多沙唑嗪缓释片改善输尿管支架管相关症状的非随机-对照研究

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Abstract Objective To discuss the effect of Doxazosin Sustained Re1ease Tab1ets in improving associated symptoms of urethra1 stent.Methods 58 patients with urethra1 stent after operations due to urinary ca1cu1us treated in our hospita1 from March to September 2014 were se1ected and divided into study group（n=24）and contro1 group（n=34）.For patients in the contro1 group，catheters were removed after 1-3 days of operation，antibiotics were ora11y administrated for infection prevention，and urethra1 stents were removed after 2-4 weeks of operation.Patients in the study group were additiona11y ora11y given Doxazosin Mesy1ate Sustained Re1ease Tab1ets 4 mg，qd，for 2-4 weeks.IPSS，QOL，and VAS sca1es were accomp1ished separate1y before removing the stents.Results There were significant differences in IPSS scores，QOL scores and VAS scores［（9.12±0.99）scores vs（11.65±1.39）scores，t=7.616，P=0.000；（2.21±0.59）scores vs（2.68± 0.84）scores，t=2.345，P=0.023；（1.54±0.59）scores vs　（1.97±0.67）scores，t=2.514，P=0.015］between the study group and the contro1 group.There was no significant difference in incidence of hematuria　（37.50%vs 44.12%，χ2=0.254，P=0.614）. Conclusion Doxazosin Sustained Re1ease Tab1ets can re1ieve associated symptoms of urethra1 stent and improve 1iving qua1ity of patients.

Key words： Doxazosin Sustained Re1ease Tab1ets Associated symptoms of urethra1 stent Urinary ca1cu1us

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	Articles by authors
	ZHANG Nan
	KONG Su-fang
	GE Lei
	GUO Liang
	MA Yao-hui
	QU Xiao-wei
	SHAN Zhong-jie

Cite this article:

ZHANG Nan,　KONG Su-fang,　GE Lei, et al. Non randomized controlled study on Doxazosin Sustained Release Tablets in imProving associated symPtoms of urethral stent[J]. 中国当代医药, 2016, 23(13): 148-150.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I13/148

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