中西医结合治疗糖尿病周围神经病变的效果及对血清同型半胱氨酸和胱抑素C水平的影响

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Abstract Objective To explore the effect of integrated traditional Chinese and western medicine on diabetic peripheral neuropathy(DPN)patients and levels of homocysteine(Hcy)and cystatin-C(Cys-C)in serum.Methods A total of 124 DPN patients in our hospital from October 2015 to June 2018were selected and randomly divided into experimental group and control group,62 cases in each group.On the basis of basic drug treatment,the patients in control group were given 500 μg Mecobalamin Injection once a day.The experimental group was treated with Huangqi Xuanshen Decoction on the basis of the control group.After two courses of treatment,toronto clinical score(TCSS),sensory nerve conduction velocity(SNCV),motor nerve conduction velocity(MNCV)and levels of HCY and Cys-C were compared between the two groups,in order to evaluate the therapeutic effect of traditional western medicine basic treatment plus Huangqi Xuanshen Decoction on diabetic peripheral neuropathy.Results After two courses of treatment,the total effective rate of the experimental group was higher than that of the control group(P<0.05）;the TCS score of the experimental group was lower than that of the control group(P<0.05）;the NCV and SNCV of the experimental group were higher than those of the control group(P<0.05）;the levels of HCY and Cys-C of the experimental group were lower than those of the control group,and the differences were statistically significant(P<0.05）.Conclusion The combination of traditional Chinese medicine and western medicine has a significant effect on DPN patients.Moreover,this therapy can significantly reduce the levels of HCY and Cys-C in serum.

Key words： Integrated traditional Chinese and western medicine Diabetes mellitus Peripheral neuropathy

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	ZENG Li-sheng
	OUYANG Chun-xi

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ZENG Li-sheng,OUYANG Chun-xi. Effect of integrated traditional Chinese and western medicine on diabetic peripheral neuropathy and its influence on serum levels of homocysteine and cystatin-C[J]. 中国当代医药, 2019, 26(17): 151-153转156.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I17/151

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