急性期精神分裂症患者WCST执行功能与PANSS五因子分的相关性研究

Abstract
Figure/Table
References (17)
Related Citation (4)

Download: PDF (0 KB) HTML (45 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the correlation between Wisconsin card classification test(WCST)executive function and five factor score of PANSS in patients with schizophrenia at acute stage.Methods Patients with schizophrenia at acute stage hospitalized in our hospital from May to November 2017 were selected and 200 patients were included in the plan.The relevant demographic data and disease data in patients included were counted,such as age,age of onset,course of disease,length of education,etc.WCST was used to assess the executive function of the patients at the end of the first week of treatment.Total test times,correct response number,persistent error number,random error number and completing classification number were counted.At the end of the first week of treatment,positive and negative symptom scale(PANSS)was used to assess the psychiatric symptoms of patients in acute stage.Principal component analysis was performed on 30 items of PANSS,among them,9 items forming negative factors,7 items forming cognitive factors,4 items forming positive factors,4 items forming excitatory factors and 6 items forming anxiety and depression factors.The score of various factor was calculated respectively.Results WCST executive function scores of patients with different educational years,different age of onset and different negative and positive scores of PANSS were statistically significant(P＜0.05).The educational years of the patients was negatively correlated with the total tests number,persistent error number and random error number(r=-0.01,-0.23,-0.18)respectively,and the educational years of the patients was positively correlated with correct response number,completing classification number(r=0.35,0.37)respectively.The age of onset was negatively correlated with persistent error number and random error number(r=-0.14,-0.35)respectively,and the age of onset was positively correlated with total test times,correct response number,completing classification number(r=0.31,0.17,0.14)respectively.The positive score of PANSS was negatively correlated with total test times,persistent error number and random error number (r=-0.09,-0.05,-0.08)respectively,and the positive score of PANSS was positively correlated with correct response number,completing classification number(r=0.17,0.15)respectively.The negative scoer of PANSS was negatively correlated with correct response number,completing classification number(r=-0.13,-0.36)respectively,and the negative score of PANSS was positively correlated with total test times,persistent error number and random error number(r=0.35,0.26,0.25)respectively.Pearson correlation analysis showed that the correct response number and completing classification number of WCST executive function were negatively correlated with negative symptom score of PANSS,and the persistent error number and random error number were positively correlated with negative symptom score,while the other items were not significantly correlated.Conclusion WCST executive function defect exists in patients with schizophrenia at acute stage,and it has certain correlation with negative symptoms.The study of executive function in patients with schizophrenia at acute stage will be more conducive to diagnosis,disease prediction,prognosis judgment,treatment and rehabilitation of patients.

Key words： Patients with schizophrenic WCST executive function Five factor score of PANSS Correlation study

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	XIAO Jian-wen
	HUANG Li
	SHEN Ying

Cite this article:

XIAO Jian-wen,HUANG Li,SHEN Ying. Correlation study between WCST executive function and five factor score of PANSS in patients with schizophrenia at acute stage[J]. 中国当代医药, 2018, 25(27): 11-15.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I27/11

[1]	Gallhofer G，Haefs W，Konig V，et al.1-Onkologische Erkrankungen[J].Klinikleitfaden Medizinische Rehabilitation，2011，151（2）：1-129.
[2]	张怀晨，苏中华，张明，等.急性期精神分裂症住院患者激越症状与院前冲动攻击行为相关性分析[J].精神医学，2016，29（3）：177-181.
[3]	王金成，赵晓川，王学义.精神分裂症执行功能的研究进展[J].中国健康心理学，2015，22（9）：1434-1437.
[4]	姜佐宁.国际疾病分类第十版（ICD-10）中关于使用精神活性物质引致心理与行为障碍的分类与诊断指导 [J].中国药物依赖性通报，1989，11（3）：4-7.
[5]	薛昀赟.精神分裂症和精神病性抑郁症患者感觉运动门控的研究[J].中国健康心理学，2016，13（8）：43-47.
[6]	卓恺明，杨治良，宋振华.急性期精神分裂症的基于事件前瞻记忆研究[J].上海交通大学学报（医学版），2016，31（12）：1724-1728.
[7]	刘明.精神分裂症认知功能损害的特点及干预研究[D].太原：山西医科大学，2017.
[8]	吴大兴，谭长连，颜莉蓉，等.精神分裂症执行功能障碍患者工作记忆 fMRI研究[J].中国医科大学学报，2017，17（6）：737-740.
[9]	刘登堂，杨治良，王彦，等.急性期精神分裂症返回抑制的时间进程[J].心理科学，2015，26（5）：1049-1053.
[10]	李玥，邹义壮，李建明.精神分裂症认知功能神经心理学评定的研究进展[J].中国健康心理学，2017，21（12）：1118-1121.
[11]	王湘，颜莉蓉，谭长连，等.缺陷型及非缺陷型精神分裂症执行功能障碍的fMRI初步研究[J].中国医学影像技术，2017，23（8）：1130-1133.
[12]	司天梅，杨建中，舒良，等.阳性和阴性症状量表（PANSS，中文版）的信、效度研究[J].中国心理卫生，2015，16（1）：45-47.
[13]	孙兆明，孙学礼，王欣，等.精神分裂症认知障碍及其与阴性阳性症状的关系[J].上海精神医学，2003，15（1）：4-6.
[14]	施永斌，张卫，赵宝龙，等.PANSS、SANS 及 SAPS 量表一致性研究[J].上海精神医学，1999，11（1）：23-25.
[15]	何燕玲，张明园.阳性和阴性综合征量表（PANSS）及其应用[J].临床精神医学，2017，17（6）：35-37.
[16]	Nestor PG，Shenton ME，Wible C，et al.A neuropsychological analysis of schizophrenic thought disorder[J].Schizophr.Res，1998，29（1）：217-225.
[17]	Zakzanis KK.Neuropsychological correlates of positive vs.Negative schizophrenic symptomatology[J].Schizophr Res，1998，29（3）：227-233.