.Methods A total of 35 elderly patients with acute leukemia combine with type 2 diabetes mellitus were treated in our hospital from January 2014 to December 2016 were selected and retrospectively analyzed.According to the blood glucose status during diagnosis and treatment,they were divided into the observation group (n=12,high blood glucose or fluctuating state)and control group(n=23,good blood glucose control).The fasting blood glucose (FBG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),triglyceride(TG)and serum uric acid(UA)and other diabetes mellitus related indexes during chemotherapy were compared between the two groups,and the difference of treatment effect,adverse reactions and long-term survival time were analyzed.Results The levels of FBG,TC,LDL-C and UA in the control group were lower than those in the observation group during chemotherapy,and the differences were statistically significant(P＜0.05),while there was no significant difference in the levels of HDL-C and TG between the two groups(P＞0.05).The effective rate of the control group(91.30%)was higher than that of the observation group(41.67%)(P＜0.05).Adverse reactions mainly included ketoacidosis,infection,nervous system symptoms,digestive system symptoms and leukopenia.The incidence of ketoacidosis(0.00%),infection(30.43%)and digestive system symptoms(13.04%)in the control group was lower than those in the observation group(25.00%,66.67%,50.00%)respectively,and the difference was statistically significant(P＜0.05).There were no significant difference in the incidence of other adverse reactions between the two groups(P＞0.05).The median survival time in the control group(13.5 months)was longer than that in the observation group(6.75 months)(P＜0.05).Conclusion The elderly patients with acute leukemia combined with type 2 diabetes should be paid attention to reduce blood glucose treatment,the patients with poor glycemic control have the characteristics of poor curative effect,high infection rate and poor prognosis. 2018 Vol. 25 (25): 27-30 [Abstract] ( 159 ) HTML (44 KB)  PDF  (0 KB)  ( 23 ) 31 Research progress of thermosensitive liposomes as a tumor-targeting drug delivery carrier ZHU Xia-li;LI Ling-hua;HUANG He-qing;TIAN Xiao-zhi;JIA Yong-yan Thermosensitive liposome is a new targeted drug carrier.The thermosensitive liposome is used as a carrier to encapsulate an anti-tumor drug,which can be distributed to tumor tissues on targeting by utilizing an enhanced permeability and retention effect of the tumor tissue.After that,the drugs in the carrier will be released into tumor tissues once triggered by local external heating,which can improve the drug targeting,reduce systemic side effects,and achieve combined therapy of tumor thermochemotherapy.In this research,the related literature at home and abroad in recent years and the studies of thermosensitive liposomes as tumor-targeted drug delivery carriers were reviewed.As a tumor-targeted drug carrier,thermosensitive liposome has a good prospect. 2018 Vol. 25 (25): 31-34 [Abstract] ( 161 ) HTML (46 KB)  PDF  (0 KB)  ( 20 ) 35 Application progress of Seminar teaching method in nursing undergraduate education HU Li-ping;GOU Yu-li;SHA Li-yan The reform of nursing education has been a hot topic of current research.Since the Seminar teaching method was introduced to the classroom in China,the researchers have been keeping trying and innovating a lot.However,it is still necessary to further explore the development path suitable for the status quo of nursing education in China.The application situation,the innovative mode and the problem of Seminar at home and abroad are overviewed in this research,aiming at summing up the experience and putting forward the suggestion to solve the problem,so as to find a suitable mode for the domestic development of nursing science and to meet the social demand for nursing personnel. 2018 Vol. 25 (25): 35-38 [Abstract] ( 148 ) HTML (49 KB)  PDF  (0 KB)  ( 24 ) 39 Research progress on blood lipid management in type 2 diabetic patients CHENG Li;SHI Xiang Diabetes is an independent risk factor for cardio-cerebrovascular disease,and cardio-cerebrovascular disease is the main cause of complications and death in diabetic patients.Lipogenic treatment can significantly reduce the risk of cardiovascular events in diabetic patients and benefit patients with type 2 diabetes.By consulting the guidelines for the prevention and treatment of type 2 diabetes in China,Europe and the United States,the guidelines for the prevention and treatment of abnormal blood lipids,and some clinical experiments,the research in detail describes some questions like whether or not patients with type 2 diabetes need to start lipid-regulating treatment,when they need to start lipid-regulating treatment,and setting the target value of lipid-regulating,which type of lipid-regulating agent,the dose of the drug,and whether it is necessary to continue to use Statins after the blood lipids are up to the standard,etc.Through the study,the management of patients with type 2 diabetes is further understood. 2018 Vol. 25 (25): 39-42 [Abstract] ( 161 ) HTML (43 KB)  PDF  (0 KB)  ( 24 ) 43 Research advance of Th22 cell and its effectors in the role of autoimmunol dermatal diseases XU Xin-xin;SUN Qi-le;WANG Yi-ting;WANG Zhong-yong Th22 cells are the newly discovery of CD4+T cell subsets in recent years.They can secrete interleukin-22(IL-22),tumor necrosis factor(TNF-α)and a small amount of interleukin-13(IL-13)and interleukin-26(IL-20)and can express CCR6+,CCR4+and CCR10+in CC chemokine receptor(CCR),which are closely to the pathophysiology and homeostasis of the skin.In recent years,some studies have found that the expression level of Th22 cells in some skin diseases,especially in autoimmune dermatal diseases and their different development stages are significantly different,which suggests that Th22 cells may be closely related to the degree of disease activity,indicating that they may play a crucial role in immune dermatosis.The research reviews recent advances in the level of expression of Th22 cells in autoimmune dermatoses,so as to provide a theoretical basis for their role in this type of dermatology and also provide new ideas and insights for clear understanding of the pathogenesis and effective treatment of related diseases. 2018 Vol. 25 (25): 43-46 [Abstract] ( 181 ) HTML (45 KB)  PDF  (0 KB)  ( 23 ) 47 Discussion on surgical timing in patients with jaw fracture complicated with craniocerebral injury ZENG Zhi-mei;DING Guan-fu;LIU Ke-hua Objective To explore the surgical timing of jaw fracture complicated with craniocerebral injury.Methods A total of 80 patients with jaw fracture complicated with craniocerebral injury admitted into our hospital from June 2016 to December 2017 were selected.In the case of informed consent of the patients and after the consultation of doctors held by the neurosurgery department,anesthesiology department combined with the oral and maxillofacial surgery dpartment,according to the patients′vital signs and whether they can tolerate surgery and anesthesia,the patients were assigned into the same period surgery group,the early surgery group,and the delayed surgery group.The occlusal relationship,mouth opening degree and other indicators 1 month after operation,and GCS score change,blood routine and liver and kidney function indicators 1 week after operation in patients were analyzed.Results The normal rate of occlusal relationship in the same period surgery group was higher than that in the early surgery group and the delayed surgery group,the malocclusion rate and the limited rate of mouth opening of the same surgery period group were lower than those in the early surgery group and the delayed surgery group(P＜0.05).There was no significant difference in the positive rate of GCS score,blood routine test and abnormal liver and kidney function indicators among the three groups(P＞0.05).Conclusion If patients with jaw fracture and craniocerebral injury have stable vital signs and can tolerate surgery and anesthesia,and they can be given the reduction or fixation of jaw fracture at the same time or early stage. 2018 Vol. 25 (25): 47-49 [Abstract] ( 145 ) HTML (37 KB)  PDF  (0 KB)  ( 24 ) 50 Analysis of flora in type 2 diabetes mellitus complicated with lower respiratory tract infection WANG Tong;XIANG Hua-guo;LIN Yu-ping;ZHAO Ya-li;GAO Dan Objective To explore the flora characteristics of type 2 diabetes mellitus combined with lower respiratory tract infection.Methods A total of 120 patients with type 2 diabetes mellitus complicated with lower respiratory tract infection treated in our hospital from January 2015 to December 2017 were selected,and the identification and drug sensitivity test in 398 strains isolated from sputum of these patients were conducted using a Microscan Autoscan-4 microbiological analyzer.Results A total of 100 patients in 120 patients were positive in bacterial culture,and the positive rate of 83.33%(100/120).A total of 398 strains were isolated from sputum samples in 100 patients with positive bacterial culture,among them,367 strains were Gram-negative strains(accounting for 92.21%),and 31 strains were Grampositive strains(accounting for 7.79%).Stenotrophomonas maltophilia was naturally resistant to Imipenem.The resistance rate of the other 4 Gram-negative bacteria to Imipenem was 2.33%-15.3%.The detection rate of extended-spectrum beta-Lactamases(ESBLs)producing Escherichia coli,Klebsiella pneumoniae,methicillin-resistant Staphylococcus aureus(MRSA),multidrug-resistant Pseudomonas aeruginosa (MDR-PA)and multidrug-resistant Acinetobacter baumannii(MDR-AB)was 32.23%,66.67%,25.51%and 20.00%,respectively.Conclusion The bacteria in sputum for patients with type 2 diabetes mellitus complicated with lower respiratory tract infection is mainly Gram-negative bacteria,and their resistance to antibiotics is high,and appropriate antibiotics should be selected in the course of treatment. 2018 Vol. 25 (25): 50-53 [Abstract] ( 156 ) HTML (38 KB)  PDF  (0 KB)  ( 24 ) 54 Clinical effect of modified standard trauma large craniotomy with bone flap operation treating severe craniocerebral trauma MA Yu-hong Objective To analyze the clinical effect of modified standard trauma large craniotomy with bone flap operation treating severe craniocerebral trauma.Methods Forty patients with severe craniocerebral trauma underwent surgical treatment in our hospital from March 2014 to April 2018 were selected as the study objects,and they were divided into the control group and observation group according to the computer random coding method,there were 20 cases in each group.The control group was treated with standard trauma large craniotomy with bone flap operation,while in the observation group were treated with modified standard trauma large craniotomy with bone flap operation.Intracranial pressure change,Glasgow coma scale (GCS)score,operative effect and the incidence of postoperative complications were compared between the two groups.Results The intracranial pressure of the observation group was(15.36±2.13)mmHg,which was lower than that of the control group([21.58±2.20]mmHg)5 days after operation,and the difference was statistically significant(P＜0.05).The GCS score of the observation group([10.15±2.32],[13.65±2.18]scores)3 months and 6 months after operation were higher than those of the control group([8.10±2.01],[10.12±2.15]scores),and the differences were statistically significant(P＜0.05).The total effective rate of the observation group (90.00%)was higher than that of the control group(60.00%),and the difference was statistically significant(P＜0.05).The total incidence of postoperative complications in the observation group(5.00%)was lower than that in the control group(30.00%),and the difference was statistically significant(P＜0.05).Conclusion The effect of modified standard trauma large craniotomy with bone flap operation treating severe craniocerebral trauma is more ideal. 2018 Vol. 25 (25): 54-56 [Abstract] ( 141 ) HTML (36 KB)  PDF  (0 KB)  ( 23 ) 57 Clinical effect of Ivabradine combined with continuous positive airway pressure ventilation in the treatment of obstructive sleep apnea-hypopnea syndrome complicated with arrhythmia YI Jing-de;CHEN Hao Objective To observe the clinical effect of Ivabradine combined with continuous positive airway pressure ventilation in the treatment of obstructive sleep apnea-hypopnea syndrome complicated with arrhythmia.Methods A total of 112 patients with obstructive sleep apnea-hypopnea syndrome with arrhythmia were treated in Huazhou People′s Hospital from March 2015 to April 2017 were selected.The patients treated with continuous positive airway pressure ventilation were selected as the control group,while the patients treated with Ivabradine combined with continuous positive airway pressure ventilation were selected as the observation group,and there were 56 patients in each group.The two groups were treated for 30 days.LAT,MAT,AHI,mSaO2,maximum heart rate,minimum heart rate,and arrhythmia rate were compared between the two groups.Results After treatment,the LAT,MAT,AHI,mSaO2,maximum heart rate,minimum heart rate,and arrhythmia rate in the two groups were improved compared with before treatment,and the differences were statistically significant(P＜0.05).After treatment,AHI of the observation group was significantly lower than that of the control group,mSaO2was significantly higher than that of control group,average arrhythmia rate was significantly lower than that of the control group,and the differences were statistically significant(P＜0.05).Conclusion The clinical effect of Ivabradine combined with continuous positive airway pressure ventilation in the treatment of obstructive sleep apnea-hypopnea syndrome with arrhythmia is more significant,and it can effectively improve the arrhythmia of the patients. 2018 Vol. 25 (25): 57-59转62 [Abstract] ( 139 ) HTML (41 KB)  PDF  (0 KB)  ( 22 ) 60 Risk factors analysis of colorectal adenoma occurrence in patients with type 2 diabetes mellitus LI Xiao-hui Objective To analyze the risk factors of colorectal adenoma occurrence in patients with type 2 diabetes mellitus.Methods A total of 2025 patients with type 2 diabetes mellitus complicated with colorectal adenoma diagnosed by our hospital from January 2011 to January 2017 were set as the observation group and 2700 patients with type 2 diabetes mellitus having no colorectal adenoma treated in our hospital at the same time were set as the control group.The general data between the two groups were compared and multivariate analysis was performed.Results There were no significant differences in gender,the rate of heredity,obesity,high fat diet rate and the incidence of polycystic ovary syndrome between the two groups(P>0.05).Multivariate analysis showed that metabolic syndrome,glycosylated hemoglobin and postprandial blood glucose were risk factors for colorectal adenoma in type 2 diabetic patients(P=0.000).Conclusion Metabolic syndrome,glycosylated hemoglobin and postprandial blood glucose were risk factors for type 2 diabetic patients complicated with colorectal adenoma. 2018 Vol. 25 (25): 60-62 [Abstract] ( 129 ) HTML (29 KB)  PDF  (0 KB)  ( 24 ) 63 Clinical research of accurate antiplatelet therapy after PCI under CYP2C19 gene polymorphism detection guidance in patients with acute coronary syndrome LIU Juan-feng;HE Wei-xi;LIU Zhi-hui;WANG Ping Objective To investigate clinical effect of accurate antiplatelet therapy after PCI under CYP2C19 gene polymorphism detection guidance in patients with acute coronary syndrome.Methods A total of 80 patients with acute coronary syndrome treated in our hospital from January 2016 to September 2017 were selected as the subjects,and divided into two groups by random number table method,with 40 cases in each group.The patients in control group received routine use of clopidogrel and aspirin,and patients in observation group used drug under CYP2C19 gene polymorphism detection guidance.The patients were followed up within 6 months,and the incidence of major adverse cardiac events and major bleeding events were compared between the two groups.Results The incidence of major adverse cardiac events in observation group was lower than that in the control group (P＜0.05).There was not significant difference in incidence of major bleeding events between the two groups.ConclusionAccurate antiplatelet therapy after PCI under CYP2C19 gene polymorphism detection guidance has significant effect on patients with acute coronary syndrome,which dosen′t increase the occurrence of bleeding events. 2018 Vol. 25 (25): 63-65 [Abstract] ( 156 ) HTML (33 KB)  PDF  (0 KB)  ( 142 ) 66 Efficacy of aerobic exercise on unstable angina LIN Yong-jian;HUANG Wei-peng Objective To investigate the clinical effect of aerobic exercise regimen for unstable angina.Methods A total of 100 patients with unstable angina treated in our hospital from January 2015 to January 2017 were selected as study subjects,and divided into observation group and control group according to the random number table method,with 50 cases in each group.In the control group,routine treatment alone was used.On the basis of routine treatment,aerobic exercise was added in the observation group.The serum C-reactive protein (CRP),blood lipids,homocysteine(Hcy)were compared between the two groups.Results There was no significant difference in the level of Hcy,CRP or blood lipid between the two groups before treatment(P＞0.05).After treatment,Hcy,CRP and blood lipid were all lower than those before treatment,with statistical significance(P＜0.05).The indexes in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).There was no significant difference in cardiac indexes such as left ventricular end-diastolic dimension (LVEDD),interventricular septum thickness(IVST),left ventricular ejection fraction(LVEF),posterior wall thickness(PWT)before treatment between the two groups(P＞0.05).After treatment,LVEDD,IVST and PWT in the two groups were lower than before treatment,while LVEF was higher than before treatment,with statistical significance (P＜0.05).The indexes of LVEDD,IVST and PWT in the observation group were lower than those in the control group,while the LVEF was higher than that in the control group,with statistical significance(P＜0.05).The total effectiveness rate in the observation group(94%)was significantly higher than that in the control group (76%),the difference was statistically significant(P＜0.05).Conclusion For patients with unstable angina in clinic,application of aerobic exercise can significantly improve the levels of Hcy and CRP,enhance cardiac function,and increase the total clinical effectiveness rate,which is of great significance to enhance patient′s quality of life. 2018 Vol. 25 (25): 66-68 [Abstract] ( 127 ) HTML (34 KB)  PDF  (0 KB)  ( 30 ) 69 Effect of nCAPA in the treatment of patients with OSAS combined with arrhythmia HU Kai;ZHUANG Man-ru;WU Ping-bin;XU Xian-bin;LIN Rui-bo Objective To observe the curative effect of nCAPA in the treatment of patients with OSAS combined with arrhythmia.Methods A total of 70 patients with OSAS combined with arrhythmia treated in our hospital from February 2015 to August 2017 were randomly divided into two groups,with 35 cases in each group.The control group was only treated with antiarrhythmic drugs by oral,and the observation group was treated with nCAPA on the basis of the antiarrhythmic drugs by oral,the treatment time of two groups was all 3 months.The total effective rates of two groups were compared.The related indicators such as the fastest HR at night,the slowest HR at night,SaO2low,TSTSaO2＜90%in both groups before and after treatment were detected by polysmith monitoring system.The occurrence of various types of arrhythmias during night sleep of two groups were detected by GWE-10 dynamic electrocardiograph.Results The total effective rate of the observation group(91.43%)was higher than that of the control group(71.43%),the difference was sitatistically significiant(P＜0.05).The slowest HR at night,SaO2low of the observation group after treatment were higher than those of before treatment and the control group after treatment(P＜0.05).The fastest HR at night,AHI,TSTSaO2＜90%and occurrence of various types of arrhythmias during night sleep were lower than those of before treatment and the control group after treatment(P＜0.05).Conclusion The nCAPA intervention is effective in the treatment of OSAS patients with arrhythmia.It can significantly reduce the arrhythmia and improve the symptoms of OSAS. 2018 Vol. 25 (25): 69-71 [Abstract] ( 135 ) HTML (35 KB)  PDF  (0 KB)  ( 26 ) 72 The correlation between lp-pla2 and left cardiac function in patients with coronary heart disease and the effect of erbesartan intervention HE Ding-yang;ZHAO Xin-sheng;HUANG Chuang-jie Objective To study the analysis of lipoprotein associated phospholipase A2(lipoprotein-associated phospholipase A2,Lp-PLA2)and the correlation of left heart function in patients with coronary heart disease (CHD),and explore he sand and the effect of intervention in patients with coronary heart disease(CHD).Methods A total of 116 cases of patients with coronary heart disease (CHD)and 50 cases of healthy volunteers with physical examination in the hospital from January 2016 to March 2018 were selected and set to coronary heart disease group and the control group respectively.The level of plasma Lp-PLA2 expression was measured and the level of plasma Lp-PLA2 expression was compared between the coronary heart disease group and the control group,and the left cardiac ejection fraction of the two groups was compared.According to the left cardiac ejection fraction,the patients in the coronary heart disease group were divided into left heart dysfunction group and normal left heart function group.The plasma Lp-PLA2 expression level of patients with different left heart function was compared,and the correlation between plasma Lp-PLA2 expression level and left heart function of patients with coronary heart disease was analyzed.Irbesartan drug intervention was applied to patients with coronary heart disease.The left ventricular ejection fraction and plasma Lp-PLA2 level were compared before and after treatment.Results The expression level of plasma Lp-PLA2 in the CHD group was higher than that in the control group (P＜0.05).The left cardiac ejection fraction in the CHD group was lower than the control group (P＜0.05).The expression level of plasma Lp-PLA2 in the left cardiac dysfunction group was higher than that in the left cardiac function group (P＜0.05),and the expression level of plasma Lp-PLA2 was negatively correlated with the left cardiac function(r=-0.783,P＜0.05).After treatment with irbesartan,the left cardiac ejection fraction of the patients with coronary heart disease was higher than that before treatment(P＜0.05),and the plasma Lp-PLA2 expression level was lower than that before treatment(P＜0.05).Conclusion The level of plasma Lp-PLA2 expression in patients with coronary heart disease is generally up-regulated,and the level of plasma Lp-PLA2 expression can reflect the left heart function of patients with coronary heart disease,and the intervention by irbesartan can effectively improve the left heart function of the patients,and reduce the level of Lp-PLA2 expression in plasma. 2018 Vol. 25 (25): 72-74 [Abstract] ( 150 ) HTML (34 KB)  PDF  (0 KB)  ( 28 ) 75 Clinical effect of clopidogrel in prevention of cardiovascular adverse events after coronary intervention WANG Dan Objective To explore the preventive effect of clopidogrel on adverse cardiovascular events(ACEs)after interventional treatment of coronary heart disease (CHD).Methods Eighty-four CHD patients admitted to our hospital from July 2015 to January 2017 were selected as the subjects,and divided into two groups according to the doubleblinding,with 42 cases in each group.In control group,patients were treated with low molecular weight heparin,while in observation group,clopidogrel was provided.The activated partial thromboplastin time,thrombin time,prothrombin and fibrinogen time,post-treatment thromboxane B2level,incidence of ACEs,and treatment satisfaction were compared between the two groups.Results There was no significant difference in activated partial thromboplastin time,thrombin time,prothrombin or fibrinogen time between the two groups(P＞0.05).After 6,12 and 24-hour treatment,the thromboxane B2levels in the observation group were(82.22±14.85)ng/L,(65.13±12.52)ng/L,and(46.70±9.12)ng/L respectively,all lower than those in the control group for(93.15±16.49)ng/L,(75.42±15.01)ng/L and(66.91±11.04)ng/L(P＜0.05).The incidence of ACEs in the observation group was 4.76%,which was lower than that in the control group accounting for 26.18%,with a significant difference (P＜0.05).The treatment satisfaction from patients in the observation group was 97.62%,higher than that in the control group accounting for 78.57%,with statistical significance(P＜0.05).Conclusion The use of clopidogrel in interventional treatment of CHD has a significant effect on the prevention of ACEs. 2018 Vol. 25 (25): 75-77 [Abstract] ( 158 ) HTML (36 KB)  PDF  (0 KB)  ( 27 ) 78 The application of family self-help heart rehabilitation model in patients with acute coronary artery syndrome GE Xiong;WANG Sai;CHEN Hui;LI Cheng-wu Objective To explore the efficacy of the family self-help heart rehabilitation model in patients with ACS,to understand the effects on living quality and exercise tolerance of patients.Methods A total of 88 patients treated in Xianning Center hospital,Xianning First People′s Hospital or Xianning Medical School affiliated Second Hospital diagnosed with ACS were selected as subjects from October 2016 to June 2017.They were divided into two groups by the random number table method,with 44 cases in each group.The control group received routine intervention under the guidance of non-cardiac rehabilitation specialists.The rehabilitation group received the targeted intervention under the guidance of cardiac rehabilitation doctors associate with multidisciplinary doctors from the top 3 hospitals.Following parameters including 6-minutes walk distance,cardiac rehabilitation,score of life quality were collected at baseline and after treatment of 3 months.Results After intervention,the chest tightness in the rehabilitation group was lower than that in the control group,and the ejection fraction in the rehabilitation group was higher than that in the control group(P＜0.01).PF,RP,BP,VT,SF,MH scores in the rehabilitation group were higher than those in the control group(P＜0.05).6-minutes walking distance in the rehabilitation group was longer than that in the control group (P＜0.05).Conclusion Effective family and cardiac rehabilitation guidance for ACS patients can effectively improve the patients′exercise tolerance,reduce the risk of disease recurrence,improve quality of life. 2018 Vol. 25 (25): 78-80转87 [Abstract] ( 165 ) HTML (37 KB)  PDF  (0 KB)  ( 21 ) 81 Influencing factors analysis of postoperative seizures in hypertensive intracerebral hemorrhage after Department of neurosurgery operation TANG Zhong;CHEN Qi-fu;LIAO Guang-sheng;CHEN Si;CHEN Jing-yu Objective To explore the influencing factors of postoperative seizures after Department of Neurosurgery operation for hypertensive intracerebral hemorrhage.Methods A total of 58 cases of patients with hypertensive intracerebral hemorrhage of diagnosis treated in Department of Neurosurgery,the Third People′s Hospital of Shenzhen City from May 2016 to October 2017 were retrospective analyzed.They were divided into two groups according to whether they were epileptic seizures after operation.Among them,17 patients with postoperative seizures were selected as the observation group,and 41 patients without seizures were used as control group.The levels of NSE and inflammatory factors in the two groups were observed,and their clinical characteristics were statistically analyzed.Results There were no significant difference in age and sex between the two groups(P＞0.05).The hematoma volume,hematoma location,postoperative rebleeding and operative mode between the two groups were significant differences(P＜0.05).After operation,the levels of TNF-α,IL-6,CPR and NES in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P＜0.05).The results of multiple factor Logistic regression analysis showed that the position of hematoma,hematoma volume,and postoperative rebleeding,including serum inflammatory factor TNF-α,IL-6,CPR,NSE were independent risk factors for epileptic seizures after high hemorrhage of cerebral hemorrhage(P＜0.05).Conclusion The location of hematoma,hematoma volume and operation mode are independent risk factors for early onset epilepsy after intracerebral hemorrhage,and should be paid close attention in clinical practice. 2018 Vol. 25 (25): 81-83转96 [Abstract] ( 146 ) HTML (37 KB)  PDF  (0 KB)  ( 19 ) 84 Observation effects of cognitive behavioral therapy for insomnia on generalized anxiety disorder with insomnia XIONG Yue;GONG Mei-yu;ZOU Sheng-jun;ZOU Xue-liang Objective To explore the effects of cognitive behavioral therapy for insomnia(CBT-I)on generalized anxiety disorder with insomnia.Methods Thirty six patients with generalized anxiety disorder and insomnia were recruited by advertisements posted at the hospital from September 2014 to September 2016.The patients were divided into therapy group and control group by random number table method,with 18 cases in each group.The patient received escitalopram treatment(P.O.,10 mg/d).The patients in the therapy group were treated by CBT-I,and the patients in the control group were educated with knowledge related to insomnia.The clinical effects were compared between the two groups.Results Sixteen patients in the therapy group and seventeen patients in the control group completed the study.After the CBT-I treatment,the Insomnia Severity Index scores and the Hamilton Anxiety Scale scores of the therapy group were both significantly lower than those of the control group,the differences were statistically significant(P＜0.05).The sleep efficiency and the percentage of deep sleep time of the therapy group were both significantly higher than those of the control group， the differences were statistically significant(P＜0.05).The HAMA scores of the therapy group was significantly lower than that of the control group,the differences were statistically significant (P＜0.05).Conclusion CBT-I can not only significantly improve the symptoms of insomnia,but also relieve the anxiety symptoms in patients with generalized anxiety disorders. 2018 Vol. 25 (25): 84-87 [Abstract] ( 137 ) HTML (39 KB)  PDF  (0 KB)  ( 26 ) 88 Effect of Atorvastatin on the postoperative residual hematoma in patients with chronic subdural hematoma LI Hua-qing;CHEN Zhi-sheng;LI Zhi-zhou Objective To observe the effect of atorvastatin on the postoperative residual hematoma in patients with chronic subdural hematoma.Methods A total of 56 patients who received burr hole irrigation and drainage (BHID)in the People′s Hospital of Xinxing County and the People′s Hospital of Yunfu City from March 2015 to November 2017 were selected as research subjects.The patients were randomly divided into two groups,with 28 cases in each group.The control group was treated with routine postoperative treatment.The observation group was treated with atorvastatin on the basis of the control group.After 12 weeks of regular follow-up,the postoperative residual hematoma,Markwalder grading and recurrence of the two groups were compared.Results The residual hematoma (6thweek,12thweek)of the observation group was less than that in the control group,Markwalder grading (12thweek)was superior to the control group,the differences were statistically significant(P＜0.05).Conclusion Atorvastatin can reduce the amount of residual hematoma after chronic subdural hematoma,improve brain function,worthy of clinical promotion. 2018 Vol. 25 (25): 88-90 [Abstract] ( 119 ) HTML (38 KB)  PDF  (0 KB)  ( 31 ) 91 Efficacy and safety of early continuous lumbar cistern drainage combined with magnesium sulfate for diffuse axonal injury YANG Zi-cai;ZHOU Zhong-yi;LI Ping-yu;YIN Zhi-jun;XU Yu-bin;LIN Jing-hua;HUANG Liu-lan Objective To summarize and analyze the clinical efficacy and treatment safety of early continuous lumbar cistern drainage in combination with magnesium sulfate for diffuse axonal injury (DAI).Methods Eighty DAI patients admitted to our hospital from August 2014 to August 2017 were selected as study objects.According to the random number table method,they were divided into observation group and control group,with 40 cases in each group.In the control group,early continuous lumbar cistern drainage alone was used,while in the observation group,early continuous lumbar cistern drainage plus magnesium sulfate was adopted.The clinical efficacy and safety of the two groups were compared.Results After treatment,the activity of daily living(ADL)score,Glasgow Coma Scale(GCS)score and Mini-Mental State Examination(MMSE)score in the observation group were all higher than those in the control group,with statistical significances (P＜0.05).In the observation group,the survival rate of vegetative was lower than that in the control group,with a significant difference (P＜0.05).There was no significant difference in incidence of complications between the two groups (P＞0.05).Conclusion The combination of early continuous lumbar cistern drainage and magnesium sulfate for DAI is beneficial to patient′s prognosis improvement as well as the life and mental state amelioration.At the same time,the drug safety is high,and it is worthy of promotion and application. 2018 Vol. 25 (25): 91-93 [Abstract] ( 121 ) HTML (36 KB)  PDF  (0 KB)  ( 13 ) 94 Clinical effect of combinatorial flexible ureteroscope combined with holmium laser in treatment of renal stones PENG Zhi;LI Feng-teng;LIN Bai Objective To investigate the effect of combinatorial flexible ureteroscope combined with holmium laser in treatment of renal stones.Methods A total of 150 patients with renal stones treated in our hospital from May 2018 to May 2017 were selected as study objects.The patients were divided into the combinatorial flexible ureteroscope combined with holmium laser group (75 cases)and the integrated flexible ureteroscope group (75 cases)according to the random number table method,and the two groups was treated by combinatorial flexible ureteroscope combined with holmium laser and integrated flexible ureteroscope.The stone size,operation time,postoperative hospital stay,stone clearance rate and the incidence complications were compared between the two groups.Results The operation time([88.11±35.11]min)and postoperative hospital stay([5.22±1.53]d)of the combinatorial flexible ureteroscope combined with holmium laser group were shorter than those of the integrated flexible ureteroscope group,and the differences were statistically significant(P＜0.05).The clearance rate of stones(93.33%)in the combinatorial flexible ureteroscope combined with holmium laser group was significantly higher than that in the integrated flexible ureteroscope group,and the incidence of complications(9.33%)was significantly lower than that in the integrated flexible ureteroscope group (P＜0.05).Conclusion The effect of combinatorial flexible ureteroscope combined with holmium laser in treatment of renal stones is significant. 2018 Vol. 25 (25): 94-96 [Abstract] ( 117 ) HTML (32 KB)  PDF  (0 KB)  ( 31 ) 97 Application study of selective perirenal drainage tube instead of nephrostomy tube after minimally invasive percutaneous nephrolithotomy XIONG Liu-shui;HUANG Ming Objective To explore the application effect of selective perirenal drainage tube instead of nephrostomy tube after minimally invasive percutaneous nephrolithotomy.Methods A total of 22 patients with percutaneous nephrolithotomy treated in Shicheng Traditional Chinese Medicine Hospital from January to December 2012 were selected as study objects,and they were divided into the control group and observation group according to drainage ways,and there were 11 cases in each group.The control group was treated with nephrostomy tube,while the observation group was treated with perirenal drainage tube.The incidence of complications,secondary bleeding volume,hospital stay and medical expenses were compared in patients between the two groups.Results The total incidence of complications in the observation group was 18.2%,which was significantly lower than that of the control group(45.5%),and the difference was statistically significant(P＜0.05).The secondary bleeding volume in the observation group was significantly fewer those that of the control group,the hospital stay was significantly shorter than the control group and the medical expenses were significantly lower than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion Compared with the nephrostomy tube,selective perinephric drainage tube has higher safety and better clinical effect,and it can reduce secondary blood flow,shorten the hospital stay and reduce medical expenses. 2018 Vol. 25 (25): 97-99 [Abstract] ( 108 ) HTML (36 KB)  PDF  (0 KB)  ( 26 ) 100 Effect analysis of percutaneous transforaminal endoscopic decompression for elderly lumbar lateral recess stenosis ZHANG Jie;YANG Jin-wei;JIAO Hong-xin;CHEN Zhi-hong;XU Hong-kou Objective To investigate the safety and efficacy of percutaneous transforaminal endoscopic decompression in the treatment of elderly lumbar lateral recess stenosis.Methods Twenty-three patients aged over 65 years with lumbar lateral recess stenosis admitted to our hospital from November 2015 to October 2017 were selected as study subjects.Percutaneous transforaminal endoscope was used for the “entrance” and “exit” of the lateral recess stenosis for decompression and nerve roots loosening.The visual analogue scale (VAS)scores and Oswestry disability index(ODI)in the last follow-up before and after the operation were compared.The modified MacNab was used to evaluate the efficacy.Results The VAS score in last follow-up after the operation was(1.48±0.95)points,lower than that before the operation,(8.17±0.94)points,which was displayed significant difference (P＜0.01）.The ODI in the last follow-up after the operation was (22.01±7.86),which was lower than that before the operation,(68.96±7.97)with significant difference(P＜0.01）.The postoperative effect was evaluated using the modified MacNab,Including 12 excellent cases,9 good cases,2 fair cases,and 0 poor case.The excellent and good rate was 91.3%.Conclusion Percutaneous transforaminal endoscopic decompression in the treatment of elderly lumbar lateral recess stenosis is safe,effective,minimal invasion,and few complications,which is easily accepted by the majority of elderly patients. 2018 Vol. 25 (25): 100-102 [Abstract] ( 140 ) HTML (36 KB)  PDF  (0 KB)  ( 26 ) 103 Clinical effect of proximal femoral nail anti-rotation in the treatment of osteoporotic intertrochanteric fractures in elderly patients CHEN Run-bin;CHEN Xing-kai;WU Ting-huan Objective To study the feasibility and safety of proximal femoral nail anti-rotation(PFNA)in the treatment of osteoporotic intertrochanteric fractures in the elderly patients.Methods 167 elderly patients with osteoporotic intertrochanteric fractures who were admitted to our hospital from January 2015 to January 2017 was retrospectively analyzed.The patients were divided into experimental group and control group according to different surgical methods.89 patients in the experimental group were given PFNA internal fixation.78 patients in the control group were given joint replacement.The operation time,intraoperative and postoperative blood loss,length of hospital stay,postoperative Harris score,and postoperative complication indence were compared between the two groups.Results In the experimental group,the operation time was shorter than those in the control group and intraoperative blood was losser than those in the control group.However,the length of hospital stay and weight-bearing time were longer than those in the control group,and the differences were statistically significant(P＜0.05）;Harris scores in the experimental group were higher than those in the control group.The rate of postoperative joint dislocation,deep vein thrombosis,and pulmonary infection rate were lower in the experimental group than those in the control group.The differences were statistically significant(P＜0.05）.Conclusion PFNA not only has a good curative effect but also has fewer complications in the treatment of elderly osteoporotic intertrochanteric fractures.It is worthy of clinical promotion. 2018 Vol. 25 (25): 103-105 [Abstract] ( 127 ) HTML (34 KB)  PDF  (0 KB)  ( 25 ) 106 The effect of negative pressure closed drainage technique in treating patients with orthopaedic trauma YUAN Guo-hui Objective To explore the effect of negative pressure closed drainage technique(VSD)on orthopedic trauma patients.Methods 60 cases of orthopaedic trauma patients admitted in our hospital from January 2015 to December 2017 were selected according to the randomized double blind method,they were divided into the treatment group(32 cases)and control group (28 cases),treatment group was given treatment of VSD,the control group was given conventional treatment therapy.The clinical efficacy of the two groups was compared.Results The total effective rate of the treatment group(96.87%)was significantly higher than that of the control group(71.43%),and the difference was statistically significant(P＜0.05）.Before the treatment,VAS score of two groups was no significant difference (P＞0.05）,after treatment,VAS score two groups of was significantly lower than before treatment,and the treatment group was significantly lower than control group (P＜0.05）;Dressing changing in times treatment group was less than the control group,implementingⅡperiod during the surgery operation time and hospital stay in the treatment group were shorter than the control group,the difference was statistically significant(P＜0.05）;the time of wound healing,wound healing time and total healing time of wound healing in the treatment group were significantly shorter than that in the control group (P＜0.05）.Conclusion The implementation of the VSD technique is a more significant effect of conventional treatment,patients with less postoperative pain,less dressing,Ⅱperiod shorter operation time and hospital stay,wound healing faster,worthy of clinical popularization and application. 2018 Vol. 25 (25): 106-108 [Abstract] ( 131 ) HTML (55 KB)  PDF  (0 KB)  ( 23 ) 109 Effect of uterine arterial embolization in patients with placenta accreta WANG Xiao-qin;FU Xiu-hua Objective To investigate the clinical value of uterine arterial embolization(UAE)in placental implantation.Methods From January 2015 to December 2017,84 patients with placenta accreta in our hospital were selected as research subjects.They were equally divided into two groups in random，42 cases in each group.In control group,conventional therapy was used,while in observation group,UAE was adopted.Both groups were treated with complete curettage of uterine cavity.The placenta thoroughly cleared time,blood stanching time,intraoperative blood loss,uterine retention,placental discharge probability,human chorionic gonadotropin(HCG)recovery time,and incidence of adverse events were observed in the two grops.Results In the observation group,the time of total placental clearance and blood stanching were(6.98±0.43)d and(17.33±2.92)d,both shorter than in the control group([10.45±1.98],[25.49±5.06]days).The blood loss in the observation group was(823.49±7.71)ml,lesser than that in the control group.The uterine retention rate and placental discharge rate were 100.00%and 92.86%in the observation group,higher than those in the control group,accounting for 80.90%and 73.81%,which were displayed statistical significance (P＜0.05）.The recovery time of HCG in the observation group was(6.77±1.43)d,shorter than that of the control group.The incidence of adverse events was 2.38%,lower than that of the control group accounting for 14.29%with a significant difference(P＜0.05）.Conclusion UAE is of high value in the treatment of placenta accrete,which can effectively excrete the placenta and protect the uterus.The prognosis is favorable and the safety is high. 2018 Vol. 25 (25): 109-111 [Abstract] ( 101 ) HTML (31 KB)  PDF  (0 KB)  ( 28 ) 112 Influence of Doula delivery on the duration of labor and pregnancy outcome of parturients LIU Zhong-hua Objective To analyze the effect of Doula delivery on the duration of labor and pregnancy outcome of parturients during childbirth.Methods With the consent of the parturients and their families,altogether 158 cases of parturients admitted to the Department of Obstetrics and Gynecology in our hospital from January to December 2017 were selected as the object of this research and rondomly divided into two groups,79 cases in each group.The control group was received routine childbirth nursing,while the study group was supplemented by Doula delivery.The duration of labor,spontaneous delivery rate and other delivery indicators were compared between the two groups.Results Each and total duration of labor of the study group were significantly shorter than those of control group,with statistically significant difference (P＜0.05）.The pregnancy outcome of the study group was significantly better than that of control group.The natural delivery rate of the study group was significantly higher than that of the control group.The newborn Apgar score of the study group was significantly higher than that of the control group.The amount of hemorrhage during the duration of labor was lesser than that of control group,with statistically significant difference between the two groups(P＜0.05）.ConclusionApplication of Doula-guided labor for assisted delivery can effectively shorten the duration of labor,improve the natural delivery rate and the Apgar score of the newborn,and reduce the bleeding.It can guarantee the safety of mother and baby better,and has a high value of popularization and application. 2018 Vol. 25 (25): 112-114 [Abstract] ( 102 ) HTML (35 KB)  PDF  (0 KB)  ( 23 ) 115 Clinical effect of S-adenosylmethionine combined with ursodeoxycholic acid in the treatment of intrahepatic cholestasis during pregnancy LI Na Objective To investigate the clinical efficacy of S-adenosylmethionine （SAM）combined with ursodeoxycholic acid in the treatment of intrahepatic cholestasis during pregnancy （ICP）.Methods A total of 64 patients with ICP from May 2015 to May 2017 in our hospital were selected as study subjects.Random number table method was used to divide them into control group and study group,32 cases in each group.Both groups were given routine symptomatic treatment.In the control group,ursodeoxycholic acid was added,while in the study group,SAM combined with ursodeoxycholic acid was added.The clinical efficacy and maternal and infant outcomes were compared between the two groups.Results The scores of pruritus symptoms and related indexes of liver function after treatment in both groups were significantly lower than those before treatment(P＜0.05）.The scores of pruritus symptoms and related indexes of liver function after treatment in the study group were significantly lower compared with those in the control group with statistical significance (P＜0.05）.In the study group,the incidence of cesarean section,neonatal asphyxia,postpartum hemorrhage,fetal distress and preterm birth were significantly lower than those in the control group with statistical significance (P＜0.05）.Conclusion The combination of SAM and ursodeoxycholic acid in the treatment of ICP can obtain a definite effect.It can significantly improve the symptoms of pruritus,liver function indicators and maternal and fetal outcomes. 2018 Vol. 25 (25): 115-117 [Abstract] ( 118 ) HTML (32 KB)  PDF  (0 KB)  ( 27 ) 118 Clinical effect of laparoscopy combined with Triptorelin Acetate in the treatment of endometriosis YANG Xiao-mei;WEI Feng-ying;YANG Wei-lin;CHEN Shao-fen Objective To explore the clinical effect of laparoscopy combined with Triptorelin Acetate in the treatment of endometriosis(EMT).Methods A total of 90 patients with EMT treated in our hospital from October 2015 to December 2017 were selected as study subjects and randomly divided into two groups,45 cases in each group.In the observation group,laparoscopic surgery combined with Triptorelin Acetate was adopted,while in the control group,laparoscopic surgery with Gestrinone was used.The clinical indicators,incidence of adverse reactions,and recurrence rate were compared in the two groups.Results The recovery time of ovulation and menstruation in the observation group were(15.22±1.02)d and(26.52±1.02)d,significantly shorter than those of the control group,(23.59±1.65)d and(39.38±1.65)d respectively (P＜0.05）.The total incidence of adverse reactions in the observation group was lower than that in the control group (P＜0.05）.The recurrence rate of patients with EMT in the observation group was lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Laparoscopy combined with Triptorelin Acetate obtains a significant effect on the treatment of EMT,and can effectively improve the patient′s various indicators in high safety simultaneously,which is worthy of study. 2018 Vol. 25 (25): 118-120 [Abstract] ( 144 ) HTML (31 KB)  PDF  (0 KB)  ( 38 ) 121 Clinical application of fetal fibronectin in predicting premature delivery LI Jian Objective To observe the value of fetal fibronectin(fFN)detection in predicting premature delivery.Methods All the subjects were selected from pregnant women admitted to the Department of Obstetrics and Gynecology clinic from January 2016 to January 2018 in our hospital and 218 were randomly selected.Enzyme-linked immunosorbent assay was used to detect fFN levels in all pregnant women.According to fFN levels,they were divided into two groups.FFN levels≥50 as/ml were positive for fFN levels,and fFN levels＜50 as/ml were negative for fFN levels.A total of 48 pregnant women in the positive group and 170 pregnant women in the negative group were included.The incidence of preterm birth was compared between the two groups of fetuses,and the clinical predictive value of fFN levels for fetal preterm birth was analyzed.Results The results showed that the fertility rates of pregnant women with positive fFN levels group within 7 days,14 days,34 weeks,and 37 weeks were 8.33%,12.50%,16.67%,and 25.00%,respectively,which were significantly higher than those of fFN levels.There was a significant difference in the data between the groups(0.00%,1.18%,4.71%,and 11.76%)(P＜0.05）.The sensitivity of the fFN index was 50.00%(30/60),the specificity was 88.61% (140/158),the accuracy was 77.98% (170/218),and the positive predictive value was 62.50%（30/48）.Conclusion In the prediction of premature birth,fFN detection has higher sensitivity and positive predictive value.It has higher use value in clinical practice and has the value of recommended application. 2018 Vol. 25 (25): 121-123 [Abstract] ( 130 ) HTML (31 KB)  PDF  (0 KB)  ( 18 ) 124 The application value of 64 slice spiral CT angiography in the diagnosis of intracranial aneurysms LU Xiao-wen Objective To investigate the application value of 64 slice spiral CT angiography(CTA)in the diagnosis of intracranial aneurysms.Methods Altogether 40 cases of patients diagnosed with intracranial aneurysms by digital subtraction angiography(DSA)in our hospital from January to August,2017 were selected as research objects.The imaging data of patients examined by CTA and DSA were compared and analyzed.The advantages of CTA were evaluated,including the appearance of the aneurysm morphology and location,and the relationship between the wall thrombus,aneurysm,calcification and the surrounding structure.Results The comparsion of accuracy of CTA and DSA in the diagnosis of intracranial artery position,shape and the diameter of intracranial aneurysm were not statistically significant(P＞0.05).Compared with DSA,CTA could clearly show the calcification and thrombus of intracranial aneurysm,and the relationship between intracranial aneurysm and surrounding structure was better,with statistically significant difference(P＜0.05).Conclusion The diagnosis of intracranial aneurysms by CTA can clearly show the shape,location,calcification,wall thrombus and the relationship with the surrounding structure,which can be used as an imaging method for diagnosis and preoperative evaluation of intracranial aneurysms. 2018 Vol. 25 (25): 124-126 [Abstract] ( 125 ) HTML (33 KB)  PDF  (0 KB)  ( 32 ) 127 Diagnostic value of 64-slice spiral computed tomography coronary angiography in coronary heart disease patients with atypical chest pain CHEN Rong-pan;LIANG Guo-jian;GUAN Jian-wei Objective To observe and analyze the diagnostic value of 64-slice spiral computed tomography(CT)coronary angiography in coronary heart disease patients with atypical chest pain.Methods Eighty patients with atypical chest pain who were treated in our hospital from October 2015 to October 2017 were enrolled in this study.Coronary artery imaging with 64-slice spiral CT was used for the diagnosis,and the accuracy,specificity and sensitivity of the diagnosis method were evaluated based on the results of selective coronary angiography.Results The accuracy,sensitivity and specificity of 64-slice spiral CT coronary angiography were 87.50%,87.50%,and 87.50%,respectively.The comparsion of accuracy,specificity and sensitivity between 64-slice spiral CT coronary angiography and selective coronary angiography showed statistically significant difference (χ2=10.6667,P=0.0011; χ2=2.1333,P=0.1441; χ2=8.5333,P=0.0035).The diagnosis rates of mild,moderate,and upper stenosis using 64-slice spiral CT coronary angiography were 75.56%,93.98%,and the difference between the two data was significant(χ2=9.0523,P=0.0026).The comparsion of sensitivity with 64-slice spiral CT coronary angiography used to detect three coronary vascular lesions in the right coronary artery,left circumflex artery,and left anterior descending coronary artery showed statistically significant difference (χ2=28.3080,P=0.0001),while there was no statistically significant difference in specificity and accuracy (χ2=0.0756,P=0.9629;χ2=2.8489,P=0.2406).Conclusion In the diagnosis of atypical chest pain patients with coronary heart disease,the effect of 64-slice spiral CT coronary angiography is acceptable,but because of its non-invasive advantages,it can be used as a basic diagnostic identification method. 2018 Vol. 25 (25): 127-129转136 [Abstract] ( 113 ) HTML (38 KB)  PDF  (0 KB)  ( 23 ) 130 Effect analysis of Allopurinol in the treatment of acute cerebral ischemic stroke complicated with carotid artery plaque JIANG Jun-hua Objective To investigate the effect of Allopurinol in the treatment of acute cerebral ischemic stroke complicated with carotid artery plaque.Methods One hundred and twenty patients with acute cerebral ischemic stroke complicated with carotid plaque were enrolled from January to September in 2017.They were randomly divided into the control group and the observation group,with 60 cases in each group.In the control group,Atorvastatin in combination with Aspirin Enteric-coated Tablets was used,while in the observation group,Allopurinol was added on the basis of the control group.The change of carotid plaque before and after treatment and therapeutic effect were compared between two groups.Results There was no significant difference in the property of plaque before treatment between two groups (P＞0.05).The incidence of stable plaques after treatment in two groups was higher than that before treatment,and the difference was statistically significant(P＜0.05).The incidence of stable plaques in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the plaque area before treatment between the control group ([0.24±0.12]cm2)and the observation group([0.23±0.11]cm2)(P＞0.05).The plaque area in the observation group([0.17±0.07]cm2)after treatment was significantly smaller than that in the control group ([0.21±0.09]cm2),and the difference was statistically significant(P＜0.05).The total effective rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the level of uric acid before treatment between the observation group ([528±58]μmol/L)and the control group([530±60]μmol/L)(P＞0.05).The level of uric acid after treatment in the observation group was(416±94)μmol/L,which was significantly lower than that before treatment and was lower than that in the control group of(525±57)μmol/L,with statistically significant difference(P＜0.05).During the treatment,2 cases(3.3%)in the observation group had an increase in the level of glutamate aminotransferase 2 times more than the normal upper limit.No adverse reactions occurred in the control group.There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion Allopurinol has a significant effect in the treatment of acute cerebral ischemic stroke complicated with carotid artery plaque.It can effectively stabilize carotid plaque and reduce plaque area,which is worthy of promotion. 2018 Vol. 25 (25): 130-132转140 [Abstract] ( 164 ) HTML (38 KB)  PDF  (0 KB)  ( 29 ) 133 Effect of Metformin and Ethynylestradiol Cyproteronee in the treatment of polycystic ovary syndrome infertility XIAO Jing;HUANG Jia;GUO Chen;JIANG Ru Objective To investigate the effect of Metformin and Ethynylestradiol Cyproterone in the treatment of polycystic ovary syndrome infertility.Methods A total of 60 cases of infertility patients with polycystic ovary syndrome from March 2015 to February 2016 treated in our hospital were selected as study subjects.They were divided into the control group and the study group according to the parity method,with 30 cases in each group.The control group was treated with Ethynylestradiol Cyproterone alone,and the study group was given Metformin on the basis of Ethynylestradiol Cyproterone.All patients were treated for 3 months.Sex hormone levels (follicle stimulating hormone[FSH],luteinizing hormone[LH],pituitary prolactin[PRL],testosterone[T],estradiol[E2],progesterone[P]),metabolic levels(Insulin receptor[IR],fasting insulin[FINS],fasting glucose[FBS]),postoperative ovulation status and adverse reactions were compared in two groups.Results The levels of LH([8.31±2.15]IU/L),T([1.32±0.38]nmol/L),E2([114.66±8.80]pmol/L),IR(1.66±0.54)and FINS([7.44±2.31]mIU/ml)in the study group were lower than those in the control group([11.34±2.39]IU/L,[1.94±0.48]nmol/L,[118.57±7.90]pmol/L,[2.60±0.57],[12.00±2.69]mIU/ml),and abortion rate(3.33%)in the study group were lower than that in the control group (20.00%),the ovulation rate (73.33%)and pregnancy rate(43.33%)in the study group were higher than those in the control group(53.33%,23.33%),and the differences were statistically significant(P＜0.05).There was no significant difference in the incidence of adverse reactions between two groups(P＞0.05).ConclusionThe effect of Metformin and Ethynylestradiol Cyproterone in the treatment of infertility patients with polycystic ovary syndrome is significant. 2018 Vol. 25 (25): 133-136 [Abstract] ( 149 ) HTML (38 KB)  PDF  (0 KB)  ( 31 ) 137 Effect observation of Pramipexole combined with Levodopa and Benserazide Hydrochloride Tablets in the treatment of advanced Parkinson′s disease XING Xiao-lian LI Wei-rong Objective To investigate the clinical effect of Pramipexole combined with Levodopa and Benserazide Hydrochloride Tablets in the treatment of advanced Parkinson′s disease.Methods A total of 80 patients with advanced Parkinson′s disease who were admitted to our hospital from June 2016 to June 2017 were selected as the study subjects.According to the random number table method,they were divided into observation group (40 cases)and control group (40 cases).The control group was treated with Levodopa and Benserazide Hydrochloride Tablets alone,and the observation group was given Pramipexole combined with Levodopa and Benserazide Hydrochloride Tablets.The control rate of advanced Parkinson′s disease,the simple intelligent mental state examination scale scores,the Hamilton depression scale scores,and the Parkinson′s comprehensive scale scores before and after the intervention,expression ability scores,the memory scores,the reading and understanding scores,time concept scores after treatment and incidence of adverse drug reactions were compared between two groups.Results The control rate of Parkinson′s disease in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).There were no significant differences in the simple intelligent mental state examination scale scores,the Hamilton depression scale scores,and the Parkinson′s comprehensive scale scores before intervention between two groups(P＞0.05).The scores of the simple intelligent mental state examination scale after the intervention in two groups were higher than those before the intervention,the scores of the Hamilton depression scale and the Parkinson′s comprehensive scale were lower than those before the intervention,and the differences were statistically significant(P＜0.05).The scores of the simple intelligent mental state examination scale after the intervention in the observation group were higher than those in the control group,the scores of the Hamilton depression scale and the Parkinson′s comprehensive scale were lower than those in the control group,and the differences were statistically significant(P＜0.05).The scores of expression ability,memory,reading and understanding,and time concept of the observation group were higher than those of the control group,and the differences were statistically significant(P＜0.05).There was no significant difference in the incidence of adverse reactions between two groups(P＞0.05).Conclusion Pramipexole combined with Levodopa and Benserazide Hydrochloride Tablets has a definite effect in the treatment of advanced Parkinson′s disease.It can effectively improve the clinical symptoms,improve the patients′cognitive function,depressive mood and mental state,and has no serious adverse reactions,which is safe and effective and worthy of promotion and application. 2018 Vol. 25 (25): 137-140 [Abstract] ( 118 ) HTML (39 KB)  PDF  (0 KB)  ( 28 ) 141 Effect of Mifepristone combined with Methotrexate in the treatment of ectopic pregnancy LU Hong;DONG Lin Objective To explore the effect of Mifepristone combined with Methotrexate in the treatment of ectopic pregnancy.Methods Altogether 70 cases of patients with ectopic pregnancy treated in our hospital from January 2013 to August 2017 were randomly selected as the study objects.They were divided into control group and observation group by simple random method,with 35 cases in each group.The control group was treated with Methotrexate,and the observation group was treated with Mifepristone combined with Methotrexate.The total effective rate,the negative time of blood β-human chorionic gonadotropin(β-HCG),the disappearance time of the gestational sac and the incidence of adverse reactions were compared between two groups.Results The total effective rate of the observation group(97.14%)was higher than that of the control group(80.0%),and the difference was statistically significant(P＜0.05).The negative time of blood β-HCG and the disappearance time of the gestational sac in the observation group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The incidence of adverse reactions in the observation group was 11.43%,compared with 20%in the control group,and the difference was not statistically significant(P＞0.05).ConclusionMifepristone combined with Methotrexate is effective in the treatment of ectopic pregnancy,the safety of drug use is high,and it can effectively improve the clinical symptoms of patients and promote the recovery of patients as soon as possible,which is beneficial to the formation of a good doctor-patient relationship. 2018 Vol. 25 (25): 141-143 [Abstract] ( 106 ) HTML (34 KB)  PDF  (0 KB)  ( 27 ) 144 Effect and safety of different doses of Mifepristone in the treatment of uterine fibroids HUANG Yun-fu;SHI Ling-ting;LI Qiao-hua;LIAO Hong-yuan Objective To investigate the effect and safety of Mifepristone at different doses in the treatment of uterine fibroids.Methods A total of 100 patients with uterine fibroids treated in Family Planning Service Center of Xingning Maternal and Child Health Care Hospital of Guangdong Province from January 2016 to December 2017 were enrolled in the study and divided into control group and study group according to the random number table method,with 50 cases in each group.In the control group,25.00 mg/d Mifepristone was used,while in the study group,12.50 mg/d Mifepristone was adopted.The volume of uterine fibroids,serum hormone levels,clinical control rate,and incidence of adverse reactions before and after treatment were compared between two groups.Results Before treatment,there were no significant differences between uterine fibroid volume([45.30±12.55]cm3),follicle-stimulating hormone(FSH)([81.80±7.25]ug/L),luteinizing hormone(LH)([9.35±1.40]U/L),estradiol(E2)([276.65±21.65]pmol/L),progesterone(P)([7.80±1.45]nmol/L)in the study group and those respectively in the control group([45.35±12.50]cm3,[81.85±7.20]μg/L,[9.30±1.45]U/L,[276.60±21.60]pmol/L,[7.85±1.40]nmol/L)(P＞0.05).After treatment,the uterine fibroid volume,FSH,LH,E2,and P in the study group were respectively(30.15±9.88)cm3,(6.33±1.29)μg/L,(8.08±1.21)U/L,(176.50±20.08)pmol/L,and(4.15±0.99)nmol/L,and in the control group they were respectively(30.03±9.25)cm3,(6.35±1.35)μg/L,(8.05±1.15)U/L,(175.90±21.55)pmol/L,and(4.10±0.95)nmol/L,which did not display statistical significance(P＞0.05).The clinical control rate in the study group was 96.00%,which was higher than that in the control group accounting for 80.00%,and the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the study group(10.00%)was lower than that in the control group(38.00%),and the difference was statistically significant(P＜0.05).Conclusion The use of 12.50 mg/d Mifepristone for uterine fibroids is effective and safe,which is worthy of promotion and application. 2018 Vol. 25 (25): 144-146转150 [Abstract] ( 142 ) HTML (38 KB)  PDF  (0 KB)  ( 20 ) 147 Clinical effiect of Imipenem in the treatment of stroke-associated pneumonia WU Shan-yan;WANG Qiang;XIANG Zhi-qiang;CHEN Xiao-fang Objective To analyze the clinical effect of Imipenem in the treatment of stroke-associated pneumonia.Methods A total of 90 patients with stroke-associated pneumonia admitted to the intensive care unit of department of respiratory medicine in our hospital from August 2015 to August 2017 were selected as study subjects.They were divided into the antibiotic group and the imipenem group according to the parity group method,with 45 cases in each group.Patients in the antibiotic group were treated with the corresponding antibiotics alone,and patients in the imipenem group were treated with Imipenem on the basis of antibiotic therapy.The time of normal temperature,antibiotic use,hospital stay,and the rate of bacterial clearance were compared between two groups.The results of laboratory test(white blood cell count[WBC],neutrophil count,C-reactive protein[CRP],procalcitonin[PCT])and scores of national institute of health stroke scale (NIHSS)before and after treatment were compared between two groups.Results After treatment,the body temperature returned to normal time in the imipenem group was(3.10±0.56)d,the antibiotic use time was(5.15±1.64)d,and the time of hospital stay was(11.30±3.21)d,which were significantly shorter than those in the antibiotic group([3.89±1.12]d,[7.12±1.35]d,[13.47±2.18]d),and the differences were statistically significant(P＜0.05).The rate of bacterial clearance in the imipenem group was 93.33%,which was higher than that in the antibiotic group(75.56%),and the difference was statistically significant(P＜0.05).The level of WBC in the imipenem group was(6.74±1.52)×103/L,the neutrophil count was(0.56±0.15),the level of CPR was(14.55±3.08)mg/L,and the level of PCT was(3.26±0.35)ng/ml,which were lower than those in the antibiotic group([10.47±4.26]×103/L,[1.01±0.12],[20.46±3.57]mg/L,[4.65±1.20]ng/ml),with statistically significant difference(P＜0.05).There was no significant difference in the score of NIHSS before treatment between two groups(P＞0.05).The NIHSS scores after treatment in two groups were significantly lower than those before treatment,and the differences were statistically significant(P＜0.05).The NIHSS scores after treatment in the imipenem group were(10.22±1.34)points,which were significantly lower than those in the antibiotic group([12.31±1.50]points),and the differences were statistically significant(P＜0.05).Conclusion The clinical effect of Imipenem in the treatment of stroke-associated pneumonia is definite.It can shorten the course of disease and time of hospitastay,effectively eliminate bacteria,which is worthy of clinical promotion and application. 2018 Vol. 25 (25): 147-150 [Abstract] ( 114 ) HTML (38 KB)  PDF  (0 KB)  ( 27 ) 151 Experience of Professor Zhao Shu-hua in the treatment of diseases relevant to damp-heat in lower jiao LIU Ming-hui;ZHAO Shu-hua;XUE Jun-lai As a common pattern in traditional Chinese medicine(TCM),damp-heat in lower jiao can be found in various sites with multiple clinical manifestations and complex changes.The main etiology and pathogenesis are dysfunction of the spleen and kidney leading to failure of water metabolism and distribution which causes dampness accumulation converting into heat in stagnation.Although it is not difficult to identify the pattern,the treatment principles are various and the good and bad are intermingled which lead to poor effect.Professor Zhao Shuhua is a distinguished TCM doctor in Jilin Province,who has been engaged in the clinical teaching of Chinese medicine for over 40 years.The professor expertes in TCM Chinese classics and is familiar with the theory of different schools.The research tidies up the professor′s empirical cases and retrieves the relevant literature,and tries to clarify the professor′s acknowledgement of damp-heat in lower jiao pattern,treatment principle,and corresponding formulas by summarizing 6 common diseases such as renal stone,chronic prostatitis,and pelvic inflammatory disease.This serves as a modest spur for our fellow TCM practitioners to further explore the pattern. 2018 Vol. 25 (25): 151-153 [Abstract] ( 119 ) HTML (35 KB)  PDF  (0 KB)  ( 21 ) 154 Analysis on the treatment of geriatric depression from the theory of yang PENG Jian;OUYANG Wei The incidence rate of geriatric depression is high,and it is imperative to strengthen its research,prevention and treatment.In the author′s clinical practice,it has been found that geriatric depression is mainly characterized by depressed mood,slow thinking,and decreased initiative,and the symptom of a lack of yang(yang deficiency)is shown.The dialectical syndrome belongs to the negative and soft syndromes.After analysis,it is believed that the lack of yang is an important factor in the onset of geriatric depression.Combined with clinical symptoms,application of Sini Powder,and adverse reactions of anti-depression Western medicine,the concept of warming kidney-yang and heart-yang in the treatment of geriatric depression has been put forward.Also,the combined internal and external treatment is applied in clinical treatment verification,trying to provide new ideas and methods for the treatment of geriatric depression. 2018 Vol. 25 (25): 154-156 [Abstract] ( 124 ) HTML (37 KB)  PDF  (0 KB)  ( 22 ) 157 Investigation of the traditional Chinese medicine constitution in patients with peptic ulcer and its relationship with Helicobacter pylori infection ZHOU Wen-bo;LI Ming;RAO Juan Objective To investigate the traditional Chinese medicine (TCM)constitution of patients with peptic ulcer and its relationship with Helicobacter pylori(Hp)infection.Methods A total of 169 patients with peptic ulcer treated in our hospital from February 2015 to November 2017 were selected,and the type of the physique of TCM was judged by nine basic constitution classification sub-scales in Classification and determination of TCM constitution,and Hp infection in patients with different TCM constitution was observed.Results In 169 patients with peptic ulcer,the TCM constitution was calm physique,yang-deficiency physique,phlegm-dampness physique,blood stasis physique,specialty physique,qi-deficiency physique,yin-deficiency physique,dampness-heat physique and qi-depression physique,of which yang-deficiency physique was the most,and it accounted for 21.30% (36/169),followed by damp and heat physique,accounting for 15.38%(26/169),while specialty physique was the least,accounting for 0.59%(1/169).There was no significant difference in the positive and negative rate of Hp in peptic ulcer patients with TCM constitution of calm physique,phlegm-dampness physique,blood stasis physique,specialty physique,yin-deficiency physique and qidepression physique (P＞0.05),the positive rate of Hp in patients with peptic ulcer with yang-deficiency physique,qideficiency physique and damp-heat physique constitution were higher than those in negative rate,and the differences were statistically significant(P＜0.05).Conclusion Peptic ulcer patients with yang-deficiency physique are susceptible to Hp infection,and it is of great significance to clarify the type of TCM constitution of patients,and adjust the constitution help to prevent Hp infection and recurrence of peptic ulcer. 2018 Vol. 25 (25): 157-159转163 [Abstract] ( 120 ) HTML (37 KB)  PDF  (0 KB)  ( 32 ) 160 Professional attitude and influencing factors of sharp injury occurrence among nursing interns ZHANG Hong;GAO Huan-ling;LI Hong-mei;XUE Jing-jing Objective To understand the professional attitude of nursing interns and the related factors of sharp injury,and to provide basis for formulating effective prevention and intervention measures.Methods Convenient sampling method was used,and the demographic data and sharp injuries were made into questionnaires.A total of 217 nursing interns accepted by Fenyang College of Shanxi Medical University from June 2017 to June 2018 were investigated retrospectively with Nurse professional attitude scale.Results The average score of nursing interns′professional attitude was(2.17±0.76)points.Univariate analysis reaults showed that there were no significant difference in the incidences of sharp injury among nursing interns of different sex,age (≥20 years old,＜ 20 years old)and places of origin(cities,towns and rural areas)(P＞0.05).The incidence of sharp injury among specialty nursing interns was higher than that of undergraduate nursing students(P＜0.05);the incidence of sharp injury among family volunteer and dispensing nursing interns were higher than those of voluntary applicants(P＜0.05);the incidence of sharp injury among extroverted nursing interns was higher than that of introverted nursing interns (P＜0.05).The incidence of sharp injury in nursing interns with occupational attitude score＜4.5 points was higher than that with occupational attitude score≥4.5 points(P＜0.05).Multivariate analysis results showed that education level,volunteer status,nursing students′personality and professional attitude were the significant influencing factors(P＜0.05).Conclusion Nursing interns have lower occupational attitude,higher risk of occupational exposure and higher incidence of sharp injury,and it is necessary to strengthen training on sharp injury prevention,strengthen psychological intervention and rebuild professional confidence. 2018 Vol. 25 (25): 160-163 [Abstract] ( 116 ) HTML (37 KB)  PDF  (0 KB)  ( 34 ) 164 Application of the introspection diary method in nursing soft skill training of student nurse LIU Yin;HE Yan-ping Objective To explore the application effect of the introspection diary method in nursing soft skill training of student nurse.Methods All the students of grade 2015 in Changchun Medical College who were interned in the hospital from July 2016 to April 2017 were selected as the study objects,all student nurses were divided into the observation group (n=443)and control group (n=443)using the random sampling method.Student nurses in the observation group were trained using the introspection diary writing method,while those in the control group were trained by traditional hospital teaching method without requiring writing introspection diary.The nursing soft skill score of student nurses between the two groups were compared.Results After internship,the scores of self-management,cognitive skills,occupational sentiment,interpersonal relationship,organizational management and total scale of the two groups were significantly higher than those before internship (P＜0.05).The nursing soft skill scores of student nurses in the observation group were significantly higher than those of the control group (P＜0.05).Conclusion Introspection diary teaching method applied in clinical training of nursing students is helpful to improve their self-management,cognitive skills,professional sentiment,interpersonal relationship and organizational management ability,and it plays an important role in improving nursing soft skills of student nurses and further improving the clinical teaching quality. 2018 Vol. 25 (25): 164-166 [Abstract] ( 121 ) HTML (35 KB)  PDF  (0 KB)  ( 17 ) 167 Application of case teaching method in clinical teaching of gynaecology blood syndrome LI Xiao Case teaching method is a kind of new teaching method with strong interaction and participation,and it can mobilize medical students′subjective initiative and the ability of analyze and solve problems,it can improve the teaching level of teaching teachers and expand clinical teaching ideas.Case teaching method has strong clinical operability,and it takes gynecological blood syndrome as an example,and it is suitable for active promotion in clinical teaching of gynecology and obstetrics. 2018 Vol. 25 (25): 167-169 [Abstract] ( 135 ) HTML (32 KB)  PDF  (0 KB)  ( 26 ) 170 Effect clinical intervention of comprehensive nursing in neonatal jaundice nursing CHENG Yan-feng Objective To study the clinical effect of comprehensive nursing in neonatal jaundice nursing.Methods From January 2016 to December 2017,100 jaundice children who met the inclusion criteria and exclusion criteria of jaundice in our hospital were enrolled in this study,they were randomly divided into two groups by using the random number table method,50 cases in each group.The control group was given routine nursing,the observation group was given comprehensive nursing care.The jaundice treatment effect,incidence of adverse reactions,negative emotion score of parents and parents′satisfaction degree were compared between the two groups.Results The total effective rate in the observation group was 98%,which was higher than 84%that in the control group (P＜0.05）.The total incidence of adverse reaction in the observation group was 2%,was lower than the control group of 14% (P＜0.05）.After nursing,negative emotion scores (anxiety,depression score)in observation group were lower than those in control group (P＜0.05）.The total satisfaction rate of parents in the observation group was higher than that of the control group,the differences were statistically significant(P＜0.05）.Conclusion The comprehensive nursing during the neonatal jaundice treatment can effectively prevent jaundice in children,reduce adverse reactions,help to eliminate the negative emotions of parents,and make them more satisfied with the nursing work. 2018 Vol. 25 (25): 170-172 [Abstract] ( 99 ) HTML (35 KB)  PDF  (0 KB)  ( 25 ) 173 Effectiveness of upper limb functional extension test in predicting the risk of falls in elderly hospitalized patients SUN Jia-ze Objective To study the effectiveness of upper limb functional extension test(FRT)in predicting the risk of falls in elderly hospitalized patients.Methods 100 elderly patients who were admitted to our hospital from October 2016 to March 2017 were selected as subjects.According to the history of falls in the past year,the subjects were divided into fall history group and non-fall history group,50 cases in each group.Both groups were underwent FRT and five sit-up test(FTSST)to predict the risk of falling in the same time period.The two groups were compared in age,gender,FRT distance and FTSST time.The difference between body mass index (BMI)and the effectiveness of FRT and FTSST were compared by the modified Morse fall risk score.Results After testing,the FRT score of the fall history group was significantly higher than that of the non-fall history group.The FTSST of the fall history group was significantly lower than that of the non-fall history group(P＜0.05）,and the Morse fall risk score of the FRT was 87.5%.The TMorse fall risk score of FTSS was 71.88,the difference was statistically significant(P＜0.05）.Logistic regression analysis showed that the distance of FRT was significantly associated with the risk of falls (OR：1.3903).Conclusion FRT is a simple and time-saving functional testing tool that can effectively screen the risk of falls in the elderly and is worthy of clinical promotion. 2018 Vol. 25 (25): 173-176 [Abstract] ( 110 ) HTML (40 KB)  PDF  (0 KB)  ( 28 ) 177 Effectiveness of application of high quality nursing in operation room CAI Yu-fen Objective To analyze the effectiveness of application of high quality nursing in operation room.Methods Altogether 60 cases of patients who underwent surgeries in our hospital from January to December 2016 were selected as the subjects of this research and divided into the control group and the study group respectively according to pre and post high quality nursing.In the control group,traditional routine nursing was used during operation;while,high quality nursing was used in the study group.The heart rate,blood pressure,anxiety scale,postoperative satisfaction and the incidence of pre-and post-operational adverse reactions were compared between the two groups.Results There was no statistically significant difference in pre-operational heart rate,blood pressure and anxiety scale between the two groups(P＞0.05）.The post-operational anxiety scale of the two groups was significantly lower than that before the operation(P＜0.05）,which of the study group was far lower than that of control group (P＜0.05）.The post-operational heart rate and blood pressure of the two groups were more stable than those before the operation (P＜0.05）,which of the study group were far superior to the control group (P＜0.05）.The total satisfaction of nursing service of the study group was significantly higher than that of the control group,and the total incidence of adverse reactions was significantly lower than that of the control group,both with statistically significant difference(P＜0.05）.Conclusion The implementation of high quality nursing measures in the operation room is beneficial to the post-operational recovery of patients′various indexes,which can also reduce the degree of anxiety and the incidence of adverse reactions,and improve their satisfaction with the nursing service. 2018 Vol. 25 (25): 177-179 [Abstract] ( 125 ) HTML (36 KB)  PDF  (0 KB)  ( 28 ) 180 Application effect of rapid rehabilitation nursing in patients undergoing cholecystectomy DENG Dong-qin Objective To investigate the effect of rapid rehabilitation nursing on preoperative bad emotions and postoperative recovery in patients undergoing cholecystectomy.Methods 120 patients undergoing cholecystectomy from June 2014 to June 2016 in our hospital were selected.They randomly were divided into control group and observation group,60 cases in each group.In the control group,traditional nursing model was used,while in the observation group,rapid rehabilitation nursing was adopted.By observing self-rating anxiety scale (SAS)score,self-rating depression(SDS)score,borygmus recovery time,anal exhaust time,infusion time,hospital stay and incidence of complications and other related indicators,we analyzed the rapid rehabilitation care on the preoperative bad emotions and postoperative rehabilitation in patients with cholecystectomy.Results After nursing,there was no significant difference in the operation time between the two groups(P＞0.05）.The postoperative off-bed activity time,anal exhaust time,and hospital stay were all shorter in the study group than in the control group with statistical significance (P＜0.05）.In the study group,the SDS score and SAS score were both lower than those in the control group with great differences (P＜0.05）.In the study group,the total incidence of complications was 6.67%,lower than that in the control group accounting for 26.67%,with a significant difference (P＜0.05）.Conclusion The rapid rehabilitation surgical nursing provides good help for the recovery of postoperative patients and reduces the incidence of postoperative complications. 2018 Vol. 25 (25): 180-182转185 [Abstract] ( 120 ) HTML (38 KB)  PDF  (0 KB)  ( 7 ) 183 Application of guided education in rehabilitation treatment of cerebral palsy in children ZHANG Liang;LIU Yan-ping Objective To explore the effect of guiding education in rehabilitation treatment of cerebral palsy（CP）in children.Methods80 cases of infantile CP children in our hospital From January 2014 and January 2017 were selected as research object,which randomly divided into normal group and experimental group,40 cases in each group.The normal group was given conventional rehabilitation,the experimental group was given conventional rehabilitation treatment+heuristic education.All the patients were followed up for one year,and the gross motor function scale(GMFM)score,daily life activity ability(ADL)score,social adaptability score and satisfaction degree of the children were compared between two groups.Results After treatment,GMFM score (95.24±10.78)was higher in the experimental group than that in the conventional group(68.78±12.23),and the difference was statistically significant(P＜0.05）.Experimental ADL scores after treatment in children with (61.24±12.98),social adaptation ability score (4.24±1.78)points were higher than that in the conventional group （[50.95±12.23],[3.01±1.25]）,the differences were statistically significant(P＜0.05）.Conclusion It is feasible to guide education for children with CP and can improve their motor function. 2018 Vol. 25 (25): 183-185 [Abstract] ( 103 ) HTML (32 KB)  PDF  (0 KB)  ( 27 ) 186 Application effect of psychological nursing in hysterectomy patients WANG Rong Objective To explore the effect of psychological nursing in hysterectomy patients.Methods 50 patients who underwent hysterectomy in our hospital from July 2015 to October 2017 were selected as the subjects.They were divided into the control group and the observation group according to difference nursing mode.The control group was treated with routine nursing,and the observation group was treated with psychological nursing intervention on the basis of the control group.The visual analogue score(VAS)and the Zung′s anxiety and depression scale were used to determine the pain degree and psychological state of the two groups before and after nursing,and the quality of life in the two groups was compared.Results The pain score of the control group was(5.1±0.8)points,the anxiety score (58.6±1.8)points,the depression score(62.5±2.8)points,the pain score of the observation group(3.6±0.6)points,the anxiety score(49.2±2.1)points,and the depression score (54.6±3.2)points,and the score of the depression (54.6±3.2)points.The abovementioned score of the observation group were significantly lower than that of the control group (P＜0.05）.The quality of life in the observation group was significantly better than that in the control group,the differences were statistically significant(P＜0.05）.Conclusion Psychological nursing intervention can reduce pain and improve negative emotions in patients with total hysterectomy,and it can improve the quality of life of patients,and is worthy of popularization and application. 2018 Vol. 25 (25): 186-188 [Abstract] ( 114 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 189 The result of family nursing intervention for ADHD children by using eight step correction ZHAO Hong-wei;LI Jie Objective To approach result of family nursing intervention for ADHD children by using eight step correction.Methods 68 cases clinical data of ADHD children in our hospital from July to December 2017 were analyzed,which was divided into the controi group and the detection group by random paper method,34 cases in each group.The control group was given basic treatment and the detection groupwas given eight step correction.The comprehensive control quotient,comprehensive attention quotient,visual control quotient， visual attentional quotient， auditory control quotient，auditory attentional quotient,hearing correct number,visual correct number,visual reaction time,auditory reaction time,vestibular balance,tactile excessively defensive state and emotional instability,proprioception maladjustment,learning ability development lack of two group ADHD children before intervention and after intervention were detected.ResultsThe comprehensive control quotient,comprehensive attention quotient,visual control quotient,visual attentional quotient， auditory control quotient， auditory attentional quotient,hearing correct number,visual correct number,visual reaction time,auditory reaction time,vestibular balance,tactile excessively defensive state and emotional instability,proprioception maladjustment,learning ability development lack of two group ADHD children before intervention were no difference(P＞0.05）,the comprehensive control quotient,comprehensive attention quotient,visual control quotient,visual attentional quotient,auditory control quotient,auditory attentional quotient,hearing correct number,visual correct number,auditory reaction time,vestibular balance,tactile excessively defensive state and emotional instability,proprioception maladjustment,learning ability development lack of two group ADHD children after intervention were higher than before intervention in the same group,the comprehensive control quotient,comprehensive attention quotient,visual control quotient,visual attentional quotient,auditory control quotient,auditory attentional quotient,hearing correct number,visual correct number,auditory reaction time,vestibular balance,tactile excessively defensive state and emotional instability,proprioception maladjustment,learning ability development lack of detection group after intervention were higher than that in the control group,the differences were statistical significance(P＜0.05）.Conclusion The application of ADHD by eight step correction,which could improve IVA-CPT and SIFS,it is worth to be used. 2018 Vol. 25 (25): 189-191转195 [Abstract] ( 107 ) HTML (35 KB)  PDF  (0 KB)  ( 29 ) 192 Application result of Congenital heart disease children in interventional therapy by special nursing intervention ZHANG Qi-mei;YE Dong-mei;LAI Bo-cong;YANG Wen-lin Objective To approach application result of Congenital heart disease （CHD） children in interventional therapy by special nursing intervention.Methods 91 cases clinical data of CHD children in Guangdong province traditional Chinese hospital from July 2016 to December 2017 were analyzed,which was to be divided into two group by different nursing,regular group 40 cases and strengthened group 51 cases.The nursing errors rate paediatric patients family of satisfaction and operation doctors of satisfaction for two group children were detected.Results The nursing errors rate of strengthened group were lower than regular group,the paediatric patients family of satisfaction and operation doctors of satisfaction for strengthened group were higher than regular group,The preoperative preparation,tracheal intubation nursing,indwelling tube administration,Intraoperative coordination,inspection after operation,complications after operation for nursing work quality score of strengthened group were higher than regular group,the difference were statistical significance(P＜0.05）.Conclusion In pediatric interventional treatment of CHD,preoperative preparation is complete,the skilled operation coordination,intraoperativecoordination in place,intraoperative emergency prepare to provide high quality nursing service,to ensure the operation is completed. 2018 Vol. 25 (25): 192-195 [Abstract] ( 125 ) HTML (37 KB)  PDF  (0 KB)  ( 24 ) 196 Effect of nursing intervention on the quality of midwifery and postpartum hemorrhage ZHANG Xiao-na;CHEN Li-jie;WU Jie-ying Objective To investigation effect of different nursing methods on midwifery quality and postpartum hemorrhage.Methods 80 cases of puerpera treated in Maternal and Child Health Family Planning Service Center of Rucheng District from May 2015 to May 2017 were selected,and they were divided into control group and observation group by computer grouping mode,40 cases in each group.The observation group was given intervention nursing,the control group was given routine care.The two groups of pregnant women were compared with the labor conditions,hemorrhage,cesarean section rate,and satisfaction with medical staff.Results The first stage of labor in the observation group was(402.65±8.95)min,the second stage of labor was(25.76±2.11)min,the third stage of production was(5.86±1.05)min,and the total stage of labor was(456.85±6.98)min,were shorter than that in the control group,the first stage of labor was(416.89±15.68)min,the second stage of production was(53.98±5.44)min,the third stage of production was(7.95±1.62)min,and the total stage of labor was(675.41±9.76)min(P＜0.05）;2 hours postpartum hemorrhage in the observation group was(186.42±15.75)ml,and postpartum 24 hours bleeding was (256.85±26.95)min,and the rate of major bleeding was 5.00%,which were lesser than that of the control group,the postpartum hemorrhage at 2 hours was(254.17±26.97)ml,and the postpartum hemorrhage at 24 hours was(394.19±42.81)min;the rate of major bleeding was 32.50%(P＜0.05）;the service satisfaction score of the observation group was([96.85±1.33]points),the service quality score was[97.38±1.43]points,and the service satisfaction score of the mothers in the control group was([86.17±2.11]points),and the service quality score was([85.23±1.63]points),compliance was （P＜0.05）;social function score in observation group was([95.86±2.33]points),material life([96.83±1.74]points),physical function score was([96.85±1.77]points),and psychological function score was([97.11±1.58]points)were higher than those of the control group([86.58±2.44]points)and material life([87.95±1.75]points),physical function([88.41±1.53]points),and psychological function([85.69±1.75]points),the differences were statistically significant(P＜0.05）.Conclusion The nursing intervention for the parturient woman can shorten the birth process,reduce the bleeding,reduce the cesarean section rate and improve the quality of life,so as to improve the satisfaction degree of the medical staff.It is worth promoting in the clinic. 2018 Vol. 25 (25): 196-198转202 [Abstract] ( 117 ) HTML (38 KB)  PDF  (0 KB)  ( 30 ) 199 The effect of root cause analysis on the function recovery of total hip arthroplasty in old age ZHANG Fan Objective The effect of root factor analysis （RCA）on functional recovery of total hip arthroplasty in elderly patients was studied.Methods From January 2015 to January 2017,72 elderly patients undergoing total hip replacement were selected and divided into the control group and the treatment group,according to random number table method.The control group was received routine nursing,the treatment group was adopted RCA method on the basis of routine nursing,the medical staff solved the problem according to the specific situation of each patient,and took psychological intervention,health guidance,complications,etc.Nursing care in rehabilitation training of affected limbs and joints.The difference between the two groups after hip operation was evaluated,the Barthel index and depression score of daily life were evaluated,and the incidence of postoperative complications was observed.Patients′satisfaction with nursing was investigated by questionnaire.Results The scores of pain,function,range of motion and total score of Harris of hip joint in the treatment group were higher than those in the control group (P＜0.05）;The Barthel index of the treatment group was higher than that of the control group,and the score of GDS depression scale in the treatment group was lower than that in the control group (P＜0.05）;The total incidence of postoperative complications in the treatment group was lower than that in the control group (P＜0.05）;The total satisfaction of the patients in the treatment group was higher than that in the control group (P＜0.05）.Conclusion Postoperative geriatric total hip arthroplasty with RCA has played a good therapeutic effect on the recovery of the total hip arthroplasty,relieving the symptoms,improving the daily living ability of patients,and controlling the increase of patients′depression rate. 2018 Vol. 25 (25): 199-202 [Abstract] ( 110 ) HTML (42 KB)  PDF  (0 KB)  ( 28 ) 203 Effect of continued psychological nursing intervention on the patients receiving cervical cancer surgery and the emotions of their family members GUI Fang Objective To investigate the effect of continued psychological nursing intervention on the patients receiving cervical cancer surgery and the emotions of their family members.Methods 60 patients undergoing cervical cancer surgery who were admitted to our hospital from January 2016 to December 2017 were selected.They were randomly divided into control group and observation group,30 cases in each group.The control group was given telephone followup.On the basis of telephone follow-up,the patients and their family members in the observation group were given continued psychological nursing intervention.The anxiety,depression and quality of life after nursing satisfaction with nursing works were compared between the two groups of patients.Results After continued psychological nursing intervention in the observation group,the anxiety and depression in the patients and their family members were significantly lower than those in the control group (P＜0.05）.The quality of life in the observation group and total satisfaction with nursing works were significantly higher than those in the control group (P＜0.05）.Conclusion The continued psychological nursing intervention for the patients receiving cervical cancer surgery can improve the negative emotions of anxiety and depression in patients and their families,and improve the quality of life. 2018 Vol. 25 (25): 203-205 [Abstract] ( 107 ) HTML (35 KB)  PDF  (0 KB)  ( 29 ) 206 Continuous nursing to improve the self-care ability and in the role of glycemic control of patients with diabetes at home ZHOU Ting Objective To investigate the continuous nursing in improving the self-care ability of patients with senile diabetes (DM)at home and glycemic control in effect.Methods 96 elderly patients with type 2 DM treated in our hospital from March 2016 to March 2017 were selected as the subjects.The patients were divided into the control group and the observation group according to the random number table method,48 cases in each group.The control group patients after discharge regularly were review,observation group patients after were discharge continuous nursing plan.The self-care ability and blood glucose control before and after intervention were compared between the two groups.Results There was no significant difference in the scores of the two groups before intervention(P＞0.05）,and the scores of all the two groups after intervention were improved,and the observation group was significantly higher than that in the control group(P＜0.05）.After intervention,the two groups of fasting blood glucose（GLU）,postprandial blood sugar and glycated hemoglobin （GHb） were all decreased,and the observation group was significantly lower than that in the control group,the differences were statistically significant(P＜0.05）.Conclusion Continuous nursing can effectively improve the self-management ability of elderly DM patients,improve their blood sugar control outside the hospital. 2018 Vol. 25 (25): 206-208 [Abstract] ( 134 ) HTML (33 KB)  PDF  (0 KB)  ( 27 ) 209 Application effect of whole-course nursing on patients performed with ultrasound-guided transrectal prostate biopsy CHEN Dong-mei;CHEN Yong-wen;2ZHUO Tao;QIAN Chong Objective To analyze the application effect of whole-course nursing on patients performed with transrectal prostate biopsy under ultrasound guidance.Methods A total of 120 patients with prostate lesions admitted to our hospital from June 2015 to January 2017 were selected as subjects.All patients underwent transrectal prostate biopsy under ultrasound guidance.The patients were equally divided into two groups according to the odd or even number,60 cases in each group.The patients treated with the traditional nursing model were classified into traditional group.On this basis,the patients provided with the whole-course nursing as cooperation were categorized into whole group.The scores of psychological status like self-rating anxiety scale(SAS)and self-rating depression scale(SDS),blood pressure(diastolic blood pressure and systolic blood pressure)levels before and after intervention in these two groups were compared and analyzed,and the nursing compliance and nursing satisfaction of the two groups were observed.Results There was no significant difference in the scores of psychological indicators before intervention between the two groups(P＞0.05）.The SAS and SDS scores after the intervention in the whole group were lower than those in the traditional group,with statistical significance (P＜0.05）.Before intervention,there was no significant difference in blood pressure levels between the two groups(P＞0.05）.The diastolic blood pressure and systolic blood pressure after intervention in the whole group were both lower compared to those in the traditional group(P＜0.05）.The scores of nursing compliance and nursing satisfaction scores were higher than those in the traditional group,with statistical significance (P＜0.05）.Conclusion During ultrasound-guided transrectal prostate biopsy,the implementation of whole-course nursing as cooperation can effectively alleviate the negative emotions and improve nursing satisfaction,which is worthy of recommendation and application. 2018 Vol. 25 (25): 209-211 [Abstract] ( 114 ) HTML (37 KB)  PDF  (0 KB)  ( 28 ) 212 Application effect of comprehensive nursing intervention in elderly patients with coronary heart disease ZHANG Ya-qiong;WANG Nan-li Objective To explore the effect of comprehensive nursing intervention program on improving the quality of life of elderly patients with coronary heart disease.Methods From December 2016 to February 2018 period,One hundred patients with senile coronary artery disease who were treated in our department of cardiology were selected.They were divided into experimental group and control group according to random number table method,50 cases in each group.Routine nursing intervention program was administered to the control group patients.A comprehensive nursing intervention program was implemented on the basis of routine nursing care to compare the quality of life,social support,and psychological status of the two groups.Results The scores of quality of life,scores of scale,social support scale and scores of all dimensions in the experimental group were higher than those in the control group.SAS score and SDS score were lower than the control group,and the differences were statistically significant(P＜0.05））.Conclusion The comprehensive nursing intervention program can improve the quality of life,social support,and improve the mental health status of elderly patients with coronary heart disease.It is worthy of promotion and application in clinical practice. 2018 Vol. 25 (25): 212-214 [Abstract] ( 108 ) HTML (33 KB)  PDF  (0 KB)  ( 35 ) 215 Effects of high-flow nasal cannulae in ICU patients with tracheal intubation after extubation LUO Yan;DENG Hong-mei Objective To explore the effect of high flow oxygen humidification treatment in ICU patients with tracheal intubation after extubation,and to provide reference for effective nursing of ICU tracheal intubation patients after extubation.Methods Totally 80 ICU patients with tracheal intubation after extubation from May 2016 to October 2017 were selected and divided randomly in the control group and the experimental group,40 cases in each group.The control group was treated with conventional oxygen therapy,and the experimental group was treated with high flow oxygen humidification oxygen therapy.The incidence of the injury of trachea mucosa,lung infection,and reintubation were compared between the two groups,as well as the effect of ventilation.Results The incidence of tracheal mucosa injury,pulmonary infection and reintubation in the experimental group was significantly lower than that of the control group (P＜0.05）.After extubation 24 h,PaO2,PaCO2and BE in the experimental group were better than those in the control group,the differences were statistically significant(P＜0.05）.Conclusion High flow oxygen humidification treatment can significantly reduce the incidence of respiratory complications and reintubation in ICU patients with tracheal intubation after extubation,and improve ventilation effect. 2018 Vol. 25 (25): 215-217 [Abstract] ( 112 ) HTML (35 KB)  PDF  (0 KB)  ( 26 ) 218 Application of comfortable nursing in perioperative period of laparoscopic myomectomy JIANG Yun-he;JIANG Yun-fei Objective To explore the effect of comfortable nursing on laparoscopic myomectomy.Methods 40 cases of laparoscopic myomectomy in our hospital from April 2016 to February 2018 were selected as the subjects.The sampling methods were divided into the observation group 20 cases and the control group 20 cases.The control group was adopted the traditional nursing method and the observation was group adopted the comfortable nursing method.The operative time,the total incidence of complications and nursing satisfaction of the two groups were compared.Results The operation time of the observation group was(96.15+2.84)min,and the operation time of the control group was(98.05+2.37)min.The difference of the operation time of the two groups was not statistically significant(P＞0.05）.The total incidence of complications in the observation group was lower than that of the control group(P＜0.05）,and the very satisfactory rate and total satisfaction of the observation group were higher than those of the control group,the differences were statistically significant(P＜0.05）.Conclusion Comfortable nursing can reduce postoperative complications,improve the rate of nursing satisfaction and nursing satisfaction. 2018 Vol. 25 (25): 218-220 [Abstract] ( 115 ) HTML (34 KB)  PDF  (0 KB)  ( 27 )

Copyright © Editorial Board of 中国当代医药 Supported by:Beijing Magtech