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2020 Vol. 27, No. 21
Published: 2020-07-28
 
 
4 Diagnostic value of combined detection of serum tumor markers for gastric cancer
SUN Hui; ZHU Li-jing; WANG Zheng-qian
Objective To evaluate the diagnostic value of several serum tumor markers in patients with gastric cancer by using receiver operating characteristic (ROC) curve. Methods A total of 57 patients with gastric cancer (group A),50 patients with benign gastric lesions (group B) and 50 healthy patients with normal gastric mucosa (group C) from January 2016 to December 2017 in our hospital were selected as the research objects.Expression levels of carcino embryonic antigen (CEA),carbohydrate antigen 72-4 (CA72-4),carbohydrate antigen 50 (CA50),carbohydrate antigen 19-9 (CA19-9) and carbohydrate antigen 242 (CA242) in serum for the three groups were detected by electrochemiluminescence.ROC curve was carried for analysis. Results The expression levels of CEA,CA72-4,CA50,CA19-9 and CA242 in group A patients were higher than those in group B and group C,the differences were statistically significant(P<0.05).With the progress of gastric cancer staging,the positive detection rate of CEA,CA72-4,CA50,CA19-9 and CA242 in the serum of gastric cancer patients showed an increasing trend.When the tumor markers were detected individually,the AUC of CA19-9 was 0.777,and the sensitivity of CA72-4 was the highest,which was up to 77.7%.The diagnostic accuracy of combined detection of tumor markers was improved.The AUC of the combined detection of CA50,CA72-4,CA19-9 and CA242 was 0.925,and the sensitivity increased to 78.7%. Conclusion The combined detection of CA50,CA72-4,CA19-9 and CA242 can effectively improve the accuracy and sensitivity of diagnosis of gastric cancer patients,and has important clinical diagnosis and application value.
2020 Vol. 27 (21): 4-7 [Abstract] ( 32 ) HTML (35 KB)  PDF  (0 KB)  ( 6 )
8 Clinical effect of Zengye Chengqi Decoction combined with regular digital rectal stimulation in the treatment of the upper motor neurogenic constipation after spinal cord injury
HUANG Bao-yun；HE Zheng； YANG Xing-hua；XU Su-xiang1
Objective To investigate the effect of Zengye Chengqi Decoction combined with regular digital rectal stimulation (DRS) in the treatment of the upper motor neurogenic constipation after spinal cord injury (SCI).Methods A total of 48 patients with constipation post SCI admitted to Guangdong Work Injury Rehabilitation Hospital from January 2017 to December 2018 were selected as research subjects.They were divided into treatment group and control group by the random number table method,24 cases in each group.The control group was given the regular defecation management with DRS,while the treatment group was given oral Zengye Chengqi Decoction,and the regular DRS.The treatment course of two groups were all 3 weeks.The patients′ defecation frequency,defecation speed,Bristol stool character score before and after treatment and the adverse reactions were recorded and compared,and the clinical effect of the two groups were analyzed with statistics. Results After treatment,the defecation period and defecation time score of the patients in the treatment group were lower than those in the control group,and the normal proportion of fecal characteristics was higher than that in the control group,with statistically significant differences (P<0.05).In addition,the defecation period and defecation time of the two groups after treatment were shorter than those before treatment,and the normal proportion of defecation characteristics was higher than that before treatment,with statistically significant differences (P<0.05).Conclusion The treatment of the upper motor neurogenic constipation after SCI with Zengye Chengqi Decoction combined with regular DRS is effective,and the curative effect is better than that of the simple regular DRS.
2020 Vol. 27 (21): 8-11 [Abstract] ( 39 ) HTML (37 KB)  PDF  (0 KB)  ( 9 )
12 Effect of Nimodipine pretreatment on cognitive function in burned rats
LIU Tian-lin； QU Min
Objective To investigate the effect of Nimodipine on cognitive function in burned rats and its mechanism.Methods A total of 32 healthy male SD rats aged 18 months were selected.The rats were divided into four groups (n=24) by random number table method: control group (group C),surgery group (group S),Nimodipine group (group D),Nimodipine + surgery group (group D+S).Groups D and D+S were intraperitoneally injected with 1mg/kg Nimodipine,while groups C and S were given the same amount of normal saline;30 min later,the group S and group D+S were anesthetized and burned models were created.Group C was the blank control group.Morris water maze method was used to record the escape latency and crossing times of rats 1 day before operation and the 1st,3rd,7th days after operation.After completing,the Morris water maze,the rats were sacrificed and their hippocampus were collected.The tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in the hippocampus were detected by ELISA.MRNA expressions of hippocampal Bax and Bcl-2 were determined by RT-PCR.The apoptosis rate of hippocampal neurons was measured by flow cytometry. Results Compared with 1 day before the operation,there were no significant differences in the average escape latent period and crossing times between group C and group D on the 1st,3rd,and 7th days after operation(P＞0.05).Compared with group C，the average escape latent period of group S and D+S was prolonged and the crossing times were reduced on the 1st，3rd and 7th days after operation (P＞0.05).Compared with group S ,the average escape latent period of the group D+S at the same time was shortened and the crossing times at the same time were increased on the 1st，3rd and 7th days (P<0.05).Compared with group S,the levels of TNF-α and IL-6 in the hippocampus of the rats in the group D+S were decreased,the mRNA expression of Bax in hippocampal neurons was reduced,the mRNA expression of Bcl-2 was increased,the ratio of Bax/Bcl-2 was reduced,and the apoptosis rate was decreased (P<0.05).Conclusion Nimodipine can improve postoperative cognitive dysfunction in burned elderly rats by inhibiting inflammatory response and decreasing hippocampal neuron apoptosis.
2020 Vol. 27 (21): 12-15 转21 [Abstract] ( 37 ) HTML (46 KB)  PDF  (0 KB)  ( 8 )
16 Meta-analysis of the effect of intravenous injection of iron disaccharide in the treatment of postpartum iron deficiency anemia
QIU Wen-wen；WEI Li-li；LI Hai-hong； QIU Jie； LIAN Rui-han； HU Ya-guang；LIU Yu-yu；YANG Ke-hu
Objective To systematically evaluate the effectiveness and safety of intravenous injection of iron disaccharide and oral ferrous sulfate in patients with postpartum iron deficiency anemia. Methods PubMed,Cochrane Library,Web of Science,EMbase,CBM,WanFang Data,CNKI,VIP database were searched by the computer.At the same time,the relevant references were traced,and the randomized controlled trials (RCTs) of the effect of the intravenous injection of iron disaccharide (iron sucrose,iron carboxymaltose) in the experimental group and the oral ferrous sulfate in the control group on hemoglobin and ferritin after postpartum iron deficiency anemia were collected.The retrieval period was from database construction to June 2019.According to the inclusion criteria and exclusion criteria,two researchers independently screened the literature,extracted the data and evaluated the risk of bias in the included study.Then,RevMan 5.3 software was used for Meta-analysis. Results A total of 1877 patients were included in 10 RCTs.Meta-analysis results showed that the hemoglobin levels of the experimental group were higher than those of the control group on 14 and 28 days after treatment,and the differences were statistically significant (SMD=0.39,95%CI[0.18,0.60],P=0.0003;SMD=0.78,95%CI [0.59,0.96],P<0.000 01).There were no statistically significant differences in ferritin and 24 h hemoglobin levels between the two groups after treatment (SMD=0.47,95%CI[-0.56,1.50],P=0.37;SMD=0.31,95%CI[-0.32,0.94],P=0.33).Conclusion Intravenous injection of iron disaccharide can improve the hemoglobin levels at 14 and 28 days and improve the clinical effectiveness.However,due to the limitations of the quantity and quality of the included studies,the above conclusions need to be verified by more high-quality randomized controlled studies.
2020 Vol. 27 (21): 16-21 [Abstract] ( 40 ) HTML (52 KB)  PDF  (0 KB)  ( 6 )
22 Research progress of miRNA-381 in malignant tumors
XU Jie-huan； XIANG Lin；LI Yao-jun； DENG Yu-ping
miRNA is a kind of noncoding RNA,which plays a very important role in cell proliferation,apoptosis and differentiation.The miRNA-381 (hsa-miR-381) is a kind of new micrornas which is identified in recent years.The encoded gene,originally found in the stomach,which belongs to the miR-154 gene family,is on the long arm of chromosome 14.Several studies have shown that miR-381 has abnormal expression in lung cancer,liver cancer,colon cancer,malignant tumors and other osteosarcoma,which plays an important role in the occurrence and progress of tumor.This paper summarizes the research progress of miR-381 in multiple malignant tumors.
2020 Vol. 27 (21): 22-25 [Abstract] ( 42 ) HTML (37 KB)  PDF  (0 KB)  ( 6 )
26 Cardiovascular adverse reactions and medication monitoring of nonsteroidal anti-inflammatory drugs
Aodongtana
Non-steroidal anti-inflammatory drugs(NSAIDs)is a kind of common analgesic drug in clinic,but it has been reported that the incidence of adverse reactions is high in the long-term use of NSAIDs.Therefore,it is very important to study the mechanism of NSAIDs and find out the cause of adverse reactions in the course of using NSAIDs.At present,developed countries in Europe and the United States have issued a series of prevention and control guidelines or expert consensus on cardiovascular adverse reactions of NSAIDs,but the research on this area in China is still in its infancy.This paper mainly analyzes the cardiovascular adverse reactions and medication monitoring strategies of NSAIDs,so as to provide reference for medical workers to make comprehensive decisions.
2020 Vol. 27 (21): 26-29 [Abstract] ( 43 ) HTML (38 KB)  PDF  (0 KB)  ( 8 )
30 Application effect of massaging Wuxin acupoint in the process of awakening patients under general anesthesia
QIU Feng-min； WANG Xu-ping； ZHANG Wen-wen
Objective To explore the application effect of massaging Wuxin acupoint in process of awakening patients with general anesthesia. Methods From July 2018 to December 2019,60 patients who underwent general anesthesia were selected as study subjects,and were divided into control group (30 patients,conventional method of awakening)and oberservation (30 patients,massage Wuxin acupoint) according to the method of random number table method.The resuscitation scores,clinical indicators and complications of the two groups were compared. Results The scores of wakefulness,limb mobility and airway patency in the observation group were higher than those in the control group,with statistically significant differences (P<0.05).In the observation group,diastolic blood pressure,systolic blood pressure,heart rate were lower than those in the control group,and oxygen saturation was higher than that in the control group,with statistically significant differences (P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion It is of high clinical value to improve the clinical indexes and reduce the complications by massaging the Wuxin points in patients with general anesthesia.
2020 Vol. 27 (21): 30-32 [Abstract] ( 34 ) HTML (33 KB)  PDF  (0 KB)  ( 7 )
33 Therapeutic effect of Insulin Glargine combined with Acarbose on overweight type 2 diabetes mellitus
SHEN Cui-shan
Objectives To explore the therapeutic effect of Insulin Glargine combined with Acarbose on patients with overweight type 2 diabetes mellitus (T2DM).Methods A total of 42 patients with overweight T2DM admitted to our hospital from August 2016 to August 2019 were selected as the research objects.The selected patients were divided into the control group (21 cases) and the observation group (21 cases) according to random number table method.The control group was treated with Acarbose + Medium-acting Insulin,and the observation group was treated with Acarbose+ Insulin Glargine.After 2 months of continuous treatment,the total treatment efficiency,changes in glucose metabolism-related indexes,islet cell function,and hypoglycemia in the two groups were observed. Results After treatment,the total effective rate in the observation group (95.24%) was higher than that in the control group (71.42%),the difference was statistically significant (P<0.05).The fasting blood glucose (FBG),2 h postprandial blood glucose (2 h BG) and glycated hemoglobin (HbA1c) of the observation group were lower than those of the control group,the differences were statistically significant (P<0.05).The insulin secretion index (HOMA-β) in the observation group was higher than that in the control group,and the insulin resistance index (HOMA-IR) was lower than that in the control group,the differences were statistically significant (P<0.05).The incidence of hypoglycemia in the observation group (4.76%)was lower than that in the control group (28.57%),the difference was statistically significant (P<0.05).Conclusion For overweight T2DM patients,the clinical effect of Insulin Glargine combined with Acarbose is significant,which can effectively control blood sugar,improve islet cell secretion function,reduce hypoglycemia.
2020 Vol. 27 (21): 33-36 [Abstract] ( 32 ) HTML (37 KB)  PDF  (0 KB)  ( 7 )
37 Application of MRI phased array flexible coil and phased array cranial volume coil in the diagnosis of hypoxic ischemic encephalopathy in neonates
LU Guang-liang
Objective To investigate the application of magnetic resonance imaging (MRI) phased array flexible coil and phased array cranial volume coil in diagnosing hypoxic ischemic encephalopathy in neonates. Methods A total of 36 perinatal neonates with history of asphyxia hypoxic ischemic encephalopathy（HIE） admitted to Department of Imaging,the First People′s Hospital of Fuzhou City from April 2018 to April 2019 were selected as the research objects,and divided into group A (n=18) and group B (n=18) according to different examination methods.Group A was treated with MRI phased array flexible coil,and the group B was treated with MRI phased array cranial volume coil.The image quality evaluation indexes such as white matter noise ratio (SNR),gray matter SNR,gray-white matter SNR were compared,the rate of image clarity without artifact,and the diagnostic coincidence rate of the two groups of children.Results The white matter SNR,gray matter SNR and gray-white matter SNR of the children in group A were higher than those in group B,the differences were statistically significant (P<0.05).The rate of image clarity without artifact in group A was 94.44%,higher than 55.56% in group B,the difference was statistically significant (P<0.05).The diagnostic coincidence rate in group A was 88.89%,higher than 55.56% in group B,the difference was statistically significant(P<0.05).Conclusion Compared with MRI phased array cranial volume coil,the use of MRI phased array flexible coil is of higher image quality in the diagnosis of neonate HIE,which can improve the diagnosis rate and is worthy of clinical application.
2020 Vol. 27 (21): 37-39 [Abstract] ( 38 ) HTML (31 KB)  PDF  (0 KB)  ( 10 )
40 Clinical effect of psychological intervention combined with Flupentixol and Melitracen Tablets in the treatment of coronary geart disease complicated with anxiety disorder
LIU Rong
Objective To explore the clinical effect of psychological intervention combined with Flupentixol and Melitracen Tablets in the treatment of coronary heart disease complicated with anxiety disorder. Methods The clinical data of 90 patients with coronary heart disease complicated with anxiety disorder who were admitted and treated in our hospital from January 2018 to April 2019 were retrospectively analyzed.According to different treatment methods,they were divided into group A (30 cases),group B (30 cases) and group C (30 cases).Group A was treated with psychological intervention.Group B was treated with Flupentixol and Melitracen Tablets.Group C was treated with psychological intervention combined with Flupentixol and Melitracen Tablets.The clinical treatment effect and generalized anxiety disorder scale (GAD-7) scores were compared between the three groups. Results The total effective rate of treatment in group C was higher than that in groups A and group B,and the difference was statistically significant (P<0.05);there was no statistically significant difference in the efficacy between group A and group B (P>0.05);the GAD-7 scores in the three groups after intervention were lower than those in this group before intervention,and the differences were statistically significant (P<0.05);the GAD-7 score in group C was lower than that in group A and group B after intervention,and the differences were statistically significant (P<0.05).Conclusion Psychological intervention combined with Flupentixol and Melitracen Tablets has a good clinical effect in the treatment of coronary heart disease complicated with anxiety disorder,which can significantly reduce the level of anxiety in patients.
2020 Vol. 27 (21): 40-42转46 [Abstract] ( 31 ) HTML (33 KB)  PDF  (0 KB)  ( 6 )
43 Application effect of Isoniazid ultrasonic atomization in the patients with cavitary pulmonary tuberculosis and bronchial tuberculosis
ZHANG Dong
Objective To explore the application effect of Isoniazid ultrasonic atomization in the patients with cavitary pulmonary tuberculosis and bronchial tuberculosis. Methods The clinical data of 72 patients with cavitary pulmonary tuberculosis and bronchial tuberculosis admitted to our hospital from April 2017 to February 2019 were analyzed retrospectively.According to the treatment methods,the patients were divided into the group A (32 cases,only routine antituberculosis treatment) and the group B (40 cases,Isoniazid ultrasonic atomization while routine antituberculosis treatment).The negative conversion rates of tuberculosis,the closure rates of pulmonary cavity,clinical effect,pulmonary function and adverse reactions between the two groups of patients were compared. Results After 2 and 5 months of treatment in group B,the negative conversion rate of tuberculosis,the closure rate of pulmonary cavity and the total effective rate were all higher than those in group A,the differences were statistically significant (P<0.05).After treatment vital capacity (VC),maximum ventilation volume (MVV) and forced expiratory volume (FEV1)/forced vital capacity in the first second (FVC) in the two groups were higher than those before treatment,the differences were statistically significant (P<0.05),which each index in group B after treatment were higher than those in group A,and the differences were statistically significant (P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05).Conclusion Isoniazid ultrasonic atomization can improve the negative conversion rate and the closure rate of pulmonary cavity in the patients with cavitary pulmonary tuberculosis and bronchial tuberculosis,with ideal curative effect and improved pulmonary function,safe.
2020 Vol. 27 (21): 43-46 [Abstract] ( 38 ) HTML (36 KB)  PDF  (0 KB)  ( 6 )
47 Effect of continuous bedside renal replacement therapy on serum inflammatory factors and renal function in patients with severe pancreatitis
YOU Guo-ping
Objective To investigate the effect of continuous bedside renal replacement therapy (CRRT) on serum inflammatory factors and renal function in patients with severe pancreatitis (SAP).Methods From May 2015 to May 2019,82 patients with SAP treated in our hospital were selected as the study objects,and divided into group A (n=41)and group B (n=41) according to the random number table method.Group A received routine treatment+CRRT,group B received routine treatment.The clinical efficacy,inflammatory factors and renal function of the two groups were compared. Results The total effective rate of treatment in group A was 92.86%,higher than 76.19% in group B,the difference was statistically significant (P<0.05);the levels of interleukin-6 (IL-6) and creactive protein (CRP) in group A were lower than those in group B,the differences were statistically significant (P<0.05);the levels of serum amylase,urea nitrogen and creatinine in group A were (512.37±47.24) U/L,(6.18±2.17) μmol/L,(125.42±54.96) mmol/L,respectively,and those in group B were (683.49±83.10) U/L,(8.63±2.48) μmol/L,(336.67±64.85) mmol/L,the levels of serum amylase and urea nitrogen creatinine level and in group A were lower than those in group B,the differences were statistically significant (P<0.05).Conclusion CRRT can improve renal function,remove inflammatory mediators and improve prognosis in patients with SAP.
2020 Vol. 27 (21): 47-49 [Abstract] ( 41 ) HTML (31 KB)  PDF  (0 KB)  ( 6 )
50 Application comparison of painless electronic gastroscope and ordinary gastroscope in the removal of foreign bodies in children′s upper digestive tract
CHEN Liang-ren
Objective To explore the application of painless electronic gastroscope and ordinary gastroscope in the removal of foreign bodies in children′s upper digestive tract. Methods A total of 42 children with foreign bodies in the upper digestive tract admitted to our hospital from January 2017 to April 2019 were selected as the research objects.According to the random number table method,they were divided into control group (21 cases) and observation group(21 cases).The control group was treated with ordinary gastroscope,and the observation group was treated with painless electronic gastroscope.The success rate of foreign body removal,the hemodynamic changes at different time points during the perioperative period and the incidence of adverse reactions were compared between the two groups. Results The success rate of foreign body removal in the observation group (95.24%) was higher than that in the control group(71.43%),the difference was statistically significant (P<0.05).The mean arterial pressure (MAP) and heart rate (HR) of the children in the control group were higher than those before the operation,the MAP and HR in the observation group were lower than those before the operation,and lower than those in the control group,the differences were statistically significant (P<0.05).There were no significant differences in blood oxygen saturation (SpO2) between the two groups of children before the operation,intraoperative and postoperative (P>0.05).The total incidence of adverse reactions in the observation group (9.52%) was lower than that in the control group (47.62%),and the difference was statistically significant (P<0.05).Conclusion In children′s upper gastrointestinal foreign body removal,painless electronic gastroscope surgery has a high success rate of foreign body removal,has a small impact on hemodynamics,and has a low incidence of adverse reactions.
2020 Vol. 27 (21): 50-52转56 [Abstract] ( 31 ) HTML (33 KB)  PDF  (0 KB)  ( 6 )
53 Clinical effect of low-dose Azithromycin combined with Tiotropium Bromide Inhalation Powder Spray in the treatment of patients with chronic obstructive pulmonary disease in stable phase
LIU Xing-hua；YE Zhan-lan；LI Ai-fen
Objective To explore the clinical effect of Azithromycin combined with Tiotropium Bromide Inhalation Powder Spray in the treatment of patients with chronic obstructive pulmonary disease in stable phase. Methods Sixty patients with chronic obstructive pulmonary disease in stable phase received treatment from the department of respiratory medicine in our hospital from February 2016 to February 2019 were selected as the research subjects.They were divided into regular group (n=30) and experimental group (n=30) by random number table method.The patients in the regular group were treated with Tiotropium Bromide Inhalation Powder Spray,and the patients in the experimental group were treated with low-dose Azithromycin combiued with Tiotropium Bromide Inhalation Powder Spray.Treatment in each group lasted one month.Oxygen partial pressure,carbon dioxide partial pressure,forced expiratory volume in one second,one-second rate,peak expiratory flow,forced expiratory volume,and the ratio of forced expiratory volume in first second and forced expiratory volume,and therapeutic effect were compared in the two groups. Results After treatment,the oxygen partial pressure level of the experimental group was higher than that of the regular group,and the carbon dioxide partial pressure level was lower than that of the regular group,with statistically significant differences(P<0.05).In the experimental group,the forced expiratory volume in one second,one-second rate,peak expiratory flow,forced expiratory volume,and the ratio of forced expiratory volume in first second and forced expiratory volume were all higher than those in the regular group,and the differences were statistically significant (P<0.05).The total effective rate of the experimental group was higher than that of the regular group,and the difference was statistically significant (P<0.05).Conclusion The treatment of patients with with chronic obstructive pulmonary disease in stable phase by using lowdose Azithromycin combined with Tiotropium Bromide Inhalation Powder Spray can improve the lung function and enhance the therapeutic effect.
2020 Vol. 27 (21): 53-56 [Abstract] ( 39 ) HTML (36 KB)  PDF  (0 KB)  ( 6 )
57 Clinical effect of water-filtered infrared-A irradiation combined with Jingwanhong Ointment in the treament of diabetic pressure ulcers
MAI Feng-jiao； MENG Qing-qi； ZENG De-liang
Objective To investigate the clinical effect of water-filtered infrared-A irradiation combined with Jingwanhong Ointment in the treament of diabetic pressure ulcers. Methods A total of 60 patients with diabetic pressure ulcers admitted to the Department of Rehabilitation,Guangzhou Red Cross Hospital from March 2018 to September 2019 were selected as the research objects,dividing patients into two groups (n=30) according to the random number table method.All patients received routine treatment first,the patients in the control group was treated with Jingwanhong Ointment,the patients in observation group was treated with water-filtered infrared-A irradiation treatment on the basis of the control group,The clinical efficacy,clinical indicators,wound healing and quality of life of the two groups patients after treatment were observed and analyzed. Results The total effective rate in the observation group was 96.67%,which was higher than 80.00% in the control group,the difference was statistically significant (P＜0.05).In the observation group blister absorption time was (2.04±0.43) d,surface scab time was (3.16±0.46) d,pressure ulcer healing time was (8.13±1.07) d,which were shorter than (3.58±1.22),(5.16±1.51),(12.67±1.61) d in the control group,the number of dressing changes in the observation group was (9.25±2.07) times,fewer than (11.43±2.13) times in the control group,and the visual analogue scale (VAS) score of the observation group was (1.16±0.08) points,lower than that in the control group of(1.45±0.19) points,the differences were statistically significant (P＜0.05).The observation group′s pressure ulcer scale for healing (PUSH) and the World Health Organization Quality of Life Questionnaire-Brief Version (WHOQOL-Bref)scores before treatment were (7.85±1.16) and (51.16±7.59) points,the control group were (7.59±1.08) and (51.37±7.65)points,there were no significant differences between the two groups (P＞0.05).After treatment,the PUSH score of the observation group was (4.38±0.86) points,which was lower than (5.17±0.94) points in the control group,the WHOQOLBref score of the observation group was (65.18±8.73) points,higher than that of the control group of (60.07±7.86)points,the differences were statistically significant (P＜0.05).Conclusion Water-filtered infrared-A combined with Jingwanhong Ointment has better effect on diabetic pressure ulcers,can quickly improve symptoms,promote wound healing,reduce the number of dressing changes,reduce pain,and improve patients′ quality of life.
2020 Vol. 27 (21): 57-60 [Abstract] ( 44 ) HTML (38 KB)  PDF  (0 KB)  ( 7 )
61 Clinical effect of electro-nape acupuncture combined with five-element music therapy in the treatment of post-stroke depression
XIAO Yong-juan；LI Yu-lian
Objective To investigate the clinical effect of electro-nape acupuncture combined with five-element music therapy in the treatment of post-stroke depression (PSD).Methods Sixty patients with PSD who were admitted to the hospital from January 2018 to September 2019 were selected.They were divided into control group and treatment group by the random table method,each had 30 cases.The control group was treated with oral administration of Fluoxetine,while treatment group was treated with electro-nape acupuncture combined with five-element music therapy on the basis of the treatment of control group.The clinical effect,depression,activities of daily living scores before and after treatment were compared between the two groups. Results The total response rate of treatment group was higher than that of control group (P<0.05).After treatment,scores of Hamilton depression scale (HAMD) of both groups were lower than those before intervention,the differences were statistically significant (P<0.05),and HAMD score of treatment group was lower than that of control group,the difference was statistically significant (P<0.05).The activity of daily living (ADL) scores of both groups after treatment were higher than those before treatment,the differences were statistically significant (P<0.05),and ADL score of treatment group was higher than that of control group,the difference was statistically significant(P<0.05).Conclusion Electro-nape acupuncture combined with five-element music therapy is effective in the treatment of PSD,and it can effectively alleviate depressive symptoms of patients.
2020 Vol. 27 (21): 61-63 [Abstract] ( 45 ) HTML (32 KB)  PDF  (0 KB)  ( 5 )
64 Expression and clinical significance of serum ferritin level in patients with initial cerebral infarction
SUN Yu； HE Xing-Ling； YANG Shui-quan
Objective To explore the expression and clinical significance of serum ferritin level in patients with initial cerebral infarction. Methods A total of 117 patients with cerebral infarction from October 2017 to August 2019 were selected as the observation group and 117 healthy people as the control group.Serum samples were obtained on 1,3,5,7,14 d and 28 d to detect the levels of hepcidin,observation group were further divided into light group (n=42)，moderate group (n=41) and heavy group (n=34) according to their NIHSS scores.The modified Rankin scale (mRS) was evaluated at 3 months after cerebral infarction.According to the mRS scores,the patients were divided into good prognosis group (n=64) and poor prognosis group (n=53).The changes of serum ferritin level were compared between the observation group and the control group at different time points.The relationship between serum hepcidin level and neurological deficit and prognosis in the observation group was analyzed. Results The levels of serum ferritin in the observation group were higher than those in the control group on the 1,3,5,7,14 d and 28 d after the onset of the disease (P<0.05).The levels of light,moderate and heavy serum ferritin in the observation group were higher than those in the control group,and the levels of moderate and heavy serum ferritin were higher than those in the light group,the level of heavy serum ferritin was higher than that in the moderate group,and the differences were statistically significant (P<0.05).In the observation group,the levels of serum ferritin water on the 1,3,5,7,14 d and 28 d after the onset of the disease were lower than those of the patients with poor prognosis,the differences were statistically significant(P<0.05).Conclusion After cerebral infarction,the expression of serum ferritin increased,and the more serious the degree of neurological impairment,the worse the prognosis,the more obvious the expression,the level of serum ferritin is closely related to the occurrence,severity and prognosis of cerebral infarction.
2020 Vol. 27 (21): 64-66 [Abstract] ( 28 ) HTML (34 KB)  PDF  (0 KB)  ( 5 )
67 Application effect of Lamotrigine in patients with trigeminal neuralgia
CAO Dan
Objective To investigate the effect of application of Lamotrigine in patients with trigeminal neuralgia.Methods A total of 134 patients with trigeminal neuralgia who were treated in our hospital from June 2011 to June 2016 were selected as the subjects of the research.All the patients were divided into the Lamotrigine group and Carbamazepine group according to the random number table method,with 67 cases in each group.Patients in the Lamotrigine group acceped Lamotrigine Dispersible Tablets,and patients in the Carbamazepine group acceped Carbamazepine orally.The pain visual analogue scale (VAS) was used to evaluate the pain degrees of the patients.The quality of life scale for patients with trigeminal neuralgia was also adopted for assessment of their quality of life before and after treatment.The curative effect and adverse reactions of the two groups of patients were compared. Results Before treatment,there was no significant difference in VAS between the two groups (P>0.05);after treatment,the VAS score of the two groups was lower than before,and the VAS score of the Lamotrigine group was lower than that of the Carbamazepine group,the difference was statistically significant (P<0.05).Before treatment,there was no statistically significant difference between the dimensions and total scores of the two groups of patients on the quality of life scale (P>0.05);after treatment,the dimensions and total scores of the two groups of patients were lower than those before treatment,the dimensions and total scores of the quality of life scale of patients in the Lamotrigine group were lower than those in the carbamazepine group,and the differences were statistically significant (P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05).Conclusion Lamotrigine has a good application effect in patients with trigeminal neuralgia,which can effectively alleviate pain and improve the patients′ quality of life.
2020 Vol. 27 (21): 67-69 [Abstract] ( 33 ) HTML (31 KB)  PDF  (0 KB)  ( 10 )
70 Effect of Venlafaxine Hydrochloride Sustained-release Tablets combined with psychotherapy in patients with depression
QU Xian-ling
Objective To explore the effect of Venlafaxine Hydrochloride Sustained-release Tablets combined with psychotherapy in patients with depression. Methods A total of 75 inpatients and outpatients admitted to our hospital from January 2017 to February 2018 were selected as research objects.According to the random number table method,they were divided into three groups,25 cases in each group.Group 1 was given Venlafaxine Hydrochloride Sustained-release Tablets,group 2 was given psychological intervention,and group 3 was given Venlafaxine Hydrochloride Sustained-release Tablets combined with psychological intervention.The changes of sleep quality and mental state of the three groups before and after treatment were compared. Results The anxiety self-assessment chat and depression selfassessment scale scores of patients in group 3 after treatment were lower than those of group 1 and group 2,the differences were statistically significant (P<0.05).The Pittsburgh sleep quality index scores were lower than those in group 1 and group 2,and the differences were statistically significant (P<0.05).Conclusion The combination of Venlafaxine Hydrochloride Sustained-release Tablets and psychological treatment can effectively reduce the patients′ depression symptoms,effectively improve the patients′ living condition,and accelerate the patients′ recovery.
2020 Vol. 27 (21): 70-72 [Abstract] ( 35 ) HTML (30 KB)  PDF  (0 KB)  ( 7 )
73 Application effect of antiplatelet drugs in patients with cerebral infarction before thrombolysis
GUO Wei； XUE Hui-fang； WEI Shu-zhen； REN Shu-ting
Objective To explore the therapeutic effect and prognosis of patients with cerebral infarction (CI) taking antiplatelet drugs before thrombolysis. Methods A total of 120 patients with CI who were admitted to the hospital from January 2017 to May 2019 were selected as the subjects.They were divided into the observation group and the control group according to the use of antiplatelet drugs before thrombolysis，each had 60 cases.Before thrombolysis,the observation group took antiplatelet drugs while the control group did not take.Both groups were treated with thrombolysis therapy.The curative effect at 1 d and 7 d after treatment,blood pressure,intracranial hemorrhage and 90 day prognosis were compared between the two groups. Results The excellent and good rates in the observation group at 1 d and 7 d after treatment (63.33% and 70.00%) were higher than those in the control group (40.00% and 45.00%).The differences were statistically significant (P<0.05).After treatment,the blood pressure of observation group was lower than that of control group,the difference was statistically significant (P<0.05).There were no significant differences in the good rate of 90 day prognosis,mortality rate or rate of intracranial hemorrhage between the two groups (P>0.05).Conclusion The short-term effect of taking antiplatelet drugs before thrombolysis is good in the treatment of patients with CI.It can significantly improve the blood pressure of patients,without increasing the incidence of intracranial hemorrhage or causing obvious influence on the prognosis.
2020 Vol. 27 (21): 73-75 [Abstract] ( 34 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
76 Clinical effect of Vinpocetine in the treatment of chronic cerebral insufficiency
ZHANG Li-min
Objective To investigate the clinical effect of Vinpocetine on patients with chronic cerebral insufficiency.Methods Forty-two patients with chronic cerebral insufficiency who were treated in our hospital from May 2016 to May 2019 were randomly divided into the control group and the observation group by lottery,each group had 21 patients,on the bases of conventional treatment,the control group accepted Ginkgo Damamo Injection,and the observation group accepted Vnpocetine,and the clinical effectiveness,blood flow rate and adverse reactions before and after treatment were compared between the two groups. Results The total clinical effective rate of the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05).There was no significant difference in blood flow velocity of patients between the two groups before treatment,the difference was not statistically significant (P>0.05).The blood flow velocity after treatment was faster than that of the control group,the difference was statistically significant (P<0.05).The total incidence of adverse reactions was lower than that of the control group,the difference was statistically significant (P<0.05).Conclusion Vinpocetine can improve the clinical efficiency of patients with chronic cerebral insufficiency,and the adverse drug reactions are small,which is worth promoting.
2020 Vol. 27 (21): 76-78 [Abstract] ( 31 ) HTML (31 KB)  PDF  (0 KB)  ( 6 )
79 Clinical effect of Aripiprazole in the treatment of epileptic mental disorders
MA Chun-li； XU Tian-ying
Objective To investigate the clinical effect of Aripiprazole in the treatment of epileptic mental disorders.Methods From January to December in 2018,60 epileptic patients with mental disorders were selected as the research objects,and divided into experimental group and control group according to the dice rolling method,each had 30 cases.The control group was treated with Perphenazine and the experimental group with Aripiprazole.The clinical efficacy,positive and negative symptoms scale (PANSS) score,mini-mental tate examination scale (MMSE) score,Hamilton Anxiety Scale (HAMA) score,Hamilton depression scale (HAMD) and quality of life score of the two groups were compared before and after treatment. Results The total effective rate of the experimental group was higher than that of the control group,the difference was statistically significant (P<0.05).There was no significant difference in PANSS between the two groups before treatment (P>0.05).After treatment,the scores of general psychopathology,positive symptoms,negative symptoms and total scores in the experimental group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the scores of MMSE and quality of life in the experimental group were higher than those in the control group,and the scores of HAMA and HAMD were lower than those in the control group,the differences were statistically significant (P<0.05).Conclusion Aripiprazole is more effective in the treatment of mental disorders caused by epilepsy,and it can effectively improve the symptoms and signs of patients,improve the mental state and mental state of patients,and improve the quality of life of patients.
2020 Vol. 27 (21): 79-81 [Abstract] ( 41 ) HTML (32 KB)  PDF  (0 KB)  ( 7 )
82 Analysis of short-term efficacy and discussion on postoperative rehabilitation methods of artificial bipolar femoral head replacement in treatment of senile femoral neck fracture
XIONG Jun-wei； LI Huai-qiang； TAN Juan
Objective To investigate the short-term efficacy and its postoperative rehabilitation methods of artificial bipolar femoral head replacement (BFHR) in the treatment of senile femoral neck fracture. Methods A total of 80 patients with displaced femoral neck fracture who admitted in the hospital from August 2017 to December 2018 were selected as the research objects,and they were divided into control group (40 cases) and observation group (40 cases) according to the random number table method.Two groups were treated with BFHR,control group was given routine nursing,and observation group was given early rehabilitation training.The surgical indexes,hip joint function,quality of life,and the total incidence of complications were compared between two groups. Results There were no statistically significant differences between the two groups in operation time,intraoperative blood loss,postoperative drainage,length of hospital stay,and off-bed walking time (P>0.05).Twelve months after surgery,the Harris score in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05).Harris scores in both groups at 12 months after surgery were lower than those at 6 months after surgery,and the differences were statistically significant (P<0.05).The scores of physiological function,physiological limitation,physical pain,role emotional,social function and general health in observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).The total incidence of postoperative complications in observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion BFHR in treatment of senile displaced femoral neck fracture has better short-term recovery effect.Early rehabilitation training can promote recovery of hip joint function,improve quality of life and have lower incidence of complications.It is worth popularizing in clinical application.
2020 Vol. 27 (21): 82-85 [Abstract] ( 41 ) HTML (35 KB)  PDF  (0 KB)  ( 13 )
86 Application of direct anterior approach in patients with degenerative hip arthritis undergoing total hip arthroplasty
CHEN Wen-hui
Objective To evaluate the application effect of direct anterior approach in patients with degenerative hip arthritis undergoing total hip arthroplasty. Methods A total of 30 patients with degenerative hip arthritis of the hip who underwent total hip arthroplasty in our hospital from January to October 2019 were selected as the study subjects for retrospective analysis.The patients were divided into observation group and control group according to different surgical approaches,with 15 cases in each group.The observation group was treated by direct anterior approach while the control group was treated by posterolateral approach.The two groups were given oral Livaroxaban 10 mg qd for anticoagulant therapy 24 hours after operation.The operation time,intraoperative blood loss,postoperative pain score and Harris hip joint function score between the two groups were compared. Results The operation time in observation group was shorter than that in control group,and the difference had statistical significance (P<0.05).The intraoperative blood loss in observation group was less than that in control group,and the difference had statistical significance (P<0.05).The pain scores at 1,4 and 12 weeks after operation in observation group were lower than those in control group,and the differences had statistical significance (P<0.05).The Harris hip joint function scores at 1,4 and 12 weeks after operation in observation group were higher than those in control group,and the difference had statistical significance (P<0.05).Conclusion Direct anterior approach can significantly shorten the operation time,reduce the intraoperative blood loss,reduce the pain after total hip arthroplasty,and promote the functional recovery after total hip arthroplasty.
2020 Vol. 27 (21): 86-88转92 [Abstract] ( 35 ) HTML (34 KB)  PDF  (0 KB)  ( 7 )
89 Clinical effect of percutaneous vertebroplasty in the treatment of senile osteoporotic thoracolumbar compression fracture
YANG Hong-zhi；XIONG Liang-yu；HU Bin；YANG Yong-hua； WANG Xi-chun； GAO Zhan-wang1
Objective To investigate the clinical effect of percutaneous vertebroplasty in the treatment of osteoporotic thoracolumbar compression fractures in the elderly. Methods A total of 50 elderly patients with osteoporotic thoracolumbar compression fractures in Jiujiang First People′s Hospital from January 2017 to June 2019 were divided into two groups according to the random drawing method.The control group was treated with routine reduction and the study group was treated with percutaneous vertebroplasty.The therapeutic effect,score of low back pain (ODI) before and after treatment,visual analogue scale (VAS) score before and after treatment,vertebral body recovery after treatment and complications after treatment were compared between the two groups. Results The total effective rate of clinical treatment in the study group was higher than that in the control group (P<0.05).The ODI scores of 3,7 and 14 days after treatment in the study group were lower than those in the control group (P<0.05).The VAS scores of 3,7 and 14 days after treatment in the study group were lower than those in the control group (P<0.05).The Cobb angle of the study group was lower than that of the control group (P<0.05).The posterior edge height,midline height and anterior edge height of the study group were higher than those of the control group (P<0.05).The total incidence of complications after treatment in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The clinical effect of percutaneous vertebroplasty in the treatment of osteoporotic thoracolumbar compression fractures in the elderly is accurate.
2020 Vol. 27 (21): 89-92 [Abstract] ( 45 ) HTML (38 KB)  PDF  (0 KB)  ( 8 )
93 Application value of early active functional exercise across pain threshold in patients with femoral neck fracture
ZHAO Li
Objective To explore the application value of early active functional exercise across pain threshold with femoral neck fracture. Methods A total of 80 cases with femoral neck fracture in our hospital from January 2018 to January 2019 were randomly divided into two group,40 cases in each group.The observation group implemented the nursing intervention of active functional exercise across pain threshold in early stage,the control group used routine nursing.Then the ultrasound result of lower limb vessels in the two groups were compared，the hip joint score in the two group after intervention and the overall recovery situation,such as postoperative hospitalization time,postoperative crutch walking time and disposable crutch independent walking time were compared. Results After intervention,ultrasound results showed that the reflux patency rate in the observation group was higher than that in control group,the proportion of complete vascular occlusion was significantly lower than that in control group,the differences were statistically significant (P<0.05).Harris score of hip joint was significantly higher than that in control group,the difference was statistically significant (P<0.05),the hospitalization time in the observation group was shorter than that in control group,the walking time of crutches and disposable crutches were earlier than those in control group,the differences were statistically significant (P<0.05),and the total nursing satisfaction in the observation group was significantly higher than that in control group,the difference was statistically significant (P<0.05).Conclusion Nursing intervention for patients with femoral neck fracture through early cross-pain threshold active functional exercise has great significance to improve and reduce the vascular occlusion,so it can improve the postoperative joint function and promote the postoperative recovery.
2020 Vol. 27 (21): 93-96 [Abstract] ( 42 ) HTML (35 KB)  PDF  (0 KB)  ( 7 )
97 Clinical effect of laparoscopic internal ring repair in the treatment of children with indirect inguinal hernia
CHEN Wei-long； DENG Qing-qiang； XU Wei
Objective To investigate the clinical effect of laparoscopic internal ring repair in the treatment of children with indirect inguinal hernia. Methods A total of 95 children with indirect inguinal hernia who were admitted to our hospital from June 2018 to October 2019 were selected as research subjects,and they were divided into control group(n=45) and observation group (n=50) according to random number table method.The control group underwent conventional external inguinal ring high ligation of hernia sac,and observation group was treated with laparoscopic internal ring repair.The operation time,hospital stays and the incidence of hematoma of scrotum were compared between the two groups. Results The operation time and hospital stays in observation group were shorter than those in control group,with statistical differences (P<0.05).The incidence of hematoma of scrotum in observation group was lower than that in control group,with statistical difference (P<0.05).The total effective rate of observation group was higher than that of control group,with statistical difference (P<0.05).Conclusion Laparoscopic internal ring repair in treatment of children with indirect inguinal hernia has significant effect,it can shorten operation time and hospital stays,decrease the incidence of postoperative hematoma of scrotum,and benefit the children.
2020 Vol. 27 (21): 97-99 [Abstract] ( 38 ) HTML (32 KB)  PDF  (0 KB)  ( 7 )
100 Study on the safety and bad psychological state of painless gastroscope in children
XIAO Chen； ZENG Kai； ZHANG Yi； LUO Li
Objective To explore the safety and bad psychological status of painless gastroscopy in children. Methods From January 2019 to January 2020,60 patients with foreign bodies in the upper digestive tract with complete medical records were selected as the subjects,they were divided into control group and experimental group according to random number table method,30 cases in each group.The patients in the control group were treated with general gastroscope,and the patients in the experimental group were treated with painless gastroscope.The mean arterial pressure (MAP),blood oxygen saturation (SpO2),spence children′s anxiety scale (SCAS) score,foreign body removal effect and adverse reactions were observed before and after operation. Results The MAP level in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).There was no significant difference in map between the two groups before and after operation (P＞0.05).There was no significant difference in SpO2 between the two groups before,during and after operation (P＞0.05).The SCAS score of the observation group was lower than that of the control group,the time of extraction was shorter than that of the control group,and the success rate of one-time extraction was higher than that of the control group,the differences were statistically significant (P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion Painless gastroscopy can improve the MAP level and SCAs score of children,improve the success rate of one-time removal,and reduce the incidence of adverse reactions,which is worthy of clinical recommendation.
2020 Vol. 27 (21): 100-102 [Abstract] ( 34 ) HTML (33 KB)  PDF  (0 KB)  ( 9 )
103 Clinical efficacy study of Montelukast Sodium of leukotriene receptor antagonist on acute asthmatic bronchitis in children
WU Zhuo-jian； ZHONG Mei-gong； TAN Wen-qiang；LI Jun-wen； XU Jie；LIANG Fa-liang；FENG Yue-hua
Objective To investigate the clinical efficacy of Montelukast Sodium of leukotriene receptor antagonist on children with acute asthmatic bronchitis. Methods A total of 80 children with acute asthmatic bronchitis admitted to our hospital from January 2018 to June 2019 were selected and divided into the observation group (40 cases) and the control group (40 cases) according to the different treatment methods.The control group was treated with routine treatment,the observation group was treated with Montelukast Sodium of leukotriene receptor antagonist on this basis.The clinical efficacy,the time of clinical symptom relief,the recurrence rate of wheezing,inflammatory mediators and the safety of treatment were compared between the two groups. Results The total effective rate of the observation group was 95.00%,which was higher than that of the control group (77.50%),the difference was statistically significant (P＜0.05).The recurrence rate of wheezing was 5.00% in the observation group within 6 months after treatment,which was lower than 25.00% in the control group,the difference was statistically significant (P＜0.05).The wheezing relief time,wheezing disappeared time,cough subsided time and hospitalization time in the observation group were shorter than those in the control group,the levels of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) of the observation group were lower than those of the control group,the differences were statistically significant (P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion The treatment of Montelukast Sodium of leukotriene receptor antagonists in children with acute asthmatic bronchitis can effectively improve the clinical efficacy,promote the relief of clinical symptoms,improve the inflammatory response,reduce the recurrence of asthma,and have a high safety.
2020 Vol. 27 (21): 103-105 [Abstract] ( 35 ) HTML (35 KB)  PDF  (0 KB)  ( 9 )
106 Application of cervical injection of Pituitrin and Oxytocin combined with uterine aspiration + hysteroscopy in type Ⅰ-Ⅱscar pregnancy
DENG Shu-lan
Objective To explore the application effect of cervical injection of Pituitrin and Oxytocin combined with uterine aspiration + hysteroscopy in type Ⅰ-Ⅱscar pregnancy. Methods A total of 98 patients with type Ⅰ-Ⅱscar pregnancy who were admitted to our hospital from August 2018 to December 2019 were selected as research subjects.According to the random number table method,the patients were divided into observation group and control group,with 49 cases in each group.The control group was given removal of transvaginal scar pregnancy lesions under epidural anesthesia,and the study group was given cervical injection of Pituitrin and Oxytocin combined with uterine aspiration+ hysteroscopy.The intraoperative blood loss,surgery time,negative conversion time of blood human chorionic gonadotropin (HCG),length of hospital stay,hospitalization cost and complications were compared between the two groups. Results The intraoperative blood loss in the observation group was less than that in the control group,the surgery time and the negative conversion time of blood HCG were shorter than those in the control group,the differences were statistically significant (P<0.05).The length of hospital stay in the observation group was shorter than that in the control group,and the hospitalization cost was less than that in the control group,the differences were statistically significant (P<0.05).The total incidence rate of complications in the observation group was 4.08%,which was lower than 16.33% in the control group,and the difference was statistically significant (P<0.05).Conclusion Cervical injection of Pituitrin and Oxytocin combined with uterine aspiration + hysteroscopy in the treatment of type Ⅰ-Ⅱscar pregnancy has a significant effect,which can shorten the treatment time and reduce bleeding,and there is no surgical incision and fewer complications,which is worthy of clinical promotion and application.
2020 Vol. 27 (21): 106-108 [Abstract] ( 36 ) HTML (33 KB)  PDF  (0 KB)  ( 7 )
109 Effect of chiropractic combined with vibroacoustic therapy in the treatment of 3-5-year-old children with growth retardation
WU Dong-liang； GUAN Chu-qiao； DU Jie； PAN Quan-guan
Objective To explore the effect of chiropractic combined with vibroacoustic therapy (VAT) in the treatment of 3-5-year-old children with growth retardation. Methods A total of 80 cases of 3-5-year-old children with growth retardation admitted to our hospital in March 2017 were selected as the research objects.According to the method of random number table,they were divided into the control group (n=40) and the observation group (n=40).The control group was treated with routine treatment,while the observation group was treated with chiropractic combined with VAT on the basis of the control group.The height changes in different periods,motor function improvement and development index of the two groups before and after treatment were compared. Results The height of children in the observation group at the 3rd,6th,9th and 12th month after treatment was higher than that in the control group,the difference was statistically significant (P＜0.05).There were no significant difference in motor function,mental development index (MDI)and psychomotor development index (PDI) before treatment between the two groups (P＞0.05).After treatment,the level of gross motor (GM) function and fine motor (FM) function in the observation group were higher than those in the control group,the differences were statistically significant (P＜0.05).The levels of PDI and MDI in the observation group after treatment were higher than those in the control group,the differences were statistically significant (P＜0.05).Conclusion For children with growth retardation,chiropractic therapy combined with VAT can promote their height growth,improve their neuromotor function,and ensure their healthy growth and development.
2020 Vol. 27 (21): 109-112 [Abstract] ( 39 ) HTML (35 KB)  PDF  (0 KB)  ( 7 )
113 Clinical effect of transvaginal ovarian cyst puncture under the guidance of B-ultrasound in the treatment of infertility with ovarian cyst
ZHENG Juan； HUANG Xiao-rong； DAI Xue-ying
Objective To study the clinical effect of transvaginal ovarian cyst puncture under the guidance of B ultrasound in the treatment of infertility with ovarian cyst. Methods A total of 53 infertile patients with ovarian cyst were selected treated in the Fourth People′s Hospital of Liaocheng City from December 2017 to December 2018.By random number table method,patients were divided into group A (n=26) and group B (n=27).Group A was treated with ovulation induction,and group B was treated with ovulation induction+puncture of ovarian cyst.Ovulation induction,clinical effect,adverse reaction between two groups were compared. Results The dosage of Urotropin (HMG) in group B was less than that in group A,the days of medication and follicular period in group B were shorter than that in group A,the pregnancy rate in group B was higher than that in group A,the total effective rate of clinical treatment in group B was higher than that in group A,the differences were statistically significant (P<0.05).There was no significant difference between the two groups in the total incidence of adverse reactions such as infection,pelvic adhesion (P＞0.05).Conclusion In the treatment of infertility with ovarian cyst,transvaginal ovarian puncture under the guidance of B ultrasound can reduce the dosage of HMG,shorten the days of medication and follicular period,and improve the pregnancy rate.The clinical effect is significant.
2020 Vol. 27 (21): 113-115 [Abstract] ( 40 ) HTML (32 KB)  PDF  (0 KB)  ( 8 )
116 Application effect of Erythropoietin on neonatal hypoxic-ischemic encephalopathy
FENG Yan
Objective To investigate the application effect of Erythropoietin （EPO） on neonatal hypoxic-ischemic encephalopathy (HIE).Methods A total of 80 patients HIE with EPO treated in our hospital from March 2016 to September 2018 were selected and divided into control group and observation group by random number table method,40 cases in each group.The control group was given conventional treatment,and the observation group was given EPO treatment on the basis of the control group.After treatment,the therapeutic effect,the newborn′s neurobehavioral development,intellectual development and birth quality between the two groups were compared. Results The total effective rate in the observation group was 95.00% (38/40),higher than that of the control group,accounting for 77.50% (31/40),and the difference was statistically significant (P=0.023).The 2 and 4 week neonatal behavioral neurological assessment(NBNA) scores in the observation group were higher than those of the control group,and the differences were statistically significant (P<0.05).At 3 and 6 months after birth,the psychological development index (PDI) score and mental development index (MDI) score of the observation group were higher than those of the control group,and the differences were statistically significant (P<0.05).After the age of 10 months,the scores of psychomotor function area,gross motor function area,language function area,social adaption function area,and personal social contact function area in the observation group were higher than those of the control group,the differences were statistically significant (P<0.05).Conclusion The use of EPO treatment for HIE is beneficial to promoting the recovery of neurological function,ameliorating intellectual development,and improving birth quality.It is worthy of clinical promotion.
2020 Vol. 27 (21): 116-118 [Abstract] ( 40 ) HTML (33 KB)  PDF  (0 KB)  ( 7 )
119 Clinical effect of Dexamethasone in the treatment of lobar pneumonia
ZHAO Na
Objective To explore the clinical effect of Dexamethasone (DMXS) in the treatment of lobar pneumonia.Methods A total of 102 children with lobar pneumonia treated in our hospital from June 2018 to June 2019 were selected as subjects and divided into two groups through stratified sampling method,51 cases in each group.The control group received routine treatment measures such as anti infection,cough and asthma relief;on the basis of routine treatment,the study group took DMXS.The curative effect,symptom relief time,hospital stays and inflammatory factors were compared between the two groups. Results The total effective rate in the study group (92.16%) was higher than that of control group (78.43%),with statistical difference (P<0.05);the relief time of symptoms like high fever,cough and lung rale,hospital stays in the study group were shorter than those of control group,with statistical differences (P<0.05).Before treatment,tumor necrosis factor-α(TNF-α),interleukin-8(IL-8)and interleukin-6(IL-6)between groups showed no statistically significant differences (P＞0.05),after treatment,the levels of TNF-α,IL-8 and IL-6 in the study group were lower than those of control group,with statistical differences (P<0.05).Conclusion DMXS can shorten the symptom relief time,improve the inflammatory index and treatment effect,and promote children′s fast recovery.
2020 Vol. 27 (21): 119-121转125 [Abstract] ( 36 ) HTML (33 KB)  PDF  (0 KB)  ( 10 )
122 Effect and safety of high-intensity focused ultrasound in the treatment of uterine incision pregnancy
HE Jie；LIN An-ping； DU Mei；GAN Xiao-ling
Objective To investigate the efficacy and safety of high intensity focused ultrasound (HIFU) in the treatment of uterine incision pregnancy. Methods A total of 130 patients undergoing uterine incision pregnancy who were treated in the Department of Obstetrics and Gynecology of the Second People′s Hospital of Jiulongpo District of Chongqing City from December 2015 to December 2018 were selected as the research subjects,and they were divided into the control group (65 cases) and the observation group (65 cases) according to the random number table method.The control group was treated with uterine artery embolization,and the observation group was treated with HIFU.Perioperative indicators,β-human chorionic gonadotropin (β-HCG) levels,and adverse events were compared between the two groups of patients. Results The time to return to normal β-HCG,the number of hospital stays in the observation group were shorter than those in the control group,and vaginal bleeding in the observation group was less than that in the control group,and the differences were statistically significant (P＜0.05).After 5 days of treatment,the blood β-HCG level in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The total incidence of adverse events in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion HIFU is effective in treating uterine incision pregnancy,it can shorten the length of hospital stay,reduce vaginal bleeding,promote the recovery of blood β-HCG levels,and reduce the incidence of postoperative adverse events,which is worthy of clinical promotion.
2020 Vol. 27 (21): 122-125 [Abstract] ( 32 ) HTML (35 KB)  PDF  (0 KB)  ( 6 )
126 Clinical effect comparison of the Oxycodone Hydrochloride Sustained-release Tablets and Tramadol Hydrochloride Sustained-release Tablets in the treatment of moderate cancer pain
CHEN Cai-xia
Objective To compare the clinical effect of Oxycodone Hydrochloride Sustained-release Tablets and Tramadol Hydrochloride Sustained-release Tablets in the treatment of moderate cancer pain. Methods From January 2014 to December 2018,100 patients with moderate cancer pain were selected as subjects and randomly divided into control group (n=50) and study group (n=50).The patients in the control group were treated with Tramadol Hydrochloride Sustained-release Tablets,and the patients in the study group were treated with Oxycodone Hydrochloride Sustained-release Tablets.The analgesic effect,quality of life scores before and after treatment and adverse reactions were compared between the two groups. Results The total effective rate of analgesia in the study group was 96.00%,which was higher than that in the control group (82.00%),the difference was statistically significant (P<0.05).The incidence rates of constipation,nausea,dizziness,lethargy and dysuria in the study group were 14.00%,16.00%,2.00%,6.00% and 2.00%,respectively,which were not significantly different from those in the control group (16.00%,14.00%,8.00%,4.00%,P>0.05).Before treatment,the appetite score of the study group was (1.75±0.55) points,mental state score of the study group was (1.65±0.70) points,sleep score of the study group was (1.80±0.65) points and daily living ability score of the study group was (1.95±0.70) points,compared with the control group [(1.70±0.60),(1.60±0.75),(1.85±0.60),(1.90±0.75) points],there were no significant differences between the two groups (P>0.05).The scores of quality of life after treatment in the two groups were higher than those before treatment,and the differences were statistically significant (P<0.05).After treatment,the appetite score of the study group was (3.80±0.35) points,mental state score of the study group was (4.25±0.60) points,sleep score of the study group was (4.10±0.70) points and daily living ability score of the study group was (3.15±0.60) points,compared with the control group [(3.65±0.40),(4.15±0.55),(3.95±0.85),(3.05±0.45) points],there were no significant differences between the two groups (P>0.05).Conclusion The clinical effect of Oxycodone Hydrochloride Sustained-release Tablets in the treatment of moderate cancer pain is accurate,which can effectively improve the quality of life after treatment and improve the clinical efficacy,and the incidence of adverse reactions is not increased,so it has important clinical application value.
2020 Vol. 27 (21): 126-129 [Abstract] ( 38 ) HTML (34 KB)  PDF  (0 KB)  ( 8 )
130 Effect comparison between Amlodipine Besylate and Levamlodipine Besylate in the treatment of hypertension
WANG Yun
Objective To compare the effect of Amlodipine Besylate and Levamlodipine Besylate in the treatment of hypertension. Methods From January 2018 to May 2019,80 cases of patients with hypertension treated in our hospital were selected as subjects,they were divided into two groups according to the random number table method,40 cases in each group.The control group was given Amlodipine Besylate,while the observation group was given Levamlodipine Besylate.The clinical efficacy,blood pressure level,blood pressure variability,vascular endothelial function and total incidence of adverse reactions were compared. Results The total clinical effective rate of the observation group was higher than that of the control group,the difference was statistically significant (P<0.05).After treatment,the systolic blood pressure,diastolic blood pressure,morning peak of blood pressure,standard deviation of systolic blood pressure and systolic blood pressure variation index in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).After treatment,the level of nitric oxide in the observation group was lower than that in the control group,and the level of endothelin-1 in the observation group was higher than that in the control group,the differences were statistically significant (P<0.05).The total incidence of adverse reactions was compared between the two groups,the difference was not statistically significant (P>0.05).Conclusion Levamlodipine Besylate is superior to Amlodipine Besylate in the treatment of hypertension.The incidence of adverse reactions between Levamlodipine Besylate and Amlodipine Besylate is similar,and both have good medication safety.
2020 Vol. 27 (21): 130-133 [Abstract] ( 38 ) HTML (36 KB)  PDF  (0 KB)  ( 8 )
134 Analysis on the use of cardio-cerebrovascular blood regulating agents in outpatient pharmacy of our hospital from 2017 to 2019
HONG Huai-zhang； ZHUO Shao-hua； QIU Yuan-cong； HUANG Xin-wei
Objective To understand the use of cardio-cerebrovascular blood-regulating agents (hereinafter referred to as "blood-regulating agents") in Huizhou First People′s Hospital from 2017 to 2019,so as to provide reference for clinical rational drug use. Methods The relevant data of "blood-regulating agents" from 2017 to 2019 were extracted from the information HIS system of our hospital,and the defined daily dose (DDD) and drug sum recommended by World Health Organization were used to analyze the annual sales,annual growth rate,medication frequency (DDDs),ranking ratio (B/A) and defined daily cost (DDC) of "blood-regulating agents". Results From 2017 to 2019,the annual sales for"blood regulating agents" in our hospital were 3.4349,3.8983 and 4.2823 million yuan respectively,accounting for 3.35%,3.51% and 3.21% of the total amount of drugs in the hospital,respectively,compared with 2017 and 2018.The growth rates were 13.5% and 9.85% respectively.The annual growth rate of "blood management agents" was 13.50% in 2018 and 9.85% in 2019.The top three sales amount of single variety were Shexiang Baoxin Pills,Xinkeshu Tablets and Naosuantong Capsules.In the order of DDDs,the medication frequency of Xuesaitong Capsules,Quick-acting Heart-saving Pills,Ginkgo Ketone Ester Dropping Pills and Maixuekang Enteric-coated Tablets changed greatly,but the frequency of other drugs was basically stable.The DDC value remained basically stable,and drug prices were stable in the past three years. Conclusion The application of "blood-regulating agent" in our hospital from 2017 to 2019 is ideal,but it is still necessary to strengthen the management of the unreasonable use of drugs to be "safe,effective,economical and reasonable".
2020 Vol. 27 (21): 134-138 [Abstract] ( 26 ) HTML (33 KB)  PDF  (0 KB)  ( 10 )
139 Value analysis of urine sediment analyzer combined with urine dry chemistry method for urine white blood cell detection
FU Lian-hua；YU Hai-gen；YE Shan-lan

Objective To explore the value of urine sediment analyzer combined with urine dry chemistry method for urine white blood cell detection. Methods A total of 500 cases of urine specimens from the Third People′s Hospital of Yichun City in Jiangxi Province from January to June 2019 were collected and divided into the control group(n=250)and the observation group (n=250) according to the randomized double-blind method.Urine dry chemical method was used in the control group,and urine sediment analyzer combined with urine dry chemical method was used in the observation group.Urine sediment microscopic examination was used as gold standard,the positive rate,missed diagnosis rate and misdiagnosis rate of urine leucocytes were compared between the two groups.Results The results of urine sediment microscopy showed that the urine leukocyte positive rate of the control group was 79.20% (198/250)，and the urine leukocyte positive rate of the observation group was 77.60%(194/250).There was no significant difference in the positive rate of urine leukocytes between the two groups (P＞0.05).The positive rate of urine leucocytes detected by the test method in the observation group was 76.00% (190/250),which was higher than that in the control group (56.00%) (140/250),and the difference was statistically significant (P＜0.05).The coincidence rate of urine white blood cells detected in the urine samples of the observation group was higher than that of the control group,and the missed diagnosis rate and misdiagnosis rate in the urine samples of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion Urine sediment analyzer combined with urine dry chemistry method can reduce the missed diagnosis rate and misdiagnosis rate of urine leukocyte detection,and improve the detection value.
2020 Vol. 27 (21): 139-141 [Abstract] ( 34 ) HTML (34 KB)  PDF  (0 KB)  ( 9 )
142 Analysis of detection results of coagulation function and related factors in patients with ectopic pregnancy
ZHOU Hai-jun； LIAO Li-jun； LI Hong-mei
Objective To analyze the detection results of coagulation function indexes and related factors in patients with ectopic pregnancy. Methods A total of 50 cases of ectopic pregnancy admitted to our hospital from October 2017 to March 2019 were selected as the observation group,and 50 cases of intrauterine pregnancy who came to our hospital for normal labor examination at the same time were selected as the control group.The levels of endometrial stripe thickness (EST),coagulation function index,human chorionic gonadotropin (β-HCG) and progesterone (P) were compared between the two groups. Results The level of EST in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).The level of fibrinogen (FIB) in the observation group was lower than that in the control group,the activated partial thromboplastin time (APTT),prothrombin time (PT) and thrombin time (TT) in the observation group were longer than those in the control group,the differences were statistically significant (P＜0.05).The levels of β-HCG and P in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).Conclusion There are obvious changes in coagulation function indexes of ectopic pregnancy patients,and there are significant differences in β-HCG,P levels and normal intrauterine pregnancy,clinical diagnosis can be assisted by the detection of these indicators.
2020 Vol. 27 (21): 142-144 [Abstract] ( 35 ) HTML (32 KB)  PDF  (0 KB)  ( 8 )
145 Value analysis of liquid culture and solid culture in the detection of Ureaplasma urealyticum and Mycoplasma hominis in urogenital tract
GUO Dong-yue
Objective To compare and analyze the value of liquid culture and solid culture in detecting Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) in urogenital tract. Methods A total of 854 cases of Mycoplasma in genitourinary tract in our hospital from January to September 2018 were selected.Liquid culture method and solid culture method (gold standard) were used at the same time.The positive detection rate and sample contamination rate of the two methods were observed and compared. Results The positive rate of liquid culture was higher than that of solid culture (43.09% vs.38.41%,P＜0.05).The sensitivity,specificity,positive predictive value and negative predictive value of liquid culture for Uu were 100.00%,94.62%,89.97% and 100.00%,respectively.The sensitivity,specificity,positive predictive value and negative predictive value of liquid culture for Mh were 100.00%,98.88%,84.75% and 100.00%,respectively.The contamination rate of liquid culture was higher than that of solid culture (8.43% vs.1.47%,P＜0.05).Conclusion Liquid culture method has high sensitivity,but it has a certain false-positive rate and pollution rate,so it is suitable for primary screening.
2020 Vol. 27 (21): 145-147 [Abstract] ( 28 ) HTML (33 KB)  PDF  (0 KB)  ( 5 )
148 Application value of serum anti-M-type phospholipase A2 receptor antibody and urine IgG4 detection in the diagnosis of idiopathic membranous nephropathy
CHEN Zhao-sheng
Objective To investigate the application value of serum anti-M-type phospholipase A2 receptor (PLA2R)antibody and urine IgG4 detection in the diagnosis of idiopathic membranous nephropathy. Methods From March 2016 to April 2019,86 patients with membranous nephropathy in our hospital were selected,and 52 cases of idiopathic membranous nephropathy found by renal biopsy were included in the idiopathic group,34 cases of secondary membranous nephropathy were included in the secondary group.The venous blood and mid-range urine samples were collected from two groups of patients for detecting serum PLA2R antibody and urine IgG4 indicators.The positive rate of serum anti PLA2R antibody was compared between the two groups,and the specificity,sensitivity and accuracy were analyzed.At the same time,the results of urine IgG4 of the two groups were compared and ROC curve was analyzed. Results The positive rate of serum anti-PLA2R antibody detection in the idiopathic group (90.38%) was higher than that in the secondary group (5.88%),the difference was statistically significant (P＜0.05).The specificity,sensitivity and accuracy of serum anti PLA2R antibody in the diagnosis of idiopathic membranous nephropathy were 94.12% (32/34),90.38% (47/52) and 91.86% (79/86),respectively.The urinary IgG4 in the idiopathic group was (0.79±0.12) g/L,which was higher than that in the secondary group ([0.52±0.08]g/L),the difference was statistically significant (P＜0.05).The ROC curve showed that the area under the curve of urine IgG4 in the diagnosis of idiopathic membranous nephropathy was 0.856 (detection result ＞0.7),the specificity and sensitivity were 82.70% and 50.00%,respectively.The diagnostic value was relatively ideal.The specificity and sensitivity of serum anti PLA2R antibody in the diagnosis of idiopathic membranous nephropathy were higher than those of urine IgG4,the differences were statistically significant (P＜0.05).Conclusion The positive rate of serum anti PLA2R antibody and urine IgG4 in patients with idiopathic membranous nephropathy are significantly higher than those in patients with secondary membranous nephropathy,which can be used as a reference for clinical diagnosis of idiopathic membranous nephropathy.
2020 Vol. 27 (21): 148-151 [Abstract] ( 31 ) HTML (34 KB)  PDF  (0 KB)  ( 5 )
152 Application effect of pyramid management mode in the nursing management of inpatients with psychosis
CHEN Ze-qun； HUANG Ju-juan；JIANG Jian-mao； CAO Yun-zhen； CHEN Ze-ying；WU Guang-bing4
Objective To discuss the application effect of pyramid management mode in the nursing management of inpatients with psychosis. Methods A total of 90 inpatients with psychosis in Mental Hospital of Guangzhou Civil Affairs Bureau from January to July 2019 were selected,and they were divided into two groups according to the random number table method: the observation group and the control group.All 45 patients in the control group were given the routine management mode,and 45 patients in the observation group were given the pyramid management mode.The rehabilitation effect of the two groups was compared by using the brief psychiatric rating scale (BPRS) score.The total nursing satisfaction between the two groups were compared. Results The BPRS score of the two groups after intervention was lower than that before intervention,the observation group was lower than the control group,and the differences were statistically significant (P<0.05).The total nursing satisfaction of the observation group was higher than that of the control group,and the differences were statistically significant (P<0.05).Conclusion The pyramid management mode can achieve good clinical effect in the inpatients with mental illness,effectively promote the condition of inpatients with mental illness,reduce the BPRS score,and improve the nursing satisfaction of patients′ families,which has high clinical application value.
2020 Vol. 27 (21): 152-154转158 [Abstract] ( 36 ) HTML (34 KB)  PDF  (0 KB)  ( 6 )
155 Application effect of "quality control circle" activity in pharmaceutical care of outpatient western pharmacy
CHE Feng-lian； YI Yan-tao； PAN Min； TAN Cai-hong
Objective To explore the application effect of "quality control circle" in pharmaceutical care in outpatient western pharmacy. Methods From October 2016 to September 2019,24 medical and nursing personnel and their management in outpatient western pharmacy of our hospital were selected as the study objects,who were divided into the control group and the observation group according to different time,12 of which were included in each group.The control group was given routine pharmaceutical care mode,and the observation group applied "quality control circle" activities to compare the implementation effect,total satisfaction,work achievement score of medical staff and the total incidence of error events. Results The implementation effect,tatal satisfaction and work achievement score of the observation group were higher than those of the control group,and the total incidence of error events was lower than that of the control group (P<0.05).Conclusion The implementation of "quality control circle" in outpatient western pharmacy has a good effect,which can effectively improve the satisfaction of pharmaceutical care,improve the working level and ability of pharmacy staff,obtain better work results,and reduce the incidence of error events.
2020 Vol. 27 (21): 155-158 [Abstract] ( 31 ) HTML (1 KB)  PDF  (0 KB)  ( 10 )
159 Study on the application of three-level tracking management method in improving the management level of nursing adverse events
LI Zhi-min
Objective To explore the effect of three-level tracking management method in the management of nursing adverse events. Methods The clinical data of hospitalized patients before (January to December 2017) and after (January to December 2018) the three-level tracking management method method were retrospectively analyzed.They were included in the control group (n=279) and the observation group (n=232) respectively.The occurrence and reporting of adverse nursing events between the two groups were compared. Results The total incidence of adverse nursing events in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).The standardized reporting rate of nursing adverse events in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion The three-level tracking management method can effectively reduce the incidence of nursing adverse events,and effectively improve the standardized reporting rate of nursing adverse events,which is worthy of promotion.
2020 Vol. 27 (21): 159-161 [Abstract] ( 36 ) HTML (31 KB)  PDF  (0 KB)  ( 8 )
162 Application effect of the system of "three sessions and one lesson" in hospital party construction
CAO Qian
Objective To study the application and effect of the "three sessions and one lesson" system in hospital party building. Methods Before January-December 2018 as the "three sessions and one lesson",the party building work followed the conventional method;after January-December 2019 as the "three sessions and one lesson",the party construction work attaches importanced to the "three sessions and one lesson".The application of the system evaluated the number of monthly inspections,monthly notifications,monthly rectifications,theoretical assessment scores,practical assessment scores,and department member management satisfaction rates during the party building process of the hospital before and after the "three sessions and one lesson". Results The number of monthly inspections,monthly notifications,and monthly rectifications in the party building process after the "three sessions and one lesson" were higher than those before the "three sessions and one lesson",and the differences were statistically significant (P<0.05).The scores of the cadres on the theoretical and practical evaluations of the Constitution of the Communist Party of China were higher than those before the "three sessions and one lesson",the differences were statistically significant (P<0.05);after "three sessions and one lesson",the department members had a higher satisfaction rate with the hospital management than before the "three sessions and one lesson",the difference was statistically significant (P<0.05).Conclusion Emphasizing the implementation of the "three sessions and one lesson" system in the development of the hospital′s party building can improve the quality of the party building work,help the majority of party members and cadres to master the party constitution and rules,be stricter with themselves,and promote the continuous improvement of hospital management.
2020 Vol. 27 (21): 162-164转169 [Abstract] ( 24 ) HTML (33 KB)  PDF  (0 KB)  ( 7 )
165 Discussion on promoting the construction of hospital pharmacy window team based on the concept of balanced scorecard
YANG Shi-chun； OU Ru-fen； HUANG Xiao-qu； ZHONG Wei； HUANG Chun-hua
Based on the concept of balanced scorecard,combined with hospital goals,from the four dimensions of finance,process,patient satisfaction and learning growth,14 second-level indicators,23 third-level indicators,performance evaluation of hospital pharmacy window staff is conducted to promote pharmacy window team construction.This article analyzes the current status of hospital pharmacies and finds that there are problems in the management of hospital pharmacies,such as low efficiency of communication between doctors and patients,unreasonable punishment,errors in drug preparation,uneven quality of drugs,and the absence of pharmacy systems.Based on the concept of balanced scorecard,the construction of the window team in the hospital pharmacy can effectively improve the efficiency of the pharmacy window,improve the satisfaction of patients,and effectively improve the overall quality of the window team.
2020 Vol. 27 (21): 165-169 [Abstract] ( 23 ) HTML (42 KB)  PDF  (0 KB)  ( 7 )
170 Application value of problem-based learning teaching model in airway management training for the intensive care unit residents
HE Wei-qun； PAN Jie-yi ；LIU Xiao-qing； SANG Ling； LIANG Wei-bo； NONG Ling-bo
Objective To explore the application value of problem-based learning (PBL) teaching model in the training of airway management for residents in intensive care unit. Methods A total of 100 residents in Intensive Care Unit of Guangzhou Institute of Respiratory Health,the First Affiliated Hospital of Guangzhou Medical University from January 2017 to December 2018 were selected as subjects.They were divided into the control group (n=50) and the observation group (n=50) according to the random number table method.The control group adopted traditional teaching model,and the observation group carried out PBL teaching.After six months of teaching,the teaching quality was evaluated,and the theoretical score,airway management skills score,total training satisfaction,and the total incidence of airway complications were compared between the two groups. Results The theoretical score and airway management skills score in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).The total training satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05).The total incidence of airway complications during airway management in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion For residents in intensive care unit,the use of PBL teaching model in the training of airway management is conducive to improving their airway management skills and the satisfaction of training methods is high,which is helpful to reduce the incidence of airway complications and improve the quality of airway management,which is worthy of promotion and application.
2020 Vol. 27 (21): 170-172转176 [Abstract] ( 29 ) HTML (36 KB)  PDF  (0 KB)  ( 7 )
173 Discussion on the education of the prevention of medical disputes in the standardized training of resident doctors
ZHU Wa-li； CHEN Yi-fei
The education model for the standardized training of resident doctors in China is in the initial exploration stage.The goal of the training is to cultivate clinicians who have good professional ethics,solid medical theory,professional knowledge and clinical skills and can independently undertake the diagnosis and treatment of common diseases in the discipline for medical institutions at all levels.Nowadays,high-quality medical resources are insufficient and unevenly distributed,and medical disputes occur from time to time.In the past,the education of medical students often only focuses on the cultivation of professional knowledge and clinical skills,ignoring the cultivation of humanistic education and doctor-patient communication skills.According to the requirements of standardized training for resident doctors in the new situation,this article discusses how to strengthen the training of resident doctors participating in standardized training in humanities education,policies and regulations,and the doctor-patient communication skills.
2020 Vol. 27 (21): 173-176 [Abstract] ( 27 ) HTML (33 KB)  PDF  (0 KB)  ( 6 )
177 Effect of standardized patient application in the scenario simulation teaching of adverse nursing events
HAN Xiao-ying； CHEN Chun-hua
Objective To explore the effect of standardized patient application in the scenario simulation teaching of adverse nursing events. Methods A total of 297 nurses in our hospital from January 1,2017 to December 31,2018 were selected as research subjects.Before the implementation of scenario simulation teaching (from January to December 2017)was selected as the control group,after the scenario simulation teaching (from January to December 2018) was selected as the observation group.Participants in the control group took the traditional PPT group teaching model,and in the observation group,standardized patient application in the scenario simulation teaching of adverse nursing events was added on the basis of the control group.The scenario simulation teaching,the scores of nurses′ precaution awareness,hazards awareness,causes analyzing ability of adverse events and their mastery degree of preventive measures,the incidence and grade of adverse nursing events were compared between the two groups. Results The scores of nurses′precaution awareness,hazards awareness,causes analyzing ability of adverse events and their mastery degree of preventive measures in the observation group were all higher than those of the control group,and the differences were statistically significant (P＜0.05).The total incidence of adverse nursing events in the observation group was lower than that of the control group,and the difference was statistically significant (P＜0.05).The proportion of adverse events less than or equal to grade Ⅱin the observation group was higher than that of the control group,the difference was statistically significant (P＜0.05).Conclusion Standardized patient application in the scenario simulation teaching of adverse nursing events can increase the assessment score of nurses′ nursing safety programs and reduce the incidence of adverse nursing events,which is worthy of clinical promotion.
2020 Vol. 27 (21): 177-179 [Abstract] ( 30 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
180 Application of case analysis learning model in the cultivation of clinical thinking ability of obstetrics and gynecology for medical students
LI Tian； QIAO Juan； LIU Ying-wei
In order to train qualified clinicians,medical students not only need to learn basic theoretical knowledge,but also be trained how to analyze and solve problems,which is a foundation for clinical entry in the future.Gynecology and obstetrics is a very theoretical and practical subject.In clinical medical education,due to the particularity of the teaching site of obstetrics and gynecology,out of the protection for patients and the awareness of patients′ own protection,to avoid the risk of injury to patients caused by practical mistakes,students have limited opportunities to actual contact patients.The case analysis learning model solves the problem of disconnection between theory and practice,and helps medical students to get rid of the problems of passivity,one-sidedness,dependence and so on.Through clinical case,medical students can learn medical history collection,doctor-patient communication,diagnosis and differential diagnosis,clinical operation and so on.That is a good way for students because the basic theory knowledge is gradually transformed into clinical practical skills which enrich the form of teaching and assessment,and it is helpful to cultivate the clinical thinking ability of medical students in gynecology and obstetrics.This article analyzes the problems existing in the cultivation of the medical students′ clinical thinking ability in gynecology and obstetrics,and shares the experience in the application of case analysis learning model which may be helpful for seeking the effective cultivation methods to improve the clinical teaching effect of obstetrics and gynecology.
2020 Vol. 27 (21): 180-182 [Abstract] ( 37 ) HTML (30 KB)  PDF  (0 KB)  ( 6 )
183 One case of urinary tract infection reported with nodules in the urinary system
YANG Ti； LU Man； DONG Jing； YAO Jia-chen； LIU Yan-hui； LI Wen-yan
The diagnosis and treatment process of 1 case of urinary nodules with urinary tract infection was retrospectively analyzed,and the clinical pharmacist give play to their professional expertise in experiential anti-infective therapy and rational selection of targeted therapeutic drugs for patients,and assist clinicians in formulating and timely adjusting anti-infective drug treatment plan,aiming at promoting clinical individualized drug use,improving drug treatment effect,and ensuring drug safety of patients.
2020 Vol. 27 (21): 183-185 [Abstract] ( 27 ) HTML (31 KB)  PDF  (0 KB)  ( 8 )
186 A case of skull base invagination misdiagnosed as nasopharyngeal carcinoma
RUAN Qing-rong； GU Li-ming； WANG Fu-ping
Skull base invagination is a common malformation in the craniocervical region.It refers to the bone tissue of skull base surrounding the occipital foramen invaginated into the cranial cavity,leading to stenosis of occipital foramen,causing brainstem,medulla oblongata and cervical spinal cord,cerebellum,cranial nerve and peripheral blood vessels to be compressed,and then clinical manifestation will appear.Currently,its pathogenesis has not been clarified,but abnormal embryonic development is mostly considered.There are many types of classifications.It can be divided into primary disease and secondary disease according to the etiology.The disease has a trait of long incubation period and strong concealment.There may be no obvious symptoms at the initial stage of the disease.With the increase of age,the clinical symptoms occur after the bone structure changes.The clinical manifestations are mainly nerve compression symptoms,and characteristic appearance can be accompanied.Currently,the diagnosis mainly depends on imaging findings such as plain radiographs,CT and magnetic resonance imaging (MRI).For patients with suspected skull base invagination,MRI should be preferred.If the patient does not have obvious clinical symptoms,conservative treatment and regular follow-up visits are necessary.However,when clinical symptoms occur,surgery must be performed as soon as possible to alleviate the compression.In this paper,we shared a case of misdiagnosis with dysphagia as the first symptom.Through a retrospective study of recent years′ knowledge related to skull base invagination,this misdiagnosis is analyzed and discussed to deepen the understanding of the skull base invagination and improve clinical vigilance.Hopefully early diagnosis and early treatment of the disease can be achieved.
2020 Vol. 27 (21): 186-188转194 [Abstract] ( 33 ) HTML (34 KB)  PDF  (0 KB)  ( 7 )
189 One case of severe arrhythmia caused by Paclitaxel in ovarian cancer patient
WANG Xiu-xiu； YANG Bing
Paclitaxel is an antitumor drug with unique structure and mechanism of action.Paclitaxel combined with Platinum is the first-choice chemotherapy for ovarian cancer treatment.Cardiotoxicity of Paclitaxel is rare,but there are reports that the drug can cause a series of cardiac changes such as asymptomatic eletrocardiogram abnormalities,blood pressure changes,arrhythmias,myocarditis,pericarditis,tamponade,acute myocardial infarction,heart failure,shock,chronic cardiomyopathy,etc,which reduce heart function of patients,thus affecting curative effect,reducing the quality of life,and these changes may occur during medication or several years after medication.Therefore,it is of great significance in tumor therapy to discover the cardiotoxicity of Paclitaxel as early as possible and take effective measures to reduce the occurrence of cardiac complications.The mechanism and treatment scheme of Paclitaxel-induced arrhythmia were analyzed and discussed through a case of arrhythmia in ovarian cancer patient after Paclitaxel administration.
2020 Vol. 27 (21): 189-194 [Abstract] ( 38 ) HTML (39 KB)  PDF  (0 KB)  ( 7 )
195 Application effect of psychological nursing in the nursing of oncology department
LI Jian-xia；DAI Xiao-qing
Objective To explore the application effect of psychological nursing in the nursing of oncology department.Methods A total of 60 cancer patients admitted to our hospital from June 2018 to June 2019 were selected as the research objects,and they were divided into the control group (n=30) and the observation group (n=30) by the random number table method.The control group was given routine nursing,and patients in the observation group were given psychological nursing on the basis of the control group.The anxiety and depression scores before and after nursing and the total satisfaction degree were compared between the two groups. Results There was no significant difference between the two groups in the scores of anxiety and depression before nursing (P＞0.05).The scores of anxiety and depression in the two groups after nursing were lower than those before nursing,with statistical differences (P<0.05).The scores of anxiety and depression in the observation group after nursing were (13.37±3.93) and (21.23±3.62) points,lower than those in the control group of (19.27±3.89) and (37.86±4.57) points,with statistical differences (P<0.05).The total satisfaction in the observation group was 96.67%,which was higher than 73.33% in the control group,the difference was statistically significant (χ2=4.7114,P<0.05).Conclusion In the nursing of department of oncology,psychological nursing can significantly improve patients′ anxiety and depression,and improve patients′ satisfaction,which is worthy of clinical promotion.
2020 Vol. 27 (21): 195-197 [Abstract] ( 34 ) HTML (32 KB)  PDF  (0 KB)  ( 10 )
198 Application of improved walker in rapid rehabilitation nursing of esophageal cancer
WU Yi-fan； FU Dan； CAO Hong-yan； FANG Zheng
Objective To explore the application value of improved walker in the rapid rehabilitation nursing of esophageal cancer. Methods A total of 60 postoperative patients who underwent esophageal cancer surgery in our hospital from January 2018 to May 2019 were selected as study subjects.They were divided into observation group and control group according to the random principle,30 cases in each group.The control group used ordinary walkers,the observation group used modified walkers,the various indicators of the two groups of patients were compared. Results The first time to get out of bed in the observation group was shorter than that in the control group,and the duration of the first time to get out of bed was longer than that in the control group,with statistical differences (P<0.05).The drainage tube removal time and hospital stay in the observation group were shorter than those in the control group,with statistical differences (P<0.05);the incidence of pulmonary infection and detubation in the observation group were lower than those in the control group,the total satisfaction in the observation group was 100.00%,the total satisfaction in the observation group was higher than that of the control group (80.00%),with statistical differences (P<0.05).Conclusion The improved walker used in the rapid rehabilitation nursing of esophageal cancer after surgery can promote patients to get out of bed actively and promote postoperative rehabilitation,which is worthy of clinical application.
2020 Vol. 27 (21): 198-200 [Abstract] ( 29 ) HTML (33 KB)  PDF  (0 KB)  ( 8 )
201 Application effect of nursing on the five excessive emotions in the external counterpulsation treatment of patients with sleep disorders after ischemic stroke
LIU Mu-jun； LI Zhen-nan； CHEN Dan
Objective To explore the application effect of nursing on the five excessive emotions in the external counterpulsation treatment of patients with sleep disorder (SD) after ischemic stroke (CIS).Methods Totally 120 patients with SD after CIS treated in our hospital from July 2018 to June 2019 were selected as research subjects.They were divided into control group (n=60) and study group (n=60) by randomly drawing lots.The two groups were both treated with external counterpulsation.Meanwhile,the patients in the control group were treated with conventional nursing,and the patients in the study group were provided with the five excessive emotions nursing.The Pittsburgh sleep quality index (PSQI) factors and total scores,and the score of healthy SF-36 scale(Chinese version)were compared between the two groups before and after nursing. Results The sleep duration score,sleep latency score,daytime function score,sleep quality score,sleep efficiency score,sleep disorder score,and total score between the two groups had no significant differences (P＞0.05).After nursing,the score of sleep duration in the study group was (5.15±0.45) points,which was higher than that of the control group of (3.93±0.65) points,the difference was statistically significant (P<0.05).After nursing,the sleep latency score,day function score,sleep quality score,sleep efficiency score,sleep disorder score and total score in the study group were (1.15±0.33),(6.75±0.60),(1.55±0.25),(0.60±0.25),(0.85±0.20)and(15.85±0.65)points,respectively,lower than those of the control group of (1.45±0.41),(7.95±0.40),(1.95±0.60),(1.05±0.50),(1.37±0.55) and(17.85±1.54) points,respectively,the differences were statistically significant (P<0.05).The overall health score,physiological function score,physiological role score,physical pain score,vitality score,social function score,emotional role score,and mental health score in the two groups before nursing had no significant differences (P＞0.05).After treatment,the overall health score,physiological function score,physiological role score,physical pain score,vitality score,social function score,emotional role score,and mental health score in the study group were (74.65±12.30),(72.65±13.50),(66.75±10.45),(69.85±11.50),(80.65±14.50),(81.65±14.30),(90.35±12.50) and (76.85±13.50) points,respectively,higher than those of the control group of (62.45±10.01),(66.35±10.30),(58.45±8.70),(63.95±10.50),(71.70±12.30),(74.65±12.40),(77.75±13.50) and (66.35±12.50) points,respectively with statistical differences (P<0.05).Conclusion Implementing nursing on the five excessive emotions combined with external counterpulsation on patients with SD after CIS can effectively improve their PSQI factors,PSQI total score and quality of life score.
2020 Vol. 27 (21): 201-204 [Abstract] ( 40 ) HTML (34 KB)  PDF  (0 KB)  ( 7 )
205 Application effect of comprehensive nursing on patients with hemodialysis
WANG Shao-lan
Objective To explore the application effect of comprehensive nursing on patients with hemodialysis (HD).Methods A total of 100 HD patients treated in our hospital from September 2018 to September 2019 were selected as research subjects.They were divided into observation group (n=50) and control group (n=50) by random number table method.Conventional nursing was adopted in the control group,and comprehensive nursing was used in the observation group.The self-care ability score,compliance and quality of life of the two groups were compared. Results The scores of self-care ability such as HD knowledge,attitude towards HD and self-care skills in the observation group were higher than that of the control group,and the differences were statistically significant (P<0.05).The compliance and quality of life scores of patients in the observation group were higher than those of the control group,and the differences were statistically significant (P<0.05).Conclusion For patients receiving HD,comprehensive nursing can better improve their self-care ability compared with the conventional nursing,and it also can improve their medication compliance and quality of life,which is worthy of promotion and application.
2020 Vol. 27 (21): 205-207 [Abstract] ( 41 ) HTML (31 KB)  PDF  (0 KB)  ( 8 )
208 Application effect of psychological nursing intervention in patients with chronic obstructive pulmonary disease and respiratory failure
PENG Qing-mei； ZHANG Xue-yu； PENG Mei-lian； HUANG Hui-zhao
Objective To explore the application effect of psychological nursing intervention in patients with chronic obstructive pulmonary disease (COPD) with respiratory failure. Methods A total of 86 patients with COPD and respiratory failure who were hospitalized in our hospital from October 2018 to September 2019 were selected as the research subjects.They were divided into the control group (n=43) and the observation group (n=43) according to coin tossing method.The control group performed routine nursing,the observation group performed routine nursing combined with psychological nursing,the two groups of patients with psychological anxiety,depression and nursing satisfaction before and after nursing were compared. Results The psychological anxiety and depression of the observation group were lower than those in the control group,and the nursing total satisfaction was higher than that in the control group,the differences were statistically significant (P<0.05).Conclusion Psychological nursing intervention can effectively improve the psychological anxiety and depression of patients with COPD and respiratory failure,and improve the patient′s nursing satisfaction.It has significant application value.
2020 Vol. 27 (21): 208-210转214 [Abstract] ( 31 ) HTML (33 KB)  PDF  (0 KB)  ( 9 )
211 Application effect of Bo′s abdominal acupuncture combined with psychobehavior nursing on patients with maintenance hemodialysis
ZHOU Zhen-li；ZHU Li-fang；FENG Liu-chang； WEI Li-liang；TAN Qin-xiang
Objective To explore the application effect of Bo′s abdominal acupuncture combined with psycho-behavior nursing on patients with maintenance hemodialysis (MHD).Methods A Total of 68 MHD patients admitted to our hospital from August 2017 to August 2019 were selected as research subjects.They were divided into observation group(n=34) and control group (n=34) by random allocation.Patients in the observation group were received with Bo′s abdominal acupuncture combined with psycho-behavior nursing intervention,and in the control group was treated with traditional body acupuncture.The clinical efficacy,sleep quality,and quality of life (physical function,emotional activity,social function,and mental state) were compared between the two groups. Results The total clinical effective rate in the observation group was 94.1%,higher than that of the control group,accounting for 62.0%,the difference was statistically significant (P<0.05).The sleep quality score in the observation group was lower than that of the control group,and the difference was statistically significant (P<0.05).The quality of life score in the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion In the course of clinical treatment,Bo′s abdominal acupuncture combined with psycho-behavior nursing has a good therapeutic effect on patients with MHD and can improve their quality of life.
2020 Vol. 27 (21): 211-214 [Abstract] ( 34 ) HTML (36 KB)  PDF  (0 KB)  ( 8 )
215 Effect of strengthening nursing during operation on swelling and pain of knee joint after total knee arthroplasty
FENG Yin-zhen； HUANG Su-zhen； YU Jian-hua； YANG Zhi-dong； LI Liu-yi
Objective To investigate the effect of strengthening nursing intervention during operation on swelling and pain of knee joint after total knee arthroplasty (TKA).Methods A total of 72 patients undergoing TKA who were treated in our hospital from January to December 2018 were selected as the research objects.They were divided into study group (n=36) and control group (n=36) according to the random number table method.The control group was given routine nursing intervention,the study group was given strengthening nursing intervention during operation on the basis of routine nursing.The postoperative knee joint swelling and pain of the two groups were compared. Results The degree of swelling of the knee joint in the study group was lighter than those in the control group (P<0.05);the visual analogue scale (VAS) scores of the study on the 1st,3rd,and 5th day after the operation group were lower than those of the control group,which was statistically significant (P<0.05).The quality of life scores of patients in the study group were higher than those in the control group after surgery,with statistically significant difference (P<0.05).Conclusion Streagthening nursing interventions during operation for patients undergoing TKA can effectively reduce the degree of swelling of the knee joint,reduce pain,significantly improve the quality of life of patients,and thus increase patient satisfaction.
2020 Vol. 27 (21): 215-217 [Abstract] ( 33 ) HTML (32 KB)  PDF  (0 KB)  ( 9 )
218 Application of perioperative nursing in patients with lumbar disc herniation undergoing percutaneous endoscope
ZHU Yan-ling
Objective To investigate the application of perioperative nursing in patients undergoing percutaneous foraminal lumbar disc herniation. Methods A total of 80 patients with lumbar disc herniation who were treated in our hospital from July 2015 to March 2018 were selected as research objects.They were divided into control group (n=40)and an observation group (n=40) according to dynamic randomization method.The control group adopted routine nursing,and the observation group adopted perioperative nursing intervention.The quality of life scores,visual analogue scale (VAS) scores,total postoperative care satisfaction of the two groups were compared. Results Before nursing,there were no significant differences in the quality of life and VAS scores between the two groups (P＞0.05).After nursing,the quality of life score in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05),the VAS score was lower than that of the control group,and the difference was statistically significant (P<0.05).The total satisfaction of nursing in the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion PTED for patients with lumbar disc herniation has obvious perioperative nursing effect,good safety performance,and is worthy of promotion.It also provides a more reliable reference value for future research.
2020 Vol. 27 (21): 218-220转224 [Abstract] ( 39 ) HTML (33 KB)  PDF  (0 KB)  ( 8 )
221 Application effect of targeted nursing intervention in mydriasis before cataract surgery
WU Yu-ping； LIU Hong
Objective To explore the application effect of targeted nursing intervention in mydriasis before cataract surgery. Methods The clinical data of 200 cases of cataract patients treated by phacoemulsification combined with intraocular lens implantation in our hospital from November 2018 to June 2019 were retrospectively analyzed.According to different nursing methods,they were divided into control group (n=100) and experimental group (n=100).The control group used routine nursing method,the experimental group used the targeted nursing method based on routine nursing.The effect of mydriasis,levels of intraoperative pupil diameter,nursing satisfaction and incidence of adverse reactions were compared between the two groups. Results There was no significant difference in pupil diameter before mydriasis between the two groups (P＞0.05).The pupil diameter (after 30 minutes of mydriasis and before implantation),nursing total satisfaction of the experimental group were higher than those of the control group,the levels of intraoperative pupil diameter was better than that of the control group,the total incidence of adverse reactions of the experimental group was lower than that of the control group,the differences were statistically significant (P<0.05).Conclusion Targeted nursing intervention for patients who need cataract surgery can improve the effect of mydriasis,improve the nursing satisfaction of patients and reduce the incidence of adverse reactions.
2020 Vol. 27 (21): 221-224 [Abstract] ( 35 ) HTML (34 KB)  PDF  (0 KB)  ( 8 )
225 Application of cluster nursing in prevention of lower extremity deep vein thrombosis
LUO Li-dan； LIN Yue-feng； XIAO Dan
Objective To explore the application of cluster nursing in the prevention of lower extremity deep vein thrombosis (LDVT).Methods From January to October 2019,98 patients who were admitted to our hospital for ″major orthopaedic surgery″ (hip replacement,knee replacement,hip fracture surgery and internal fixation of femoral neck and intertrochanteric fractures) were selected as the observation group,and the patients were given cluster nursing and routine nursing,98 patients were treated with″ major orthopaedic surgery″ from January to December 2018 as the control group (routine nursing).The incidence of LDVT,the awareness rate of patients′ health knowledge,the satisfaction rate of patients′ nursing and the qualified rate of LDVT prevention were compared between the two groups. Results The incidence of LDVT in the observation group was lower than that in the control group (P<0.05).The awareness rate of health knowledge in the observation group was higher than that in the control group (P<0.05).The nursing satisfaction and the qualified rate of LDVT prevention in the observation group were higher than those in the control group,the differenced were statistically significant (P<0.05).Conclusion The application of cluster nursing in LDVT prevention,combined with clinical nursing pathway,can effectively improve the implementation of nursing staff in LDVT prevention,reduce the incidence of LDVT,improve the patients′ nursing satisfaction and nursing quality,which has positive economic and social benefits，and is worthy of clinical promotion.
2020 Vol. 27 (21): 225-227 [Abstract] ( 36 ) HTML (31 KB)  PDF  (0 KB)  ( 7 )
228 Application of knowledge attitude belief practice mode in cholecystectomy patients
PAN Jie； LIU Si-si； WANG Kang-li
Objective To explore the application value of knowledge attitude belief practice (KABP) mode in patients with cholecystectomy. Methods Sixty patients with gallstone,cholecystitis treated in our hospital from January 2017 to January 2019 were selected as the research subjects,and they were divided into the control group (n=30) and the observation group (n=30) according to the different nursing methods.In the control group,the traditional nursing service mode was used.In the observation group,KABP nursing mode was applied.The time of bowel sound recovery after surgery,the time to get exhausted after surgery,the time to recover from defecation after surgery,the time to take food after surgery,visual analogue scale (VAS) score,and self-rating anxiety scale (SAS) score,and self-depression rating scale (SDS) score,Pittsburgh sleep quality index (PSQI) score,and scores of abdominal distension and nausea and vomiting before and 10 days after nursing intervention were compared between two groups. Results The time bowel sound recovery after surgery,the time to get exhausted after surgery,the time to recover from defecation after surgery,the time to take food after surgery in the observation group were shorter than those of the control group,the differences were statistically significant (P<0.05).The VAS,SAS,SDS,and PSQI scores were lower in the observation group than that in the control group with statistical differences (P<0.05).The scores of abdominal distension and nausea and vomiting 10 days after intervention were higher than those before intervention,the scores of abdominal distension and nausea and vomiting 10 days after intervention were lower in the observation than those in the control group,with statistical differences (P<0.05).Conclusion The use of KABP nursing service mode for patients performed with cholecystectomy shows favorable nursing effect,which helps patients recover as soon as possible after surgery,alleviate their pain,improve their anxiety and depression,and sleep quality,and relieve abdominal distension and nausea and vomiting.
2020 Vol. 27 (21): 228-230 [Abstract] ( 34 ) HTML (30 KB)  PDF  (0 KB)  ( 7 )
231 Application of continuous rehabilitation nursing in postoperative rehabilitation of patients with soft tissue injury
CHEN Lian-di；QU Jie-song； HUANG Ping-yan；YANG Jun-gui；YANG Shuai-zhi；LI Hui-fang
Objective To investigate the effect of continuous rehabilitation nursing on the recovery of hand function after treatment of arterial venous flap in patients with soft tissue injury. Methods A retrospective analysis of 60 patients with arterial venous flaps who were discharged from our hospital from March 2017 to December 2018 was performed to repair patients with soft tissue defects.The patients were divided into observations group (n=30) and control group(n=30) according to different nursing methods.Both groups of patients were treated according to the rehabilitation nursing path of arterial venous flaps for repairing soft tissue injury of the hand during hospitalization.Patients in the control group underwent routine discharge care,follow-up and rehabilitation guidance one week later,and patients in the observation group were given continuous rehabilitation care on the basis of the control group.The hands of sensory function,motor function recovery of the two groups were compared at 1,3,and 6 months after surgery. Results There was no significant difference in hand motor function and sensory function between the two groups at 1 month after operation (P＞0.05).The total excellent and good rate of hand movement in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05).The S5 grade of sensory function in the observation group was higher than that of the control group at 3 and 6 months after operation,the difference was statistically significant (P<0.05).Conclusion Continuous rehabilitation nursing for patients with arterial venous flap repairing hand soft tissue injury can promote the recovery of hand movement function and sensory function and shorten the recovery time of patients.
2020 Vol. 27 (21): 231-234 [Abstract] ( 32 ) HTML (34 KB)  PDF  (0 KB)  ( 5 )
235 Application effect of comfort nursing in perianal nursing after anorectal surgery
HOU Miao； SHAN Shu-zhen
Objective To explore the application effect of comfort nursing in perianal nursing after anorectal surgery.Methods The clinical data of 118 patients undergoing anorectal surgeries treated in our hospital from January 2018 to June 2019 were retrospectively analyzed.They were divided into the control group and the study group according to different nursing models,59 cases in each group.In the control group was adopted conventional nursing,and in the study group comfort nursing was used.The pain degrees at different time points,sleep quality before and after nursing,and changes in mental state 48 h after surgery were compared. Results The pain scores of patients in the study group at 4,12,24,and 48 h after surgery were lower than those in the control group (P＜0.05).The pain scores at 12,24,and 48 h after surgery in the two groups were all lower than 4 hours after surgery (P＜0.05).Meanwhile,the Pitsburgh sleep quality index questionnaire (PSQI) and 90 item self-rating scale for mental symptoms (SCL-90) score of the study group after nursing were also lower compared with that in the control group ((P＜0.05)).The PSQI and SCL-90 score in the two groups after nursing were lower than those before nursing (P＜0.05).Conclusion Comfort nursing has obvious advantages in perianal care after anorectal surgery.It can effectively relieve pain,and improve postoperative psychological status and sleep quality.
2020 Vol. 27 (21): 235-237 [Abstract] ( 33 ) HTML (31 KB)  PDF  (0 KB)  ( 8 )
238 Application of clinical nursing pathway in patients undergoing laparoscopic radical rectal cancer surgery
LI Chao-qun
Objective To explore the appliction effect of clinical nursing pathway in laparoscopic rectal cancer patients.Methods A retrospective analysis was made on 104 patients who underwent laparoscopic rectal cancer radical operation from January 2016 to January 2019.According to different nursing plans,they were divided into control group (n=52) and study group (n=52).The control group adopted routine nursing mode,and the study group adopted clinical nursing path mode.The total incidence of complications,recovery time and subjective nursing satisfaction were compared between the two groups. Results ①The total incidence of complications in the study group was lower than that in the control group,and the difference was statistically significant (P<0.05).②Rehabilitation time (anal exhaust time,bed time,hospitalization time) in the study group were shorter than those in the control group,the differences were statistically significant (P<0.05).③The excellent rate of subjective nursing experience in the study group was higher than that in the control group,and the difference was statistically significant (P<0.05).Conclusion The application of clinical nursing pathway in laparoscopic radical resection of rectal cancer has a good effect,which can help to reduce the complications of operation,promote the recovery of patients,and improve their subjective nursing experience,which is clinical reference.
2020 Vol. 27 (21): 238-240 [Abstract] ( 36 ) HTML (30 KB)  PDF  (0 KB)  ( 6 )
241 Application of multidisciplinary cooperative team led by nurses in continuous nursing of gastrointestinal cancer patients
JIANG Ye； KUANG Xue-chun
Objective To explore the application effect of multi-disciplinary team （MDT） cooperation led by nurses in continuous nursing of gastrointestinal cancer patients. Methods From January 2018 to July 2019,120 patients with gastrointestinal cancer in our hospital were selected as the study objects.The patients were divided into intervention group (n=60) and control group (n=60) by random number table method.The patients in the two groups were given routine nursing and discharge guidance.Routine follow-up was performed in the control group.The continuous nursing with MDT cooperation led by nurses was carried out in the intervention group.The self-care ability and the burden level were compared between the two groups. Results At admission,there was no significant difference in self-care ability between the two groups (P＞0.05).Three months after discharge,the self-care ability scores of the two groups were higher than those at admission (P<0.05).Three months after discharge,the self-care ability score of the intervention group was higher than that of the control group (P<0.05).At admission,there was no significant difference in burden score between the two groups (P＞0.05).Three months after discharge,the burden of caregivers scores in the two groups were lower than those at admission (P<0.05).Three months after discharge,the burden of caregivers score in the intervention group was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion The continuous nursing of MDT cooperation led by nurses can improve the self-care ability of gastrointestinal cancer patients and reduce the care burden of caregivers.
2020 Vol. 27 (21): 241-244 [Abstract] ( 41 ) HTML (35 KB)  PDF  (0 KB)  ( 6 )
245 Application effect of clinical nursing rehabilitation pathway in rehabilitation of adult patients with large area burns
LIU Yan； LIU Jun-jun； WANG Yu-ying； TANG Yuan-yan
Objective To observe the application effect of clinical nursing rehabilitation pathway in rehabilitation of adult patients with large area burns. Methods A total of 90 adult patients with extensive burn which admitted to our hospital from October 2017 to December 2018 were selected and divided into two groups according to random number table method,45 cases in each group.The control group received routine nursing intervention,and the observation group received clinical nursing rehabilitation intervention.The hospital stay time and hospital expenses of the two groups were compared,and the health knowledge,treatment satisfaction,burn wound scar status and post-intervention quality of life of the two groups were compared.The negative emotional changes of the two groups before and after intervention were compared. Results There was no significant difference in body image score between the two groups after intervention (P＞0.05),but the other quality of life scores in the observation group were higher than those in the control group,the differences were statistically significant (P<0.05).The hospital stay in the observation group was shorter than that in the control group,the hospitalization cost was less than that in the control group,the vancouver scar scale (VSS) score was lower than that in the control group,and the satisfaction and health knowledge awareness scores were higher than those in the control group,the differences were statistically significant (P<0.05).There was no significant difference in Hamilton anxiety scale (HAMA) score between the two groups before intervention (P＞0.05).There was no significant difference in the comparison of the control group before and after the intervention (P>0.05).The scores of the HAMA factors in the observation group were lower than those of before the intervention and the control group,the difference were statistically significant (P<0.05).Conclusion The clinical nursing rehabilitation pathway can significantly improve the satisfaction and health knowledge of adult patients with large area burns,significantly improve wound scar,quality of life and negative emotions,shorten the length of hospitalization and reduce the cost of hospitalization.
2020 Vol. 27 (21): 245-248 [Abstract] ( 36 ) HTML (38 KB)  PDF  (0 KB)  ( 4 )
249 Application of Chinese medicine nursing program in patients with colorectal polyps
LEI Song-hua
Objective To explore the application of Chinese medicine nursing program in colorectal polyps,and to provide reference for further improvement of the program. Methods A total of 116 patients with the first diagnosis of colorectal polyps admitted to our hospital from July 2018 to July 2019 were selected as study subjects.According to the random lottery method,they were divided into the control group and the observation group,58 cases in each group.The control group was given routine nursing,and the observation group was given the intervention of Chinese medicine nursing program on the basis of routine nursing.The psychological status,healing effect and total satisfaction of the two groups were compared. Results After nursing,the scores of the self-rating anxiety scale (SAS) and the self-rating depression scale (SDS) of the observation group were lower than those of the control group,and the differences were statistically significant（P<0.05）.The Chinese medicine symptom score,disease efficacy score and middle (distal) efficacy score of the observation group were higher than those of the control group,and the differences were statistically significant (P<0.05).The total nursing satisfaction of the observers was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion The effect of intervention on Chinese medicine nursing program in patients with colorectal polyps is significant,which can effectively improve the psychological state of patients,improve the curative effect of patients,improve patients satisfaction,and has certain clinical application value.
2020 Vol. 27 (21): 249-252 [Abstract] ( 39 ) HTML (35 KB)  PDF  (0 KB)  ( 7 )
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