中国当代医药

中国当代医药

Home

中文

中国当代医药

Forthcoming Articles

Advanced Search

Download Articles

Quick Search


2021 Vol. 28, No. 2 Published: 2021-01-18

	4	Research on prediction model of ethnic minority health service utilization in Guizhou Province based on artificial neural network
		DU Wei1；LIU Chan-chan2；LI Duan1 ；HU Jia-qi1；FAN Xing-ying1；ZHOU Han-ni1；CHANG Yue1▲
		Objective To study the influence of the health literacy on health service utilization among ethnic minorities in Guizhou Province by a method of constructing artificial neural network model,making the prediction of health service utilization intelligent.Methods From June to December 2019,1031 resident ethnic minorities aged 15 to 69 years old in Guizhou Province were selected by multistage sampling for a questionnaire survey.Univariate analysis was used to screen the variables,and multivariate analysis was performed by an artificial neural network model.Results Among the 1031 minority samples,the outpatient service utilization rate was 7.08%,and the inpatient service utilization rate was 8.44%.There were no statistically significant differences in different individual basic information,total score of health literacy and scores of each category between outpatient utilization group and outpatient non-utilization group(P＞0.05).There were statistically significant differences in the occupation,the total score of health literacy,and scores of health information literacy and safety and first aid literacy between the inpatient non-utilization group and the inpatient utilization group,the differences were statistically significant(P＜0.05).Then occupation(P=0.025),health information literacy(P=0.025),safety and first aid literacy(P=0.000)were selected as input layer nodes,and an artificial neural network inpatient service utilization prediction model was constructed.Based on the model,155 sets of data were used for verification.All the absolute value of errors did not exceed 1,with the maximum near 0,so the model fitting effect was good.Conclusion Occupation,health information literacy,safety and first aid literacy significantly affect the utilization of inpatient service for ethnic minorities in Guizhou Province.The artificial neural network model is highly accurate and can be used for further prediction of health service utilization.
		2021 Vol. 28 (2): 4-8 [Abstract] ( 52 ) HTML (30 KB) PDF (0 KB) ( 10 )

	9	Orthogonal test method and SPSS data analysis to optimize the forming process of Xuanzhi Granules
		CHEN Ji-ying；WU Mou；PENG Zhan-peng
		Objective To study the forming process of Xuanzhi Granules.Methods Orthogonal test was used to optimize the key factors affecting the formation of Xuanzhi Granules,taking the forming rate,moisture absorption rate and angle of repose as indicators,multi-index weight comprehensive score was used to optimize the forming process.Results The best forming process:the volume fraction of ethanol was 95%,the ratio of the amount of concentrated liquid(g)to the amount of dextrin(g)was 1∶1.3,and the ratio of the amount of concentrated liquid(g)to the amount of lubricant(mL)was 1∶0.2.Conclusion This process has high repeatability,simple and easy control,high feasibility,and excellent product quality,which is conducive to the actual production of Xuanzhi Granules.
		2021 Vol. 28 (2): 9-11转36 [Abstract] ( 65 ) HTML (20 KB) PDF (0 KB) ( 7 )

	12	Exploration on the functional mechanism of naringin based on network pharmacology
		CHEN De-yan
		Objective To explore the functional mechanism of naringin based on network pharmacology.Methods The Traditional Chinese Medicine Systems Pharmacology Database(TCMSP)was used to obtain naringin absorption,distribution,metabolism,and excretion properties evaluation,and target protein and genes of naringin were identified by GeneCards,and then were filtered out by Uniprot to select overlapping targets and genes.The analysis was performed through GeneMANIA database and Molecule Annotation System 3.0(MAS 3.0),including gene ontology(GO)enrichment and KEGG pathway analysis,and finally a visual network diagram was constructed through Cytoscape.Results Naringin had good druggability,and 14 putative protein targets were identified.Through enrichment analysis result,naringin mainly directly regulated bone metabolism through Wnt signaling pathways,TGF-β signaling pathway,MAPK signaling pathways and osteoclast differentiation signaling pathway,while through the P13K-Akt and VEGF signaling pathways affected bone metabolism indirectly to play the role of anti-osteoporosis.Its anti-cancer mechanism was mainly through influencing the endocrine inhibitory signaling pathway and the proteoglycan in cancer pathway.The anti-inflammatory and anti-oxidant mechanism was mainly through the intervention of MAPK signal pathway and TOLLlike receptor signaling pathway,etc.Conclusion The functional mechanism of naringin shows the characteristics of multiple targets.It plays a role in anti-cancer,regulating bone metabolism,anti-inflammatory and antioxidant process.The comprehensive application of network pharmacology can help to predict the pharmacological mechanism of compound quickly and comprehensively,and provide guidance for further experimental verification.
		2021 Vol. 28 (2): 12-17 [Abstract] ( 54 ) HTML (33 KB) PDF (0 KB) ( 7 )

	18	Determination of glutamine content in Glutamine Capsules by high performance liquid chromatography tandem mass spectrometry

		Objective To establish a method for the determination of glutamine in Glutamine Capsules by ultra-high performance liquid chromatography tandem mass spectrometry.Methods An ultra-high performance liquid chromatography tandem mass spectrometer was used.The column was Atiantis T3(1100 mm×2 mm,3 μm),and the column temperature was 38℃.The mobile phase was 0.1% formic acid solution∶acetonitrile,and flow rate was 0.30 mL/min.The content of glutamine in Glutamine Capsules was determined by multi reaction monitoring mode.Results The linear relationship of glutamine was good in the range,linear regression equation Y=4×10-6X+0.1336,RSD was 2.2%～4.8%,and the detection limit of glutamine was 9.8 ng/mL.Conclusion The method is simple,specific,accurate and sensitive,and can be used for the determination of glutamine in medicine and biological samples.
		2021 Vol. 28 (2): 18-21 [Abstract] ( 41 ) HTML (25 KB) PDF (0 KB) ( 6 )

	22	Influence of platelet transfusion times and preventive medication before platelet transfusion on the incidence of blood transfusion reactions
		SHEN Jia-kun DONG Hui-juan ZHENG Lin LI Chun-yan YAN Jing-xiu
		Objective To study the influence of platelet transfusion times and preventive medication before platelet transfusion on the incidence of blood transfusion reactions.Methods The incidence of blood transfusion reactions after platelet transfusion in 170 patients in the Department of Hematology,Shangrao People′s Hospital from February 2017 to August 2018 was investigated,they were divided into M1 group(＜5 times),M2 group(5-9 times)and M3 group(≥10 times)according to the number of platelet transfusions of the same patient,according to the history of transfusion reactions,they were divided into group with history of transfusion reactions and group without history of transfusion reactions,the influence of different blood transfusion times and preventive medication on the incidence of blood transfusion reactions was analyzed.Results A total of 784 cases of platelet transfusions were performed in 170 patients with hematologic diseases requiring platelet transfusion,there were 61 transfusion reactions,the incidence of transfusion reactions was 7.8%.There was statistically significant difference in the incidence of transfusion reactions among patients in the M1,M2,and M3 groups(P＜0.05).There was no statistically significant difference in the incidence of blood transfusion reactions in the three groups of M1,M2 and M3 with and without preventive medication(P＞0.05).There was statistically significant difference in the incidence of transfusion reactions between the group without history of transfusion reactions and the group with history of transfusion reactions(P＜0.05).There was no statistically significant difference in the incidence of blood transfusion reaction in the case of preventive medication and no preventive medication in the group with or without history of transfusion reactions(P＞0.05).Conclusion The more times of blood transfusion,the more patients with adverse reactions of blood transfusion.The incidence of blood transfusion reactions in patients with history of blood transfusion reaction is higher than that in patients without history of blood transfusion reaction.Preventive medication has no effect on the incidence of blood transfusion reactions in patients with multiple blood transfusions and those with a history of blood transfusion reactions.
		2021 Vol. 28 (2): 22-25 [Abstract] ( 47 ) HTML (27 KB) PDF (0 KB) ( 6 )

	26	Research progress of miR-212 on the regulation of diseases gene expression
		LONG Fu-li； PENG Zi-ming； FENG Feng； LIN Yong； ZHANG Jian-ling； QIN Yan-xin； MAO De-wen；WEI Ai-ling
		miRNA is a kind of RNA molecules existing in plants and animals.Each of them can regulate one or several genes,possessing a very complex regulation network.According to the research so far,miRNA regulates one-third of human genes at least.miR-212 is a newly discovered miRNA,its expression plays a very important role in the occurrence and development of human diseases.It has great potential research value in explaining the pathogenesis of related diseases,screening diagnostic markers,treating diseases,developing new drugs and predicting disease prognosis.This paper reviews the effect of miR-212 in cancer,cardiovascular disease,neurodegenerative disease and other diseases for clinical reference.
		2021 Vol. 28 (2): 26-29 [Abstract] ( 54 ) HTML (28 KB) PDF (0 KB) ( 6 )

	30	Research progress of therapeutic drugs for psoriasis
		WEI Yi-ying； LI Shi-meng； WEI Wen-guo；ZHOU Hong-gang
		Psoriasis is a chronic inflammatory skin disease which is caused by a variety of factors and easy to attack repeatedly.It has a long course and is difficult to cure.It can also induce various complications,including psoriatic arthritis,cardiovascular disease,metabolic syndrome and obesity,which seriously affect the quality of life of patients.In recent years,with in-depth research on the pathogenesis of psoriasis,many drugs that can effectively treat psoriasis have been developed,among which the research on psoriasis targeted therapeutic drugs has made great progress.This paper reviews the marketed compounds and clinical compounds of psoriasis.
		2021 Vol. 28 (2): 30-36 [Abstract] ( 62 ) HTML (34 KB) PDF (0 KB) ( 9 )

	37	Clinical effect of low molecular weight heparin in the treatment of fetal growth restriction
		ZHANG Chen XIE Xiao-xia XIAO Yu-hong
		Objective To study the effect of low molecular weight heparin(LMWH)in the treatment of fetal growth restriction(FGR).Methods A total of Fifty pregnant women with FGR who were diagnosed and treated in Shenzhen Luohu District of Maternal and Child Health Hospital fromJuly 2016 and August 2017 were selected as the research subjects.They were divided into control group and study group by the random number table method,25 cases in each group.The control group was given conventional treatment,and the the study group was given conventional treatment and treatment with LMWH.Fetal growth,umbilical blood flow and adverse reactions were observed in both groups.Results The increased values of maternal fundal height,abdominal circumference,and fetal growth in study group were higher than those in control group,the differences were statistically significant(P＜0.05).Differences in fetal pulsatility index(PI）,resistance index(RI)or umbilical artery systolic and diastolic blood flow velocity ratio(S/D))between the two groups were not statistically significant before treatment(P＞0.05).After treatment,the PI,RI and S/D in both groups were lower than those of the control group,PI,RI and S/D in study group were lower than those in the control group after treatment,the differences were statistically significant(P＜0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups(P＞0.05).Conclusion Treatment with LMWH for FGR can effectively improve fetal umbilical artery blood flow and promote fetal growth and development.However,due to the particularity of pregnant women,it is necessary to strengthen nursing during medication to ensure the curative effect and safety.
		2021 Vol. 28 (2): 37-39 [Abstract] ( 55 ) HTML (23 KB) PDF (0 KB) ( 8 )

	40	Diagnostic analysis of the detection of serum prealbumin level in disease activity of gout
		QIAN Jiang1；LIU Xiao-chun；YE Shui-ying； XIE Yan-qing
		Objective To explore the diagnostic value of the detection of serum prealbumin(PA)level in the disease activity of gout.Methods The clinical data of 88 patients with gout who treated in the hospital from January 2017 to December 2019 were retrospectively analyzed.They were divided into intermission group(30 cases)and acute attack group(58 cases)according to different clinical symptoms,and 30 healthy people with physical examination during the same period were selected as control group.The levels of PA level,blood uric acid(UA),erythrocyte sedimentation rate(ESR)level and high-sensitivity C-reactive protein(hs-CRP)level were compared among the three groups,the correlation of PA level with UA,ESR and HS-CRP in patients with gout was analyzed.Results The level of PA in the acute attack group and the intermission group were lower than that in the control group,and the levels of UA,ESR and hs-CRP were higher than those in the control group,the differences were statistically significant(P＜0.05).The level of PA in the acute attack group was lower than that in the intermission group,the levels of ESR,hs-CRP were higher than those in the intermission group,the differences were statistically significant(P＜0.05).There was no statistical difference in the level of UA between the acute attack group and the intermission group(P＞0.05).The PA level of patients with gout was negatively correlated with ESR and hs-CRP level(r=-0.351,-0.472，P=0.001,0.000),There was no significant correlation between PA level and UA level(P＞0.05).Conclusion PA,UA,ESR,and hs-CRP of gout patients in different periods are significantly different,and PA levels are negatively correlated with ESR and hs-CRP levels.PA levels can be used as auxiliary indicators for judging gout disease activity.
		2021 Vol. 28 (2): 40-42转46 [Abstract] ( 51 ) HTML (24 KB) PDF (0 KB) ( 7 )

	43	Clinical effect of low dose Glucocorticoid combined with Theophylline in treating bronchial asthma
		CHEN Xiao-yun；TANG Xiao-xiao
		Objective To explore the clinical effect of low-dose glucocorticoid(GC)combined with Theophylline in the treatment of bronchial asthma.Methods A total of 80 cases with bronchial asthma admitted in Zhongshan Hospital of Affiliated to Dalian University from April 2018 to April 2019 were selected and divided into observation group and control group,40 cases in each group.The observation group was treated with inhaled beclomethasone dipropionate 250 μg/ twice a day combined with oral sustained-release Theophylline,while the control group was treated with inhaled beclomethasone dipropionate 500 μg/ twice a day.After one course of treatment,the changes of inflammatory indicators were compared between the two groups.The results of asthma control test were the changes of standard(ACT)scores during treatment.The recurrence and hospitalization due to acute asthma attack,and the occurrence of adverse reactions during treatment was compared between the two groups.Results The levels of tumor necrosis factor-α(TNFα)and high-sensitivity C-reactive protein(hs-CRP)in the inflammatory indexes of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).The ACT score of the observation group was higher than that of the control group at the same time,the difference was statistically significant(P＜0.05).One week after treatment and one month after treatment.the total proportion of skin pruritus,water and sodium retention,abnormal blood glucose and so on in the observation group during treatment were lower than those of the control group,the differences were statistically significant(P＜0.05).After one year of follow-up,the recurrence and hospitalization times due to acute asthma attack in the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).Conclusion For bronchial asthma,theophylline combined with lowdose GC can effectively reduce inflammatory reaction and improve clinical symptoms with few adverse reactions,which is of great significance for reducing acute attack of asthma.
		2021 Vol. 28 (2): 43-46 [Abstract] ( 44 ) HTML (24 KB) PDF (0 KB) ( 7 )

	47	Application value of noninvasive positive pressure ventilation in emergency treatment of acute respiratory failure
		KE Wei-guang CHEN Zhen-rong
		Objective To explore the application value of non-invasive positive pressure ventilation(NIPPV)in the emergency treatment of acute respiratory failure.Methods From December 2017 to December 2019,116 patients with acute respiratory failure admitted to Maoming People′s Hospital in Guangdong Province were selected and divided into control group and experimental group according to random number table method,58 cases in each group.Patients in the control group were given conventional symptomatic supportive therapy,and patients in the experimental group were given NIPPV on basic of the control group.The clinical effect,clinical mortality,incidence of ventilator pneumonia,and various indicators of patients before and after treatment were compared between the two groups.Results The total treatment efficiency of the experimental group was 93.10%,which was higher than 74.14% of the control group,and the difference was statistically significant(P＜0.05).The mortality and the incidence of ventilator pneumonia in the experimental group were 1.72% and 6.90%,respectively.Compared with 13.79% and 25.86% of the control group,the differences were statistically significant(P＜0.05).After treatment,the partial oxygen pressure(PaO2)and blood pH were(79.89±10.98)mmHg and（7.35±0.03）in the experimental group,which were higher than those in the control group of(63.61±7.95)mmHg and(7.26±0.03),and the differences were statistically significant(P＜0.05).Carbon dioxide partial pressure(PaCO2),heart rate(HR),and respiratory rate(RR)levels in the experimental group were(44.45±4.19)mmHg,(21.66±6.19)times/min,and(101.34±21.58)times/min,which were lower than those in the control group of(58.47±6.31)mmHg,(26.53±8.69)times/min,and(113.88±21.72)times/min,the differences were statistically significant(P＜0.05).Conclusion The application of in the emergency treatment of acute respiratory failure can reduce the incidence of death and complications,effectively improve the patients′ indicators,alleviate the patients′ symptoms,and has significant curative effect.
		2021 Vol. 28 (2): 47-49 [Abstract] ( 43 ) HTML (21 KB) PDF (0 KB) ( 6 )

	50	Effect of electroacupuncture combined with modern rehabilitation technology on rehabilitation of patients with bladder urinary incontinence caused by spinal cord injury
		KE Hua-jing；ZHANG Yu； WANG Yu-xiang
		Objective To explore the effect of electroacupuncture combined with modern rehabilitation technology on rehabilitation of patients with spinal cord injury neurogenic bladder incontinence.Methods A total of 84 patients with neurogenic bladder incontinence of spinal cord injury who were admitted to the First People′s Hospital of Jiujiang City,Jiangxi Province from October 2017 to October 2019 were selected and divided into two groups with random number table method,42 cases in each group.The control group was treated with modern rehabilitation technology,and the study group was treated with electroacupuncture combined with modern rehabilitation technology for 8 weeks.The urinary recovery time,urodynamic indicators and urination were compared between the two groups.Results The first urination time and the establishment of reflex urination time in the study group were(6.77±2.69)d and(9.79±3.21)d,which were shorter than those in the control group of(8.4±23.15)d and(13.02±4.86)d,the differences were statistically significant(P＜0.05).The maximum urinary flow rate and maximum urination volume in the study group after treatment were(14.15±3.89)mL/s,(196.64±39.22)mL,which were higher than those in the control group of(11.86±3.67)mL/s and(179.39±35.27)mL,and the residual urine volume and urination frequency were(80.25±27.17)mL,(12.18±3.65)times/d,which were less than(94.13±29.24)mL and(14.43±3.54)times/d of the control group,the differences were statistically significant(P＜0.05).Conclusion Electroacupuncture combined with modern rehabilitation technology has a significant effect on neurogenic bladder urinary incontinence caused by spinal cord injury,which can help establish urination reflex,improve upper urinary tract function and urination ability.
		2021 Vol. 28 (2): 50-52 [Abstract] ( 44 ) HTML (22 KB) PDF (0 KB) ( 6 )

	53	Short-term effect of fast track surgery for laparoscopic radical resection of colorectal cancer
		GAO Ye； LI Feng-yan； WANG En-ci
		Objective To observe the short-term effect of fast track surgery(FTS)in laparoscopic radical resection of colorectal cancer(Miles).Methods A total of 80 patients with colorectal cancer in Chaoyang Second Hospital,Liaoning Province from January 2017 to January 2019 were selected and divided into the control group(n=40)and the observation group(n=40)by random number table method.The control group was treated with conventional surgical rehabilitation intervention.The observation group was treated with FTS rehabilitation intervention on the basis of the control group.The short-term effect of the two groups were arnpared.Results The first time of getting out of bed,defecating,exhausting,hospitalization and eating in the observation group were shorter than those in the control group,the differences were statistically significant(P＜0.05).The levels of interleukin-6(IL-6)and tumor necrosis factors-α(TNF-α)in the two groups were higher than those before operation,and the observation group was lower than that of the control group,the differences were statistically significant(P ＜0.05).The World Health Organization quality of life scale(WHOQOL-BREF)scores of the two groups 3 months after operation were higher than those before operation,and the observation group was higher than that of the control group,the differences were statistically significant(P＜0.05).Conclusion The application of FTS in Miles patients with significant short-term effect,can significantly shorten the recovery time of patients,help patients quickly discharged from hospital,is an effective concept of rehabilitation nursing.
		2021 Vol. 28 (2): 53-55 [Abstract] ( 41 ) HTML (22 KB) PDF (0 KB) ( 7 )

	56	Clinical effect of early plastic surgery on deep burns of hands
		CAO Qing；DING Yu-wei
		Objective To explore the clinical effect of early plastic surgery on deep burns of hands.Methods A total of 96 patients with deep hand burns admitted to Jiujiang First People′s Hospital,Jiangxi Province from September 2017 to February 2020 were selected as the research subjects.The clinical data of the patients were retrospectively analyzed,and they were divided into reference group(n=48)and study group(n=48)according to different treatment methods.Patients in the reference group were treated with delayed repair,and in the study group was used early plastic surgery The treatment effect,complication rate and patient satisfaction with treatment were compared between the two groups.Results The overall response rate of treatment in the study group was 95.83%,higher than that of the reference group accounting for 83.33%,and the difference was statistically significant(P＜0.05).The total incidence of complications in the study group was 6.25%，lower than that of the reference group accounting for 20.83%,and the difference was statistically significant(P＜0.05).The total treatment satisfaction of the study group was 91.67%,higher than that of the reference group accounting for 77.08%,and the difference was statistically significant(P＜0.05).Conclusion Early plastic surgery is effective in treating patients with deep hand burns,which can effectively reduce the incidence of complications and improve patient satisfaction.
		2021 Vol. 28 (2): 56-58 [Abstract] ( 47 ) HTML (22 KB) PDF (0 KB) ( 7 )

	59	Clinical effect of Tacrolimus cream in the treatment of eczema and its effect on TNF-α and IFN-γ levels
		SONG Guo-qiang
		Objective To explore the effect of Tacrolimus cream on eczema.Methods A total of 100 patients of eczema admitted to Shenyang Seventh People′s Hospital from January 2018 to November 2019 were selected as the research objects,they were divided into the control group(50 cases)and the observation group(50 cases)according to the random number table method.The control group received conventional treatment,and the observation group received Tacrolimus cream on the basis of the control group.Treatment effect,secondary infection,symptom improvement time,treatment satisfaction,and changes in tumor necrosis factor-α(TNF-α)and interferon-γ(IFN-γ)levels before and after treatment were compared between two groups.Results The total effective rate and total satisfaction of treatment in the observation group were higher than those in the control group,the incidence of secondary infection was lower than that in the control group,the improvement time of symptoms was shorter than that in the control group,the differences were statistically significant(P＜0.05).After treatment,the levels of TNF-α and IFN-γ were higher than those in the control group,the differences were statistically significant(P＜0.05).Conclusion The treatment effect of Tacrolimus cream in eczema patients is significant,which can effectively reduce the incidence of secondary infection,reduce inflammation,promote physical recovery of patients,and improve patients′ satisfaction with treatment.It is worthy of popularization and application.
		2021 Vol. 28 (2): 59-61 [Abstract] ( 51 ) HTML (20 KB) PDF (0 KB) ( 5 )

	62	Comparison of clinical effect of transsphincteric fistula ligation and fistula resection on anorectal fistula
		GAO Gui-yun；MI Yuan-yuan；SUN Qi-ming
		Objective To analyze the effect of transsphincteric fistula ligation and fistula resection on anorectal fistula.Methods A total of 106 patients with anorectal fistula admitted to Liaoyang City Central Hospital from October 2016 to October 2019 were selected as the research subjects.According to the double-blind principle(before grouping,patients and researchers were not aware of the grouping status and the treatment received.),they were divided into two groups.The normal group(53 cases)was treated with fistula resection,and the research group(53 cases)was treated with transsphincter fistula ligation,and the clinical effects of the two groups were observed.Results The comparison of pain severity and anal function scores between the two groups before operation,the differences were not statistically significant(P＞0.05).At 30 days after operation,both groups had lower pain and anal function scores than before operation,the differences were statistically significant(P＜0.05).At 30 days after operation,the pain and anal function score in the research group were lower than that of the normal group,the differences were statistically significant(P＜0.05).The total incidence of postoperative complications in the research group was lower than that in the normal group,the difference was statistically significant(P＜0.05).Conclusion Transsphincteric fistula ligation and fistula resection are effective in the treatment of anorectal fistula with simple operation and few complications,and can also rapidly improve the anal function of patients and relieve pain.
		2021 Vol. 28 (2): 62-64 [Abstract] ( 54 ) HTML (22 KB) PDF (0 KB) ( 7 )

	65	Clinical effect of Amitriptyline combined with Venlafaxine in the treatment of postpartum depression
		XIE Guang-ping
		Objective To investigate the clinical effect of Amitriptyline combined with Venlafaxine in the treatment of postpartum depression and its influence on the Hamilton depression scale(HAMD)score.Methods Retrospective analysis was made on the data of 116 pregnant women with postpartum depression admitted to the Third People′s Hospital of Ganzhou City from May 2017 to May 2019.According to different treatment methods,the pregnant women were divided into control group and observation group,with 58 cases in each group.The control group was treated with Venlafaxine only,while the observation group was treated with Amitriptyline combined with Venlafaxine.HAMD scores of the two groups were compared before treatment and at 2,4 and 6 weeks after treatment.The therapeutic effect of the two groups were compared.The total incidence of adverse reactions after treatment was compared between the two groups.Results At 2,4,and 6 weeks of treatment,the HAMD scores of the observation group([21.34±5.31],[15.60±6.67],[11.46±5.93]points)were lower than those of the control group([25.33±5.62],[20.42±6.49],[17.25±6.13]points),and the differences were statistically significant(t=13.344,17.672,21.493,P＜0.05).At 2,4 and 6 weeks of treatment,HAMD scores of both groups were lower than those before treatment,with statistically significant differences(P＜0.05).The total effective rate in the observation group(96.55%)was higher than that in the control group(79.31%),and the difference was statistically significant(χ2=8.123,P＜0.05).The incidence rates of adverse reactions(dizziness,insomnia,headache and nausea)in the observation group were not significantly different from those in the control group(P＞0.05).Conclusion The combination of Amitriptyline and Venlafaxine in the treatment of postpartum depression has a higher effective rate,and the incidence of adverse reactions is not significantly different from that of Venlafaxine alone.Therefore,the effect of combination of Amitriptyline and Venlafaxine is better than that of Venlafaxine alone in the treatment of postpartum depression.
		2021 Vol. 28 (2): 65-67转80 [Abstract] ( 47 ) HTML (23 KB) PDF (0 KB) ( 7 )

	68	Correlation analysis of serum Chemerin,Adropin levels with type 2 diabetes combined with hyperhomocysteinemia
		LIANG Bi-；RUAN Shi-chong； LIN Zhong-jun； TAN Guo-ju；CHEN Shi-yong
		Objective To explore the correlation between serum Chemerin and Adropin levels and type 2 diabetes(T2DM)combined with hyperhomocysteinemia(Hhcy).Methods A total of 168 patients with T2DM admitted to People′s Hospital of Yangjiang from April 2016 to April 2018 were selected as the research objects.According to Hhcy combined or not,they were divided into 81 cases in the simple T2DM group and 87 cases in the T2DM+Hhcy group.50 healthy people who underwent physical examination at the same time were selected as the control group.The basic data and biochemical indicators between the groups were compared,and Pearson correlation analysis was performed.Results The body mass index(BMI),systolic blood pressure(SBP),diastolic blood pressure(DBP),total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),fasting plasma glucose(FPG),HemoglobinA1c(HbA1c),homocysteine(Hcy),Chemerin of T2DM+Hhcy group and T2DM group were higher than those of control group;the HDL-C and Adropin of T2DM+Hhcy group and T2DM group were lower than those of control group,and the differences were statistically significant(P＜0.05).The course of disease in T2DM+Hhcy group was longer than that in T2DM group,the BMI,TG,LDL-C,FPG,HbAlc,Hcy,Chemerin in T2DM+Hhcy group were higher than those in T2DM group,and the differences were statistically significant(P＜0.05).After Pearson correlation analysis,the course of disease,BMI,LDL-C,FPG,HbA1c,Chemerin were positively correlated with Hcy in T2DM patients,and Adropin was negatively correlated with it(P＜0.05).Conclusion Chemerin and Adropin may both participate in the pathological process of Hhcy in T2DM patients.
		2021 Vol. 28 (2): 68-70 [Abstract] ( 51 ) HTML (22 KB) PDF (0 KB) ( 7 )

	71	Influence of premixed insulin and insulin pump on the clinical effect and the time of reaching the standard of blood glucose in patients with diabetes
		WANG Ming
		Objective To investigate the influence of premixed insulin and insulin pump on the clinical effect and the time to reach the blood glucose standard in patients with diabetes.Methods A total of 136 patients with diabetes who were admitted to the Endocrinology Department of Iron and Coal General Hospital of Liaoning Health Industry Group from December 2018 to October 2019 were selected as the research subjects.According to the different methods of administration,divided the patients into control group and study group ,with 68 cases in each group.The control group was treated with Insulin Aspart 30 and the study group was treated with insulin pump Insulin Aspart.The clinical effect and the time to reach the blood glucose standard were compared between the two groups.Results There was no significant difference in fasting blood glucose before treatment and 2 h postprandial blood glucose between the two groups(P＞0.05).Half a month after treatment,fasting blood glucose and 2 h postprandial blood glucose in the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05),and the fasting blood glucose and 2 h postprandial blood glucose in the study group were lower than those in the control group(P＜0.05).The time of reaching the standard of blood glucose was shorter than that in the control group,and the dosage of insulin in the study group was less than that in the control group,the differences were statistically significant(P＜0.05).The cost of insulin in the study group was lower than that in the control group,but the total cost of consumables was higher than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Insulin pump infusion of Insulin Aspart in the treatment of diabetic patients,can reduce the use of insulin under the condition of better blood glucose control effect,this way is worth recommending.
		2021 Vol. 28 (2): 71-73 [Abstract] ( 50 ) HTML (22 KB) PDF (0 KB) ( 6 )

	74	Clinical study on the application of the periosteum stripper to pry open intertrochanteric fractures with proximal and forward displacement by spiral blade incision
		LIU Xiang ；LI Xi-ping； JIANG Ping-pin；GUO Jian-bo
		Objective To explore the effect of the periosteum stripper on the difficult intertrochanteric fracture of femur with proximal and forward displacement by means of a spiral blade incision.Methods A total of 60 cases of refractory intertrochanteric fracture with proximal displacement of fracture in Xinyu Hospital of Traditional Chinese Medicine from January 2018 to January 2020 were selected and randomly divided into control group(30 cases)and observation group(30 cases)by single and even number method.The control group was treated with PFNA internal fixation after closed traction reduction by traction bed,and the observation group was treated with PFNA after periosteal stripper through spiral blade incision prying reduction methods of internal fixation.The operation time,intraoperative blood loss,postoperative function,joint range of motion,pain score and complication rate were compared between the two groups.Results There were no significant differences in operation time and intraoperative blood loss between the two groups(P>0.05).There were no significant differences in postoperative function,range of motion and pain between the two groups(P>0.05).There was no significant difference in the total complication rate between the two groups(P>0.05).Conclusion Using periosteal stripper through spiral blade incision prying is a good surgical idea.It can achieve ideal therapeutic effect for patients with refractory intertrochanteric fracture whose proximal fracture moves forward,and has clinical application value.
		2021 Vol. 28 (2): 74-76 [Abstract] ( 39 ) HTML (21 KB) PDF (0 KB) ( 6 )

	77	Early closed reduction combined with Herbert screw,Kirschner wire and mini suture anchors in the treatment of periosteal fracture and dislocation
		ZHANG Chuan-hui；SUN Cheng-shuai
		Objective To investigate the clinical effect of early closed reduction combined with Herbert screw,Kirschner wire and anchor screw for the perilunate fracture and dislocation.Methods The clinical data of 37 patients with fresh perilunate fracture and dislocation in Chaoyang Center Hospital from January 2014 to may 2019 were retrospective analyzed.They were divided into the observation group(23 cases)and the control group(14 cases)according to the treatment method.In the observation group,closed reduction of fracture and dislocation in the early stage,all the fractures were fixed with hollow compression screw and/or Kirschner wire,and the mini suture anchors were performed to repair intercarpal ligament in a limited incision while the intercarpal joints were temporarily fixed with Kirschner wire.In the control group,patients were treated with closed reduction and Kirschner wire internal fixation and plaster cast external fixation.The differences of wrist function,wrist flexion and extension range of motion,fracture healing,complication（re-dislocation,nonunion and osteonecrosis）were compared between the two groups.Results The Cooney wrist function scores in the observation group was higher than that in control group,the difference was statistically significant(P＜0.05).The healing time of fracture in observation group was shorter than that in control group,the difference was statistically significant(P＜0.05).The range of wrist flexion and extension was larger than that in control group,the difference was statistically significant(P＜0.05).And the total incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion Early closed reduction combined with Herbert screw,Kirschner wire and repair of intercarpal ligament with mini suture anchors is a good treatment for fresh periosteal fracture and dislocation.It can effectively promote fracture healing,reduce the occurrence of complications,enable patients to obtain good wrist joint function,and prevent the occurrence of wrist instability.
		2021 Vol. 28 (2): 77-80 [Abstract] ( 47 ) HTML (38 KB) PDF (0 KB) ( 6 )

	81	Clinical effect of anatomical locking plate in treatment of comminuted olecranon fracture
		ZHANG Chao
		Objective To explore the clinical effect of anatomical locking plate in the treatment of comminuted olecranon fractures.Methods A total of 82 patients with ulnar olecranon comminuted fractures admitted to Liaoyang Liaohua Hospital from January 2017 to December 2018 were selected as the research subjects,and they were divided into the control group and the observation group according to random number table method,with 41 cases in each group.The control group was treated with an olecranon dissection plate.The group was treated with anatomical locking plate,and the operation-related indexes,fracture healing time,elbow recovery effect and postoperative complications were compared between the two groups.Results There were no significant differences between the two groups in intraoperative bleeding,operation time and fracture healing time(P ＞0.05).The postoperative elbow joint function recovery rate(95.12%)of the observation group was higher than that of the control group(78.05%),the difference was statistically significant(P＜0.05).The postoperative complication rate of patients in the observation group(4.88%)was lower than that of the control group(17.07%),the difference was statistically significant(P＜0.05).Conclusion Satisfaction of psychology for medical students is generally high.Optimizing the curriculum,integrating the faculty,enriching the teaching and assessment methods,and adjusting the teaching materials may have positive effect on improvement of the quality of psychological education in clinical medical students.
		2021 Vol. 28 (2): 81-83转90 [Abstract] ( 38 ) HTML (33 KB) PDF (0 KB) ( 6 )

	84	Clinical study on painless induced abortion in early pregnancy with scar uterus under ultrasound guidance
		MA Jun-min； PENG Liang； XU Sheng
		Objective To explore the clinical effect of ultrasound-guided painless artificial abortion in early pregnancy of scar uterus.Methods A total of 90 cases of early pregnancy patients with scar uterus who admitted to Yingtan Maternal and Child Health Hospital,Jiangxi Province from August 2018 to August 2019 were selected as the research objects and randomly divided into the research group and the control group according to the blind selection method,with 45 cases in each group.The research group used ultrasound guided painless artificial abortion,and the control group used conventional painless artificial abortion.The operation time,intraoperative blood loss,total incidence of postoperative complications and the rate of secondary sterilization postoperative were compared between the two groups.Results The operation time of the study group was shorter than that of the control group,the intraoperative blood loss was less than that of the control group,and the differences were statistically significant(P＜0.05).The total incidence of postoperative complications in the study group was 4.44%,which was lower than 17.77% in the control group,and the difference was statistically significant(P＜0.05).The rate of secondary sterilization postoperative in the study group was 2.22%,which was lower than 15.55% in the control group,and the difference was statistically significant(P＜0.05).Conclusion Ultrasound-guided painless artificial abortion is a simple,safe and effective operation method,which is worthy of active promotion and application in clinical practice.
		2021 Vol. 28 (2): 84-86 [Abstract] ( 44 ) HTML (33 KB) PDF (0 KB) ( 7 )

	87	Effect of the time interval between premature rupture of fetal membranes and delivery on maternal and infant outcomes
		WANG Jia
		Objective To explore the effect of the time interval between premature rupture of fetal membranes and delivery on maternal and infant outcomes.Methods The clinical data of 442 cases of full-term premature rupture of membranes in Xingcheng Women and Children′s Hospital from June 2015 to June 2019 were retrospectively analyzed and divided into group A(＜12 h,259 cases),group B(12-60 h,132 cases)and group C(＞60 h,51 cases)according to the time from rupture to delivery.The delivery methods and maternal and infant outcomes were compared among the three groups.Results There were no statistically significant differences in blood loss 24 h after delivery and length of postpartum hospital stay among the three groups(P＞0.05).The rate of cesarean section in group C was higher than those in groups A and B,and the differences were statistically significant(P＜0.05).The incidence of chorioamnionitis in group C was higher than those in groups A and B,and the differences were statistically significant(P＜0.05).The incidence of chorioamnionitis in group B was higher than that in group A,and the difference was statistically significant(P＜0.05).The incidence of intrauterine distress and the hospitalization rate of newborns in group C was higher than those of groups A and B,and the differences were statistically significant(P＜0.05).Conclusion The shorter the time from premature rupture to delivery,the better the outcome.The longer the time from premature rupture to delivery,the higher the incidence of newborn complications.In order to improve the prognosis of mothers and newborns,it is suggested that those with premature rupture of membranes at term should be actively admitted to hospital for induction of labor,and the time interval between rupture and delivery should be shortened as far as possible.
		2021 Vol. 28 (2): 87-90 [Abstract] ( 50 ) HTML (33 KB) PDF (0 KB) ( 8 )

	91	Effect comparison of Mifepristone and Tripraline in the treatment of uterine fibroid
		WANG Xiao-shuang
		Objective To compare the effect of Mifepristone and Tripraline in the treatment of uterine fibroid.Methods A total of 60 patients with uterine fibroid who treated in Department of Gynaecology in Shenyang Women′s and Children′s Hospital from January to June in 2019 were selected as the research objects and divided into the observation group and the control group by random number table method,with 30 cases in each group.The observation group was treated with Mifepristone and the control group was treated with Tripraline.The treatment effect,fibroid volume,serum hormone and hemoglobin level and adverse reactions were compared between the two groups.Results The effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,the fibroid volumes of the two groups were smaller than those before treatment,and the differences were statistically significant(P＜0.05).After treatment,the fibroid volume of the observation group was smaller than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,the levels of estradiol(E2)and follicle-stimulating hormone(FSH)in the two groups were lower than those before treatment,the level of hemoglobin was higher than that before treatment,and the differences were statistically significant(P＜0.05).After treatment,the levels of E2 and FSH in the observation group were lower than those in the control group,the level of hemoglobin was higher than that in the control group,and the differences were statistically significant(P＜0.05).The total rate of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Mifepristone can significantly reduce the volume of uterine fibroids,reduce the levels of E2 and FSH,increase the level of hemoglobin,and the adverse reactions were less,with more significant clinical efficacy.
		2021 Vol. 28 (2): 91-93转97 [Abstract] ( 64 ) HTML (35 KB) PDF (0 KB) ( 6 )

	94	Influence of different suture methods of the lower uterus on the scar thickness and complications of the lower uterus in re-pregnant women
		YU Xiao-chuan
		Objective To investigate the effects of different suture methods of the lower uterus on the scar thickness and complications of the lower uterus in re-pregnant women.Methods The clinical data of 86 pregnant women who were pregnant again after cesarean section in Dalian Maternal and Child Health Hospital from May 2017 to May 2019 were retrospectively analyzed.All women underwent cesarean section at the first time of delivery and were divided into group A(66 cases,double uterine suture)and group B(20 cases,single uterine suture)according to different suture methods during cesarean section.The clinical indicators,pelvic adhesion degree and complications of the two groups were compared.Results The operation time of the first cesarean section in group A was shorter than that in group B,and the difference was statistically significant(P＜0.05).There was no statistically significant difference in blood loss of the first cesarean section in group A and group B(P＞0.05).The scar thickness of the lower uterine in group A was greater than that in group B during the re-pregnancy,and the difference was statistically significant(P＜0.05).The degree of pelvic adhesion during the second cesarean section in group A was lower than that in group B,and the difference was statistically significant(P＜0.05).The total incidence of complications during the second cesarean section in group A was lower than that in group B,and the difference was statistically significant(P＜0.05).Conclusion To compare with the single uterine suture,the operation time of the double uterine suture is shorter,the blood loss is similar,the scar thickness of the lower uterine is thicker,the degree of pelvic adhesion is lower,and the total incidence of complications is lower.
		2021 Vol. 28 (2): 94-97 [Abstract] ( 43 ) HTML (34 KB) PDF (0 KB) ( 6 )

	98	Clinical effect of postural change combined with manual fetal head rotation in correcting persistent occipitoposterior position
		YANG Mei；ZHENG Lan-lin； HE Hui-ai；LYU Bo
		Objective To explore the clinical effect of postural change combined with manual fetal head rotation in correcting persistent occipitoposterior position.Methods From August 2018 to January 2019,a total of 180 cases of persistent posterior occipital parturients who gave birth in Changsha Central Hospital of Hu′nan Province were selected as the subjects.90 parturients with persistent occipitoposterior position who underwent manual fetal head transfer intervention during labor from August to October 2018 were included as the control group,and 90 parturients with persistent occipitoposterior position who underwent combined body position change and manual fetal head transfer from November 2018 to January 2019 were included as the observation group,the time and the success rate of reduction in the first and second stages of labor between the two groups were compared.Results The duration of the first and second stages of labor in the observation group were shorter than those in the control group,the differences were statistically significant(P＜0.05);the success rate of reduction in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).Conclusion In the process of persistent occipitoposterior dystocia,the method of postural change combined with manual fetal head transfer has advantages over the traditional manual fetal head transfer method in terms of labor duration and success rate,which is an effective measure to correct persistent occipitoposterior position and reduce the incidence of cephalic dystocia,and can be popularized and applied in clinical practice.
		2021 Vol. 28 (2): 98-100 [Abstract] ( 33 ) HTML (33 KB) PDF (0 KB) ( 7 )

	101	Effect of Atropine Sulfate Eye Drops on visual sensitivity and stereoscopic function of teenage patients with refractive errors
		DENG En-li
		Objective To investigate the effect of Atropine Sulfate Eye Drops on visual sensitivity and stereoscopic function in teenage patients with refractive errors.Methods A total of 88 adolescent patients(126 eyes)with refractive errors admitted to Dalian Maternal and Child Health Care Hospital from June 2017 to June 2019 were selected as study subjects.According to the random number method,they were divided into the control group with 44 cases(62 eyes)and the observation group with 44 cases(64 eyes).The control group was treated with conventional symptomatic,and the observation group was treated with Atropine Sulfate Eye Drops.The visual acuity,stereoscopic function,diopter,intraocular pressure and axial length were compared between the two groups.Results After 3 months of treatment,the visual contrast sevsitivity,diopter and intraocular pressure of the observation group were all higher than those of the control group,the axial length was longer than that of the control group,correction amplitude and correction separation range were larger than those in the control group,and the corrected acute stereoscopic angle was smaller than that in the control group,the difference were statistically significant(P＜0.05).Conclusion Atropine Sulfate Eye Drops can significantly improve the visual sensitivity and stereoscopic function of adolescent patients with refractive errors,and can control the refractive power,intraocular pressure and axial length of patients with refractive errors,which is worthy of popularization and application.
		2021 Vol. 28 (2): 101-103转106 [Abstract] ( 57 ) HTML (33 KB) PDF (0 KB) ( 7 )

	104	Application effect of micro-screw implant anchorage technique in orthodontic treatment of elderly oral restoration
		MA Liang
		Objective To explore the application effect of micro-screw implant anchorage technique in orthodontic treatment of the elderly.Methods A total of 100 elderly patients in need of oral prosthesis in Iron Coal General Hospital of Liaoning Health Industry Group from January 2018 to December 2019 were selected as the research objects,and they were divide into a study group(50 cases)and a control group(50 cases)according to the random number table method.The two groups were treated with different prosthodontics and orthodontics,the control group received the repair method of segmental arch,and the study group received the technique of microscrew implant anchorage technique.Clinical efficacy,symptom disappearance time,pain-free time after eating,quality of life score and satisfaction were compared between the two groups.Results The total effective rate of treatment in the study group was 96.0%,which was higher than that in the control group(76.0%),the difference was statistically significant(P＜0.05).The time of disappearance of oral symptoms and pain-free time after eating were shorter in the study group than those in the control group,the differences were statistically significant(P＜0.05).The quality of life score and degree of satisfaction were higher in the study group than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Oral prosthetic orthodontic therapy has a good clinical effect on elderly patients with oral diseases.The patients have a higher quality of life score and a higher satisfaction level.The appearance score and function score of the patients are significantly improved.It is worthy of widespread clinical promotion.
		2021 Vol. 28 (2): 104-106 [Abstract] ( 47 ) HTML (30 KB) PDF (0 KB) ( 6 )

	107	Clinical effect of pulp angiogenesis in the treatment of young permanent teeth
		CHEN Ming；YU Peng
		Objective To investigate the clinical effect of pulp angiogenesis in the treatment of young permanent teeth.Methods A total of 80 young patients with permanent teeth admitted to Fushun Stomatological Hospital from August 2017 to May 2019 were selected as the study subjects.According to the random number table method,they were divided into the control group and the observation group,with 40 patients in each group.The control group was treated with root tip induced angioplasty,and the observation group was treated with pulp angiogenesis.The pain degree before and after treatment and the total therapeutic effectiveness were compared between the two groups.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the visual analogue scale(VAS)score in the observation group was lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion The application of pulp angiogenesis therapy in the treatment of young permanent teeth has a significant effect,which can effectively reduce the degree of pain after treatment and improve the quality of life of patients.
		2021 Vol. 28 (2): 107-109 [Abstract] ( 37 ) HTML (33 KB) PDF (0 KB) ( 9 )

	110	Clinical effect of Triamcinolone nasal spray combined with Desloratadine in the treatment of allergic rhinitis
		ZHOU Gui-feng
		Objective To investigate the clinical effect of Triamcinolone nasal spray combined with Desloratadine in the treatment of allergic rhinitis.Methods A total of 122 patients with allergic rhinitis who admitted to Anshan Changda Hospital from December 2018 to December 2019 were selected as the research subjects,they were divided into the control group and the study group according to the random number table method,with 61 patients in each group.The control group received Desloratadine alone,while the study group received Triamcinolone nasal spray on the basis of the control group.The clinical efficacy,the levels of interleukin-4(IL-4)and interleukin-10(IL-10)and the improvement of symptoms were compared between the two groups.Results The total clinical effective rate of the study group(91.80%)was higher than that of the control group(78.69%),the difference was statistically significant(P＜0.05).The levels of IL-4 and IL-10 in the study group were lower than those in the control group,the differences were statistically significant(P＜0.05).The scores of nasal congestion,runny nose and other symptoms in the study group were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Triamcinolone nasal spray combined with Desloratadine in the treatment of allergic rhinitis can effectively improve the patient's inflammation,promote the clinical effect,has a higher application value.
		2021 Vol. 28 (2): 110-112 [Abstract] ( 49 ) HTML (32 KB) PDF (0 KB) ( 7 )

	113	Application effect of postoperative accelerated rehabilitation strategy in patients undergoing weight reduction surgery under general anesthesia
		HE Qi-tao；TAI Yong-xiang；XU Jin-xiong；LIAO Zhi-da
		Objective To explore the application effect of postoperative accelerated rehabilitation strategy in patients undergoing weight reduction surgery under general anesthesia.Methods A total of 72 patients who received weight reduction surgery in Xiaolan People′s Hospital of Zhongshan from December 2016 to December 2019 were selected as the research subjects.According to the random number table method,the patients divided into the control group(36 cases)and the observation group(36 cases).The control group was given routine perioperative nursing,and the observation group was given accelerated postoperative rehabilitation strategy.The operation time,hospitalization time,hospitalization expenses and the incidence of ICU return after operation were compared between the two groups.Results The operation time of the observation group was shorter than that of the control group,the difference was statistically significant(P＜0.05).The hospitalization time of the observation group was shorter than that of the control group,the difference was statistically significant(P＜0.05).The hospitalization expenses of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).The incidence of ICU return after operation in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion The accelerated rehabilitation strategy is very beneficial to the recovery of the patients after weight reduction surgery under general anesthesia,which reduces the operation time and hospitalization time,and reduces the cost of hospitalization,and better promotes the rapid rehabilitation of patients.
		2021 Vol. 28 (2): 113-115 [Abstract] ( 43 ) HTML (32 KB) PDF (0 KB) ( 6 )

	116	Application of ultrasound-guided continuous saphenous nerve block plus multi-mode analgesia during knee replacement
		YUAN Zhuo-min；JIA Xin-lian；LIU Yue
		Objective To study the application of ultrasound-guided continuous saphenous nerve block plus multimode analgesia during knee replacement.Methods A total of 50 patients with knee replacement admitted to CITIC Huizhou Hospital from June 2018 to June 2019 were selected as the research objects.According to random number table method,they were divided into the control group and the research group,with 25 cases in each group.The control group received the continuous saphenous nerve block,and the research group received the continuous saphenous nerve block and multi-mode analgesia.Analgesia usage,Hospital for special surgery(HSS),Berg Balance Scale(BBS),Bruggrmann Comfort Scale(BCS)and Generic Quality of Life Inventory-74(GQOL-74)scores were observed in the two groups.Results Comparison of Cis-atracurium and Diclofenac Sodium dosage between two groups,the differences were not statistically significant(P＞0.05).The dosage of Remifentanil and Sevoflurane in the research group were higher than that in the control group,the differences were statistically significant(P＜0.05).Before surgery,HSS and BBS scores between groups showed no statistically significant differences(P＞0.05).The HHS and BBS scores of the research group were higher than those of the control group 30 days after operation,and the HHS and BBS scores of the two groups 30 days after operation were higher than those before operation,the differences were statistically significant(P＜0.05).The ambulation time and hospitalization time in the research group were shorter than those of control group,the walk distance was longer than that of control group,the BCS score of the research group was higher than that of the control group at 4 and 8 hours after operation,the differences were statistically significant(P＜0.05).There was no significant difference in GQOL-74 score between the two groups before operation before surgery(P＞0.05).At 30 days after operation,the GQOL-74 score of the reswarch group was higher than that of the control group,and the GQOL-74 score of the two groups were higher than those before operation,the differences were statistically significant(P＜0.05).Conclusion During knee replacement,the ultrasound-guided continuous saphenous nerve block combined with multi-mode analgesia can efficiently shorten the hospitalization time,and improve the knee joint function and analgesia effects.It is worthy of application.
		2021 Vol. 28 (2): 116-119 [Abstract] ( 43 ) HTML (38 KB) PDF (0 KB) ( 7 )

	120	Effect of sedation depth of intravenous inhalational anesthesia on cognitive function of patients undergoing laparoscopic radical resection of cervical cancer
		GE Yu-ting
		Objective To investigate the effect of different sedation depths of intravenous inhalational anesthesia on the cognitive function of patients undergoing laparoscopic radical resection of cervical cancer.Methods A total of 80 patients undergoing laparoscopic radical cervical cancer surgery in Dalian Jinpu New District Maternal and Child Health Hospital from December 2017 to August 2019 were selected as research subjects.They were divided into the control group and the observation group by random drawing method,with 40 cases in each group.Deep anesthesia with the bispectral index(BIS)set as 40-50 was used in the observation group,while light anesthesia with the BIS set as 51-60 in the control group.The blood loss and blood pressure during surgery,postoperative wake-up time,time to speak after surgery and extubation time of the two groups were compared.The time to finish trail making test(TMT)and score of mini mental state scale(MMSE)before and after anesthesia were also compared.Results There were no statistically significant differences in intraoperative blood loss,blood pressure,wake-up time,time to speak,and extubation time between the two groups(P＞0.05).The MMSE score(27.32±0.81)points of the observation group at 1 d after anesthesia was higher than in control group(23.78±0.54)points,and the difference was statistically significant(P＜0.05).Time to finish TMT(40.02±1.34)s of the observation group at 1 d after anesthesia was shorter than in the control group(43.89±1.25)s,and the difference was statistically significant(P＜0.05).Conclusion In the treatment of patients undergoing laparoscopic radical resection of cervical cancer,deep intravenous inhalation anesthesia with BIS ranging from 40-50 can facilitate the postoperative cognitive recovery,and it is worthy of promotion and implementation in clinical practice.
		2021 Vol. 28 (2): 120-122 [Abstract] ( 41 ) HTML (32 KB) PDF (0 KB) ( 3 )

	123	Application of serratus anterior plane block under ultrasound in thoracoscopic pulmonary bullae surgery
		ZOU Jia-rui；KANG Hong-zhe；HUO Xiao-bei
		Objective To investigate application of serratus anterior plane block under ultrasound in thoracoscopic pulmonary bullae surgery.Methods A total of 80 patients undergoing thoracoscopic bullae surgery in Dalian Municipal Central Hospital from November 2019 to May 2020 were selected as the research subjects.According to the random number table method,they were divided into the control group and the observation group,with 40 cases in each group.In the control group,thoracic paravertebral nerve block was used,and in the observation group,ultrasound-guided serratus anterior block was adopted.The changes in pain numeric rating scale(NRS)scores during the recovery from anesthesia between the two groups were compared.The subjective comfort scores during the recovery from anesthesia between the two groups were compared.The condition of opioid adding once within 48 h after surgery was compared.The levels of pain mediators including substance P(SP)and nerve peptide Y(NPY)were compared between the two groups at 6 h after awakening from anesthesia.Results The pain NRS scores of the observation group at 2,6,12 h after awakening from anesthesia were lower than those of the control group,the differences were statistically significant(P＜0.05).The subjective comfort scores at 2,6,12 h after awakening from anesthesia in the observation group were higher than those of the control group,the differences were statistically significant(P＜0.05).The frequency of adding opioid analgesics once in the observation group at 48 h after operation was less than that in the control group,the difference was statistically significant(P＜0.05).6 h after awakening from anesthesia,the levels of SP and NPY were lower than those of the control group,the differences were statistically significant(P＜0.05).Conclusion For thoracoscopic surgery,the application of serratus anterior plane block under ultrasound can effectively alleviate patient′s postoperative pain,improve comfort,and reduce the dosage of opioid analgesics.
		2021 Vol. 28 (2): 123-125转129 [Abstract] ( 44 ) HTML (35 KB) PDF (0 KB) ( 7 )

	126	Clinical value of color Doppler echocardiography in the diagnosis of cor pulmonale
		ZHANG Bing
		Objective To study the clinical value of color Doppler echocardiography(CDE)in the diagnosis of cor pulmonale(CPM).Methods A total 70 patients with CPM who treated and accepted CDE examination in People′s Hospital of Lianshan District in Huludao City from December 2018 to December 2019 were selected as the study group,and 70 healthy physical examinees who underwent CDE during the same period were selected as the control group.The echocardiographic indexes and the pulmonary arterial hypertension of the two groups were compared.Results The myocardial systolic peak longitudinal strain(SL),left ventricular mass(LVM),left atrial volume(LAV),right ventricular anterior wall(RVAW),right ventricular(RV),right atrium(RA)and main pulmonary artery diameter(MPAD)of the study group were higher than those of the control group,the myocardial systolic peak radial strain(SR)and left ventricular ejection fraction(LVEF)were lower than those of the control group,and the differences were statistically significant(P＜0.05).The systolic blood pressure,diastolic blood pressure and mean pressure of pulmonary artery in the study group were(85.45±15.28),(42.64±9.59)and(70.84±9.44)mmHg.Among the 70 cases included in the study group,60 cases were diagnosed,accounting for 85.71% and 10 cases were not diagnosed,accounting for 14.29%.Conclusion CDE can accurately estimate the pulmonary arterial hypertension in patients with CPM,and has a high clinical value in the diagnosis of CPM.
		2021 Vol. 28 (2): 126-129 [Abstract] ( 45 ) HTML (37 KB) PDF (0 KB) ( 7 )

	130	Application value of coronary CTA in plaque property assessment of acute coronary syndrome
		SONG Yan
		Objective To explore the value of coronary CT angiography(CTA)in plaque property assessment of patients with acute coronary syndrome(ACS).Methods A total of 60 patients with ACS who were admitted to the Department of Radiology in People′s Hospital of Diaobingshan City from August 2016 to August 2019 were selected as the experimental group,and 60 patients with stable angina pectoris received at the same period were selected as the control group.The vascular volume,degree of lumen stenosis,reconstruction index(RI),total plaque volume,non-calcified plaque volume,calcified plaque volume,non-calcified plaque load,calcified plaque load,and CT value of minimum plaque density were compared between the two groups.Results The RI and non-calcified plaque loads in the experimental group were higher than those in the control group,and the differences were statistically significant(P＜0.05).There were no statistically significant differences in vascular volume,degree of lumen stenosis,total plaque volume,non-calcified plaque volume,calcified plaque volume,calcified plaque load between the two groups(P＞0.05).The CT value of minimum plaque density in the experimental group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion CTA can distinguish ACS from stable angina pectoris by evaluating the nature of plaque,and is suitable for clinical application.
		2021 Vol. 28 (2): 130-132 [Abstract] ( 36 ) HTML (33 KB) PDF (0 KB) ( 7 )

	133	Value of ultrasonic elastography in the diagnosis of benign and malignant superficial soft tissue masses
		ZHANG Xu
		Objective To investigate the value of ultrasound elastography in the diagnosis of benign and malignant superficial soft tissue masses.Methods A total of 75 patients who with diagnosed with superficial soft tissue benign and malignant masses in Anshan Tumor Hospital of Liaoning Province from January 2018 to December 2019 were selected as the study objects.Two-dimensional ultrasound examination and ultrasound elastography examination were used,and pathological surgery results were taken as the gold standard.The diagnostic accuracy,sensitivity and specificity of the two techniques were compared.Results The pathological surgery results showed that there were 60 benign masses and 27 malignant masses in 75 patients(87 masses).The diagnostic accuracy of two-dimensional ultrasound examination was 64.37%,the sensitivity was 44.44%,the specificity was 73.33%.The diagnostic accuracy of ultrasound elastography examination was 86.21%,the sensitivity was 74.07%,the specificity was 91.67%.The diagnostic accuracy,sensitivity and specificity of ultrasound elastography examination were higher than those of two-dimensional ultrasound examination,and the differences were statistically significant(P＜0.05).Conclusion Ultrasound elastography technology has a positive role in the diagnosis of benign and malignant superficial soft tissue masses,with high specificity and sensitivity,which can effectively distinguish benign and malignant masses and improve the diagnostic accuracy.
		2021 Vol. 28 (2): 133-135 [Abstract] ( 44 ) HTML (30 KB) PDF (0 KB) ( 7 )

	136	Experience of professor Chen Min-fan in treatment of anal fistula
		WANG Jing；WANG Zhao-chu；ZHONG Ling-yan； SHI Rong
		Anal fistula is common and difficult disease in anorectal department,especially high-grade fistula and complicated fistula,which is challenging for surgeons.Surgery is often confused about how to balance the anal sphincter function with the removal of the lesion.In his more than 60 years of teaching,research and clinical work in anorectal department,Professor Chen Min-fan has unique insights on the diagnosis and treatment and prevention of anal fistula,and summarized a complete ideological system.Professor Chen believes that anal fistula from the etiology of the mechanism more blamed on Damp-Heat,so anal fistula identification is mostly from Damp-Heat.The treatment of anal fistula should focus on both internal and external treatment,internal treatment to identify the evidence,external treatment to identify the disease.For the majority of patients with dampness and heat,Professor Chen added and subtracted on the basis of Er Miaosan,creating effective prescriptions such as Yellow White Mixture,Qing Toxin Drink and Qing Anus Drink.It has been found to have the effect of clearing heat and dampness,cooling blood and detoxification,reducing swelling and pain,and has developed anti-inflammatory ointment for external use.In terms of surgical treatment,Professor Chen Minfan put forward the idea of “saving the body with little loss” in the surgery of anal fistula,that is,focusing on the protection of anal morphology.The minimally invasive traditional chinese medicine concept of“preserving function and preserving shape” is realized by the combination of the characteristic hanging thread and skin-retention bridge.
		2021 Vol. 28 (2): 136-138转145 [Abstract] ( 52 ) HTML (34 KB) PDF (0 KB) ( 6 )

	139	Clinical effect of Wenjing Decoction combined with acupoint application on primary dysmenorrhea of cold coagulation and blood stasis type
		WU Hui-ping；GONG Xue；HONG Yan-yan
		Objective To explore the clinical effect of Wenjing Decoction combined with acupoint application in the treatment of patients with primary dysmenorrhea of cold coagulation and blood stasis type.Methods A total of 77 patients with primary dysmenorrhea of cold coagulation and blood stasis type treated in Jingdezhen Traditional Chinese Medicine Hospital from April 2018 to October 2019 were selected as research objects.The patients were divided into the reference group(38 cases)and the treatment group(39 cases)according to the even and odd grouping method.The reference group was given Ibuprofen Sustained-release Capsule treatment,and the treatment group was given Wenjing Decoction combined with acupoint sticking treatment.The dysmenorrhea symptoms,prostaglandin F2α level and overall efficacy of the two groups of patients before and after treatment were compared.Results Before treatment,there were no significant differences in dysmenorrhea time score,dysmenorrhea degree score and prostaglandin F2α level between the two groups(P＞0.05).After treatment,the scores of patients in the two groups were lower than those before treatment,the dysmenorrhea time score and dysmenorrhea score of the treatment group were lower than the reference group,the differences were statistically significant(P＜0.05).After treatment,the prostaglandin F2α level in patients of the two groups were lower than those before treatment,the prostaglandin F2α level of the treatment group was lower than the reference group,the differences were statistically significant(P＜0.05);The Total effective rate of treatment in the treatment group(92.31%)was higher than that in the reference group(71.05%),the difference was statistically significant(χ2=5.845,P=0.016).Conclusion The combination of Wenjing Decoction and acupoint application in the treatment of patients with primary dysmenorrhea with cold coagulation and blood stasis has obvious clinical advantages,which can effectively shorten the time of dysmenorrhea and relieve the degree of dysmenorrhea.At the same time,it can improve the prostaglandin F2α level and effectively improve the clinical efficacy,and the method can be popularize and applied.
		2021 Vol. 28 (2): 139-141 [Abstract] ( 57 ) HTML (33 KB) PDF (0 KB) ( 7 )

	142	Effect of Toubi Pill combined with acupuncture on cervical spondylotic radiculopathy
		HE Ji-fen；LAN Yi-kun；ZENG Rong-xiang；ZHANG Chun-sheng； QIN Biao-min
		Objective To explore the therapeutic effect of Toubi Pill combined with acupuncture in patients with cervical spondylotic radiculopathy.Methods A total of 62 patients with cervical spondylotic radiculopathy who were admitted to the Acupuncture and Moxibustion Department of Foshan Hospital of Traditional Chinese Medicine from January to September 2019 were selected as the research objects.According to the treatment methods,they were divided into the control group(31 cases)and the observation group(31 cases).The control group were treated with western medicine,the observation group were treated with Toubi Pill combined with acupuncture,7 d as one course of treatment,both groups were treated with 2 courses of treatment,followed up for 6 months.The clinical efficacy after treatment,recurrence rate and adverse reaction rate after 6 months follow-up were compared between the two groups.Results After treatment,the clinical efficacy of observation group was 90.32% higher than that of control group(64.52%),the difference was statistically significant(P＜0.05).After follow-up for 6 months,the recurrence rate and the incidence of adverse reactions in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Compared with the treatment of cervical traction combined with Indomethacin entericcoated tablets,the effect of Toubi Pill combined with acupuncture in the treatment of cervical spondylotic radiculopathy is better,with low recurrence rate,few adverse reactions,safe and effective,and worthy of clinical promotion.
		2021 Vol. 28 (2): 142-145 [Abstract] ( 56 ) HTML (38 KB) PDF (0 KB) ( 10 )

	146	Diagnostic value of combined detection of neutrophil to lymphocyte ratio,fibrinogen,CA199 and CEA in colon cancer
		CHEN Yu；ZHANG Yi-min； YE Liu-qing
		Objective To analyze the diagnostic value of combined detection of neutrophil to lymphocyte ratio(NLR),fibrinogen(FIB),CA199 and CEA in colon cancer.Methods A total of 174 patients with colon cancer who were first diagnosed in Zhejiang Cancer Hospital from January to June 2019 were selected as the colon cancer group,and 82 patients with benign colon lesions at the same period were selected as the control group.The levels of NLR,FIB,CA199 and CEA in the two groups were detected,and their clinical diagnostic value was analyzed.Results The levels of NLR,FIB,CAl99 and CEA in the colon cancer group were higher than those in the control group(P＜0.01).The sensitivity and accuracy of the four combined tests were higher than the results of CEA,CA199 single and combined tests(P＜0.05).Conclusion The combined detection of NLR,FIB,CAAl99 and CEA can effectively improve the diagnostic efficacy of tumor markers for colon cancer.
		2021 Vol. 28 (2): 146-148 [Abstract] ( 52 ) HTML (32 KB) PDF (0 KB) ( 7 )

	149	Value analysis of two pairs and a half quantitative detection of hepatitis B
		LIU Ya；CHEN Hong
		Objective To explore the value of two pairs and a half quantitative detection of hepatitis B.Methods A total of 15 184 cases of suspected hepatitis B patients admitted to Chuzhou Hospital of Integrated Traditional Chinese and Western Medicine from January 2018 to January 2020 were selected.The patients underwent two pairs and a half quantitative detection(chemiluminescence method)and qualitative detection(ELISA).The positive rates of two pairs and a half indexes,the detection rates of "big three positive" and "small three positive" of the two detection methods were observed,and the specificity,sensitivity and accuracy of the two detection methods were compared.Results The positive rates of HBeAg(13.59%)and HBeAb(57.90%)detected by quantitative detection of chemiluminescence method were higher than those of qualitative detection of ELISA(6.86%,31.30%),the differences were statistically significant(P＜0.05).There was no significant difference in the positive detection rate of HBsAg,HBsAb and HBcAb between quantitative detection by chemiluminescence method and ELISA qualitative detection(P＞0.05).The detection rate of "small three positive" in quantitative detection of chemiluminescence method(53.91%,8186/15 184)was higher than that of ELISA qualitative detection(39.68%,6025/15 184),the difference was statistically significant(P＜0.05).The specificity,sensitivity and accuracy of quantitative detection of chemiluminescence method were higher than those of qualitative detection of ELISA,the differences were statistically significant(P＜0.05).Conclusion The positive detection rate of two pairs and a half quantitative detection of hepatitis B is higher than that of qualitative detection,with higher specificity,sensitivity and accuracy,and higher clinical application value,which provides effective reference for clinical diagnosis and treatment.
		2021 Vol. 28 (2): 149-151 [Abstract] ( 48 ) HTML (30 KB) PDF (0 KB) ( 6 )

	152	Effect of strengthening the quality management of immunoassays on the detection rate of clinical immunoassays
		WANG Jing
		Objective To analyze the effect of strengthening the quality management of immunoassays on the detection rate of clinical immunoassays.Methods A total of 100 patients who underwent immune inspection in Anshan Central Hospital from June 2017 to June 2019 were selected as the research objects,and were divided into the test group and the control group according to random number table method,with 50 cases in each group.The control group adopts routine immune inspection quality management,while the test group adopts enhanced immune inspection quality management.The four detection rates of hepatitis B and the average variation index were compared and analyzed.Results The detection rates of hepatitis B surfaco antigen(HbsAg),hepatitis B surface antibody(HbsAb),hepatitis B eantigen(HbeAg)and hepatitis B virus coreantibady(HbcAb)in the four items of hepatitis B in the test group were higher than those in the control group,the differences were statistically significant(P＜0.05).Thyroid function,alpha-fetoprotein,and tumor markers in the test group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Strengthening the quality management of immunoassays can improve the accuracy of diagnosis of patients′ diseases.The clinical practice should be to actively promote the quality management of enhanced immunoassays in immunoassays.
		2021 Vol. 28 (2): 152-154 [Abstract] ( 44 ) HTML (32 KB) PDF (0 KB) ( 7 )

	155	Application value of thrombelastogram combined with detection of serum amyloid A in preeclampsia of pregnancy
		HUANG Xing-hong；LIN Yu-feng； XU Qiu-gui；CHEN Dong-ling
		Objective To investigate the application value of thrombelastogram(TEG)and serum amyloid A(SAA)detection in preeclampsia of pregnancy.Methods A total of 119 cases of preeclampsia patients who delivered in Yangjiang People′s Hospital from July 2018 to December 2019 were selected as the preeclampsia group.According to the diagnostic criteria of Obstetrics and Gynecology,they were divided into the mild preeclampsia group(58 cases)and the severe preeclampsia group(61 cases).A total of 60 pregnant women with normal late pregnancy during the same period were selected as the control group.Samples were collected for TEG and SAA detection,and statistical analysis was conducted.Results The response time(R)and coagulation time(K)of the mild preeclampsia group and the severe preeclampsia group were longer than those of the control group,SAA values of the mild preeclampsia group and the severe preeclampsia group were higher than those of the control group,while coagulation angle(Angle)and maximum thrombus amplitude(MA)of the mild preeclampsia group and the severe preeclampsia group were lower than those of the control group,the differences were statistically significant(P＜0.05).The R and K of the severe preeclampsia group were longer than those of the mild preeclampsia group,SAA value of the severe preeclampsia group was higher than that of the mild preeclampsia group,while Aangle and MA of the severe preeclampsia group were lower than those of the mild preeclampsia group,the differences were statistically significant(P＜0.05).Conclusion The indicators of TEG and SAA are closely related to the severity of preeclampsia in pregnancy,which can better understand the condition development of patients with preeclampsia and provide meaningful basis for the clinical treatment of this disease.
		2021 Vol. 28 (2): 155-157转165 [Abstract] ( 46 ) HTML (35 KB) PDF (0 KB) ( 7 )

	158	Investigation on the cognitive status of pressure injury by community nurses in Nanchang
		HU Qing-xia；HUANG Ru-yu；ZHU Qian
		Objective To investigate the nurses from community health service centers in Nanchang on their knowledge and skills of pressure injury.Methods From November 2019 to March 2020,a self-developed questionnaire was used to conduct a questionnaire survey of 189 nurses in 15 community health service centers in Nanchang,and the community nurses′ knowledge and skills on stress injuries were analyzed.Results The average score of knowledge and skills of community nurses on pressure injury was(69.60±13.87)points.There were no statistical differences in the scores of community nurses of different ages and educational backgrounds on the knowledge and skills of stress injuries(P＞0.05);the scores of nurses were lower than those of nurses and supervisors,and the differences were statistically significant(P＜0.05);the scores of nurses in community health service centers of level 1 and below were lower than those of community nurses merged by tertiary hospitals,and the differences were statistically significant(P＜0.05).The community nurses had the worst knowledge of stages of pressure injury,the correct rate was 48.15%,the correct rate of "wound treatment" was 53.97%,and the correct rate of"incontinence nursing"was 58.20%.22.75%of the nurses obtained the knowledge of pressure injury from a single book education,97.35% of the nurses were willing to take part in the study,and 94.71%of the nurses hoped to get remote guidance in time when nursing was difficult.Conclusion It is of great importance for the nurses from community health service centers in Nanchang to improve the knowledge and skills.
		2021 Vol. 28 (2): 158-161 [Abstract] ( 44 ) HTML (39 KB) PDF (0 KB) ( 9 )

	162	Results analysis of tuberculosis screening among freshmen in different types of schools in Fuxin city in 2019
		SHI Heng-yue；CHEN Xi
		Objective To understand the tuberculosis infection among freshmen in school above junior vocational school in Fuxin.Methods A total of 3997 freshmen from 9 junior high schools,vocational schools and special schools derectly under the Municipal Education Commission in Fuxin City in 2019 were surveyed by questionnaires and screened for tuberculosis.Results In 2019,3867 freshmen were screened for purified protein derivative(PPD)test in 9 schools in Fuxin City,with a strong positive rate of 6.31% and the incidence of tuberculosis among freshmen was 0.00%;there were significant differences in the strong positive rate among different types of schools(P＜0.05);the strong positive rate of students′ individual characteristics was statistically significant between urban and rural areas,between genders,and between boarding and non-boarding(P＜0.05);there was no statistically significant difference in the age distribution of the neonatal strong positive rate(P＞0.05).Conclusion On the screening of new students for tuberculosis is an effective means to control the tuberculosis epidemic in schools.The schools where the latent infected persons are found should focus on management,carry out health education regularly,establish a long-term mechanism for screening new students for tuberculosis,and reduce the prevalence of tuberculosis among students.
		2021 Vol. 28 (2): 162-165 [Abstract] ( 42 ) HTML (34 KB) PDF (0 KB) ( 5 )

	166	The investigation of COVID-19 patients′ psychological status and the analysis of influencing factors
		FAN Tian-qiong； XIONG Ying； LIU Dan-dan； ZHAO Jing-jing；WANG Qiu；ZHU Jin-ling
		Objective To investigate the psychological status of patients diagnosed with Coronavirus disease 2019(COVID-19)and analyze its influencing factors.Methods A total of 114 cases of confirmed COVID-19 patients admitted to the Chest Hospital of Jingzhou from January 2020 to March 2020 were selected as research objects.Self-made questionnaires were used to investigate the general information of patients,the SAS and SDS scores of each group were compared,and the influencing factors of psychological conditions such as anxiety and depression were analyzed by Logistic regression analysis.Results The SAS and SDS scores of COVID-19 patients were(49.74±10.52)points and(54.94±11.25)points,respectively.There were significant differences in gender,age,years of education,marital status,occupational status,monthly income,residence,basic diseases and sleep quality about the SAS and SDS scores of patients diagnosed with COVID-19(P＜0.05).Logistic regression analysis method showed that female,age 41-59 years old,years of education ＜9 years,married,unemployed,monthly income ＜3000 yuan,rural area,≥2 basic diseases and poor sleep quality were all risk factors for anxiety and depression in COVID-19 patients(P＜0.05).Conclusion The patients diagnosed with COVID-19 have severe anxiety and depression.The psychological nursing intervention measures should actively take in view of the various factors,so as to alleviate the negative emotions of patients such as anxiety and depression.
		2021 Vol. 28 (2): 166-169 [Abstract] ( 59 ) HTML (34 KB) PDF (0 KB) ( 7 )

	170	Disinfection and isolation measures of Novel Coronavirus pneumonia quarantine ward
		TANG Tian；WANG Guo-qin
		Novel Coronavirus pneumonia is a new respiratory infectious disease.There are high risk factors such as source of infection,transmission route and susceptible group between patients and medical staff in the ward.Therefore,the prevention and control of infection in the ward is an important job.Taking the case of the novel coronavirus pneumonia ward in Xiaogan Central Hospital as an example,this study discussed the disinfection measures and related procedures of the Novel Coronavirus pneumonia ward,in order to effectively reduce the risk of nosocomial infection and protect the health and safety of medical staff and patients.
		2021 Vol. 28 (2): 170-172 [Abstract] ( 53 ) HTML (33 KB) PDF (0 KB) ( 9 )

	173	Influence analysis of PDCA circulation management on nursing quality of blood purification room
		GUO Ding-hua；GUO Si-si
		Objective To explore the influence of PDCA circulation management on nursing quality of blood purification room.Methods A total of 270 hemodialysis patients who were admitted to the Third People′s Hospital of Huizhou from January 2017 to June 2019 were selected as the observation objects.They were divided into the observation group(n=135)and the control group(n=135)according to random number table method.The observation group was given PDCA circulation management nursing,while the control group was given routine nursing.The nursing compliance,the incidence of adverse events(nurse patient disputes)and nursing satisfaction were compared between the two groups.Results The total satisfaction of the observation group was 99.25%,which was higher than 88.89% of the control group,the difference was statistically significant(P＜0.05).The total nursing compliance rate of the observation group was 98.52%,which was higher than 88.89% of the control group,the difference was statistically significant(P＜0.05).The incidence of nurse patient disputes in the observation group was 0.00%,which was lower than 5.18% of the control group,the difference was statistically significant(P＜0.05).Conclusion The application of PDCA circulation management in the nursing of hemodialysis patients can effectively improve the nursing compliance of severe patients,reduce the incidence of adverse events,enhance the nursing satisfaction of patients,and the clinical effect is significant,which is worthy of promotion.
		2021 Vol. 28 (2): 173-175 [Abstract] ( 39 ) HTML (31 KB) PDF (0 KB) ( 7 )

	176	Practice and thinking on the deep integration of the work of party building and professional work in public hospital
		GU Jun
		Party building is an important part of the work in public hospitals,and its status and role are self-evident.Currently,each public hospital is also actively carrying out the work of party building,but the actual role of the party building has not been fully highlighted in professional work.In the integration of party building and professional work,some urgent problems still inevitably emerge.This study first analyzed the current problems in the party building in public hospitals,further clarified the necessity of the integration of party building and professional work in public hospitals,and finally put forward some practical strategies for deepening the integration of party building and professional work in public hospitals.The purpose is to offer some reference and help for the party workers in hospitals.
		2021 Vol. 28 (2): 176-178 [Abstract] ( 39 ) HTML (32 KB) PDF (0 KB) ( 7 )

	179	Application effect of infectious disease management system and prevention and control linkage mechanism in comprehensive hospital infectious disease management
		WANG Xi-xi
		Objective To explore the effect of infectious disease management system and prevention and control linkage mechanism in the management of infectious diseases in general hospitals to actively prevent and control infectious diseases.Methods The 873 cases of suspected infectious diseases reported before the implementation of infectious disease management system and control linkage mechanism for prevention and control by Donggang Central Hospital in October 2018(September 2017 to September 2018)and 1067 cases of suspected infectious diseases reported after the implementation(October 2018 to October 2019)were studied,and the diagnosis and patient satisfaction before and after implementation were compared.Results Infectious disease management system and prevention and control linkage mechanism were reported to 873 cases of suspected infectious diseases before implementation,107 cases were diagnosed as infectious diseases,accounting for 12.26%(107/873),after implementation,suspected infectious diseases were directly reported to 1067 cases,334 diagnosed cases were diagnosed as infectious diseases,accounting for 30.31%(334/1067),after implementation was higher than before implementation,and the difference was statistically significant(χ2=9.152,P=0.021).The satisfaction of infectious disease management effect was 97.31% after implementation,which was higher than 78.83% before implementation,and the difference was statistically significant(χ2=12.054,P=0.001).Conclusion The application of the infectious disease management system and the prevention and control linkage mechanism in the management of infectious diseases in comprehensive hospitals can effectively detect and control infectious diseases and has the value of popularization and application.
		2021 Vol. 28 (2): 179-181转189 [Abstract] ( 45 ) HTML (34 KB) PDF (0 KB) ( 8 )

	182	Disease spectrum analysis of inpatients of the new rural cooperative medical system in Shenyang
		FU Wen-hua；GU Jing； CONG Chuang； ZHOU Qiang； LIN Xue-nan； LIU Shuang； LIU Hai-tao
		Objective To explore the characteristics of disease spectrum of inpatients of new rural cooperative medical system(NRCMS)in Shenyang,and to provide scientific basis for formulating disease prevention and control strategies of rural population.Methods Based on the basic information of the participants of the NRCMS in Shenyang from January 1,2018 to December 31,2019,and the hospitalization related data during this period,the hospitalization rate of rural residents was calculated,and the hospitalization disease spectrum of different age and gender groups was analyzed.Results The hospitalization rate of rural residents was 14.3‰,and the standardized hospitalization rate was 11.6‰.The hospitalization rate of women was higher than that of men.The hospitalization rate of the elderly over 59 years old and children 0-4 years old were higher than that of other age groups(P＜0.01).The top 4 system diseases affecting the health of rural residents were circulatory system diseases,tumors,respiratory system diseases and digestive system diseases,accounting for 66.8% of the total inpatients.The disease spectrum was different for different age groups,gender and districts.Conclusion The utilization rate of inpatient health services of rural residents in Shenyang is lower.The diseases of circulatory system,tumor,respiratory system and digestive system are the main diseases threatening the health of local rural residents.According to the disease hospitalization spectrum of different groups,targeted prevention and control measures should be carried out,the prevention and control of tumors,cardiovascular and cerebrovascular diseases and respiratory diseases should be focused,medical and health resources should be reasonably adjusted to promote the health of rural population.
		2021 Vol. 28 (2): 182-185 [Abstract] ( 46 ) HTML (35 KB) PDF (0 KB) ( 6 )

	186	Influence of continuous follow-up combined with health education on the tolerance and compliance of antiviral therapy in acquired immune deficiency syndrome patients
		RAO Hong-mei
		Objective To investigate the influence of continuous follow-up combined with health education on the tolerance and compliance of anti viral treatment in acquired immune deficiency syndrome(AIDS)patients.Methods A total of 80 AIDS patients from October 2018 to April 2019 in Fuzhou First People′s Hospital were selected and divided into the control group(n=40)and the observation group(n=40)according to different research methods.The control group adopted health education mode,and the observation group adopted continuous follow-up combined with health education.The negative emotions,self-efficacy,tolerance and Morisky compliance of the two groups were observed.Results The self-efficacy score of the observation group after nursing was higher than that of the control group,the scores of self-rating anxiety scale(SAS)and the self-rating depression scale(SDS)of the observation group after nursing were lower than those of the control group,the differences were statistically significant(P＜0.05).The incidence rates of tension,fear and conflict in the observation group were lower than those in the control group,with significant differences(P＜0.05).The incidence rates of active informing and facing frankly in the observation group were higher than those in the control group,with significant differences(P＜0.05).The compliance of patients in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).Conclusion Continuous follow-up combined with health education can significantly improve the tolerance and compliance of antiviral treatment in AIDS patients,alleviate the negative emotions of patients,improve self-efficacy,and have high application value.
		2021 Vol. 28 (2): 186-189 [Abstract] ( 45 ) HTML (34 KB) PDF (0 KB) ( 6 )

	190	Application of ward rounds of single disease based on CBL in standardized training of neurophysicians
		LIU Shu-dong； LI Wen-yan
		Ward rounds of single disease teaching based on CBL is a group discussion teaching method.Its core is case as the guide,problem as the basis,student as the main body and teacher as the leading role.The combination of real cases not only can help physicians who are undergoing standardized resident training(hereinafter referred to as"regular training")quickly familiar with the clinical working procedures,but also continuously revises the clinical thinking in the course of diagnosis and treatment through the communication and discussion between the teachers and regular training physicians,as well as among regular training physicians in the group.It can promote the improvement of clinical thinking ability of regular training physicians of different levels,thus greatly improving the level of clinical diagnosis and treatment of neurological diseases of regular training physicians.
		2021 Vol. 28 (2): 190-192转196 [Abstract] ( 45 ) HTML (35 KB) PDF (0 KB) ( 8 )

	193	Application of curriculum teaching reform based on the outcome-based education concept in clinical blood transfusion practice
		TANG Dai-yu；JIANG Xiao-chun
		Objective To investigate the application effect of curriculum teaching reform based on the outcome-based education concept in clinical blood transfusion practice.Methods A total of 144 students of medical laboratory science who practiced in Department of Blood Transfusion in the Third People′s Hospital of Yunnan Province from July 2015 to August 2017 and September 2017 to January 2020 were selected as the control group(49 cases)and the observation group(95 cases)by convenience sampling method.The control group adopted the traditional clinical teaching mode,and the observation group adopted the outcome-based education mode.The theoretical knowledge assessment result,operational skills assessment result and teaching mode satisfaction were compared between the two groups.Results The theoretical knowledge assessment score of the observation group was lower than that of the control group,the operational skills assessment score was higher than that of the control group,and the differences were statistically significant(P＜0.05).The satisfaction of teaching mode in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The concept of outcome-based education in clinical blood transfusion practice can fully mobilize students′ learning enthusiasm and initiative,effectively improve the clinical practice effect of blood transfusion interns,improve the teaching quality,and have a good teaching effect.
		2021 Vol. 28 (2): 193-196 [Abstract] ( 36 ) HTML (36 KB) PDF (0 KB) ( 8 )

	197	Discussion and practice on training methods of three-level isolation and protection technology during anti-epidemic period
		LI Mao；PENG Na； HE Juan
		Objective To discuss the training methods and practical effect of the three-level isolation protection technology during the anti-epidemic period.Methods From January 26 to March 17,2020,the second batch of 72 aiding-Hubei medical staff from Daping Hospital of Army Military Medical University were selected to receive training on Novel Coronavirus pneumonia related knowledge and third-level isolation protection of wear and take off.The isolation and protection technology operation results after training were compared with those of the first batch of 34 aiding-Hubei medical staff selected from Daping Hospital of Army Military Medical University on January 24,2020.At the same time,the occurrence of common problems in the operation of protection and isolation technology were compared between the two batches of aiding-Hubei medical staff.Results The operational performance,pass rate and excellence rate of the second batch of aiding-Hubei medical staff were higher than those of the first batch of aiding-Hubei medical staff,and the differences were statistically significant(P＜0.001).The incidence rates of operational problems in the preparation stage,process,hand hygiene,dressing stage and unloading stage of the second batch of aiding-Hubei medical staff were lower than those of the first batch of aiding-Hubei medical staff,with statistically significant differences(P＜0.001).There was no statistically significant difference in the incidence of operational problems in disposal between the two batches of aiding-Hubei medical staff(P＞0.05).Conclusion The training method of three-level isolation and protection technology can greatly improve the theory and operation technology of three-level isolation and protection technology of medical staff,and can provide a powerful reserve force for aiding Hubei Province.
		2021 Vol. 28 (2): 197-200 [Abstract] ( 46 ) HTML (41 KB) PDF (0 KB) ( 7 )

	201	False negative analysis of 1 case of pulmonary nodule diagnosed by SHOX2 and RASSF1A genes combination methylation detection
		ZHOU Miao； YAN Wu-ling； ZHAO Dong-liang； LIU Yuan-yuan； JIAO Li
		The Department of Pulmonary Disease of the Third Affiliated Hospital of Henan University of Traditional Chinese Medicine has developed methylation detection technology for the combination of short stature homeobox 2(SHOX2)and Ras association domain family 1 A(RASSF1A)genes for the diagnosis of pulmonary nodules and early screening of lung cancer.Among them,the results of 1 case were not consistent with the surgical pathology results and presented false negative results.This paper analyzed the reasons for the false negative results in this case,which may be related to the improper selection of specimen types,insufficient specimen volume,and different positive rates and sensitities of SHOX2 and RASSF1A genes combination methylation detection for lung cancer with different pathological types and different degrees of differentiation.
		2021 Vol. 28 (2): 201-204 [Abstract] ( 53 ) HTML (34 KB) PDF (0 KB) ( 6 )

	205	Nursing experience of pulmonary embolism after successful treatment of 1 case of esophageal cancer
		JIANG Yue
		This paper summarized the nursing experience of a patient with pulmonary embolism after successful treatment of esophageal cancer,including early identification and nursing points.Based on the monitoring of the patient′s vital signs and observation of the patient′s condition,timely implementation of targeted and effective intervention measures,such as medication management,pain management and psychological intervention,effective airway management,nasal high-flow oxygen therapy nursing,nursing after implantation of lower vena cava filter,nutritional care and preventive measures.After timely treatment,precise treatment and careful nursing,the patient recovered well.After 16 days in intensive care ward,the patient was successfully transferred to the general ward for further treatment.After 6 days,the patient was discharged smoothly.
		2021 Vol. 28 (2): 205-209 [Abstract] ( 44 ) HTML (42 KB) PDF (0 KB) ( 6 )

	210	Analysis of 1 case of chondroid lipoma of left lower limb
		LIU Yu-bo ；ZHANG Duo
		Chondroid lipoma was an extremely rare benign tumor.At present,there were few reports about chondroid lipoma,which is easy to be misdiagnosed in clinical work.In this case,an elderly male patient was introduced.He was admitted to the hospital because of a 7 cm×4 cm mass in the posterior medial side of the left thigh.This mass increased slowly after no treatment.The skin color and temperature of the affected area were normal without tenderness.The sensation,movement and blood circulation of the left lower limb were normal.Ultrasound showed that there were 6.6 cm×3.1 cm×2.6 cm slightly hyperechoic mass in the left thigh posterior medial muscle,with clear boundary and complete capsule,many fibrous cord like hyperechoic distribution and sparse blood flow signal in the mass.On plain MRI scan,there was an elliptical abnormal signal shadow in the left thigh semimembranous muscle,the range was about 2.7 cm×3.7 cm×6.4 cm,the boundary was clear,the internal signal was slightly uneven,T1WI and T2WI were high signal,T2 fat suppression sequence was slightly lower than T2WI signal,showing slightly high signal,and the adjacent muscle was slightly compressed.The cortex of the left femur is smooth and continuous,and the signal is uniform.There is no obvious abnormal signal in the bone marrow.On contrast-enhanced MRI scan,there were obvious streaked enhancement shadow in the oval lesions of left thigh semimembranous muscle,but most of the lesions were not enhanced.The final diagnosis was chondroid lipoma after operation combined with pathology.In this paper,through the introduction of this case and the review of previous literature,to deepen the understanding of chondroid lipoma,aiming to reduce the incidence of misdiagnosis and avoid over treatment.
		2021 Vol. 28 (2): 210-213 [Abstract] ( 41 ) HTML (34 KB) PDF (0 KB) ( 7 )

	214	Application effect of high-quality nursing plan on patients with auricle pseudocyst by anterior wall cartilage resection combined with regional drainage
		CHEN Zhi-fang；LU Hua； HE Li-xing； ZHONG Xiao-hong； ZHENG Jie-yi
		Objective To explore the application effect of high-quality nursing program in the treatment of auricle pseudocyst with anterior wall cartilage resection combined with regional drainage.Methods From November 2018 to November 2019，100 patients with auricle pseudocysts admitted in Dongguan Huangjiang Hospital were selected as the sample，and were divided into observation group and control group according to random number table method，50 cases in each group.Patients in both groups were treated with anterior wall cartilage resection combined with regional drainage treatment.The observation group used high-quality nursing programs and the control group used conventional nursing programs.The total clinical treatment efficiency，total postoperative recovery,total incidence of complications and quality of care of the two groups of patients were compared.Results The total effective rate of postoperative recovery in the observation group was higher than that of the control group，the total incidence of complications was lower than that of the control group，the total nursing satisfaction was higher than that of the control group，and the nursing quality score was higher than that of the control group，the differences were statistically significant（P＜0.05）.Conclusion For patients undergoing anterior wall cartilage resection combined with regional drainage to treat auricle pseudocysts，it is necessary to supplement the nursing with high-quality nursing programs during the perioperative period to improve the postoperative recovery effect，reduce the incidence of complications，and improve the quality of nursing.
		2021 Vol. 28 (2): 214-216 [Abstract] ( 43 ) HTML (33 KB) PDF (0 KB) ( 9 )

	217	Effect of comprehensive nursing model on prognosis of respiratory failure in children under intensive care
		YANG Hong
		Objective To analyze the effect of comprehensive nursing model on the prognosis of respiratory failure in intensive care children.Methods From May 2018 to April 2020,80 patients with respiratory failure in Fuzhou First People′s Hospital,Jiangxi Province were selected as the research objects.According to the touch ball method，they were divided into study group(n=40)and the control group(n=40).The study group adopted the comprehensive nursing model,the control group adopted routine nursing mode.The total nursing satisfaction,the time of heat regression,the time of lung rale disappearance,the time of cough disappearance and the total incidence of complications were compared between the two groups.Results The total nursing satisfaction of the study group was higher than that of the control group,the difference was statistically significant（P＜0.05）.The fever regression time，lung rale disappearance time and cough disappearance time in the study group were shorter than those in the control group,the differences were statistically significant(P＜0.05).The total incidence of respiratory diseases,pulmonary encephalopathy and multiple infections in the study group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion The implementation of comprehensive nursing model can effectively improve the nursing effect of children with respiratory failure,reduce the total incidence of complications,have high safety,make children recover health as soon as possible,and have clinical application value.
		2021 Vol. 28 (2): 217-219 [Abstract] ( 42 ) HTML (33 KB) PDF (0 KB) ( 10 )

	220	Application effect of fast-track surgery nursing in elderly patients with high-risk benign prostatic hyperplasia and bladder stones
		LIU Yu-jian； HUANG Jian； LIN Si-min；CHEN Shen-quan； CHEN Cai-mei
		Objective To explore the effect of fast-track surgery(FTS)nursing on perioperative period in elderly patients with high-risk prostate hyperplasia(BPH)and bladder stones.Methods A total of eighty elderly patients with high-risk BPH and bladder stones admitted to Zhaoqing Second People′s Hospital,Guangdong Province from October 2018 to October 2019 were selected as the research subjects.They were divided into the control group and the observation group according to the random number table method,40 cases in each group.The control group was given routine nursing and the observation group was given FTS nursing on the basis of the control group.The postoperative recovery,pain,anxiety and postoperative complications of the two groups were compared.Results After the operation,the duration of bladder flushing,urinary indwelling time,first time to get out of bed,first exhaust time and hospitalization time in the observation group were shorter than those in the control group,the differences were statistically significant(P＜0.05).The total incidence of complications in the observation group was 12.50%,lower than that in the control group of 32.50%,the difference was statistically significant(P＜0.05).Three days after the operation,the visual pain analogue scale(VAS)score and self-rating anxiety scale(SAS)score of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).Conclusion FTS nursing can effectively shorten the postoperative recovery time of patients with BPH combined with bladder lithotripsy,relieve patients′ pain,improve their anxiety state,and reduce the incidence of complications.
		2021 Vol. 28 (2): 220-222转229 [Abstract] ( 44 ) HTML (36 KB) PDF (0 KB) ( 5 )

	223	Influence of continuous nursing on psychological state，quality of life and nursing satisfaction of patients with hepatitis B cirrhosis after discharge
		CHEN You-lian；FU Guang-lei； XU Yun-yao； LIN Gui-mei；CHEN Li-xia
		Objective To explore the influence of continuous nursing on psychological state,quality of life and nursing satisfaction of patients with hepatitis B cirrhosis after discharge.Methods A total of 120 cases of hepatitis B cirrhosis admitted to the Third Affiliated hospital of Sun yat-sen University,Yuedong Hospital from April 2018 to July 2019 were selected as research objects and divided into control group(n=60)and intervention group(n=60)according to the coin tossing method.The control group received single routine nursing,while the intervention group received routine nursing and continuing nursing.The quality of life and psychological state of the two groups were compared.Results After nursing,Hamilton depression rating scale(HAMD)and Hamilton anxiety scale(HAMA)scores of the intervention group were lower than those of the control group,and the differences were statistically significant(P＜0.05),HAMD and HAMA scores of the two groups before nursing,the differences were not statistically significant(P＞0.05).After nursing,the scores of physical state function,social function,psychological function and physical function of the intervention group were higher than those of the control group,with statistical differences(P＜0.05).The nursing total satisfaction of the intervention group was 96.67% higher than that of the control group of 83.33%,with statistical difference(P＜0.05).Conclusion Continuous nursing can not only improve the negative emotions of patients with hepatitis B cirrhosis,such as depression and anxiety,but also improve the quality of life and nursing satisfaction.It is worthy of adoption and promotion in clinical practice.
		2021 Vol. 28 (2): 223-225转233 [Abstract] ( 41 ) HTML (34 KB) PDF (0 KB) ( 7 )

	226	Application effect of Maslow′s hierarchy of needs in postoperative nursing of breast cancer patients
		DENG Jing；LAI Yong-ying；LUO Yan-ying；DING Yan-yu
		Objective To explore the application effect of Maslow′s hierarchy of needs in postoperative nursing of breast cancer patients.Methods A total of 40 breast cancer patients who were treated in Huizhou Maternal and Child Health and Family Planning Service Center,Guangdong Province from January 2017 to December 2018 were selected as the research subjects.They were divided into the control group and the study group according to the random number table method,20 cases in each group.In the control group,conventional nursing was used,and in the study group,Maslow′s hierarchy of needs nursing was adopted.The range of motion(ROM),the self-rating depression scale(SDS)score,the self-rating anxiety scale(SAS)score and the quality of life score of the two groups were compared.Results The ROM qualified rate of the study group was higher than that of the control group,and the difference was statistically significant(P＜0.05).There were no statistically significant differences in SDS,SAS,or quality of life score between the two groups before intervention(P＞0.05).The SDS and SAS scores of the two groups after interventions were lower than those before interventions,and the differences were statistically significant(P＜0.05).The quality of life scores of the two groups were higher than those before intervention,and the differences were statistically significant(P＜0.05).The SDS and SAS scores of the study group were lower than those of the control group,and the differences were statistically significant(P＜0.05).The quality of life in the study group was higher than that of the control group,with statistical difference(P＜0.05).Conclusion The application of Maslow′s hierarchy of needs in postoperative nursing of breast cancer patients can improve their mental state,promote the recovery of the limb function,and improve the quality of life.
		2021 Vol. 28 (2): 226-229 [Abstract] ( 45 ) HTML (33 KB) PDF (0 KB) ( 5 )

	230	Application effect of pre-appointment and education process intervention in day operation under general anesthesia for children in stomatology department
		HE Jia
		Objective To explore the application effect of pre-appointment and education process intervention in day operation under general anesthesia for children in stomatology department.Methods The clinical data of 124 children who had undergone day operation under general anesthesia in Dalian Stomatological Hospital,Liaoning Province from January to September 2019 were retrospectively analyzed.Subjects were divided into the control group(n=58,routine nursing)and the observation group(n=58,pre-appointment and education process intervention)according to the nursing method.The operation situation,treatment compliance,adverse reactions and family members′ satisfaction were compared between the two groups.Results The first ambulation time and length of hospital stay of the observation group were shorter than those of the control group,with statistical differences(P＜0.05),and treatment compliance was higher than that of the control group,with statistical difference(P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,with statistical difference(P＜0.05).Total satisfaction of family members with processes such as registration and treatment,waiting time for taking medicine and payment,doctor′s diagnosis and treatment and medical staff′s service attitude in the observation group were higher than those in the control group,with statistical differences(P＜0.05).Conclusion The application effect of pre-appointment and education process intervention in children undergoing day operation under general anesthesia in stomatology department can not only shorten the length of hospital stay,improve treatment compliance and reduce postoperative adverse reactions but also improve the family members′ satisfaction.
		2021 Vol. 28 (2): 230-233 [Abstract] ( 37 ) HTML (35 KB) PDF (0 KB) ( 8 )

	234	Application effect of clinical nursing path intervention in children′s infusion nursing
		SUN Qiu-hong；MO Li-fang
		Objective To analyze the application effect of clinical nursing pathway intervention in children infusion nursing.Methods From June 2018 to June 2019,200 pediatric infusion patients admitted to Beijing Aerospace General Hospital were selected as the study objects.According to the random number table method,they were divided into reference group and observation group,100 cases in each group.The observation group was intervened by clinical nursing route,and the reference group was treated by routine nursing.The compliance,pain.residual amount of liquid medicine and the recognition and satisfaction of the family members of the two groups were compared.Results The visual analogue scale(VAS)score of children in the observation group was lower than that in the reference group,the residual amount of drug solution was less than that in the control group,the infusion compliance score and the awareness of family members were higher than those in the control group,the differences were statistically significant(P＜0.05).The total nursing satisfaction of the family members in reference group(96.00%)was higher than that in the control group,the difference was statistically significant(P＜0.05).The success rate of 97.00%（97/100）was higher than that of 90.00%（90/100）in the reference group,the difference was statistically significant(P＜0.05).Conclusion The clinical nursing path intervention can effectively improve the nursing effect of children infusion,and improve the nursing satisfaction of children′s families.
		2021 Vol. 28 (2): 234-236 [Abstract] ( 46 ) HTML (31 KB) PDF (0 KB) ( 9 )

	237	Effect of comprehensive nursing intervention on the pain degree，mental state and quality of life in patients with appendicitis
		ZUO Pin；SUN Jian； ZHANG Jun
		Objective To evaluate the effect of comprehensive nursing intervention on the degree of pain,mental state,and quality of life for patients undergoing appendectomy.Methods A total of 122 patients undergoing appendectomy in Dalian Third People′s Hospital from August 2017 to January 2019 were selected.They were divided into control group(n=61)and study group(n=61)following the principle of randomized control.The control group used routine nursing,the study group used routine nursing plus comprehensive nursing.The surgical-related indicators,pain degree,mental state and quality of life were compared in the two groups.Results The postoperative defecation time,anal exhaust time,bed time and hospital stay in the study group were shorter than those in the control group(P＜0.05).The visual analogue scale(VAS)score at 24 h after surgery was lower than that in the control group,the total incidence of postoperative complications of the study group was lower than that in the control group,with statistical differences(P＜0.05).In the study group,the scores of the Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD)three months after surgery were lower than those of the control group,the score of comprehensive quality of life assessment questionnaire(GQOLI-74)was higher than that of the control group,and the differences were statistically significant(P＜0.05).Conclusion Comprehensive nursing intervention for patients undergoing appendectomy can speed up their postoperative recovery,alleviate pain,relieve poor mental state,improve postoperative quality of life,and reduce the risk of complications.
		2021 Vol. 28 (2): 237-240 [Abstract] ( 49 ) HTML (38 KB) PDF (0 KB) ( 7 )

Copyright © Editorial Board of 中国当代医药
Supported by:Beijing Magtech