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2019 Vol. 26, No. 17
Published: 2019-06-18
4
Effect of Dexmedetomidine on postoperative recovery quality and early cognitive function in patients with microvascular decompression
CAI Bo-tao; TANG Ji-wei; LI Yong; ZHANG Bai-yin
Objective
To investigate the effect of Dexmedetomidine on postoperative recovery quality and early cognitive function in patients with microvascular decompression.
Methods
Sixty patients who underwent elective microvascular decompression in our hospital from January 2017 to June 2018 were enrolled in the study.They were divided into Dexmedetomidine group(group D)and control group(group C)according to the random number table method,30 cases in each group.The group D was given Dexmedetomidine before induction of anesthesia,and the group C was injected with normal saline by the same method.The general conditions of surgery(operation time,blood loss,urine volume,infusion volume of crystal and colloidal)were compared between the two groups.The hemodynamic parameters(systolic blood pressure,heart rate)were observed in the two groups at the following points,such as resting into the room for 5 min (T
1
),anesthesia-induced intubation(T
2
),surgical incision(T
3
),drilling of the skull(T
4
),vascular decompression(T
5
),and end of operation(T
6
).The postoperative respiratory recovery time,waking time,extuba-tion time and coughing score and agitation score during extubation were recorded in the two groups.The serum levels of interleukin-6(IL-6),tumor necrosis factor-α (TNF-α)and plasma cortisol(COR)were measured at 1 day before operation(t
1
),at the completion of operation(t
2
)and 24 hours after operation(t
3
).The neurological function test by Wechsler adult intelligence scale(WAIS),Wechsler memory scale(WMS)and mini-mental state examination(MMSE)was performed to evaluate the cognitive function at t
1
and 3 days after operation.The incidence rate of postoperative cognitive dysfunction(POCD)was compared between the two groups.
Results
There were no significant differences in the operation time,blood loss,urine volume,crystal and colloidal infusion volume between the two groups(P＞0.05).The systolic blood pressure at T
2
,T
4
and T
5
in the group D was significantly lower than that in group C,the heart rate at T
2
and T
4
was significantly lower than that in the group C,and the differences were statistically significant(P＜0.05).There were no significant differences in the postoperative respiratory recovery time,waking time and extubation time between the two groups (P＞0.05).The conditions of cough and agitation in the group D were better than those in the group C during the extubation,and the differences were statistically significant(P＜0.05).There were no significant differences in serum levels of IL-6,TNF-α and COR between the two groups at t
1
(P＞0.05).The serum levels of IL-6,TNF-α and COR at t
2
and t
3
in the two groups were higher than those at t
1
,and the differences were statistically significant(P＜0.05).The serum levels of IL-6,TNF-α and COR at t
2
and t
3
in the group D were higher than those in the group C,and the differences were statistically significant(P＜0.05).The scores of MMSE,visual regeneration and word association at in the group D were significantly higher than those in the group C at 3 days after operation,the digital symbol time and connection time were significantly shorter than those in the group C,and the differences were statistically significant(P＜0.05).The incidence rate of POCD in the group D was significantly lower than that in the group C,and the difference was statistically significant(P＜0.05).
Conclusion
The application of Dexmedetomidine in patients with microvascular decompression can maintain stable perioperative hemodynamic indexes,improve the recovery quality and reduce the incidence of POCD.The mechanism may be related to reducing stress and inflammatory reaction.
2019 Vol. 26 (17): 4-8 [
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64
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9
Effect of Compound Flumetasone on the expression of Th17 cell associated cytokines in patients with advanced vulgaris psoriasis
HUANG Mei-xing； ZHU Lu； FENG Lei； LEI Shui-sheng
Objective
To investigate the effect of Compound Flumetasone in the treatment of psoriasis on the expression of helper T (Th17)cell associated cytokines.
Methods
A total of 52 patients with psoriasis who were admitted to the Dermatology Clinic of the Fifth Affiliated Hospital of Guangzhou Medical University from January 2016 to June 2018 were selected as the research group,and 52 healthy people who underwent the physical examination were randomly selected as the control group.The venous blood of the research group was collected before treatment(T
1
),1 week after treatment(T
2
),and 4 weeks after treatment(T
3
),and the venous blood collection time of the control group was the time of the physical examination(T
4
).The serum levels of interleukin-17A(IL-17A),interleukin-17F(IL-17F),interleukin-17E/25(IL-17E/-25),interleukin-6(IL-6)and tumor necrosis factor-α (TNF-α)were detected.The treatment effect of patients in the research group was evaluated according to the psoriasis area and severity index (PASI)score.
Results
The serum levels of Th17 cell associated cytokines at T
3
in the research group were lower than those at T
2
and T1,T
2
was lower than T
1
,and the differences were statistically significant(P＜0.05).The serum levels of Th17 cell associated cytokines at T
1
and T
2
in the research group were higher than those in the control group,and the differences were statistically significant(P＜0.05).There were no significant differences in serum levels of Th17 cell associated cytokines between the research group at T
3
and the control group (P＞0.05).The total effective rate of treatment at T
2
in the research group was 76.92%,and the total effective rate of treatment at T
3
in the research group was 92.31%.The total effective rate of treatment at T
3
in the research group was higher than that at T
2
,and the difference was statistically significant(P＜0.05).
Conclusion
Compound Flumetasone has a good therapeutic effect on patients with advanced vulgaris psoriasis,it can significantly reduce the PASI score and the expression of Th17 cell associated cytokines in the body of patients,which is worthy of clinical promotion.
2019 Vol. 26 (17): 9-11转25 [
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] (
76
)
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12
Application of acute ischemic stroke by “one-stop”multi-modality CT
WANG Jin-ding； WAN Shan-shan； ZHANG Ji-lin； YANG Chun-jing； WAN He-bin
Objective
The perfusion imaging of"one-stop"multi-modality CT can reflect the abnormal perfusion of cerebral tissue in patients with cerebral infarction,while the CT cerebral angiography can clarify the vascular stenosis or occlusion in head and neck.In this paper,to discussed the value of"one-stop"multi-modal CT in the diagnosis of acute ischemic stroke.
Methods
A total of 96 patients with acute ischemic stroke within 4.5 to 24 h and admitted to the department of neurology in our hospital from June 2015 to December 2017 were selected as subjects.All participants were confirmed by magnetic resonance-diffusion-weighted imaging (MRI-DWI),but did not receive intravenous thrombolysis or embolectomy.The patients were examined by the"one-stop"multi-modal CT scan of the brain.The parameters of CT perfusion imaging(CTP)were observed and compared,and the relationship between the vascular stenosis and cerebral perfusion abnormality was analyzed by CT perfusion and vascular software.
Results
①MRI was taken as the gold standard for acute ischemic stroke.The accuracy of NCCT scan was 39.6%,and the accuracy of multimodal CT was 93.8%.②For 90 patients with abnormal CTP perfusion,there were 38 cases with the ischemic penumbra.Both in the infarct core area and the ischemic penumbra,they had lower values of cerebral blood flow (CBF)in cerebral infarction side than in the contralateral mirrored area,the mean transit time (MTT)and time to peak (TTP)values were longer than the values in the contralateral mirrored area,the cerebral blood volume (CBV)in the infarct core area was significantly lower than that in the infarct mirror area,the differences were statistically significant(P＜0.05).However,for other 52 patients without the ischemic penumbra,values of all parameters except for CBV in cerebral infarction side were significantly different from the values in the contralateral mirrored area (P＜0.05).③CTA could effectively evaluate the degree and location of arterial stenosis,there was a relationship between the abnormal perfusion area and the degree of arterial stenosis(P＜0.05).
Conclusion
The “one stop” multi-modal CT examination of the brain is simple and rapid.It can demonstrate the hemodynamic changes and the morphology of the vessels in ACI patients,which is conducive to the early diagnosis of acute cerebral infarction,and is more conducive to individualized therapy.
2019 Vol. 26 (17): 12-16 [
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] (
76
)
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17
Research progress of medical treatment of advanced primary liver cancer
ZHANG Qing； SHEN Yong-qi； HAN Chao-wen； CHEN Chao-ting
Primary liver cancer(PLC)is one of the most common malignant tumors with the highest mortality.Most of the patients are diagnosed at advanced stages.Medical treatment is the main treatment for middle and advanced stage patients.In recent years,the combination of biological targeting therapy and chemotherapy has become a hot topic in cancer clinical research.Biologically-targeted therapy and chemotherapy are commonly used in the internal medicine treatment of malignant tumor.In recent years,the combination of biologically-targeted therapy and chemotherapy in the treatment of tumor has become a hot spot in the clinical research of tumor.This article reviews the biological targeting therapy and chemotherapy in the medical treatment of middle and advanced stage PLC.
2019 Vol. 26 (17): 17-20 [
Abstract
] (
77
)
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21
Research progress of short-term and long-term respiratory outcomes in premature infants with bronchopulmonary dysplasia
LIU Gui-ping
Bronchopulmonary dysplasia(BPD)is a chronic respiratory disease associated with preterm birth,primarily affecting preterm infants<29 weeks of gestational age.With the development of perinatal technology,the survival rate of premature infants is significantly increased,but with the increase in the number of children with BPD.Given the increasing number of children with BPD,it is necessary to raise awareness of short-and long-term respiratory diseases in children with BPD.In this paper,the published related literatures are reviewed and summarized.According to different age stages,the current research progress on the prognosis of BPD respiratory system is summarized from infants to preschool,from school age to adolescence.In order to pay more attention to and emphasize the individualized follow-up plan in clinical work,it manages and treats short-term and long-term respiratory diseases of children with BPD according to different age stages.
2019 Vol. 26 (17): 21-25 [
Abstract
] (
79
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26
Clinical effect of percutaneous pedicle screw fixation surgery in the treatment of thoracolumbar spine fracture
XIONG Guang
Objective
To explore the effect of percutaneous pedicle screw fixation surgery in the treatment of thoracolumbar spine fracture.
Methods
A total of 62 patients with the new diagnosis of thoracolumbar spine fractures in our hospital from January to December 2016 were selected as the study subjects.They were divided into observation group and control group according to the random number table method,with 31 cases in each group.Patients in the observation group received percutaneous pedicle screw fixation surgery,and those in the control group underwent open pedicle screw fixation.The injury vertebrae height ratio and Cobb angle at different times were observed in the two groups.The operation time,intraoperative blood loss,length of incision and indwelling time of the drainage tube were compared between the two groups.
Results
There was no significant difference in the injury vertebrae height ratio between the two groups before the operation and at the 7
th
day and 3
rd
month follow-up(P＞0.05).The injury vertebrae height ratio at the 7
th
day and 3
rd
month follow-up in the two groups was significantly higher than that before the operation,and the difference was statistically significant(P＜0.05).There was no significant difference in the Cobb angle between the two groups before the operation and at the 7
th
day and 3
rd
month follow-up (P＞0.05).The Cobb angle at the 7
th
day and 3
rd
month follow-up in the two groups was significantly lower than that before the operation,and the difference was statistically significant(P＜0.05).The operation time,incision length and indwelling time of the drainage tube in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(P＜0.05).The intraoperative blood loss of the observation group was significantly less than that of the control group,and the difference was statistically significant(P＜0.05).
Conclusion
The effect of open pedicle screw fixation and percutaneous pedicle screw fixation surgery is similar in the treatment of thoracolumbar spine fracture,but the latter is more minimally invasive.
2019 Vol. 26 (17): 26-29 [
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] (
90
)
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30
Application of superficial vein of the carpal volar volar in complex replantation of severed fingers
LI Zhi； LIU Long-ling； FANG Hong； Ni Shao-jun； YANG Jun
Objective
To explore the application of superficial vein of the carpal volar volar in complex replantation of severed fingers.
Methods
A total of 19 patients with complicated severed finger replantation and disconnection admitted to our hospital from August 2013 to May 2018 were selected as subjects,the blood supply was reconstructed by superficial volar vein transplantation,after thorough debridement,the length of the isolated arterial defect was about 1.2-1.8 cm and the average defect was(1.50±0.12)cm,the prognosis of the patients was observed.
Results
In this study,19 patients were treated with superficial vein grafting to reconstruct the blood supply,and all the fingers were alive,no arteriovenous crisis occurred after operation,the follow-up period was 1 to 6 months,the appearance of the affected finger was good after repair,and the excellent and good rate was 94.7%.
Conclusion
The diameter of the superficial vein of the carpal volar volar is consistent with the finger artery,which is suitable for complex severed finger replantation.
2019 Vol. 26 (17): 30-32 [
Abstract
] (
70
)
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33
Effect comparison of Pemetrexed+Cisplatin and Docetaxel+Tegiol in the treatment of advanced breast cancer
LIU Yan-cui； ZHAO Wei； SUN Ping ； SUN Cheng
Objective
To compare the effect of Pemetrexed+Cisplatin and Docetaxel+Tegiol in the treatment of advanced breast cancer.
Methods
All of 80 patients with breast cancer admitted to our hospital from March 2015 to July 2017 who met the inclusion criteria were retrospectively analyzed.The patients were divided into the Pemetrexed group(n=40)and Docetaxel group (n=40)according to the random number table method.Pemetrexed group was treated with Pemetrexed+Cisplatin,while Docetaxel group was treated with Docetaxel+Tegiol.The short-term efficacy,KPS score and adverse reactions in patients of the two groups were analyzed.
Results
Compared with before treatment,the KPS scores of both groups increased after treatment,and the differences were statistically significant(P＜0.05).There was no significant difference in KPS score between the two groups after treatment(P＞0.05).There were no significant differences in ORR and DCR between the two groups (P＞0.05).The main adverse reactions of the two groups were bone marrow suppression and gastrointestinal tract reaction,which could be alleviated after symptomatic supportive treatment.There were no significant differences in bone marrow suppression,gastrointestinal reaction,alopecia and rash classification between the two groups(Z=1.91,2.62,1.85,3.02,P＞0.05).
Conclusion
The clinical effect and safety of Pemetrexed+Cisplatin and Docetaxel+Tegiol in the treatment of advanced breast cancer have little difference.It can be selected according to the condition of breast cancer patients.
2019 Vol. 26 (17): 33-35 [
Abstract
] (
90
)
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36
Effect of retroperitoneal laparoscopic partial nephrectomy in the treatment of localized renal cell carcinoma
YU Zhao-cun； HUANG Hua-sheng； YANG Chang-jun； FANG Zhong-jin； CHEN Zao-qing
Objective
To investigate the effect of retroperitoneal laparoscopic partial nephrectomy in the treatment of localized renal cell carcinoma.
Methods
Eighty patients with localized renal cell carcinoma admitted to our hospital from March 2015 to October 2018 were selected as study objects.They were divided into the experimental group(n=40)and control group (n=40)according to the random grouping method.The experimental group was given retroperitoneal laparoscopic partial nephrectomy,while the control group was given open renal partial resection.The operation time,hospital stay,total hospitalization cost,total incidence of postoperative complications and various renal function indicators were compared in partients between the two groups.
Results
The hospital stay of the experimental group was shorter than that of the control group,the total hospitalization cost was lower than that of the control group,with statistical significances(P＜0.05).The total incidence of postoperative complications in the experimental group was lower than that of the control group,with a significant difference (P＜0.05).There were no significant differences in various renal function indicators between the two groups (P＞0.05).
Conclusion
Retroperitoneal laparoscopic partial nephrectomy in the treatment of localized renal cell carcinoma has the advantages of quick recovery,good curative effect and low cost,and little impact on renal function,which can be used in clinical treatment.
2019 Vol. 26 (17): 36-38 [
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] (
81
)
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39
Application effect of cervical fascial space plane separation in thyroid carcinoma surgery
WU Guo-hai； DENG Jiang-bo； ZHANG Ming-wen
Objective
To explore the application value of the method of cervical fascial space separation in thyroid cancer surgery.
Methods
From January 2010 to December 2017,40 patients with thyroid cancer were selected as control group,and 40 patients with thyroid carcinoma from January 2018 to January 2019 were selected as observation group.The control group received the traditional surgical treatment,and the observation group used a surgical treatment plan for the separation of the cervical fascia gap.The therapeutic effects after treatment were compared between the two groups.
Results
The operative time of the patients in the observation group was longer than that in the control group,the amount of intraoperative bleeding was less than that in the control group,and the number of dissected lymph nodes was more than that in the control group,and the differences were statistically significant(P＜0.05).The incidence of superior laryngeal nerve injury and recurrent laryngeal nerve injury and the recurrence rate in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).
Conclusion
The method of cervical fascial space separation as a new surgical method for thyroid cancer not only improves the treatment effect of surgery,but also reduces the incidence of postoperative complications and recurrence rate,and has a good clinical application value.
2019 Vol. 26 (17): 39-41 [
Abstract
] (
71
)
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42
Effect of transcatheter arterial chemoembolization on peripheral circulation tumor cells and vascular endothelial growth factor in primary liver cancer
QIU Ze-cheng； CHEN Bin； LI Liu-sheng； CHEN Jian-jian； WANG Shi-jia； HUANG Xiong-pei； LIN Yan-feng
Objective
To investigate the effect of transcatheter arterial chemoembolization on peripheral circulating tumor cells and vascular endothelial growth factor in primary liver cancer.
Methods
A total of 200 patients with primary liver cancer admitted to our hospital from May 2016 to September 2018 were selected as the study subjects and randomly divided into observation group and control group,100 cases in each group.The control group was treated with conventional western medicine,while the observation group was treated with transcatheter arterial chemoembolization.The positive rate of peripheral circulating tumor cells,the number of peripheral circulating tumor cells and the level of vascular endothelial growth factor were compared between the two groups before and after treatment.
Results
Before treatment,there was no significant difference in the positive rate of peripheral circulation tumor cells between the two groups (P＞0.05).After treatment,the positive rate of peripheral circulation tumor cells in the observation group was lower than that in the control group,the difference was significant(P＜0.05).Before treatment,there were no significant difference in the number of peripheral circulation tumor cells and the level of vascular endothelial growth factor between the two groups(P＞0.05).After treatment,the number of peripheral circulation tumor cells and the level of vascular endothelial growth factor in the observation group were lower than those in the control group,the differences were significant(P＜0.05).
Conclusion
Transcatheter arterial chemoembolization is of high clinical value in the treatment of primary liver cancer,which can reduce the number of peripheral circulation tumor cells and the level of vascular endothelial growth factor.
2019 Vol. 26 (17): 42-44 [
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] (
69
)
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45
Appilcation value of color Doppler ultrasonography and mammography in the screening of breast cancer
LAI Sheng-lan
Objective
To explore the value of color Doppler ultrasound combined with molybdenum target in breast cancer screening.
Methods
A total of 400 female patients who underwent breast cancer examination in our hospital from January 2017 to April 2018 were selected as research objects,all patients with color Doppler ultrasound and mammary gland molybdenum target for diagnosis,the detection rates of the two diagnostic Methods applied alone and in combination were compared.
Results
The detection rate of the color Doppler ultrasound group alone was 5.75%(23/400),which was not statistically significant compared with the mammography group alone(5.50%[22/400])(P＞0.05).The detection rate of the two diagnostic Methods combined group[9.75%(39/400)]was higher than that of the color Doppler ultrasound group alone,and the difference was statistically significant(P＜0.05).The detection rate of the two diagnostic Methods combined group was higher than that of the mammography group alone,and the difference was statistically significant(P＜0.05).
Conclusion
In the clinical diagnosis of breast cancer patients,the combination of color Doppler ultrasound and mammography can significantly improve the diagnostic detection rate,and has a higher clinical value in the early diagnosis of breast cancer patients.
2019 Vol. 26 (17): 45-47 [
Abstract
] (
76
)
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48
Effect of simultaneous removal of one-stage tumors and hyperplastic prostates treating superficial bladder cancer with prostatic hyperplasia
LIU Ming-jian； LI Wen-zhao； WU Bao-zhong； XIAO Jian； ZHANG Qi-fei
Objective
To study the effect of simultaneous removal of one-stage tumors and hyperplastic prostates treating superficial bladder cancer with prostatic hyperplasia.
Methods
All of 41 patients superficial bladder cancer with prostatic hyperplasia treated in our hospital from March 2015 to March 2018 were divided into the observation group(n=21)and control group (n=20)by the random number table method.The observation group was given simultaneous removal of one-stage tumors and prostates,while the control group was given simple electrosurgical treatment of bladder tumors.The therapeutic effect was compared between the two groups.
Results
After treatment,the IPSS score of the observation group was lower than that of the control group,the residual urine flow was less than that of the control group,and the maximum urine flow rate was higher than that of the control group (P＜0.05).The recurrence rate of the observation group(4.76%)was significantly lower than that of the control group(30.00%)(P＜0.05).
Conclusion
Simultaneous removal of one-stage tumors and hyperplastic prostates treating superficial bladder cancer with prostatic hyperplasia can relieve the lower urinary tract obstruction and reduce the recurrence rate obviously.
2019 Vol. 26 (17): 48-50 [
Abstract
] (
75
)
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51
Effect of hand-assisted laparoscopic surgery treating colorectal tumors
LIU Hai-rui； LIU Bo； LIANG Guo-dong； CHENG Xian-bin
Objective
To explore the effect of hand-assisted laparoscopic surgery (HALS)treating colorectal tumors.
Methods
Altogether 180 patients who were confirmedly diagnosed with colorectal cancer in our hospital from January 2015 to August 2017,required selective operation and met inclusion criteria were retrospectively analyzed.According to the actual treatment methods,all the patients were divided into the control group(n=100)and observation group(n=80).The control group was given laparoscopic-assisted colorectal surgery(LAC),while the observation group was given HALS.Operative related indexes,therapeutic effect,survival rate and recurrence rate were compared between the two groups.
Results
The operation time of the observation group was significantly shorter than that of the control group,the amount of bleeding was significantly less than that of the control group (P＜0.05).There were no significant differences in the number of injured intestinal wall,ureter and lymph nodes between the two groups (P＞0.05).There were no significant differences in the time of exhaust,the number of pain,the time of getting out of bed,the time of catheterization,the time of liquid food/diet feeding and hospitalization between the two groups(P＞0.05).There were no significant differences of 1 year survival rate and the recurrence rate between the two groups(P＞0.05).
Conclusion
The short-term and long-term effect of HALS in the treatment of colorectal tumors is similar to that of LAC,but HALS is more suitable for clinical application because of its shorter operation time and less intraoperative bleeding.
2019 Vol. 26 (17): 51-53 [
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] (
72
)
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54
Clinical effect of Apatinib in the treatment of advanced non-squamous non-small cell lung cancer
SU Sheng-tian； LIU Jun
Objective
To analyze the clinical effect of Apatinib in the treatment of advanced non-squamous non-small cell lung cancer.
Methods
Fifty patients with advanced non-squamous non-small cell lung cancer admitted to our hospital from December 2015 to February 2018 were selected as the subjects,and divided into control group and experimental group according to the numerical random method,with 25 cases in each group.The control group received conventional chemotherapy,and the experimental group received Apatinib.The total response rate,total adverse reaction rate,hospitalization time,and quality of life scores were compared between the two groups.
Results
The total remission rate of the experimental group was significantly higher than that of the control group,and the difference was statistically significant(P＜0.05).The total adverse reaction rate of the experimental group was significantly lower than that of the control group,and the difference was statistically significant(P＜0.05).The hospitalization time of the experimental group was significantly shorter than that of the group,and the quality of life score was significantly higher than that of the control group,the differences were statistically significant(P＜0.05).
Conclusion
The treatment effect of Apapitatin in patients with advanced non-squamous non-small cell lung cancer is significant.The incidence of adverse reactions is lower and the treatment effect is better.It can improve the quality of life of patients and shorten the length of hospital stay.Patients are more acceptable.It is worth promoting in clinical application.
2019 Vol. 26 (17): 54-56转60 [
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83
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57
Summary of clinical experience in the initial stage of thoracic laparoscopy combined with radical resection of esophageal cancer surgery
YI He-qiang; CHEN Guang-ming; LIU Hao
Objective
To summarize the relevant clinical experience by comparing the intraoperative and postoperative data of thoracic laparoscopy combined with radical resection of esophageal cancer surgery and traditional thoracotomy.
Methods
The clinical data of 69 patients with esophageal cancer admitted to our hospital from May 2017 to May 2018 were retrospectively analyzed.They were divided into minimally invasive group(28 cases)and open group(41 cases)according to different surgical methods.Patients in the minimally invasive group underwent thoracic laparoscopy combined with radical resection of esophageal cancer surgery,and patients in the open group underwent traditional thoracotomy.The intraoperative blood loss,operation time,number of lymph node dissection,volume of postoperative thoracic drainage,removal time of thoracic drainage tube,postoperative hospitalization time and total incidence rate of postoperative pulmonary complications were compared between the two groups.
Results
The operation time in the minimally invasive group was longer than that in the open group,the intraoperative blood loss and postoperative thoracic drainage volume were less than those in the open group,the number of lymph node dissection was more than that in the open group,and the removal time of thoracic drainage tube was shorter than that in the open group,with statistically significant differences(P＜0.05).There was no significant difference in postoperative hospitalization time between the two groups(P＞0.05).The total incidence rate of postoperative pulmonary complications in the minimally invasive group was 31.7%,which was significantly lower than that in the open group(7.1%),and the difference was statistically significant(P＜0.05).
Conclusion
The effect of thoracic laparoscopy combined with radical resection of esophageal cancer surgery is significantly better than that of traditional thoracotomy,which is worthy of widespread promotion.However,the experience of the early stage of radical surgery for minimally invasive esophageal cancer is not rich to operators.
2019 Vol. 26 (17): 57-60 [
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74
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61
Application effects of Pemetrexed combined with Nedaplatin chemotherapy in the treatment of patients with advanced lung adenocarcinoma
YANG Ding-hong ; LIN Chang-yu; HUANG Xiao-long
Objective
To explore the application effects of Pemetrexed combined with Nedaplatin chemotherapy in the treatment of patients with advanced lung adenocarcinoma.
Methods
A total of 60 patients with advanced lung adenocarcinoma treated in department of medical oncology of our hospital from February 2014 to February 2015 were selected as the subjects,and randomly divided into treatment group and control group,with 30 cases in each group.The control group was treated with Gemcitabine combined with Nedaplatin chemotherapy,and the treatment group was given Pemetrexed combined with Nedaplatin chemotherapy.The effective rate of treatment,serum tumor marker levels before and after treatment and occurrence of adverse reactions were compared between the two groups.Patients were given 4 to 24 months of outpatient or telephone follow-up,and the overall survival time was recorded of the two groups.
Results
The total effective rate of treatment in treatment group (63.33%)was higher than that in control group (36.67%)(P＜0.05).The levels of serum carcinoembryonic antigen(CEA),neuron-specific enolase(NSE),carbohydrate antigen 50(CA50)and carbohydrate antigen(CA199)in treatment group were lower than those in control group after treatment(P＜0.05).The incidence rates of alopecia,rash,leukopenia,neutropenia,thrombocytopenia,liver and kidney function damage and nausea and vomiting in treatment group were lower than those in control group (P＜0.05).The overall survival time in treatment group was(18.56±4.67)months,which was longer than that in control group ([14.29±4.72]months)(P＜0.05).
Conclusion
Pemetrexed combined with Nedaplatin chemotherapy has significant efficacy in the treatment of advanced lung adenocarcinoma,and it can effectively improve serum tumor markers levels and prolong survival time.
2019 Vol. 26 (17): 61-64 [
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106
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65
Effect comparison of laparoscopic and open radical resection of cervical cancer combined with abdominal para-aortic lymph node dissection in the treatment of early cervical cancer
QIU Yi
Objective
To compare the clinical effects of laparoscopic and open radical resection of cervical cancer combined with para-aortic lymph node dissection in the treatment of early cervical cancer.
Methods
Ninety patients with early cervical cancer who were admitted to our hospital from December 2013 to December 2015 were selected as the subjects,and divided into the control group and an observation group by random sampling,with 45 cases in each group.The control group was treated with open radical laparoscopic radical resection combined with para-aortic lymph node dissection.The observation group was treated with laparoscopic and para-aortic lymph node dissection.The operation,postoperative complications and survival rate of the two groups were observed,and the treatment effect was compared.
Results
The exhaust time,drainage tube removal time of the observation group were shorter than those of the control group,and intraoperative bleeding volume of the observation group was less than that of the control group,and the differences were statistically significant(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group (P＜0.05).There was no significant difference in 1,2 and 3 years survival rate between the two groups (P＞0.05).
Conclusion
Laparoscopy combined with para-aortic lymph node dissection for the treatment of patients with early cervical cancer is effective,can shorten exhaust time,drainage tube extraction time,and reduce intraoperative blood loss,and postoperative complications are less,and has higher safety.It has clinical application value.
2019 Vol. 26 (17): 65-67 [
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84
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Application effect of kangaroo nursing combined with breast milk fortifier in premature infants
LIU Ning； ZHAN Zhi-yi； LI Rui-chun； JIANG Jian-hua； HU Xiao-cheng
Objective
To explore the application effect of kangaroo nursing combined with breast milk fortifier in premature infants.
Methods
A total of 120 cases of premature infants admitted to our hospital from August 2016 to August 2017 were selected as the research objects.They were divided into group A(40 cases),group B(40 cases)and group C(40 cases)according to the random number table method.Group A used breast milk fortifier alone,Group B used routine nursing measures,Group C used kangaroo care combined with breast milk fortifier.The physical development index,milk intake and complications of three groups of premature infants were compared.
Results
The growth rates of body weight,head circumference and body length of premature infants in group C were higher than those in group A and group B,the differences were statistically significant(P＜0.05).The milk intake of group C was significantly higher than that of group A and group B at 4 weeks of intervention,the differences were statistically significant(P＜0.05).The incidence of feeding intolerance,sepsis and bronchopulmonary dysplasia in group C was significantly lower than that in group A and group B,the differences were statistically significant(P＜0.05).
Conclusion
Kangaroo nursing combined with breast milk fortifier can effectively promote physical development,increase milk intake and reduce complications.
2019 Vol. 26 (17): 68-70转75 [
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73
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71
Clinical effect of hysteroscopic scissors resection in the treatment of endometrial polyp infertility
YU Jing-chun
Objective
To investigate the clinical effect of hysteroscopic scissors resection in the treatment of endometrial polyp infertility.
Methods
A total of 120 cases of patients with endometrial polyp infertility who were treated in our hospital from January 2016 to June 2017 were selected as subjects.According to the random number table method,they were divided into observation group and control group,60 cases in each group.The control group was treated with hysteroscopic curettage and the observation group with hysteroscopic scissors resection.Perioperative indexes(the amount of intraoperative blood loss,operation time,hospital stay)were recorded in both groups.The menstrual blood loss map was used to evaluate the menstrual flow of the two groups before surgery and 1,6 and 12 months after surgery.The enzyme-linked immunosorbent assay was used to determine the levels of serum vascular endothelial growth factor(VEGF)in the two groups.After 12 months of follow-up,the polyp recurrence rate and the success rate of natural pregnancy were compared between the two groups.
Results
Both groups successfully completed the operation,and the success rate of the operation was as high as 100.00%.There were no significant differences in the amount of intraoperative blood loss,operation time and hospital stay between the two groups (P＞0.05).The postoperative recurrence rate in the observation group was 5.00%,which was significantly lower than that in the control group (25.00%),and the success rate of natural pregnancy was 95.00%,which was significantly higher than that in the control group (70.00%),with statistically significant differences(P＜0.05).There was no significant difference in the amount of menstrual flow between the two groups before surgery(P＞0.05).The menstrual volume of the control group at 1 and 6 months after surgery was less than that before surgery,and the difference was statistically significant(P＜0.05).There was no significant difference in the amount of menstrual flow in the control group between the 12 months after surgery and before surgery (P＞0.05).The amount of menstrual flow in the observation group at 1,6,and 12 months after surgery was significantly less than that before surgery and in the control group,and the differences were statistically significant(P＜0.05).There were no significant differences in serum VEGF levels between the two groups before surgery and 1 month after surgery (P＞0.05).At 1,6,and 12 months after surgery,serum VEGF levels in the two groups were significantly lower than those before surgery,and the differences were statistically significant(P＜0.05).The serum VEGF levels in the observation group at 6 and 12 months after surgery were significantly lower than those in the control group,and the differences were statistically significant(P＜0.05).
Conclusion
Compared with hysteroscopic curettage,hysteroscopic scissors resection is more effective in the treatment of endometrial polyp infertility.The postoperative natural pregnancy rate is higher and the recurrence rate is lower.The mechanism may be related to a significant down-regulation of VEGF expression in endometrial tissues.
2019 Vol. 26 (17): 71-75 [
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93
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Effect comparison of different
Methods
to prevent post-adhesion after trans-cervical resection of adhesion
Methods to prevent post-adhesion after trans-cervical resection of adhesion[J]. 中国当代医药, 2019,26(17): 76-78')" href="#">
XIAN Jie-feng； TAN Jie-yin； LIU Hai-ling
Objective
To analyze the effect of different
Methods
to prevent post-adhesion after intrauterine adhesions.
Methods
Ninety patients with severe intrauterine adhesions admitted to our hospital from June 2015 to June 2018 were selected as subjects,and divided into groups A,B and C according to the random number table method,with 30 cases in each group.In all three groups,intrauterine adhesions were performed,and intrauterine device+oral Estradiol Valerate was placed in group A.Group B was placed with chitosan+intrauterine device+oral Estradiol Valerate after surgery.And the Chitosan+COOK balloon stent+oral Estradiol Valerate was placed in group C.Before the operation and 3 months after the operation,hysteroscopy was performed to observe the adhesion and the menstrual status was recorded.
Results
There was no significant difference in the intrauterine adhesion score and menstrual score between the three groups before operation(P＞0.05).The postoperative adhesion score of group B was lower than that of group A(P＜0.05).The intrauterine adhesion score was lower in group than in group B(P＜0.05).The menstrual score of group B was lower than that of group A (P＜0.05).The menstrual score of group C was lower than that of group B (P＜0.05).
Conclusion
The application of COOK balloon combined with Chitosan and oral Estradiol Valerate in patients with intrauterine adhesions can effectively prevent postoperative intrauterine adhesions and improve menstrual status.The clinical effect is significant and worthy of clinical application.
2019 Vol. 26 (17): 76-78 [
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78
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79
Clinical diagnostic value of early pregnancy serology combined with NT screening in Down′s syndrome
LU Mei-huan； ZHANG Li-you； YE Li-hua； WU Zhi-qun
Objective
To analyze the diagnostic effect of serological markers combined with B-ultrasound on the thickness of fetal neck transparent layer(NT)on early pregnant patients with Down syndrome(DS).
Methods
A total of 3376 pregnant women who admitted to our hospital from January 2017 to March 2018 were selected as subjects for this study.Screening for DS in the mother,taking the B-ultrasound to measure the thickness of the fetal NT,and serologically detecting the levels of free human chorionic gonadotropin(β-HCG)and pregnancy-related protein(PAPP-A).To analyze the accuracy of the diagnosis of NT screening methods,serological detection and NT screening Methods combined with serology.
Results
The abnormal rate of high-risk patients obtained by the combined screening method was 7.14%,which was much higher than the abnormal rate of high-risk patients obtained by single screening.And determine the risk of maternal disease with DS through joint screening,and then diagnose the possibility of maternal adverse pregnancy outcomes.
Conclusion
Serological and NT screening Methods are more effective in diagnosing DS than in single screening.It can predict the incidence of maternal adverse pregnancy more scientifically and accurately,and reduce birth defects and improve population quality,which has a good clinical application value and is worth promoting.
2019 Vol. 26 (17): 79-81 [
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] (
83
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82
Application effect of 3%hypertonic saline in children with intracranial hypertension
DAI Ben-qi； LIN Xue； ZHANG Zhi-mei； WU Min； LIN Si-min
Objective
To explore the application effect of 3%hypertonic saline and 20%Mannitol in children with intracranial hypertension.
Methods
The clinical data of 44 children with intracranial hypertension admitted to our hospital from July 2016 to December 2018 were collected and divided into observation group and control group according to the order of admission,22 cases in each group.The observation group was treated with 3%hypertonic saline,while the control group was treated with 20%Mannitol,the rest of the treatment depended on the specific situation.The effect of reducing intracranial pressure,the final effect,serum sodium,osmotic pressure and hospitalization time were compared between the two groups.
Results
There was no significant difference in intracranial pressure between the two groups before treatment(P>0.05).The intracranial pressure level of the two groups after treatment were lower than those before treatment,the differences were statistically significant(P<0.05).The level of intracranial pressure in the observation group after treatment was lower than that in the control group,the difference was statistically significant(P<0.05).The total effective rate of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).There was no significant difference in serum sodium and osmotic pressure between the two groups before treatment(P>0.05).After 3 days of treatment,the level of serum sodium in the control group was lower than that before treatment,and the level of plasma osmotic pressure was higher than that before treatment,the differences were statistically significant(P<0.05).The levels of serum sodium and plasma osmotic pressure in the observation group were higher than those before treatment and in the control group,the differences were statistically significant(P<0.05).There was no significant difference in hospitalization time between the two groups(P>0.05).
Conclusion
3%hypertonic saline is superior to 20%mannitol in lowering intracranial pressure in children with intracranial hypertension,and does not reduce serum sodium concentration and osmotic pressure,which is worthy of clinical application.
2019 Vol. 26 (17): 82-85 [
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] (
88
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86
Analysis of serum vitamin A and E levels in pregnant women during different pregnancy periods
ZHAN Ying-jie； YANG Xiu-ru； FENG Gui-ling； LIU Jin-zhi
Objective
To analyze the detection
Results
of serum vitamin A and E levels in pregnant women at different gestational stages.
Methods
All of 856 women of different gestational stages received in outpatient department of our hospital from July 2015 to April 2017 were selected as the study objects.They were divided into the early pregnancy group(n=236),mid-pregnancy group(n=309),late pregnancy group(n=311)according to different gestational stages.Serum vitamin A and E levels were detected in all three groups,and the results were analyzed and compared.
Results
The serum vitamin A level in early pregnancy group was lower than that in mid-pregnancy group (P＜0.05),there was no difference between early pregnancy group and late pregnancy group (P＞0.05),the serum vitamin A level in late pregnancy group was lower than that in mid-pregnancy group (P＜0.05).The serum vitamin E level in early pregnancy group was lower than that in mid-pregnancy group (P＜0.05),the serum vitamin E level in early pregnancy group was lower than that in late pregnancy group (P＜0.05),and the serum vitamin E level in late pregnancy group was higher than that in mid-pregnancy group (P＜0.05).The abnormal rate of serum vitamin A level in early pregnancy group was not different from that in mid-pregnancy group(P＞0.05),the abnormal rate of serum vitamin A level in early pregnancy group was different from that in late pregnancy group (P＜0.05),and the abnormal rate of serum vitamin A level in late pregnancy group was higher than that in mid-pregnancy group(P＜0.05).The abnormal rate of serum vitamin E level in the early pregnancy group was different from that in the middle and late pregnancy group (P＜0.05),and the abnormal rate of serum vitamin E level in the late pregnancy group was different from that in the mid-pregnancy group(P＜0.05).The abnormal rate of serum vitamin E level in late pregnancy group was higher than that in early and mid-pregnancy group (P＜0.05).
Conclusion
Serum vitamin A and E levels of pregnant women in different gestational stages are different.With the increase of gestational weeks,vitamin A is deficient,and vitamin E is excessive.In order to effectively guarantee the safety of pregnant women and fetuses,it is necessary to strengthen clinical testing and timely and reasonable supplementation.
2019 Vol. 26 (17): 86-88 [
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68
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Effect of Leonurus Heterophyllus Injection combined with Oxytocin on prevention of postpartum hemorrhage after cesarean section
LIU Yao-yao
Objective
To study the effect of Leonurus Heterophyllus Injection combined with Oxytocin on prevention of postpartum hemorrhage after cesarean section.
Methods
Altogether 90 cases of women who underwent cesarean section and admitted to our hospital from June 2017 to August 2018 were selected as the objects,and divided into observation group and control group according to the computer random method,with 45 cases in each group.The observation group was given Leonurus Heterophyllus Injection combined with Oxytocin prevention,the control group was given Oxytocin prevention.The therapeutic effect,bleeding volume at different time,uterine fundus height and adverse reactions of the two groups were compared.
Results
The total effective rate of women undergoing cesarean section in the observation group was higher than that in the control group (P＜0.05).The amount of bleeding during operation,2 hours and 24 hours after operation in the observation group were less than those in the control group,with statistically significant difference (P＜0.05).The uterine fundus height of the observation group were lower than those of the control group at 3 and 5 days after cesarean section (P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group (P＜0.05).
Conclusion
Leonurus Heterophyllus Injection combined with Oxytocin has a very significant clinical effect and high safety in prevention of postpartum hemorrhage after cesarean section,which is worth studying.
2019 Vol. 26 (17): 89-91 [
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57
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92
Relationship between serum markers of Down′s syndrome screening and pathological pregnancy in the second trimester of pregnancy
GUO Fang-fang
Objective
To investigate the relationship between serum markers of Down′s syndrome screening and pathological pregnancy in the second trimester of pregnancy.
Methods
Altogether 873 pregnant women who were treated in Daxing District Maternal and Child Health Hospital of Beijing City from January 2016 to December 2018 were selected as the subjects.The upper quartile of alpha-fetoprotein (AFP)and human chorionic gonadotropin (β-hCG)levels of pregnant women included in the study was taken as the cut-off point,based on which all the patients were divided into the elevated group and the normal group.The lower quartile of the free estriol(uE3)concentration of pregnant women included in the study was taken as the cut-off point,based on which the patients were divided into the lowered group and the normal group.The incidence of pathological pregnancy was compared among pregnant women in different AFP,β-hCG and uE3 groups.
Results
Of all the pregnant women,123 cases had elevated AFP and 750 cases had normal AFP.The incidence of pathological pregnancy in the elevated AFP group was higher than that in the normal AFP group(P＜0.05).Of all the pregnant women,147 cases had elevated β-hCG and 726 cases had normal β-hCG.The incidence of pathological pregnancy in the elevated AFP group was higher than that in the normal AFP group(P＜0.05).Of all the pregnant women,267 cases had decreased uE3 and 606 cases had normal uE3.The incidence of pathological pregnancy in the lowered uE3 reduction group was higher than that of normal uE3 group (P＜0.05).
Conclusion
The serum markers of AFP,β-hCG and uE3 in Down′s screening for the second trimester of pregnancy has certain guiding significance for pathological pregnancy.
2019 Vol. 26 (17): 92-94 [
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61
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Clinical study of Glucocorticoid in the treatment of Mycoplasma pneumoniae lobar pneumonia in children
CHEN Yuan-ge
Objective
To investigate the effect of Glucocorticoid adjuvant therapy on Mycoplasma pneumoniae lobar pneumonia in children.
Methods
A total of 40 cases of children with Mycoplasma pneumoniae lobar pneumonia admitted to our hospital from July to October 2018 were selected as research objects.The patients were divided into control group and observation group by random touching method,20 cases in each group.The control group was received conventional treatment respectively.The observation group was received Glucocorticoid treatment on top of conventional basic treatment.Clinical observation indexes,adverse reactions and pulmonary function improvement were compared between the two groups.
Results
The fever abatement time,cough relief time,moist rale disappearance time,X-ray recovery time and hospitalization time of the patients in the observation group were shorter than those in the control group,the differences were statistically significant(P＜0.05）;the overall incidence of adverse reactions such as facial flushing,abdominal pain,heart rate acceleration,rash and the control group had no significant difference(P＞0.05）.The first second forced respiratory volame(FEV
1
),forced vital capacity(FVC),peak expiratory flow(PEF)of the patients in the two groups before treatment had no significant difference(P＞0.05）.FEV
1
,FVC and PEF in the observation group were significantly higher than those in the control group after treatment(P＜0.05）.
Conclusion
Glucocorticoid adjuvant therapy for children with Mycoplasma pneumoniae lobar pneumonia can improve the clinical efficacy of patients with high application value.
2019 Vol. 26 (17): 95-97 [
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49
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Clinical application effect of arterial embolization in gynecological refractory diseases
CAI Hao-ran； LU Shao-hong； YANG Jin-qiong
Objective
To evaluate the clinical application effect of arterial embolization in gynecological refractory diseases.
Methods
The clinical data of 42 patients with gynecological refractory benign and malignant tumors admitted to our hospital from January 2013 to October 2018 were retrospectively analyzed.According to different treatment methods,they were divided into study group(21 cases)and control group(21 cases).Patients in the study group were treated with arterial embolization,and patients in the control group were treated with conventional methods.The menstrual volume,dysmenorrhea,uterine volume,CA125 level,hemostasis time and the incidence of complications were compared between the two groups.
Results
Patients in the study group were superior to those in the control group in terms of decreased menstrual volume,uterine volume reduction,decreased dysmenorrhea score,decreased CA125 level and hemostasis time,with statistically significant differences(P＜0.05).The total incidence rate of complications in the study group was 19.0%,which was significantly lower than that in the control group (66.7%),and the difference was statistically significant(P＜0.05).
Conclusion
The arterial embolization provides a safe and effective treatment option for gynecologic refractory benign and malignant diseases.
2019 Vol. 26 (17): 98-101转104 [
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59
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Implementation of free position during labor process and its effect on delivery
LUO Lian-hua
Objective
To study the application value of free position during labor process.
Methods
A total of 180 parturient women who received treatment in our hospital from April 2017 to January 2019 were selected and computer randomized double blind method was used to divide the experimental group and the control group,90 cases in each group.The experimental group was adopted the free position method during childbirth,and the control group was adopted the traditional supine position.The parturient effect of the two groups was analyzed,and the parturient duration and other indicators of two groups were compared.
Results
The rate of spontaneous delivery was 88.89%,higher than that of control group (66.67%),the difference was statistically significant(P＜0.05）.The postpartum blood loss in the experimental group was(209.36±22.37)ml,less than(223.14±35.18)ml in the control group,and the difference was statistically significant(P＜0.05）.The first,second and third labor stages of the experimental group were shorter than those of the control group,and the difference was statistically significant(P＜0.05）.The total duration of labor in the experimental group was(419.18±97.47)min,shorter than(531.06±110.28)min in the control group,and the difference was statistically significant(P<0.05）.The total satisfaction of the experimental group with the delivery effect was 96.67%,higher than that of the control group (82.22%),and the difference was statistically significant(P＜0.05）.
Conclusion
The method of free posture can effectively shorten the time of labor,increase the rate of natural delivery,improve the degree of satisfaction of the parturient with the effect of delivery,and suggest clinical popularization.
2019 Vol. 26 (17): 102-104 [
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54
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Effect of Montelukast on children with cough variant asthma
CHEN Yan-jun
Objective
To explore the clinical effect of Montelukast in the treatment of children with cough variant asthma.
Methods
A total of 86 children with cough variant asthma admitted to our hospital from February 2016 to February 2017 were enrolled in the observation group(43 cases)and the control group(43 cases)according to the random number table method.The control group was treated with conventional inhaled Budesonide Aerosol,and the observation group was treated with Montelukast.The clinical treatment effect,lung function index level,cough remission time,cough disappearance time,daily asthma attack number,night asthma attack frequency,short-acting bronchodilator use times,adverse reactions and recurrence were compared between the two groups.
Results
The total effective rate of the observation group was 95.35%,which was significantly higher than 79.07%of the control group,the difference was statistically significant(P<0.05).After treatment,the number of asthma attacks on the day and night of the observation group were (4.42±0.98)times/month,(3.38±1.25)times/month,and the number of short-acting bronchodilators used was(2.45±1.20)d/month,significantly less than(5.76±1.24)times/month,(4.17±0.96)times/month,(4.18±1.23)d/month in the control group,the differences were statistically significant(P<0.05).The forced expiratory volume(FEV
1
)of the observation group was(3.04±0.40)L,the forced vital capacity(FVC)was(3.89±0.56)L,and the FEV
1
/FVC was(75.93±6.14)%,which were significantly higher than(2.81±0.32)L,(3.34±0.41)L,(68.76±5.34)%in the control group,the differences were statistically significant(P<0.05).The cough relief time of the observation group was(4.01±1.24)d,and the cough disappearance time was(6.59±1.62)d,which were significantly shorter than(5.87±1.36)d,(7.94±1.58)d in the control group,the differences were statistically significant(P<0.05).The disease recurrence rate of the observation group was 9.30%after 6 months,which was significantly lower than that of the control group(30.23%),the difference was statistically significant(P<0.05).There was no significant difference in the overall incidence of adverse reactions between the two groups (P>0.05).
Conclusion
The use of Montelukast in the treatment of children with cough variant asthma can effectively improve the clinical symptoms of children,promote the normal operation of lung function,shorten the treatment time of patients,and reduce the recurrence rate of the disease.
2019 Vol. 26 (17): 105-107转111 [
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49
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Effect comparison of laparoscopic myomectomy and traditional open myomectomy in the treatment of uterine fibroids
XIA Shao-feng
Objective
To compare the effect of laparoscopic myomectomy and traditional open myomectomy in the treatment of uterine fibroids.
Methods
A total of 92 patients with uterine fibroids who admitted to our hospital from December 2016 to July 2018 were selected and divided into the control group and the study group according to random number table method,46 cases in each group.The control group was given laparoscopic myomectomy,the study group underwent laparoscopic myomectomy.After surgery,the clinical surgery-related indicators,postoperative conditions,adverse reactions and immune system indicators were compared between the two groups.
Results
After surgery,in terms of the clinical surgery-related indicators,the amount of intraoperative blood loss in the study group was lower than that in the control group.The anal exhaust time and length of hospital stay were shorter than those in the control group,the differences were statistically significant(P<0.05).In terms of the surgery time,the study group was longer than in the control group,and the difference was statistically significant(P＜0.05）;in terms of the postoperative conditions,the postoperative prevalence rate,postoperative analgesia application rate,and postoperative residual incidence rate in the study group were lower than in the control group and the differences were statistically significant.In terms of the postoperative recurrence,the incidence rate in the study group was higher than that in the control group,and the differences were statistically significant(P＜0.05）.In terms of the adverse reactions,the total incidence rate in the study group was lower than that in the control group,and the difference was statistically significant(P＜0.05）;in terms of the immune system index,the IgG and IgA levels in the study group were higher than those in the control group,and the differences were statistically significant(P＜0.05）.In terms of IgM,the difference between the two groups was not significant,and there was no statistical significance(P＞0.05）.
Conclusion
Compared with traditional open myomectomy in the treatment of uterine fibroids,laparoscopic myomectomy has a significant effect,less adverse reactions,better postoperative conditions,and a higher clinical value,which is worthy of promotion.
2019 Vol. 26 (17): 108-111 [
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53
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Effect of laparoscopic surgery combined with Leuprorelin on ovarian reserve function and fertility in patients with ovarian endometriotic cyst
GE Hong
Objective
To explore the effect of laparoscopic surgery combined with Leuprorelin on ovarian reserve function and fertility in patients with ovarian endometriosis cyst.
Methods
A total of 200 patients with ovarian endometriosis cyst admitted to our hospital from November 2016 to November 2017 were selected as the research objects,they were divided into control group and observation group according to the dynamic random method,100 cases in each group.The control group was treated with laparoscopic ovarian endometriosis cyst removal,while the observation group was treated with Leuprorelin on the basis of the control group.The levels of serum follicle stimulating hormone(FSH),luteinizing hormone (LH)and estradiol(E
2
),recurrence rate,time of second pregnancy and rate of second pregnancy were compared between the two groups.
Results
After treatment,the FSH level in the observation group was lower than that in the control group,and the LH and E
2
levels were higher than those in the control group,the differences were statistically significant(P＜0.05).The recurrence rate of the observation group was 5.00%,which was lower than 19.00%of the control group,the difference was statistically significant(P＜0.05).The second pregnancy time of the observation group was shorter than that of the control group,the difference was statistically significant(P＜0.05).The second pregnancy rate of the observation group was 77.80%,which was higher than 35.30%of the control group,the difference was statistically significant(P＜0.05).
Conclusion
Laparoscopic ovarian endometriosis cystectomy combined with Leuprorelin in the treatment of ovarian endometriosis cyst can improve ovarian reserve function,improve pregnancy rate,shorten pregnancy time and significantly reduce the recurrence rate,which is worthy of clinical application.
2019 Vol. 26 (17): 112-114 [
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67
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Application effect of minimally invasive extraction technique in extraction of impacted mandibular wisdom teeth
ZHEN Dong； HUANG Rong； NIE Zi-lin
Objective
To compare and observe the effect and safety of minimally invasive extraction and traditional extraction in the extraction of impacted mandibular wisdom teeth,so as to provide reference for the selection of surgical treatment
Methods
in the future.
Methods
A total of 5000 patients with unilateral impacted mandibular wisdom teeth in the Department of Stomatology of our hospital and the First People′s Hospital of Huizhou City from January 2016 to April 2019 were selected as observation samples.They were randomly divided into the control group and the observation group,with 2500 cases in each group.The control group was treated with traditional tooth extraction (chisel and crown splitting),and the observation group was treated with high-speed turbines and long splitting,minimally invasive tooth extraction combined with drill and minimally invasive tooth extraction knife.The operation time of the two groups was compred,and visual analogue scale score was used to evaluate the degree of pain after operation in the two groups.The complications of the two groups were recorded the occurrence of perioperative complications.
Results
The operation time of the observation group was(17.75±3.53)min,which was significantly shorter than (33.16±6.24)min of the control group,with statistical significance (P＜0.05).The pain degree of the observation group was significantly better than that of the control group,with statistical significance (P＜0.05).The total incidence of perioperative complications in the observation group was 19.16%,which was significantly lower than that in the control group(50.32%),with statistical significance(P＜0.05).
Conclusion
Minimally invasive extraction of impacted mandibular wisdom teeth has shorter operation time,with less pain,lower incidence of perioperative complications and high safety.It can be used as the preferred method in clinical promotion and application.
2019 Vol. 26 (17): 115-117转136 [
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75
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Effect comparison of minimally invasive extraction and traditional tooth extraction in the extraction of mandibular impacted tooth
LIU Xiao-bing； CHEN Mian
Objective
To investigate the different effects of minimally invasive extraction and traditional tooth extraction in the extraction of mandibular impacted tooth.
Methods
A total of 100 patients with mandibular impacted teeth who were admitted to our hospital from January to December 2017 were selected as study subjects.They were divided into control group(50 cases)and observation group(50 cases)by random number table method.The control group was given traditional tooth extraction.The observation group was given minimally invasive extraction by high-speed turbine drilling.The degree of mouth opening restriction,operation time,tooth extraction integrity,patients′pain degree and complications were compared between the two groups.
Results
The integrity of tooth extraction in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The operation time in the observation group was significantly shorter than that in the control group,the mouth opening restriction and the swelling degree were significantly weaker than those in the control group,the incidence rate of complications was significantly lower than that in the control group,and the differences were statistically significant(P＜0.05).
Conclusion
The minimally invasive tooth extraction by high-speed turbine drilling for mandibular impacted tooth extraction can reduce the patients′pain,improve the integrity of tooth extraction,and is more conducive to patients′recovery.
2019 Vol. 26 (17): 118-120 [
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] (
55
)
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121
Clinical study of lacrimal passage probing combined with Tobramycin and Dexamethasone Eye Ointment in the treatment of infant lacrimal passage obstruction
LI Min-ping; DENG Qi-lin; WEN Jiang-jiang
Objective
To explore the clinical effect of lacrimal passage probing combined with Tobramycin and Dexamethasone Eye Ointment in the treatment of infant lacrimal passage obstruction.
Methods
A total of 100 children with lacrimal duct obstruction admitted to our hospital from January 2018 to January 2019 were randomly divided into study group(50 cases)and control group(50 cases).The control group was treated with lacrimal passage probing alone,while the study group was treated with lacrimal passage probing combined with Tobramycin and Dexamethasone Eye Ointment.The total effective rate and recurrence rate of the two groups were compared,and the total satisfaction degree of the family members of the two groups was compared.
Results
The total effective rate of treatment and the total satisfaction of family members in the study group were significantly higher than those in the control group,the differences were statistically significant(P<0.05).The recurrence rate in the study group was significantly lower than that in the control group after 1 or 3 months of follow-up,the differences were statistically significant(P<0.05).
Conclusion
Lacrimal passage probing combined with Tobramycin and Dexamethasone Eye Ointment filling therapy for children with lacrimal passage obstruction can significantly improve the clinical efficacy of children,reduce the recurrence rate,but also increase the satisfaction of family members of children with treatment,which can be vigorously promoted in clinical practice.
2019 Vol. 26 (17): 121-123 [
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] (
62
)
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124
Clinical efficacy of Duraphat in preventing secondary caries in permanent teeth of adolescents
FEI Hong-you; LIN Bi-le
Objective
To study the clinical effect of Duraphat in preventing secondary caries in permanent teeth of adolescents after filling treatment.
Methods
All of 203 cases of bilateral permanent mandibular first molars with caries treated in the Dental clinic of Shenzhen Children′s Hospital from September 2015 to September 2016 were selected.One side mandibular first molars were randomly selected as the experimental group while the other side as the control group.The teeth of experimental group were applied with Duraphat after filling treatment and regular reviews after 3 months,6 months,12 months and 24 months,while the teeth of control group were given oral hygiene education.The occurrence of secondary caries after filling treatment was recorded in both groups.
Results
There was no significant difference in the incidence of secondary caries between the two groups after 3 and 6 months(P＞0.05).The incidence of secondary caries in the experimental group was lower than that in the control group after 12 and 24 months,the difference was statistically significant(P＜0.05).
Conclusion
Regular application of Duraphat can effectively prevent secondary caries in adolescents and reduce the incidence of secondary caries after filling treatment.
2019 Vol. 26 (17): 124-126 [
Abstract
] (
76
)
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127
Effect of Calcium Hydroxide Paste treating children with periapical periodontitis
HUANG Jian-huai; FU Long-sheng; LAI Hai-yan; YANG Xiao-ying; LAI Yue-ming; XIAO Zhen-peng
Objective
To explore the clinical effect of calcium hydroxide paste in the treatment of children with periapical periodontitis.
Methods
All of 150 children with periapical periodontitis admitted to Yingde People′s Hospital from June 2016 to June 2018 were selected as study subjects and they were divided into the study group and reference group according to the random number table method,with 75 cases in each group.The reference group was treated with Camphor Phenol,while the study group was treated with Calcium Hydroxide Paste.The clinical efficacy,the pain grade and the incidence of adverse reactions were compared between the two groups.
Results
The total effective rate of treatment in the study group was 94.67%,which was significantly higher than that of the reference group(78.67%)(P＜0.05).The pain grade of the study group was significantly better than that of the reference group(P＜0.05).In the study group,there was 1 case of periapical tissue inflammation,1 case of nausea and vomiting,and 1 case of skin itching,while in the reference group,there were 8 cases of periapical tissue inflammation,2 cases of nausea and vomiting,and 1 case of diarrhea.The total incidence of adverse reactions in the study group(4.00%)was significantly lower than that in the reference group(14.67%)(P＜0.05).
Conclusion
Calcium hydroxide paste treating children with periapical periodontitis is exact and it can effectively improve the clinical therapeutic effect,significantly reduce the pain of illed children,significantly reduce the incidence of adverse reactions,and has a higher safety.
2019 Vol. 26 (17): 127-129 [
Abstract
] (
47
)
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130
Effect comparison of polymer resin restoration and porcelain inlay restoration combined with root canal therapy in the treatment of posterior tooth defects
LI Yan-Fen
Objective
To observe and compare the effects of polymer resin restoration and porcelain inlay restoration combined with root canal therapy in the treatment of posterior tooth defects.
Methods
From April 2014 to April 2015,100 patients with posterior teeth defect were divided into group A and group B according to random number table method,50 patients in each group.Patients in group A were treated with polymer resin restoration combined with root canal therapy,while patients in group B were treated with polymer porcelain inlay restoration combined with root canal therapy.After the treatment,the patients were followed up for 3 years,the efficiency,adverse reactions and the satisfaction of the two groups were compared.
Results
The effective rate in group B was significantly higher than in group A,difference between the two groups had statistical significance (P＜0.05).The total adverse reaction rate in group B was significantly lower than in group A,difference between the two groups had statistical significance(P＜0.05).The total satisfaction rate of group B was significantly higher than group A,difference between the two groups had statistical significance(P＜0.05).
Conclusion
Polymer porcelain inlay combined with root canal therapy for tooth defect is effective and has less adverse reactions,higher satisfaction.It is suggested that it should be popularized in clinic.
2019 Vol. 26 (17): 130-132 [
Abstract
] (
60
)
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133
Effect of Propofol combined with Sevoflurane anesthesia on hemodynamics and narcotrend index of laparoscopic high ligation of hernia sac in children
ZHANG Ling; YIN Zheng-chun; YE Zhu-ying; FU Shui-qing; LIU Zhen-ming
Objective
To investigate the effect of Propofol combined with Sevoflurane anesthesia on hemodynamics and narcotrend index(NI)of laparoscopic high ligation of hernia sac in children.
Methods
Ninety-nine children who underwent laparoscopic high ligation of hernia sac in our hospital from March 2015 to March 2016 were selected as the research objects.They were divided into group A,group B and group C according to the random sampling method,33 cases in each group.The group A received single Propofol anesthesia,the group B received single Sevoflurane anesthesia,while the group C received Propofol combined with Sevoflurane anesthesia.The NI,heart rate(HR),mean arterial pressure (MAP),and oxygen saturation (SpO
2
)before and after surgery were compared in the three groups.The total incidence rate of adverse reactions in the three groups of children was counted.
Results
There was no significant difference in NI among the three groups before surgery (P＞0.05).The NI of the three groups after surgery was lower than that before surgery,and the difference was statistically significant(P＜0.05).The NI of group C after surgery was higher than that of group A and group B,and the differences were statistically significant(P＜0.05).There was no significant difference in the NI between group A and group B after surgery(P＞0.05).There were no significant differences in HR,MAP and SpO
2
among the three groups before surgery(P＞0.05).The HR after surgery in the three groups was lower than that before surgery,the MAP and SpO
2
were higher than those before surgery,and the differences were statistically significant (P＜0.05).The HR of group C after surgery was higher than that of group A and group B,the MAP and SpO
2
were lower than those of group A and group B,and the differences were statistically significant(P＜0.05).There were no significant differences in the HR,MAP and SpO
2
between group A and group B after surgery(P＞0.05).The total incidence rate of adverse reactions in group C was lower than that in group A and group B,and the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence rate of adverse reactions between group A and group B(P＞0.05).
Conclusion
Clinically,the combined anesthesia of Propofol and Sevoflurane can stabilize hemodynamics in children undergoing laparoscopic high ligation of hernia sac.
2019 Vol. 26 (17): 133-136 [
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] (
64
)
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137
Clinical effect of Oxcarbazepine combined with Flupentixol and Melitracen Tablets in the treatment of patients with primary trigeminal neuralgia
CHEN Rui
Objective
To explore the clinical effect of Oxcarbazepine combined with Flupentixol and Melitracen Tablets in the treatment of patients with primary trigeminal neuralgia(PTN).
Methods
A total of 68 PTN patients treated in our hospital from October 2016 to October 2018 were selected and divided into the study group (n=34)and the control group (n=34)according to random number table method.Patients in the control group were given Oxcarbazepine,and those in the study group were given Oxcarbazepine combined with Flupentixol and Melitracen Tablets.Both groups were treated for 3 months.The clinical effects,the incidence of adverse reactions,and the scores of visual analogne scale(VAS)and Pittsburgh sleep quality index scale(PSQI)before treatment and 1 month and 3 months after treatment were compared between the two groups.
Results
After 3 months of treatment,the overall effective rate of the study group was 94.12%(32/34),which was higher than 73.53%(25/34)of the control group(P＜0.05).There was no significant difference in the VAS and PSQI scores between the two groups before treatment(P＞0.05),and both scores were reduced in both groups at 1 and 3 months after treatment,and those in the study group were lower than those in the control group (P＜0.05).The total incidence of adverse reactions in the study group was 17.65%,and there was no significant difference between the experimental group and the control group (8.82%)(P＞0.05).
Conclusion
Oxcarbazepine combined with Flupentixol and Melitracen Tablets can improve the clinical effect in the treatment of patients with primary trigeminal neuralgia,relieve the pain of patients,improve the sleeping quality,and have high safety.
2019 Vol. 26 (17): 137-139转144 [
Abstract
] (
76
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140
Effect comparison of Propofol and Etomidate combined with Sufentanil in anesthesia of lingual frenoplasty
GU Hai-fei； CHENG Li-ming； ZHANG Ming； ZHANG Xin
Objective
To compare the effect of Propofol and Etomidte combined Sufentanil in anesthesia of lingual frenoplasty.
Methods
A total of 110 children with ASAⅠ-Ⅱ who underwent elective lingual frenoplasty in Kunming Children′s Hospital from June to October 2018 were selected as subjects.They were divided into Propofol-Sufuftanil intravenous anesthesia group (group P)and Etomidate-Sufuftanil intravenous anesthesia group (group E)according to the random number table method,55 cases in each group.The hemodynamic parameters(heart rate[HR],systolic blood pressure [SBP],diastolic blood pressure [DBP],mean arterial pressure [MAP],pulse oxygen saturation [SpO
2
])were recorded before the induction of anesthesia(T
1
),after anesthesia induction(T
2
),during surgery(T
3
),and waking up(T
4
).The anesthesia induction time,operation time,recovery time,and total incidence rate of adverse reactions were compared between the two groups.
Results
There were no significant differences in anesthesia induction time and operation time between the two groups(P＞0.05).The recovery time of children in group E was shorter than that in group P,and the difference was statistically significant(P＜0.05).There were no significant differences in DBP,SBP,MAP,HR and SpO
2
between the two groups at T
1
and T
4
(P＞0.05).The DBP,SBP,MAP,HR and SpO
2
at T
2
,T
3
and T
4
in the two groups were lower than those at T
1
,and the differences were statistically significant(P＜0.05).The DBP,SBP,MAP,HR and SpO
2
at T
2
and T
3
in group E were higher than those in group P,and the differences were statistically significant(P＜0.05).The total incidence rate of adverse reactions in group E was 54.5%,which was lower than that in group P(90.9%),and the difference was statistically significant(P＜0.05).
Conclusion
The Etomidte combined with Sufentanil has stable hemodynamics,with smooth anesthesia,less intraoperative adverse reactions,comfort postoperative recovery,and good safety.
2019 Vol. 26 (17): 140-144 [
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] (
75
)
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145
Clinical effect comparison of Dizocine and Remifentanil combined with Propofol in anaesthesia of painless artificial abortion
SUN Hong-tao； HE Wen-wei； YIN Guang-fen
Objective
To investigate the differences between the effects of Dizocine and Remifentanil combined with Propofol in the anesthesia of painless artificial abortion.
Methods
A total of 100 patients receiving painless artificial abortion who were admitted to our hospital from January to December 2018 were selected as the study subjects.The computerized randomization principle was used to divide the patients into the observation group(50 cases)and the control group(50 cases).Patients in the observation group were given Dizocine combined with Propofol for anesthesia,and patients in the control group were given Remifentanil combined with Propofol for anesthesia.The recovery time,postoperative digital pain assessment(NRS)score,mean arterial pressure(MAP),anesthetic effect,and adverse reactions were compared between the two groups.
Results
There was no statistically significant difference in the conscious time and orientation recovery time between the two groups(P＞0.05).The postoperative NRS score of the observation group was lower than that of the control group,and the difference was statistically significant(P＜0.05).The MAP in the observation group was higher than that in the control group,the anesthetic effect was better than that in the control group,the total incidence rate of adverse reactions was lower than that in the control group,and the differences were statistically significant(P＜0.05).
Conclusion
The overall effects of Dizocine combined with Propofol were better than the effects of Remifentanil combined with Propofol for the anesthesia of painless artificial abortion,and the adverse reactions are under control.
2019 Vol. 26 (17): 145-147 [
Abstract
] (
73
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148
Clinical effect of Tonifying Qi and Phlegm on hypertension
XIE Hui-jun
Objective
To explore the clinical effect of Tonifying Qi and Phlegm therapy in the treatment of hypertension.
Methods
From May 2017 to August 2018,88 patients with hypertension in our hospital were selected as the object of study and patients were divided into control group (n=44)and test group (n=44)according to computer grouping method.The control group was treated with routine western medicine.On the basis of this,the test group increased Tonifying Qi and Phlegm therapy.The clinical symptom score,blood pressure level,blood lipid level,internal carotid artery hemodynamics index,incidence rate of adverse reactions and total effective rate of treatment were compared between the two groups.
Resluts
The clinical symptom score and blood pressure level of the test group were significantly lower than the control group.The differences were statistically significant(P<0.05）.The test group had cholesterol,triglyceride,low-density lipoprotein,end-diastolic flow velocity and systole,the peak flow rate,intravascular-medial thickness was lower than that of the control group,and high-density lipoprotein was higher than that of the control group,the differences were statistically significant(P<0.05）.Both groups had mild nausea,dizziness,facial flushing and other adverse reactions,effective mitigation after proper treatment.There was no significant difference in adverse reactions between the two groups(P＞0.05）.The total effective rate of the test group was significantly higher than that of the control group,the difference was statistically significant(P<0.05）.
Conclusion
The method of Tonifying Qi and Phlegm can not only improve the clinical symptoms,blood pressure and blood lipid level,but also relieve the internal carotid artery hemodynamics,improve the effect of carotid protection,and be used in clinical treatment.The adverse reaction is less,the safety is high,the clinical treatment effect is remarkable,it is worth popularizing.
2019 Vol. 26 (17): 148-150 [
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] (
70
)
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151
Effect of integrated traditional Chinese and western medicine on diabetic peripheral neuropathy and its influence on serum levels of homocysteine and cystatin-C
ZENG Li-sheng； OUYANG Chun-xi
Objective
To explore the effect of integrated traditional Chinese and western medicine on diabetic peripheral neuropathy(DPN)patients and levels of homocysteine(Hcy)and cystatin-C(Cys-C)in serum.
Methods
A total of 124 DPN patients in our hospital from October 2015 to June 2018were selected and randomly divided into experimental group and control group,62 cases in each group.On the basis of basic drug treatment,the patients in control group were given 500 μg Mecobalamin Injection once a day.The experimental group was treated with Huangqi Xuanshen Decoction on the basis of the control group.After two courses of treatment,toronto clinical score(TCSS),sensory nerve conduction velocity(SNCV),motor nerve conduction velocity(MNCV)and levels of HCY and Cys-C were compared between the two groups,in order to evaluate the therapeutic effect of traditional western medicine basic treatment plus Huangqi Xuanshen Decoction on diabetic peripheral neuropathy.
Results
After two courses of treatment,the total effective rate of the experimental group was higher than that of the control group(P<0.05）;the TCS score of the experimental group was lower than that of the control group(P<0.05）;the NCV and SNCV of the experimental group were higher than those of the control group(P<0.05）;the levels of HCY and Cys-C of the experimental group were lower than those of the control group,and the differences were statistically significant(P<0.05）.
Conclusion
The combination of traditional Chinese medicine and western medicine has a significant effect on DPN patients.Moreover,this therapy can significantly reduce the levels of HCY and Cys-C in serum.
2019 Vol. 26 (17): 151-153转156 [
Abstract
] (
57
)
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18
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154
Effect of plum blossom needle-punching combined with thermal moxibustion treating post-herpetic neuralgia in elderly patients with herpes zoster
KONG Yu； LIU Jun； CAI Xuan； LI Jian-feng； LIU Chun-yang； LI Min
Objective
To investigate the effect of plum blossom needle acupuncture combined with heat-sensitive moxibustion on post-herpetic neuralgia in elderly patients with herpes zoster （HZ）.
Methods
A total of 50 elderly patients with postherpetic neuralgia who treated in our hospital from March 2016 to March 2017 were selected and randomly divided into the control group and the observation group,25 cases in each group.The control group was treated with carbamazepine,the observation group was treated with plum blossom needle and acupuncture combined with heat-sensitiv moxibustion,the sleep quality score,skin lesion degree score,visual analogy score (VAS)and total effective rate were compared between two groups.
Results
After treatment,the sleep quality score,skin lesion score and VAS score of the observation group were lower than the control group,the differences were statistically significant(P<0.05）.The total effective rate of the observation group (96.00%)was higher than that of the control group (72.00%),the difference was statistically significant(P<0.05).
Conclusion
Plum blossom needle acupuncture combined with heat-sensitive moxibustion can effectively improve the prognosis of patients with postherpetic neuralgia in the elderly,which is worthy of popularization.
2019 Vol. 26 (17): 154-156 [
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] (
59
)
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157
Application effect of self-blood acupoint injection in the treatment of bronchial asthma
YANG Yu-zhen; HUANG Cheng-zhi; ZHOU Juan; CHEN Bing; LU Hai-ling
Objective
To investigate the effect of self-blood point injection in the treatment of bronchial asthma(BA).
Methods
From May 2016 to May 2018,76 patients with BA admitted in our hospital were selected and divided into the observation group and the control group according to random number table method,38 cases in each group.The control group was treated with Beclomethasone Propionate Aerosol inhalation and Doxofylline intravenous drip.On the basis of the control group,the patients in the observation group were treated with self-blood injection at acupoint.The clinical efficacy,pulmonary function index,serum IgE and eosinophil count were compared between the two groups before and after treatment,and the recurrence of asthma in the two groups was compared after half a year follow-up.
Results
The total effective rate of treatment in the observation group was 92.11%,which was higher than that in the control group (73.68%)(P<0.05）.Before treatment,there was no significant difference in forced vital capacity(FVC),forced expiratory volume (FEV
1
)level,serum IgE and eosinophil count between the two groups (P＞0.05）.After treatment,the level of FVC,FEV
1
in the observation group was higher than that in the control group,and the levels of serum IgE and eosinophil were significantly lower than those of the control group (P<0.05）.The recurrence rate in the observation group was 7.89%,which was lower than that in the control group(23.68%)(P<0.05）.There was no statistical significance in the incidence of adverse reactions between the two groups(P＞0.05）.
Conclusion
Doxotheophylline combined with self-blood acupoint injection can effectively improve the clinical efficacy,reduce the airway stress response,improve lung function,reduce the recurrence of asthma,and is safe and worthy of clinical promotion.
2019 Vol. 26 (17): 157-159 [
Abstract
] (
69
)
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160
Effect of acupoint application on postoperative gastrointestinal dysfunction in patients with spinal cord injury
YU Na; ZHANG Yun-hai; MA Ming-yuan
Objective
To investigate the effect of evodia acupoint application on postoperative gastrointestinal dysfunction(GD)in patients with spinal cord injury(SCI).
Methods
From January 2016 to December 2018,90 cases hospitalized in our hospital with SCI after surgery were selected and randomly divided into the control groups and the observation group,45 cases in each group.The control group was received routine monitoring and supportive treatment.On the basis of the control group,the observation group were given evodia rutaecarpa acupoints(zhongwan,tsuanli and dachangshu acupoint).The levels of C-reactive protein (CRP)were measured and the clinical effects were compared between the two groups.
Results
The levels of CRP in D
1
,D
3
and D
5
in the observation group were lower than controls(P<0.05）.The gastrointestinal symptoms scores and clinical effect of the observation group(82.22%)was significantly higher than that of the control group(53.33%)(P<0.05).
Conclusion
Acupoint application can reduce the inflammatory reaction of patients with SCI after operation,and has a certain therapeutic effect on GD after operation.
2019 Vol. 26 (17): 160-162 [
Abstract
] (
72
)
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8
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163
Clinical study of acupuncture and moxibustion combined with intermittent urinary catheterization in the treatment of urinary dysfunction in stroke patients
LI Feng; WEN Zhen-yu; ZHANG Jun-hui; HU Ping; XIE Qian-yu; GAN Ke
Objective
To analyze the improvement of urinary dysfunction in patients with stroke by acupuncture and moxibustion combined with intermittent urinary catheterization.
Methods
Sixty patients with stroke admitted to our hospital from February 2017 to May 2018 were selected as the research objects,they were randomly divided into control group(30 cases)and observation group(30 cases).The control group was treated with indwelling catheter,while the observation group was treated with acupuncture and moxibustion combined with intermittent urinary catheterization.The remission time of symptoms,residual urine volume,daily living ability score,positive and negative detection of Urinary Routine leukocytes were compared between the two groups.
Results
The remission time of symptoms in the observation group was shorter than that in the control group,and the residual urine volume was less than that in the control group,the differences were statistically significant(P＜0.05).The daily living ability score of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).The positive rate of leucocyte in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).
Conclusion
Acupuncture and moxibustion combined with intermittent urinary catheterization can effectively improve the condition of voiding disorder,which is worthy of further promotion.
2019 Vol. 26 (17): 163-165 [
Abstract
] (
63
)
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166
Application effect of Baogong Fuyuan Decoction combined with Estradiol Valerate Tablets in patients with induced abortion
WANG Bo-wen; ZHANG Ai-lian
Objective
To explore the application effect of Baogong Fuyuan Decoction combined with Estradiol Valerate Tablets in the treatment in patients with induced abortion.
Methods
A total of 126 patients of induced abortion in our hospital from June 2017 to June 2018 were randomly divided into study group (n=63)and control group (n=63).The control group was treated with Baogong Fuyuan Decoction,while the study group was treated with Baogong Fuyuan Decoction combined with Estradiol Valerate Tablets.The therapeutic effect,serum levels of epidermal growth factor(EGF),interleukin-1 (IL-1)and complications were compared between the two groups.
Results
The total effective rate of clinical treatment in the study group was significantly higher than that in the control group,the difference was significant(P＜0.05).There was no significant difference the levels of EGF and IL-1 in serum between the two groups before treatment(P＞0.05).The levels of EGF and IL-1 in serum of the two groups after treatment were higher than those before treatment,the differences were statistically significant(P＜0.05).After treatment,the level of serum EGF in the study group was lower than that in the control group,and the level of IL-1 was higher than that in the control group,the differences were statistically significant(P＜0.05).The total incidence of complications in the study group was lower than that in the control group,the difference was significant(P＜0.05).
Conclusion
The application of Baogong Fuyuan Decoction combined with Estradiol Valerate Tablets in the treatment of induced abortion can not only improve the effect of endometrial repair and prevention of uterine adhesions,but also improve the serum levels of EGF and IL-1,which is worthy of clinical application.
2019 Vol. 26 (17): 166-168 [
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] (
64
)
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169
Effect analysis of promoting hepatocyte regeneration by integrated traditional Chinese and western medicine in the treatment of liver cirrhosis
CUI Shu-wang； SUN Zhan-hai； DONG Ya-juan； LIU Hai-tao； SUN Zhong-xing
Objective
To explore the effect of promoting liver cell regeneration by integrated traditional Chinese and western medicine in the treatment of liver cirrhosis.
Methods
A total of 224 patients with decompensated cirrhosis from June 2013 to October 2016 were selected as the study subjects.They were divided into experimental group and control group according to random number table method,112 cases in each group.The patients in the control group were given routine treatment,while those in the experimental group were given integrated traditional Chinese and western medicine to promote liver cell regeneration.The clinical therapeutic effect and drug safety were compared and analyzed.The indexes of liver function and serum hepatic fibrosis were compared between the two groups.
Results
The total effective rate was 90.18%in the experimental group,which was significantly higher than 80.36%in the control group (P＜0.05).After treatment,the level of alpha-fetoprotein(AFP)in the experimental group was(17.00±2.31)U/ml,which was significantly lower than that in the control group([27.0±2.34]U/ml)(P＜0.05);the level of aspartate amino transferase(AST)was(43.62±7.69)U/L,which was significantly lower than that in the control group([86.47±12.58]U/L)(P＜0.05);the level of TBIL was(21.96±4.09)mol/L,which was significantly lower than that in the control group ([64.29±9.72]mol/L)(P＜0.05);the white ball ratio(A/G)was(0.80±0.37),significantly higher than that of the control group(0.60±0.21)(P＜0.05).After treatment,hyaluronic acid(HA)level in the experimental group was(300.53±107.53)μg/L,significantly lower than that in the control group([537.19±128.46]μg/L)(P＜0.05);laminin(LN)level was(96.33±26.17)μg/L,significantly lower than that in the control group([128.74±30.51]μg/L)(P＜0.05);Ⅲ procollagen(PCⅢ)level was(142.63±31.05)μg/L,significantly lower than that in the control group([167.49±40.11]μg/L)(P＜0.05).There was no significant difference in the incidence of side effects between the two groups after treatment(P＞0.05),and the side effects disappeared after symptomatic treatment.
Conclusion
The combination of traditional Chinese and western medicine in promoting liver cell regeneration in the treatment of liver cirrhosis has significant clinical effect,significantly reduces the biochemical indicators of patients,and the incidence of side effects is low,so it has high application clinical value.
2019 Vol. 26 (17): 169-171转175 [
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] (
64
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172
Analysis of influencing factors of erectile dysfunction in male work injury patients in the Pearl River Delta
LIN Yue-qing； OUYANG Ya-tao； DENG Wen-hua； LI Hui-mei； Xiang Dan
Objective
To analyze the influencing factors of erectile dysfunction(ED)in male work injury patients in the Pearl River Delta.
Methods
A total of 430 male work injury patients were investigated,who had been hospitalized for more than three months in nine industrial injury rehabilitation hospitals in the Pearl River Delta from January to December 2016.The age,education level,disease course,disease type and other research indicators of patients were collected through medical records,and the erectile function in the past 3 months was evaluated by the erectile function international questionnaire.The recovery rate of the questionnaire was 95.6%,and the number of valid cases was 411 cases.About 75.2%of patients had varying degrees of ED.According to whether there was ED,they were divided into ED group(n=309)and non-ED group(n=102).
Results
The age of the ED group was(41.1±8.7)years old,which was higher than that of the non-ED group for(37.8±7.7)years old,the proportion of rural population was 65.0%,which was higher than that of the non-ED group (53.9%),the proportion of spinal cord injury was 15.2%,which was significantly higher than 2.9%in non-ED group,culture with junior high school and below was 58.3%,which was significantly higher than 35.3%in non-ED group,depression and anxiety accounted for 74.8%and 66.0%,respectively,which was significantly higher than 31.4%and 25.5%in non-ED group,and the proportion of disease was 19.1%,which was significantly higher than 9.8%in the non-ED group,with the statistically significant differences (P＜0.05).The spouse life satisfaction score of the ED group was(3.2±0.9)points,which was significantly higher than that of the non-ED group for (1.9±0.7)points,and the difference was statistically significant(P＜0.05).Logistic regression analysis showed that disease,depression,education level,age and spouse life satisfaction were influencing factors of ED （P＜0.05）.
Conclusion
The age,disease type,depression and husband-wife relationship are risk factors of ED,which should be paid enough attention.
2019 Vol. 26 (17): 172-175 [
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Distribution study of common types of human papillomavirus in patients with cervical precancerous lesions in our hospital
CHEN Peng； GUO Gui-lin； LENG Wei-xiang； YANG Qing-ping； HUANG Ying-bei
Objective
To investigate the distribution of common types of human papillomavirus(HPV)in patients with cervical precancerous lesions in our hospital.
Methods
The clinical data of 157 patients with cervical intraepithelial neoplasia(CIN)treated in our hospital from January 2017 to February 2018 were retrospectively analyzed.According to the results of histopathological examination,they were divided into the CINⅠgroup (56 cases),the CINⅡgroup(37 cases)and the CINⅢgroup(64 cases).The HPV infection and the distribution of common types of HPV in each group were compared.
Results
The infection rate of HPV was 70.06%in 157 CIN patients.A total of 13 types of HPV were detected in CIN patients,including HPV 16,58,52,33,31 and 51.The low-risk subtypes accounted for 9.09%and the high-risk subtypes accounted for 90.91%of the patients with HPV infection in the CINⅠgroup.The low-risk subtypes accounted for 2.27%and the high-risk subtypes accounted for 97.73%in the patients with HPV infection in CINⅡgroup;and the high-risk subtypes accounted for 100.00%in the patients with HPV infection in the CINⅢgroup.
Conclusion
High-risk HPV infection is the main cause of CIN.HPV 16 is the subtype of HPV with high infection rate.The higher the grade of cervical intraepithelial neoplasia,the higher the HPV infection rate,and the higher the risk of high-risk subtype infection.
2019 Vol. 26 (17): 176-178 [
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63
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179
Analysis of Cornell health questionnaire for senior high students in Jiangmen city
CHEN Li-qiu
Objective
To understand the physical and mental health status of senior high students in Jiangmen city,and to provide suggestions for targeted health education.
Methods
A cluster random sampling method was used to select research objects in 11 schools in Jiangmen city from May to June 2018.One hundred senior high students from these 11 schools each were randomly selected to conduct a Cornell health questionnaire survey,totaling 1100.The total scoring(A-R)and the psychiatric symptom(M-R)scoring were used for evaluation,and the correlation between somatic health status and mental health status was analyzed.
Results
There were 205 students diagnosed with physical and mental health disorders and 155 students with abnormal mental symptoms after investigation.The higher positive response rates were eye and ear,habit,inadaptation,depression,sensitivity,nervousness,anger,and so on.The A-R and M-R values of male students were both lower than those of female ones with statistical significance(P＜0.05).The A-R and M-R values of rural students were higher than those of urban students (P＜0.05).There was no significant difference in the A-R value or M-R value of the only-child students compared with the non-only child students(P＞0.05).The A-R and M-R values didn′t differ statistically in students whose parents were in different educational levels(P＞0.05).The somatic health status and the mental health status interacted with each other,and the two were positively related to the physical and mental health status (r=0.93,0.86,P＜0.05).
Conclusion
The positivity rate of screening for physical and mental disorders in senior high students was 19.07%.The incidence of physical and mental disorders in girls and rural students was high.
2019 Vol. 26 (17): 179-182 [
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54
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183
Retrospective analysis of pre-interventions for irrational prescriptions of outpatient clinics in our hospital
FU Yan； YANG Fu-ying； LI Ping； JIANG Shao-qing； JIA Le-chuan
Objective
To understand the pre-interventions for irrational prescriptions in outpatient clinics and to promote rational use of drugs in outpatient clinics.
Methods
The unreasonable prescriptions in outpatient clinics with preinterventions of Cancer Hospital of General Hospital of Ningxia Medical University from January to December 2016 were collected,classified,counted and evaluated,and the causes and avoidance measures were analyzed.
Results
According to statistics,in 403 unreasonable prescriptions with pre-intervention,352 prescriptions were not standardized,44 prescriptions were not suitable for medication,7 were abnormal prescriptions,and 327 prescriptions recommended by pharmacists were accepted by physicians,with an intervention success rate of 81.14%.
Conclusion
Through pharmacist review,pre-intervention of unreasonable prescriptions can reduce and prevent the occurrence of irrational use of drugs in a timely manner,thereby effectively ensuring the quality of prescriptions and regulating the safety and rationality of patient medication.
2019 Vol. 26 (17): 183-185转189 [
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56
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Pathogenic characteristics of children with lower respiratory tract infection in our hospital
LI Zi-qiang; LIU Xiao-yue; Huang Yi-shuang; LANG Xin-ling; LIU Xi; HUANG Wei-dong
Objective
To study the etiological characteristics of children with lower respiratory infection (LRI)in our hospital.
Methods
A total of 435 children with clinical diagnosis of LRI from September 2016 to September 2018 were selected in our study.Childrens were examined and treated with Olympus BF-XP260 bronchoscopy(2.8 mm/4.0 mm).Bacteria in the sputum were separated,identified and tested by Bd Phoenix
TM
M50 automatic microbial identification and drug sensitivity analysis system.
Results
At least one pathogen was detected in 113 out of 435 patients and the overall positive rate was 25.98%.A total of 421 strains were obtained,among which 331 strains were gram-negative strains(78.62%),90 strains were gram-positive strains (21.38%).Gram-negative pathogens were insensitive to most antibiotics,especially to ampicillin.Among gram-positive pathogens,Staphylococcus aureus(MRSA)was sensitive to vancomycin and insensitive to other antibiotics;Streptococcus pneumoniae was insensitive to erythromycin and sensitive to other antibiotics.The detection rates of MRSA,multi-drug resistant pseudomonas (MDR-PA),multidrug-resistant acinetobacter baamannii(MDR-AB),extended-spectrum lactamasa klebsiella peeumoniac(ESBLs)(Klebsiella pneumoniae and Escherichia coli)were 52.46%,32.53%,34.72%,35.29%and 32.26%respectively.The effective rate of subbronchial therapy was 100% (98/98).
Conclusion
Gram-negative bacteria is more common during these two years in our hospital.Bacterias were insensitive to most antibiotics.It is effective to treat children with LRI by clinical infusion of Ambroxol Hydrochloride under bronchoscope.
2019 Vol. 26 (17): 186-189 [
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64
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190
Investigation and study on the operation of critical value system of clinical laboratory in our hospital
WU Hai-yan； WANG Qing-bo； ZHANG Bao-xiang
Objective
To understand the operation of critical value system of clinical laboratory in our hospital.
Methods
A retrospective statistical analysis was performed on 637 cases of reports of critical values detected in our hospital from January to December 2017,and targeted measures of continuous improvement were developed.
Results
The total incidence rate of reports of critical values found at the medical laboratory was 0.20%.The highest incidence rate of critical value was white blood cells(WBC),accounting for 0.59%(176/29 862),followed by creatine kinase(CK),accounting for 0.46%(103/22 561).The number of critical value reports during the day was mostly concentrated between 8:00 and 12:00 am.The number of critical values reported in the week occurred on Tuesday and Wednesday,and less on Saturday and Sunday.The composition of the critical value of the year in the top three was from March to April,accounting for 24.3%,from January to February,accounting for 21.3%and from November to December,accounting for 16.7%.According to the department ranked in order,ICU accounted for 28.7% (183/637),anorectal clinic accounted for 19.5%(124/637),and emergency department accounted for 14.0%(89/637).The critical value notification rate was≥99.8%,and the critical value notification rate of timeliness was≥98.7%.
Conclusion
The analysis and summary of the operational quality of the critical value system in our hospital not only assists in helping critical value systems objectively reflect clinical needs,but also helps clinicians improve efficiency in curing and treating patients,reducing the degree of the work intensity of other medical staff.
2019 Vol. 26 (17): 190-193转196 [
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61
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194
Study of relationship between occupational fatigue and occupational burnout in the clinical doctors
NIE Jin-wang； ZHANG Xiu-qin
Objective
To explore the relationship between occupational fatigue and occupational burnout in the clinical doctors.
Methods
A total of 110 clinical doctors in the Second People′s Hospital of Zoucheng City from October to November 2018 were selected and investigated with Chinese version of Maslach burnout inventory (MBI),Fatigue scale-14 (FS-14),and Pearson correlation analysis was used to explore the relationship between them.
Results
The emotional exhaustion score of clinical doctors was(24.35±6.28)points,which was significantly higher than that of the norm([22.19±9.53]points)(t=2.24,P＜0.01).The score of low personal achievment of clinical doctors was(31.37±4.22)points,which was more lower than that of the norm ([36.54±7.34]points)(t=5.51,P＜0.01).The total score of FS-14 was(9.36±2.42)points,among them,56 cases(50.9%)were more than 7 points.Correlation analysis showed occupational fatigue was positively correlated with emotional exhaustion,depersonification dimension(r=0.615,0.568,P＜0.01),occupational fatigue was negative correlation with low personal achievement(r=-0.573,P＜0.01).
Conclusion
There is strong correlation between occupational fatigue and occupational burnout,occupational fatigue is an influence factor of occupational burnout,To relieve occupational fatigue can gring down occupational burnout of the clinical doctors.
2019 Vol. 26 (17): 194-196 [
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67
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197
Influence of emotional management on nurses′self-confidence and professional attribution
LI Huan； WAN Li-xia； CHENG Wei
Objective
To explore the influence of emotional management on nurses′self-confidence and professional belonging.
Methods
A total of 40 female clinical nurses in our hospital from January 2016 to December 2018 were selected as the research objects,and simulation scenario,related training,psychological counseling and thematic discussion were used to intervene.The scores of self-efficacy,the rate of nursing errors and nursing complaints before and after intervention were compared.The factors leading to nurses′lack of sense of professional belonging was analyzed.
Results
Nurses′nursing errors and nursing complaints showed a downward trend through emotional management intervention.In 2016,2017,2018,the turnover rates of nurses in our hospital were 4.57%,3.73%,3.27%,respectively,and nurses′sense of occupational belonging increased.Before emotional management intervention,nurses′sense of self-efficacy score was (22.35±2.38)points,and after intervention,their sense of self-efficacy increased to (25.74±2.51)points,the difference was statistically significant(t=3.18,P＜0.01).
Conclusion
Emotional management can effectively mobilize the enthusiasm of nurses,enhance the sense of occupational belonging of nurses,reduce the incidence of errors,improve the overall quality of nursing in hospitals,and ensure medical safety and nursing safety.
2019 Vol. 26 (17): 197-199 [
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65
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200
Application effect of modern management strategy in hospital medical record statistics
YANG Liu
Objective
To improve the quality of hospital medical record statistics and explore the value of modern management strategy.
Methods
A total of 164 patients admitted to our hospital from April 2016 to April 2018 were selected as the research objects.Eighty-two patients admitted to our hospital from April 2016 to March 2017 were taken as the control group.Eighty-two patients admitted to our hospital from April 2017 to April 2018 were taken as the observation group.The modern medical record management was carried out.The patients′death,service satisfaction and medical record errors under various management modes were analyzed.
Results
The total mortality rate in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05),and the satisfaction rate in the observation group was 97.56%,which was higher than that in the control group(89.02%),the difference was statistically significant(P＜0.05).The total error rate of medical record management in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).
Conclusion
In medical record statistics,modern management can improve the quality of medical record management,and has application value.
2019 Vol. 26 (17): 200-202转206 [
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48
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203
Application effect of quality control circle activity in reducing the opening delay rate of selective first operation
GUO Hai-ling； TAN Cai-ji； CHEN Li-hong ； YANG Shu-qun； XU Bo-yuan
Objective
To investigate the application effect of quality control circle(QCC)activity in reducing the opening delay rate of selective first operation.
Methods
A total of 1766 selective first operations from January to October in 2018 were selected as the study subjects.The observation group had 183 elective first operations from October 2018,and the control group had 875 elective first operations from January to May in 2018.The control group was given the conventional management measures,and the observation group was given the QCC management method.On June 1,2018,the QCC group was established,with the activity cycle of 4 months.The activity subject was designated,the activity plan Gantt chart was developed,the status quo was investigated,the target value was set,and the true cause was verified and the proposed countermeasures and implementation were made.The opening delay rate of selective first operation,the average delay time of opening stage and the average delay time of surgeon entering the room were compared between the two groups.
Results
The opening delay rate of selective first operation in the observation group was significantly lower than that in the control group,and the difference was statistical significance (P＜0.05).The average delayed time of selective first operation and the average delayed time of entering the room of the surgeon in the observation group were significantly shorter than those in the control group,and the differences were statistical significance(P＜0.05).In the observation group,the target achievement rate was 65.25%and the improvement rate was 41.42%after QCC.
Conclusion
Carrying out QCC can effectively reduce the opening delay rate of selective first operation,which is worthy of clinical promotion.
2019 Vol. 26 (17): 203-206 [
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65
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207
Influence of early contact with father′s skin on the prevention of jaundice of newborns in natural childbirth
YANG Jin-e; LIN Cui; NING Hua-li; REN Li-rong
Objective
To explore the influence of early skin contact of father′s on the prevention of jaundice of newborns in natural childbirth.
Methods
A total of 300 newborns natural childbirth smoothly from June 2017 to July 2018 in our hospital were selected and randomly divided into the study group and the control group,150 cases in each group.The study group had skin contact with the father within 10 minutes after birth,while the newborns in the control group were placed in the capsule for 1 hour after birth,without early skin contact.The bilirubin values of 24,36,48 and 72 hours after birth were monitored.The duration of successful breast-feeding,the duration of the first sucking,the time of the first meconium excretion,crying,plantar temperature and heart rate of the two groups were observed and recorded.
Results
The incidence of jaundice in the study group was only 26.7%,which was significantly lower than that in the control group(38.7%)(P＜0.05).The duration of first sucking in the study group was longer than that in the control group,the time of the duration of successful breast-feeding,the first meconium excretion in the study group were significantly shorter than those in the control group (P＜0.05).The duration of crying in 30,60 and 120 minutes after birth in the study group was significantly shorter than that in the control group,the heart rate in the study group was lower than that in the control group,and the plantar temperature in the study group was higher than that in the control group (P＜0.05).
Conclusion
The implementation of father′s early contact is helpful to the prevention of jaundice of newborns in natural childbirth.
2019 Vol. 26 (17): 207-210 [
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51
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Application value of comprehensive nursing in the treatment of patients with schizophrenia
WANG Dan; LI Yan-li; CUI Qian; Lin Bo-wen
Objective
To study the application value of comprehensive nursing in the treatment of patients with schizophrenia.
Methods
The 46 cases of schizophrenia treated in Municipal Bureau of Civil Affairs Mental Hospital of Guangzhou City from June 2015 to February 2017 were collected as subjects.They were divided into the general group and the comprehensive group according to the random number table method,each group consisted of 23 cases.The general group took routine nursing intervention.Comprehensive nursing intervention was adopted in the comprehensive group.The concomitant mental scale scores,quality of life scores,total scores of positive and negative symptom scales,treatment adherence,schizophrenia disease cognition,and hospitalization time were compared between the two groups.
Results
The total compliance of the general group was higher than that of the conventional group,and the difference was statistically significant(P＜0.05).The cognitive score of patients in the comprehensive group was higher than that in the general group,and the hospital stay was shorter than the general group,the differences were statistically significant(P＜0.05).There were no significant differences in the concise mental scale score,quality of life score,and total score of positive and negative symptom scales between the two groups before treatment(P＞0.05).The concise mental scale score,total score of positive and negative symptom scales of patients in the comprehensive group after the nursing were lower than those of the general group,and the quality of life score was higher than that of the general group,and the differences were statistically significant(P＜0.05).
Conclusion
The comprehensive application of comprehensive nursing in the treatment of schizophrenia patients can improve the patients'disease cognition and treatment compliance,improve clinical symptoms,improve the quality of life,shorten the length of hospital stay,and it is worthy of promotion and application.
2019 Vol. 26 (17): 211-213 [
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65
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Application effect comparison of family members involved in nursing intervention and routine nursing in patients with multiple metatarsal fractures
ZHENG Yi-hong; LIANG Yi-rong; HUANG Su-ming; LIN Cai-zhen
Objective
To investigate the clinical value of family members involved in nursing intervention and routine nursing in the treatment and rehabilitation of patients with multiple metatarsal fractures.
Methods
Sixty patients with multiple metatarsal fractures from January 2016 to June 2017 were enrolled as subjects in the department of outpatient in our hospital.The patients were divided into observation group and control group by the random number table method,with 30 cases in each group.In the control group,routine nursing was used,while in the observation group,the family members involved in the nursing intervention was adopted.The outpatient treatment,rehabilitation and nursing satisfaction of the two groups were compared.
Results
After treatment,the outpatient cost of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the self-rating anxiety scale (SAS)scores between the two groups before treatment(P＞0.05).After treatment,the SAS scores of the two group were lower than those before treatment,and the SAS scores of the observation group were lower than the control group with statistical significance (P＜0.05).Half-year follow-up showed that the external fixation dismantling time and fracture healing time of the observation group were shorter than those of the control group.The excellent and good rate of foot functional recovery was superior to that of the control group with a significant difference(P＜0.05).The total nursing satisfaction of the observation group(93.33%)was higher than that of the control group(73.33%),the difference was statistically significant(P＜0.05).
Conclusion
Family members of patients with multiple metatarsal fractures involved in nursing intervention can effectively improve the treatment of patients,facilitate the improvement of rehabilitation and nursing satisfaction,and has good economic benefit.
2019 Vol. 26 (17): 214-216 [
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61
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Application value of health education in maintenance hemodialysis patients
ZHENG Fen; RUAN Yu-yun
Objective
To explore the application effect of health education in maintenance hemodialysis (MHD)patients.
Methods
A total of 92 patients who underwent regular dialysis from January 2017 to January 2018 in hemodialysis center of our hospital were selected as the subjects,and divided into observation group and control group by random number table method,with 46 cases in each group.The control group received routine dialysis and life guidance during dialysis,and the observation group received special health education,6 months for a cycle.The albumin(Alb),hemoglobin(Hb),creatinine(SCr),urea nitrogen(BUN),blood potassium(K
+
)level between the two groups before and after intervention were compared,and the patients′psychosocial quality of life (MCS),physiologically relevant quality of life(PCS),and kidney-dialysis-related quality of life(KDTA)were scored using the KDQOL-SF1.3 scale.
Results
Compared with pre-intervention,the levels of Alb and Hb were significantly increased in the observation group after intervention,and the levels of SCr,BUN and K
+
were significantly lower(P＜0.05).The levels of Alb and Hb were higher than those of the control group,and the levels of SCr,BUN and K
+
were lower than those of the control group (P＜0.05).Compared with the pre-intervention,the MCS,PCS and KDTA scores of the observation group were significantly increased (P＜0.05).The MCS,PCS and KDTA scores of the observation group were higher than those of the control group after intervention,the differences were statistically significant(P＜0.05).
Conclusion
Health education in patients with MHD can improve various physiological indicators and improve the quality of life.It is worth learning.
2019 Vol. 26 (17): 217-219 [
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54
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Application effect of chest pain center reperfusion process nursing in patients with acute myocardial infarction
XIE Li-fen; ZHANG Wei-tai; QIU Xia-ling
Objective
To explore the nursing effect of chest pain center reperfusion process nursing in patients with acute myocardial infarction.
Methods
A total of 61 patients with acute myocardial infarction who received percutaneous coronary intervention(PCI)from October 2017 to October 2018 were selected as the subjects,and randomly divided into control group(n=30)and observation group(n=31).Patients in control group received routine nursing,while patients in observation group received chest pain center reperfusion process nursing.The time from the first medical contact to the first electrocardiogram(FMC2ECG),the time from the first ECG to the diagnosis of acute myocardial infarction,the time from the first medical contact to the double antiplatelet therapy and the average time from the beginning of thrombolytic therapy (D2N),the hospital-to-balloon dilatation time,hospitalization time and hospitalization cost of patients were compared between the two groups.
Results
The FMC2ECG,from the first ECG to the diagnosis,dual antiplatelet therapy time from first medical contact,D2N and the time from consultation to the completion of the operation in the observation group were significantly shorter than those in the control group (P＜0.05).The hospitalization time and hospitalization time from admission to balloon dilation in the observation group were significantly shorter than those in the control group,and the hospitalization cost was significantly less than that in the control group (P＜0.05).
Conclusion
Chest pain center reperfusion process nursing has a good application effect in the nursing of acute myocardial infarction.It can effectively shorten the treatment process,reduce hospitalization costs.
2019 Vol. 26 (17): 220-222 [
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Application effect of comfortable nursing intervention in the nursing of patients with appendicitis surgery
XIANG Liu; YE Li-qin
Objective
To study the application effect of comfortable nursing intervention in the nursing of patients with appendicitis surgery.
Methods
A total of 129 patients with appendicitis who were admitted to our hospital from January to December 2018 were selected as the subjects,and randomly divided into the control group (n=65)and the experimental group (n=64).Patients in the control group underwent conventional nursing.The patients in the experimental group underwent conventional nursing combined with comfort nursing.The complications,surgical data and nursing satisfaction of the two groups were compared.
Results
The total incidence of complications in the experimental group was lower than that of the control group,and the difference was statistically significant(P＜0.05).The total satisfaction of nursing was higher than that of the control group,and the difference was statistically significant(P＜0.05).The operation time and hospitalization time of the experimental group were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group,and the differences were statistically significant(P＜0.05).
Conclusion
The implementation of comfortable nursing intervention for patients with appendicitis surgery can control the patients′subsequent complications to a certain extent,and can significantly improve the patients′satisfaction with the nursing.It is worthy of promotion and application in subsequent clinical practice.
2019 Vol. 26 (17): 223-225 [
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Clinical effect of prospective nursing in the gastrointestinal decompression
YE Miao-qin; LUI Li-Mei
Objective
To explore the clinical effect of the prospective nursing in the gastrointestinal decompression.
Methods
A total of 80 patients with intestinal obstruction treated by gastrointestinal decompression from April 2017 to April 2018 in Department of Gastroin Testinal Surgery of our hospital were selected as the study subjects,and they were randomly divided into the control group and the observation group,40 cases in each group.The control group was adopted the conventional nursing care,and the observation group was adopted prospective nursing.The clinical effect in two groups were compared.
Results
The success rate of primary catheterization in the observation group was(85.0%),which was higher than that of control group (50.0%),with significant difference (P＜0.05).The degree of total satisfaction in the observation group was 100%,which was higher than that of the control group (75.0%),with significant difference (P＜0.05).The total incidence of nursing complications in the observation group was 22.5%,which was significantly lower than 57.5%in the control group,the difference was statistically significant(P＜0.05).
Conclusion
The clinical effect of the prospective nursing in the gastrointestinal decompression for intestinal obstruction patients can reduce the nursing risks and improve the satisfaction degree.
2019 Vol. 26 (17): 226-228 [
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Effect of liquid dressing Sanyrene in the prevention of incontinence-associated dermatitis in critically ill patients
YANG Rui-hong
Objective
To investigate the effect of liquid dressing Sanyrene in the prevention of incontinence-associated dermatitis(IAD)in critically ill patients.
Methods
A total of 100 critically ill patients with IAD who were admitted to our hospital from September 2017 to December 2018 were selected and randomly divided into the control group and the observation group according to their admission ID number,50 cases in each group.The control group was washed with warm water after defecation,while the observation group was treated with liquid dressing,skin-spraying and rubbing by liquid dressing Sanyrene on the basis of the control group.The clinical effect,the degree of skin lesion,the incidence of IAD and the occurrence time of IAD were compared between the two groups.
Results
The total effective rate of the observation group(98%)was significantly higher than that of the control group(74%),there was a significant difference(χ
2
=11.960,P=0.005).The incidence of skin lesion in the observation group was significantly lower than that in the control group,and the difference between the two groups was statistically significant(χ
2
=18.918,P=0.001).The incidence of IAD in the observation group(8.00%)was significantly lower than that in the control group(30.00%),the difference between the two groups was statistically significant(P＜0.05).The occurrence time of IAD in the observation group was(3.13±0.77)d,which was significantly shorter than(9.43±1.94)d in the control group,the difference between the two groups was statistically significant(P＜0.05).
Conclusion
The liquid dressing Sanyrene is effective in preventing incontinence dermatitis in critically ill patients.It can effectively prevent perianal skin injury caused by defecation incontinence and improve the quality of life of patients.It is worthy of clinical application and promotion.
2019 Vol. 26 (17): 229-231 [
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Influence of perioperative quality nursing on the rehabilitation effect of children with inguinal hernia
GE Wei-hua; YANG Yang; WEI Ben-li; SHI Qi
Objective
To explore the influence of perioperative quality nursing on the rehabilitation effect of children with inguinal hernia.
Methods
A total of 82 children with inguinal hernia who received surgical treatment in Hongqi Hospital Affiliated to Mudanjiang Medical College from February 2017 to July 2018 were selected as research objects.According to the serial number of the operation,the children with single number were included in the control group,and the children with double number were included in the observation group,41 cases in each group.The children of the control group were given conventional nursing methods,the children of the observation group were given perioperative quality nursing intervention.After the completion of the nursing work,the nursing effect was evaluated from several aspects including the time of getting out of bed,the length of stay in hospital,the incidence of postoperative complications and the cost of surgical treatment.
Results
The time of getting out of bed and the length of stay in hospital in the observation group were shorter than those in the control group,the total incidence of postoperative complications of the observation group was lower than that of the control group,and the cost of surgical treatment of the observation group was lower than that of the control group,the differences were statistically significant(P＜0.05).
Conclusion
Perioperative quality nursing intervention for children with inguinal hernia can effectively improved the rehabilitation effect of children.
2019 Vol. 26 (17): 232-234 [
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235
Application effect of seamless nursing model in patients with acute kidney injury complicated with acute respiratory distress syndrome caused by septic shock in ICU
ZHAO Jing
Objective
To explore the application value of seamless nursing mode in patients with acute renal injury complicated with acute respiratory distress syndrome (ARDS)caused by septic shock in ICU.
Methods
A total of 56 patients with acute renal injury complicated with ARDS who were admitted to the ICU admitted to our hospital from December 2016 to December 2018 were divided into the observation group and the control group according to the random number table method,28 patients in each group.The control group received routine nursing,and the observation group was given seamless nursing model.The serum C-reactive protein (CRP)level,anxiety self-rating scale (SAS score),self-rating depression scale(SDS score),the total degree of satisfaction with nursing,and nursing stress scores of nursing staff were compared between the two groups.
Results
After nursing,the CRP levels of the two groups were lower than those before nursing(P＜0.05),and the serum CRP level of the observation group after nursing was lower than that of the control group(P＜0.05).After the nursing,the SAS score and SDS score of the observation group were lower than the control group(P＜0.05).After nursing,the total degree of satisfaction with nursing of the observation group was significantly higher than that of the control group (P＜0.05).The nursing pressure of the nursing staff in the observation group was lighter than that in the control group,and the difference was statistically significant(P＜0.05).
Conclusion
Patients in ICU with acute kidney injury complicated with ARDS caused by septic shock with seamless nursing can alleviate the disease,reduce the degree of anxiety and depression of patients,improve patients′satisfaction with nursing work,and reduce the work pressure of nursing staff.It deserves clinical promotion.
2019 Vol. 26 (17): 235-237转241 [
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62
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Application effect of comprehensive nursing intervention in improving expectant treatment of placenta previa
LU Jin-wen
Objective
To explore the application effect of comprehensive nursing intervention in improving the expectant treatment of placenta previa.
Methods
A total of 98 cases of expectant pregnant women with placenta previa treated in our hospital from February 2017 to February 2018 were selected as the research objects.According to the random number table method,they were divided into observation group(49 cases)and control group （49 cases）.The control group was given routine nursing intervention,while the observation group was given comprehensive nursing intervention.Pregnancy outcomes and maternal and infant status were compared between the two groups.
Results
The termination time of pregnancy in the observation group was(36.9±3.0)weeks,which was higher than that in the control group of([33.2±3.1]weeks),the difference was statistically significant(P＜0.05）;the amount of postpartum hemorrhage in the observation group was([406.2±40.2]ml),less than that in the control group of([465.9±50.3]ml),the difference was significant(P＜0.05）;the puerperal infection rate in the observation group was 2.0%,lower than that in the control group (10.2%).There was statistical significance(P＜0.05）;the Apgar score of observation group was(9.5±0.4)points,higher than that of control group([8.0±0.2]points),with statistical significance(P＜0.05）;the weight of observation group was(3.9±0.8)kg,higher than that in the control group([3.0±0.2]kg),with statistical significance(P＜0.05）;the abnormal rate of fetal position of observation group was 2.00%,and the rate of respiratory distress was 2.00%,both of which were lower than those of the control group (10.2%and 8.2%),had significant differences(P＜0.05）;there was no significant difference in perinatal mortality between the two groups(P＞0.05）;the overall satisfaction of the observation group was 97.9%,higher than 81.6%of the control group,with significant difference(P＜0.05）.
Conclusion
Nursing intervention has a significant effect in the clinical application of expectant placenta previa therapy,which is worthy of clinical promotion.
2019 Vol. 26 (17): 238-241 [
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65
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Effect of whole-course Doula accompanying delivery on delivery quality and outcome
CHEN Yan-fen; WU Chun-xiu; WEI Lu-hua; PENG Yu
Objective
To investigate the effect of whole-course Doula accompanying delivery on the delivery quality and outcome.
Methods
Altogether 120 pregnant women who hospitalized in our hospital from January 2017 to April 2018 and is giving birth were selected as the research objects and divided into routine delivery group(60 cases)and Doula delivery group(60 cases)according to randon number table method.The regular delivery group was used routine delivery mode;while the Doula delivery group adopted the whole-process Doula accompanying delivery mode.The duration of labor,the amount of hemorrhage during delivery,the mode of delivery,satisfaction degree and incidence of neonatal complications were compared between the two groups.
Results
The first and second stages of labor in Doula delivery group were significantly shorter than those in routine delivery group;the amount of hemorrhage during delivery was significantly less than that of routine delivery group(P＜0.05）.The natural delivery rate and satisfaction degree of the parturients in Doula delivery group were significantly higher than those in routine delivery group,and the incidence of neonatal complications was significantly lower than that in routine delivery group,with statistically significant difference (P＜0.05）.
Conclusion
Doula accompanying delivery can effectively shorten the birth process and improve the natural delivery rate of parturients as well as the quality of life of newborns,which ensures the safety of mothers and infants.
2019 Vol. 26 (17): 242-244 [
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62
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Effect of smoking cessation intervention in patients with chronic obstructive pulmonary disease
RAN Liu; ZHANG Qin; ZHANG Yuan
Objective
To study the effect of smoking cessation intervention in patients with chronic obstructive pulmonary disease(COPD).
Methods
A total of 100 patients with COPD admitted to our hospital from February 2016 to February 2017 were selected as the research objects.According to the computer random method,they were divided into observation group and control group,50 cases in each group.The observation group was given smoking cessation intervention,while the control group was given routine intervention.The pulmonary function index,quality of life and total satisfaction of intervention were compared.
Results
The alveolar capillary bed volume(Vc)([86.32±1.54]%),maximum ventilation volume(MVV)([80.32±1.02]L/min),forced vital capacity(FVC)([2.98±1.02]L)and forced expiratory volume(FEV
1
)([1.98±0.32]L)in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05）.The symptoms score （[30.12±1.02]points）,activity score([50.21±1.34]points)and the effect of disease on life score([60.14±1.54]points)of patients with chronic obstructive pulmonary disease in the observation group were lower than those in the control group(P＜0.05）.The total satisfaction rate in the observation group was 98.00%,higher than that in the control group,the difference was statistically significant(P＜0.05）.
Conclusion
Smoking cessation intervention can significantly improve the prognosis of patients with COPDe,which is worth studying.
2019 Vol. 26 (17): 245-247 [
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50
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Effect of 24 h rehabilitation nursing on hemiplegic nerve and limb function with ischemic stroke
WU Li-hua
Objective
To investigate the effect of 24 h rehabilitation nursing on hemiplegic nerve and limb function with ischemic stroke （CIS).
Methods
A total of 80 cases with CIS hemiplegia admitted in our hospital from August 2017 to August 2018 were selected and divided into the control group and the observation group according to random number table method,40 cases in each group.The control group were received routine nursing,the observation group were implemented ultra-early rehabilitation nursing,the intervention of the vital signs within 24 hours after disease,the living habits with the two groups after intervention,the adverse psychological status of the two groups after intervention,and the interventions were compared.Pre-and post-neural function European stroke score (ESS)and changes in life quality of Barthel index were used.
Results
After intervention,the total proportion of adverse psychological conditions such as anxiety and depression in the observation group were lower than control group(P<0.05）.The neurological ESS score in the observation group was higher than that of the control group(P<0.05）.The modified Barthel index was higher than that of the control group(P<0.05）.
Conclusion
The implementation of ultra-early(24 hour)rehabilitation nursing intervention for patients with CIS has positive effects to improve patients′psychological status and promote neurological recovery and improve life quality.
2019 Vol. 26 (17): 248-250 [
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Application effect of problem tracking nursing in patients with hematopoietic stem cell transplantation
JIAN Li; LI Hai-rong; LI Hong-wei; LIN Hai-ling; HUANG Mei-di; SU Shu-juan; WANG Yu; GUO Zi-wen
Objective
To explore the application effect of problem-tracking nursing in patients with hematopoietic stem cell transplantation.
Methods
A total of 82 patients who underwent hematopoietic stem cell transplantation in our hospital from March 2015 to April 2018 were selected and they were divided into the control group(n=41)and observation group (n=41)using a randomized grouping method.Routine nursing intervention and problem-tracking nursing were performed in the control group and observation group respectively.The total incidence of adverse reactions and nursing satisfaction degree were compared between the two groups.The self-rating anxiety scale(SAS)and the self-rating depression scale(SDS)were used to evaluate the negative emotional changes before and after treatment in the two groups.
Results
There was no significant difference in SAS or SDS score between the two groups before nursing(P＞0.05).The SAS and SDS scores of the two groups after nursing were lower than those of the same group before nursing with statistical significance (P＜0.05).The scores of SAS and SDS after nursing intervention in the observation group were lower than those of the control group (P＜0.05).The total incidence of adverse reactions was 7.32%in the observation group,which was lower than that in the control group accounting for 26.83%with a significant difference (P＜0.05).The total satisfaction degree of nursing in the observation group was 95.12%,which was higher than that in the control group accounting for 78.05%with a significant difference(P＜0.05).
Conclusion
The implementation of problem tracking nursing intervention can effectively improve the bad emotion of patients during hematopoietic stem cell transplantation,avoid the risk of adverse reactions,increase the nursing satisfaction,and have a positive impact on the prognosis improvement.Therefore,it can be promoted and applied in clinic.
2019 Vol. 26 (17): 251-253 [
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