乙型肝炎两对半定量检测的价值分析

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Abstract Objective To explore the value of two pairs and a half quantitative detection of hepatitis B.Methods A total of 15 184 cases of suspected hepatitis B patients admitted to Chuzhou Hospital of Integrated Traditional Chinese and Western Medicine from January 2018 to January 2020 were selected.The patients underwent two pairs and a half quantitative detection(chemiluminescence method)and qualitative detection(ELISA).The positive rates of two pairs and a half indexes,the detection rates of "big three positive" and "small three positive" of the two detection methods were observed,and the specificity,sensitivity and accuracy of the two detection methods were compared.Results The positive rates of HBeAg(13.59%)and HBeAb(57.90%)detected by quantitative detection of chemiluminescence method were higher than those of qualitative detection of ELISA(6.86%,31.30%),the differences were statistically significant(P＜0.05).There was no significant difference in the positive detection rate of HBsAg,HBsAb and HBcAb between quantitative detection by chemiluminescence method and ELISA qualitative detection(P＞0.05).The detection rate of "small three positive" in quantitative detection of chemiluminescence method(53.91%,8186/15 184)was higher than that of ELISA qualitative detection(39.68%,6025/15 184),the difference was statistically significant(P＜0.05).The specificity,sensitivity and accuracy of quantitative detection of chemiluminescence method were higher than those of qualitative detection of ELISA,the differences were statistically significant(P＜0.05).Conclusion The positive detection rate of two pairs and a half quantitative detection of hepatitis B is higher than that of qualitative detection,with higher specificity,sensitivity and accuracy,and higher clinical application value,which provides effective reference for clinical diagnosis and treatment.

Key words： Hepatitis B Two pairs and a half Quantitative detection Chemiluminescence Qualitative detection Diagnostic value

Received: 25 May 2020

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	LIU Ya
	CHEN Hong

Cite this article:

LIU Ya,CHEN Hong. Value analysis of two pairs and a half quantitative detection of hepatitis B[J]. 中国当代医药, 2021, 28(2): 149-151.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I2/149

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