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Quick Search     Adv Search 2018 Vol. 25, No. 27 Published: 2018-09-28   4 Effect comparison of supraclavicular brachial plexus block of different concentration and same dose Ropivacaine under ultrasound guidance LONG Xiao-fei;FANG Xiao-wei;ZHOU Bin;CAO Jian;YU Shu-chun;LUO Zhen-zhong Objective To comparison the supraclavicular brachial plexus block effect of different concentration and same dose Ropivacaine under ultrasound guidance.Methods A total of 90 patients given unilateral upper limb surgery in our hospital from May 2015 to May 2017 were selected and they were randomly divided into three groups,and there were 30 patients in each group.Group A received 40 ml of 0.25%Ropivacaine,group B received 20 ml of 0.5%Ropivacaine,and group C received 13.3 ml of 0.75%Ropivacaine.Onset and duration time of sensory and motor block of each nerve(musculocutaneous nerve,radial nerve,ulnar nerve,median nerve),the success rate of block and the incidence of complications among the three groups were compared.Results Drug injection time in group A was significantly longer than that in group B and C,and the differences were statistically significant(P＜0.05).There was no significant difference in the onset time of sensory block for each nerve in patients among the three groups(P＞0.05),the duration time of sensory block in patients of group B was significantly longer than that in group A and C,and group A was longer than that in group C,and the differences were statistically significant(P＜0.05).The success rate of sensory block in patients of group A and group B were significantly higher than those in group C,and the differences were statistically significant(P＜0.05).The onset time of motor block for each nerve in patients of patients of group A was significantly longer than that in group B and C,and the differences were statistically significant(P＜0.05),and the duration time of motor block in patients of group B was significantly longer than that in group A and C,and group A was significantly longer than that in group C,and the differences were statistically significant(P＜0.05).The success rate of motor block in patients of group A and B were significantly higher than those in group C,and the differences were statistically significant(P＜0.05).The total incidence of complications in group A was higher than that in group B and C,and the differences were statistically significant(P＜0.05).Conclusion0.5%Ropivacaine of the same dose(100 mg)has a rapid onset,a long duration,a high success rate and a low incidence of complications for supraclavicular brachial plexus block under ultrasound guidance. 2018 Vol. 25 (27): 4-7 [Abstract] ( 140 ) HTML (45 KB)  PDF  (0 KB)  ( 27 ) 8 The influence of Endostatin 30 peptide on proliferative activity and adhesion ability of HepG2 cell YU Jia-qi;ZHAO Hang;YANG Yang;WEI Xing-peng;NIU Shu-dong;LI Shu-yan Objective To investigate the influence of Endostatin 30 peptide on proliferative activity and adhesion ability of HepG2 cell for liver cancer.Methods The nucleotide sequences corresponding to amino-terminal 1-31 amino acids of endostatin(change the 25-31 bit sequence from RGIRGAD to RGDRGD)were linked to plasmid pTYB2,then converted to the expression of Escherichia coli BL21 (DE3)and synthesize 30 peptides composed of 30 amino acids.Results After HepG2 cells were treated by 30 peptide of 0,20,40,60,80,100 μg/ml for 24,48 h,the proliferative activity and adhesion of cells were inhibited in time and dose dependent,and compared with the control group,there was a significant difference (P＜0.05).Conclusion Endostatin 30 peptide can effectively inhibit the proliferation and adhesion of HepG2 cell,which is expected to become one of the adjuvant therapies for liver cancer. 2018 Vol. 25 (27): 8-10转19 [Abstract] ( 152 ) HTML (40 KB)  PDF  (0 KB)  ( 27 ) 11 Correlation study between WCST executive function and five factor score of PANSS in patients with schizophrenia at acute stage XIAO Jian-wen;HUANG Li;SHEN Ying Objective To explore the correlation between Wisconsin card classification test(WCST)executive function and five factor score of PANSS in patients with schizophrenia at acute stage.Methods Patients with schizophrenia at acute stage hospitalized in our hospital from May to November 2017 were selected and 200 patients were included in the plan.The relevant demographic data and disease data in patients included were counted,such as age,age of onset,course of disease,length of education,etc.WCST was used to assess the executive function of the patients at the end of the first week of treatment.Total test times,correct response number,persistent error number,random error number and completing classification number were counted.At the end of the first week of treatment,positive and negative symptom scale(PANSS)was used to assess the psychiatric symptoms of patients in acute stage.Principal component analysis was performed on 30 items of PANSS,among them,9 items forming negative factors,7 items forming cognitive factors,4 items forming positive factors,4 items forming excitatory factors and 6 items forming anxiety and depression factors.The score of various factor was calculated respectively.Results WCST executive function scores of patients with different educational years,different age of onset and different negative and positive scores of PANSS were statistically significant(P＜0.05).The educational years of the patients was negatively correlated with the total tests number,persistent error number and random error number(r=-0.01,-0.23,-0.18)respectively,and the educational years of the patients was positively correlated with correct response number,completing classification number(r=0.35,0.37)respectively.The age of onset was negatively correlated with persistent error number and random error number(r=-0.14,-0.35)respectively,and the age of onset was positively correlated with total test times,correct response number,completing classification number(r=0.31,0.17,0.14)respectively.The positive score of PANSS was negatively correlated with total test times,persistent error number and random error number (r=-0.09,-0.05,-0.08)respectively,and the positive score of PANSS was positively correlated with correct response number,completing classification number(r=0.17,0.15)respectively.The negative scoer of PANSS was negatively correlated with correct response number,completing classification number(r=-0.13,-0.36)respectively,and the negative score of PANSS was positively correlated with total test times,persistent error number and random error number(r=0.35,0.26,0.25)respectively.Pearson correlation analysis showed that the correct response number and completing classification number of WCST executive function were negatively correlated with negative symptom score of PANSS,and the persistent error number and random error number were positively correlated with negative symptom score,while the other items were not significantly correlated.Conclusion WCST executive function defect exists in patients with schizophrenia at acute stage,and it has certain correlation with negative symptoms.The study of executive function in patients with schizophrenia at acute stage will be more conducive to diagnosis,disease prediction,prognosis judgment,treatment and rehabilitation of patients. 2018 Vol. 25 (27): 11-15 [Abstract] ( 143 ) HTML (45 KB)  PDF  (0 KB)  ( 28 ) 16 Clinical effect of Carapacis Trionycis Bolus treating hepatitis cirrhosis LI Heng-fei;YAN Deng-ying;XU Jian;CHEN Qin Objective To explore the clinical effect of Carapacis Trionycis Bolus treating hepatitis cirrhosis.Methods A total of 86 patients with hepatitis cirrhosis treated in Hubei Provincial Traditional Chinese Medical Hospital from February 2013 to February 2017 were selected as the study subjects,and they were divided into the the control group(n=43)and observation group(n=43)according to the order of medical treatment.The control group was treated by routine western medicine,mainly using Entecavir Dispersible Tablets,while the observation group was treated by combined method:Entecavir Dispersible Tablets+Carapacis Trionycis Bolus.HBV-DNA negative condition,liver function index and liver fibrosis before and after treatment were compared between the two groups.Results The negative rate of HBV-DNA was 44.19%in the 12thweek,and it was 58.14%in the 24th week and 93.02%in the 48thweek in the observation group,which was higher than that of the control group (25.58%,32.56%,48.84%)respectively,and the differences were statistically significant(P＜0.05).There was no significant difference in the levels of STB,ATL and ALB before treatment between the two groups(P＞0.05),after treatment,the levels of STB and ATL were lower than those before treatment,and the levels of ALB were higher than those before treatment in the two groups,and the differences were statistically significant(P＜0.05),after treatment,the levels of STB and ALB in the observation group were higher than those in the control group,and the level of ATL was lower than that in the control group (P＜0.05).There was no significant difference in the levels of CL-Ⅳ,PCⅢ,LN and HA before treatment between the two groups(P＞0.05).After treatment,the levels of CL-Ⅳ,PCⅢ,LN and HA in the two groups were significantly lower than those before treatment,and the differences were statistically significant(P＜0.05).The levels of CL-Ⅳ,PCIII,LN and HA in the observation group were lower than those in the control group after treatment,and the differences were statistically significant(P＜0.05).Conclusion Carapacis Trionycis Bolus treating hepatitis cirrhosis can inhibit HBV-DNA polymerase to a certain extent,reduce HBV replication,alleviate liver inflammation and fibrosis,reduce the incidence of canceration and complications,clinical effect is satisfactory,and it is worthy of further promotion and application. 2018 Vol. 25 (27): 16-19 [Abstract] ( 155 ) HTML (41 KB)  PDF  (0 KB)  ( 31 ) 20 Clinical observation of minimally invasive plasmakinetic prostatic resection treating high-risk benign prostatic hyperplasia CHENG Xian-rui;WANG Yu-xiang;CHEN Zi-hua;ZHU Ke-he;DONG Zhen-hua;ZHANG Yong-jian Objective To investigate the clinical effect of minimally invasive plasmakinetic prostatic resection treating high-risk benign prostatic hyperplasia.Methods A total of 74 patients with benign prostatic hyperplasia treated by surgery in our hospital from November 2015 to November 2017 were selected as the research objects,and they were divided into the control group (37 cases)and treatment group (37 cases)according to the random grouping method.The control group was treated with traditional transurethral resection of the prostate,while the treatment group was treated with minimally invasive plasmakinetic prostatic resection.The preoperative and postoperative urethral function,quality of life,psychological status,and total effective rate of surgical treatment,postoperative complications,satisfaction with surgical methods and achieving effect,operation time,urethral indwelling time,bladder irrigation time,postoperative hospital stay,bleeding volume during operation were compared in patients bieween the two groups.Results The indexes of urethral function,quality of life and mental state score in the two groups were higher than those before treatment,and the differences were statistically significant(P＜0.05).There was no significant difference of the above-mentioned indexes between the two groups before treatment(P＞0.05),and there were significant differences of the above-mentioned indexes between the two groups after treatment(P＜0.05).The total effective rate after surgery treatment in the treatment group was higher than that of the control group,and the total satisfaction degree of the treatment group was higher than that of the control group(P＜0.05).The incidence of postoperative complications was 2.7%(1/37)in the treatment group,which was lower than that of the control group (16.2%,6/37),and the difference was statistically significant(P＜0.05).The operation time,catheter retention time,bladder irrigation time and postoperative hospitalization time of the treatment group were shorter than those of the control group(P＜0.05),and the amount of bleeding during operation was less than that of the control group(P＜0.05).Conclusion Minimally invasive plasmakinetic prostatic resection treating high-risk benign prostatic hyperplasia can improve the urethral function in a short time,keep the patients in good psychological state and improve their quality of life,and it can shorten the operation time and postoperative recovery time,reduce the amount of bleeding during operation and the occurrence of related adverse reactions,and promote the treatment effect and satisfaction degree of patients simultaneously. 2018 Vol. 25 (27): 20-23 [Abstract] ( 147 ) HTML (42 KB)  PDF  (0 KB)  ( 38 ) 24 Research progress in cardiovascular risk associated with antidepressants WANG Long-fei;GONG Shan;YU Guo-long Depression incidence rate is high in patients with cardiovascular disease (CVD).Depression increases risks of adverse cardiovascular events including all-cause mortality and cardiovascular disease mortality in patients with CVD.Therefore,it is necessary to treat including drug treatment for CVD patients combined with depression disorder.There are significant differences in the safety and effectiveness of different types of antidepressants in clinical use.In this paper,based on recent clinical researches about different types of antidepressants,it focus on cardiovascular risks associated with the new antidepressants commonly used in patients.The purpose is to help clinicians correctly to choice antidepressants for patients. 2018 Vol. 25 (27): 24-27 [Abstract] ( 146 ) HTML (43 KB)  PDF  (0 KB)  ( 25 ) 28 Research progress of calcitonin gene-related peptide in the treatment of migraine WANG Fei Calcitonin gene-velatdecl peptide (CGRP)is a neuropeptide with potent vasodilator effect.It is closely related to the onset of migraine.With the study of the role of CGRP in the migraine'mechanism,a series of CGRP's drugs treating migraine have been developed,mainly including CGRP receptor antagonists and CGRP monoclonal antibody.This article reviews the progress of CGRP in the treatment of migraine. 2018 Vol. 25 (27): 28-31 [Abstract] ( 103 ) HTML (42 KB)  PDF  (0 KB)  ( 22 ) 32 Effect of acupuncture on neuronal apoptosis and adenosine level in rats with transient ischemic attack ZHANG Jun;LIU Min;TANG Wei;WANG Wei Objective To study the effect of acupuncture on apoptosis and adenosine level of neurons in rats with transient ischemic attack(TIA).Methods 32 male Wistar rats are randomly divided into 4 groups,normal control group(8 rats),sham-operation group(8 rats),model group(8 rats),acupuncture group(8 rats).Global cerebral ischemia TIA rat model was established by four-vessel occlusion.The acupuncture group was adminstered with electro acupuncture therapy and other 3 groups without any other treatment,to sample 1 week after surgery.By the TUNEL dyeing test(In situ terminal labeling)to detect the Neuron apoptosis in cerebral cortex and hippocampus CA1 area,and determine Adenosine content in cerebral cortex and hippocampus area by spectrophotometer.Results The neuronal apoptosis in the CA1 area and cerebral cortex of the model group were (36.44±8.96),(36.94±8.77)single/mm2higher than that of the acupuncture group (18.52±6.32),(20.11±6.70)single/mm2 with significant difference(P＜0.05）.As for normal control group and the sham operation group,the values were(13.98±5.47),(11.63±4.55)single/mm2 both lower than that of model group,with statistical difference (P＜0.05）.Adenosine content： the CA1 area and cerebral cortex of the model group were(0.139±0.016)and(0.140±0.017)μmol/L mg,lower than that of the acupuncture group(0.176±0.004)(0.178±0.006)μmol/L mg,with statistical difference(P＜0.05）.As for normal control group(0.038±0.006),(0.039±0.009)μmol/L mg and the sham operation group(0.037±0.006),(0.038±0.005)μmol/L mg were lower than the model group,and the difference was statistically significant(P＜0.05）.Conclusion Acupuncture can inhibit the apoptosis of neurons in TIA rats and increase the content of endogenous adenosine in them. 2018 Vol. 25 (27): 32-34 [Abstract] ( 162 ) HTML (39 KB)  PDF  (0 KB)  ( 28 ) 35 Research on improving the iron-deficiency anemia in rats by Huangqi E-jiao Butie Oral Solution LIN Jian;ZHANG Wei-hua;LIN Wei;GONG Xiu-xiu;ZHONG Li-yun;CHEN Guan-min Objective To get known the effect of Huangqi Ejiao Butie Oral Solution in improving iron-deficiency anemia.MethodsSeventy-four rats were selected.The an animal model of anemia using iron-deficiency diet was established.These rat models were divided into the low-,medium-,and high-dose sample groups and low-iron group by random block based on the hemoglobin (Hb)level,3.33 ml/kg BW,6.67 ml/kg BW and 20.0 ml/kg BW,and deionized water for 32-day intragastric administration in turn.The rats'weight,Hb,hematocrit(Hct)and free erythrocyte protoporphyrin (FEP)were observed.Results There was no significant difference in rat body weight in these sample groups compared with low-iron control group(P＞0.05）.The Hb(F=161.156)and Hct(F=78.771)in the three dose groups using Huangqi Ejiao Butie Oral Solution were significantly higher than those in the low-iron control group(P＜0.05）.The value of FEP(F=170.516)was significantly lower compared with that in the low-iron control group,the differences were statistically significant(P＜0.05）.Conclusion Huangqi Ejiao Butie Oral Solution can improve iron-deficiency anemia. 2018 Vol. 25 (27): 35-37 [Abstract] ( 165 ) HTML (40 KB)  PDF  (0 KB)  ( 27 ) 38 Comparison of naringin content in Exocarpium Citri Grandis fruits at different diameters LI Qiong-xia;LI Xiao-xin;XIE Cheng-en;LIAO Hui Objective To compare the difference in naringin content between fruits of Exocarpium Citri Grandis at different diameters using high performance liquid chromatography (HPLC).Methods A total of 25 batches of Exocarpium Citri Grandis fruits at different diameters were crushed through No.3 sieve,and naringin was extracted by ultrasonic extraction with methanol.The column of Gemini C18(4.6 mm×250 mm,5 μm)was used,the mobile phase was methanol and 6%acetic acid water with the ratio of 35:65,the flow rate was 1.0 ml/min,the column temperature was 25°C.The detection wavelength was 283 nm,and sample injection in 20 μl was for detection.Results The standard curve of the determination method was y=16.8568x+3.2460 (r=0.9999),and the linearity was good in the range of 0-80 μg/ml.The lowest quantitative concentration was 6.67 μg/ml(signal to noise ratio was 10:1).The average recovery rate of three concentrations was 99.66%,and the RSD was 1.2%.The repeatability,precision,and stability all met the requirements.The naringin content was between 3.26%and 28.56%.Conclusion There is a significant difference in the content of naringin in Exocarpium Citri Grandis fruits at different diameters,which is worth promoting young fruit of Exocarpium Citri Grandis as a medicinal resource. 2018 Vol. 25 (27): 38-41 [Abstract] ( 151 ) HTML (41 KB)  PDF  (0 KB)  ( 30 ) 42 Analysis of uncertainty for the determination of copper in Astragali Radix by the flame atomic absorption spectrophotometric method WEI Zhi-xiong;LIU Dan-dan;LAN Ming-xiong;WANG Kun-peng Objective To establish a method for the uncertainty evaluation in the determination of copper in Astragali Radix by flame atomic absorption spectrophotometric (FAAS).Methods The uncertainty factors arising from reference solution preparation,ample solution preparation,sample repetitiveness,and calibration curve fitting were evaluated according to Measurement Uncertainty and Representation of Measurement(JJF1059.1-2012),and the final measurement results were given after measurement of the component uncertainty.Results The content of copper in Astragali Radix of this research was 4.00 mg/kg,and the expanded standard uncertainty was 0.38 mg/kg (including factor k=2).Conclusion The method is applicable to the uncertainty evaluation of the determination of components in traditional Chinese medicine by FAAS. 2018 Vol. 25 (27): 42-44转57 [Abstract] ( 139 ) HTML (45 KB)  PDF  (0 KB)  ( 25 ) 45 Ultrastructural changes of duodenal mucosa in patients with malnutrition and its significance ZHU Hai-yan;WU Xiong-jian Objective To observe the ultrastructural changes of duodenal mucosa in malnourished patients and explore its significance.Methods Eighteen patients with malnutrition due to ingestion disorders performed with nasogastric cathelerization or nasojejunal cathelerization under electronic gastroscopy in our hospital from October 2012 to May 2015 were selected.Conventional endoscopic biopsy was performed during electronic gastroscopy for patient's duodenal mucosa,which was examined by transmission electron microscope to observe its ultrastructure.The malnutrition patients with or without ultrastructural changes in duodenal mucosa were classified into positive and negative groups,respectively.The levels of plasma hemoglobin,total protein,albumin,prealbumin and transferrin were tested in the two groups.The relationship between ultrastructural changes of duodenal mucosa and the above indexes were analyzed.Results Of 18 patients,10 were detected with ultrastructural changes of duodenal mucosa,and the incidence was 55.6%.The ultrastructural changes of duodenal mucosa were manifested as sparse microvilli of epithelial cells in disorganized arrangement,widened intercellular junction space and swollen organelles.The levels of plasma albumin and transferrin decreased significantly in the positive group compared with those in the negative group (P＜0.05),but the levels of hemoglobin,total protein and prealbumin were not significantly different(P＞0.05).Conclusion There are ultrastructural changes of duodenal mucosa in patients with malnutrition,and the changes are of great significance for reflecting patient's nutritional status,intestinal environment and function. 2018 Vol. 25 (27): 45-47 [Abstract] ( 133 ) HTML (35 KB)  PDF  (0 KB)  ( 14 ) 48 Application of Shengji Chuanyu ointment combined with microwave irradiation in promoting wound healing after anal fistula operation WU Yun-xiang;TANG Yong;CHEN Guang-hua;AN Ming-wei;ZHANG Lei-chang Objective To explore the application value of Shengji Chuangyu ointment combined with microwave irradiation in promoting wound healing after anal fistula operation.Methods From May 2014 to January 2018,80 patients of anal fistula operation in our hospital were selected as the subjects,and divided into control group and observation group by random number table method,with 40 cases in each group,The patients in the control group were treated with red ointment gauze combined with microwave irradiation,and patients in the observation group were treated with Shengji Chuanyu ointment gauze combined with microwave irradiation.After 14 days of treatment,the wound exudate score,wound pain score,anal function score,wound granulation score and the clinical efficacy of the two groups were compared.Results After treatment,the wound exudate score,wound pain score,anal function score and wound granulation score of the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,the score of percolation of wound,wound pain,anal function and wound granulation were lower than those in the control group(P＜0.05).The total effective rate of the observation group(97.50%)was higher than that of the control group(77.50%),the difference was statistically significant(P＜0.05).Conclusion Shengji Chuanyu ointment combined with microwave irradiation can promote wound healing after anal fistula surgery,and which is worthy of promotion. 2018 Vol. 25 (27): 48-50 [Abstract] ( 135 ) HTML (35 KB)  PDF  (0 KB)  ( 23 ) 51 The application value of pepsinogen combined with gastroscopy and Fuji energy electronic spectroscopic image processing technology in the diagnosis of gastric precancerous lesions TONG Chun-hua Objective To investigate the application value of pepsinogen combined with pigmented gastroscopy and Fuji electron spectrographic image processing (FICE)in the diagnosis of gastric mucous precancerous lesions.Methods A total of 76 patients with gastric precancerous lesions confirmed by pathology from August 2016 to October 2017 were selected as the subjects,and randomly divided into control group and study group,38 cases in each group.The control group was treated with gastroscopy before treatment,while the study group was treated with Pepsinogen,gastroscopy and FICE before treatment.The application value between the two groups ws compared.Results The rate of misdiagnosis and missed diagnosis in the study group were lower than those in the control group.The incidence of the cause of the diagnosis was only 2.6%,less than 13.2%of the control group.The coincidence rate of the results before treatment and the results after treatment was 94.7%,higher than that of the control group.The time of examination was longer than that of the control group.The diagnosis of the disease was longer than that of the control group.The satisfaction rate of the scheme was 97.4%,which was higher than 84.2%of the control group,the differences were statistically significant(P＜0.05).Conclusion The patients with precancerous lesions of the gastric mucosa are diagnosed by Pepsinogen,pigment gastroscopy and FICE technology.Although the operation time will be prolonged,the accuracy of the examination can be improved,the misdiagnosis and missed diagnosis can be reduced,the incidence of disputes can be reduced,and which can improve the patient's satisfaction with the clinical diagnosis. 2018 Vol. 25 (27): 51-53 [Abstract] ( 126 ) HTML (35 KB)  PDF  (0 KB)  ( 19 ) 54 Application effect of comprehensive intervention in patients with non-alcoholic fatty liver disease LIU Yan-hong;CHEN Shao-wen;ZHOU Nan-nan Objective To explore the application effect of comprehensive intervention in patients with non-alcoholic fatty liver disease (NAFLD).Methods A total of 56 cases of patients with NAFLD treated in our hospital from January 2016 to January 2017 were selected as the subjects,and randomly divided into intervention group and control group,with 28 cases in each group.The intervention group were given the comprehensive intervention,while the control group were given routine intervention.The changes of liver function,uric acid,blood lipid,blood sugar and liver hardness of patients were observed.Results After the intervention,the levels of ALP,AST and ALT of two groups were decreased,and the index in the intervention group were lower than those in the control group,the differences were statistically significant(P＜0.05).After the intervention,the TC,TG,FBG,FINS and CAP value of FibroScan fat content in the intervention group was significantly lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion The comprehensive intervention for patients with NAFLD can help patients establish healthy lifestyles,control blood sugar and improve their liver function,which is worthy to be promoted in the clinical. 2018 Vol. 25 (27): 54-57 [Abstract] ( 117 ) HTML (37 KB)  PDF  (0 KB)  ( 21 ) 58 Influence of large dose ulinastatin combined with alprostadil on inflammatory cells in patients with pyemia YAN Zhi-jie Objective To investigate the effect of large dose ulinastatin combined with alprostadil on inflammatory cells in patients with pyemia.Methods A total of 78 patients with pyemia treated in our hospital from June 2016 to October 2017 were selected as the research object.According to the random number table method,the patients were divided into the control group and the observation group,with 39 cases in each group.The control group was treated with conventional dose ulinastatin combined with alprostadil,the observation group was treated with large dose ulinastatin combined with alprostadil,the two groups were treated for 4 weeks.The level of IL-6,IL-8,TNF-alpha,IL-10,WBC,CRP,Cr,ALT and other indicators,and adverse reactions and other specific circumstances were compared between the two groups after treatment.Results The levels of TNF-a,IL-6 and IL-8 in the observation group were lower than those in the control group,IL-10 in the observation group was higher than that in the control group after treatment,the difference was statistically significant(P＜0.05).The levels of WBC,CRP,Cr and ALT after treatment in the observation group were lower than those in the control group,the difference was statistically significant(P＜0.05),and no adverse reactions occurred in the two groups.Conclusion The treatment of pyemia with large dose of ulinastatin combined with prostadil has good clinical effect.It can significantly improve the clinical symptoms of sepsis,prevent hepatorenal syndrome,and has high safety.It is worthy of clinical application. 2018 Vol. 25 (27): 58-60 [Abstract] ( 123 ) HTML (32 KB)  PDF  (0 KB)  ( 17 ) 61 Clinical effect of insomnia treated with hand acupuncture combined with body acupuncture WANG Hui;LIU Sheng-hai;WANG Hai-feng;YANG Li-dong;SUN Yi-na Objective To evaluate the clinical effect of insomnia treated with hand acupuncture combined with body acupuncture.Methods From January 2013 to December 2015,92 cases patients of insomniacs treated in our hospital were selected as the research objects,and divided into treatment group and control group according to the method of random double-blind distribution,with 46 cases in each group.The treatment group with insomnia were given hand acupuncture combined with body acupuncture,the treatment,group given conventional western medicine zopiclone and oryzanol treatment.The therapeutic effects of the two groups were compared.ResultsThe total effective rate of the treatment group was 97.8%,higher than 80.4%of the control group,the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the treatment group was lower than that in the control group,the difference was statistically significant(P＜0.05).The cured patients were followed up for 6 months without relapse.Conclusion Hand acupuncture combined with body acupuncture has obvious effect on insomnia and no obvious adverse reactions.It is an ideal treatment method and should be popularized. 2018 Vol. 25 (27): 61-64 [Abstract] ( 127 ) HTML (48 KB)  PDF  (0 KB)  ( 18 ) 65 Efficacy observation of thrombolytic therapy with Alteplase for patients with acute extending thrombolytic time window cerebral infarction guided by CT LIAO Xiang-ming Objective To study the clinical effect of thrombolytic therapy with Alteplase for patients with acute extending thrombolytic time window cerebral infarction guided by CT.Methods From October 2015 to March 2018,56 patients with acute ischemic stroke and reached hospital within 6 hours and received intravenous thrombolysis treated in Department of Emergency of our hospital were selected as the subjects.They were divided into group A and group B by the onset to treatment time.Group A was rt-PA therapy started 0～4.5 h (30 cases),group B was rt-PA therapy started 4.5～6.0 h (26 cases).They all received standard dose intravenous rt-PA thrombolytic therapy,the patient of group B received multimodal CT.The patients of the two group patients have a normal CT scan in 24 h after intravenous thrombolysis.The NIHSS score at different time and the adverse effects were recorded.Results The NIHSS scores after intravenous thrombolysis([3.8±1.8]points)were lower than that before intravenous thrombolysis([11.6±3.2]points)in group A,the difference was statistically significant(P＜0.05).The NIHSS scores after intravenous thrombolysis ([4.5±2.7]points)were lower than that before intravenous thrombolysis([13.1±2.3]points)in group B,the difference was statistically significant(P＜0.05).The NIHSS scores after 7 d treatment in group A was lower than that in group B,the difference was statistically significant(P＜0.05).There was no statistical significance in the adverse effects incidence between the two groups.Conclusion Intravenous thrombolysis with rt-PA in patients with acute extending thrombolytic time window cerebral infarction guided by CT can significantly improve the blood perfusion,promote the recovery of neurological function,and is safety. 2018 Vol. 25 (27): 65-67 [Abstract] ( 125 ) HTML (34 KB)  PDF  (0 KB)  ( 21 ) 68 Clinical study on Eucalyptol Linonene Pinene Enteric Soft Capsules in the treatment of cough caused by postnasal drip syndrome WAN De-hua;WANG Ting Objective To investigate the application effect of Eucalyptol Linonene Pinene Enteric Soft Capsules in the treatment of cough caused by postnasal drip syndrome.Methods A total of 100 patients with cough caused by postnasal drip syndrome treated in the First Affiliated Hospital of Jiangxi Medical College from November 2017 to February 2018 were selected as the research object,and they were divided into two groups according to random number table method,with 50 cases in each group.The patients in the control group were treated with antibiotics+Desloratadine Tablets+nasal angiotonics,while the patients in the observation group were treated with Eucalyptol Linonene Pinene Enteric Soft Capsules on the basis of control group.The clinical efficacy,remission of clinical symptoms,adverse reactions were compared between the two groups.Results The total curative effective rate of the observation group(96.00%)was higher than that of control group (82.00%),and the difference was statistically significant(P＜0.05).The respiratory rate,times of cough,sputum volume in observation group[(22.82±5.61)times/min,(5.72±1.86)times,(14.28±3.57)ml]were less than those in control group[(25.69±6.58)times/min,(7.13±2.04)times,(16.74±3.93)ml],and the differences were statistically significant(P＜0.05).There was no statistical difference in the incidence of adverse reactions between the patients in two groups (P＞0.05).ConclusionEucalyptol Linonene Pinene Enteric Soft Capsules in treatment of cough caused by postnasal drip syndrome can increase curative effects and improve clinical symptoms of patients,which has higher safety. 2018 Vol. 25 (27): 68-70 [Abstract] ( 152 ) HTML (36 KB)  PDF  (0 KB)  ( 25 ) 71 Effect and safety of inhalation of general anesthesia for fundus examina‐tion in preterm infants at different gestational ages WENG Jian-sen;XIE Hai-hang Objective To observe the effect and safety of inhalation of general anesthesia for fundus examination in preterm infants at different gestational ages.Methods A total of 62 preterm infants with retinopathy with corrected gestational age of 33-64 weeks from October 2016 to October 2017 treated in the ophthalmology clinic of our hospital were selected as objects.They were divided into group A and group B according to the different gestational age,with 31 cases in each group.The corrected gestational age of preterm infants in group A was 33-44 weeks,and the corrected gestational age of preterm infants in group B was over 44-63 weeks.In the two groups of children with retinopathy,the fundus examination was performed with inhalation of 6%of Sevoflurane.The body motion stop time was used as the induction time of anesthesia,and the concentration of Sevoflurane anesthesia was given after 2 times of induction time.The initial concentration of maintenance concentration of the two groups was 3%,and the adjusted range of the inhalation concentration was 0.5%.The duration of anesthesia,the time of anesthesia induction,and the awakening time after the cessation of anesthesia were recorded in the two groups,and the adverse reactions such as vomiting and cough were observed during the induction and maintenance of anesthesia in the two groups.After 1 h of the end of fundus examination,whether there were vomiting and cough during drinking and feeding during in the two groups were observed.Results The average maintenance concentration of group A was(2.4±0.5)%,which was significantly lower than that of group B accounting for(3.1±0.7)%,and the difference was statistically significant(P＜0.05).The average anesthesia maintenance time and the average anesthesia waking time in group A was(493.7±104.5)s and(352.6±157.3)s respectively,the group B was(492.8±114.6)s and(367.1±155.3)s respectively,and there were no statistically significant differences in average anesthesia maintenance time and the average anesthesia waking time between two groups(P＞0.05).The average anesthesia induction time of the group A was(56.4±13.1)s,which was significantly shorter than that in the group B accounting for(75.6±13.2)s,and the difference was statistically significant(P＜0.05).Conclusion In order to ensure the safety of the children,Sevoflurane inhalation anesthesia in preterm infants should be strictly controlled according to the conditions of different gestational ages and the needs of the children. 2018 Vol. 25 (27): 71-73 [Abstract] ( 137 ) HTML (34 KB)  PDF  (0 KB)  ( 19 ) 74 Comparison of analgesic effect and safety between Dezocine and Penta‐zocine combined with Ropivacaine after cesarean section LIU Li-ying;LIU Yu-ming; SHU Jian;LI Xiao-lan;CHEN Chun-lian Objective To compare the analgesic effect and safety between Dezocine and Pentazocine combined with Ropivacaine after cesarean section.Methods A total of 100 pregnant women with the full term singleton for the first cesarean section under spinal and spinal anesthesia from March 2017 to March 2018 in Ganzhou Maternal and Child Health Hospital were selected as objects and the patient-controlled analgesia(PCA)was given after the operation.They were randomly divided into group A and group B,with 50 cases in each group.Group A was given the Dezocine combined with Ropivacaine,and Group B was given the Pentazocine combined with Ropivacaine.The analgesic effect and the number of PCA pressed at 2,6,12,24,48 h after surgery,and the total rate of adverse reactions were compared between two groups.Results There were no significant differences in numerical rating scale(NRS)scores and the number of effective PCA compressions at 2,6,12,24,and 48 h after surgery between two groups (P＞0.05).There was no significant difference in the incidence of adverse reactions between two groups(P＞0.05).Conclusion The analgesic effect of Dezocine and Pentazocine is similar,with fewer adverse reactions and effective safety. 2018 Vol. 25 (27): 74-76 [Abstract] ( 128 ) HTML (35 KB)  PDF  (0 KB)  ( 20 ) 77 Application effect of ultrasound-guided thoracic paravertebral nerve block in minimally invasive percutaneous nephrolithotomy ZHANG You-chun;OUYANG Ai-ping Objective To explore the application effect of ultrasound-guided thoracic paravertebral nerve block in minimally invasive percutaneous nephrolithotomy.Methods A total of 60 cases of patients who undergone minimally invasive percutaneous nephrolithotomy in our hospital from February 2017 to February 2018 were selected as the research subjects,and they were divide into the control group(30 cases)and the study group(30 cases)according to the random number table method.The control group was given epidural anesthesia,and the study group was treated with ultrasound-guided thoracic paravertebral block anesthesia.The anesthetic effect,heart rate (HR),systolic pressure(SBP)and diastolic pressure(DBP)before anesthesia(T0),5 min after anesthesia(T1),start of surgery(T2),and end of surgery(T3),and postoperative adverse reactions were compared and analyzed between two groups.Results The onset time,anesthetic time and operative time of the study group were lower than those of the control group,and the differences were statistically significant(P＜0.05).The SBP and DBP at T1time point in the study group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The total rate of adverse reactions in the study group was 3.33%,which was significantly lower than that of the control group (23.33%),and the difference was statistically significant(P＜0.05).Conclusion Ultrasound guided thoracic paravertebral nerve block is effective in minimally invasive percutaneous nephrolithotomy,with fewer adverse reactions and faster postoperative recovery,which can be widely applied in clinical practice. 2018 Vol. 25 (27): 77-79 [Abstract] ( 120 ) HTML (36 KB)  PDF  (0 KB)  ( 21 ) 80 Application of epidural combined with general anesthesia in gynecological laparoscopic surgery YANG Yan;ZHU Zhi-dong;LI Wei-bin;YU Su-ting Objective To explore the effect of epidural combined with general anesthesia in gynecological laparoscopic surgery.Methods A total of 62 cases of patients who underwent gynecological laparoscopic surgery in our hospital from February 2017 to February 2018 were selected as objects.According to the principle of random equality,they were divided into the control group (n=31)and the study group (n=31).The control group was given general anesthesia,and the study group was given epidural combined with general anesthesia.Hemodynamic indexes,anesthesia recovery and postoperative restlessness were compared between two groups.Results The heart rate after induction of anesthesia in two groups were lower than those before induction,and the differences were statistically significant(P＜0.05).The heart rate after 10 min of pneumoperitoneum and the operation in the study group were lower than those before anesthesia induction,the heart rate after 10 min of pneumoperitoneum and the operation in the control group were higher than those before anesthesia induction,and the differences were statistically significant(P＜0.05).The heart rate after induction of anesthesia in the study group was higher than that in the control group,the heart rate after 10 min of pneumoperitoneum and the operation were lower than those in the control group,and the differences were statistically significant(P＜0.05).The mean arterial pressure after induction of anesthesia and after 10 min of pneumoperitoneum in two groups were lower than those before anesthesia induction,and the differences were statistically significant(P＜0.05).The mean arterial pressure after the operation in the study group was lower than that before induction,the mean arterial pressure after the operation in the control group was higher than that before induction,and the differences were statistically significant(P＜0.05).The mean arterial pressure after induction of anesthesia in the study group was higher than that in the control group,the mean arterial pressure after 10 min of pneumoperitoneum and the operation were lower than those in the control group,and the differences were statistically significant(P＜0.05).The operation time,recovery time and extubation time of the study group were shorter than those of the control group,and the differences were statistically significant(P＜0.05).There was no significant difference in the incidence of restlessness between the study group(3.23%[1/31])and the control group(6.45%[2/31])(P＞0.05).ConclusionThe application of epidural combined with general anesthesia in gynecological laparoscopic surgery can stabilize the hemodynamics and improve the recovery effect of anesthesia,which is worthy of clinical promotion and application. 2018 Vol. 25 (27): 80-82 [Abstract] ( 117 ) HTML (34 KB)  PDF  (0 KB)  ( 29 ) 83 Anesthetic effect of ultrasound-guided brachial plexus block in upper limb surgery JIANG Ying;YE Xian-rui;HUANG Dan-hui Objective To observe the anesthetic effect of ultrasound-guided brachial plexus block in upper limb surgery.Methods A total of 83 patients with upper limb surgery who were admitted to our hospital from February 2015 to February 2016 were selected as the research subjects,and they were divided into the traditional group (41 cases)and the ultrasound group (42 cases)according to the random number table method.Local anesthesia was performed in both groups.The traditional group was given traditional anatomical puncture positioning,and the ultrasound group was given ultrasound-guided puncture positioning.The anesthesia operation completion time,sensory block onset time,exercise block onset time,visual analogue scale (VAS),cases of postoperative anesthetic drugs,rate of adverse reaction and block situation of branch innervation area were compared between the two groups.Results The time of anesthesia operation completion in the ultrasound group was significantly longer than that in the traditional group,the onset time of sensory and motor block were significantly shorter than those in the traditional group,VAS score and the incidence of adverse reactions were significantly lower than those in the traditional group,and the differences were statistically significant(P＜0.05).There was no statistically significant difference in the rate of receiving postoperative analgesic drugs between the two groups(P＞0.05).The degree of ulnar nerve block in the ultrasound group was lighter than that in the traditional group,and the difference was statistically significant(P＜0.05).There was no significant difference in the median nerve and radial nerve block between the two groups(P＞0.05).Conclusion Ultrasound-guided brachial plexus block requires longer time than traditional anatomical positioning,but the onset time of anesthesia is shorter,which is better for ulnar nerve block.Moreover,the operation is simpler,the adverse reactions are less,and the cost is lower.It can improve the effectiveness,accuracy and safety of anesthesia and has a higher clinical promotion value. 2018 Vol. 25 (27): 83-85转97 [Abstract] ( 131 ) HTML (36 KB)  PDF  (0 KB)  ( 26 ) 86 The value of contrast-enhanced ultrasound in the diagnosis of intrahepatic focal lesions WANG Hao;SONG Yan;DENG Ya-qin;Gan Li-Hong Objective To evaluate the value of contrast-enhanced ultrasound(CEUS)compared with conventional Ultrasound (US)and enhanced CT (CECT)in the diagnosis and differential diagnosis of atypical hepatic focal lesions(FLL).Methods In our hospital from January 2014 to December 2017,36 patients with 40 FLL were respectively given US,CEUS and CECT examination,using pathological results as the gold standard,the test results of three groups were compared with pathological findings of test sensitivity,specificity,accuracy three groups was compared.Results With pathological results as the gold standard of US in the diagnosis of FLL the sensitivity,specificity and accuracy were 63.3%(19/30),60.0%(6/10),62.5%(25/40);CEUS diagnosis of FLL the sensitivity,specificity and accuracy were 93.3%(28/30),80.0%(8/10),90.0%(36/40).The sensitivity,specificity and accuracy of CECT in the diagnosis of FLL were 90.0%(27/30),80.0%(8/10),and 87.5%(35/40),respectively.The sensitivity and accuracy of CEUS and CECT in the diagnosis of atypical FLL were significantly better than those of US(P＜0.05）.There was no significant difference between CEUS and CECT in the diagnosis of FLL(P＞0.05）.Conclusion CEUS and CECT have high clinical value in the differential diagnosis of atypical FLLand benign and malignant lesions,which are all higher than those of US. 2018 Vol. 25 (27): 86-88 [Abstract] ( 98 ) HTML (36 KB)  PDF  (0 KB)  ( 21 ) 89 Observation of color Doppler ultrasonography on the changes of liver hemodynamics，gallbladder wall，and liver function in clinical application YU Wen-hua;HE Zhen;CHENG Ying;FANG Nian-fu Objective To investigate and analyze the changes of liver hemodynamics,gallbladder wall and liver function of patients with diffuse liver diseases observed by color Doppler ultrasonography.Methods A total of 90 patients with diffuse liver diseases who were hospitalized in our hospital from January 2016 to December 2017 were selected as research objects.They were divided into fatty liver disease (FLD)group,chronic hepatitis group,and liver cirrhosis group according to the types of liver diseases.Another group of 30 healthy people was recruited as normal control.The inner diameter of hepatic portal vein,pulse ratio (PR),the blood flow frequency spectrum of right and middle hepatic veins,resistance index (RI)of hepatic artery,and the thickness and smoothness of gallbladder wall of diffuse liver diseases groups observed by color Doppler ultrasonography were comparatively analyzed.Results The changes of RI of hepatic artery,abnormal spectrum of hepatic veins,the inner diameter of hepatic portal vein,PR,and gallbladder wall in mild to moderate and moderate patients in the FLD group were not in great difference from those in the normal control group (P＞0.05）,while the differences of the above indicators between severe FLD patients and people in normal control group were statistically significant(P＜0.05） except for the changes of gallbladder wall(P＞0.05）.The changes of RI in hepatic artery,spectromorphology of hepatic veins,the inner diameter of hepatic portal vein,PR,and gallbladder wall in the chronic hepatitis group and the liver cirrhosis group were both significant different from those in the normal control group (P＜0.05）.Conclusion For patients with diffuse liver diseases,application of color Doppler ultrasonography can clearly observe the liver hemodynamics,gallbladder wall morphology,the inner diameter of portal vein,PR,RI of hepatic artery,and spectromorphology of hepatic veins,which can be used as a clinical diagnostic indicator of diffuse liver diseases,and has great clinical promotion value. 2018 Vol. 25 (27): 89-91 [Abstract] ( 106 ) HTML (37 KB)  PDF  (0 KB)  ( 18 ) 92 Clinical study of Multi-slice spiral CT and ultrasound in the diagnosis of female pelvic cystic masses YE Jia-run;WANG Chun-ling Objective To explore the clinical value of multi-row spiral CT(MSCT)and ultrasound in the diagnosis of female pelvic cystic mass.Methods 80 cases of female pelvic cystic mass in our hospital from April 2017 to April 2018 were selected as the research subjects.All of them were detected by MSCT and ultrasound,and the results of two detection methods were compared.Results In 80 cases of pelvic cystic mass,the accuracy rate of the tumor tissue after ultrasound was 60%,64.44%,58.33%and 61.11%after operation and histopathology.The corresponding value of location accuracy was 40.00%,57.77%,58.33%,55.56%and the sensitivity was 62.50%.After MSCT detection,the patient diagnosis results showed that the correct rate was 80.00%,95.56%,100.00%and 94.44%,the corresponding accuracy of location accuracy was 100.00%,91.11%，83.33%,88.89%,and sensitivity was 95.00%.Comparing the data between the two methods,the accuracy and sensitivity of MSCT were better than that in the corresponding values of the ultrasonic detection,and the difference was statistically significant(P＜0.05）.Conclusion For female patients with pelvic cystic masses take more row MSCT in the diagnosis,the lesions also is better than that of ultrasonic testing organization to identify and locate accurate rate,and high sensitivity,for patients diagnosed with good clinical value,is worth promoting clinically. 2018 Vol. 25 (27): 92-94 [Abstract] ( 111 ) HTML (32 KB)  PDF  (0 KB)  ( 22 ) 95 Comparision of application value of B ultrasound imaging technology and X-ray imaging technology in the diagnosis of hydronephrosis YE Xiao-ming;JIANG Rong-bin Objective To investigate the diagnostic efficacy of B ultrasound imaging technology and X-ray imaging technology in hydronephrosis.Methods From January 2017 to March 2018,93 cases of hydronephrosis were randomly selected in our hospital.All patients were diagnosed by clinical observation and urography.They were subjected to B ultrasound imaging technology and X respectively.Line imaging technology diagnosis,observation and comparison of the two diagnostic methods of disease detection rate and cause of judgment accuracy.Results The detection rate of renal sinus separation≤1.0 cm and renal sinus separation 1.1-2.0 cm were respectively 96.97%and 94.87%in B-mode ultrasonography,which were higher than X-ray imaging techniques 75.78%and 79.49% (P＜0.05）.The positive detection rate of sinus≥2.1 cm in imaging techniques and X-ray imaging techniques was 95.24%and 90.48%,respectively.There was no significant difference between the two methods (P＞0.05）.In terms of etiological diagnosis,B-ultrasound imaging technology was used to expand the ureters.The detection rates of kidney stones and ureteral stones were 93.10%,94.44%,and 92.86%,respectively,which were higher than those in the X-ray imaging techniques (86.21%,86.11%,and 85.71%),but there was no significant difference between the two groups(P＞0.05）.Conclusion In the process of diagnosis of hydronephrosis diseases,B-mode ultrasound imaging technology plays an important role.Its detection rate is high and its image features are obvious.It provides an effective basis for follow-up treatment,but it must be done in conjunction with the actual situation of patients to do a good job in return visits,improve diagnostic accuracy. 2018 Vol. 25 (27): 95-97 [Abstract] ( 94 ) HTML (31 KB)  PDF  (0 KB)  ( 26 ) 98 Diagnosis and clinical application of CT perfusion imaging in hepatocellular carcinoma CHENG Liang Objective To analyze the clinical value of CT perfusion imaging (CTP)in the diagnosis of hepatocellular carcinoma （HCC）.Methods A total of 74 patients with HCC who were treated by surgery and pathology from August 2015 to August 2017 were selected and divided into control group and research group according to the actual preoperative inspection methods，37 cases in each group.The control group was received routine CT scan before operation,and the study group was received CTP before operation.The coincidence rate of blood volume,perfusion volume,operation time,incident rate,misdiagnosis rate,missed diagnosis rate,preoperative examination results and postoperative pathological findings were compared.Results The patients in the study group during the inspection of blood volume was lower than that in the control group,the perfusion rate was higher than that in the control group,operation time was shorter than that in the control group (P＜0.05）.Dispute incident rate was only 2.7%,lesser than that in the control group(13.5%)(P＜0.05）.The rate of misdiagnosis and missed diagnosis rate was lower than that in the control group (P＜0.05）;preoperative examination results and postoperative pathology results coincidence rate was reached 94.6%,higher than 70.3%of the control group,the differences were statistically significant(P＜0.05）.Conclusion Using CTP to diagnose the condition of HCC can shorten the operation time,reduce the rate of misdiagnosis and missed diagnosis,reduce the disputes caused by it,and improve the accuracy of diagnosis of hepatocellular carcinoma. 2018 Vol. 25 (27): 98-100 [Abstract] ( 108 ) HTML (33 KB)  PDF  (0 KB)  ( 18 ) 101 Application value of stress dynamic CT myocardial perfusion imaging combined with coronary CT angiography in diagnosis of ischemic coronary artery disease WANG Su-yan Objective To investigate the application value of stress dynamic CT myocardial perfusion imaging (CTMPI)combined with coronary CT angiography (CCTA)in diagnosing myocardial ischemia of coronary heart disease.Methods Forty patients with ischemic coronary artery diseases who were admitted to our hospital from January to December 2017 were selected as the study subjects.They were examined by CCTA alone and stress dynamic CT-MPI combined with CCTA.The former was classified into control group,and the latter was categorized into observation group,20 cases in each group.The dosage of contrast agent and radiation dose,the proportion of luminal stenosis due to plaque,plaque length,and the diagnostic rates of the two groups were compared.Results Compared with the control group,the dosage of contrast agent in the observation group was lesser with a significant difference(P＜0.05）.The radiation dose was lower(P＜0.05）.The proportion of luminal stenosis due to plaque was higher than that in the control group with a significant difference (P＜0.05）.The plaque in the observation group was greatly longer than that of the control group (P＜0.05）.The diagnostic rate of the observation group was significantly higher than that of the control group with a statistical difference (P＜0.05）.Conclusion For patients with myocardial ischemia of coronary heart disease,application of stress dynamic CT-MPI and CCTA can effectively confirm the coronary artery stenosis and plaque lesions in a small dosage of contrast agent,a low radiation dose,and greatly increase the clinical diagnosis rate. 2018 Vol. 25 (27): 101-103 [Abstract] ( 95 ) HTML (36 KB)  PDF  (0 KB)  ( 24 ) 104 Effect analysis of Deferoxamine Mesylate on hypertensive intracerebral hemorrhage XIONG Cheng-ying Objective To analyze the effect of Deferoxamine Mesylate on hypertensive intracerebral hemorrhage.Methods A total of 113 patients with hypertensive intracerebral hemorrhage treated in our hospital from January to December 2017 were selected as study objects and they were divided into two groups according to the random digital table method,which were the control group(53 cases)and the study group(60 cases).The control group received the routine treatment.The study group was treated with Deferoxamine Mesylate on the basis of routine treatment.The relative edema volume,relative hematoma volume and prognosis at different time points(7,14 days after treatment)were analyzed.Results At 7,14 days after treatment,the relative edema volume and relative hematoma volume in the study group were less than those in the control group,the differences were statistically significant(P＜0.05).At 7,14 days after treatment,the NIHSS scores of the study group were lower than those of the control group (P＜0.05).And the relative edema volume and relative blood of 14 days after treatment in the study group were less than those of 7 days after treatment,the differences were statistically significant(P＜0.05).The NASS score of 14 days after treatment in the study group and the control group were lower than those of 7 d after treatment,and the differences were statistically significant(P＜0.05).Conclusion The application of Deferoxamine Mesylate in the treatment of hypertensive intracerebral hemorrhage is significant.It can not only reduce the volume of relative hematoma,but also effectively reduce the volume of relative edema,and help to promote the recovery of nerve function and the prognosis is good. 2018 Vol. 25 (27): 104-106转113 [Abstract] ( 111 ) HTML (37 KB)  PDF  (0 KB)  ( 23 ) 107 Clinical effect observation of Glimepiride in the treatment of type 2 diabetes patients with secondary failure of traditional Sulfonylureas KE Rui-qiong;FANG Xiang-nan;WANG Yang;QIN Yong-zhang;XIAO Li-xia;LYU Wei-ming Objective To observe the clinical effect of application of Glimepiride in the treatment of Type 2 diabetes patients with secondary failure of traditional Sulfonylureas.Methods Altogether 70 type 2 diabetes patients with secondary failure who were treated with traditional Sulfonylureas in our hospital from March 2015 to September 2017 were involved as the subjects of this research,and they were divided into study group(35 cases)and control group(35 cases).After 2-week discontinuation of the original Sulfonylureas,patients in study group were given Glimepiride and the patients in control group were treated with Repaglinide,patients were treated for 24 weeks.Changes in fasting blood glucose,2 h postprandial blood glucose,fasting insulin,glycosylated hemoglobin,body mass index(BMI),insulin resistance,islet function and adverse reactions were observed before and after treatment in the two groups.ResultsThe fasting blood glucose,2 h postprandial blood glucose,glycated hemoglobin and insulin resistance of two groups after treatment were lower than those before treatment,while the fasting insulin of two groups was higher than before treatment,with statistically significant differences(P＜0.05).There were no statistically significant difference in islet β-cell function and BMI between the two groups before and after treatment(P＞0.05).The fasting blood glucose,glycated hemoglobin and insulin resistance of study group were lower than those of the control group,with statistically significant differences(P＜0.05).There were no serious adverse reactions in the two groups.Conclusion Application of Glimepiride in the treatment of patients with secondary failure of type 2 diabetes who previously underwent traditional Sulfonylurea treatment,can further improve patients'blood glucose and insulin resistance without increase of adverse reactions.Glimepiride can be used as an effective scheme in the treatment of Type 2 diabetes patients with secondary. 2018 Vol. 25 (27): 107-109 [Abstract] ( 112 ) HTML (39 KB)  PDF  (0 KB)  ( 20 ) 110 Effect comparative analysis of the effect of single using Flunarizine and using Flunarizine combined with Xuesetong in the treatment of elderly migraine patients ZHANG Li;YONG Xue-wei Objective To study the comparative analysis of the efficacy of single using Flunarizine and using Flunarizine combined with Xuesetong in the treatment of elderly migraine patients and to provide effective treatment for the treatment and recovery of senile migraine.Methods A total of 80 cases of elderly migraine patients receiving treatment in our hospital from August 2015 to December 2016 were selected as the study subjects.They were divided into control group and study group of 40 patients with a random number table method.The patients in the control group were treated with Flunarizine,and the study group were treated with Flunarizine combined with Xuesetong.The treatment effect,adverse reaction after treatment and the change of headache symptoms before and after treatment(including headache score,duration and number of attacks)were compared.Results The total effective rate of treatment in the study group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant(P＜0.05).In the control group and the study group,the scores of headache after treatment were lower than before treatment,and the differences were statistically significant(P＜0.05).The duration of migraine after treatment in the control group and the study group were lower than those of the group before treatment,and the differences were statistically significant(P＜0.0.5).The number of migraine attacks in the control group and the study group were less than those of the group before treatment,and the differences were statistically significant(P＜0.05).Before treatment,there were no statistically significant difference in headache score,duration and number of attacks between the two groups(P＞0.05).In the study group,the scores of headache after treatment was lower than that in the control group,and the difference was statistically significant(P＜0.05).The duration of migraine after treatment in the study group were lower than that in the control group,and the difference was statistically significant(P＜0.05).The number of migraine attacks in the study group were less than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion The effect of Flunarizine on the treatment of senile migraine was significantly better than that of the patients treated with Flunarizine alone.And there was no obvious adverse reaction and it has very good therapeutic effect. 2018 Vol. 25 (27): 110-113 [Abstract] ( 113 ) HTML (37 KB)  PDF  (0 KB)  ( 24 ) 114 Effect of application of combination of Vitamin C and Ranitidine Hydrochlorlde Capsules in the treatment of recurrent oral ulcer LI Min Objective To explore the clinical effect of application of combination of Vitamin C and Ranitidine Hydrochlorlde Capsules in the treatment of recurrent oral ulcer(ROU)and its influence on the patients'immune function.Methods Altogether 140 cases with ROU who were treated in our hospital from April 2016 to April 2017 were selected as the subjects of this research,and divided into the control group (70 cases)and the observation group (70 cases)according to the random number method.Patients in the control group were treated with Vitamin C,while the patients in the observation group were treated with the combination of Vitamin C and Ranitidine Hydrochlorlde Capsules.The total effective rate and the changes of various indexes of the two groups,such as T lymphocyte positive (CD3+),auxiliary T lymphocyte positive(CD4+),suppressor/cytotoxic T lymphocyte positive(CD8+)and CD4+/CD8+were compared.Results The total effective rate of the observation group was significantly higher than that of the control group,with statistically significant difference (P＜0.05).The post-treatment CD3+level of the observation group was significantly higher than that of the control group,with statistically significant difference (P＜0.05).There was nostatistically significant difference in CD4+between the observation group and the control group(P＞0.05).The CD8+level of the observation group was significantly lower than that of the control group,with statistically significant difference (P＜0.05).The CD4+/CD8+level of the observation group was significantly higher than that of the control group,with statistically significant difference (P＜0.05).Conclusion Application of combination of Vitamin C and Ranitidine Hydrochlorlde Capsules achieves significant effect in the treatment of ROU,conduciveness to ulcer healing and improvement of patients'immune function,which is worth popularizing in clinical practice. 2018 Vol. 25 (27): 114-116 [Abstract] ( 129 ) HTML (38 KB)  PDF  (0 KB)  ( 17 ) 117 Effect of Salmeterol and Fluticasone Propionate Aerosol combined with Ipratropium Bromide on serum levels of CRP,IgE and EOS in patients with asthma and chronic obstructive pulmonary disease overlap syndrome WANG Wen-juan;HUANG Li-nian;WU Jing;MENG Nan Objective To analyze the effect of Salmeterol and Fluticasone Propionate Aerosol and Ipratropium Bromide on serum C reactive protein(CRP),immunoglobulin E(IgE),the percentage of eosinophils(EOS)level in patients with asthma and chronic obstructive pulmonary disease overlap syndrome (ACOS).Methods A Total of 80 cases of ACOS patients who treated in our hospital from January 2016 to January 2018 were selected as subjects.According to the digital random method,they were randomly divided into control group and experimental group,with 40 cases in each group.The control group was treated with Salmeterol and Fluticasone Propionate Aerosol,and the experimental group was treated with Salmeterol and Fluticasone Propionate Aerosol combined with Ipratropium Bromide.The levels of serum CRP,IgE and EOS,the clinical efficacy and respiratory function improvement were observed and analyzed before and after treatment.Results The total effective rate of clinical treatment in the experimental group was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).The levels of serum CRP,IgE and EOS in the experimental group were significantly lower than those in the control group,the differences were statistically significant(P＜0.05).The one second forced breathing volume(FEV1),FEV1/forced vital capacity(FVC),predictive value of FEV1after treatment were significantly higher in the experimental group than those in the control group,the differences were statistically significant(P＜0.05).Conclusion In the treatment of ACOS patients,the treatment of Salmeterol and Fluticasone Propionate Aerosol combined with Ipratropium Bromide can achieve an ideal effect.It can significantly improve the level of serum CRP,IgE,EOS and pulmonary function,and is worthy of clinical promotion. 2018 Vol. 25 (27): 117-119 [Abstract] ( 97 ) HTML (37 KB)  PDF  (0 KB)  ( 21 ) 120 Effect of Racecadotril Granules combined with Ribavirin in the treatment of infantile Rotavirus enteritis ZHANG Yi Objective To explore the effect of Racecadotril Granules combined with Ribavirin in the treatment of infantile Rotavirus enteritis.Methods A total of 80 children with Rotavirus enteritis treated in our hospital from January to December 2016 were selected as the research subjects,and divided into the control group and the observation group according to the random number table method,with 40 cases in each group.The children in the control group were treated with Ribavirin,and the children in the observation group were treated with Racecadotril Granules on the basis of the control group.After treatment,the clinical effects of the two groups were observed and compared.Results The fever time,diarrhea time,antiemetic time and treatment time in the observation group were shorter than those in the control group,the differences between the two groups of clinical symptoms improvement time and treatment time were statistically significant(P＜0.05).The negative rate of Rotavirus in the observation group (87.5%)was higher than that in the control group (45.0%),and the difference was statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion Racecadotril Granules combined with Ribavirin for the treatment of Rotavirus enteritis in children has a good clinical effect.It is better than the only child with Ribavirin treatment for children with Rotavirus enteritis,and it is highly safe and worthy of clinical application. 2018 Vol. 25 (27): 120-122 [Abstract] ( 111 ) HTML (33 KB)  PDF  (0 KB)  ( 24 ) 123 Diagnostic values of interleukin-22 and four items detection of liver fibrosis on liver fibrosis degree YANG Jie-wen;HONG Jun-na;FANG Jia;XUE Feng;JIN Wei-xun Objective To observe the diagnostic values of interleukin-22 (IL-22)and four items detection of liver fibrosis on the liver fibrosis degree.Methods A tatal of 90 cases of patients diagnosed with liver fibrosis by needle biopsy in Tangxia Hospital of Dongguan City from December 2013 to December 2017 were selected as the subjects.The levels of serum IL-22 and four items of liver fibrosis[hyaluronic acid(HA),collagen typeⅣ (C-Ⅳ),procollagenⅢN-terminal peptide(PⅢNP),laminin(LN)]were compared in patients with liver fibrosis at different pathological stages,and the correlation between the above serological indexes and the liver fibrosis degree and its diagnostic values on the liver fibrosis degree were analyzed.Results The serum levels of IL-22,HA,C-Ⅳ,PⅢNP and LN were increased with the severity of liver fibrosis(P＜0.05).Spearman correlation analysis showed that serum levels of IL-22,HA,C-Ⅳ,PⅢNP and LN were significantly and positively correlated with the liver fibrosis degree (r=0.634,0.612,0.563,0.551,0.547,P＜0.05).The diagnostic accuracy of liver fibrosis degree was 84.68%by combined diagnosis of serum IL-22,HA,C- Ⅳ,PⅢNP and LN,which was significantly higher than that by single detection with 77.59% (P＜0.05).Conclusion The levels of serum IL-22 and four items of liver fibrosis are increased with the severity of liver fibrosis,and there is a significant positive correlation with liver fibrosis degree.The combined detection of above indexes can significantly improve the diagnostic accuracy of liver fibrosis degree. 2018 Vol. 25 (27): 123-125转135 [Abstract] ( 116 ) HTML (39 KB)  PDF  (0 KB)  ( 27 ) 126 Study of changes of coagulation function indicators in neonates in Bao'an District,Shenzhen City WANG Jin-sheng;HUANG Guang-yong;ZOU Wei-yang;HUANG Yu-jia Objective To explore five reference intervals and the change rule of coagulation function in neonates in Bao'an District,Shenzhen City.Methods A total of 250 neonates born in our Department of Obstetrics from June 2017 to January 2018 were selected as the subjects.According to whether the gestational cycle reaching 37 weeks,the neonates were divided into full-term group and preterm group,with 125 cases in each group.The prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),fibrinogen(Fib)level and platelet count(PLT)within 1 day after birth in the full-term group and the preterm group were compared,as well as the levels of the above-mentioned indicators of newborns at different time such as 1～＜3,3～＜7,7～＜14 and 14～＜21 days.Results The postpartum PT,APTT and TT in the preterm group were significantly higher than those in the full-term group(P＜0.05),while the levels of FIB and PLT were significantly lower than those in the full-term group (P＜0.05).The levels of PT,APTT and TT of neonates on 14～＜21 days after birth were significantly lower than those on 1～＜3 days(P＜0.05),while the levels of FIB and PLT of neonates on 14～＜21 days after birth were significantly higher than those on 1～＜3 days(P＜0.05).Conclusion The distribution of neonatal coagulation function indicators in this region has its own characteristics.The levels of PT,APTT and TT of preterm infants are longer than those of full-term infants,while the levels of FIB and PLT are lower. 2018 Vol. 25 (27): 126-128 [Abstract] ( 118 ) HTML (33 KB)  PDF  (0 KB)  ( 24 ) 129 Analysis of clinical distribution and drug resistance of Acinetobacter baumannii infection in 228 strains WANG Po Objective To analyze the clinical infection and drug resistance of Acinetobacter baumannii in order to provide a theoretical basis for clinical rational drug use.Methods A total of 228 strains of Acinetobacter baumannii isolated of hospitalized patients from January 2015 to December 2017 were selected for study.Vitek 2 compact automatic microbial identification and analysis system was used to identify strains,The specimens,distribution of departments,and drug resistance of Acinetobacter baumannii were analyzed.All data were statistically analyzed using WHONET5.4,a drug resistance monitoring software.Results A total of 228 strains of Acinetobacter baumannii were isolated.The detection rate was high in sputum specimens,wound secretions and urine,there were 154 strains accounted for 67.54%,31 strains for 13.60%,and 14 strains for 6.14%.In the distribution of the department,there were 108(47.37%)strains in the intensive care unit,followed by 36 (15.79%)strains in the respiratory medicine department.Acinetobacter baumannii had the lowest drug resistance to Minocycline and Cefoperazone/Sulbactam,but for other antimicrobial agents,the drug resistance rate was over 60%.Conclusion The detection rate of Acinetobacter baumannii is high,and the drug resistance is increasing year by year.It should be highly noted that standard continuous monitoring of Acinetobacter baumannii and the analysis of its drug resistance are performed. 2018 Vol. 25 (27): 129-131 [Abstract] ( 107 ) HTML (32 KB)  PDF  (0 KB)  ( 21 ) 132 Investigation on the off-label use of neurotrophic auxiliary drugs GUAN Xiao-min;GE Jian-bin Objective To understand the current status of the off-label use of neurotrophic auxiliary drugs in our hospital,analyze the possible risks of drug use,and propose corresponding solutions to provide reference for the standardized management of neuropharmacologic auxiliary drugs.Methods A total of 360 prescriptions of inpatients from January to December in 2017 in our hospital were randomly selected.Statistical results of the off-label use of neurotrophic auxiliary drugs in our hospital were summarized and analyzed referred to the latest edition of the pharmaceuticals,guidelines for the use of drugs at home and abroad,and the latest evidence-based medical evidence.Results Out of 360 prescriptions,246 prescriptions for the off-label drug use accounted for 68.3%of the total prescriptions.The most common form of the off-label drug use was hyperindicated drug use,followed by over-dosage and over-treatment drug use,respectively accounting for 82.9%,26.0%,and 23.6%of the total number of instructions.The ratio of off-label drug use,Edaravone,Oxiracetam and Flunarizine Hydrochloride Capsules respectively was 69.3%,97.6%,and 100%.In the process of off-label drug use,the highest incidence of adverse reactions was Oxiracetam Injection(27.8%),followed by Piracetam(21.4%)and Edaravone Injection(21.1%).Conclusion The clinical practice of the off-label use of neurotrophic auxiliary drugs is very common,but it has certain rationality and cannot be generalized.Clinicians should rationally use drugs on the basis of drug instructions.Pharmacy personnel should actively cooperate with relevant departments to strengthen drug supervision and regulate the behavior of the off-label drug use. 2018 Vol. 25 (27): 132-135 [Abstract] ( 120 ) HTML (39 KB)  PDF  (0 KB)  ( 20 ) 136 Effect of family care degree on psychological resilience and depression in the puerpera with postpartum depression ZHANG Jin-qiu Objective To explore the effect of family care degree on psychological resilience and depression in the puerpera with postpartum depression.Methods A total of 2000 puerpera in the department of obstetrics of our hospital from January to December 2017 were selected as objects.The Edinburgh postnatal depression screening scale(EPDS),family care index(APGAR),the Connor-avidson resilience scale(CD-RISC),and Hamilton depression scale(HAMD)were used to screen postpartum depression women and non-postpartum depression women.The differences between family care,psychological resilience and depression were compared between two groups.Pearson correlation analysis was used to analyze the correlation between family care,psychological resilience and depression.The mediating effect analysis method was used to analyze the mediating effect of family care.Results Among 2000 puerperas,the puerpera with postpartum depression were 286,whose detection rate was 14.3%,and the puerpera without postpartum depression were 1714.The APGAR score ([4.64±1.15]points)and CD-RISC total score ([52.83±7.37]points)in postpartum depression women were significantly lower than those in non-postpartum depression women([8.16±1.49]points,[83.56±8.42]points),HAMD total score ([19.35±4.29]points)was significantly higher than that in non-postpartum depression women([6.29±1.51]points),and the differences were statistically significant(P＜0.01).The results of correlation analysis showed that psychological resilience was positively correlated with family care(r=0.514,P＜0.01),psychological resilience was negatively correlated with depression (r=-0.622,P＜0.01),and family care was negatively correlated with depression (r=-0.638,P＜0.01).The results of regression analysis showed that psychological resilience and family care had significant negative predictive effect on depression (β=-0.894,P＜0.01;β=-0.628,P＜0.01).The value of mediating effect from psychological resilience to depression was 0.263,and the ratio of mediating effect to total effect was 0.294.Conclusion Family care degree plays a partial mediating role between psychological resilience and depression.To improve family care degree helps to promote the level of psychological resilience and improves depression condition. 2018 Vol. 25 (27): 136-139 [Abstract] ( 101 ) HTML (41 KB)  PDF  (0 KB)  ( 25 ) 140 Analysis the role of risk management in preventing medical disputes and complaints in outpatient and emergency departments LU Chang-bin;CHI Hui;HAN Qing-ping Objective To analyze the role of risk management in preventing medical disputes and complaints in outpatient and emergency departments.Methods Data of outpatient and emergency departments of Zhongshan Hospital Affiliated to Dalian University from 2012 to 2017 were collected,risk management was not implemented in outpatient and emergency departments from 2012 to 2014,and risk management was implemented from 2015 to 2017,a retrospective comparative analysis was made on the incidence of medical disputes and complaints in each year in 2012-2017.Results From 2012 to 2014,138,121 and 116 medical disputes and complaints occurred,accounting for 0.016%,0.013%and 0.011%respectively;from 2015 to 2017,67,52 and 37 medical disputes and complaints occurred,accounting for 0.006%,0.004%and 0.002%respectively.The total incidence of medical disputes and complaints in 2015-2017 was significantly lower than that in 2012-2014 (P＜0.05).Conclusion Risk management plays a significant role in preventing outpatient and emergency medical disputes and complaints,and has a forward-looking positive significance in promoting medical risk management and control,which is worth learning. 2018 Vol. 25 (27): 140-142 [Abstract] ( 122 ) HTML (36 KB)  PDF  (0 KB)  ( 26 ) 143 Effect of nursing quality management in orthopedics department of traditional Chinese medicine in continuous quality improvement CHENG Xiao-hong;QIAN Cui-yu Objective To explore the effect of nursing quality management in orthopedics department of traditional Chinese medicine in continuous quality improvement.Methods A total of 120 patients with orthopaedic diseases admitted to our hospital from January,18th2016 to April,26th2018 were selected as the research objects,and the patients were divided into the two groups randomly using computer randomized grouping method and each group had 60 cases.The observation group was administered with continuous quality improvement,while the control group was administered with routine management.The nursing satisfaction,scores of mental status,quality of life between the two groups were compared.Results The total nursing satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The self-rating depression scale(SDS)and self-rating anxiety scale(SAS)scores of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05).The physical field,psychological field,social field and material life of the observation group were higher than those of the control group,the differences were statistically significant(P＜0.05).Conclusion Nursing quality management in orthopedics department of traditional Chinese medicine is of great value for continuous quality improvement,and it can significantly improve the depression and anxiety of patients,improve the nursing satisfaction and quality of life of patients,and is worthy of clinical promotioin and application. 2018 Vol. 25 (27): 143-145 [Abstract] ( 121 ) HTML (34 KB)  PDF  (0 KB)  ( 15 ) 146 Analysis of Human Genetic Resource Administration of China in international cooperative clinical trial HOU Chun-hua;TIAN Li-juan In order to strengthen the management of human genetic resources in China and better adapt to the development of clinical trials in China,this paper analyzes the development process,implementation effect and challenges of human genetic resources management in international cooperative clinical trials in China.It is concluded that in the international cooperative clinical trials in China,the management of human genetic resources is gradually standardized,the rational utilization and protection of human genetic resources are gradually strengthened,and the standardization of clinical trials is gradually improved.However,there are still some problems,such as imperfect relevant laws and regulations,unclear regulatory responsibilities,and lack of initiative in applicants'declaration.Therefore,the relevant departments still need to further improve the relevant laws and regulations,clarify supervision responsibilities,increase publicity and guidance,and encourage applicants to declare actively. 2018 Vol. 25 (27): 146-148 [Abstract] ( 111 ) HTML (36 KB)  PDF  (0 KB)  ( 27 ) 149 Analysis of disinfection and biological vector control in Dandong City in 2017 ZOU Chao;CHEN Jun;CUI Rong-min Objective To get known the status quo of disinfection and biological vector control in Dandong City in order to strengthen the surveillance and control of infection in medical institutions and vector infectious diseases.Methods In 2017,the surveillance on the disinfection effect and vectors in medical institutions in Dandong City was conducted,and the monitoring results were analyzed and studied.Results A total of 1153 samples were collected from monitoring medical institutions in Dandong City in 2017,and 1140 were qualified,and the rate of qualification was 98.87%.Biological vector surveillance showed that the density of mosquitoes,flies,cockroach,and mice were 1.68 pieces/(set·h),0.63 piece/(cage·h),0.06 piece/sheet,and 1.40%in turn.Conclusion In 2017,the quality of disinfection in medical institutions in Dandong City is generally good with a satisfactory control of vector density. 2018 Vol. 25 (27): 149-151 [Abstract] ( 91 ) HTML (35 KB)  PDF  (0 KB)  ( 24 ) 152 Efficacy evaluation of microlecture+flipped classroom in the teaching of pathological section in higher vocational nursing JIN Wen;WANG Bo;YANG Mei;ZHU Zhi-wen;LUO Xue-lian;ZHA Cheng Objective To study the application effect of microlecture+flipped classroom in the teaching of pathology histology in higher vocational nursing under the background of Internet.Methods A total of 252 students from four classes of nursing specialty in grade 2016 of our college were selected to be included in the study.133 students from two classes were randomly selected as the experimental group and 119 students from two classes as the control group.The experimental group was given microlecture+flipped classroom teaching method,while the control group was given traditional teaching method.Questionnaires were used to investigate the satisfaction of students with the current implementation of teaching mode in the two groups,and the score of experimental reports were compared between the two groups.Results The total satisfaction degree of students on teaching content design,learning style,learning effect,improvement of learning ability and team consciousness cultivation in the experimental group were higher than those of the control group (P＜0.05).The evaluation achievement of the experimental report in the experimental group were significantly higher than that of the control group (P＜0.05).Conclusion The implementation of microlecture and flippedover classroom under the background of Internet is helpful to improve the teaching and learning effect of nursing pathology histology in higher vocational nursing,and is worthy of further study and application 2018 Vol. 25 (27): 152-154转158 [Abstract] ( 116 ) HTML (39 KB)  PDF  (0 KB)  ( 25 ) 155 Investigation of teaching methods based on disease mechanism to enlight‐en medical students′clinical thinking LIU Xiang;YANG Hui At present,the teaching methods of training medical students'clinical thinking includes case discussion,teaching rounds,PBL,etc.Each has its advantages and disadvantages.For example,case discussion is closely related to clinical application,but students are often not deep enough to discuss.Teaching rounds pay attention to clinical skills such as medical history collection and physical examination,but the training of clinical thinking is relatively small.This study attempts to enlighten medical students'clinical thinking on the basis of in-depth explanation of the pathophysiological mechanism of diseases,to help students establish clinical thinking from phenomena to essence,and to explore the implementation of this teaching method and the aspects that can be improved. 2018 Vol. 25 (27): 155-158 [Abstract] ( 108 ) HTML (37 KB)  PDF  (0 KB)  ( 24 ) 159 A qualitative study of nursing undergraduates on diversified teaching model YAO Ju-qin;PAN Si;WU Wei-zi;CHEN Jia;LI Xian-hong Objective To deeply understand the experience of nursing undergraduates on diversified teaching model in China.MethodsFrom October 2017 to January 2018,30 nursing undergraduates reading at Central South University were interviewed with 4 groups.All the interview recordings were transcribed into Word documents and coded and classified by thematic analysis method.Results Nursing undergraduates have carried out a variety of teaching methods,and reflected in the pre-class preview,classroom display and after-class homework three links.Diversified teaching mode enlivens classroom atmosphere,strengthens students'mastery of knowledge,improves students'comprehensive ability,and reduces students'anxiety about exams to a certain extent.However,there are some drawbacks in the current implementation process,such as providing a chance for some students to"paddle"and improper use of diversified teaching methods may reduce the quality of teaching,or become a"sweet burden"for students.Students suggest that the development of diversified teaching model should be light of form and emphasis on connotation;diversified courses should be selected according to the nature and difficulty of the curriculum,and the number of courses carried out each semester;teachers'overall quality and training of diversified classroom control ability should be strengthened.Conclusion While affirming the effective value of diversified teaching mode in nurses training,we should objectively evaluate its shortcomings and take effective measures to improve it so as to maximize the advantages and functions of diversified teaching mode and train nurses with all-round development. 2018 Vol. 25 (27): 159-164 [Abstract] ( 107 ) HTML (66 KB)  PDF  (0 KB)  ( 15 ) 165 Exploration of bilingual teaching mode in medical eight year probationary course DING Bo-ni;ZHAO Yu-jun;TIAN Sha Eight-year clinical medicine education is a brand-new training mode,aiming at training more high-level medical personnel.English level is one of the key points in the eight-year internship course,so it is a difficult task to explore the bilingual teaching mode of the eight-year internship course under the new situation.In order to improve the effect of bilingual teaching in medical eight-year probation course,this paper puts forward some relevant bilingual teaching methods,including training key bilingual teachers,arousing students'enthusiasm for learning,choosing appropriate bilingual teaching materials and flexibly applying various teaching methods according to students'actual conditions(such as question-based learning,typical case study,bilingual Seminar teaching method in Chinese and English,training bilingual standardized patients,making full use of multimedia teaching,organizing bilingual teaching rounds,writing English medical records,making full use of foreign students'resources,conducting probation examinations from time to time and summarizing and collecting them after class to collect feedback from students).It is hoped that through the application of the above-mentioned teaching methods,a bilingual teaching model suitable for eight-year medical probation course will be established to train high-quality compound medical talents to meet the future medical needs. 2018 Vol. 25 (27): 165-167转173 [Abstract] ( 116 ) HTML (38 KB)  PDF  (0 KB)  ( 18 ) 168 Effects of diversified nursing and caring services on post-abortion psychological and physical conditions in unexpected pregnancies YANG Wen-li;HUANG Qun;LIU Zhao-xia Objective To explore the role of diversified nursing and care service mode in improving the physiological and psychological status of women with unplanned pregnancy after abortion.Methods From August 2017 to February 2018,80 pregnant women who underwent artificial abortion in Yingtan Maternal and Child Health Care Hospital were selected and double-blind method was randomly divided into control group and observation group,40 cases in each group.In the control group,routine nursing intervention was used after abortion,and the observation group was treated with multiple nursing and caring service model on the basis of the control group.The psychological and physiological status of the two groups were compared.Results The scores of anxiety and depression symptoms in the two groups were lower than those before the intervention,the scores of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05）,the vaginal bleeding time of the observation group was shorter than that of the control group,and the postoperative complications in the observation group was lesser than that in the control group.The contraceptive knowledge understanding rate and total satisfaction evaluation of nursing services were higher than those of the control group,and the rate of unwanted pregnancy was lower than that of the control group,and the differences between the two groups were statistically significant(P＜0.05）.Conclusion The intervention of multiple nursing and caring service can effectively improve the psychological and physiological status of female abortion patients with accidental pregnancy. 2018 Vol. 25 (27): 168-170 [Abstract] ( 112 ) HTML (36 KB)  PDF  (0 KB)  ( 26 ) 171 Correlation analysis between loneliness and social support in elderly inpatients with psychosis ZHENG Chan-yan;LUO Wei-ling Objective To study the correlation between loneliness and social support in elderly inpatients with psychosis.Methods A total of 107 elderly inpatients with psychosis admitted to our hospital from March 2015 to March 2017 were selected as the study group.At the same time,107 non-psychiatric inpatients in our hospital were selected as the control group.The general data of all participants were collected and summed up,and the correlation between loneliness and social support in elderly inpatients with psychosis was evaluated by social support rating scale and loneliness scale.Results After observing the scores of the two groups,it was found that objective support,subjective scoring,use of support,and total score in the social support of the study group were lower than those in the control group.The loneliness score of the study group was higher than that of the control group (P＜0.05）.The loneliness score of the study group was negatively correlated with objective support,subjective scoring,use of support,and total score respectively,which was displayed statistical significance(P＜0.05）.Conclusion The loneliness of hospitalized elderly patients with psychiatric disorders is relatively strong,and there is a certain correlation with the lack of social support.If effective intervention can be taken in time,family and social support will be strengthened to ease patient's bad emotion so as to promote the rapid recovery of the disease. 2018 Vol. 25 (27): 171-173 [Abstract] ( 109 ) HTML (31 KB)  PDF  (0 KB)  ( 20 ) 174 Effectiveness of application of comprehensive nursing intervention in the treatment of acute myocardial infarction patients TAN Li Objective To explore the effectiveness of application of comprehensive nursing intervention in patients with acute myocardial infarction(AMI).Methods A total of 64 patients with AMI treated in our hospital from January to December 2017 were selected as the objects of this research and randomly divided into the observation group and the control group,32 cases in each group.The observation group was received comprehensive nursing intervention;while,the control group was received routine nursing intervention.The self-efficacy,social support,coping style score and prognosis of the two groups before and after intervention were observed and compared.Results There was no statistically significant difference between the two groups of patients in pre-interventional self-efficacy,social support,confrontation,avoidance and resignation coping,and the score of mental resilience(P＞0.05）.The post-interventional selfefficacy,social support and confrontation coping of observation group and control group had statistically significant difference in contrast with pre-interventional ones(P＜0.05）;and the post-interventional avoidance coping and resignation coping of the observation group were significantly lower than those before the intervention，with statistically significant difference(P＜0.05）.The post-interventional scores of mental resilience of observation group and the control group were significantly better than those before intervention,with statistically significant difference (P＜0.05）.The post-interventional self-efficacy,social support,confrontation coping and mental resilience score of observation group were higher than those of control group,with statistically significant difference (P＜0.05）;and the post-interventional avoidance coping and resignation coping scores of observation group were lower than those of control group,with statistically significant difference (P＜0.05）.The mortality of the observation group was significantly lower than that of the control group,with statistically significant difference (P＜0.05）.Conclusion Comprehensive nursing intervention significantly improves the self-efficacy,social support,coping style and the prognosis of the patients with myocardial infarction,which is worthy of clinical application. 2018 Vol. 25 (27): 174-176 [Abstract] ( 108 ) HTML (34 KB)  PDF  (0 KB)  ( 24 ) 177 Application effect of rehabilitation nursing in traumatic fracture patients LI Ting;LIU Ai-mei;ZHONG Xiao-di;TANG Wen-lin;CHEN Xi Objective To analyze the application effect of rehabilitation nursing in traumatic fracture patients.Methods Eighty patients with traumatic fractures who received treatment in our hospital from March 2015 to April 2017 were selected as study subjects.According to the sequence of patients admitted to the hospital,they were divided into observation group and control group,40 cases in each group.The control group was provided routine care respectively,the observation group was provided with rehabilitation nursing.The differences in postoperative fracture pain,swelling,and rehabilitation indicators were compared between the two groups.Results After the nursing,abdominal distention value and the pain scores of the two groups were lower than those before nursing (P＜0.05）.The abdominal distention value and pain degree of the observation group after nursing was lower than that of the control group(P＜0.05）.The scores of the joint function and nursing satisfaction of the observation group after nursing were higher than those of the control group.The hospital stay and postoperative healing time were shorter than those in the control group,the differences were statistically significant(P＜0.05）.Conclusion Rehabilitation nursing in patients with traumatic fractures can effectively alleviate the degree of pain in patients and speed up the recovery process,which is worthy of clinical promotion. 2018 Vol. 25 (27): 177-179 [Abstract] ( 100 ) HTML (35 KB)  PDF  (0 KB)  ( 23 ) 180 The family support system evaluates the effect of breastfeeding CHEN Xiao-yan Objective To study the effect of family support system on improving breastfeeding.Methods A total of 166 parturient patients admitted to our hospital from February 2017 to February 2018 were selected as the study subjects,and were divided into the control group and the experimental group according to the treatment time,83 cases in each group.The control group did not intervene,and the experimental group was given the family support system.The first active breast-feeding time,the number of active breastfeeding per day,the exclusive breastfeeding rate during the neonatal period,and the knowledge of the nursing health knowledge was campared between two groups.Results The first active lactation time in the experimental group was earlier than that in the control group,active feeding times every day in the experimental group was more than that in the control group,birth rate of exclusive breastfeeding during hospitalization and awareness of nursing health knowledge in the experimental group were higher than that in the control group,the differences were statistically significant(P＜0.05）.Conclusion The implementation of a home support system for mothers and babies can allow mothers to acquire more knowledge about breastfeeding,increase the success rate of breastfeeding,and increase their ability to care for newborn babies. 2018 Vol. 25 (27): 180-182 [Abstract] ( 103 ) HTML (35 KB)  PDF  (0 KB)  ( 26 ) 183 Comparison of different cleaning and disinfection methods applied to endoscopic instruments SHU Yu-lan Objective To analyze the effect of different cleaning and disinfection methods applied to endoscopic instruments.MethodsThe gastric endoscopy which should be cleaned and sanitizing from January to December 2016,was selected as the research object.According to the cleaning and disinfection methods of endoscopic instruments,the endoscopy was divided into two groups,which were cleaned by manual cleaning and integrated cleaning workstation respectively.The former was used as a manual group,and the latter was used as a cleaning workstation group.After the cleaning,80 endoscopes were randomly selected from the manual group and cleaning workstations group.The results were compared between the two groups of endoscopy bacteria culture results and the normalization,and the manual cleaning group and the cleaning workstation group were compared with the manual time,the total time and the time of disinfection.Results①The workstation group,79 were qualified,1 were unqualified and the qualified rate was 98.8%;the manual cleaning group,58 were qualified,22 unqualified,and the qualified rate was 72.5%.The qualified rate of cleaning workstation group was higher than that of manual cleaning group,and the difference was statistically significant(P＜0.05）.The results showed that the cleaning workstation group was standardized,the results showed that the cleaning workstation group was 75 were standard,5 were non standard,and the standard rate was 93.8%;the manual group,70 were standard,10 were non standard,and the standard rate was 87.5%.The standard rate of the cleaning workstation group was significantly higher than that of the manual group,the difference was statistically significant(P＜0.05）.②the average time of endoscopy in the cleaning workstation group of(3.9±0.5)h was shorter than that of the manual group(6.8±0.6)h,and the disinfection time of(24.5±2.5)min in the cleaning workstation group was significantly shorter than that of the manual group(30.2±2.3)min,and there were significant difference in groups(P＜0.05）,and the difference between the two groups of total time consuming was not statistically significant(P＞0.05）.Conclusion The integrated cleaning workstation can significantly improve the cleaning effect and efficiency of gastric endoscopy,and is worthy of clinical application. 2018 Vol. 25 (27): 183-185 [Abstract] ( 112 ) HTML (32 KB)  PDF  (0 KB)  ( 22 ) 186 Effect of detailed nursing intervention in operation room on controlling postoperative infection after endoscopic nephrectomy for patients with renal tumors CHEN Man-gui Objective To explore the effect of detailed nursing intervention in operation room on controlling postoperative infection after endoscopic nephrectomy.Methods A total of 74 patients with renal tumors undergoing endoscopic nephrectomy from June 2015 to August 2016 were selected as the research subjects.According to random number table method,they were divided into the control group and the observation group,47 cases in each group.The patients in the control group were treated with routine nursing,and the patients in the observation group were treated with detail nursing intervention in on the basis of the control group.The postoperative recovery was observed and analyzed in the two groups (the time of ambulation，drainage tube indwelling,hospitalization and feeding,anus exhaust time after operation)and postoperative complications (urinary leakage,urinary cyst and lower renal function loss,etc.),and the incidence of infection.Results The patients in the observation group were shorter than the control group(P＜0.05）,and the incidence of postoperative complications (5.40%)in the observation group was lower than that of the control group(21.62%),and the postoperative infection rate (8.11%)in the observation group was lower than that of the control group(27.03%),the differences were statistically significant(P＜0.05）.Conclusion The detailed nursing intervention in the operation room can effectively reduce the incidence of postoperative infection,reduce the incidence of complications and promote the recovery of patients with nephrectomy with endoscopic nephrectomy. 2018 Vol. 25 (27): 186-188 [Abstract] ( 116 ) HTML (33 KB)  PDF  (0 KB)  ( 25 ) 189 Impact of psychological counseling and health guidance on incision pain and living ability in patients after hemorrhoid surgeries ZHENG Li-ying;DENG Shu-hong Objective To investigate the influence of psychological counseling and health guidance on incision pain and living ability in patients after hemorrhoid surgeries.Methods A total of 100 patients performed with hemorrhoid surgeries in our hospital from January 2016 to March 2018 were selected as the study subjects.According to the random number table method,they were equally divided into control group and observation group,50 cases in each group.Patients in the control group were treated with routine care,while in the observation group,participants were provided with psychological counseling and health guidance on the basis of the control group.Visual analogue scale(VAS)scores of incision pain 1,3,5 day after treatment and self-care ability were compared between the two groups.Results The VAS score on the 3rd day after treatment in both groups were lower than that on the 1st day after treatment.The VAS score on the 5th day after treatment was lower than that on the 3rd day after treatment with statistical significance(P＜0.05）.In the observation group,the VAS scores 1,3,5 day after treatment were lower compared with those at the corresponding period in the control group with statistical significance(P＜0.05）.The excellent and good rate of living ability in the observation group was 96.00%,significantly higher than that in the control group accounting for 82.00%with significant difference (P＜0.05）.Conclusion For patients after hemorrhoid surgeries,application of psychological counseling and health guidance can alleviate postoperative incision pain,improve the patient's self-care ability,and ameliorate their quality of life. 2018 Vol. 25 (27): 189-191 [Abstract] ( 95 ) HTML (34 KB)  PDF  (0 KB)  ( 4 ) 192 Clinical nursing effect of position management after hip joint replacement on the prevention of prosthesis dislocation HUANG Mei-hua;HUANG Mei-xiang Objective To observe the clinical nursing effect of position management after hip joint replacement on the prevention of prosthesis dislocation.Methods A total of 34 patients with artificial hip arthroplasty in our hospital from August 2016 to December 2017 were enrolled as study subjects.By odd or even number,they were divided into control group (n=17)and study group (n=17).In the control group,routine nursing was applied,while in the study group,on the basis of the control group,position management was adopted.The compliance rate,the incidence of prosthesis dislocation,score knowledge of preventing prosthesis dislocation and the improvement of hip function were compared and evaluated.Results The compliance rate of the study group was higher than that of the control group.The incidence of prosthesis dislocation was lower than that of the control group with statistical significance(P＜0.05）.In the study group,score knowledge of prosthesis dislocation prevention and the hip function scores were higher compared with those in the control group with statistical significance (P＜0.05）.Conclusion Postural management after hip arthroplasty is beneficial to prevent prosthesis dislocation,increase compliance rate and improves hip function,which is worthy of clinical reference and further promotion. 2018 Vol. 25 (27): 192-194 [Abstract] ( 87 ) HTML (34 KB)  PDF  (0 KB)  ( 16 ) 195 Effect of perioperative nursing care on patients undergoing scar surgery after burn KANG Hua;TAO Jian Objective To explore the effect of perioperative nursing care in patients undergoing scar surgery after burn.MethodsFrom January to December 2017,96 patients with post-burn scar plastic surgery were selected as the objects of study.They were randomly divided into experimental group and control group,48 patients in each group.The patients in the control group were given routine operation nursing,and the patients in the experimental group were received targeted perioperative nursing on this basis.The postoperative landing time,hospitalization time,nursing satisfaction rate and complications were compared between the two groups.Results The postoperative landing time and hospitalization time in the experimental group were shorter than those in the control group,and the total incidence of complications in the experimental group was significantly lower than that in the control group (P＜0.05）.The total satisfaction rate of nursing quality in the experimental group was 93.7%,which was significantly higher than that in the control group 81.2%,the difference was statistically significant(P＜0.05）.Conclusion The perioperative nursing care of the patients with scar plastic surgery after burn can promote the recovery of the patients,reduce the incidence of complications during the perioperative period,ensure the effect of surgical treatment,and improve the nursing satisfaction of the patients. 2018 Vol. 25 (27): 195-197 [Abstract] ( 114 ) HTML (36 KB)  PDF  (0 KB)  ( 30 ) 198 Application effect of whole course nursing in patients undergoing abdominal operation CHENG Ping Objective To explore the clinical effect of whole course nursing intervention on patients undergoing abdominal surgery.Methods From December 2015 to October 2017,90 patients with abdominal surgery were selected and divided into control group and observation group by drawing lots,45 cases in each group.In the control group,routine nursing mode was used in the operating room,while in the observation group,the whole nursing mode was adopted on the basis of the control group.The scores of mental state,blood pressure,heart rate and total nursing satisfaction were compared between the two groups.Results The psychological state score of the observation group was lower than that of the control group.The level of blood pressure and heart rate in the observation group was significantly lower than that in the control group (P＜0.05）,and the total satisfaction degree of nursing in the observation group was 97.78%,which was higher than that in the control group (71.11%),the difference was statistically significant(P＜0.05）.Conclusion The nursing staff choose the whole nursing mode to nurse the patients with abdominal operation,and obtain the ideal effect in the aspects of improving the psychological state,reducing the stress reaction and improving the degree of satisfaction of nursing,so as to promote the recovery of the patients with abdominal surgery. 2018 Vol. 25 (27): 198-200 [Abstract] ( 103 ) HTML (33 KB)  PDF  (0 KB)  ( 18 ) 201 Application effect of humanized nursing management in the nursing of patients with essential hypertension XIAO Ling;XIE Ai-xiu;WU Shun-xiu Objective To explore the application effect of humanized nursing management in the nursing of patients with essential hypertension.Methods A total of 60 patients with essential hypertension who were admitted to our hospital from June 2016 to May 2018 were selected as research subjects.According to the randomization method of patient admission number,it was divided into nursing intervention group and reference group,30 cases in each group.The nursing intervention group was given humanized nursing management.The reference group was given routine nursing care management.The nursing effects of the two groups of patients were compared.Results The quality of life score in the nursing intervention group was higher than that in the reference group,and the difference was statistically significant(P＜0.05）.The scores of self-management ability of the patients in the nursing intervention group were higher than those in the reference group,and the differences were statistically significant(P＜0.05）.The medication adherence in the nursing intervention group was 96.7%,which was higher than that in the reference group (76.7%),and the difference was statistically significant(P＜0.05）.Conclusion Humanized nursing management interventions in the treatment of patients with essential hypertension can improve their self-management awareness and ability.At the same time,it can effectively improve the quality of life of patients.Therefore,the humanized nursing management model has a high application value in patients with essential hypertension. 2018 Vol. 25 (27): 201-203 [Abstract] ( 96 ) HTML (35 KB)  PDF  (0 KB)  ( 17 ) 204 Application of self-made transparent compression bag in nursing after permanent pacemaker implantation WANG Yan-ping;LI Li-jun;LI Hui Objective To investigate the effect of self-made transparent compression bag after permanent pacemaker implantation.Methods A total of 120 patients undergoing permanent pacemaker implantation from November 2012 to June 2017 in our hospital were divided into observation group and control group according to the lottery method,60 cases in each group.Patients in the observation group were provided with self-made transparent compression bag for postoperative oppression,while in the control group,self-made sandbag or salt bag after the operation was applied.The incision bleeding,capsular hematoma,and electrode dislocation occurred after the operation,comfort degree such as pain,dysuria,and sleep disorder,and compression bag shift and slippage were compared in the two groups.Results There was no significant difference in the incidence of incision bleeding,capsular hematoma,and electrode dislocation between the two groups (P＞0.05）.The incidence of postoperative pain,dysuria,sleep disorder,compression bag shift and slippage was lower in the observation group than that in the control group,with a significant difference (P＜0.05）.Conclusion The application of self-made transparent compression bag after permanent pacemaker implantation can not only ensure the safety of the patient,but also increase the comfort of the patient.It can reduce the workload of nursing staff,increase patient's satisfaction,and nursing quality by medical personnel,which is worthy of promotion in clinic.However,in the process of using,avoid contact with sharp things is necessary in order to prevent the transparent compression bag ruptured. 2018 Vol. 25 (27): 204-206 [Abstract] ( 120 ) HTML (35 KB)  PDF  (0 KB)  ( 23 ) 207 Application effect of targeted nursing in 45 children with pneumonia FANG Hai-yan Objective To investigate the application effect of targeted nursing in children with pneumonia.Methods A total of 45 children with pneumonia admitted to our hospital from December 2014 to October 2015 were selected.They were divided into control group(n=22)and observation group(n=23)by a random comprehensive sequential method.In the control group,routine care for pneumonia was used,while in the observation group,targeted nursing was adopted.The nursing effect was compared in the two groups.Results The duration of fever bringing down in the observation group was(2.1±0.3)d and hospital stay was(4.5±1.0)d,significantly shorter than that in the control group([4.9±0.4]d and[8.7±2.3]d respectively),which was displayed statistical significance(P＜0.05）.The totla effectiveness rate in the observation group was 95.65%,significantly higher than that in the control group accounting for 72.73%,with a significant difference(P＜0.05）.The total satisfaction of nursing from patients and families in the observation group was 100%,significantly higher than that of the control group accounting for 77.27%with a statistical difference(P＜0.05）.Conclusion For pediatric pneumonia,application of targeted nursing has the advantages of rapid fever reduction,obvious symptom relief,and remarkable effect,which is beneficial to increasing nursing satisfaction.It is worthy of further exploration and promotion in clinical practice. 2018 Vol. 25 (27): 207-209 [Abstract] ( 101 ) HTML (34 KB)  PDF  (0 KB)  ( 22 ) 210 Analysis of the responsibility system group in the early postoperative enteral nutrition nursing of gastric cancer LIU Zhen;XU Yue-yuan;XU Yue-hong;YANG Ai-qing Objective To explore the practical effect of the application of the analytical responsibility group in the early enteral nutrition（EN)nursing after the operation of gastric cancer.Methods From May 2013 to 2 June 2017,underwent surgical treatment in People's Hospital of Yingtan City for patients with gastric cancer were selected 68 cases as the research object.They the observation group were randomly divided into the observation group (35 cases)and the control group(33 cases).The control group was received routine nursing care,the observation group was took responsibility group nursing.The nutritional status,postoperative recovery,postoperative complications and nursing service evaluation were compared and analyzed between the two groups.Results The nutritional status of the observation group was better than that of the reference group (P＜0.05）.The bowel sound recovery,exhaust,defecation,food intake and hospital stay in the observation group were shorter than those in the reference group(P＜0.05）.The incidence of postoperative complications in the observation group was lower than that in the reference group,but the difference was not statistically significant(P＞0.05）.The satisfaction of the nursing service in the observation group was higher than that in the reference group,the difference was statistically significant(P＜0.05）.Conclusion The use of responsibility group in postoperative gastric cancer patients can provide better effect of enteral nutrition nursing,which is more conducive to postoperative recovery of patients,and nursing services can also get higher evaluation. 2018 Vol. 25 (27): 210-212 [Abstract] ( 104 ) HTML (35 KB)  PDF  (0 KB)  ( 30 ) 213 Effect of pre-hospital emergency nursing route in pre-hospital emergency treatment for stroke patients HUANG Hui-zhi Objective To explore the application effect of pre-hospital emergency nursing route on stroke patients.Methods A total of 150 stroke patients from May 2016 to May 2017 admitted into our emergency rescue center were selected as study subjects.They were divided into two groups by envelope randomization,75 cases in each group.In conventional group,the traditional nursing model was used,while in the experimental group,pre-hospital emergency nursing route as an intervention was adopted.The emergency time,mortality,and disability rate between the two groups were compared.Results In the experimental group,time to call for help to pre-hospital emergency rescue and time to call for help to treatment in hospital were (17.78±8.36)min and (31.98±10.25)min,which were significantly shorter than those of the conventional group([26.35±7.56]min and[43.25±11.68])min respectively,which were displayed statistical significance (P＜0.05）.The mortality and disability rate in the experimental group were 5.33%and 40.00%,which were much lower than those in the conventional group,accounting for 16.00%and 68.00%respectively with statistical significance(P＜0.05).Conclusion For stroke patients,pre-hospital emergency care route is beneficial to shortening rescue time and reducing the disability and mortality. 2018 Vol. 25 (27): 213-215 [Abstract] ( 104 ) HTML (33 KB)  PDF  (0 KB)  ( 21 ) 216 Effect of systematic nursing intervention on post-operative pain，emotion and quality of life in patients undergoing endoscopic sinus surgery SUN Yan Objective To explore the effects of systematic nursing intervention on pain,emotion and quality of life in patients undergoing endoscopic sinus surgery.Methods Altogether 85 patients who underwent endoscopic surgery in our hospital from April 2015 to April 2016 were selected as the control group;while,another 85 patients who received endoscopic sinus surgery in our hospital from May 2016 to May 2017 were selected as observation group.The control group was adopted routine nursing,and the observation group was took systematic nursing intervention.The pre-and post-operative pain,negative emotion and post-operative quality of life score were compared between two groups.Results The pre-operativevisual analogue scale(VAS)score(6.35±1.29),self-rating depression scale(SDS） score(55.47±5.58)and self-rating anxiety scale(SAS） score(54.27±6.38)of observation group had no statistically significant difference in comparison with those of control group([6.27±1.24],[55.39±5.61]and[53.76±6.51]score),(P＞0.05）.The postoperative VAS,SDS and SAS scores of the observation group were(3.33±0.35),(49.27±3.01)and(46.72±4.16)score,lower than those of the control group([4.27±0.84],[52.16±3.42]and[50.27±5.24]score),with statistically significant difference (P＜0.05）.The score of each dimension of post-operative scale quality of life comprehensive assessment questionnaire(GQOL I274)of the observation group were higher than those of the control group,with statistically significant difference(P＜0.05）.Conclusion Application of systematic nursing intervention in patients undergoing endoscopic sinus surgery can improve their negative emotions such as anxiety and depression,relieve postoperative pain and ameliorate their quality of life. 2018 Vol. 25 (27): 216-218 [Abstract] ( 96 ) HTML (35 KB)  PDF  (0 KB)  ( 24 ) 219 Effect of rehabilitation nursing in nursing care of patients with enterostomy LIU Yong-lian;LIU Yan-ping;FANG Qin;HUANG Li-jun;XING Le Objective To explore the effect of rehabilitation nursing and quality of life (QOL)on patients with enterostomy,and to provide guidance for clinical practice.Methods From January 2015 to February 2018,72 patients with enterostomy in our department were randomly divided into experimental group(n=40)and control group(n=32).Rehabilitation nursing was applied in experimental group and routine nursing was used in control group.The quality of life score,psychological status score,satisfaction score,incidence of complications and length of stay were compared between two group.Results The quality of life score of the patients in the experimental group was higher than that of the control group,and the psychological status score was lower than the control group,and the differences were statistically significant(P＜0.05）.The total incidence of complications in the experimental group was 2.50%lower than that of the control group (25%),the difference was statistically significant(P＜0.05）;the satisfaction score of the experimental group was(8.25+0.31)points,which was higher than that of the control group,and the length of stay ([28.12+2.31]d)was shorter than that of the control group(P＜0.05）.Conclusion It is feasible to carry out rehabilitation nursing for patients with enterostomy,which is helpful to improve the quality of life of patients. 2018 Vol. 25 (27): 219-221 [Abstract] ( 99 ) HTML (34 KB)  PDF  (0 KB)  ( 22 )

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