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2017 Vol. 24, No. 10
Published: 2017-04-08
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Influence of Celecoxib on inflammatory cytokines of inflammation model in RAW 264.7 macrophages induced by lipopolysaccharide
PANG Yi-min；GAN Lu；WANG Xian-zhe；SU Qi；GUO Zhe；HE Ping
Objective To investigate the influence of Celecoxib on the secretion of inflammatory cytokines in RAW 264.7 macrophages model induced by lipopolysaccharide(LPS).Methods Mouse RAW 264.7 macrophage was cultured. 24 h after mouse RAW 264.7 macrophage was stimulated by LPS 1 μg/ml,then cell culture medium was collected.NO was tested by using Griess and the content of TNF-α and PGE2was tested by ELISA.Then the RAW 264.7 macrophage inflammation model was established.The toxic effect of celecoxib on LPS stimulated RAW 264.7 macrophages assayed by MTT.8.00 μmol/L Celecoxib was used to pretreat cell for 1 h,following of 1 μg/ml LPS added to stimulate cell for 24 h. Cell culture medium was collected to test the content of inflammatory factors NO,TNF-α and PGE2in culture medium. Results After 1 μg/ml of LPS stimulated RAW macrophages for 24 h,cell morphology changed obviously,the content of inflammatory factors NO,TNF-α and PGE2in culture medium were obvious higher than those of the control group(P＜0.01).Compared with DMSO control group,8.00 μmol/L Celecoxib group could significantly inhibit the release of inflammatory cytokines NO,TNF-α and PGE2induced by LPS in RAW 264.7 cells(P＜0.01).Conclusion Establishment of LPS induced macrophage model of RAW 264.7 and celecoxib can obvious inhibit the release of inflammatory cytokines NO,TNF-α and PGE2.
2017 Vol. 24 (10): 4-7 [
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Quantitative diagnostic value of real-time ultrasound elastography in rats with obstructive jaundice
MENG Ye；XIAO Yang；LIU Yong；WANG Tao；XI Ke-min
Objective To explore the quantitative diagnostic value of RTE for quantitative analysis of the elasticity of the liver changes in rats with obstructive jaundice.Methods 30 male SD rats(2.5-3.0 months,280-330 g)were randomly divided into group A(experimental group)and group B(control group),15 rats in each group.Rats of the group A was operated to make refolding obstructive jaundice animal model,while group B was only given the sham operation.Ultrasound diagnostic imaging software was used to analyze the elasticity of the liver changes of the animal models preoperative, 2 weeks after the modeling and 2 weeks after the removal of the obstruction;and the diffusion quantitative analysis of the elastic image,the percentage of blue areas(%AREA)and strain mean(MEAN)within the region of interest(ROI)of the rat liver were measured and recorded.The changes of%AREA and MEAN in the two groups were compared at preoperative,2 weeks after the modeling and 2 weeks after the removal of the obstruction.Results There was no significant difference in%AREA and MEAN between the two groups at preoperative and 2 weeks after obstruction relieving(P＞0.05).The AREA and MEAN of group A were 42.60±3.69,93.20±2.54,compared with the group B of 25.40±1.40,108.00± 4.93,the difference was statistically significant(t=6.230,P=0.019;t=4.328,P=0.047).The AREA and MEAN values at 2 weeks after modeling were compared with those at preoperative and 2 weeks after obstruction relieving,the differences were statistically significant(P＜0.05).Conclusion Diffusion quantitative analysis of RTE can reflect the liver changes caused by obstructive jaundice,the MEAN and%AREA in the ROI of the liver after obstructive jaundice may change significantly,which can be used as quantitative indicators of the degree of obstructive jaundice reference.
2017 Vol. 24 (10): 8-11 [
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Research progress in peritoneal dialysis related peritonitis Escherichia coli infection and the expression of aquaporin 1
WANG Cheng-yu；LIAO Yun-hua
Aquaporin 1(AQP1)is a transmembrane channel protein that is expressed in endothelial cells and is involved in transmembrane water transport.AQP1 plays a significant role in the process of peritoneal water transport,and its expression and function on peritoneum have an effect on ultrafiltration of peritoneal dialysis.Peritoneal dialysis is through the peritoneum as a semipermeable membrane to remove urea and creatinine and other toxins and water.Peritoneal dialysis related peritonitis is common for Escherichia coli infection.Peritoneal fibrosis after peritonitis may lead to ultrafiltration failure.In this paper,the significance of the expression of AQP1 in peritoneal dialysis and the latest study of Escherichia coli infection in peritoneal dialysis related peritonitis were reviewed.
2017 Vol. 24 (10): 12-14转18 [
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154
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Research progress of treatment in femoral subtrochanteric fracture
HUANG Gang
Femoral subtrochanteric fracture is common in bone trauma,and mostly occurs in violence or patients suffering form osteoporosis.Due to the speciality of anatomical structure of femoral subtrochanter,to treat the fracture has been tricky all the time in clinic.It is believed that key aspect to treat the fracture is reconstruction of posterior cortex after surgery.With the development of clinical techniques,therapeutic methods for femoral subtrochanteric fracture are always changing in a better effect.The paper reviews the type and treatment of femoral subtrochanteric fracture and explores the current situation of treatment and its development on femoral subtrochanteric fracture aiming at providing some thought for further treatment of femoral subtrochanteric fracture in clinic.
2017 Vol. 24 (10): 15-18 [
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167
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Related factors analysis of mass ascites in elderly patients with HCC after hepatectomy and treatment strategies
XU Jian；LI Jing-dong
Objective To explore the reason and preventing measures of mass ascites in elderly patients with primary hepatocellular carcinoma(HCC)after hepatectomy.Methods Clinical data from 102 elderly HCC patients undergone hepatectomy admitted into our hospital from January 2013 to January 2016 were retrospectively analyzed.According to volume of ascites after surgery,they were divided into mass ascites group and non-mass ascites group.The relevant risk factors of leading to mass ascites after hepatectomy were analyzed and screened.Results There were 19 out of 102 cases occurred with mass ascites.Univariate analysis showed that pre-operative hypoalbuminemia and platelet count,intraoperative blood loss and combination of cirrhosis and portal vein tumor thrombus were associated with postoperative mass ascites(P＜0.05).Multivariate logistic analysis displayed that preoperative hypoproteinemia and thrombocytopenia(＜100× 109/L),and intraoperative blood loss≥600 ml was independent risk factors for postoperative mass ascites(OR= 2.172,2.430,3.985,P＜0.05).Compared with non-mass ascites group,the postoperative observational indexes including extubation time and hospital stay were displayed statistical differences(P＜0.05).Conclusion Analyzing the related factors on the generation of mass ascites in elderly HCC patients after hepatectomy is beneficial to positively prevent and tackle the relevant factors leading to ascites generation during perioperative period,so as to reduce the postoperative incidence and improve patients′prognosis.
2017 Vol. 24 (10): 19-22转26 [
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Comparision of vision improvement efficacy of Simethicone and Dyclonine on the painless gastroscopy
YANG Zhi-wei；WANG Sheng-bing；WANG Fu-qun；LAI Shang-dao；ZENG Xiao-qian；LAN Xia
Objective To compare the vision improvement efficacy of Simethicone Emulsion and Dyclonine Mucilageon in each part of the painless gastroscopy.Methods A total of 240 inpatients and outpatients given painless gastroscopy in our hospital from April to September 2016 were selected as object.All patients were divided into the control group,the Simethicone group and the Dyclonine group in accordance with the random number table method,and each group had 80 patients.The control group did not applicate any mucosal improvement agent.Patients in the Simethicone group were given 20 ml solution which contained 5 ml Simethicone emulsion and 15 ml normal saline orally before 10-15 min endoscopy,while the Dyclonine group was given 10 ml Dyclonine Hydrochloride Mucilage.The visibility under gastroscopy when checking was recorded.Results The rate of manually flush in the control group was 72.50%,which was rather high compared with the simethicone group(21.25%)and the dyclonine group(18.75%)(P＜0.05).The visibility of easophagus and stomach in the Simethicone group and the Dyclonine group was better than the control group(P＜0.01).Compared with the Dyclonine group,the visibility of easophagus in the simethicone group was worse(P＜0.05),but it had no difference in the stomach(P＞0.05).Conclusion The visibility of painless gastroscopy without mucosal improvement agent is bad,and the application of Simethicone Emulsion or Dyclonine Hydrochloride Mucilage is recommended before examination.Both of them can improve the visibility,and reduce the chance of manually flush.The efficacy of Dyclonine Hydrochloride Mucilage is better than Simethicone Emulsion.However,in terms of public health economics,Simethicone Emulsion is more suitable.
2017 Vol. 24 (10): 23-26 [
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203
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Safety and efficacy analysis of invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure
LIU Jian-min
Objective To explore the safety and efficacy of invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure.Methods 64 elderly patients with severe respiratory failure treated in our hospital from December 2014 to March 2016 were selected as study object.Patients were divided into control group and observation group according to random number table method,and each group had 32 cases.The control group was given conventional mechanical ventilation and the observation group was given invasive and non-invasive sequential mechanical ventilation.The blood gas indexes,respiratory(RR)and heart rate(HR),therapeutic time and clinical effect between two groups were compared.Results The PaO2and SpO2in observation group were obviously higher than those in control group,while PaCO2,HR and RR were obviously lower than those in control group(P＜0.05).Total mechanical ventilation time,invasive ventilation time and hospital stay in observation group were shorter than those in control group,and the difference was significant(P＜0.05).Rate of successful weaning in observation group was higher than that of control group,and the rate of reintubation and ventilator associated pneumonia were lower than those of control group(P＜0.05).Conclusion Invasive and non-invasive sequential mechanical ventilation in the treatment of elderly patients with severe respiratory failure has a obvious effect,which with higher safety and is worth to be widely used in clinic.
2017 Vol. 24 (10): 27-29 [
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Clinical study of Mometasone Furoate Cream combined with Calcipotriol Ointment for the treatment of chronic eczema and neurodermatitis
WU Hai-hong
Objective To study the clinical effect of Mometasone Furoate Cream combined with Calcipotriol Ointment in the treatment of chronic eczema and neurodermatitis.Methods A total of 94 patients with chronic eczema and neurodermatitis treated in our hospital were randomly selected as object from August 2014 to August 2015.The patients were divided into two groups according to the method of medication.44 patients given Mometasone Furoate Cream for the control group,while 50 cases based on the control group were given Kalbotriol Ointment for the observation group.Efficacy of different drugs was evaluated.Results After treatment,the lesion area,lesion area score,skin pruritus score and eczema index score,skin physiological function and treatment efficiency of the observation group were statistically significant compared with the control group(P＜0.05).Conclusion Mometasone Furoate Cream combined with Calcipotriol Ointment for the treatment of chronic eczema and neurodermatitis can obviously narrow the target lesion area and reduce the degree of skin lesions,improve the skin itching,the effect is remarkable.
2017 Vol. 24 (10): 30-32 [
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Comparison of the different treatment regimens on patients with hepatitis B and its influence on the disease related indicators
GONG Shi
Objective To observe and compare the antiviral effects of different treatment regimens on patients with hepatitis B and its influence on the disease related indicators.Methods 98 hepatitis B patients treated in our hospital from October 2014 to April 2015 were divided into A group and B group according to random number table,with 49 cases in each group.Patients in A group were used Lamivudine,and the B group were used Lamivudine combined with Adefovir dipivoxil.The total effective rate of antiviral,the platelet index(PLT,PDW and GMP-140),fibrosis index(IV-C,LN and HA)serum expression levels before and after treatment of two groups were detected and compared.Results After treatment for 2,4 and 6 months,the total effective rate of antiviral in B group was respectively 69.39%,83.67%and 91.84%, obvious higher than those of 46.94%,59.18%and 71.43%in A group,PLT at different time after treatment was higher than that in group A,and other platelet index and fibrosis index serum expression levels were lower than those in A group and there were significant differences(P＜0.05).Conclusion The antiviral effect of lamivudine combined with adefovir dipivoxil on hepatitis B patients is significantly better than that of lamivudine alone,and its effect on the disease related indicators is better than lamivudine.Therefore,it is considered to be more valuable in patients with hepatitis B.
2017 Vol. 24 (10): 33-35 [
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Correlation analysis of serum reproductive hormone levels and testicular spermatogenic function of male patients with azoospermia
CHENG Guo-long；SONG Rong
Objective To explore correlation of serum reproductive hormone levels and testicular spermatogenic function of male patients with azoospermia.Methods 144 cases of patients who were diagnosed in hospital from March 2013 to March 2016 were selected,and 94 cases of patients with azoospermia were selected as experimental group and 50 cases of fertile healthy men were selected as the control group.The patients in the experimental group were divided into group A(31 cases without sperm group)and group B(63 cases with sperm group).The difference of semen routine and serum reproductive hormone level,and the correlation of testicular spermatogenesis function were compared.Results FSH and LH of group A were significantly higher than those of control group,while the testosterone level was lower than that of control group(P＜0.05).There was no significant difference in hormone levels between group B and the control group(P＞0.05).FSH,LH hormone levels and testicular spermatogenesis showed a negative correlation results(FSH:r=-0.572,P= 0.000;LH:r=-0.431,P=0.000),testosterone T and testicular spermatogenic function was positively correlated(r=0.313,P= 0.014).PRL,E2had no correlation with testicular spermatogenic function.Conclusion FSH is closely related to azoospermia and can be used as a predictor of pre-testicular puncture.It is of great significance for the treatment of azoospermia and deserves further study.
2017 Vol. 24 (10): 36-38 [
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The clinical effect observation of hyperbaric oxygen coupled with compound musk injection on diffuse axonal injury
LI Liang；HE Jia-jun；HUANG Shan-lin
Objective To observe the effect of hyperbaric oxygen(HBO)combined with compound musk injection on the treatment of diffuse axonal injury(DAI)and the effect of arousal.Methods The patients from September 2014 to June 2016 in our hospital with diffuse axonal injury in 42 cases were randomly divided into two groups,21cases in experimental group were treated with hyperbaric oxygen combined with compound musk injection treatment,while the control group was treated with hyperbaric oxygen therapy,and in 6 months after treatment,the two groups of patients was compared with awareness of the situation improved,and Glasgow outcome score(GOS)to evaluate the curative effect and prognosis.Results Compared with the control group(28.57%),the cure rate of the experimental group(52.38%)was higher,the difference was statistically significant(P＜0.05).Compared with the control group(71.00%),the awake rate of the experimental group(90.47%)was significantly higher;the awake time of of the experimental group[(17.44±10.22)d]was shorter than that of the control group[(24.37±11.56)d]，and the differences were statistically significant(P＜0.05).Compared with the control group,the recurrent rate and complication rate in the experimental group(10.00%,14.00%)were significantly higher than those in the control group(33.00%,43.00%),the differences were statistically significant(P＜0.05). The curative effect was significant.Conclusion The curative effect of patients with diffuse injury of shrinkage is good, which can increase the patients improve patients'life quality and outcomes.
2017 Vol. 24 (10): 39-41 [
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191
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Effect of community rehabilitation on remission of elderly patients with chronic obstructive pulmonary disease
LI Chang-qing
Objective To explore the effect of community rehabilitation in remission of elderly patients with chronic obstructive pulmonary disease.Methods A total of 112 elderly patients with chronic obstructive pulmonary disease(COPD) were enrolled in this study from July 2014 to February 2016 in Guangming New District People′s Hospital.All patients were divided into control group and observation group.There were 56 patients in each group.Routine therapy was given to the control group.The observation group was given community rehabilitation and the treatment effect was compared between the two groups.Results After 1 year,The levels of FVC and FEV1/FVC of patients in the observation group [（1992.58±33.15）ml,(72.33±5.32)%]were higher those in the control group[（1736.52±31.48）ml,（63.68±2.25）%];The SGRQ score of patients in the observation group[（37.86±2.24）points]was lower than that in the control group[（46.14± 2.82）points];The number of acute attack in the observation group was significantly lower than that in the control group. All the differences were statistically significant(P＜0.05).Conclusion It has significant effect on community rehabilitation in elderly patients with COPD.It can significantly improve the quality of lung function and the quality of life,inhibit the deterioration of the disease and improve the prognosis.It is worthy of clinical promotion.
2017 Vol. 24 (10): 42-44 [
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Efficacy and safety of Shuxuetong Injection combined with Isosorbide Mononitrate in the treatment of unstable angina pectoris
ZHANG Rong-hua；HUANG Chao-fa；HUANG Xiao-rong；ZHENG Gui-ying
Objective To study the efficacy and safety of Shuxuetong Injection combined with Isosorbide Mononitrate in the treatment of unstable angina pectoris(UAP)of coronary heart disease(CHD).Methods 56 patients with UAP of CHD who were treated in our hospital from August 2014 to August 2016 were selected and randomly divided into the control group and the observation group,28 cases in each group.The control group was treated with Shuxuetong Injection ,the observation group was treated with Shuxuetong Injection combined with Isosorbide Mononitrate Injection.The levels of Alanine aminotransferase(ALT),fibrinogen(FIB)and serum creatinine(SCr)and clinical efficacy were compared between the two groups before and after treatment.Results The total effective rate of the observation group was 92.86%, which was higher than that of the control group(71.43%),with significant difference(P＜0.05).The level of FIB after treatment in the observation group was lower than that before treatment and in the control group,with significant difference(P＜0.05).There was no significant difference in the level of ALT and SCr after treatment between the observation group and the control group(P＞0.05).Conclusion The effect of Shuxuetong Injection and Isosorbide Mononitrate Injection in the treatment of UAP of CHD is significant,which is worthy of promotion.
2017 Vol. 24 (10): 45-47 [
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Clinical observation of Rosuvastatin combined with Probucol in the treatment of atherosclerosis
ZOU Yan-ming；YAO Yuan-ying；LI Rong；XIN Hui
Objective To obsreve the effect of Rosuvastatin combined with Probucol in the treatment of atherosclerosis. Methods 180 cases of coronary heart disease from January 2013 to June 2015 treated in our hospital were selected and randomly divided into the combination group,the Rosuvastatin group and the Probucola group,60 cases in each group. All of them were treated for 6 months.The combined group was treated with Rosuvastatin combined with Probucol Tablets,the Rosuvastatin group was only given Rosuvastatin,the Probucol group was only given Probucol.The effective rate of each group was measured,the levels of serum cholesterol,high density lipoprotein and low density lipoprotein were detected,and the intima-media thickness of carotid artery was calculated.The therapeutic effects of the three groups were evaluated.Results The total effective rate of the combined group was significantly higher than that of the Rosuvastatin group and the Rrobucol group,with significant difference(P＜0.05).There was no significant difference in total effective rate between the Rosuvastatin group and the Probucol group(P＞0.05).There was significant difference in the levels of total cholesterol,high-density lipoprotein,low-density lipoprotein and carotid intima-media thickness of thecombined group before and after treatment(P＜0.05).There was significant difference in the level of serum total cholesterol and high density lipoprotein cholesterol before and after treatment in the Rosuvastatin group(P＜0.05).There was significant difference in the level of low density lipoprotein and carotid intima media thickness in the Probucol group before and after treatment(P＜0.05).There was significant difference in the level of low density lipoprotein and carotid intima media thickness after treatment between the combined group and the Rosuvastatin group(P＜0.05).There was significant difference in the level of the total cholesterol,high density lipoprotein and carotid intima-media thickness after treatment between the combined group and the Probucol group(P＜0.05).There were significant differences in the level of total cholesterol,high density lipoprotein,low density lipoprotein and carotid intima media thickness after treatment between the Rosuvastatin group and the Probucol group(P＜0.05).Conclusion Rosuvastatin conbined with Probucol can effectively inhibit atherosclerosis,compared with a single drug,which can significantly improve the efficacy,it is worthy of promotion and application in clinical practice.
2017 Vol. 24 (10): 48-52 [
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Clinical efficacy of Valsartan combined with Hydrochlorothiazide in the treatment of senile hypertension and its influence on blood pressure variability
LI Jing
Objective To investigate the clinical efficacy of Valsartan combined with Hydrochlorothiazide in the treatment of senile hypertension and its influence on blood pressure variability(BPV).Methods 90 patients with senile hypertension who treated in our hospital from March 2015 to March 2016 were selected and divided into the observation group and the control group by admission order,45 cases in each group.The control group was treated with Valsartan,the observation group was treated with Hydrochlorothiazide on the basis of the control group.The clinical efficacy and BPV of the two groups were analyzed.Results The total effective rate of the observation group was higher than that of the control group,with significant difference(P＜0.05).The detection results of 24 h diastolic blood pressure variability(24 h DBPV)and 24 h systolic blood pressure variability(24 h SBPV)after treatment in the observation group was better than that in the control group,with significant difference(P＜0.05).The level of 24 h SBP and 24 h DBP after treatment in the observation group was better than that in the control group,with significant difference(P＜0.05).Conclusion Valsartan combined with Hydrochlorothiazide in the treatment of senile hypertension have definite curative effects,it can increase blood pressure control,decrease BPV and have higher application value.
2017 Vol. 24 (10): 53-55 [
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Analysis of related factors of epilepsy complicated with mood disorder
HUANG Bo；LI Chun
Objective To investigate the related influence factors of epilepsy complicated with mood disorder.Methods Altogether 60 epilepsy patients treated in outpatient department of neurology of Brain Hospital of Guangxi Zhuang Autonomous Region from January 2014 to December 2015 were involved as epilepsy group,and 50 cases of healthy persons who accepted health examinations at the same period was involved as control group.The general conditions,the clinical features,self-rating depression scale(SDS)and the self-rating anxiety scale(SAS)of two groups were observed.Pearson correlation analysis of SDS,SAS and clinical features and Logistic regression analysis of SDS and SAS of two groups were also observed.Results Two groups had no significant difference in gender,marital status and educational background(P＞0.05).The proportion of relatively low brain 5-HT power was lower than that of normal brain 5-HT power,the proportion of seizure frequency≤2 times/year was higher than that＞2 times/year,and the proportion of use of＞2 antiepileptic drugs was higher than that of single drug(χ2=48.74,50.00,22.31，P＜0.05).SDS and SAS score of epilepsy group were higher than those of control group(t=11.50,12.36,P＜0.05).Epilepsy patients′SAS score showed a positive correlation with the number of antiepileptic drugs(r=0.328,P＜0.05),and SDS score was positively correlated with seizure frequency and course of disease,negatively correlated with brain 5-HT power(r=0.209,0.214,-0.189,P＜0.05);the number of antiepileptic drugs was the influencing factors of epilepsy patients′anxiety(χ2=11.024,P＜0.01);and the seizure frequency,course of disease,brain 5-HT power were the influence factors of epilepsy patients′depression(χ2=10.697,10.789,-11.052,P＜0.01),with statistically significant difference.Conclusion The more antiepileptic drugs the epilepsy patients take,the more possibility the anxiety will occur;the more epilepsy seizures,the longer course of disease,the lower brain 5-HT power,the more possibility the depression will occur.
2017 Vol. 24 (10): 56-58转61 [
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Clinical effect analysis of Argatroban combined with Clopidogrel in the treatment of large-artery atherosclerosis-induced cerebral infarction
YANG Yu-hua
Objective To evaluate the clinical effect of Argatroban combined with Clopidogrel in the treatment of largeartery atherosclerosis-induced cerebral infarction.Methods A total of 74 patients with large-artery atherosclerosis-induced cerebral infarction treated by our hospital from April 2015 to August 2016 were selected as research objects. Based on randomization,they were divided into control group(n=37)and observation group(n=37).In the control group, Clopidogrel was used,on the basis,Argatroban was added in the observation group.The neurologic impairment,activity of daily living,inflammatory factor levels,and occurrence of adverse reactions before and after treatment in two groups were observed.Results In the observation group,the scores of neurologic impairment and activity of daily living were(4.71±0.63) points and(81.82±2.33)points after treatment.The levels of interleukin-8 and tumor necrosis factor-α were(0.36±0.28) ng/ml and(0.40±0.19)ng/ml,which were all superior to those in the control group with statistical differences(P＜0.05). Difference in incidence rate of adverse reactions was not great(P＞0.05).Conclusion Argatroban combined with Clopidogrel in the treatment of large-artery atherosclerosis-induced cerebral infarction can remarkably improve the neurologic impairment and activity of daily living in high safety.
2017 Vol. 24 (10): 59-61 [
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Clinical effect of head mild hypothermia in treating hypertensive cerebral hemorrhage
FANG Hao-wei；LIN Han；YU Ying-li；HUANG Xiao-yun；WANG Ming-xia
Objective To explore the clinical effect of head mild hypothermia treating hypertensive cerebral hemorrhage. Methods 110 patients with hypertensive cerebral hemorrhage treated by our hospital from February 2014 to February 2016 were selected and divided into observation group(n=55)and control group(n=55).The control group was given general treatment,and the observation group was given head mild hypothermia.The clinical effect between two groups was compared.Results The intracranial pressure had no significant difference between two groups before treatment(P＞0.05), after treatment for 1,2,5 and 7 days,the intracranial pressure in the observation group was obviously lower than those of control group,and the difference was significant(P＜0.05).The total incidence rate of complications in the observation group was 10.91%,and it was obviously lower than that was 32.73%in the control group,and the difference was significant (χ2=7.674,P=0.006).Before treatment,the GCS and NIHSS score between two groups had no significant(P＞0.05),after treatment for 2 weeks,the GCS score in the observation group was obviously higher than that of control group,while NIHSS score was obviously lower than that of control group,and the difference was significant(P＜0.05).The total effective rate of daily life ability score in the observation group was 92.7%,and it was obviously higher than that in control group (76.4%),and the difference was significant(χ2=5.636,P=0.018).Conclusion Head mild hypothermia treating hypertensive cerebral hemorrhage can effectively reduce the intracranial pressure and incidence rate of complications,improve neurological deficit and prognosis,reduce the mortality of patients and it is worthy of clinical promotion and application.
2017 Vol. 24 (10): 62-64 [
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Clinical effect of intravenous thrombolysis treating senile acute cerebral infarction
FANG Ming；ZHANG Tian
Objective To explore the clinical effect of intravenous thrombolysis treating senile acute cerebral infarction. Methods 92 senile acute cerebral infarction patients from October 2014 to October 2016 treated in our hospital were selecetd and divided into control group and treatment group according to random number table method,and each group had 46 cases.The control group was given general antiplatelet therapy,the treatment group was given intravenous thrombolysis with recombinant tissue plasminogen activator.The neurological function recovery time and the total treatment time,the incidence rate of adverse reactions,the total effective rate,neurological deficit score and Barthel score before and after treatment between two groups were compared.Results The neurological function recovery time and the total treatment time in treatment group were shorter than control group,and the difference was obvious(P＜0.05).The incidence rate of adverse reaction in treatment group(2.2%)was lower than that was 19.6%in control group(P＜0.05).The total effective rate of(91.3%)treatment group was higher than that was 71.7%in control group,and the difference was obvious between two groups(P＜0.05).Before and after treatment,the improvement range of neurological deficit score and Barthel score were higher than control group,and the difference was significant(P＜0.05).Conclusion intravenous thrombolysis for senile acute cerebral infarction patients can make the nerve function to get a substantial improvement in a short time,reduce the possibility of adverse drug reactions and improve the safety and the total effective rate of treatment.
2017 Vol. 24 (10): 65-67 [
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Clinical effect of percutaneous nephrolithotomy with renal access created by modified B ultrasound guided two-step dilation in the treatment of nonhydronephrosis renal calculus
LIU Fo-lin；ZOU Yu-hua；XU Rui-quan；YUAN Yuan-hu▲；WU Geng-qing；XIE Kun-lin
Objective To investigate the method and safety of percutaneous nephrolithotomy(PCNL)with renal access created by modified B ultrasound guided two-step dilation in the treatment of non-hydronephrosis renal calculus,and to evaluate its clinical value.Methods From January to December in 2016,80 patients with non-hydronephrosis renal calculus in our hospital were selected and randomly divided into group A and group B,40 cases in each group.Group A was treated with PCNL with renal access created by modified B ultrasound guided two-step dilation,group B was treated with PCNL with conventional B ultrasound guided gradual dilation.The success rate of renal access,renal access creation time,operation time,the average blood loss,hospitalization time,the calculus clearance rate and the incidence rate of complications between the two groups were analyzed and compared respectively.Results There was no significant difference between A group and B group in the stone clearance rate and hospital stay(P＞0.05).The success rate of group A was higher than that of group B,channel establishment time,operation time of group A was shorter than that group B, the blood loss of group A was less than of group B,with significant difference(P＜0.05).There was no significant difference in the incidence rate of complications between the two groups(P＞0.05).Conclusion PCNL with renal access created by modified B ultrasound guided two-step dilation in the treatment of non-hydronephrosis renal calculus is safe and feasible,the effect is significant,it has some advantages of simple channel,high success rate,shorter operation time and less bleeding,it is worthy of promotion.
2017 Vol. 24 (10): 68-71 [
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151
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72
Application of endoscope-assisted catheter in the treatment of bulbar urethral rupture
HE Ling-sheng；DENG Shao-zhen；LI Yan-fen
Objective To explore and analyze the effect of application of endoscope-assisted catheter in the treatment of bulbar urethral rupture.Methods Altogether 60 patients with bulbar urethral fracture who accepted clinical treatment from November 2013 to November 2016 in our hospital were selected as the object of this research and divided into the control group and the experiment group according to the random number table method,with 30 patients in each group. The control group was treated with open surgery,while the experiment group was treated with endoscopic-assisted catheter.The curative effect of the two groups was compared.Results There was no significant difference in the surgical success rate and urine flow rate between the experiment group and the control group(P＞0.05).The amount of bleeding in the experiment group was less than that in the control group,and the operation time and hospital stay in the experiment group was shorter than that in the control group,with significant difference(P＜0.05).The treatment total satisfaction degree of the experimental group was 96.67%,which was higher than that of the control group(73.33%),with significant difference(P＜0.05).Conclusion Application of endoscope-assisted catheter in the treatment of patients with bulbar urethral rupture delivers obviously better curative effect than open surgeries.
2017 Vol. 24 (10): 72-74 [
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150
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Clinical effect of traditional Chinese medicine bone-setting in the treatment of distal radius fractures
YUAN Guo-hua；HUANG Xiao-lin
Objective To evaluate the clinical effect of traditional Chinese medicine(TCM)bone-setting in the treatment of distal radius fractures.Methods 100 cases with were distal radius fractures in our hospital from June 2013 to June 2016 were selected and randomly divided into the control group and the observation group,50 cases in each group. The control group was given the traditional traction reduction and plaster fixation,the observation group was treated with TCM bone-setting and small splint external fixation.The time of wrist swelling,the time of complete pain relief,the time of fracture healing,the length of hospital stay,the recovery of wrist function and the incidence rate of complication were compared between the two groups.Results The swelling subsided time,perceived pain complete remission time,fracture healing time and length of stay of the observation group was shorter than that of the control group,with significant difference(P＜0.05).The excellent and good rate of wrist joint function recovery in the observation group was higher than that in the control group,with significant difference(P＜0.05).The incidence tare of complications in the observation group was lower than that in the control group,with significant difference(P＜0.05).Conclusion TCM bone-setting has a good curative effect on distal radius fracture,combined with early functional exercise，which can help the patients to improve symptoms,promote the recovery of wrist function.
2017 Vol. 24 (10): 75-77 [
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160
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Effect analysis of reconstruction of plate internal fixation in the treatment of middle clavicle fracture
BAI Yang-ping；LIN Qing-pei；LUO Wei-chu；DAI Gao-wei；LIN Qin-yi
Objective To explore the effect of reconstruction of plate internal fixation in the treatment of middle clavicle fracture.Methods Clinical data of 54 patients with middle clavicle fractures treated in Department of Orthopedics in our hospital from January 2013 to December 2015 were retrospectively analyzed.According to different surgical modes,they were evenly divided into the control group and the observation group,27 cases in each group.In the control group, Kirschner wire tension band for fixation was used,while in the observation group,reconstruction of plate internal fixation was adopted.The surgical effect,operation time,intraoperative amount of bleeding,hospital stay,healing time of bone fracture,and the incidence rate of postoperative complications in the two groups were compared.Results The excellent and good rate of surgery in the observation group was 96.30%,which was higher than that in the control group(74.07%),with significant difference(P＜0.05).The operation time,hospital stay,and healing time of bone fracture in the observation group was shorter than that in the control group,intraoperative amount of bleeding in the observation group was less than that in the control group,with significant difference(P＜0.05).The incidence rate of complications such as screw loosening,fracture displacement,malunion and scapulohumeral periarthritis in the observaiton group was lower than that in the control group,with significant difference(P＜0.05).Conclusion Reconstruction of plate internal fixation is effective in the treatment of middle clavicle fracture at advantage of simple and easy on performance,high safety,quick bone heal, and low incidence rate of complications,which has positive clinical significance.
2017 Vol. 24 (10): 78-80 [
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180
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Clinical effect and safety analysis of small incision minimally invasive in the treatment of fresh rupture of achilles tendon
LIN Lang-shan；CHEN Feng；YANG Zheng-lu；LIU Jun
Objective To analyze the clinical effect and safety of small incision minimally invasive in the treatment of fresh rupture of achilles tendon.Methods 120 patients with fresh rupture of achilles tendon from March 2013 to June 2016 in our hospital were selected and randomly divided into the observation group and the control group,60 cases in each group.The observation group was given small incision minimally invasive and the control group was treated with general incision.The treatment effect of the two groups was compared.Results The incidence rate of postoperative complications in the observation group was 5.00%,which was lower than that of the control group(20.00%),with significant difference(P＜0.05).The complete recovery time and hospitalization time in the observation group was shorter than that in the control group,and the difference of the maximum circumference between the two sides of the observation group was less than that of the control group,with significant difference(P＜0.05).The total effective rate of the observation group was 93.33%, which was higher than that of the control group(75.00%),with significant difference(P＜0.05).Conclusion Using small incision minimally invasive in the treatment of fresh rupture of achilles tendon can not only reduce the complications such as infection,tendon rupture,adhesion after operation,but also improve the perimeter difference of bilateral crus, shorten the recovery time and hospitalization time.
2017 Vol. 24 (10): 81-83 [
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176
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84
Effect observation of open reduction and internal fixation in the treatment of ankle fracture
ZHANG Shao-feng；FANG Xiang-zi；LI Jia-mei；HUANG Xue-zhang；LI Yin-ying；LIANG Su-juan；ZHONG Hui-mei
Objective To observe and evaluate the effect of open reduction and internal fixation in the treatment of ankle fracture.Methods A total of 84 patients with displaced ankle fractures treated in our hospital from June 2014 to June 2016 were selected as observation objects.According to the random number table method,they were divided into the research group and the control group,42 cases in each group.In the control group,patients with ankle joint fractures were treated with traditional plaster for external fixation.In the research group,open reduction and internal fixation was applied.The excellent and good rate after therapy,ankle function recovery and the occurrence of complications were compared in the two groups.Results The excellent and good rate in the research group was 97.62%,which was higher than that in the control group(83.33%),with significant difference(P＜0.05).The scores of pain,ankle stability,walking ability,running ability,work ability,range of motion and radiological results in the research group was higher than that in the control group,with significant difference(P＜0.05).The incidence rate of complications in the research group was 4.76%,which was lower than that in the control group(19.05%),with significant difference(P＜0.05).Conclusion The effect of open reduction and internal fixation in the treatment of ankle fracture is remarkable,which can effectively improve the ankle function of the patients with ankle fractures and it is worthy of clinical promotion and application.
2017 Vol. 24 (10): 84-86 [
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149
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The changes of T lymphocytes sub-types and NK cells in patients with unexplained recurrent abortion
MA Chao；FENG Wen-hua
Objective To explore the changes of T lymphocytes sub-types and NK cells in patients with unexplained recurrent abortion.Methods The patients were collected in the Liaoning Province Research Institute of Family Planning from March 2014 to March 2016.The 50 patients with URSA were selected as the observation group and 30 patients with voluntary abortion were selected as the control group.Flow cytometry was used to measure the number of T lymphocytes sub-types and NK cells in the two groups.Results The percentages of CD4＋and ratio of CD4＋/CD8＋was significantly increased in peripheral blood of unexplained recurrent abortion patients(P＜0.05),while there was no significantly differences in CD3＋and CD8＋(P＞0.05).The level of NK cell was also significantly increased in peripheral blood of unexplained recurrent patients(P＜0.05).Conclusion The increasing level of CD4＋,CD4＋/CD8＋and NK cells in peripheral blood of recurrent abortion patients is harmful to maintain pregnancy even induced abortion.
2017 Vol. 24 (10): 87-89 [
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136
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Study on the control of body mass index in gestational diabetes mellitus under the new standard
ZHANG Ming-fang；WU Shan；DAI Hong-chun
Objective To study the clinical significance of body mass index(BMI)in gestational diabetes mellitus(DM). Methods 62 cases of gestational diabetes patients in our hospital from July 2015 to July 2016 for regular antenatal examination and hospital delivery were randomly selected,according to the BMI index of different pregnancy all the patients were divided into low body weight group(10 cases)and normal group(24 cases),overweight group(15 cases)and obesity group(13 cases).In addition,according to the BMI index increase of all patients before pregnancy to pregnancy, the patients were divided into group A(n=19),group B(n=22)and group C(n=11).The incidence of pregnancy complications and the incidence of adverse pregnancy outcomes were observed and analyzed,and the clinical significance of gestational diabetes mellitus during pregnancy was also discussed.Results Pregnancy complications in patients with normal weight group was 12.50%,the incidence of adverse pregnancy outcomes was 4.17%,significantly lower than the low body weight 50.00%,30.00%and 40.00%,33.34%overweight and obesity were 61.54%and 53.85%.The complication rate of group B was 16.00%,and the incidence of adverse pregnancy outcomes was 4.00%,which was significantly lower than that of group A(45.46%,36.36%),and group C(53.33%,46.67%),the differences were statistically significant(P＜0.05). Conclusion BMI and gestational diabetes mellitus patients BMI greater growth rate,pregnancy complications,the incidence of adverse pregnancy outcome probability is higher,therefore,told gestational diabetes during pregnancy BMI control has important clinical significance.
2017 Vol. 24 (10): 90-92 [
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166
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Analysis of 2614 male pre-pregnancy eugenic health examination results
ZUO Lian-dong；QU Yan-xia；TANG Lin-guo
Objective To analyze the male pre-pregnancy eugenic health examination results in order to explore the adverse factors affecting reproductive health.Methods The examination results of 2614 men accepted free pre-pregnancy eugenic health examinations from January 2013 to December 2015 in Guangzhou Women and Children Medical Center（the primary name was Guangzhou Institute of Population and Family Planning）were analyzed.Results The adverse health factors in male pre-pregnancy eugenic health examination accounted for 70.63%，among which the top four factors included reproductive system disorders（phimosis，varicocele，epididymis abnormality），more than 1 positive in Hepatitis B virus（HBV）test（except for HBsAb），increased alanine aminotransferase（ALT）and urine abnormality，accounted for 35.85%，25.78%，17.48%and 16.37%respectively.Conclusion In the pre-pregnancy eugenic examinations，the male reproductive health adverse conditions have being warried.More attention should be paid to the importance of male participation in pre-pregnancy examination，which promotes eugenics.
2017 Vol. 24 (10): 93-95 [
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148
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Clinical study of combination of application of Recombinant Human Interferon α2b Suppositories and Nifuratel Nystatin Soft Capsules in treatment of recurrent vulvovaginal candidiasis
XU Xiao-xian；LI Shi-rong；WU Hui-yin
Objective To investigate the effect of combination of application of Recombinant Human Interferon α2b Suppositories and Nifuratel Nystatin Soft Capsules in the treatment of recurrent vulvovaginal candidiasis(RVVC). Methods Altogether 120 patients with RVVC who were treated in our hospital from May 2015 to April 2016 were randomly divided into observation group and control group,with 60 cases in each group.The control group was treated with the combination of Nifuratel Nystatin Soft Capsules and Fluconazole Dispersible Tablets;while,observation group was treated with the combination of recombinant human interferon α2b Suppositories and Nifuratel Nystatin Soft Capsules.The curative effect of the two groups were observed.Results The total effective rate of observation group was 96.7%,higher than that of control group(71.7%)(P＜0.05);the adverse reaction rate of observation group and control group were 1.7%and 11.7%,with statistically significant difference(P＜0.05);the 3-month and 6-month after drug withdrawal recurrence rate of observation group were 0 and 3.3%,significantly lower than those of control group(10.0%,25.0%)(P＜0.05).Conclusion Combination of application of Recombinant Human Interferon α2b Suppositories and Nifuratel Nystatin Soft Capsules in the treatment of recurrent vulvovaginal candidiasis is helpful to improve the therapeutic effect and reduce the adverse reactions and recurrence rate,which achieves obvious curative effect.
2017 Vol. 24 (10): 96-98 [
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150
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Comparison of application of oxygen and carbon dioxide pneumoperitoneum in the laparoscopic high ligation of hernial sac in children
ZHONG Fei；GUO Zhen-yu；ZHONG Xiang
Objective To compare the effect of oxygen and the carbon dioxide pneumoperitoneum in the laparoscopic high ligation of hernial sac in children.Methods 200 cases of children with inguinal hernia(less than or equal to 8 years old)from February 2010 to July 2016 in the People′s Hospital of Dayu County were randomly divided into group A and group B,with 100 cases in each.Group A was given oxygen,and the group B was given carbon dioxide pneumoperitoneum for single port high ligation of the hernial sac.The changes of pH,partial pressure of oxygen(PaO2),carbon dioxide partial pressure(PaCO2),heart rate(HR),body temperature at previous 5 min,10 min after pneumoperitoneum,and 30 min after pneumoperitoneum were compared between the two groups,as well as the postoperative recovery time and complication rates.Results The changes of pH values,PaO2,PaCO2,HR and body temperature at 10 min after pneumoperitoneum,and 30 min after pneumoperitoneum between the two groups has significant differences(P＜0.05).The postoperative recovery time in the group A was significantly shorter than that in the group B(P＜0.05).The complication rate in the group A was far lower than that in the group B(P＜0.05).Conclusion The effect of oxygen pneumoperitoneum in laparoscopic high ligation of hernial sac in children than in the traditional carbon dioxide pneumoperitoneum is better,which can stabilize the blood gas index,but also can shorten the postoperative recovery time and reduce complications.
2017 Vol. 24 (10): 99-101转105 [
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126
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The relationship between reproductive tract infection and premature rupture of membranes and its effect on pregnancy outcome
FENG Ying
Objective To investigate the relationship between reproductive tract infection and premature rupture of membranes and its impact on pregnancy outcome.Methods 100 cases of premature rupture of membranes were selected as the study group from May 2015 to November 2016 in our hospital.100 cases of premature rupture of membranes were selected as the control group.The cervical secretions and vaginal secretions were examined for two groups.The pregnancy outcomes of the two groups,chlamydia,mycoplasma,fungal,bacterial vaginosis and trichomoniasis were observed;the pregnancy outcomes of pregnant women of the two groups were compared;the pregnancy outcomes of different types of pregnant women were compared.Results The infection rate of mold,Trichomoniasis,Mycoplasma,bacterial vaginosis and Chlamydia in the study group was significantly higher than that in the control group,the difference was statistically significant(P＜0.05).The incidence of premature delivery,neonatal pneumonia,chorioamnionitis,puerperal infection in the study group was higher than that in the control group,the difference was statistically significant(P＜0.05).The incidence of preterm delivery,neonatal pneumonia,chorioamnionitis was significantly higher in Mycoplasma positive pregnant women than that in negative pregnant women;the incidence of preterm delivery,neonatal pneumonia,chorioamnionitis,puerperal infection and neonatal asphyxia was significantly higher in Chlamydia positive pregnant women than that in negative pregnant women;the incidence of prematurity,neonatal pneumonia,chorioamnionitis and puerperal infection was significantly higher in mold-positive pregnant women than that in negative pregnant women;pregnant women with bacterial vaginitis had a higher incidence of preterm delivery,puerperal infection,neonatal pneumonia and chorioamnionitis than those without bacterial vaginitis;the incidence of neonatal pneumonia,puerperal infection,premature delivery and chorioamnionitis was significantly higher in trichomonas-positive pregnant women than in trichomonas-negative pregnant women,the differences were statistically significant(P＜0.05).Conclusion Premature rupture of membranes can be induced by genital tract infection,which may increase the risk of premature rupture of membranes,it affects the outcome of pregnancy.
2017 Vol. 24 (10): 102-105 [
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136
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Analysis of urine pH in different pathogenoic bacteria of urinary tract infection in children
LIU JingLENG QianLU Biao
Objective To investigate the distribution of common pathogenic bacteria of urinary tract infection in children and clinical characteristics of urine pH value.Methods A retrospective analysis of 180 cases of UTI in urine culture positive results and urine pH in children from September 2015 to September 2016,the distribution of UTI pathogenic bacteria and the clinical characteristics of urine pH was explored.Results Among 180 clinical isolates collected from midstream urine specimens of children in pediatrics,109 cases(61%)were gram-positive organisms,urine pH at 6.3±0.2; 60 cases(33%)were gram-negative organisms,urine pH at 6.2±0.1,while 11 cases(6%)were fungi,urine pH at 5.2±0.3.pH was compared among three kinds of children with different pathogenic bacterial infection,urine of children with fungal infection with higher pH value,and the differences were statistically significant(P＜0.05).Conclusion Corresponding to different pathogenic bacteria of urinary infections in children′s urine pH distribution rang is different,the growth of pathogenoic can be effectively inhibited through adjusting of the urine pH,and improve the efficacy of antibacterial.
2017 Vol. 24 (10): 106-108 [
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128
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Application effect of cervical dilatation balloon in cervical ripening and labor induction of pregnant women
ZHANG Xiao-lin
Objective To investigate the application effect of cervical dilatation balloon in cervical ripening and labor induction of pregnant women.Methods 140 pregnant women with single head position of having labor induction indicators and intact fetal membrane from January 2015 to June 2016 in our hospital were selected as research object,and they were divided into observation group and control group by random number table,70 cases in each group.Control group took controlled release of dinoprostone suppositories,observation group took cervical dilatation balloon.The cervical ripening effects,Bishop scores and delivery outcomes of two groups were compared.Results The total effective rate of cervical ripening of observation group was 95.71%,which was significantly higher than 77.14%of control group(P＜0.01);before the using of cervical dilatation balloon,there was no statistical difference in Bishop scores between two groups(P＞0.05);the Bishop scores of two groups were significantly decreased after the using of cervical dilatation balloon,and descend tendency of observation group was more significant(P＜0.01);compared with the control group,the rate of natural delivery of observation group was higher,and the incidence of fetal distress,neonatal asphyxia,meconium-staining amniotic fluid was lower(P＜0.05).Conclusion Cervical dilatation balloon is beneficial to cervical ripening and has significant effects,it can increase success rate of labor induction and improve delivery outcomes,which is worthy of clinical application.
2017 Vol. 24 (10): 109-111 [
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151
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Relationship between B Streptococcus infection and missedabortion in reproductive tract
KE Jian；LIN Fu-bing；WU Xiao-juan
Objective To explore the relationship between reproductive tract B Streptococcus infection and missed abortion.Methods 40 patients with missed abortion from January 2015 to October 2016 in our hospital were selected as the study group,40 cases of normal pregnancy were selected as the control group in the same period.The two groups of members of the vaginal secretions,intrauterine aspirates,amniotic fluid B group hemolytic streptococcus culture,and detecting the possibility of other pathogenic factors were compared.Results Compared with the control group,the vaginal secretions of the study group and the group B streptococcus of the uterine cavity aspirate had no statistically significant difference.The positive rates of Mycoplasma,Mycoplasma hominis and Mycoplasma parahaemolyticus were higher in the study group than those in the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the positive rate of Mycoplasma infection,Chlamydia infection and chlamydia antibody among the B group hemolytic streptococcus between the observation group and the control group(P＞0.05).Conclusion There is no direct re lationship between the infection of B group hemolytic streptococci in the reproductive tract and the early abortion and midinduced abortion.Therefore,there is no need for premature intervention of genital tract B Streptococcus infection pregnant women.But whether there is an indirect relationship between the two,you need further study.
2017 Vol. 24 (10): 112-114 [
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122
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Effect of estradiol valerate combined with vitamin E on the vaginal wall of postmenopausal uterine prolapse surgery
GAO Hai-yan
Objective To investigate the effect of estradiol valerate combined with vitamin E on vaginal wall of postmenopausal uterine prolapse surgery.Methods 60 patients with postmenopausal uterine prolapse admitted to our hospital from March 2014 to September 2016 were selected as study object.They were randomly divided into two groups with a total of 30 cases in each group by random number table method.Among them,30 patients underwent direct uterine prolapse surgery(vaginal hysterectomy＋vaginal wall repair surgery)for treatment were served as control group,and the other 30 patients underwent preoperative estradiol valerate combined with vitamin E and uterine prolapse surgery for treatment were served as the observation group.Endovaginal condition,treatment condition,complication and quality of life,etc.of patients in two groups were observed.Results The level difference for MI,KI,VHS,vaginal mucosal thickness, FSH and E2for patients in two groups before treatment were compared with no difference(P＞0.05),the difference was statistically significant between two groups after treatment(P＜0.05).There was no statistical difference in control group before and after treatment besides VHS(P＞0.05);there were significant differences in observation group before and after treatment for all indexes(P＜0.05).There was no significant difference between the two groups for endometrial thickness (P＞0.05).After 1 week of the operation,there was no significant difference in the life quality for patients in two groups (P＞0.05).After 1,3 months of the operation,the life quality score of observation group was significantly higher than that of control group and the difference was statistically significant(P＜0.05).Conclusion When patients with postmenopausal uterine prolapse undrergo uterine prolapse surgery,the combined offering of progynova with vitamin E before operation can effectively improve the vaginal environment and regulate hormone level.It′s more in line with the operation condition,can reduce postoperative complication and improve the postoperative recovery effect,so that it′s worthy of clinical application and promotion.
2017 Vol. 24 (10): 115-118 [
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162
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Efficiency of oxytocin combined with carboprost tromethamine in treatment of postpartum hemorrhage in cesarean section with scarred uterus
WU Chun-yan
Objective To explore the efficiency of oxytocin combined with carboprost tromethamine in treatment of postpartum hemorrhage in cesarean section with scarred uterus.Methods 48 patiens with scarred uterus
received：
cesarean section in our hospital from March 2015 to February 2017,and were randomly divided into the control group and the treatment group,with 24 cases in each group.The control group was given oxytocin alone,while the treatment group was given oxytocin combined with carboprost tromethamine.The incidence of postpartum hemorrhage,the amount of postpartum bleeding at different tima,in both groups;postpartum bleeding at different times,duration of postpartum hemorrhage between two groups were compared.Results The incidence of postpartum hemorrhage in the treatment group(25.00%) was lower than that in the control group(50.00%);2,24 h after operation,the amount of postpartum bleeding in the treatment group[(223.51±31.48),(292.51±52.61)ml]were less than those in the control group[(294.39±52.77),(387.39±63.57)ml]; the duration of postpartum hemorrhage in the treatment group[(2.62±1.21)d]was shorter than that in the control group [(3.61±1.59)d],and all the differences were statistically significant(P＜0.05).Conclusion The effect of oxytocin combined with carboprost tromethamine on the prevention of postpartum hemorrhage is effective in reducing the incidence of postpartum hemorrhage,reducing the amount of postpartum hemorrhage and shortening the duration of bleeding.It is worthy to be popularized.
2017 Vol. 24 (10): 119-121 [
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129
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Clinical effect of childbirth without pain on primipara and on maternal and neonatal outcomes
QU Shu-ming
Objective To explore the clinical effects of childbirth without pain on primipara and on maternal and neonatal outcomes.Methods 200 cases of primipara in our hospital from October 2014 to August 2015 were selected and randomly divided into control group and observation group.The control group was
received：
conventional delivery methods,while the observation was received epidural anesthesia painless childbirth.The analgesic effect,birth process time,delivery way, maternal and child outcomes and analgesia satisfaction between two groups were compared.Results The exceuent and good rate for maternal analgesic of the observation group was significantly higher than that of the comtrol group,and the difference was statistically significant(100%vs.13.0%,P＜0.05);the observation group for first stage of labor,total labor were significantly shorter than those of the control group(P＜0.05);the observation group cesarean section rate(10.0%)was significantly lower than the control group(26.0%),the difference was statistically significant(P＜0.05);postpartum hemorrhage,1,5 min Apgar scores tetween two groups had no statistically significant(P＞0.05);analgesia satisfaction in the observation group was significantly higher than that in the control group,and the difference was statistically significant (99.0%vs.34.0%,P＜0.05).Conclusion The clinical painless childbirth for early maternity,can shorten the duration of labor,ease of early maternal pain,worthy of clinical use.
2017 Vol. 24 (10): 122-124 [
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121
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Case analysis of treatment of two patients with severe cutaneous allodynia with pregabalin
CHEN Jiang-ying；DENG Wan-qing；ZHANG Su-ping；YAN Zhen-wen
Cutaneous allodynia refers to pain sensation responding to innocuous stimuli delivered to skin.Two patients diagnosed severe cutaneous allodynia were given pregabalin 75-150 mg every time，twice a day for three weeks．Record the headache degree and sleep quality and the adverse drug reaction with visual analogue score(VAS)and sleep interfer ence score(SIS)before and after treatment.After treatment with pregabalin,the severity of headache and sleep quality were significantly improved,no side effect was observed.Pregabalin may improve the severity of headache and the quality of sleep of patients with severe cutaneous allodynia．
2017 Vol. 24 (10): 125-127转142 [
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149
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Efficiency of ulinastatin combined high-dose ambroxol on patients with severe pneumonia
YE Dong-ying；SHI Bin；YE Ming-rong；JI Zhen-xing
Objective To explore efficiency of ulinastatin combined high-dose ambroxol on patients with severe pneumonia.Methods Clinical datas of patients in our hospital diagnosed with severe pneumonia from 2013-2016 were selected, from which a random sample of 80 cases were selected and divided into the control group and the observation group according to the intervention methods,with 40 cases in each group.Patients in the control group were
received：
the general treatment for severe pneumonia,while patients in the observation group were received ulinastatin combined high-dose ambroxol on the basis of the control group.The chilical effect,the level of blood gas index and the walking distance of patients between two groups were compared.Results The effective rate of patients in the observation group(95.0%)was higher than that in the control group(82.5%).After treatment,the levels of blood oxygen pressure and oxygenation index of patients in the observation group[(61.2±10.3),(296.3±23.1)mmHg]were higher than those in the control group[(56.2±10.3), (159.1±25.7)mmHg];6 minutes walking distance in of patients in the observation group[(2.89.1±20.21)m]were longer than that in the control group[(256.9±19.8)m].All the differences were statistically significant(P＜0.05).Conclusion The prognosis of severe pneumonia patients with severe pneumonia poor quality,intervention plans for such patients in addition to consider to improve the condition,also should be to focus on the indicators and the quality of rehabilitation,ulinastatin combined high-dose ammonia bromine,the disease can not only control the condition and blood gas index and 6 minutes walking distance is relatively more obvious increase,also has comprehensive advantages,is worth promoting.
2017 Vol. 24 (10): 128-130 [
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Clinical effect observation of Entecavir combined with Diammonium Glycyrrhizinate Capsules in the treatment of chronic hepatitis B virus
MAO Jin-chao
Objective To observe the clinical effect of Entecavir combined with Ciammonium Glycyrrhizinate Capsules in the treatment of chronic hepatitis B.Methods 46 patients with chronic hepatitis B virus who were treated in the First People′s Hospital of Wenling from August 2014 to February 2016 were selected and randomly divided into the observation group and the control group,with 23 cases in each group.The control group was treated with Entecavir alone wihle the observation group was given Entecavir combined with Diammonium Glycyrrhizinate Capsule,the period of treatment were 6 months.The the recovery rates of ALT and AST,the negative conversion rates of HBV-DNA and HBeAg were compared between two groups.Results After 6 months treatment,The the recovery rates of ALT（82.6%）and AST（86.9%）in the observation group were higher than those in the control group（60.9%，56.5%）,and the differences were statistically significant(P＜0.05).The negative conversion rates of HBV-DNA（78.3%）and HBeAg（86.9%）in the observation group were higher than those in the control group,(69.6%,82.6%)but the differences were not statistically significant(P＞0.05).Conclusion Entecavir combined with Diammonium Glycyrrhizinate Capsules is better than Entecavir alone in the treatment of chronic hepatitis B virus.
2017 Vol. 24 (10): 131-133 [
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Professor HU Shi-ping′s clinical experience in the treatment of insomnia
ZHANG Yun-cheng；HU Shi-ping
Insomnia is the most common clinical disorder in the outpatient department of Traditional Chinese Medicine (TCM).Patients′clinical manifestations included difficulty in falling asleep,easiness to wake up and early wake-up.With the accelerated pace of life,people's life pressure is increasing,the incidence of insomnia is also showing a rising trend. Therefore,to seek effective treatment of insomnia has important clinical significance for improving people′s normal life quality.Professor HU Shi-ping has his own unique insights in common disorders such as dizziness,spleen and stomach disease,fatty liver,insomnia and somnolence etc..Professor HU Shi-ping prescribes medication in the treatment of insomnia according to syndrome differentiation.At the same time,he is expert in use of dampness dispelling and nerves soothing medication,which is the criterion for treatment of insomnia disease.
2017 Vol. 24 (10): 134-136 [
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Clinical effect research of oral Chinese medicine combined with enema treating uterine fibroids of phlegm and blood stasis mutual junction
JIANG Li-hua；ZHENG Ying-mei；ZHAO Sui-qin；XIE Yi-jin
Objective To investigate clinical effect of oral Chinese medicine combined enema treating uterine fibroids of phlegm and blood stasis mutual junction.Methods 72 patients with uterine fibroids of phlegm and blood stasis mutual junction treated by outpatient of Gynecology and Obstetrics Department in our hospital from May 2014 to May 2015 were screened,and they were randomly divided into control group and treatment group,and there were 36 cases in each group.The control group was given oral Guizhi Fuling Capsules,while the treatment group was given homemade Chinese medicine removing blood,reducing phlegm and stasis combined with enema prescription of Chinese medicine for enema. Two groups of patients were continuously for 15 days after the menstrual period,and treatment lasted for three menstrual cycles.Uterine volume,fibroid volume,blood estradiol(E2),progesterone and total efficient rate before and after the treatment in two groups were observed.Results The total effective rate in the treatment group(66.7%)was significantly higher than that of the control group(27.8%),and the difference was statistically significant(P＜0.05).There was no significant alteration of the two groups before and after treatment in patients with uterine volume,and there was no statistical difference within the group and between groups(P＞0.05).After treatment,fibroid volume was reduced in the treatment group compared with before treatment,and there was a statistical difference(P＜0.05),while there was no significant change in the control group(P＞0.05),the difference between the two groups after treatment was statistically significant (P＜0.05).After treatment,the level of E2was significantly lower than the control group,the difference was statistically significant(P＜0.05).There was no significant change in the two groups before and after treatment and the treatment for progesterone level,there was no significant difference between the two groups after treatment(P＞0.05).Compared with before treatment,the level of E2was significantly lower after treatment in treatment group,and the difference was statistically significant(P＜0.05).Conclusion The effect of oral Chinese medicine combined with enema treating uterine fibroids of phlegm and blood stasis mutual junction is significant,and it is worthy of clinical promotion and application.
2017 Vol. 24 (10): 137-139转152 [
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144
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ClinicaleffectofCombinationofNerves-SoothingDecoctionand acupuncture in treatment of cardiovascular neurosis
LU Hai-yan；CHEN Zhi-biao
Objective To investigate the clinical effect of combination of Nerves-Soothing Decoction and acupuncture in the treatment of cardiovascular neurosis.Methods Altogether 210 patients with cardiovascular neurosis who were treated in department of Traditional Chinese Medicine(TCM)Internal Medicine in our hospital from July 2011 to May 2015 were divided into two groups.Control group was treated with Nerves-Soothing Decoction,while observation group was treated with combination of nerves-soothing decoction and acupuncture;the curative effect,TCM symptom improvement, Hamilton Anxiety and Depression Scale(HAMD)and self-rating symptom scale(SSS)score between two groups were compared.Results The total effective rate of treatment of observation group(97.14%)was significantly higher than that of control group(75.24%),with statistically significant difference(P＜0.05).The post-treatment TCM symptom score of observation group in palpitation and shortness of breath,dizziness,head and body heaviness,insomnia and sweating fatigue were significantly lower than those of control group,with statistically significant difference(P＜0.05).The posttreatment HAMD and SSS score of observation group were significantly lower than those of control group,with statistically significant difference(P＜0.05).Conclusion Combination of Nerves-Soothing Decoction and acupuncture in the treatment of cardiovascular neurosis achieves good clinical effect and can relieve the symptoms,which can improve patients′physical and mental health and is of great clinical significance.
2017 Vol. 24 (10): 140-142 [
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159
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Clinical effect of Xingnao Kaiqiao Acupuncture combined with Buyang Huanwu Decoction treating apoplectic sequela
LYU Jian-xing；HUANG Hai-heng
Objective To explore the clinical effect of Xingnao Kaiqiao Acupuncture combined with Buyang Huanwu Decoction treating apoplectic sequela,and to provide the basis for clinical application.Methods One hundred and twenty patients with apoplectic sequela admitted inyo our hospital from January 2014 to January 2016 were selected as object.According to the different treatment methods,the patients in the control group(n=100)were given acupuncture and conventional therapy,while the observation group(n=100)was treated with Buyang Huanwu Decoction on the basis of acupuncture,the two groups of patients were evaluated after 2 months of treatment.Results The score of physical function,body pain and social function were significantly higher in the observation group than in the control group(P＜0.05). The general health status,vitality,social function,emotion(P＞0.05).In the observation group,the total effective rate of the observation group(96.0%)was obviously higher than that of the control group(67.0%),and the difference was statistically significant(P＜0.01).Indicating that the addition of Buyang Huanwu Decoction can effectively improve the clinical efficacy of patients.Conclusion Xingnao Kaiqiao Acupunture combined with Buyang Huanwu Decoction in the treatment of apoplectic sequela obtains an significant clinical effect,and it is worthy of promotion the application.
2017 Vol. 24 (10): 143-145 [
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162
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Investigation and analysis on the application status of cryoprecipitated antihemophilic factor in Zhaoqing Area
LU Shao-fen；PI Yan；CHEN Fu-ru；HE Yu-bing；LUO Huai-xue
Objective To investigate the application status of cryoprecipitated antihemophilic factor in the past four years in Zhaoqing Area,to analyse existing problems and to provide an effective reference for the formulation of blood components inventory plan and guideline for the use of clinical blood products.Methods The clinical blood volume and preparation volume in Zhaoqing Area from January 2013 to December 2016 were analyzed statistically.Results From January 2013 to December 2016,the use of cryoprecipitated antihemophilic factor in Zhaoqing Area increased from 34 974 U to 50 489 U,and the satisfaction rate decreased from 107%to 98%.The fresh frozen plasma prepared in 13 hours after collection was used as raw material slurry for preparing cryoprecipitated antihemophilic factor starch.The total amount of fresh frozen plasma prepared by cryoprecipitated antihemophilic factor in Zhaoqing Area increased by 3 270 200 ml,the increase from 24%to 36%,which improved the preparation of cryoprecipitated antihemophilic factor.Conclusion With the improvement of medical level and the implementation of the composition of blood transfusion,the use of cryoprecipitated antihemophilic factor in Zhaoqing Area will continue to increase.Therefore,the blood bank should be to ensure blood quality and quality of service,while the cryoprecipitated antihemophilic factor should be carried out indepth investigation of the use of clinical scientific and rational use of blood products to provide guidance,so as to ensure that blood products can be rational and effective use,and reduce the risk.
2017 Vol. 24 (10): 146-148 [
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166
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Analysis on epidemic characteristics of 443 death cases of road traffic injury in a hospital in Doumen District of Zhuhai City
ZHANG Huang-hui；LIU Hong-wei
Objective To explore epidemic characteristics of death cases of road traffic injury(RTI)in a hospital and to provide the evidence of RTI control and prevention.Methods 443 cases information with RTI were collected in a hospital from January 2008 to December 2015.The main indicators of observation included patient basic information(name, gender,age,occupation,cultural degree,etc.),damage diagnosis information,hospitalization information,death information, etc..The statistical analysis of death cause was carried out according to the international classification of diseases ICD-10.Results From 2008 to 2015,the inpatients of RTI in a hospital of Zhuhai were 10 974 cases,of which RTI death were 443 cases.The average fatality rate of RTI was 4.0%with no significant change in the annual fatality rate trend(P＞0.05).The fatality rate of RTI of Males was 4.4%,which was higher than that of females(3.1%)(OR=1.449,P＜0.01).RTI was the first cause in any of the injure causes of death,its constituent ratio as high as 63.5%with no significant change in the annual constituent ratio trend(P＞0.05).Motorcycle was the first traffic injury reason,accounting for 55.0%.Male motorcycle injury death ratio(88.1%)was significantly higher than that of women(11.9%)(P＜0.01).Group of motorcycle injury death in young adults(76.4%)was significantly higher than other age groups(P＜0.01).Conclusion Road traffic injuries in male youths and motorcyclist are high-risk groups,which should take timely and effective prevention and control measuresaccording to the types and distribution characteristics of RTI to reduce the incidence of road traffic injury and case fatality rate.
2017 Vol. 24 (10): 149-152 [
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Investigation and study of public basic first-aid knowledge and skill mastery for family service employees
GONG Huan-qiu；WU Yu-huan；ZHANG Gui-fen；HE Min-ying；LIANG Qi-ying；ZHU Liu-yi；XIAO Pei-yi；DENG Xia；LI Chong-hong
Objective To investigate comprehensively the public basic first-aid knowledge and skill mastery for family service employees of Foshan City,and evaluate the ability of self rescue and rescue in the accidents happened in daily life,and to provide scientific reference for the different forms of training conducted in the family,community and intermediary.Methods 140 family service employees extracted from family service agencies,intermediary and community in the local area from August 2014 to December 2015 were selected as the research object,there are 4 different levels of the crowd of 140 people including the elderly and patient care,infant care,household cleaning and home cooking.Face to face questionnaire survey was used and college intern in Chencun Hospital Affiliated to the First People′s Hospital of Shunde District in Foshan City were selected as a researcher.The level of knowledge,knowledge of health and food safety knowledge and the ability to respond to emergencies were analyzed using SPSS 20 statistical software.Results In the event of an emergency,there was no statistical difference of in the right for master degree,mastery of knowledge of firstaid knowledge,understanding of basic CPR degree,first-aid knowledge and skills needing degreee and be willing to accept the professional training of first aid skills degree in 4 different levels of people(P＞0.05).There was a statistical difference of mastering the usage degree of simple first-aid tools(P＜0.05),and there was no statistical difference of the grasp of CPR operation for 4 different level groups(P＞0.05).Conclusion The mastery level of public basic first-aid knowledge and skill in family service employees of Foshan City is lower,so it is necessary to strengthen the public awareness of and popularize the related knowledge of first-aid.
2017 Vol. 24 (10): 153-155 [
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Study of stigma on family members of schizophrenic patients with compulsory medical treatment and related factors
HUANG Shi-wei；LIU Zheng-rong；ZHANG Hai-xiang；WANG Yun-fang；XU Qu；ZHENG Wei
Objective To explore the incidence rate of stigma on family members of schizophrenic patients with compulsory medical treatment and its related factors.Methods From March to November 2016,a total of 208 family members of schizophrenic patients meeting the diagnostic standard of International Classification of Diseases(ICD-10)in our hospital were selected.The demographic general information including age,gender,education level(calculated by year), personal income(3000 yuan for the cut-off),place of residence,etc.,stigma,quality of life,suicidal attempt,and insomnia were evaluated by home-made questionnaire,belittlement-discrimination scale,and World Health Organization Quality of Life Scale.Results The data were collected in 198 cases,and the response rate was 98.2%.62.1%family members of schizophrenic patients had a sense of disgrace.Compared with stigma group,participants in the non-stigma group more lived in urban areas(χ2=10.377,P=0.001),with a higher quality of life(t=18.883,P=0.023),which were displayed statistical differences. In comparison with the non-stigma group,family members in the stigma group with higher education levels(t=7.101,P= 0.0001)and higher income(χ2=13.067,P=0.0001),as well as more occurrence of insomnia(χ2=15.647,P=0.0001)and suicidal attempt(χ2=4.548,P=0.033),which were displayed statistical differences.There were positive correlations between educational level,monthly income,insomnia and suicide attempts in family members and stigma.Conclusion The stigma is existent in over half family members with schizophrenic patients.In addition,family members with high levels of education,high-income,insomnia and suicide attempts are more likely to feel disgraceful.
2017 Vol. 24 (10): 156-158 [
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159
Application and observation of modified washing head in bed in liver cancer patients lying in bed treated with TACE
ZHOU Bi-yun；CHEN Yin-qin；PENG Bi-wen；CHEN Qiao-ya；TANG Cai-ming
Objective To explore the application effect of modified washing head in bed in liver cancer patients lying in bed treated with transhepatic arterial chemotherapy and embolization(TACE).Methods A total of 80 liver cancer patients lying in bed treated with TACE from January to December 2016 in our hospital were selected and evenly divided into observation group and control group in random,40 cases in each group.In the control group,traditional simplified washing head in bed was used,while in the observation group,the modified one was applied.The effect of washing head and patient′s satisfaction were compared.Results In the observation group,washing time was(15.12±2.41)min and wetting area of bed sheet was(6.51±1.23)cm×cm,greatly better than those in the control group of(20.43±1.32)min and(30.15±3.56) cm×cm respectively.The total nursing satisfaction by patients in the observation group was 95.0%,much higher than that in the control group accounting for 82.5%with a statistical difference(P＜0.05).Conclusion Modified washing head in bed not only saves nursing staff′s time,also improves patient′s satisfaction,which is worthy of application and promotion in clinic.
2017 Vol. 24 (10): 159-161 [
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155
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Application of comfortable nursing in patients with cesarean section
HUANG Zhi-jun；PAN Yan-ying；HE Xiang-hong；CHEN Jin-yan；HUANG Shui-feng
Objective To explore the comfortable nursing on the physiological and psychological influences in women with cesarean section during childbirth.Methods From June 2014 to June 2016,160 primiparae performed with cesarean section in our hospital were selected as research objects and evenly divided into observation group and control group in random.In the observation group,regular nursing plus comfortable nursing was adopted,while in the control group,only regular nursing was used.The anxiety,postoperative recovery,postoperative pain,and nursing satisfaction were evaluated. Results There was no significant difference in SAS scores between the two groups before treatment(P＞0.05).After invervention,the SAS score in the control group was higher than that in the observation group(P＜0.05).In the observation group, time to be off bed after surgery,first anal exhaust time,and lactation yield in the third day after surgery were all superior to those in the control group with statistical differences(P＜0.05).The VAS score of postoperative pain was lower and score of nursing satisfaction was higher in the observation group,which were both displayed statistical differences(P＜0.05). Conclusion Comfortable nursing canreduce maternal anxiety,alleviate postoperative pain,promote quick postpartum recovery,and improve lactation as well as nursing satisfaction.
2017 Vol. 24 (10): 162-164转171 [
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120
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Clinical study of prognova combined with comprehensive nursing intervention model in patients with breast swelling after odinopoeia
LIU Xu-dong；HUANG Xiao-lan；LAI Quan-ying
Objective To explore the clinical effect of prognova combined with comprehensive nursing intervention model in patients with breast swelling after odinopoeia.Methods 87 patients with breast swelling after odinopoeia from December 2015 to December 2016 of our hospital were selected as study objects.Patients were divided into observation group and control group by using random number table.There were 44 cases in the observation group and 43 cases in control group.The observation group were treated with prognova combined with comprehensive nursing intervention,and the control group were treated with prognova and general nursing after induction of labor.The clinical effect of two groups were compared.Results 4,7 days after odinopoeia,the VAS score and breast hardness in observation group were obvious lower than those in control group,the difference was statistically significant(P＜0.05).Conclusion Prognova combined with comprehensive nursing intervention model in patients with breast swelling after induction of labor can effectively alleviate the pain of patients,decrease breast hardness,with obvious effect and its worthy of popularizeation and application.
2017 Vol. 24 (10): 165-167 [
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149
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Effect of comprehensive nursing intervention on self-management ability and psychological state of patients with coronary heart disease
MA Li；LI Chun-hong；WU Hai-tao
Objective To explore the effect of comprehensive nursing intervention on self-management ability and psychological state of patients with coronary heart disease(CHD).Methods Altogether 520 cases of CHD patients who were treated in our center and Integrated Traditional Chinese and Western Medicine Hospital of Fengtai District from January 2015 to May 2016 were selected as the object of this research and randomly divided into observation group(n= 260)and control group(n=260).The control group was treated with routine nursing,while,the observation group was given comprehensive nursing care based on theroutine nursing.The self-designed self-management ability questionnaire, self-rating anxiety scale(SAS)and self rating depression scale(SDS)of CHD patients were used.The pre-interventional and 3-month post-interventionalself-management ability and mental state of the two groups were compared.Results The pre-interventional SDS and SAS scores of observation group and control group were(61.22±5.12)points vs.(60.88± 4.52)points and(56.46±6.13)points vs.(56.35±5.42)points,without significant difference between the two groups(P＞0.05).The post-interventional SDS and SAS scores of observation group and control group were(40.33±6.45)points vs. (51.62±4.90)points and(42.11±5.25)points vs.(49.61± 4.71)points,significantly decreased compared with preintervention ones(P＜0.05).In addition,the post-interventional self-management ability of patients in observationgroup was significantly better than that of control group in the five aspects,including self-regulation(85%vs.51.92%), proper exercise(90.38%vs.65.00%),diet control(93.08%vs.60%),medication management(93.08%vs.53.85%)and periodic review(96.15%vs.43.08%)(P＜0.05).Conclusion Comprehensive nursing intervention can effectively promote the self-management ability of patients with CHD,improve the psychological status and the quality of life of CHD patients,which plays an important role in the increase of the CHD patients′confidence to overcome the disease and the courage to face life.
2017 Vol. 24 (10): 168-171 [
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Influence of posture nursing on intracranial pressure,mean arterial pressure and cerebral perfusion pressure in patients with critical conditions undergone craniotomy
SUN Jie；LIU Bing-lan；LEI Yuan-hua
Objective To explore the influence of posture nursing on intracranial pressure(ICP),mean arterial pressure (MAP)and cerebral perfusion pressure(CPP)in patients with severe conditions undergone craniotomy.Methods A total of 40 patients with severe craniocerebral injury who were provided with craniotomy from March 2015 to February 2016 were selected.All patients were nursed in 0°,10°,20°,30°and 40°postures.The ICP,MAP and CPP were compared in different positions,and the correlation analysis was performed.Results The level of ICP was gradually decreased ranging from 0°to 40°with statistical differences(P＜0.05).The MAP level was also decreased gradually at 0°to 40°,which was displayed statistical differences(P＜0.05).The levels of CPP was(69.7±5.5),(70.2±4.4),(71.1±3.9),(74.5±3.6)mmHg were gradually increased at 0°to 30°.At 40°,the level of CPP was（63.5±3.5）mmHg,significantly lower than those at 0°to 30°with statistical differences(t=6.015,P=0.000;t=7.537,P=0.000;t=9.173,P=0.000;t=13.856,P=0.000).By correlation analysis,posture was in great negative correlation with ICP and MAP in patients with critical conditions after craniotomy (r=0.732,P=0.000;r=0.757,P=0.000).Conclusion Posture nursing has a certain influence on the levels of ICP,MAP,and CPP in patients with critical conditions undergone craniotomy.Among them,posture at 30°to 40°,the levels of ICP and MAP are both decreased,and CPP is in rise simultaneously,which is beneficial to patient′s prognosis.
2017 Vol. 24 (10): 172-174 [
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Effect of comprehensive nursing on lung injury caused by Paraquat poisoning
YANG Qiu-na
Objective To investigate the effect of comprehensive nursing on lung injury caused by Paraquat poisoning. Methods The clinical data of 59 patients with lung injury caused by Paraquat poisoning who were treated in our hospital from January 2013 to December 2015 were analyzed.The patients were divided into control group(n=29)and comprehensive nursing group(n=30)according to the different nursing measures.The pre-and post-nursing lung injury score and the prognosis of two groups were observed.Results The pre-nursing imaging examination,respiratory system compliance changes,positive end expiratory pressure changes and hypoxemia scores of two groups were(6.8±2.0)points vs. (6.9±2.1)points,(7.2±2.1)points vs.(7.4±2.0)points,(7.3±2.3)points vs.(7.5±2.4)points and(7.4±2.2)points vs.(7.5±2.1) points,with no significant difference(P＞0.05).The post-nursing imaging examination,respiratory system compliance changes,positive end expiratory pressure changes and hypoxemia scores of two groups were(4.9±1.5)points vs.(3.4± 1.2)points,(5.0±1.3)points vs.(3.3±1.2)points,(5.1±1.4)points vs.(3.2±1.0)points and(4.8±1.3)points vs.(3.0±1.1) points,lower than those before nursing,the post-nursing imaging examination,respiratory system compliance changes, positive end expiratory pressure changes and hypoxemia scores of comprehensive nursing group were lower than those of control group.The hospitalization time,gastrointestinal bleeding,kidney damage,infection and mortality rate of comprehensive nursing group were(8.2±1.8)d,10.0%,3.3%,0 and 10.0%,which were lower than those of control group′s (12.8±2.0)d,41.4%,17.2%,17.2%and 41.4%,with statistically significant difference(P＜0.05).Conclusion Application of comprehensive nursing in patients with lung injury caused by paraquat poisoning can improve the patients′prognosis and reduce the degree of lung injury,which is worthy of clinical application.
2017 Vol. 24 (10): 175-177转181 [
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Application of PDCA cycle theory in the management of pediatric peripheral venous infusion with indwelling needle
LIU Li；CAI Shan-shan；PENG Fei-yan
Objective To explore the application effect of PDCA cycle theory in the management of pediatric peripheral venous infusion with indwelling needle.Methods A total of 180 children undergoing treatment of peripheral venous indwelling needle from January 2014 to December 2015 were selected as research objects.90 cases before application of PDCA cycle theory from January to December 2014 were taken as control group,while 90 cases after application of PDCA cycle theory from January to December 2015 were taken as observation group.Children in control group were given routine nursing care,while children in observation group were given nursing management based PDCA cycle theory.The retention time,unplanned extubation rate,catheter-related complications and nursing satisfaction were compared between the two groups.Results The retention time of indwelling needle in observation group was(92.78±3.45)h longer than that in control group of(87.96±4.62)h;the unplanned extubation rate and catheter-related complications rate in observation group were 3.3%and 6.6%respectivly both lower than those in control group(18.9%and 22.2%);the nursing satisfaction in observation group was 97.8%higher than that in control group of 86.7%,the difference was statistically significant(P＜0.05).Conclusion The application of PDCA cycle theory in pediatric peripheral indwelling needle can extend the retention time,reduce unplanned extubation rate and catheter-related complication rate,and improve nursing satisfaction.
2017 Vol. 24 (10): 178-181 [
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Application of humanized nursing in the treatment of pediatric pneumonia by oxygen-driven atomized inhalation of budesonide
ZENG Wei
Objective To study the application effect of humanized nursing in the treatment of children with pneumonia by oxygen-driven atomized inhalation of budesonide.Methods The research objects of 83 cases with pediatric pneumonia were randomly selected from January 2014 to November 2015 in our hospital.By a random number table,they were divided into group A(n=41)and group B(n=42).All participants were treated by oxygen-driven atomized inhalation of Budesonide.In the group A,conventional nursing measure was used,while in the group B,humanized nursing was adopted.The treatment compliance of aerosol inhalation,degree of mastering knowledge about aerosol inhalation by patient′s parents and degree of proficiency of performing aerosol inhalation,clinical symptoms score and score of quality of life before and after intervention,persisting time of fever,cough,and expectoration,and hospital stay were compared in the two groups.Results The treatment compliance of aerosol inhalation for pneumonia in the group B was higher than that in the group A(P＜0.01).Degree of mastering knowledge about aerosol inhalation by patient′s parents and degree of proficiency of performing aerosol inhalation in the group B was better than those in the group A(P＜0.01).Before intervention,the clinical symptoms score and quality of life score in the two groups were similar(P＞0.05).After intervention,they were improvement in the group B than group A(P＜0.05).The persisting time of fever,cough,expectoration as well as hospital stay in the group B were all shorter than those in the group A(P＜0.01).Conclusion Oxygen-driven aerosol inhalation of budesonide in the treatment of pneumonia in children is effective.Assisted by humanized nursing as intervention measure,it can strengthen the understanding of aerosol inhalation in children′s parents in right performance as well as increase the treatment compliance by pediatric patients,which obtain definite effects on promoting clinical symptoms resolving and improving the quality of life,and it is worthy of promotion.
2017 Vol. 24 (10): 182-184 [
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Nursing effect of different nursing care modes in children with high fever
HE Ting-xi
Objective To study the effect of the routine nursing care and the specific nursing care in children with high fever respectively.Methods 100 children patients with high fever from January 2016 to January 2017 were selected and divided randomly as the intervention group and the control group,50 cases in each group.Patients in both groups were given the routine nursing care.On the basis of the routine nursing care,the specific nursing care was given to patients in the intervention group.Nursing effect of the two groups was compared.Results Temperature of children patients in intervention group was（37.5±0.2）℃,lower than（38.3±0.2）℃of the control group after the nursing care（P＜0.05）.The total clinical effective rate of children patients in the intervention group was 96.0%,higher than 80.0%of the control group（P＜0.05）.The nursing care total satisfaction degree of children patients in the intervention group was 98.0%, higher than 84.0%of the control group（P＜0.05）.The incidence rate of complication of children patients in the intervention group was 6.0%,lower than 20.0%of the control group（P＜0.05）.Conclusion On the basis of the routine nursing care,the clinical application of specific nursing care to children patients with high fever promotes the rehabilitation significantly.Additionally,it also improves the degree of satisfaction of parents of children patients, decreases the incidence rate of complication,which is worth clinical promotion and application.
2017 Vol. 24 (10): 185-187 [
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Analysis of the effect of nursing management of patients with ostomy wound code
LIU Chun-mei；CHEN Ying-fang；CHEN Ting
Objective To investigate the effect of standardized nursing management on patients with wound stoma. Methods 96 cases of patients with wound stoma in our hospital from July 2015 to July 2016 were randomly divided into observation group and control group,each with a total of 48 cases.The control group was treated with conventional ostomy wound nursing,the observation group in the control group on the basis of the implementation of standardized management of nursing records,two groups of patients after nursing and scored ostomy wound incidence and nursing satisfaction were compared between the two groups.Results the observation group wound score[(94.87±0.75)points],stoma[(95.47±0.51)points]score and incontinence score[(97.25±1.01)points]was significantly higher than the control group [(45.38±1.68),(37.62±1.25)points]and[(48.66±1.52)points],the difference was statistically significant(P＜0.05);observation group high incidence of pressure ulcers(0%)and the total incidence rate(6.25%)was lower than that of the control group(8.33%)and(22.92%),the difference was statistically significant(P＜0.05).The clinical nursing satisfaction of the observation group was 95.83%(n=46),and the control group was 72.92%(n=35).The difference was statistically significant(P＜0.05).Conclusion The implementation of standardized nursing management can significantly improve patients'wound wound score in wound care of colostomy patients,reduce the incidence of pressure ulcer patients,application effect,promote the positive significance to improve the clinical nursing satisfaction,is worthy of clinical use.
2017 Vol. 24 (10): 188-190 [
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129
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Effect of nursing intervention on postpartum outcome in patients with pregnancy induced hypertension
LU Jing-ming
Objective To study the effect of nursing intervention on postpartum outcomes in patients with pregnancy induced hypertension(PIH).Methods Altogether 136 cases of PIH pregnant women who were treated in our hospital from December 2013 to January 2016 were divided into control group and study group according to the random number table method,68 cases in each group.The control group was given general nursing service;while,the study group was given early nursing intervention.The postpartum outcome,fetal outcome,clinical nursing service satisfaction as well as preand post-interventional maternal blood pressure of two groups were summarized and compared.Results The postpartum hemorrhage,cesarean section rate of control group were higher than those of study group(P＜0.05);however,there was no significant difference in incidence of placental abruption and preeclampsia(P＞0.05).The incidence of asphyxia,fetal distress,premature delivery of control group was higher than that of study group(P＜0.05).The total satisfaction of clinical nursing service was 80.88%in control group,lower than that of 97.06%in study group(P＜0.05).The maternal blood pressure of two groups were measured at admission,but the results were not statistically significant(P＞0.05),the post-interventional maternal diastolic blood pressure and systolic blood pressure of study group were lower than those of control group(P＜0.05).Conclusion Application of perinatal nursing interventions for maternal pregnancy induced hypertension have lower incidence of postpartum hemorrhage,placental abruption,preeclampsia and cesarean section as well as asphyxia,fetal distress and premature birth.Most of puerperasare satisfied with the nursing serviceand have a better control of blood pressure after nursing intervention.
2017 Vol. 24 (10): 191-193 [
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Influence of comfort care on quality of life and comfort in elderly patients with chronic obstructive pulmonary emphysema
HONG Mei
Objective To evaluate the influence of comfort care on quality of life(QOL)and degrees of comfort in elderly patients with chronic obstructive emphysema(COE).Methods The clinical data of 156 elderly patients with COE admitted in Zhangzhou People′s Hospital from March 2014 to April 2016 were analyzed.According to the different nursing measures,they were divided into control group(n=56)and comfort care group(n=100).In the control group,common care measures were used,while in the comfort care group,comfortable nursing measures were adopted.The QOL scores and comfort assessment before and after nursing in both groups were observed.Results There were no significant differences in body function,role function,emotional function,cognitive function,social function and overall QOL scores before nursing in two groups(P＞0.05).After nursing,these indexes were higher than before nursing,the indexes in the comfort care group were all higher than those in the control group after nursing.The comfort was 98.0%in the comfort care group higher than that in the control group accounting for 60.7%,which were all displayed statistical differences(P＜0.05). Conclusion The application of comfort care in elderly patients with COE can improve the QOL and comfortable degrees,which is worthy of clinical promotion.
2017 Vol. 24 (10): 194-196 [
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