温敏脂质体作为肿瘤靶向递药载体的研究进展

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Abstract Thermosensitive liposome is a new targeted drug carrier.The thermosensitive liposome is used as a carrier to encapsulate an anti-tumor drug,which can be distributed to tumor tissues on targeting by utilizing an enhanced permeability and retention effect of the tumor tissue.After that,the drugs in the carrier will be released into tumor tissues once triggered by local external heating,which can improve the drug targeting,reduce systemic side effects,and achieve combined therapy of tumor thermochemotherapy.In this research,the related literature at home and abroad in recent years and the studies of thermosensitive liposomes as tumor-targeted drug delivery carriers were reviewed.As a tumor-targeted drug carrier,thermosensitive liposome has a good prospect.

Key words： Thermosensitive liposome Tumor targeting Drug delivery carrier

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	Articles by authors
	ZHU Xia-li
	LI Ling-hua
	HUANG He-qing
	TIAN Xiao-zhi
	JIA Yong-yan

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ZHU Xia-li,LI Ling-hua,HUANG He-qing, et al. Research progress of thermosensitive liposomes as a tumor-targeting drug delivery carrier[J]. 中国当代医药, 2018, 25(25): 31-34.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I25/31

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