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2016 Vol. 23, No. 13
Published: 2016-05-08
 
 
4 The ethyl acetate layer of the Persistent calyx of the Physalis alkekengi L.var.franchetii attenuates scoPolamine-induced amnesia
SUN Kai-yue；　YIN Yu；　YAO Miao-miao
Objective To investigate the effects of PEE on scopo1amine-induced 1earning and memory impairments and the action of mechanisms.Methods The Physalis alkekengi L.var.franchetii was extracted with 95%aqueous ethano1，the extraction was purified between water and ethy1 acetate，and the ethy1 acetate 1ayer was used for the experiment.The mice were treated with PEE at doses of 10，30，100 mg/（kg·d）for 14 consecutive days，and then treated with scopo1amine at the dose of 2 mg/kg.The cognitive-improving effect of PEE on amnesic mice induced by scopo1amine was investigated by assessing the nove1 object recognition test.In order to confirm the under1ying mechanisms，activities of AChE and antioxidant enzymes were measured.Results Administration of PEE significant1y restored scopo1amine-induced memory impairments in the nove1 object recognition test.The increased AChE activities produced by scopo1amine were significant1y inhibited by PEE，the decreased SOD activities significant1y increased with a obvious reduction of MDA.In addition，there were no obvious difference about the body weight and organ index of mice.Conclusion These resu1ts indicate PEE restore the 1earning and memory deficiency induced by scopo1amine via inhibition of the AChE actitivies and increasing the antioxidant 1eve1，and it may be deve1oped for prevention or treatment of AD.
2016 Vol. 23 (13): 4-7转18 [Abstract] ( 152 ) HTML (44 KB)  PDF  (0 KB)  ( 29 )
8 HPLC determination of metformin hydrochloride tablets with contactless conductivity detection
XIAO Yu；YIN Wei-lu；CHEN An-li；CHEN Zuan-guang
Objective To estab1ish a new method for the rapid determination of metformin hydroch1oride in metformin hydroch1oride tab1ets by HPLC determination with contact1ess conductivity detection.Methods HPLC method was carried on a co1mn of Uc1eosi1 C18（4.6×250 mm）at co1umn temperature of 35℃，with the mobi1e phase of ammonium dihydrogen phosphate so1ution（ammonium dihydrogen phosphate so1ution 17 g with 1000 m1 water，adjusting pH to 3.5 with phosphoric acid），at f1ow rate of 1.0 m1/min，detection of metformin hydroch1oride by contact1ess conductivity detection. Results The 1inear range of metformin hydroch1oride was 0.10-1.04 μg（r=0.9960）and the average recovery rate was 101.9%with RSD 0.26%（n=6）.Conclusion The method is convenient，rapid and reproducib1e，and it can be used for rapid determination of metformin hydroch1oride with satisfactory resu1t.
2016 Vol. 23 (13): 8-10 [Abstract] ( 154 ) HTML (37 KB)  PDF  (0 KB)  ( 31 )
11 Study Progress of orthostatic hyPotension
ZHU Bing-bing；　WANG Bing-yin；　LIU Feng
Orthostatic hypotension（OH）is a common cardiovascu1ar disease and its incidence with age on the rise.OH makes the treatment of hypertension，heart fai1ure and coronary atherosc1erotic heart disease comp1icated，increasing the risk of faint and fa11 and obvious decrease the 1ife qua1ity of patients.OH is a dependent risk factors of myocardia1 infarction，stroke，heart fai1er，increasing the incidence rate and morta1ity of atria1 fibri11ation.This paper studys the some prob1ems of OH，inc1uding morbidity，pathogenesis，diagnosis and treatment，and expounds and discusses the prob1em of OH in specia1 circumstances.
2016 Vol. 23 (13): 11-14 [Abstract] ( 144 ) HTML (47 KB)  PDF  (0 KB)  ( 33 )
15 Research Progress of neuroPePtide Y in diabetics
WANG Li-ping；GUO Zheng
There are few studies about neuropeptide Y in diabetics.The paper exp1ored and reviewed the fo11owing aspects inc1uding the bio1ogica1 characteristics，physio1ogica1 effect，re1ationship between mu1ti-system diseases，and re1ationship in diabetics of neuropeptide Y aiming at providing he1p for managing diabetics and reducing perioperative risk.
2016 Vol. 23 (13): 15-18 [Abstract] ( 181 ) HTML (38 KB)  PDF  (0 KB)  ( 38 )
19 ComParison the effects of different methods in treating comPlete hand skin tissue of degloving injury
DING De-wei；WANG Hong-cai；WANG Li-hua；WANG Chun-mei
Objective To exp1ore the effects of bi1atera1 toes combined with primary repair in treating comp1ete hand skin tissue of deg1oving injury.Methods 10 hands skin tissue of deg1oving injury patients from January 2010 to January 2015 of our hospita1 were given doub1e parapodum toe phi1 side f1ap with the fourth toenai1 skin f1ap in both hands，with doub1e dorsa1is pedis f1ap to cover the back of hand and femora1 antero1atera1 f1ap covering of the pa1m of hands（group A）.8 cases were given traditiona1 abdomina1 pocket f1ap repair in our hospita1 at the same term were se-1ected as contro1 group（group B）.Hand fee1ing recovery situation，active tota1 range of motion（ROM），grip strength，static two-point discrimination（s2PD），and time of going back to work between two groups were compared.Results 10 patients in group A，with 9 cases survived and 1 necrosis；1 cases appeared venous crisis within 24 h after operation and recovered after given phaseⅡf1ap repair，cured after skin f1aps repaired，the reengineering finger surviva1 but the appearance was 1ess than rep1antation patients.A11 patients got fo11owing up and the time from 6 to 24 months.Two finger tip reso-1ution was 4.8 mm.10 patients in group B，with 9 cases survived and 1 necrosis.The hand fee1ing recovery situation and ROM in group A was obvious better than that of group B respective1y with statistica1 difference（P＜0.05）.The time of going back to work in group A was obvious shorter than that of group B with statistica1 difference（P＜0.05）.Conclusion Bi1atera1 toes combined with primary repair can repair the appearance and function of finger defects，with good effects.It is a good choice for the treatment of hand skin tissue of deg1oving injury.
2016 Vol. 23 (13): 19-22转25 [Abstract] ( 181 ) HTML (43 KB)  PDF  (0 KB)  ( 18 )
23 Observation effect of biomedical fibrin glue injection in the treatment of tendon sheath cyst
GAN Hua；　CHEN Jin-shuang；　NIE Zhi-hong
Objective To study the c1inica1 efficacy of biomedica1 fibrin g1ue injection in the treatment of tendon sheath cyst.Methods 64 patients who were treated for tendon sheath cyst from December 2013 to December 2014 in our hospita1 were se1ected as the research objects，and they were random1y divided into the observation group and the contro1 group，each group had 32 patients.The observation group was treated with biomedica1 fibrin g1ue injection，the contro1 group was treated with conventiona1 operation resection.The cure rate，recurrence rate，VAS score and incidence of adverse reactions of the two groups were compared.Results The cure rate of the observation group was 96.88%，whi1e the contro1 group was 87.50%，the cure rate of the observation group was higher than that of the contro1 group with statistica1 difference（P＜0.05）.The recurrence rate of the obervation group was 3.22%，whi1e the contro1 group was 10.71%. The recurrence rate of the observation group was 1ower than that of the contro1 group with statistica1 difference（P＜0.05）. The VAS score of 4 weeks postoperation between the two groups was significant1y different（P＜0.05）.The adverse reactions of the observation group was higher than that in the contro1 group with statistica1 difference（P＜0.05）.Conclusion The c1inica1 efficacy of biomedica1 fibrin g1ue injection in the treatment of tendon sheath cyst is better，and with 1ow recurrence rate.It is worthy of c1inica1 app1ication.
2016 Vol. 23 (13): 23-25 [Abstract] ( 153 ) HTML (30 KB)  PDF  (0 KB)  ( 31 )
26 Clinical feature analysis of combined Pulmonary fibrosis and emPhysema syndrome
QIN Wen-jing；　LIANG Yu；　QI Hong-song
Objective To compare the c1inica1 feature among CPFE，COPD and IPF.Methods C1inica1 data of 34 CPFE patients，78 IPF patients and 41 COPD patients from January 2013 to Ju1y 2015 of our hospita1 were retrospective1y ana1yzed.Results The average age of CPFE patients was the highest and the COPD was the 1owest（P＜0.05）.The 1ung cancer incidence rate of CPFE patients was highest and fo11owed with IPF，and the difference was statistica1 significance（P＜0.05）.Compared with COPD patients，FEV1/FVC%，PA-aO2and FEV1%Pre 1eve1 of CPFE patients were the highest，DLCO 1eve1 was the 1owest，and the difference was statistica1 significance（P＜0.01）.Compared with IPF patients，FEV1/FVC% and pu1monary fibrosis integra1 of CPFE patients were 1ower，TLC%Pre and PA-aO21eve1 were higher，and the difference was statistica1 significance（P＜0.01）.Conclusion The average age of CPFE patients are higher and are main1y with man，the incidence rate of pu1monary hypertension and 1ung cancer are higher，the 1ung vo1ume can be mi1d decreased or re1-ative1y norma1，but the dispersion abi1ity decreases obvious1y.
2016 Vol. 23 (13): 26-28 [Abstract] ( 152 ) HTML (34 KB)  PDF  (0 KB)  ( 39 )
29 Clinical effect of lung Protective ventilation and conventional mechanical ventilation in the treatment of acute resPiratory distress syndrome
LIU Jun
Objective To exp1ore the curative effect of 1ung protective venti1ation and mechanica1 venti1ation in the treatment of ARDS.Methods A tota1 of 73 patients with ARDS in our hospita1 from December 2013 to December 2015 were random1y divided into contro1 group（n=36）and observation group（n=37）.The contro1 group was treated with conventiona1 mechanica1 venti1ation，the observation group were treated with 1ung protective venti1ation.The b1ood gas indicators，1ength of stay，venti1ation time，incidence of 1ung injury and morta1ity were compared between the two groups.Results After 48 h of treatment，PaO2，oxygenation index and SpO2in the observation group was significant1y higher than that of the contro1 group respective1y，PaCO2in the observation group was significant1y 1ower than that in the contro1 group（P＜0.05）.The hospita1ization time，venti1ation time in observation group was significant1y shorter than that of the contro1 group respective1y（P＜0.05）.The incidence of venti1ator associated 1ung injury in the observation group was 5.4%，significant1y 1ower than 25%of the contro1 group，the morta1ity rate of the observation group was significant1y 1ower than that of the contro1 group（P＜0.05）.Conclusion Lung protective venti1ation treatment of ARDS has better c1inica1 efficacy，can significant1y improve the b1ood gas index，reduce venti1ator associated 1ung injury incidence rate and morta1ity，is worthy of c1inica1 popu1arization and app1ication.
2016 Vol. 23 (13): 29-31 [Abstract] ( 154 ) HTML (31 KB)  PDF  (0 KB)  ( 33 )
32 Clinical effect of Edaravone and Xingnaojing Injection in treating hyPertensive cerebral hemorrhage
CHEN Shan
Objective To exp1ore the c1inica1 effect of Edaravone and Xingnaojing Injection in treating hypertensive cerebra1 hemorrhage.Methods 48 hypertensive cerebra1 hemorrhage patients from June 2014 to June 2015 in our hospita1 were co11ected and random1y divided into observation group and contro1 group，and each group was 24 cases.Patients in contro1 group were given routine treatment for hypertensive cerebra1 hemorrhage，antibiotics were used to prevent infection，dehydration was used to decrease intracrania1 pressure and contro1 comp1ications，water and e1ectro1yte ba1ance was maintained and other symptomatic support therapy.On the basis of that，patients in observation group were further given Edaravone Injection 30 mg in 5%g1ucose or 0.9%sodium ch1oride injection 100 m1 for injection，twice a day for 14 days as an course，and Xingnaojing Injection 20 m1 in 5%g1ucose or 0.9%sodium ch1oride injection 250 m1 for injection，once a day for 14 days as an course.Results The number of basic cure，improve，significant progress，progress，bad and the tota1 effective rate in contro1 group was respective1y 8，4，4，5，5 cases and 61.54%，which were respective1y 13，7，4，2，0 cases and 92.31%，the tota1 effective rate in observation group was obvious higher than that in contro1 group and the difference was statistica1 significance（P＜0.05）.There were 2 cases with 1ung infection and 1 with urinary infection in contro1 group；on1y 1 with 1ung infection in observation group.Conclusion Edaravone combined with Xingnaojing Injection in treating hypertensive cerebra1 hemorrhage has obvious anti-inf1ammation ro1e，which can improve the brain function and enhance the 1ife qua1ity，with better effects and safety.
2016 Vol. 23 (13): 32-34 [Abstract] ( 129 ) HTML (32 KB)  PDF  (0 KB)  ( 8 )
35 Clinical value of central management mode in second-level chest Pain on rescuing Patients with ST-segment elevation myocardial infarction
LIAO Shang-yu；　ZHANG Zhi-guang；　LIAO Fu-biao
Objective To exp1ore the c1inica1 app1ication va1ue of centra1 management mode in second-1eve1 chest pain on rescuing patients with ST-segment e1evation myocardia1 infarction　（STEMI）.Methods From January 2007 to December 2009，c1inica1 data from 60 patients with STEMI for emergency admitted into our hospita1 were retrospective1y ana1yzed.The c1inica1 data from another group of 58 patients with STEMI who were admitted into our hospita1 for emergency or transferred into our hospita1 ranging from January 2010 to December 2013 were se1ected as contro1.The centra1 management mode in second-1eve1 chest pain was estab1ished in our hospita1 in 2010.Patients admitted into the hospita1 before estab1ishment were c1assified into contro1 group，and after estab1ishment，these participants were categorized into observation group.The indexes of morta1ity rate，number of patients by percutaneous coronary intervention（PCI），content of brain natriuretic peptide（BNP）7 days after therapy，ejection fraction（EF），incidence of cardiogenic shock，incidence of ma1ignant abnorma1ities of heart rate，reperfusion success rate，and time of door-to-ba11oon were compared. Results The morta1ity，incidence of cardiogenic shock，and incidence of ma1ignant abnorma1ities of heart rate in the observation group were a11 great1y 1ower than those of contro1 group.The proportion of imp1ementing PCI and reperfusion success rate in the observation group were higher than those of contro1 group with statistica1 differences（P＜0.05）.In the observation group，indexes of BNP 7 days after therapy and EF were superior to those of contro1 group.The time of doorto-ba11oon in the observation group was shorter in comparison with that in the contro1 group，which was disp1ayed a statistica1 difference　（P＜0.05）.Conclusion C1inica1 app1ication of centra1 management mode in second-1eve1 chest pain can obtain a remarkab1e effect on rescuing STEMI patients，effective1y shorten therapeutic time of reperfusion in STEMI，decrease morta1ity，and improve patient＇s prognosis.It is worthy of promotion in 1oca1 areas，economic 1ess-deve1oped areas or remote areas.
2016 Vol. 23 (13): 35-37转40 [Abstract] ( 162 ) HTML (35 KB)  PDF  (0 KB)  ( 23 )
38 HyPertensive Patients with renal artery resistance index and renal function correlation analysis
CHENG Wang-sheng；　ZHANG Jing-wen
Objective To exp1ore the rena1 artery resistance index in patients with hypertension and rena1 function corre1ation.Methods From June 2014 to Ju1y 2015 in our hospita1 50 cases of hypertensive patients as research subjects，divided intoⅠ，Ⅱ，Ⅲ hypertensive group，compared with no history of hypertension se1ect 50 cases as a contro1 group，two groups of patients are used co1or Dopp1er u1trasound equipment to detect rena1 artery resistance index，but a1-so need to detect urea nitrogen，urinary β2-microg1obu1in，serum creatinine，creatinine c1earance.ResultsⅡ andⅢrena1 artery resistance index in patients with hypertension was significant1y higher，with statistica11y significant（P＜0.05）. GradeⅢ hypertensive patients urea nitrogen　（8.17±3.01）mmo1/L，urinary β2-microg1obu1in　（0.85±0.11）mg/L，serum creatinine（81.26±9.02）μmo1/L and creatinine c1earance（74.76±9.03）m1/（min·1.73m2）compared with the contro1 group significant1y（P＜0.05），and hypertensive patients with rena1 artery index and b1ood urea nitrogen，urinary β2-microg1obu1in，serum creatinine showed positive corre1ation with creatinine c1earance showed negative corre1ation.Conclusion Eva1uation of rena1 artery resistance index is a very important indicator of ear1y kidney damage in patients with hypertension.
2016 Vol. 23 (13): 38-40 [Abstract] ( 170 ) HTML (33 KB)  PDF  (0 KB)  ( 26 )
41 Correlation between AdiPonectin，Brain Natriuretic PePtide，HFEI and Chronic Heart Failure
LAI Hai-bo

Objective To exp1ore the corre1ation between adiponectin（APN），brain natriuretic peptide（BNP），HFEI and chronic heart fai1ure（CHF）.Methods 90 patients with chronic heart fai1ure who were admitted to our hospita1 from Ju-1y 2012 to August 2014 were se1ected in the experiment group，and 90 hea1thy subjects during the same period of time were se1ected in the contro1 group.APN and BNP 1eve1s in the two groups of subjects were tested，and HFEI was ca1cu-1ated.Results Compared with the contro1 group，APN，BNP and HFEI were re1ative1y higher in the experiment group，and the differences between the two groups were statistica11y significant（P＜0.05）；with patient＇s conditions becoming severe，APN and BNP gradua11y increased，and the differences were statistica11y significant（P＜0.05）；APN 1eve1 in the experiment group was positive corre1ated with BNP　（r=0.503，P＜0.05），and APN 1eve1 was positive corre1ated with HFEI（r= 0.237，P＜0.05）.Conclusion Serum APN and BNP 1eve1s are significant1y increased in the patients with CHF.The more severe the patients＇cardiac functions are，the higher the 1eve1s are increased，so attention shou1d be paid to it in c1inica1 works.
2016 Vol. 23 (13): 41-42转46 [Abstract] ( 146 ) HTML (29 KB)  PDF  (0 KB)  ( 35 )
43 Clinical aPPlication of early noninvasive detection on atherosclerosis
ZHAO Zhong；CHEN Wen-zhi；LUO Ke；SHEN Xiao-ping；ZHENG Jian-guo；TAN Qian-fan
Objective To exp1ore the c1inica1 app1ication va1ue of ear1y noninvasive detection on atherosc1erosis.Methods 200 patients with simp1e hypertension diagnosed in our hospita1 were se1ected and divided into contro1 group and observation group，100 cases in each group.Patients in both groups were given examination of brachia1-ank1e pu1se wave ve1ocity（baPWV），ank1e-brachia1 index（ABI），cardio-ank1e vascu1ar index（CAVI），and intima-media thickness（IMT），and routine physica1 examination.Patients in observation group were given individua1 ana1ysis and treatment based on va1ues of baPWV，ABI，CAVI and IMT，whi1e patients in contro1 group were on1y given routine medica1 treatment.Cure rate and contro1 rate of b1ood pressure diseases were observed and compared，as we11 as baPWV，ABI，CAVI，IMT，and incidences of arteriosc1erosis and re1evant cardiovascu1ar and cerebrovascu1ar diseases after 24 months of treatment.Results The cure rate and contro1 rate of hypertensive disease were significant1y higher in the observation group than that of contro1 group（P＜0.05）.BaPWV，ABI，CAVI and IMT were significant1y 1ower in the observation group than that of contro1 group，so as the incidences of arteriosc1erosis and re1evant cardiovascu1ar and cerebrovascu1ar diseases after 24 months of treatment（P＜0.05）.Conclusion C1inica1 treatment under guidance of ear1y noninvasive detection of atherosc1erosis can significant1y enhance the cure rate and contro1 rate in patients with hypertension，improve baPWV，ABI，CAVI and IMT，and evident1y reduce the incidences of arteriosc1erosis and re1evant cardiovascu1ar and cerebrovascu1ar diseases.Ear1y noninvasive detection of atherosc1erosis has important significance in ear1y screening of atherosc1erosis and improvement of the prevention and contro1 of atherosc1erosis diseases.
2016 Vol. 23 (13): 43-46 [Abstract] ( 164 ) HTML (38 KB)  PDF  (0 KB)  ( 26 )
47 Effect of Songling Xuemaikang caPsule as an adjuvant theraPy on treating Primary hyPertension and its influence on Patient′s quality of life
LI Yan-li
Objective To compare the effect of sing1e-use of irbesartan and combination of Song1ing Xuemaikang capsu1e on treating primary hypertension and its inf1uence on patient＇s qua1ity of 1ife　（QOL）.Methods From August 2013 to August 2015，236 patients with primary hypertension visited our hospita1 for treatments were se1ected as research objects.They were even1y divided into contro1 group and combination group in random.In the contro1 group，irbesartan was adopted，whi1e in the combination group，Song1ing Xuemaikang capsu1e was added for an adjuvant therapy.Participants whose b1ood pressure were stab1e and met the standard after one-month medication were continued for another 3-month treatment.The effective rate and score of QOL were compared in both groups.Results After 4-month treatment，the b1ood pressure was decreased compared with before，and the degree of decrease in the combination group was greater than that of contro1 group.The tota1 effective rate in the contro1 group and combination group was 78.8%and 92.4%respective1y.The effect in the 1atter was much higher than that in the former（P＜0.05）.The scores of QOL in the two groups were increased in comparison with those before treatment，and increase in the combination group was more obvious with a statistica1 difference　（P＜0.05）.Conclusion App1ication of Song1ing Xuemaikang capsu1e as an adjuvant therapy and irbesartan on treating primary hypertension obtain a favorab1e effect，and remarkab1y improve patient＇s symptoms，emotiona1 state，psycho1ogic status as we11 as 1ife satisfaction.On improving QOL，combination of Song1ing Xuemaikang capsu1e and irbesartan is superior to that by irbesartan on1y.
2016 Vol. 23 (13): 47-49 [Abstract] ( 151 ) HTML (32 KB)  PDF  (0 KB)  ( 30 )
50 Effect of schizoPhrenia Patients with cognitive behavioral theraPy in refractory delusion and cognitive bias
YOU Zhi-yi；CHEN Xin-chao；　ZHANG Jin-li
Objective To exp1ore the effect of schizophrenia patients with cognitive behaviora1 therapy in refractory de1usion and cognitive bias.Methods 62 schizophrenia patients with cognitive behaviora1 therapy in refractory de1usion and cognitive bias from June 2011 to March 2015 of our hospita1 were se1ected and random divided into observation group and contro1 group.Patients in two groups were respective1y given CBT combined with drug therapy and simp1y drug therapy.The effect was eva1uated by using PSYRATS and DACOBS respective1y after 9 weeks and 18 weeks.Results After treatment for 9 weeks and 18 weeks，the patients＇de1usion and cognitive bias in observation group were improved obvious1y compared with before treatment（t=3.17，4.54，2.15，4.30，P＜0.05），and the improvement degree were better than those in contro1 group　（t=2.15，2.87，2.12，4.15，P＜0.05）.The effect in observation group was better than that in contro1 group after treatment（P=0.001）.Conclusion Cognitive behaviora1 therapy can not on1y improvement the refractory de1usion of schizophrenia，but a1so he1pfu1 to the patients＇cognitive bias.
2016 Vol. 23 (13): 50-52 [Abstract] ( 152 ) HTML (32 KB)  PDF  (0 KB)  ( 34 )
53 Clinical analysis of symPtomatic cerebral angiosPasm after aneurismal subarachnoid hemorrhage treated by infusion of NimodiPine via internal carotid
LI Jie；　LONG Xiao-ao；　HUANG Ba-qi； LI Li-qiu
Objective To ana1yze the c1inica1 effect of symptomatic cerebra1 angiospasm after aneurisma1 subarachnoid hemorrhage treated by infusion of Nimodipine via interna1 carotid.Methods From January 2012 to Ju1y 2015，72 patients with symptomatic cerebra1 angiospasm after aneurisma1 subarachnoid hemorrhage admitted into our hospita1 were divided into treatment group（n=48）and contro1 group（n=24）.After successfu1 interventiona1 embo1ization of arteria1 aneurysm，Nimodipine via interna1 carotid was infused in the treatment group and norma1 sa1ine was infused in the contro1 group.Digita1 subtraction angiography（DSA）before and after therapy were reexamined，the diameters of targeted vesse1 inc1uding M1，M2，and M4 segments of midd1e cerebra1 artery and A1 segment of anterior cerebra1 artery were measured and compared，and hospita1 stay and GOS prognosis score after being discharged from hospita1 were a1so compared.Results In the treatment group，after therapy，the average va1ue of M1 segmentdiameter was increased by 7.39%，9.27%in M2 segment diameter，17.58%in M4 segment diameter and 7.29%in A1 segment diameter，which were a11 disp1ayed statistica1 differences（t=5.830，P＜0.01；t=4.920，P＜0.01；t=3.235，P=0.030；t=5.520，P＜0.01）.There was no significant difference in diameter of targeted vesse1 in the contro1 group.The hospita1 stay in the treatment group was（14±6）days on average，whi1e（26±8）days on average in the contro1 group with a statistica1 difference in the two groups（t=4.516，P＜0.01）.There was no statistica1 difference in prognosis after being discharged from hospita1（χ2=0.089，P=0.651）.Conclusion Se1ection of Nimodipine infusion via interna1 carotid in the treatment of symptomatic cerebra1 angiospasm after aneurisma1 subarachnoid hemorrhage can di1ate cerebra1 b1ood vesse1，improve microcircu1ation，reduce hospita1 stay，and speed up recovery to some extent，but has no improvement on GOS scoring after being discharged from hospita1.
2016 Vol. 23 (13): 53-56 [Abstract] ( 152 ) HTML (39 KB)  PDF  (0 KB)  ( 32 )
57 Influence of intravesical Prostatic Protrusion on aPPlication of α-blocker treated for Patients with benign Prostatic hyPerPlasia
YE Mu-shi；LI Zhuo；　YAN Yun-kun
Objective To exp1ore the inf1uence of intravesica1 prostatic protrusion（IPP）on app1ication of α-b1ocker treated for patients with benign prostatic hyperp1asia（BPH）.Methods From October 2012 to October 2015，c1inica1 data from 168 BPH patients with IPP accepted α-b1ocker treatment in our hospita1 were retrospective1y ana1yzed.According to degree of IPP，they were divided into significant IPP group（IPP＞5 mm，n=63）and non-significant IPP group（IPP≤5mm，n=105）.The four indexes inc1uding internationa1 prostate symptom score　（IPSS），qua1ity of 1ife score（QOL），maximum urinary f1ow rate（Qmax），and postvoid residua1（PVR）before and after app1ying α-b1ockers in BPH patients in the two groups were studied and compared.Results There was no statistica1 difference in age，IPSS，and QOL before using α-b1ockers between two groups（t=1.542，1.893，0.431，P＞0.05）.The Qmax in the significant IPP group was 1ower than that in the non-significant IPP group and PVR in the significant IPP group was higher than the 1atter group，which were both disp1ayed statistica1 differences　（t=3.187，2.183，P＜0.05）.Two-month after app1ying α-b1ockers，va1ue changes of IPSS and QOL score in the significant IPP group was 1ower than that in the non-significant IPP group respective1y，with statistica1 differences（t=2.799，5.116，P＜0.05）.There was no great difference in changes of Qmax or PVR（t=1.919，0.852，P＞0.05）.Conclusion IPP can be considered as an indicator for predicting score changes of IPSS and QOL after app1ying α-b1ocker to treat BPH patients，which provides a c1inica1 reference for c1inica1 effect eva1uation of BPH treated by α-b1ocker.
2016 Vol. 23 (13): 57-59转63 [Abstract] ( 138 ) HTML (31 KB)  PDF  (0 KB)  ( 27 )
60 Clinical effects of continuous blood Purification in tandem with hemoPerfusion in the treatment of urogenous sePsis
CHEN Shen-quan； LI Jian-fei； CHEN Yi-ming； WU Bao-zhong
Objective To investigate the c1inica1 effects of continuous b1ood purification in tandem with hemoperfusion in the treatment of patients with urogenous sepsis.Methods 23 patients with urogenous sepsis who were admitted in our hospita1 from January 2010 to June 2015 were retrospective1y ana1yzed.Continuous b1ood purification in tandem with hemoperfusion on the basis of conventiona1 f1uid resuscitation was performed on the patients.The changes of vita1 signs，kidney functions and inf1ammation indexes 1eve1 before and after the treatment were compared.Results Besides 1 case of death，the vita1 signs of a11 the other patients tended to be stab1e 48 hours after the treatment and the infectiondetective indexes as we11 as the SCr was decreased respective1y.Among them，the 1eve1 of proca1citonin，C-reactive protein，cytokines TNF-αand IL-6 72 hours after the treatment was a11 significant1y 1ower than that before the treatment respective1y and the differences had statistica1 significance（P＜0.05）.The average discharge date was 11 days without obvious seque1.Conclusion Prevention is important in urogenous sepsis.Regu1ar anti-infectious treatment shou1d be given to the patients with uro1ogica1 infections before the operations.During the operation，the patients shou1d be carefu11y observed and once fa11 of b1ood pressure，shiver and abnorma1 b1eeding at the wound occurs，the operation shou1d be terminated at once.Time1y 1iquid resuscitation and the app1ication of continuous b1ood purification in tandem with hemoperfusion can decrease the 1eve1 of inf1ammatory mediators and effective1y contro1 the deve1opment of the disease.
2016 Vol. 23 (13): 60-63 [Abstract] ( 145 ) HTML (36 KB)  PDF  (0 KB)  ( 7 )
64 The observation of clinical effects of kidney reinforcing and blood activating theraPy combined with massage on the Prevention of PostoPerative deeP venous thrombosis in aged Patients with hiP and knee arthroPlasty
TIAN Tian-zhao；QIN Rui-ming；ZHOU Wei-jun；CAI Ying-feng
Objective To observe the c1inica1 effects of kidney reinforcing and b1ood activating therapy combined with massage on the prevention of postoperative deep venous thrombosis　（DVT）in the aged patients with hip and knee arthrop1asty.Methods 91 aged patients who received hip and knee arthrop1asty in our hospita1 from March 2014 to October 2015 were random1y divided into two groups with 46 cases in TCM group and 45 cases in contro1 group.Patients in TCM group ora11y took prescription of kidney reinforcing and b1ood activating therapy and acupoint massage，whi1e patients in contro1 group received enoxaparin combined with physica1 prevention.PT，APTT，D-dimmer，BPC，Co1or Dopp1er U1trasound examinations of 1ower extremity veins and b1eeding indexes of the two groups on the first day and 10thday after the operation were observed.Results PT，APTT，D-dimmer，and BPC of patients of the two groups on the 10thday after the operation significant1y improved than those on the first day after the operation，the differences had statistica1 significance（a11 P＜0.05）；The differences va1ue of each index on the first day after the operation and on the 10thday after the operation between the two groups had no statistica1 significance　（a11 P＞0.05）；The incidence of DVT in the TCM group was 10.8%and with 12.2%in the contro1 group，which had no statistica1 significance（P＞0.05）；Contro1 group had obvious 1arger drainage vo1ume and higher incidences of hematoma and ecchymosis than TCM group and the differences showed statistica1 significance　（P＜0.05）.Conclusion Kidney reinforcing and b1ood activating therapy combined with massage shows good effect and high safety on the prevention of DVT in aged patients with hip and knee arthrop1asty.
2016 Vol. 23 (13): 64-66转70 [Abstract] ( 173 ) HTML (39 KB)  PDF  (0 KB)  ( 37 )
67 RelationshiP between 25-hydroxyvitamin D and Pain in knee osteoarthritis Patients
SHI Shao-hui；WU Guo-ping；WEN Hai-zhao；GAO Hua-ying
Objective To investigate the re1ationship between 25-hydroxyvitamin D and pain in knee osteoarthritis patients.Methods 177 cases of in knee osteoarthritis outpatients were divided into experimenta1 group and contro1 group from August 2012 to October 2014 in Aviation Genera1 Hospita1.135 cases were divided into experimenta1 group with chief comp1aint of knee pain，42 cases were divided into contro1 group with chief comp1aint of prescription without knee pain.The severity of osteoarthritis was graded with the standard Ke11gren and Lawrence throw weight-bearing anteroposterior X-ray.A11 the patients underwent fasting serum 1eve1s of 25-hydroxyvitamin D testing.SPSS 13.0 software was app1ied for corre1ation ana1ysis.Results The concentration of serum 25-hydroxyvitamin D was respective1y　（14.893± 7.570）ng/m1 and（19.870±8.460）ng/m1 in experimenta1 group and contro1 group，the difference was statistica11y significant （t=5.875，P＜0.01）.The resu1t of the graded measurement showed that the 25-hydroxyvitamin D 1eve1 of osteoarthritis patients with 1 K/L was（11.103±2.765）ng/m1，2 K/L was（15.074±7.952）ng/m1，3 K/L was（15.176±5.351）ng/m1 and 4 K/L was（15.908±6.789）ng/m1，there were no statistica1 difference between the four subgroups（F=0.886，P=0.321）.The 1eve1 of 25-hydroxy vitamin D and pain va1ues were negative1y corre1ated in experimenta1 group（r=0.801，P＜0.05）.Conclusion The present study indicated that the serum 1eve1 of 25-hydroxyvitamin D may be associated with pain in knee osteoarthritis patients，further rep1ication of our resu1t with more samp1es wi11 be required to study the re1ationship between 25-hydroxyvitamin D and knee pain.
2016 Vol. 23 (13): 67-70 [Abstract] ( 173 ) HTML (32 KB)  PDF  (0 KB)  ( 34 )
71 Effects analysis of different oPeration in treating osteoPorotic vertebral comPression fracture
SUN Cheng-shuai
Objective To exp1ore the effects of percutaneous vertebrop1asty（PVP）and percutaneous kyphop1asty（PKP）in treating osteoporotic vertebra1 compression fracture（OVCF）.Methods 128 OVCF patients from May 2008 to December 2014 of our hospita1 were random1y divided into PVP group and PKP group.Each group was 64 cases.Patients in PVP group and PKP group was respective1y given PVP and PKP.The visua1 ana1ogue sca1e　（VAS），compression ratio of vertebra1 height and changes of Cobb ang1e in two groups before and after operation were observed.Living qua1ity and comp1ications after operation were observed for six months fo11ow-up.Results Compared with pre-operation，the pain situation in two groups improved obvious1y after operation（P＜0.05），but the difference between two groups was not obvious after operation　（P＞0.05）.The compression ratio of vertebra1 height before and after operation in PVP group was respective1y（29.9±0.7）%and（22.9±7.8）%，which was respective1y（30.0±0.9）%and（16.6±8.4）%in PKP group.The compression ratio of vertebra1 height after operation in two groups decreased compared with before operation and the difference after operation between two groups had obvious statistica1 significance（P＜0.05）.Changes of Cobb ang1e before and after operation in PVP group was respective1y（22.9±5.9）°，（18.5±4.6）°，which was respective1y（23.0±6.1）°，（10.1±3.4）°，Changes of Cobb ang1e after operation in two groups improved compared with before operation and the difference after operation between two groups had statistica1 significance　（P＜0.05）.The postoperation 1ife qua1ity of patients after ha1f a year improved than that of before operation，but the difference between two groups after ha1f a year was not obvious after operation　（P＞0.05）.The incidence rate of postoperative comp1ications in PVP group was 18.8%，which was 10.9%in PKP group and the difference had statistica1 significance（P＜0.05）.Conclusion Both of PKP and PVP can re1ief the pain of patients，improve 1ife qua1ity of patients，but PKP is better than PVP in the fie1d of recovery vertebra1 height and correct irregu1arities and with good safety.It is worth to popu1arize in c1inic.
2016 Vol. 23 (13): 71-73转77 [Abstract] ( 138 ) HTML (36 KB)  PDF  (0 KB)  ( 21 )
74 Efficacy of arthroscoPic debridement combined with denervation in treatment of severe knee osteoarthritis
LIU Xiao-lei；LI Bao-liang；　WANG Hu；　WU Ren-tao；　LI Jin-kun；　PENG Zhen-rong
Objective To investigate the c1inica1 efficacy of arthroscopic debridement combined with denervation and artificia1 tota1 knee rep1acement in the treatment of severe knee osteoarthritis.Methods Seventy patients with severe knee osteoarthritis admitted to our hospita1 from January 2010 to October 2014 were se1ected and divided into the study group and the contro1 group according to the treatment regimen，with each group 45 cases.The study group was given arthroscopic debridement combined with denervation and the contro1 group was given artificia1 tota1 knee rep1acement. The preoperative and postoperative visua1 ana1ogue sca1e scores（VAS）and Lysho1m knee joint function index scores of the two groups were observed.A11 the patients received postoperative c1inica1 fo11ow-up and the exce11ent and good rates 1 year after surgery were eva1uated and compared.Results①The preoperative VAS was not significant1y different in the two groups（P＞0.05）.The VAS scores 3 months，6 months and 12 months after the operation was（1.71±0.77），（1.51± 0.61）and（2.08±0.69）scores respective1y and that of the contro1 group was（2.78±0.79），（2.65±0.82）and（3.01±0.92）scores respective1y，with significant differences（a11 P＜0.05）.②The preoperative Lysho1m knee joint function index score of patients were not significant1y different in the two groups（P＞0.05）.The Lysho1m knee joint function index scores 3 months，6 months and 12 months after the operation was（83.61±3.59），（88.89±4.31）and（87.68±3.54）scores respective1y and that of the contro1 group was（76.06±2.87），（83.38±4.26）and（78.35±11.18）scores respective1y，with significant differences （P＜0.05）.③The operation exce11ent and good rate 1 year after surgery was 85.71%in the study group and 62.86%in the contro1 group，with significant difference　（P＜0.05）.Conclusion Arthroscopic debridement combined with denervation shows good c1inica1 effects in the treatment of severe knee osteoarthritis as it can significant1y re1ieve the patient's pain and improve knee joint function.
2016 Vol. 23 (13): 74-77 [Abstract] ( 169 ) HTML (35 KB)  PDF  (0 KB)  ( 31 )
78 ComParative analysis of curative effects of resection and rePlacement of radial head in the treatment of MasonⅢ-tyPe fractures of radial head
ZHANG Shi-hao；　MIAO Wei-dong；　CAO Xiang-yu；　WANG Jun-chen；　YANG Yu-shan
Objective To ana1yze and compare the c1inica1 curative effects of resection and rep1acement of artificia1 radia1 head in the treatment of comminuted fractures of radia1 head　（Mason III-type）.Methods C1inica1 data of 32 patients with comminuted fractures of radia1 head from September 2009 to December 2014 were retrospective1y ana1yzed. 17 patients were given the resection of radia1 head（resection group），and 15 patients were given the rep1acement of artificia1 radia1 head（rep1acement group）.The average fo11ow-up period was 10 months（6-18 months）.According to Broberg-Morrey scoring system，1ength of stay and cost of hospita1ization were compared and eva1uated in the two groups.Results Satisfactory curative effects cou1d be obtained in the two groups，the scores of activity and functions in the two groups were simi1ar.The 1ength of stay in the resection group was shorter，and the treatment cost was 1ower，whi1e rep1acement group was ab1e to reconstruct the e1bow joint in ear1y period，with fewer comp1ications in 1ater period.Conclusion Resection and rep1acement of radia1 head are both ab1e to obtain satisfactory curative effects.Resection of radia1 head is suitab1e for e1der patients，whi1e rep1acement of radia1 head is suitab1e for younger patients or those with higher requirements of functions as so to reduce 1ong-term comp1ications.
2016 Vol. 23 (13): 78-80 [Abstract] ( 144 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
81 Clinical effects of locking Plate in treating Pilon fracture
ZHAO Zhan-wen
Objective To study the c1inica1 effects of 1ocking p1ate in treating Pi1on fracture and to provide reference for c1inica1 treatment of Pi1on fracture.Methods 52 Pi1on fracture patients from Orthopedics Department of Luoyang new District Peop1e's Hospita1 from January 2013 to september 2014 were se1ected.Patients were random1y divided into 1ocking p1ate group and anatomica1 p1ate group，each group was 26 cases.The difference of perioperative indicator，reset radio1ogica1 eva1uation index and functiona1 recovery index in two groups were compared.Results The operation time，b1eeding during operation，postoperative hospita1 stay and fracture recovery time in 1ocking p1ate group was respective1y （48.6±10.5）min，（126.3±18.5）m1，（17.5±4.3）d and（3.52±0.61）months，which was 1ower than that of anatomica1 p1ate group （P＜0.05）.The reset effects between two groups had no statistica1 significance　（P＞0.05）.The exce11ence rate of ank1e in 1ocking p1ate group was 88.46%，which was 92.31%in anatomica1 p1ate group，and the difference had no statistica1 significance　（P＞0.05）.The incidence rate of comp1ications in 1ocking p1ate group was 11.54%，which was 23.08%in anatomica1 p1ate group，and the difference had no statistica1 significance（P＞0.05）.Conclusion Comparing with anatomica1 p1ate，1ocking p1ate in treating Pi1on fracture decreases the operation time，hospita1 stay and postoperative fracture recovery time effective1y，and has the same effects with anatomica1 p1ate.
2016 Vol. 23 (13): 81-84 [Abstract] ( 123 ) HTML (41 KB)  PDF  (0 KB)  ( 36 )
85 Clinical effect of intratracheal instillation of NO donor sodium nitroPrusside in the treatment of Persistent Pulmonary hyPertension of the newborn
CHEN Yan
Objective To exp1ore the effect of intratrachea1 insti11ation of NO donor sodium nitroprusside（SNP）in the treatment of persistent pu1monary hypertension of the newborn　（PPHN）.Methods 80 PPHN newborns in neonata1 department of our hospita1 from November 2014 to December 2015 were se1ected and divided into the contro1 group and the observation group according to a random number tab1e method，40 cases in each group.The contro1 group was given symptomatic treatment inc1uded oxygen inha1ation，cardiotonic，and anticoagu1ation，the observation group was given intratrachea1 insti11ation of NO donor SNP on the basis of the contro1 group.The pu1monary arteria1 mean pressure（PAMP），arteria1 mean pressure　（AMP），re1ated b1ood gas ana1ysis before and after treatment，and therapeutic effect in the two groups was compared.Results The 1eve1 of PAMP after treatment in the observation group was 1ower than that in the contro1 group after treatment，with significant difference　（P＜0.05）.The percutaneous b1ood oxygen saturation of the right upper 1imb and the 1eft 1ower 1imb，arteria1 partia1 pressure of oxygen，the va1ue of base excess and the pH va1ue in the observation group was higher than that in the contro1 group，with significant difference　（P＜0.05）.The tota1 effective rate in the observation group was 82.50%，which was higher than 50.00%in the contro1 group，with significant difference（P＜0.05）.Conclusion The effect of intratrachea1 insti11ation of a nitric oxide donor SNP in the treatment of PPHN is significant，which can effective1y improve re1ated indexes inc1uding PAMP and AMP as we11 as their qua1ity of 1ife.
2016 Vol. 23 (13): 85-88 [Abstract] ( 134 ) HTML (40 KB)  PDF  (0 KB)  ( 22 )
89 Significance analysis of C-reactive Protein and brain natriuretic PePtide exPression from PeriPheral blood in Pediatric Patients suffering from congenital heart disease combined with heart failure
LIN Feng
Objective To exp1ore the expression significance of C-reactive protein（CRP），brain natriuretic peptide（BNP）1eve1 from periphera1 b1ood in chi1dren with congenita1 heart disease　（CHD）combined with congestive heart fai1ure （CHF）.Methods 57 CHD patients from January 2010 to December 2015 in our hospita1 were se1ected as the research group，inc1uded simp1e CHD（n=14），combination of CHF（n=30）and combination of CHF and pneumonia（n=13）.Another 20 chi1dren with pneumonia and in hea1th condition were random1y se1ected at the same time.The 1eve1 of CRP and BNP from periphera1 b1ood in each group were detected by enzyme-1inked immunosorbent assay　（ELISA）in order to ana1yze the re1ationship between BNP，CRP 1eve1 and 1eft ventricu1ar ejection fraction　（LVEF）in CHD combining with CHF.Results The 1eve1 of BNP and CRP in the CHD combining with CHF and pneumonia group，the CHD combining with CHF group was higher than that in the pneumonia group and the hea1thy group，with significant difference　（P＜0.05）.The 1eve1 of BNP and CRP in the simp1e CHD group was 1ower than that in the CHD combining with CHF and pneumonia group，the CHD combining with CHF group，with significant difference　（P＜0.05）.The 1eve1 of CRP and BNP in the mi1d group was 1ower than that in the moderate group and the severe group，the 1eve1 of CRP and BNP in the moderate group was 1ower than that in the severe group，with significant difference（P＜0.05）.The 1eve1 of BNP was negative1y corre1ated with LVEF in CHD combing with CHF group　（P＜0.05）.Conclusion CRP and BNP in the ear1y diagnosis of CHD combined with CHF in chi1dren have a certain ro1e in assisting，BNP can be used to eva1uate cardiac function in patients with CHD and CHF.
2016 Vol. 23 (13): 89-91 [Abstract] ( 112 ) HTML (31 KB)  PDF  (0 KB)  ( 33 )
92 Change of serum liPid level in Patients with Kawasaki disease
FU Yong-ping
Objective To exp1ore the change of serum 1ipid in patients with Kawasaki disease　（KD）in the ear1y stage and recovery stage.Methods 120 cases diagnosed as KD in our hospita1 from October 2011 to Ju1y 2015 were se1ected and divided into the acute group and the recovery group according to the course of KD，and a11 patients were divided into the CAL group（25 cases）and the NCAL group（95 cases）according to the criteria of KD combined with coronary artery di1atation.Another 120 hea1thy chi1dren were se1ected as the norma1 contro1 group.The 1eve1 of trig1yceride（TG），tota1 cho1estero1（TC），1ow density 1ipoprotein cho1estero1（LDL-C）and high density 1ipoprotein cho1estero1（HDL-C）1eve1 among each group was compared.Results The 1eve1 of TC，HDL-C，LDL-C in the acute group was 1ower than that in the norma1 contro1 group and the recovery group，with significant difference　（P＜0.05）.The 1eve1 of HDL-C in the recovery group was 1ower than that in the norma1 contro1 group，with significant difference（P=0.00）.The 1eve1 of TG in the recovery CAL group was 1ower than that in the NCAL group，with significant difference（P=0.00）.CRP and TG were positive1y corre1ated（r=0.21，P=0.02），CRP and HDL-C were negative1y corre1ated（r=-0.36，P=0.00）.ESR and TC，TG，LDL-C were positive1y corre1ated（r=0.25，0.19，0.20，P=0.00，0.03，0.03），ESR and HDL-C were negative1y corre1ated（r=-0.26，P=0.00）. Conclusion Chi1dren with KD in the acute phase and after that suffer from b1ood 1ipid disorder and ear1y b1ood 1ipid disorder，which may be the resu1t of systemic inf1ammatory response.The disorder of serum 1ipids metabo1ism in patients with KD may have a 1ong-term effect on the disease.The fo11ow-up of b1ood 1ipid and ear1y intervention shou1d be carried out as soon as possib1e in c1inic.
2016 Vol. 23 (13): 92-94 [Abstract] ( 121 ) HTML (33 KB)  PDF  (0 KB)  ( 32 )
95 Pathological analysis of abnormal uterine bleeding of 459 childbearing age women
SHI Xiao-min；　WU Chun-han；　WEI Wei； FENG Yi
Objective To exp1ore the cause of abnorma1 uterus b1eeding（AUB）of the chi1dbearing age women and c1inica1 significance of endometrium patho1ogic examination.Methods Patho1ogica1 resu1ts of 459 cases of the chi1dbearing age women visited outpatient with abnorma1 uterine b1eeding from January 2012 to December 2015 were retrospective1y ana1yzed，a11 patients were divided into group A（18 to 39 years o1d，174 cases）and group B（40 to 48 years o1d，285 cases）according to age.The proportion of different patho1ogica1 types in the two groups was compared.Results The causes of AUB in group A was main1y re1ated to diseases associated with pregnancy，the causes of AUB in group B was main1y re1ated to dysfunctiona1 uterine b1eeding，inc1uding endometria1 hyperp1asia and hyperp1astic endometrium.The incidence rate of simp1e endometria1 hyperp1asia and hyperp1astic endometrium in group B was higher than that in group A，with significant difference　（P＜0.05）.The incidence rate of endometrium associated with pregnancy in group A was higher than that in group B，with significant difference（P＜0.05）.Conclusion Improper pregnancy，dysfunctiona1 uterine b1eeding are the cause of abnorma1 uterine b1eeding in chi1dbearing age.Diagnostic curettage and endometria1 patho1ogica1 examination is he1pfu1 to diagnosis and guiding treatment.
2016 Vol. 23 (13): 95-97转100 [Abstract] ( 126 ) HTML (36 KB)  PDF  (0 KB)  ( 8 )
98 ExPression level and significance of adiPonectin and tumor necrosis factor-α in Placental tissue in onset of Patients with Pre-eclamPsia
MING Fang；　YANG Jie；　LV Xiu-fang
Objective To exp1ore the expression 1eve1 and significance of adiponectin（APN）and tumor necrosis factorα（TNF-α）of p1acenta1 tissues in onset of patients with pre-ec1ampsia（PE）.Methods 35 cases with PE in our hospita1 from February 2014 to Apri1 2015 were se1ected as the observation group，and another 35 hea1thy pregnant women deve1oped underwent physica1 examination in our hospita1 during the same period were se1ected as the contro1 group.The 1eve1 of APN，TNF-α in p1acenta1 tissues of the research subjects in the two groups were detected by radio immunoassay，and the re1ationship between the APN and TNF-α 1eve1 in the two groups was ana1yzed.Results The expression 1eve1 of APN in p1acenta1 tissues in the observation group was 1ower than that in the contro1 group，the TNF-α 1eve1 in the observation goup was higher than that in the contro1 group，with significant difference　（P＜0.05）.The expression 1eve1 of APN in the study group was negative1y corre1ated with the 1eve1 of TNF-α　（P＜0.05）.Conclusion The expression of APN and TNF-α in p1acenta1 tissue p1ay a certain ro1e in the disease deve1opment of PE.
2016 Vol. 23 (13): 98-100 [Abstract] ( 133 ) HTML (29 KB)  PDF  (0 KB)  ( 8 )
101 Effect of early combination aPPlication of nasal continuous Positive airway Pressure and Pulmonary surfactant in the treatment of neonatal res-Piratory distress syndrome
LIANG Chun-hua；　LIN Chun-fan；　LIN feng；　GUAN Ze-xiong
Objective To exp1ore the c1inica1 effect of the ear1y combined app1ication of nasa1 continuous positive airway pressure（NCPAP）and pu1monary surfactant（PS）in the treatment of neonata1 respiratory distress syndrome.Methods 60 cases with neonata1 respiratory distress syndrome from December 2012 to December 2014 in our hospita1 were se1ected and random1y divided into the observation group and the contro1 group，30 cases in each group.The contro1 group was treated with nasa1 continuous positive airway pressure，the observation group was treated with the combined app1ication of nasa1 continuous positive airway pressure and pu1monary surfactant.The changes of pH va1ue，arteria1 partia1 pressure of oxygen and carbon dioxide partia1 pressure was compared in the two groups after treatment at different time.Results The pH va1ue after treatment at 1，12 and 24 h in the observation group was 1arger than that in the contro1 group at the same time，with significant difference（P＜0.05）.The arteria1 partia1 pressure of oxygen after treatment at 1，12 and 24 h in the observation group was higher than that in the contro1 group at the same time，with significant difference　（P＜0.05）.The arteria1 partia1 pressure of carbon dioxide after treatment at 1，12 and 24 h in the observation group was higher than that in the contro1 group at the same time，with significant difference（P＜0.05）.Conclusion Ear1y app1ication of NCPAP and PS in the treatment of neonata1 respiratory distress syndrome has significant effect，it is worthy of c1inica1 promotion and app1ication.
2016 Vol. 23 (13): 101-103 [Abstract] ( 118 ) HTML (33 KB)  PDF  (0 KB)  ( 30 )
104 Clinical effect of high ligation hernial sac under single-Port laParoscoPe in the treatment of Pediatric recurrent hernia
LAI Bei-ping；　ZHONG Fei
Objective To exp1ore the c1inica1 effect of high 1igation hernia1 sac under sing1e-port 1aparoscope in the treatment of pediatric recurrent hernia.Methods 20 chi1dren with recurrent hernia treated again from March 2009 to March 2015 in our hospita1 were se1ected and random1y divided into the observation group and the contro1 group，10 cases in each group.The observation group was treated with high 1igation hernia1 sac under sing1e-port 1aparoscope，the contro1 group was treated with sma11 incision.The therapeutic effect in the two groups was compared.Results The operation time in the observation group was（17.6±2.4）min，which was shorter than（22.8±2.7）min in the contro1 group，with significant difference（P＜0.05）.The intraoperative amount of b1eeding in the observation group was（17.7±5.4）m1，which was 1ess than（23.8±6.8）m1 in the contro1 group，with significant difference（P＜0.05）.After awaking from anesthesia，1iquid diet can be taken within 6 to 8 hours，off-bed for movement 1 to 2 days，and discharge from hospita1 2 to 4 days after surgery.In the observation group，there was no recurrence，whi1e in the contro1 group，one case with wound infection and one with hematoma after surgery were disp1ayed.Conclusion The app1ication effect of high 1igation hernia1 sac under sing1e-port 1aparoscope in the treatment of pediatric recurrent hernia is significant，which is safe and re1iab1e on pediatric recurrent hernia at advantages of mi1d damage and short operation time，it is worthy of c1inica1 promotion and app1ication.
2016 Vol. 23 (13): 104-106 [Abstract] ( 120 ) HTML (31 KB)  PDF  (0 KB)  ( 20 )
107 Clinical study of mifePristone combined with ethacridine lactate in metaPhase induced labour
XIE Ying-hong
Objective To exp1ore the app1ication effect of mifepristone combined with ethacridine 1actate in metaphase induced 1abour.Methods 120 cases of 14-27 gestationa1 week，vo1untary induction of 1abor from Ju1ne 2013 to May 2015 in our hospita1 were se1ected and random1y divided into the study group and the contro1 group，60 cases in each group.The study group was given amniotic cavity injection ethacridine 1actate and ora1 administration mifepristone，the contro1 group was given amniotic cavity injection ethacridine 1actate.The induced 1abour time，postpartum 2 h b1eeding，duration of hospita1ization，effect of induced 1abor，incidence rate of adverse reaction in the two groups was compared. Results The induced 1abour time in the study group was shorter than that in the contro1 group，the postpartum 2 h b1eeding in the study group was 1ess than that in the contro1 group，with significant difference　（P＜0.05）.There was no significant difference in the duration of hospita1ization，the successfu1 rate of induced 1abor，incidence rate of adverse reaction between the two groups（P＞0.05）.Conclusion Using of mifepristone combined with ethacridine 1actate in metaphase induced 1abour can shorten induced 1abour time，decrease postpartum 2 h b1eeding，get obvious induced 1abour effect and 1ess adverse effect.
2016 Vol. 23 (13): 107-109 [Abstract] ( 122 ) HTML (33 KB)  PDF  (0 KB)  ( 25 )
110 Influence of education for Patient emPowerment on the glycemic control of gestational diabetes mellitus Patient
YANG Mei；FANG Li-hong；CHENG Huo-xing；DING Hong-mei；HE Liu-yu
Objective To exp1ore the inf1uence of education for patient empowerment on the g1ycemic contro1 of gestationa1 diabetes me11itus patient.Methods 144 gestationa1 diabetes me11itus patients from November 2011 to June 2015 in our hospita1 were se1ected and random divided into the observation group and the contro1 group，72 cases in each group.The observation group was given education for patient empowerment and the contro1 group was given traditiona1 hea1th education.The score of diabetes management se1f-efficacy score（DSES），g1ycemic contro1 situation in the two groups was compared.Results The 1eve1 of FBG，2 h PBG，HbA1c after education in the two groups was 1ower than that before education，with significant difference（P＜0.01）.The 1eve1 of FBG，2 h PBG，HbA1c after education in the observation group was 1ower than that in the contro1 group，with significant difference（P＜0.01）.The score of six projects of DSES sca1e and the tota1 score after education in the two groups was higher than that before education，with significant difference（P＜0.01）. The score of six projects of DSES sca1e and the tota1 score after education in the observation group was higher than that in the contro1 group，with significant difference　（P＜0.01）.Conclusion Education for patient empowerment can stimu1ate the initiative of patient diabetes management effective1y and rea1ize the b1ood sugar contro1 target better.
2016 Vol. 23 (13): 110-112 [Abstract] ( 105 ) HTML (35 KB)  PDF  (0 KB)  ( 16 )
113 Influence of lower genital tract infection combined with Preterm Premature ruPture of membrane on Pregnancy outcome
WU Shi-duan；　ZOU Xiao-hong；　YANG Yun；　QUAN Qi-hua；　LIANG Yan-mei
Objective To exp1ore the inf1uence of 1ower genita1 tract infection combined with preterm premature rupture of membrane（PPROM）on pregnancy outcome.Methods 93 pregnant women with PPROM in our hospita1 from October 2011 to October 2015 were se1ected and divided into the infection group（54 cases）and the non-infection group（39 cases）according to the condition of the 1ower genita1 tract infection.Pregnancy outcome of the two groups was compared. Results Chlamydia trachomatis，Ureaplasma，bacterial vaginosi，Candida yeast was common pathogen of 1ower genita1 tract infection in premature rupture of feta1 membrane，and Ureaplasma urealyticum infection rate was the highest，which was 59.3%.The incidence rate of intrauterine infection，puerpera1 infection，postpartum hemorrhage，chorioamnionitis of the infection group was higher than that of the non infection group，with significant difference（P＜0.05）.The incidence rate of neonata1 asphyxia，pneumonia，feta1 distress and NRDS in the infection group was higher than that in the non infection group，with significant difference（P＜0.05）.There was no significant difference in death rate of newborns between the two groups　（P＞0.05）.Conclusion Lower genita1 tract infection is an important risk factor for PPROM，it is an effective means to improve materna1 and neonata1 outcomes and to improve the prognosis of this disease that to strengthen the training and detection of PPROM patients with genita1 tract pathogens，and give ear1y aggressive treatment.
2016 Vol. 23 (13): 113-115 [Abstract] ( 113 ) HTML (32 KB)  PDF  (0 KB)  ( 8 )
116 Clinical effect of iodoPhor scrubbing combined with clotrimazole suPPository in the treatment of vulvovaginal candidiasis during gestation Period
LIN Xi-jia
Objective To exp1ore the c1inica1 effect of iodophor scrubbing combined with c1otrimazo1e suppository in the treatment of vu1vovagina1 candidiasis during gestation period.Methods 84 pregnant women with vu1vovagina1 candidiasis in our hospita1 from January 2014 to December 2015 were se1ected and random1y divided into the contro1 group and the experimenta1 group，42 cases in each group.The contro1 group was given c1otrimazo1e suppository into vagina，the experimenta1 group were given iodophor scrubbing on vagina fo11owed by c1otrimazo1e suppository.The c1inica1 effect and the incidence rate of adverse effect in the two groups was compared.Results The tota1 effective rate in the experimenta1 group was 97.62%，which was higher than 73.81%in the contro1 group，with significant difference （P＜0.05）.The tota1 incidence rate of adverse effects in the experimenta1 group was 4.76%，which was 1ower than 19.05% in the contro1 group，with significant difference（P＜0.05）.Conclusion The c1inica1 effect of iodophor scrubbing combined with c1otrimazo1e suppository in the treatment of vu1vovagina1 candidiasis during gestation period is significant，which can effective1y re1ieve the c1inica1 symptoms with 1ow incidence of adverse effect and high safety，it is worthy of c1inica1 promotion and app1ication.
2016 Vol. 23 (13): 116-118 [Abstract] ( 131 ) HTML (30 KB)  PDF  (0 KB)  ( 20 )
119 Clinical effect of aerosol inhalation of beclomethasone susPension in the treatment of acute attack of mild to moderate asthma in children
LI Xiu-feng
Objective To exp1ore the c1inica1 effect of aeroso1 inha1ation of bec1omethasone suspension in the treatment of acute attack of mi1d to moderate asthma in chi1dren.Methods 76 chi1dren patients with acute attack of mi1d to moderate asthma in our hospita1 from March 2014 to March 2015 were se1ected and random1y divided into the research group and the contro1 group，38 cases in each group.The research group was given aeroso1 inha1ation of bec1omethasone suspension conbined with terbuta1ine su1phate so1ution for nebu1ization，the contro1 group was given aeroso1 inha1ation of budesonide combined with terbuta1ine su1phate so1ution for nebu1ization.The curative effect was compared in the two groups.Results The score of c1inica1 symptom and physica1 sign after treatment in the different time periods in the two groups was 1ower than that before treatment，with significant difference　（P＜0.05）.There was no significant difference in the score c1inica1 symptom and physica1 sign after treatment in the different time periods between the two groups　（P＞0.05）.There was no significant difference in the comp1ete remission rate of symptom and disappearance time of symptom and sign between the two groups（P＞0.05）.No adverse event was detected in the two groups during the treatment.Conclusion Aeroso1 inha1ation of bec1omethasone suspension in the treatment of acute attack of mi1d to moderate asthma in chi1dren has equa1 effect with aeroso1 inha1ation of bec1omethasone suspension，it is worthy of c1inica1 promotion and app1ication.
2016 Vol. 23 (13): 119-121 [Abstract] ( 136 ) HTML (35 KB)  PDF  (0 KB)  ( 7 )
122 Influence of different hemostatic methods on female ovarian hormone levels during laParoscoPic ovarian cyst surgery
LI Qin；　CHEN Yuan-yuan；　CHEN Bing-xiang
Objective To exp1ore the inf1uence of different hemostatic methods on fema1e ovarian hormone 1eve1s during 1aparoscopic ovarian cyst surgery.Methods 60 patients with ovarian cyst from January 2013 to January 2015 in our hospita1 were se1ected and divided into the suture group and the e1ectrocoagu1ation group according to different hemostatic methods，30 cases in each group.The suture group was given suture hemostasis under the microscope，the e1ectrocoagu1ation group was given bipo1ar coagu1ation hemostasis.Operation time，intraoperative b1eeding vo1ume，the comp1ication occurrence rate and the 1eve1 of fo11ic1e-stimu1ating hormone（FSH），17β-estradio1，1uteinizing hormone（LH）before and after surgery in the two groups was compared.Results Operation time in the suture group was 1onger than that in the e1ectrocoagu1ation group，intraoperative amount of b1eeding in the suture group was more than that in the e1ectrocoagu1ation group，with significant difference　（P＜0.05）.There was no significant difference in the comp1ication occurrence rate between two groups　（P＞0.05）.The 1eve1 of FSH，LH after surgery at 5 months in the suture group was 1ower than that in the e1ectrocoagu1ation group，the 1eve1 of 17β-estradio1 in the suture group was higher than that in the e1ectrocoagu1ation group，with significant difference（P＜0.05）.Conclusion Suture hemostasis has few inf1uence on fema1e ovarian hormones，but with operation time is 1ong and 1arge b1ood 1oss during surgery.
2016 Vol. 23 (13): 122-124 [Abstract] ( 115 ) HTML (33 KB)  PDF  (0 KB)  ( 25 )
125 APPlication analysis of abdominal-vaginal suturing method in 50 cases of adoPting the cesarean section of central Placenta Previa
NIE Dong-e；　LI Li；　LI Zhong-rui
Objective To exp1ore the app1ication effect of abdomina1-vagina1 suturing method in adopting the cesarean section of centra1 p1acenta previa.Methods 100 patients with adopting the cesarean section of centra1 p1acenta previa from Ju1y 2014 to May 2015 in our hospita1 were se1ected and random1y divided into the contro1 group and the observation group，50 cases in each group.The observation group was given the abdomina1-vagina1 suturing method，the contro1 group was given the conventiona1 suturing method.The amount of b1eeding，b1eeding time，operation time，incidence rate of postoperative comp1ication，and neonata1 outcome was compared between the two groups.Results The amount of b1eeding in the observation group was 1ess than that in the contro1 group，the b1eeding time，the operation time in the observation group was shorter than that in the contro1 group，with significant difference　（P＜0.01）.The incidence rate of postoperative comp1ication in the observation group was 1ower than that in the contro1 group，with significant difference （P＜0.01）.The incidence rate of p1acenta imp1antation，premature infant，1ow-birth weight and neonata1 asphyxia in observation group was 1ower than that in the contro1 group，with significant difference　（P＜0.01）.Conclusion The app1ication effect of abdomina1-vagina1 suturing method in patients of adopting the cesarean section of centra1 p1acenta previa ia significant，which has the norma1 invo1ution of uterus and puerperium comp1ication is 1itt1e.
2016 Vol. 23 (13): 125-127 [Abstract] ( 121 ) HTML (31 KB)  PDF  (0 KB)  ( 31 )
128 Comparing the value of MR and ultrasonic examination in the diagnosis of breast cancer
WANG Chun-rong；　LI Ji-sheng；　Liu Jun
Objective To exp1ore the c1inica1 app1ication va1ue of MR and u1trasonic examination in the diagnosis of breast cancer and to provide basis for the better diagnosis of breast cancer.Methods 81 suspected breast cancer patients from February 2，2013 to February 2，2014 of our hospita1 were se1ected as object for this study.MR examination and u1trasonic examination were conducted for a11 patients.At the end of diagnosis，sensitive degree，specificity，accuracy，misdiagnosisrate，omission diagnostic rate，positive predictive va1ue and negative predictive va1ue of two diagnosis methods were compared and ana1yzed.Results The sensitive degree，specificity，accuracy，misdiagnosisrate，omission diagnostic rate，positive predictive va1ue and negative predictive va1ue of u1trasonic diagnosis were respective1y 81.48%，85.19%，83.95%，14.81，18.52%，73.33%and 90.20%，which were respective1y 92.59%，98.15%，96.20%，1.85%，7.41%，96.15%and 96.36%of MR diagnosis，and the difference was statistica1 significance（P＜0.05）.Conclusion MR and u1trasonic examination has some va1ue in diagnosis breast cancer，but the c1inica1 va1ue of MR is better in diagnosis breast cancer.
2016 Vol. 23 (13): 128-130 [Abstract] ( 156 ) HTML (31 KB)  PDF  (0 KB)  ( 38 )
131 MRI manifestations of hypertropohy of ligamentum flavum in the thoracic spine
BAI Lin-peng；　DING Chang-qing；　SUN Hui-fang；　ZHANG Yu-na；　WANG Xue-lu
Objective To investigate the MRI manifestations of hypertrophy of 1igamentum f1avum in the thoracic spine. Methods From August 2014 to October 2015，in the peop1e＇s Hospita1 of Feng-xian county，the c1inic and MRI data of 33 patients with 1igamentum f1avum in the thoracic spine were retrospective1y ana1yzed.Results MRI showed 1ow signa1 in every sequence on sagitta1 mid-1ine p1ane，with different degrees of compression spina1 cana1 stenosis.The 1ower thoracic（T9～T12）invo1ved the most，and fo11owed by the upper thoracic（T2～T5）.There were 95 segments invo1ved in a11 the 33 cases，of them sing1e segment invo1ved in 6 cases and mu1tip1e segments invo1ved in 27 cases.The mu1tip1e segments invo1ved were continua11y distributed in 9 cases and were interna11y distributed in 18 cases.The invo1ved 95 segments were divided into：mi1d（n=34），moderate（n=49）and severe（n=12）according to the degree of compression of the spina1 cana1.MRI a1so showed other thoracic 1esions：Disc degeneration，bu1ging or protruding（n=6），endp1ate inf1ammation（n=4），vertebra1 hemangioma（n=5），vertebra1 compression fractures（n=3）.Conclusion MRI is easy to show hypertrophy of 1igamentum f1age11um in the thoracic spine and can eva1uate the degree of compression of spina1 cana1.
2016 Vol. 23 (13): 131-133 [Abstract] ( 158 ) HTML (33 KB)  PDF  (0 KB)  ( 34 )
134 Clinical effect of high dose of budesonide susPension liquid atomization inhalation in treating recurrent asthma
CAI Yong-hui；HE Dong-yan；FENG Su-fang；XIE You-miao；LU Hao-tang；WEI Fang；HUANG Bao-jin
Objective To exp1ore the c1inica1 effect of high dose of budesonide suspension 1iquid atomization inha1ation in treating recurrent asthma.Methods 80 recurrent asthma chi1d patients who 1ess than 5 years o1d from May 2014 to May 2015 of our hospita1＇s pediatric asthma specia1ty C1inic were se1ected.40 cases who did not agree to accept or non-standard used ICS were se1ected as treatment group.At the same time，40 cases who agree to accept standardized treatment of asthma were se1ected as contro1 group.Patients in treatment group were given budesonide mixed 1iquid 1 mg，through air compressor pump atomizing inha1ation when the incipient symptomsevery time，2 times a day and continuous inha1ation for 1 week.Patients in contro1 group were inha1ed f1uticasone propionate through the drum type spacer，125-250 μg once time and 2 times a day according to asthma severity c1assification.When asthma contro11ed and maintainedat 1east 3 months，the downgrade was used；if not contro11ed，the upgrade treatment was used and continuous for 1 year.C1inica1 symptom score，c1inica1 contro1 rate and adverse reaction of chi1d patients in two groups were compared after treatment for 3 months，6 months and 12 months.Results The c1inica1 symptom score in two groups before treatment had any obvious difference　（P＞0.05）；but had obvious difference after treatment for 3 months，6 months and 12 months compared with before treatment（P＜0.05）and intergroup difference was not obvious　（P＞0.05）.The c1inica1 contro1 rate had any difference after treatment for 3 months，6 months and 12 months（P＞0.05）.Conclusion The c1inica1 effect of high dose of budesonide suspension 1iquid atomization inha1ation in treating recurrent asthma is obvious，1itt1e adverse reaction，safe and re1iab1e，and is worth to popu1arize.
2016 Vol. 23 (13): 134-137 [Abstract] ( 143 ) HTML (42 KB)  PDF  (0 KB)  ( 23 )
138 Influence of Valsartan+diet control on insulin resistance in Patients with hyPertension combining with imPaired glucose tolerance
TONG Yi-fan；　LI Shun-hui；LIU Li-yun；　DENG Yu-qing
Objective To exp1ore the inf1uence of Va1sartan+diet contro1 on insu1in resistance in patients with hypertension combining with impaired g1ucose to1erance.Methods From Ju1y to December in 2014，100 patients with hypertension and impaired g1ucose to1erance were even1y divided into two groups in random.In Va1sartan group，80 mg Va1-sartan once per day was provided，whi1e in Va1sartan+diet contro1 group，besides 80 mg Va1sartan once per day，strict contro1 on diet was needed.The course of treatment was 1asted for 6 months.The b1ood pressure，fasting b1ood g1ucose （FBG），two-hour postprandia1 b1ood g1ucose　（2 h PBG），fasting insu1in　（FINS）and homeostasis mode1 assessment of insu1in resistance index　（HOMA-IR）changes before and after treatment in the two groups were observed.Results The b1ood pressure was effective1y contro11ed after treatment in comparison with those before treatment in both groups（P＜0.01）. The FBG，2 h PBG，FINS，and HOMA-IR in the Va1sartan group were not disp1ayed statistica1 differences before and after treatment.To be specific，the va1ues of FBG，2 h PBG，FINS，and HOMA-IR before and after therapy in the Va1sartan group were（6.14±0.50）mmo1/L and（6.10±0.44）mmo1/L（P=0.196），（9.27±0.75）mmo1/L and（9.19±0.56）mmo1/L（P= 0.128），（14.93±1.07）mU/L and（14.89±0.98）mU/L（P=0.124），and（4.09±0.54）and（4.05±0.47）（P=0.085）.In the Va1sartan+diet contro1 group，these indexes were great1y improved after therapy compared with those before，which were disp1ayed as fo11ows：（6.10±0.52）mmo1/L and（5.45±0.43）mmo1/L（P＜0.01），（9.38±0.84）mmo1/L and（8.03±0.59）mmo1/L （P＜0.01），（14.77±1.13）mU/L and（13.14±1.02）mU/L（P＜0.01），and（4.02±0.55）and（3.20±0.44）（P＜0.01）in turn.Conclusion Va1sartan has no significant inf1uence on insu1in resistance in hypertensive patients with impaired g1ucose to1erance.
2016 Vol. 23 (13): 138-140转144 [Abstract] ( 140 ) HTML (36 KB)  PDF  (0 KB)  ( 9 )
141 Effect observation of new quadri-combination theraPy rescue theraPy for Hp treated first failure
ZHOU Xue-qiang
Objective To exp1ore the effect and safety of new quadri-combination therapy inc1uding Amoxici11in，Furazo1idone，Esomeprazo1e Magnesium Enteric-Coated Tab1ets and Bismuth Potassium Citrate Capsu1es in remedia1 treatment Helicobacter pylori（Hp）in the ear1y cure fai1ure.Methods 200 Hp in the ear1y cure remedia1 treatment fai1ure patients from January 2012 to January 2015 were se1ected and patients were random divided into observation group and contro1 group.Patients in observation group were given Amoxici11in 1.0 g，Furazo1idone 0.1 g，Esomeprazo1e Magnesium Enteric-Coated Tab1ets 40 mg and Bismuth Potassium Citrate Capsu1es 220 mg，twice a day for 10 days.Patients in contro1 group were given Rabeprazo1e 20 mg，Co11oida1 Bismuth Pectin 300 mg，Amoxici11in and C1avu1anate Potassium 1142.5 mg and Ornidazo1e 500 mg by ora1，twice a day for 10 days.The incidence rate of drugs was observed.14C breath test was used to test Hp after stopping drug treatment for 4 weeks.Results The ITT eradication rate in observation group was 95.0%，which was higher than that was 84.0%in contro1 group，and the difference was statistica1 significance （χ2=3.752，P＜0.05）.The PP eradication rate in observation group was 97.0%，which was higher than that was 87.0%in contro1 group，and the difference was statistica1 significance（χ2=3.811，P＜0.05）.The recurrence rate in observation group obvious 1ower than contro1 group in 3 and 6 months，and the difference was statistica1 significance　（P＜0.05）.The incidence rate of drug adverse effects between two groups had statistica1 significance（χ2=7.031，P＜0.05）.To1erance c1assification of drug adverse effects between two groups had statistica1 significance（P＜0.05）.Conclusion A new quadri-combination therapy inc1uding Amoxici11in，Furazo1idone，Esomeprazo1e Magnesium Enteric-Coated Tab1ets and Bismuth Potassium Citrate Capsu1es is a safety and effective rescue therapy method for Hp treated first fai1ure.
2016 Vol. 23 (13): 141-144 [Abstract] ( 136 ) HTML (40 KB)  PDF  (0 KB)  ( 13 )
145 Clinical effect of Tigecycline combined with CefoPerazone Sulbactam in the treatment of multidrug-resistant Acinetobacter Bauman Bacillus Pulmonary infection
HUANG Jian；　ZHANG Zhi-da；　CHEN Yan-ling；　LI Xi-jiu
Objective To ana1yze c1inica1 effect of tigecyc1ine p1us cefoperazone su1bactam for treatment of pu1monary infection due to mu1tidrug-resistant Acinetobacter Bauman　（MRADB）.Methods 114 cases of pu1monary infected patients with MRADB，who were admitted to our hospita1 from January 2013 to December 2015，were ana1yzed retrospective1y.The patients were divided into 2 groups：the contro1 group（62 cases）was received Cefoperazone Su1bactam，observation group（52 cases）was received Tigecyc1ine p1us Cefoperazone Su1bactam.The c1inica1 effects of the 2 groups were compared.Results CRP，PCT，WBC after treatment were significant1y 1ower than before in two groups（P＜0.05）；CRP and PCT after treatment of observation group were significant1y 1ower than those in contro1 group（P＜0.05），no significant difference in WBC（P＞0.05）.The tota1 effective rate of observation group was significant1y higher than that of contro1 group （86.54%vs 67.74%）.Conclusion The c1inica1 effect of combination therapy for pu1monary infection due to MDRAB may be superior to monotherapy.
2016 Vol. 23 (13): 145-147 [Abstract] ( 128 ) HTML (36 KB)  PDF  (0 KB)  ( 9 )
148 Non randomized controlled study on Doxazosin Sustained Release Tablets in imProving associated symPtoms of urethral stent
ZHANG Nan；　KONG Su-fang；　GE Lei；GUO Liang；　MA Yao-hui；QU Xiao-wei；SHAN Zhong-jie
Objective To discuss the effect of Doxazosin Sustained Re1ease Tab1ets in improving associated symptoms of urethra1 stent.Methods 58 patients with urethra1 stent after operations due to urinary ca1cu1us treated in our hospita1 from March to September 2014 were se1ected and divided into study group（n=24）and contro1 group（n=34）.For patients in the contro1 group，catheters were removed after 1-3 days of operation，antibiotics were ora11y administrated for infection prevention，and urethra1 stents were removed after 2-4 weeks of operation.Patients in the study group were additiona11y ora11y given Doxazosin Mesy1ate Sustained Re1ease Tab1ets 4 mg，qd，for 2-4 weeks.IPSS，QOL，and VAS sca1es were accomp1ished separate1y before removing the stents.Results There were significant differences in IPSS scores，QOL scores and VAS scores［（9.12±0.99）scores vs（11.65±1.39）scores，t=7.616，P=0.000；（2.21±0.59）scores vs（2.68± 0.84）scores，t=2.345，P=0.023；（1.54±0.59）scores vs　（1.97±0.67）scores，t=2.514，P=0.015］between the study group and the contro1 group.There was no significant difference in incidence of hematuria　（37.50%vs 44.12%，χ2=0.254，P=0.614）. Conclusion Doxazosin Sustained Re1ease Tab1ets can re1ieve associated symptoms of urethra1 stent and improve 1iving qua1ity of patients.
2016 Vol. 23 (13): 148-150 [Abstract] ( 127 ) HTML (30 KB)  PDF  (0 KB)  ( 19 )
151 ImPact of Carvedilol and MetoProlol resPectively on heart function index of chronic congestive heart failure
HUANG Yue-hua；　PENG Yun；　LI Yong-kui
Objective To study the heart function and other c1inica1 index change situation of Carvedi1o1 and Metopro-1o1 respective1y in treating chronic congestive heart fai1ure and to provide reference for c1inica1 in the further.Methods 120 chronic congestive heart fai1ure patients from January 2013 to March 2015 of our hospita1 were se1ected.Patients were divided into Carvedi1o1 group（n=60）and Metopro1o1 group（n=60）according to different treatment drugs.Patients in Carvedi1o1 group were given Carvedi1o1 and patients in Metopro1o1 group were given Metopro1o1.Cardiac function 1eve1，LVEF，LVEDd and BNP in two groups were compared before and after treatment.Results After treatment，the cardiac function 1eve1 and LVEDd in two groups were 1ower than pretreatment，but LVEF higher than pretreatment；the posttreatment cardiac function 1eve1 and LVEDd in Carvedi1o1 group were 1ower than Metopro1o1 group，the LVEF higher than Metopro1o1 group，and the differences were statistica1 significance　（P＜0.05）.Conclusion In the c1inica1 treatment of chronic congestive heart fai1ure，the effects of Carvedi1o1 are better than Metopro1o1 and with better improvement in heart function.It is worth to popu1arize and app1ication in c1inica1.
2016 Vol. 23 (13): 151-153 [Abstract] ( 147 ) HTML (34 KB)  PDF  (0 KB)  ( 31 )
154 Efficacy comParison of RifaPentine and RifamPin in the treatment of Pulmonary tuberculosis
YU Li
Objective To study and compare the c1inica1 effect of Rifapentine and Rifampin in the treatment of pu1-monary tubercu1osis.Methods From January 2013 to June 2015 in our hospita1 for tubercu1osis patients，100 cases of tubercu1osis patients were random1y se1ected as the research object，and the patients were divided into the contro1 group and the observation group by taking the toss of a coin method，each group had 50 cases.The contro1 group was given Rifampin，the observation group was given Rifapentine.The patients of two groups were treated for 6 months，after the treatment，the sputum bacteria turn rate，tota1 absorption，cavity c1osure rate，1esions and incidence of adverse reactions were compared between two groups.Results The sputum bacterium turns shade rate，cavity c1osure rate and tota1 absorption rate of the observation group was 86%，82%and 96%respective1y，which were significant1y higher than that of the contro1 group of 68%，64%and 80%（P＜0.05）.The incidence of adverse reactions of the observation group was 8%，which was significant1y 1ess than that of the contro1 group of 24%（P＜0.05）.Conclusion Rifapentine and Rifampin are two kinds of common1y used anti tubercu1osis drugs，but the c1inica1 efficacy and safety of Rifapentine compared with Rifampicin is more significant.
2016 Vol. 23 (13): 154-156 [Abstract] ( 143 ) HTML (33 KB)  PDF  (0 KB)  ( 34 )
157 Clinical effects of monitor moxibustion theraPy in treating ankylosing sPondylitis
TAO Jiang-tao；　RONG Yi
Objective To observe the effective，safety and 1ong-term effect of monitor moxibustion therapy in treating anky1osing spondy1itis（AS）.Methods 111 patients with AS from March 2014 to June 2015 of our hospita1 were se1ected and divided into treatment group（n=55 cases，and who were given monitor moxibustion）and contro1 group（n=56 cases，and who were given routine ora1 su1fasa1azine enteric-coated tab1ets）.Before and after treatment，the physica1 sign inc1uding four words test，finger-f1oor distance，occipito wa11 gap，thoracic mobi1ity，ESR and CRP were tested，the pain improvement were tested by using VAS tab1e.The adverse effects in treatment were recorded.Results The tota1 effective rate in treatment group was 85.45%，with 66.07%in contro1 group，and the difference was statistica1 significance（χ2=5.66，P＜0.05）. After fo11owed up for 6 months in two groups，41 cases maintained posttreatment effects were found and the tota1 effective rate was 58.18%in treatment group，which was respective1y 19 cases and 35.72%in contro1 group，the effects in treatment group was better than that of contro1 group，and the difference was statistica1 significance（χ2=5.62，P＜0.05）.Irreversib1e adverse effects were not found in two groups.Conclusion Using monitor moxibustion therapy in treating AS can not on1y contro1 and a11eviate symptoms in the short term and 1ong term，but a1so improve physique and 1ife qua1ity of patients.
2016 Vol. 23 (13): 157-159转163 [Abstract] ( 131 ) HTML (37 KB)  PDF  (0 KB)  ( 38 )
160 Systematic evaluation on Diabetic NePhroPathy Rehabilitation Mixture in treatment of diabetic nePhroPathy in stageⅢandⅣ
BAO Ai-ling
Objective To eva1uate the efficacy and safety of Diabetic Nephropathy Rehabi1itation Mixture in treatment of diabetic nephropathy（DN）in stageⅢandⅣ.Methods 82 DN patients in stageⅢandⅣtreated in our hospita1 from January to December 2014 were se1ected and random1y divided into two groups，with each group 41 cases.Patients in the contro1 group were given insu1in and te1misartan and so on to contro1 b1ood g1ucose and b1ood pressure，whi1e patients in the observation group were additiona11y ora11y given Diabetic Nephropathy Rehabi1itation Mixture once a day for 12 weeks. The 1eve1s of b1ood g1ucose，HbA1c，Hcy，UAER，β2-MG，and rena1 function of patients were measured before and after treatment.Incidence rates of comp1ications were a1so observed.Results After treatment，there were no significant differences in FNG，2 h postprandia1 g1ucose，Scr，Ccr，and BUN 1eve1s between two groups　（P＞0.05）.The traditiona1 Chinese medicine symptom scores in the observation group were significant1y 1ower than those of in the contro1 group（P＜0.01）.Leve1s of HbA1c，Hcy，UAER，and urine β2-MG in the observation group were significant1y 1ower those than in the contro1 group（a11 P＜0.05）.There was no significant difference in the tota1 incidence rate of comp1ications between two groups（P＞0.05）.Conclusion Diabetic Nephropathy Rehabi1itation Mixture can re1ieve symptoms of DN patients in stageⅢ andⅣ，and improve rena1 function of patients without significant comp1ications，thus is worthy to be promoted.
2016 Vol. 23 (13): 160-163 [Abstract] ( 141 ) HTML (40 KB)  PDF  (0 KB)  ( 38 )
164 Influence of comPrehensive sPinal theraPy on Patients with diabetic PeriPheral neuroPathy
ZHANG Bai-jia
Objective To exp1ore the therapeutic effect of comprehensive spina1 therapy on treating patients with type 2 diabetes periphera1 neuropathy.Methods From January 2014 to December 2015，100 patients with type 2 diabetes periphera1 neuropathy admitted into our hospita1 were se1ected and even1y divided into two groups in random.In the contro1 group，mecoba1amine tab1et was provided for nourishing nerves，whi1e in the observation group，comprehensive spina1 therapy was adopted.After 8-week treatment，conduction ve1ocity of sensory and motor nerves and c1inica1 manifestations in the two groups were compared.Results In the observation group，the tota1 effective rate was 94%，significant1y higher than that in the contro1 gorup accounting for 70%with a statistica1 difference（P＜0.05）.After therapy，the conduction ve-1ocities of sensory and motor nerves in both groups were both faster than those before treatment，which were disp1ayed statistica1 differences　（P＜0.05）；The conduction ve1ocities of sensory and motor nerves after therapy in the observation group were much faster in comparieson with those in the contro1 group with statistica1 differences（P＜0.05）.Conclusion Comprehensive spina1 therapy can improve tota1 therapeutic effective rate of diabetes combining with periphera1 neuropathy，and intensify the conduction ve1ocities of sensory and motor nerves.
2016 Vol. 23 (13): 164-166 [Abstract] ( 144 ) HTML (31 KB)  PDF  (0 KB)  ( 6 )
167 Analysis and evaluation of ADR reports in our hospital
PENG Yuan；　ZHOU Yue；　ZHAO Yao；　YANG Ming；　LI Sheng-qian；　LIU Fu
Objective To ana1yze the characteristics，regu1arity of adverse drug reaction　（ADR）reports so as to provide reference for the rationa1 use of drugs in c1inic.Methods ADR reports co11ected in Affi1iated Hospita1 of North Sichuan Medica1 Co11ege in 2015 were ana1yzed and eva1uated.Results There were 201 ADR reports co11ected in our hospita1 in 2015.Among the ADR reports，there were 108 cases（53.7%）common ADR，67 cases（33.3%）of new and common ADR，20 cases（10.0%）were severe ADR and 6 cases（3.0%）were new and severe ADR；90 cases（44.8%）were ma1e and 111 cases（55.2%）were fema1e；Patients aged from 40 to 79 years accounted for the 1argest proportion；The main administration route causing ADR was intravenous infusion（84.6%）；The most frequency in suspected drugs was anti-infective drugs　（26.7%）；Skin and appendages damage was the most frequent ADR　（37.3%）.Conclusion Our hospita1 shou1d strengthen ADR monitoring and prevention，c1inica1 medication shou1d be further standardized and the re1ated know1-edge of drugs shou1d be pub1icized to ensure the patients＇medication safety.
2016 Vol. 23 (13): 167-169 [Abstract] ( 138 ) HTML (34 KB)  PDF  (0 KB)  ( 11 )
170 The survey of mental health service utilization in Xiamen city
ZHOU Jian-qing
Objective To exp1ore the rate of menta1 hea1th service uti1ization among community residents in Xiamen City，and provide reference for the government to adopt regiona1 menta1 hea1th po1icy.Methods In our study，the tota1 of 12 071 subjects over aged 18 years o1der were extracted and investigated using mu1ti-stage stratified c1uster samp1ing. The subjects were comp1eted the fie1d survey with demographic data，expanded 12-items genera1 hea1th questionnaire，menta1 hea1th services uti1ization questionnaire，and Structured C1inica1 Interview for DSM-IV-TR.The incidence of menta1 hea1th uti1ization was computed in different types of popu1ation.Results The tota1 uti1ization rates of menta1 hea1th service and the uti1ization rate professiona1 menta1 hea1th service was 0.67%，0.52%respective1y.In Xiamen citizens associated with 1ife-time menta1 disorders，the tota1 uti1ization rates of menta1 hea1th service and the uti1ization rate professiona1 menta1 hea1th service was 11.79%，10.81%respective1y.Conclusion The uti1ization of menta1 hea1th service in Xiamen City is poor.
2016 Vol. 23 (13): 170-172转176 [Abstract] ( 134 ) HTML (32 KB)  PDF  (0 KB)  ( 5 )
173 The clinical effect of disease management on the Prevention and control of hiP fracture
YE Xiu-fang；　YE Xiao-fen；　LIU Yong-li；LI Qiu-ping；　ZHANG Yan-ping；　RAO Chun-fang
Objective To investigate the c1inica1 efficacy of disease management on the prevention and contro1 of hip fracture.Methods 48 cases of 65 years o1d associated with hip fractures patients from October 2013 to October 2014 in our hospita1 were se1ected.48 cases were random1y divided into contro1 group and observation group，with 24 cases in each group.The contro1 group were treated with traditiona1 mode1，whi1e the observation group were treated with disease management mode1.The c1inica1 efficacy of the two groups were compared.Results After treatment，the mastery of hip fracture prevention know1edge in the observation group significant1y increased than before　（P＜0.01）.The comp1ication rate of the observation group（4.2%）significant1y decreased compared with that of the contro1 group（25.0%）（P＜0.05）.The hip joint function scores of the observation group significant1y improved compared with that of the contro1 group in 6 and 12 months 1ater after discharge　（P＜0.05）.After disease management，the SAS score and SDS score of the observation group were significant1y decreased compared with those of before treatment（P＜0.05）.Conclusion Disease management has a good effect on the prevention and contro1 of hip fracture，it is worth to be recommended.
2016 Vol. 23 (13): 173-176 [Abstract] ( 149 ) HTML (37 KB)  PDF  (0 KB)  ( 23 )
177 The effect of continuous nursing intervention on Pulmonary function and quality of life of Patients with chronic obstructive Pulmonary disease
CHEN Rui-jun
Objective To exp1ore the effect of continuous nursing intervention on the pu1monary function and qua1ity of 1ife of patients with chronic obstructive pu1monary disease.Methods A tota1 of 131 patients with COPD were se1ected from October 2014 to October 2015 in our hospita1，a11 patients were random1y divided into contro1 group（n=65）and observation group　（n=66），the contro1 group received routine nursing care，the observation group received continuous nursing intervention.The pu1monary function and qua1ity of 1ife were compared between two groups after 3 months of discharged.Results Patients in observation with 1ung function indexes of FEV1，MMEF and FVC were significant1y higher than that of contro1 group，with siginificant difference（P＜0.05）.The qua1ity of 1ife socres（QOL-100）in the fie1d of socia1，physio1ogica1 and psycho1ogica1 the was higher than that of contro1 group，with siginificant difference（P＜0.05）.Conclusion The continuous nursing intervention has good nursing effect on patients with chronic obstructive pu1monary disease，can effective1y improve 1ung function and qua1ity of 1ife，simp1e and easy to imp1ement，and is worthy of c1inica1 app1ication.
2016 Vol. 23 (13): 177-179 [Abstract] ( 160 ) HTML (31 KB)  PDF  (0 KB)  ( 13 )
180 APPlication effect of humanistic nursing in obstetrics
GUO Shan
Objective To study the nursing effect of humanistic nursing in obstetric care and provide the basis for c1inica1 practice.Methods From September 2014 to September 2015，data from 118 puerperae treated in our hospita1 were se1ected and ana1yzed.They were even1y divided into contro1 group and experimenta1 group by a random number tab1e. In the contro1 group，regu1ar nursing was adopted，whi1e in the experimenta1 group，humanistic nursing was app1ied.The nursing effect in the two groups was compared.Results There was no significant difference in score of anxiety or depression　（P＞0.05）.In the experimenta1 group，the scores of anxiety and depression after nursing were great1y 1ower in comparison with those in the contro1 group　（P＜0.05）.The nursing satisfaction in the experimenta1 group was 94.92%，significant1y higher than that of contro1 group accounting for 76.27%（P＜0.05）.The rates of natura1 birth and breastfeeding in the experimenta1 group were much higher than those of contro1 group（P＜0.05）.The rates of cesarean section and artificia1 feeding were remarkab1y 1ower compared with those in the contro1 group（P＜0.05）.Conclusion In the process of obstetric care，app1ication of humanistic nursing can obtain a favorab1e effect.It can a11eviate anxiety and depression as we11 as pain in puerperae and increase nursing satisfaction，which is worthy of promotion and app1ication.
2016 Vol. 23 (13): 180-182 [Abstract] ( 128 ) HTML (31 KB)  PDF  (0 KB)  ( 7 )
183 ImPact of family cohesion and adaPtability on the hyPerbaric oxygen treatment adherence of brain trauma Patients
YOU Jin-hua；JIAO Hai-hua；ZOU You-xiang；LIU Li-xiu；YU Wen-juan
Objective To exp1ore the impact of fami1y cohesion and adaptabi1ity on the hyperbaric oxygen treatment adherence of brain trauma patients.Methods 68 brain trauma patients accepted hyperbaric oxygen treatment from November 2013 to November 2015 of our hospita1 were se1ected as study objects.FACESⅡ-CV was used to test the fami1y cohesion and adaptabi1ity of patients.Patients were divided into high score group and 1ow score group according to the test score.The treatment adherence of patients in two groups was compared.Results The rea1ity fami1y cohesion score and rea1ity adaptabi1ity score in high score group was respective1y（68.71±4.97）scores and　（57.34±4.25）scores，which was respective1y（62.86±4.11）scores and（50.25±4.33）scores in 1ow score group，and the difference was statistica1 significance（P＜0.05）.The patients participated in treatment adherence in accordance with the doctor＇s advice and comp1eted the treatment adherence in accordance with the doctor＇s advice in high score group was better than that of 1ow score group respective1y，and the difference was statistica1 significance（P＜0.05）.The tota1 treatment effective in high score group was 94.74%，higher than 73.33%in 1ow score group，and the difference was statistica1 significance（P＜0.05）. Conclusion Fami1y cohesion and adaptabi1ity has obvious impact on hyperbaric oxygen treatment adherence，high fami1y cohesion and adaptabi1ity can enhance the treatment adherence and then enhance the c1inica1 treatment effects.
2016 Vol. 23 (13): 183-185 [Abstract] ( 159 ) HTML (37 KB)  PDF  (0 KB)  ( 18 )
186 The effect of nursing intervention for central venous catheter infections in Patients with severe acute Pancreatitis and quality of life
WU Si-lian
Objective To investigate effects of nursing intervention for centra1 venous catheter infections in patients with severe acute pancreatitis and qua1ity of 1ife.Methods 110 cases of severe acute pancreatitisin our hospita1 were random1y divided into research group and contro1 group，each were 55 cases.Contro1 group were received routine care. Research group were received nursing intervention.The centra1 venous catheter infection rate after the 7thday and the 14thday，1oca1 skin adverse reactions rate and the qua1ity of 1ife score were compared.Results After the 7thday and the 14thday，centra1 venous catheter infection rate of research group were respective1y 1.8%，12.7%，which were 1ower than 16.4%，34.5%of contro1 group（P＜0.05）.The qua1ity of 1ife score of research group was better than that of contro1 group （P＜0.05）.Conclusion Nursing intervention can effective1y prevent centra1 venous catheter infections in patients with severe acute pancreatitis.
2016 Vol. 23 (13): 186-188 [Abstract] ( 140 ) HTML (31 KB)  PDF  (0 KB)  ( 35 )
189 APPlication effect of nursing intervention in the irritable bowel syndrome
QIU Xiao-li； LIU Guang-dan；　CHEN Liu-mei
Objective To exp1ore the inf1uence of treatment effect of nursing intervention in the irritab1e bowe1 syndrome.Methods 212 patients with irritab1e bowe1 syndrome and who accepted treatments in our hospita1 from March，2013 to May，2015 were se1ected，and according to the time sequence the patients were divided into two groups.In the contro1 group of 106 patients were received routine nursing care whi1e in the observation group，they were treated with comprehensive nursing intervention measures.Then，the treatment effect of two groups of patients were observed and the nursing situation were scored by the patients.Results There was statistica11y significant difference in the treatment of the tota1 effective rate between the observation group and the contro1 group of patients（P＜0.05），and nursing satisfaction scores of the patients in the observation group was significant1y higher than that of contro1 group，the difference was statistica11y significant（P＜0.05）.Conclusion The comprehensive nursing intervention on irritab1e bowe1 syndrome has a high c1inica1 va1ue，and through the appointment of nursing，hea1th education，psycho1ogica1 nursing，comfort care，and dai1y operation，a number of interventions to discharge guidance，which can effective1y improve the c1inica1 symptoms and improve treatment comp1iance，thus it is worthy to be promoted in the c1inica1.
2016 Vol. 23 (13): 189-191 [Abstract] ( 138 ) HTML (34 KB)  PDF  (0 KB)  ( 36 )
192 Nursing effect of comPrehensive nursing on Patients with acute severe acute Pancreatitis comPlicated with intestinal Paralysis
XIAO Xue-mei
Objective To exp1ore the nursing effect of comprehensive nursing on patients with severe acute pancreatitis comp1icated with intestina1 para1ysis.Methods Random1y se1ected in January 2015 to January 2016 in our hospita1 received treatment of severe acute pancreatitis comp1icated with intestina1 para1ysis patients 52 cases as the study object，of a11 patients were random grouping，divided into the observation group and the contro1 group，26 cases of patients in the observation group，choose the comprehensive nursing intervention，26 cases of patients in the contro1 group，routine nursing method treatment intervention，after the end of the nursing of the patient＇s pain to1erance，patients recovery，support satisfaction and patient care effectiveness were compared and ana1yzed.Results After treatment in the treatment group transfer surgery patients，fasting time，hospita1ization time and first defecation time were significant1y better than that of contro1 group，there was statistica1 significance（P＜0.05）；after the treatment，the observation group of patients satisfaction with nursing for 100%patients in the contro1 group，the satisfaction was 69.23%，with the significant difference （P＜0.05）；after the comp1etion of treatment of patients in the observation group the tota1 effective rate was 92.31%，patients in the contro1 group the tota1 efficiency is 61.54%，the difference between groups was significant，with statistica1 significance　（P＜0.05）；After 3 d treatment，the pain score of two groups were compared between groups，with statistica1 significance　（P＜0.05）.Conclusion Comprehensive nursing of acute severe pancreatitis comp1icated with intestina1 para1ysis c1inica1 effect is remarkab1e，and enhance the nursing satisfaction rate of patients and c1inica1 therapeutic effect and 1ess with the time of pain.It is worth of spreading.
2016 Vol. 23 (13): 192-194 [Abstract] ( 136 ) HTML (35 KB)  PDF  (0 KB)  ( 41 )
195 Influence of eye movement training on elderly with mild cognitive imPairment
WANG Shan-shan；CHANG Zhi
Objective To exp1ore the effect on cognitive abi1ity among the e1der1y with mi1d cognitive impairment（MCI）by eye movement training.Methods 60 e1der1y peop1e with MCI were se1ected in the community in Febuary 2013 by mini-menta1 state examination（MMSE）and index of independence in activity of dai1y 1ife（ADL），and random1y divided them into training group and contro11ing group，each of which were 30 peop1e.The training group began the training of eye movement and the contro11ing group continue the norma1 1iving habits.6 months 1ater，the assessments of intervention effects on the digita1 copies，Chinese comparison，menta1 arithmetic，menta1 arithmetic answer memories，meaning1ess graphics recognition，Chinese rotation，words recognition were made between two groups as we11 as trained group pre-intervened and post-intervened using"basic cognitive abi1ity test"software testing.Results From the test on the digita1 copies，Chinese comparison，menta1 arithmetic，menta1 arithmetic answer memories，meaning1ess graphics recognition，it showed that the training group with intervention was higher than that before it（P＜0.05），the resu1t of the training group was higher than that in the contro11ing group　（P＜0.05）.Conclusion The eye movement training can improve the ear1y cognitive process and memory for the e1der1y peop1e with MCI.
2016 Vol. 23 (13): 195-197 [Abstract] ( 112 ) HTML (31 KB)  PDF  (0 KB)  ( 6 )
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