血小板输注次数及输血小板前预防性用药对输血反应发生率的影响

Abstract
Figure/Table
References (17)
Related Citation (0)

Download: PDF (0 KB) HTML (27 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study the influence of platelet transfusion times and preventive medication before platelet transfusion on the incidence of blood transfusion reactions.Methods The incidence of blood transfusion reactions after platelet transfusion in 170 patients in the Department of Hematology,Shangrao People′s Hospital from February 2017 to August 2018 was investigated,they were divided into M1 group(＜5 times),M2 group(5-9 times)and M3 group(≥10 times)according to the number of platelet transfusions of the same patient,according to the history of transfusion reactions,they were divided into group with history of transfusion reactions and group without history of transfusion reactions,the influence of different blood transfusion times and preventive medication on the incidence of blood transfusion reactions was analyzed.Results A total of 784 cases of platelet transfusions were performed in 170 patients with hematologic diseases requiring platelet transfusion,there were 61 transfusion reactions,the incidence of transfusion reactions was 7.8%.There was statistically significant difference in the incidence of transfusion reactions among patients in the M1,M2,and M3 groups(P＜0.05).There was no statistically significant difference in the incidence of blood transfusion reactions in the three groups of M1,M2 and M3 with and without preventive medication(P＞0.05).There was statistically significant difference in the incidence of transfusion reactions between the group without history of transfusion reactions and the group with history of transfusion reactions(P＜0.05).There was no statistically significant difference in the incidence of blood transfusion reaction in the case of preventive medication and no preventive medication in the group with or without history of transfusion reactions(P＞0.05).Conclusion The more times of blood transfusion,the more patients with adverse reactions of blood transfusion.The incidence of blood transfusion reactions in patients with history of blood transfusion reaction is higher than that in patients without history of blood transfusion reaction.Preventive medication has no effect on the incidence of blood transfusion reactions in patients with multiple blood transfusions and those with a history of blood transfusion reactions.

Key words： Mechanical platelet collection Adverse reactions of blood transfusion Preventive medication

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I2/22

[3]	Savinkina AA，Haass KA，Sapiano MRP，et al.Transfusionassociated adverse events and implementation of blood safety measures-findings from the 2017 National Blood Collection and Utilization Survey[J].Transfusion，2020，60 Suppl 2：S10-S16.
[13]	王叶，胡小春，梁翠容，等.输血前预防用药对输血反应发生率影响的Meta 分析[J].循证护理，2017，3（5）：446-450.
[17]	Wang SE，Lara PN Jr，Lee-Ow A，et al.Acetaminophen and diphenhydramine as premedication for platelet transfusions：a prospective randomized double-blind placebo-controlled trial[J].Am J Hematol，2002，70（3）：191-194.
[4]	Mardani A，Balali MR.Transfusion reactions：A retrospective analysis of the Iranian national haemovigilance system（INHS）data[J].Transfus Apher Sci，2020，59（4）：102 767.
[5]	Daurat A，Roger C，Gris J，et al.Apheresis platelets are more frequently associated with adverse reactions than pooled platelets both in recipients and in donors：a study from French hemovigilance data[J].Transfusion，2016，56（6）：1295-1303.
[8]	Yamanaka M，Yanagisawa R，Kojima S，et al.Investigation of factors associated with allergic transfusion reaction due to platelet transfusion and the efficacy of platelets resuspended in BRS-A in adult patients[J].Transfusion，2019，59（11）：3405-3412.
[11]	Geiger TL，Howard SC.Acetaminophen and diphenhydramine premedication for allergic and febrile nonhemolytic transfusion reactions：good prophylaxis or bad practice?[J].Transfus Med Rev，2007，21（1）：1-12.
[12]	Fujiwara SI，Kino S，Tanaka A，et al.A national survey of premedication for transfusion reactions in Japan[J].Transfus Apher Sci，2017，56（5）：708-712.
[14]	Duran J，Siddique S，Cleary M.Effects of leukoreduction and premedication with acetaminophen and diphenhydramine in minimizing febrile nonhemolytic transfusion reactions and allergic transfusion reactions during and after blood product administration：a literature review with recommendations for practice[J].J Pediatr Oncol Nurs，2014，31（4）：223-229.
[15]	Ning S，Solh Z，Arnold DM，et al.Premedication for the prevention of nonhemolytic transfusion reactions：a systematic review and meta-analysis[J].Transfusion，2019，59（12）：3609-3616.
[16]	Aubron C，Aries P，Le Niger C，et al.How clinicians can minimize transfusion-related adverse events?[J].Transfus Clin Biol，2018，25（4）：257-261.
[2]	Yazer MH，Shaz B，Seheult JN，et al.Trends in platelet distributions from 2008 to 2017：a survey of twelve national and regional blood collectors[J].Vox Sang，115（8）：703-711.
[6]	张晰，冯明亮，沈彤，等.单采血小板输血反应调查及其输注无效解决策略[J].中国输血杂志，2008，21（6）：455-457.
[7]	陈利达，芦宏凯，王璐璐，等.北京市某三甲医院输血不良反应回顾分析[J].中国输血杂志，2016，29（2）：186-188.
[9]	罗圆圆，陈麟凤，汪德清.132 例血液病患者血小板输注效果的影响因素分析[J].标记免疫分析与临床，2015，22（9）：835-838，845
[10]	郝欣欣，高娃，何燕京，等.滤白机采血小板输注不良反应回顾性调查[J].中国输血杂志，2019，32（2）：189-192
[1]	Ellingson KD，Sapiano MRP，Haass KA，et al.Continued decline in blood collection and transfusion in the United States-2015[J].Transfusion，2017，57 Suppl 2（Suppl 2）：1588-1598.