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| Effect of estradiol valerate combined with vitamin E on the vaginal wall of postmenopausal uterine prolapse surgery |
| GAO Hai-yan |
| Department of Obstetrics and Gynecology,Maternal and Child Health Hospital of Guangning County in Guangdong Province,Zhaoqing526300,China |
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Abstract Objective To investigate the effect of estradiol valerate combined with vitamin E on vaginal wall of postmenopausal uterine prolapse surgery.Methods 60 patients with postmenopausal uterine prolapse admitted to our hospital from March 2014 to September 2016 were selected as study object.They were randomly divided into two groups with a total of 30 cases in each group by random number table method.Among them,30 patients underwent direct uterine prolapse surgery(vaginal hysterectomy＋vaginal wall repair surgery)for treatment were served as control group,and the other 30 patients underwent preoperative estradiol valerate combined with vitamin E and uterine prolapse surgery for treatment were served as the observation group.Endovaginal condition,treatment condition,complication and quality of life,etc.of patients in two groups were observed.Results The level difference for MI,KI,VHS,vaginal mucosal thickness, FSH and E2for patients in two groups before treatment were compared with no difference(P＞0.05),the difference was statistically significant between two groups after treatment(P＜0.05).There was no statistical difference in control group before and after treatment besides VHS(P＞0.05);there were significant differences in observation group before and after treatment for all indexes(P＜0.05).There was no significant difference between the two groups for endometrial thickness (P＞0.05).After 1 week of the operation,there was no significant difference in the life quality for patients in two groups (P＞0.05).After 1,3 months of the operation,the life quality score of observation group was significantly higher than that of control group and the difference was statistically significant(P＜0.05).Conclusion When patients with postmenopausal uterine prolapse undrergo uterine prolapse surgery,the combined offering of progynova with vitamin E before operation can effectively improve the vaginal environment and regulate hormone level.It′s more in line with the operation condition,can reduce postoperative complication and improve the postoperative recovery effect,so that it′s worthy of clinical application and promotion.
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