丙泊酚联合七氟醚麻醉对小儿腹腔镜疝囊高位结扎术血流动力学及麻醉趋势指数的影响

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Abstract Objective To investigate the effect of Propofol combined with Sevoflurane anesthesia on hemodynamics and narcotrend index(NI)of laparoscopic high ligation of hernia sac in children.Methods Ninety-nine children who underwent laparoscopic high ligation of hernia sac in our hospital from March 2015 to March 2016 were selected as the research objects.They were divided into group A,group B and group C according to the random sampling method,33 cases in each group.The group A received single Propofol anesthesia,the group B received single Sevoflurane anesthesia,while the group C received Propofol combined with Sevoflurane anesthesia.The NI,heart rate(HR),mean arterial pressure (MAP),and oxygen saturation (SpO2)before and after surgery were compared in the three groups.The total incidence rate of adverse reactions in the three groups of children was counted.Results There was no significant difference in NI among the three groups before surgery (P＞0.05).The NI of the three groups after surgery was lower than that before surgery,and the difference was statistically significant(P＜0.05).The NI of group C after surgery was higher than that of group A and group B,and the differences were statistically significant(P＜0.05).There was no significant difference in the NI between group A and group B after surgery(P＞0.05).There were no significant differences in HR,MAP and SpO2among the three groups before surgery(P＞0.05).The HR after surgery in the three groups was lower than that before surgery,the MAP and SpO2were higher than those before surgery,and the differences were statistically significant (P＜0.05).The HR of group C after surgery was higher than that of group A and group B,the MAP and SpO2were lower than those of group A and group B,and the differences were statistically significant(P＜0.05).There were no significant differences in the HR,MAP and SpO2 between group A and group B after surgery(P＞0.05).The total incidence rate of adverse reactions in group C was lower than that in group A and group B,and the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence rate of adverse reactions between group A and group B(P＞0.05).Conclusion Clinically,the combined anesthesia of Propofol and Sevoflurane can stabilize hemodynamics in children undergoing laparoscopic high ligation of hernia sac.

Key words： Narcotrend index Hemodynamics Laparoscopic high ligation of hernia sac Sevoflurane Propofol

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	Articles by authors
	ZHANG Ling
	YIN Zheng-chun
	YE Zhu-ying
	FU Shui-qing
	LIU Zhen-ming

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ZHANG Ling,YIN Zheng-chun,YE Zhu-ying, et al. Effect of Propofol combined with Sevoflurane anesthesia on hemodynamics and narcotrend index of laparoscopic high ligation of hernia sac in children[J]. 中国当代医药, 2019, 26(17): 133-136.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I17/133

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