奥卡西平联合氟哌噻吨美利曲辛片治疗原发性三叉神经痛患者的临床效果

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Abstract Objective To explore the clinical effect of Oxcarbazepine combined with Flupentixol and Melitracen Tablets in the treatment of patients with primary trigeminal neuralgia(PTN).Methods A total of 68 PTN patients treated in our hospital from October 2016 to October 2018 were selected and divided into the study group (n=34)and the control group (n=34)according to random number table method.Patients in the control group were given Oxcarbazepine,and those in the study group were given Oxcarbazepine combined with Flupentixol and Melitracen Tablets.Both groups were treated for 3 months.The clinical effects,the incidence of adverse reactions,and the scores of visual analogne scale(VAS)and Pittsburgh sleep quality index scale(PSQI)before treatment and 1 month and 3 months after treatment were compared between the two groups.Results After 3 months of treatment,the overall effective rate of the study group was 94.12%(32/34),which was higher than 73.53%(25/34)of the control group(P＜0.05).There was no significant difference in the VAS and PSQI scores between the two groups before treatment(P＞0.05),and both scores were reduced in both groups at 1 and 3 months after treatment,and those in the study group were lower than those in the control group (P＜0.05).The total incidence of adverse reactions in the study group was 17.65%,and there was no significant difference between the experimental group and the control group (8.82%)(P＞0.05).Conclusion Oxcarbazepine combined with Flupentixol and Melitracen Tablets can improve the clinical effect in the treatment of patients with primary trigeminal neuralgia,relieve the pain of patients,improve the sleeping quality,and have high safety.

Key words： Primary trigeminal neuralgia Oxcarbazepine Flupentixol and Melitracen Tablets Pain degree Sleeping quality

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	CHEN Rui

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CHEN Rui. Clinical effect of Oxcarbazepine combined with Flupentixol and Melitracen Tablets in the treatment of patients with primary trigeminal neuralgia[J]. 中国当代医药, 2019, 26(17): 137-139转144.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I17/137

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