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2018 Vol. 25, No. 15
Published: 2018-05-28
4
Influence factors of repeated induced abortion in unmarried women
HUANG Li-fang;XI Lu;LI Ya-wen;YI Yan-ping
Objective
To study the current situation and influencing factors of repeated induced abortion in unmarried women by investigation,and to explore strategies to reduce repeat induced abortion rate.
Methods
A total of 494 cases of unmarried women undergone induced abortion were investigated and tracked from June 2015 to May 2016 in our two hospitals.According to whether there were recurrent induced abortion in 1 years,they were divided into the repeated induced abortion group and the non repeated induced abortion group.The influence factors of repeated induced abortion were analyzed by variance analysis and multiple factors Logistic regression analysis.
Results
A total of 91 cases of recurrent abortion were found in unmarried women,with a ratio of 18.42%.There were statistically significant differences in occupation factor,education degree and knowledge of reproductive health compared with the two groups(P＜0.05).Multifactor Logistic regression analysis showed that the degree of education degree and reproductive health knowledge level were independent risk factors of repeated induced abortion,the difference was statistically significant(P＜0.05).
Conclusion
The incidence of repeated induced abortion is higher in unmarried women.The risk factors of repeated induced abortion are low education and low understanding of reproductive health.It is necessary to strengthen the publicity and education of the reproductive system of the population and reduce the rate of repeated induced abortion as far as possible.
2018 Vol. 25 (15): 4-7 [
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] (
181
)
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8
Study on comorbidity of Methamphetamine dependence and other mental disorders and related factors
DU Ying;TAN Chang-zan;LIU Qi;LUO Chang-zhou;LIANG Qi-sheng;LIANG Yan
Objective
To explore the comorbidity of Methamphetamine dependence and other mental disorders and the influence of related factors
.Methods
A total of 157 subjects with comorbidity Methamphetamine dependence and other mental disorders who were entrusted with psychiatric expertise were collected from Nanfeng Enforced Isolation DetoxificationInstituteofGuangdongProvinceandFamaleEnforcedIsolationDetoxificationInstituteHospitalofGuangdong Province from April 2016 to December 2017 were divided into male group(96 cases)and female group(61 cases).General information questionnaire and drug related factor questionnaire were made,all patients were investigated by DSM-Ⅳ-TR axisⅠ obstacle setting clinical examination version (DSM-Ⅳ-TR,SCID-Ⅰ).
Results
Male with methamphetamine dependence and other mental disorders were less educated,more unemployed,less annual income,and more detoxification times(P＜0.05).The positive family history of drug use was more common(P＜0.05),and higher incidence with comorbid manic episodes(P＜0.05).In female group,the incidence with comorbidity depression and anxiety was higher than that in male group (P＜0.05).Improper income was the main source of drug use in male group,as well as earned income in female group (P＜0.05).For the first time,the main reason for drug use was the pursuit of stimulation in male group,as well as to release negative emotions in female group (P＜0.05).
Conclusion
Comorbidity methamphetamine dependence and other mental disorders show differences between genders.Male methamphetamine dependent patients are more likely to relapse than that in female.Relapse prevention should attach importance to be the comorbidity problem.
2018 Vol. 25 (15): 8-11 [
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] (
175
)
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12
Correlation analysis between homocysteine,low density lipoprotein cholesterol and intracranial arterial stenosis
XIE Qiao;QIN Hao-qiang
Objective
To investigate the relationship between homocysteine plus low density lipoprotein levels and intracranial arterial stenosis in patients with ischemic stroke.
Methods
A total of 60 cases as observation group were selected from patients with ischemic stroke who were treated in department of neurology in our hospital from January 2013 to December 2014.Meanwhile,60 normal were selected as the control group at the same time.The blood samples were tested for homocysteine and low density lipoprotein.Head and neck CE-MRA weral e used to check the vascular condition of intracranial arteries.
Results
The blood homocysteine level in the observation group was(18.19±6.23)μmol/L,and wihch was higher than that in the control group([11.23±5.46] μmol/L)(P<0.05).The patients in,intracranial artery stenosis group were subdivided into light,medium and severe groups.The homocysteine level in severe stenosis group was statistically significant than that in other two groups(P<0.05).There was no statistical difference in LDL levels between three subgroups(P＞0.05).Homocysteine was positively correlated with the degree of cerebral vascular stenosis(r=0.68,P<0.05).Multiple regression analysis showed that hypertension and homocysteine levels were closely related to cerebrovascular stenosis.
Conclusion
Blood homocysteine and low density lipoprotein level both are risk factors for cerebral vascular stenosis,and high homocysteine is highly correlated with cerebral vascular stenosis.Prevention and intervention for high level of homocysteine should be timely considered to avoid the occurrence of ischemic cerebrovascular disease.
2018 Vol. 25 (15): 12-14转18 [
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181
)
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15
Application effect of Dexmedetomidine combined with Sevoflurane general anesthesia in the elderly patients with transurethral resection of the prostate
HE Shi-wu
Objective
To investigate the application effect of Dexmedetomidine combined with Sevoflurane general anesthesia in elderly patients undergoing transurethral resection of the prostate.
Methods
A total of 90 elderly patients who underwent transurethral resection of the prostate from January 2015 to December 2016 in our hospital were selected as subjects,and were divided into group 1,group 2,group 3 according to the random number table method,30 cases in each group.In group 1,Dexmedetomidine was pumped within 15 min and then pumped into physiological saline.In group 2,Dexmedetomidine was continuously pumped in.Group 3 was given physiological saline to continue pumping.The awakening time,the time of extraction of laryngeal mask,coverage time,operation time,anesthesia time,incidence of adverse reactions,incidence of POCD,and MMSE score,the level of HR,MAP,NF-κB and IL-1β at different times were compared between the three groups.
Results
There was no significant difference in the awakening time,the time of extraction of laryngeal mask,operation time,anesthesia time,and the incidence rate of adverse reaction between the three groups(P＞0.05).The MMSE score on the 3
rd
postoperative day in the group 1 and group 2 was higher than that in the group 3,the incidence rate of POCD in the group 1 and group 2 was lower than that in the group 3,the differences were statistically significant(P＜0.05).The level of HR and MAP in the group 1 and group 2 were lower than those in the group 3 at T
1
,T
3
,and T
4
,the difference was statistically significant(P＜0.05).The levels of NF-κB and IL-1β in group 1 and group 2 were lower than those in group 3 at t
1
,t
2
,and t
3
,and the differences were statistically significant(P＜0.05).
Conclusion
Selective Dexmedetomidine combined with Sevoflurane general anesthesia in patients undergoing transurethral resection of the prostate can make the blood pressure more stable,and which can significantly reduce the incidence of POCD and postoperative plasma inflammatory factors.
2018 Vol. 25 (15): 15-18 [
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177
)
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19
Clinical observation of preoperative biliary drainage before pancreatoduodenectomy for low malignant obstructive jaundice
XU Ma-chuan;XIE Wei;FENG Shi-jian;HE Guo-shai;CHEN Wan-mei
Objective
To observe the effect and incidence of complications of preoperative biliary drainage before pancreatoduodenectomy for low malignant obstructive jaundice.
Methods
The data of 78 patients with lower malignant obstructive jaundice who were treated from January to December 2017 in our hospital were collected.All the patients were treated with pancreatoduodenectomy and divided into two groups preoperatively according to whether preoperative biliary drainage was conducted or not.Among them,36 patients who were given preoperative biliary drainage were taken as biliary drainage group;while,42 case who were not given preoperative biliary drainage were taken as control group.The total bilirubin（TB）before and after preoperative biliary drainage of biliary drainage group was observed.The perioperative indicators，postoperative morbidity and mortality were compared between the two groups.
Results
The TB level of biliary drainage group before radical resection was（209.62±22.96）μmol/L，which was significantly lower than that before biliary drainage（[311.07±39.76]μmol/L）and that of the control group（[297.83±42.69]μmol/L）before radical resection，both with statistically significant difference（P<0.05）.The preoperative treatment duration and total treatment time of biliary drainage group were longer than those of control groups;and the allogenic erythrocyte infusion volume of biliary drainage group was less than that of control group，with statistically significant difference（P<0.05）.There was no statistically significant difference in the mean operation time，mean blood transfusion volume and postoperative hospital stay between the two groups（P＞0.05）.The incidence of complications and mortality rate of biliary drainage group were 61.11%and 0.00%versus control group′s 66.67%and 2.38%，respectively，without statistically significant difference（P＞0.05）.
Conclusion
Application of preoperative biliary drainage before pancreatoduodenectomy for low malignant obstructive jaundice can reduce the level of total bilirubin，but has no significant effect on the prognosis of patients.
2018 Vol. 25 (15): 19-21转25 [
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] (
176
)
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22
Research progress of Linezolid in ICU with Gram-positive coccus infection
GUO Jian
The ICU ward is the ward of offering the critical patients the comprehensive treatment and nursing interventions,and most of the patients are in critical condition.Due to the specificity of ICU ward,a few of patients will have the drug resistance during the long-term medication,among them,the infection rate of Gram-positive coccus is high.The difficulty of the clinical treatment will be increased as long as the ICU patients are associated with the Gram-positive coccus infection.Linezolid is the artificially synthesized oxazolidinone antibacterial agents,which it is commonly applied in Gram-positive coccus infection.This article reviews the research progress of Linezolid in ICU with Gram-positive coccus infection.
2018 Vol. 25 (15): 22-25 [
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] (
165
)
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26
Research progress of combined mutation of FLT3-ITD and DNMT3A R882 gene in acute myeloid leukemia
YANG Bin-ying
FLT3 mutation-internal tandem duplication (FLT3-ITD)mutation is a common type of mutation in acute myeloid leukemia (AML),which is closely related to the occurrence,development and poor prognosis of AML.DNA methylation transferase 3A (DNM-T3A)mutation has a high frequency in AML.About 60%DNMT3A mutations happened at codon R882.DNMT3A R882 mutation plays an important role in the development of AML,and suggests poor prognosis.In recent years,studies have found that FLT3-ITD and DNMT3A R882 mutations are both factors for poor prognosis of AML.Combined with the results of current research,this paper summarizes the pathogenesis,synergy,clinical characteri-stics,treatment and prognosis of combined mutation of FLT3-ITD and DNMT3A R882 in AML.
2018 Vol. 25 (15): 26-29 [
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224
)
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30
Analysis of the effect of family-based psychological intervention on recurrent spontaneous abortion
LIN Pei-xuan;QU Yan-xia;HUA Shi-wen;WU Hai-ying;GUI Yue-e;TANG Ying
Objective
To explore the management mode of family-based recurrent spontaneous abortion (RSA)and to provide an effective reference for clinical psychological intervention in the treatment of RSA.
Methods
A total of 150 RSA patients who visited Guangzhou Women′s and Children′s Medical Center from January 2016 to September 2017 were selected and randomly divided into control group and observation group,with 75 cases in each group.The control group adopted conventional intervention methods,and the observation group adopted family-based intervention model,the scores of self-rating depression scale and self-rating anxiety scale of patients in the two groups were compared,and the intervention effect was analyzed.
Results
Before intervention,the average scores of SAS and SDS in the two groups were significantly higher than those of normal people,and the differences were statistically significant(P<0.001).However,there was no statistical difference between SAS and SDS scores before intervention in the two groups(P>0.05).SAS and SDS scores of patients in the observation group were lower than those in the control group after intervention,and the differences were statistically significant(P<0.01).SAS and SDS scores of two groups of patients after intervention were lower than those before intervention,and the differences were statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).
Conclusion
The family-based intervention mode can evidently improve the mental health of RSV patients and successfully increase the total effective rate of pregnancy,which is worthy of extensive promotion.
2018 Vol. 25 (15): 30-33 [
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179
)
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34
Application of transfering the abdominal pedicle flap to lower iliac nerve in finger transplantation
LIU Wen-song;LI Ai-guo;CHEN Sheng-yang;JIA Yang;HE Wei;LIU jin-hai;ZHOU Fu-ming
Objective
To explore the application effect of transfering the abdominal pedicle flap to lower iliac nerve in finger transplantation.
Methods
Altogether 5 cases of finger broken between people with acute hand trauma in department of hand surgery of our hospital from October 2015 to December 2017,who were performed the grafting operation to transfer the abdominal pedicle flap to lower iliac nerve,ventral superficial vein and superficial iliac vein distantly.The postoperative follow-up was carried out to observe the recovery about nerve function.
Results
Through the observation of postoperative treatment,5 cases who were performed the grafting operation to transfer the abdominal pedicle flap to lower iliac nerve、ventral superficial vein and superficial iliac vein restored well and quickly.
Conclusion
The method of grafting operation to transfer the abdominal pedicle flap to lower iliac nerve distantly is safe,reliable and effective,which is worthy of clinical application.
2018 Vol. 25 (15): 34-36 [
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179
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37
Application effect of different temperature protection strategies on patients with surgical blood loss
TANG Chao-jun;CHEN Jin-hua;LI Fa-ren
Objective
To explore application effect of different temperature protection strategies on patients with surgical blood loss.
Methods
A total of 120 patients with surgical blood loss admitted to our hospital from August 2014 to August 2017 were selected and randomly divided into control group and observation group,with 60 cases in each group.Patients in the control group were covered with quilt for routine heat preservation,while patients in the observation group were treated with double-level heat preservation on the basis of the control group.The body temperature changes of two groups before operation(T
0
),during operation for 1 h(T
1
),after operation(T
2
)and after operation for 4 h(T
3
)were compared,and the postoperative recovery (waking time,extubation time,hospitalization time)and complications of two groups were compared
.Results
The body temperature of patients in observation group at T
0
and T
3
time points was(36.50±0.53)℃,(36.53±0.39)℃ respectively,and those of control group were(36.46±0.54)℃,(36.56±0.49)℃ respectively,there was no statistical difference between the two groups in the body temperature at the same time points(P>0.05).The time points of T
1
and T
2
in the observation group were (36.32±0.41)℃,(36.31±0.46)℃,and the body temperature of the observation group were significantly higher than those of the control group at the same time (35.62±0.45)℃,(35.66±0.42)℃,and the body temperature of the two groups at time points of T
1
and T
2
were significantly lower than that of T
0
in the same group (P<0.05).The postoperative indexes of wake-up time,extubation time and hospitalization time in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(P<0.05).The incidence of perioperative complications in the observation group was significantly lower than that in the control group(P<0.05).
Conclusion
Comprehensive temperature protection measures helps patients with surgical blood loss to maintain body temperature,reduce the amount of intraoperative blood loss,reduce the various complications caused by low temperatures,accelerate recovery time effectively.It is worth to be further promoted in clinic.
2018 Vol. 25 (15): 37-39 [
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159
)
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40
Effect comparison of laparoscopic cholecystectomy for the treatment of acute calculous cholecystitis at different operation timing
LI Wen-di;BAO Han-kang
Objective
To explore the results of laparoscopic cholecystectomy in the treatment of acute calculous cholecystitis at different operation times
.Methods
The data of 82 patients with acute calculous cholecystitis undergone laparoscopic resection in our hospital from February 2016 to February 2017 were retrospectively analyzed.They were grouped according to different surgical timings.In group A(n=44),the surgery was performed within 72 hours after onset,while in group B (n=38),the laparoscopic cholecystectomy was performed over 72 hours after onset.The therapeutic effect was analyzed.
Results
The postoperative exhaust time and average hospitalization time in group A were shorter than those in group B,the differences were statistically significant(P<0.05).The complication rates of patients in group A were lower than those in group B,and the difference was statistically significant(P<0.05).The conversion rate to laparotomy of patients in group A was(2.27%[1/44])lower than that in group B (15.79%[6/38]),and the difference was statistically significant(χ
2
=4.771,P=0.029<0.05).
Conclusion
For patients with acute calculous cholecystitis,performace of laparoscopic cholecystectomy within 72 hours of onset has advantages of few complications,high safety,promotion of postoperative recovery,and decrease of conversion to laparotomy rate.
2018 Vol. 25 (15): 40-42 [
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198
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43
Clinical efficacy and feasibility analysis of noninvasive ventilator assisted treatment for respiratory failure
ZHANG Jing-feng
Objective
To study the efficacy and feasibility of noninvasive ventilator assisted treatment for respiratory failure.
Methods
Sixty-eight patients with respiratory failure admitted to our hospital from June 2015 to June 2017 were selected,and their related clinical manifestations were reviewed.Thirty patients who were treated with conventional drugs were taken as the control group,and 38 patients who were treated with non-invasive ventilator as the observation group.By observing and comparing heart rate (P),breathing frequency(R),arterial blood oxygen partial pressure(PaO
2
),blood oxygen saturation (SPO
2
),arterial blood carbon dioxide partial pressure(PaCO
2
),forced vital capacity(FVC),forced breathing volume (FEV
1
)and FEV
1
%,the therapeutic effect and feasibility of the two groups were studied.
Results
After treatment,the indexes of P,R,and PaCO
2
in the observation group were significantly lower than those in the control group,while the indexes of PaO
2
and SPO
2
were significantly higher than those in the control group,with significant difference(P<0.05).Pulmonary function indexes of patients in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).
Conclusion
The non-invasive ventilator used in the treatment of respiratory failure,the treatment effect is good,and promote the rapid improvement of clinical symptoms,and significantly improve the treatment effect,suitable for popularization and application.
2018 Vol. 25 (15): 43-45 [
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] (
191
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46
Effects of peripheral blood immature granulocytes in the evaluation of severity and prognosis of sepsis
ZOU Yu-jun;JIANG Kang-wei;WU Chun-yan;ZHONG Sui-bin;YE Xian-qin
Objective
To investigate the effects of peripheral blood immature granulocytes in the evaluation of severity and prognosis of sepsis.
Methods
Blood samples of 60 patients with sepsis admitted to our hospital from January 2016 to September 2017 were selected for examination.According to the lung injury of sepsis patients,patients were divided into high-risk group(21 cases),middle-risk group(22 cases)and low-risk group(17 cases).Peripheral blood samples of three groups were tested for naive granulocytes,serum procalcitonin and C-reactive protein,and the differences between different risk levels and prognosis were analyzed.
Results
The peripheral blood naive granulocytes,serum procalcitonin and C-reactive protein of patients in high-danger group were higher than those in middle danger-risk group and low danger-risk group,the differences were statistically significant(P<0.05).The peripheral blood naive granulocytes,serum procalcitonin and C-reactive protein in death group were significantly higher than those in survival group,and the differences were statistically significant(P<0.05).
Conclusion
Peripheral blood immature granulocytes increase in number along with the increasing severity of sepsis.At the same time,it also has a positive effect on the prognosis evaluation for patients,which is recommended to be promoted in clinical practice.
2018 Vol. 25 (15): 46-48 [
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181
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49
Effect of Carbon Dioxide laser ablation and welding skin incision in the treatment of facial sebaceous cyst
LI Fu-chang
Objective
To investigate the clinical efficacy of Carbon Dioxide laser ablation and welding skin incision in the treatment of facial sebaceous cyst.
Methods
A total of 80 cases of facial sebaceous cyst complicated with infection and necrosis were selected from January 2016 to June 2017 in our hospital,and were divided into control group and observation group by random number table method,with 40 cases in each group.The observation group used KHC-H-1 Carbon Dioxide laser therapeutic apparatus provided by Wuhan Everbright Kang Medical Equipment Co.,Ltd.,the laser treatment wavelength was set to 600-700 nm,the spot diameter was 100-120 mm in the window,and the output power was over 3 W.Targeted irradiation treatment was carried out for sebaceous cyst lesions once a day for 15 min each time,and then skin incision was selected to be welded with carbon dioxide laser.The control group was treated by surgical resection under local anesthesia,and after operation,combined with human-like collagen dressing,the improvement time of clinical symptoms(redness and swelling subsided,wound healing and cyst disappeared)in two groups were compared,the results of skin properties measurement in two groups were measured,and the clinical treatment effects in two groups were statistically analyzed.
Results
The improvement time of clinical symptoms in the observation group was significantly earlier than that in the control group,and the difference was statistically significant(P<0.05).The test results of skin properties in the observation group were significantly better than those in the control group,and the differences were statistically significant(P<0.05).The total effective rate of patients in the observation group was significantly higher than that in the control group,and the difference was statistically significant(χ
2
=19.771,P=0.000<0.05).
Conclusion
For sebaceous cysts,the use of Carbon Dioxide laser ablation and welding skin incision treatment can effectively improve the surgical treatment effect,reduce postoperative scar formation and improve postoperative skin quality and quality,thereby improving the overall clinical therapeutic effect.
2018 Vol. 25 (15): 49-51 [
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173
)
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52
Comparison of the application value of multi-slice spiral CT and B-ultrasound in the diagnosis of emergency abdominal trauma
QIAO Ting;WEN Xue-hui;SONG Yang;DONG Zhi-hui
Objective
To compare and analyze the clinical effects of multi-slice spiral CT and B-ultrasound in the diagnosis of emergency abdominal trauma.
Methods
A total of 80 cases of abdominal trauma patients admitted to our hospital from January 2017 to January 2018 were selected for retrospective analysis.All subjects were examined by multislice spiral CT and B-ultrasound,and the diagnostic effects of the two methods were compared
.Results
There was no significant difference in the diagnostic results and the clinical coincidence rate of the two methods(P>0.05).There was no significant difference between the two examination methods in the classification of organ damage degree and the clinical coincidence rate(P>0.05).
Conclusion
B-ultrasound and multi-slice spiral CT examination have a high clinical value in the diagnosis of emergency abdominal trauma.In terms of detection rate,diagnosis of organ injury,and degree of injury,differences in multi-slice spiral CT and B-ultrasound are not significant.It is suggested that B-ultrasound be used as the preferred diagnostic method in clinical practice.When the patient's condition is complicated,multi-slice spiral CT can be used for combined diagnosis to increase the clinical diagnosis rate.
2018 Vol. 25 (15): 52-54 [
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] (
149
)
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55
Influence of urodynamics and sexual function of transurethral plasmakinetic enuc leation of the prostate in the treatment of prostatic hyperplasia
LIU Wen-gang;LI Jie;YE Zhao-yang;LI Ming;CHENG Yi;WU Zhi-rong
Objective
To investigate the influence of urodynamics and sexual function of transurethral plasmakinetic enucleation of the prostate in the treatment of prostatic hyperplasia(PKEP).
Methods
Eighty-five patients with prostatic hyperplasia admitted in our hospital from August 2012 to May 2017 were selected and divided into control group (n=42)and study group (n=43)according to different treatment methods.The control group was treated with transurethral bipolar plasma prostatectomy(PKRP),and the study group was treated with PKEP.The surgical indicators,urodynamics and functional changes of the two groups were retrospectively compared and analyzed.
Results
The operation time,indwelling time of urine tube and hospitalization time of patients in the study group were shorter than those in the control group,the intraoperative blood loss in the study group was less than that in the control group,and the differences were statistically significant(P<0.05).Before operation,there was no significant difference in urodynamics between the two groups(P>0.05).After operation,PVR in both groups was lower than that before operation,and Q
max
was higher than that before operation,PVR of patients in study group was lower than that of control group,Q
max
of patients in study group was larger than that of control group,and the differences were statistically significant(P<0.05).Before operation,there was no significant difference in sexual function between the two groups(P>0.05).After operation,the sexual function of patients in the control group was higher than that before operation,and that of patients in the study group was lower than that of the control group,with statistically significant difference (P<0.05).There was no statistically significant difference between the sexual function of patients in the study group and that before operation(P>0.05).The incidence of complications in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).
Conclusion
The short time of operation of prostatic hyperplasia,less bleeding and quick recovery after PKEP can effectively improve the urethral function of the patients,and have little adverse effect on the sexual function.
2018 Vol. 25 (15): 55-57转60 [
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] (
171
)
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58
The effect of vacuum sealing drainage technique in trauma patients with replantation of severed limb
LIU Xian-xin
Objective
To study the effect of the implementation of vacuum sealing drainage technique in trauma patients with replantation of severed limb
.Methods
A total of 100 cases of limb replantation patients admitted to our hospital from August 1
st
,2016 to December 2
nd
,2017 were selected,and divided into control group and observation group,with 50 cases in each group.The treatment of routine treatment and negative pressure closed drainage of trauma were respectively implemented,and the volume scores of primary and secondary symptoms,total integral values and total effective rates of the two groups of patients after treatment were compared.
Results
The volume scores and total scores of primary and secondary symptoms in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The total effective rate of patients in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).
Conclusion
Traumatic vacuum closure drainage technology has obvious effect for limb replantation,and can effectively improve the main symptom scores and total volume integral value,it is worthy of study.
2018 Vol. 25 (15): 58-60 [
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] (
127
)
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61
Comparison of clinical efficacy of Propylthiouracil and Methimazole in the treatment of hyperthyroidism
DENG Li-ping;WU Hong-mei; YUE You-wei
Objective
To analyze the clinical effects of Propylthiouracil and Methimazole in the treatment of hyperthyroidism
.Methods
A total of 80 hyperthyroidism patients admitted to our hospital from April 2015 to March 2016 were selected as research objects,and were divided into control group and research group by random number table method,with 40 cases in each group.The control group was treated with Propylthiouracil,while the study group was treated with Methylimidazole.The total effective rate,thyroid hormone indicators,clinical indicators,liver injury incidence,rash incidence and granulocyte damage rate of the two groups were compared.
Results
The total effective rate of patients in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05).The thyroid hormone index of patients in the study group was better than that of the control group,and the difference was statistically significant(P<0.05).The clinical indicators of patients in the study group were better than those in the control group,with statistical significance (P<0.05).The incidence of liver injury in the study group was lower than that in the control group,and the difference was statistically significant(χ
2
=12.462,P=0.000).There was no significant difference in the incidence of adverse reactions between the two group(χ
2
=0.857,P=0.355).
Conclusion
In the clinical treatment of patients with hyperthyroidism,both Propylthiouracil and Methimazole have a certain therapeutic effect,but the latter treatment effect is significantly higher than the former,the latter in improving the thyroid hormone index,clinical indicators are excellent in the former,it is worthy of clinical application.
2018 Vol. 25 (15): 61-63转67 [
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] (
198
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64
Clinical value of hysterectomy simultaneous bilateral salpingectomy excision in patients with benign uterine diseases
ZHONG Ju-hua;SU Chen-mei
Objective
To probe into the ovarian function and the occurrence of ovarian cancer of hysterectomy simultaneous bilateral salpingectomy excision in treatment of patients with benign uterine diseases.
Methods
Sixty-four patients with uterine benign diseases admitted to our hospital from July 2012 to February 2015 were randomly selected and ranked by parity.Odd patients served as the observation group and even patients served as the control group,with 32 cases in each group.Patients in the control group were treated with hysterectomy,while patients in the observation group were treated with hysterectomy and bilateral salpingectomy.The ovarian function indicators,basic operation situation and the occurrence of pelvic encapsulated hydrops and ovarian cancer within 36 months after follow-up were compared between the two groups.
Results
Compared with the preoperative level,the levels of follicle stimulating hormone(FSH)and luteinizing hormone(LH)in the two groups were significantly higher at 6 months after operation,and the difference of estradiol(E
2
)levels was statistically lower(P<0.05).However,there was no significant difference between the two groups in ovarian function indicators at the same time(P>0.05).There was no statistically significant difference between the two groups in basic operation conditions(P>0.05).After 36 months′follow-up,the incidence of pelvic encapsulated hydrops and ovarian cancer in the observation group was significantly lower than that in the control group,with statistically significant difference (P<0.05).
Conclusion
The hysterectomy simultaneous bilateral salpingectomy excision in treatment of benign uterine diseases are safe and feasible,which will not aggravate the ovarian function of patients,and will not affect postoperative recovery,and it has positive effect on reducing the risk of postoperative ovarian cancer.
2018 Vol. 25 (15): 64-67 [
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184
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68
Effect of Tramadol use to prevent and treat chills after cesarean section under combined spinal and epidural anesthesia
WU Dong-peng;ZHANG Yan-xiang;XIA Jing-hong
Objective
To investigate the effect of Tramadol on chills after cesarean section under combined spinal and epidural anesthesia for prevention and treatment.
Methods
The 100 women undergoing cesarean section who were admitted to our hospital from September 2015 to March 2017 were selected as study subjects and divided into observation group and control group with 50 cases in each group,according to random number table method.After cesarean section,Tramadol was injected intravenously in the observation group and not in the control group.The occurrence of postoperative shivering was compared between the two groups.
Results
At the end of the surgery,the incidence of chills in the two groups of women was not statistically different(P＞0.05).After 15 minutes of treatment,the chilling tremor of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions such as nausea,vomiting,drowsiness,and dyspnea between the two groups of maternal patients (P＞0.05).
Conclusion
Tramadol after cesarean section under combined spinal and epidural anesthesia can effectively prevent the occurrence of postoperative shivering,which is worthy of clinical application.
2018 Vol. 25 (15): 68-70 [
Abstract
] (
171
)
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71
The effect of Dexmedetomidine combined with Sufentanil in laparoscopic combined abdominal and vaginal hysterectomy
XIE Guo-qiang;CHEN Xiu-yu;HE Yong-xiao;WU Cai-yuan
Objective
To explore the effect of Dexmedetomidine combined with Sufentanil in laparoscopic combined hysterectomy
.Methods
A total of 120 patients with gynecological laparoscopic combined hysterectomy were selected as subjects in our hospital from June 2015 to June 2017.They were divided into control group(60 cases)and observation group(60 cases)according to the digital parity method.The control group was used Sufentanil drug for postoperative analgesia,and the observation group was combined with Dexmedetomidine for postoperative analgesia on the basis of the control group.Postoperative analgesia was compared between the two groups.
Results
At 2,4 and 6 hours after surgery,the VAS score of the observation group was lower than the control group,and the difference was statistically significant(P<0.05).At 2 hours after surgery,the RASS score of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions(5.00%)in postoperative observation group was lower than that in the control group(26.67%),and the difference was statistically significant(P<0.05).
Conclusion
For gynecological laparoscopic abdominal joint vaginal hysterectomy patients,clinical choice right beautifulmi on composite analgesia,the analgesic effect of satisfaction,significantly reduce postoperative 6 hours(faded)during the drugs of cardiovascular response.
2018 Vol. 25 (15): 71-73 [
Abstract
] (
185
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74
Effects of Methoxamine on the blood pressure and cardiac pump function in the patients undergoing non-cardiac surgery under general anesthesia
ZHA Wei-feng
Objective
To analyze the effects of Methoxamine on the blood pressure and cardiac pump function in the patients undergoing non-cardiac surgery under general anesthesia.
Methods
From July 2016 to July 2017,164 patients undergoing non-cardiac surgery under general anesthesia treated in our hospital were selected as the subjects.According to different methods of anesthesia,they were divided into control group (80 cases,micro-sustained pump of normal saline)and observation group(84 cases,micro-sustained pump of Methoxamine).The changes in blood pressure and cardiac pump function during the operation were observed in both groups
.Results
The systolic blood pressure in the observation group was higher than that in the control group of 2 min after induction,immediately after intubation,and 5 minutes after intubation,at 1 min after intubation,the systolic blood pressure in the observation group was lower than that in the control group,the differences were statistically significant(P<0.05).At 2 min after induction and 1 min after intubation,the diastolic blood pressure in the observation group was lower than that in the control group,5 min after intubation,the diastolic blood pressure in the observation group was higher than that in the control group,the differences were statistically significant (P<0.05).At 1,5,10 min after intubation,there were statistically significant differences in the changes of diastolic blood pressure and systolic blood pressure compared within the intubation (P<0.05).At 2 min after induction,the changes of LVEF and FS were compared in the observation group than in the control group,the differences were statistically significant(P<0.05).Immediately after intubation,the changes of LVEF and FS in the observation group were significantly different from those in the control group (P<0.05).At 1 minute after intubation,the changes of LVEF in the observation group was compared with that in the control group,and the difference was statistically significant(P<0.05).At 5 min and 10 min after intubation,there was no statistically significant difference in LVEF and FS between the control group and the observation group (P>0.05).At 1 min,5 min,and 10 min after intubation,the results of changes in LVEF and FS levels within each of the two groups were compared with the results immediately after intubation,the differences were statistically significant(P<0.05).
Conclusion
The application of methoxamine in the patients undergoing non-cardiac surgery under general anesthesia can maintain blood pressure stability and have minor effect on the cardiac pump function,which has a good application prospect in clinical anesthesia.
2018 Vol. 25 (15): 74-76转80 [
Abstract
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170
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77
Effect of low-dose Propofol combined with Tramadol for patients with chills after intraspinal anesthesia
YANG Qi-lin
Objective
To observe the effect of low-dose Propofol combined with Tramadol for patients with chills after intraspinal anesthesia.
Methods
A total of 100 patients with chills after intraspinal anesthesia from January 20,2016 to January 20,2017 in our hospital were selected as the subjects,and divided into control group (n=50)and observation group by computer random matching,50 cases in each group.In the control group,Tramadol was used,while in the observation group,low-dose Propofol combined with Tramadol was adopted.The mean arterial pressure(MAP),heart rate(HR),SpO
2
,chills grading,depth of sedation,total effectiveness rate,and recurrence were compared between the two groups.
Results
The MAP at 5,7,and 10 minutes after treatment in the observation group was lower than that of the control group(P<0.05).The HR and SpO
2
at 5,7,and 10 minutes after administration in the observation group were not greatly different compared with those in the control group(P>0.05).There was no significant difference in chills grading between the observation group and the control group(P>0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).The depth of sedation in the observation group was not significantly different from that in the control group (P＞0.05).The total effectiveness rate of chills was higher in the observation group than the control group (P<0.05).The recurrence rate of the patients in the observation group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).
Conclusion
The use of low-dose propofol combined with tramadol via intraspinal anesthesia obtains a remarkable effect on treating chills,it can also improve the hemodynamic parameters,which is worthy of research.
2018 Vol. 25 (15): 77-80 [
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188
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81
The clinical effect of Amisulpride combined with low dose of Aripiprazole in the treatment of schizophrenia and influence on serum prolactin in patients
HUANG Shi-qing;LIU Zhi-ling;ZHU Jin-cai;DING Wan-mei;LIU Li-fang
Objective
To investigate the efficacy,adverse reactions,and effects of prolactin on Amisulpride in combination with low-dose Aripiprazole in the treatment of schizophrenia.
Methods
Eighty patients with schizophrenia treated in our hospital from November 2016 to October 2017 were selected as study subjects.According to the random number table method,patients were divided into study group(n=40)and control group(n=40).The patients in the study group were given Amisulpride in combination with low-dose Aripiprazole and the patients in the control group were given Amisulpride.The scores of positive and negative syndrome scale (PANSS),total effective rates,treatment emergent symptom scale(TESS)scores and blood prolactin levels of the two groups were compared before and after 8 weeks of treatment
.Results
After 8 weeks of treatment,the total PANSS score in the study group was(38.8±20.2)points,and the total PANSS score in the control group was(39.7±20.7)points,there was no significant difference in the total PANSS scores between the two groups after treatment(P>0.05),and the positive symptoms,negative symptoms and psychopathological scores of the two groups were also not statistically significant(P>0.05).The total effective rate was 92.5%in the study group and 90.0%in the control group,there was no significant difference between the two groups in the total effective rate(P>0.05).The incidence of adverse reactions was 22.50%and the TESS score was(7.22±4.12)points in the study group,while the incidence of adverse reactions was 25.00%and the TESS score was(7.31±4.06)points in the control group.The adverse reaction rate and TESS score of the two groups were not statistically significant(P>0.05).The PRL in the study group was(23.23±13.12)μg/ml,which was significantly lower than that in the control group of(55.25±13.15)μg/ml,the difference was statistically significant(P<0.05).
Conclusions
The combination of low-dose Aripiprazole does not affect the efficacy of Amisulpride,but significantly improves hyperprolactinemia due to Amisulpride,and does not exacerbate adverse reactions.
2018 Vol. 25 (15): 81-83转87 [
Abstract
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196
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84
Effects of Baixian Xiatare Tablets in the adjuvant treatment of acne
LI Bo-pei;LAN Shu-ting
Objective
To investigate the effects of Baixian Xitare Tablets in the adjuvant treatment of acne and its repair effect of skin barrier function in patients
.Methods
A total of 100 patients with acne treated in People′s Hospital of Fogang County from July 2016 to July 2017 were selected as the research subjects.They were divided into two groups by the envelope random grouping method,50 cases in each group.The patients in the control group were treated with red and blue light radiation.The patients in the observation group were further given Baixian Xiatare Tablets based on the control group.The clinical symptom scores,treatment safety,total efficacy,skin oils and epidermal water loss(TEWL)were compared between the two groups
.Results
The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The types of skin lesions,number of skin lesions,flushing and burning score were of the observation group were all lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of skin oil,TEWL and adverse reactions in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).
Conclusion
Baixian Xiatare Tablets for the patients with acne can reduce the incidence rate of adverse reactions,improve flushing,skin lesions and other symptoms,improve the overall efficacy,and improve skin oils and TEWL.
2018 Vol. 25 (15): 84-87 [
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] (
178
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88
Analysis of clinical effect and safety of Compound Polymyxin B Ointment combined with Adapalene Gel in treatment of acne vulgaris
LIU Yu-qian;LAI Yong-hui; WEN Li-zhang;YANG Fan;PAN Peng;MO Yan-shi;LUO Bin
Objective
To study and analyze the clinical effects and safety of Compound Polymyxin B Ointment combined with Adapalene Gel in treatment of acne vulgaris
.Methods
A total of 128 cases of patients with acne vulgaris who treated in our hospital from January 2016 to August 2017 were selected as subjects,and were divided into the observation group and the control group according to the random number grouping method,with 64 cases in each group.The patients in the control group were treated with only Compound Polymyxin B Ointment,while the patients in the observation group were treated with Compound Polymyxin B Ointment combined with Adapalene Gel.The effects,the occurrence of adverse reactions and the skin lesions counts after treatment of patients between the two groups were observed
.Results
The total effective rate of the patients in the observation group was 98.44%,which was significantly higher than that in the control group of 87.50%,the difference was statistically significant(P<0.05).The total incidence of adverse reaction in the observation group was 9.38%,which was significantly lower than that in the control group of 21.88%,the difference was statistically significant(P<0.05).The skin lesions(papule,comedo,pimple)counts of the patients in the observation group were less than those of the control group,and the differences were statistically significant(P<0.05).
Conclusion
The effect of Compound Polymyxin B Ointment combined with Adapalene Gel in treatment of acne vulgaris are significant,which greatly reduce the patients′skin lesion counts,promotes the recovery of the patient,and it have high safety,thus it is worth promoting and using in clinical.
2018 Vol. 25 (15): 88-90 [
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172
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91
Application effect of targeted pharmacological guidance in the patients with diabetes mellitus
ZHI Yuan
Objective
To explore the application effect of targeted pharmacological guidance in the patients with diabetes mellitus.
Methods
A total of 138 patients with diabetes who were admitted to our hospital from March 2016 to March 2017 were divided into experimental group and control group according to the order of admission,with 69 patients in each group.Patients in the control group were given routine medication instructions.Patients in the experimental group were given scientific and comprehensive targeted pharmacological guidance.The intervention period was 6 months.The FPG,HbA1c,P 2 hBG levels,medication compliance and quality of life were compared between the two groups before and after intervention.
Results
There was no significant difference in FPG,HbA1c and P2 hBG levels before intervention between the two groups(P>0.05).After intervention,the FPG,HbA1c,and P 2 h BG levels in the experimental group were all lower than those in the control group and before intervention,the differences were statistically significant(P<0.05).The total medication compliance in the experimental group(95.65%)was higher than that in the control group(85.51%),and the difference was statistically significant(P<0.05).The excellent and good rate of the quality of life in the patients in the experimental group(94.20%)was higher than that in the control group(82.61%),and the difference was statistically significant(P<0.05).
Conclusion
Scientific and comprehensive targeted pharmacological guidance for the patients with diabetes can improve medication compliance,improve blood glucose control,and reduce the impact of disease on the quality of life of patients.
2018 Vol. 25 (15): 91-93转97 [
Abstract
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141
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94
The result analyzing of treatment superficial gastritis patients by Rebamipide combined with Rabeprazole
HUANG Jia-min;HUANG Zhi-xiong
Objective
To approach result of treatment superficial gastritis patients by Rebamipide combined with Rabeprazole.
Methods
The 200 cases clinical data of diagnosising and treat superficial gastritis patients in our hospital outpatient service from January 2016 to July 2017 were analyzed,which were divided into two group by different treatment method,which were control group (Rabeprazole treatment,100 cases)and detection group (Rebamipide combined with Rabeprazole treatment,100 cases).The IL-2,IL-4,IL-8,TGF-β,IL-17,IL-25,SOD,MDA levels of two group patients before treatment and after treatment were detected,the clinical treatment total effects rate of two group patients were detected.
Results
The IL-2,IL-4,IL-8,TGF-β,IL-17,IL-25,SOD,MDA levels of two group patients before treatment were no difference (P＞0.05),the IL-2,SOD of two group after treatment were higher than before treatment,IL-4,IL-8,TGF-,IL-17,IL-25,MDA levels were lower than before treatment,the IL-2,SOD of detection group after treatment were higher than control group,IL-4,IL-8,TGF-β,IL-17,IL-25,MDA levels were lower than control group,the clinical treatment total effects rate of detection group was higher than control group,the differences were statistical significance(P<0.05).
Conclusion
The treatment superficial gastritis patients by Rebamipide combined with Rabeprazole,which could improve inflammatory indicators,the result is good,it is worth to be used.
2018 Vol. 25 (15): 94-97 [
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148
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98
Clinical analysis of 263 cases of drug induced liver injury
SONG Wen-xia CHENG Ming-jian;OU Zhong-shun;ZHONG Tian-wen;ZHANG Qing-shang;JIANG Zhi-feng
Objective
To explore the clinical features and regular patterns of drug induced liver injury(DILI)in order to provide reference for DILI prevention and clinical medication.
Methods
All cases of drug induced liver injury from January 2014 to December 2017 were analyzed retrospectively.
Results
A total of 236 cases were chosen from 376 cases of DILI by the Roussel Uclaf Causality Assessment Method (RUCAM).Of 236 cases,there were 3 cases(1.27%)happened in 0-19 years old，35 cases(14.83%)happened in 20-39 years old,111 cases(47.03%)happened in 40-59 years old,70 cases(29.66%)happened in 60-79 years old,and 17 cases(7.20%)happened over 80 years old.The median of intake duration of the involving drugs was 20 days.Most of the involving drugs were anti-tumor drugs(30.08%),anti-infective drugs(29.66%)and traditional Chinese medicine(10.59%).
Conclusions
The most common drugs induced DILI are anti-tumor drugs,anti-infective drugs and traditional Chinese medicine.Clinical manifestations of DILI are deficient in specificity.It is important that the diagnosis and treatment procedures of DILI need laboratory examination,individualized pharmaceutical care,adverse drug reactions and monitoring.And it also should be payed more attention on the clinical application of large databases.
2018 Vol. 25 (15): 98-101 [
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136
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102
Effect of auxiliary treatment of Alprostadil in the hepatitis B cirrhosis and its influence on serum inflammatory factors
ZHU Ke-wei;XIAO Can-hui;BAI Yu-yan;PING Qu
Objective
To investigate the effect of auxiliary treatment of Alprostadil in the hepatitis B cirrhosis and its influence on serum inflammatory factors.
Methods
A total of 80 patients with hepatitis B cirrhosis admitted to our hospital from June 2016 to June 2017 were divided into group A (n=40)and group B (n=40)according to systic randomazition method.Group A was treated with Telbivudine on the basis of conventional treatment,group B was given Alprostadil for auxiliary treatment on the basis of group A.The clinical efficacy of the two groups of patients after 3 months of treatment,the hepatitis B virus DNA level and the inflammatory factors levels including interleukin-6(IL-6),interleukin-22(IL-22)and high-sensitivity C reactive protein(hs-CRP)before and after treatment were compared.
Results
The total effective rate in group B(90.00%)was higher than that in group A(67.50%),with statistically significant difference (P<0.05).The levels of HBV DNA after treatment in both groups were lower than those before treatment,but there was no significant difference between the two groups (P＞0.05).The levels of hs-CRP,IL-6 and IL-22 in two groups after treatment were lower than those before treatment,and the above indexes in group B were lower than those in group A,with statistically significant difference(P<0.05).
Conclusion
Alprostadil has a good adjuvant therapy for patients with hepatitis B cirrhosis,which can effectively control the DNA level of hepatitis B virus and the levels of inflammatory cytokines such as hs-CRP,IL-6 and IL-22.
2018 Vol. 25 (15): 102-104 [
Abstract
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147
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105
Efficacy of Montelukast Sodium combined with Budesonide and Ipratropium Bromide in the treatment of cough after infantile infection
KAN Yu-fang;CHENG Jun;LI Feng-qin
Objective
To investigate the clinical effect of Montelukast Sodium combined with Budesonide and Ipratropium Bromide nebulization in the treatment of infantile cough after infection.
Methods
A total of 68 children with cough after infection in our hospital from January 2016 to December 2017 were selected as the observation subjects,they were divided into two groups according to random number table method,namely,the control group (n=34),experimental group (n=34).The patients in the control group were given Montelukast Sodium orally,and those in the experimental group were treated with Budesonide and Ipratropium Bromide atomization inhalation on the basis of the control group.The clinical curative effect,improvement of symptoms and the adverse reaction rates were compared statistically.
Results
The clinical total effective rate of the experimental group was significantly higher than that of the control group.The data were 94.12%and 76.47%,and the difference was statistically significant(P＜0.05）.After treatment,the scores of cough and sleep in the experimental group were significantly lower than that in the control group,and the differences were statistically significant(P＜0.05）.The incidence of adverse reactions in the experimental group was 5.88%,and the incidence of adverse reactions in the control group was 2.94%,and the difference was not statistically significant(P＞0.05）.
Conclusion
The clinical effect of Montelukast Sodium combined with Budesonide and Ipratropium Bromide atomization inhalation is more accurate.It can effectively improve the quality of cough and sleep in children with safe and reliable characteristics.
2018 Vol. 25 (15): 105-107 [
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130
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108
Effect of Nourishing Kidney and Strengthening Bone Decoction treating osteoporosis in the elderly through transdermal drug delivery by supersonic conductance rapid infiltration
WANG Xin-jie;SUN Xiu-liang;CHEN Hui;YUAN Sheng-ping;LIN Wang-de
Objective
To observe the effect of Nourishing Kidney and Strengthening Bone Decoction treating osteoporosis in the elderly through transdermal drug delivery by supersonic conductance rapid infiltration.
Methods
A total of 100 patients diagnosed as osteoporosis in department of orthopedics of our hospital form June 2015 to June 2017 were randomly divided into the control group and the treatment group,and there were 50 cases in each group.The control group was treated with Calcium Lactate of 500 mg,3 times a day and 10 d were 1 course.The treatment group was treated with Nourishing Kidney and Strengthening Bone Decoction through transdermal drug delivery by supersonic conductance rapid infiltration,30 min each time,1 time a day,and 10 d were 1 course.
Results
The total effective rate was 94%in the treatment group and it was 66%in the control group,and the difference between the two groups was statistically significant(P<0.05).T value of BMD of lumbar L
2～4
in the treatment group was 0.59±3.77,while that in the control group was-1.43±1.53,and the difference between the two groups was statistically significant(P<0.05).
Conclusion
The effect of Nourishing Kidney and Strengthening Bone Decoction treating osteoporosis in the elderly is reliable.
2018 Vol. 25 (15): 108-110 [
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137
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111
Effect of electroacupuncture combined with auricular point sticking treating dysphagia after cerebral apoplexy
DENG Yun;SHE Xiao-jing
Objective
To explore the clinical effect of electroacupuncture combined with auricular point sticking treating dysphagia after cerebral apoplexy.
Methods
One hundred patients with dysphagia after cerebral apoplexy from Foshan Hospital of TCM,Chancheng National Hi-Tech Industrial Development Zone Branch from January 2015 to July 2017 were selected and they were randomly divided into the treatment group (50 cases)and control group (50 cases).The control group received swallowing function training while the treatment group received swallowing function training and electroacupuncture combined with auricular point sticking.SAS score,SDS score,water swallowing test(WST)score,stroke specific quality of life scale (SS-QOL)score and the total effective rate were compared before and after treatment between the two groups
.Results
After 1 months treatment,the score of SAS,SDS and WST in the two groups were significantly lower than those before treatment(P<0.05),and the decrease of the treatment group was more obvious,and the differences were statistically significantcompared with the control group(P<0.05).After 1 months treatment,SS-QOL score of the two groups were higher than those before treatment(P<0.05),and the increase of the treatment group was obvious compared with the control group(P<0.05).The total rate in the treatment group was 84.00%,which was significantly higher than that in the control group(66.00%)(P<0.05).
Conclousion
Electroacupuncture combined with auricular point sticking can effectively improve swallowing function,reduce negative emotions and improve the quality of life of patients with stroke,which is worthy of clinical application and promotion.
2018 Vol. 25 (15): 111-113转119 [
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152
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114
Efficacy of antihypertensive point acupoint in treating hypertension of liver-yang hypertension
YANG Yong-hua;QIN Chun-mei;HUANG Chun-yan
Objective
To evaluate the clinical effect of acupoint sticking of antihypertensive therapy on liver-yang hyperactivity hypertension.
Methods
A total of 120 patients with primary hypertension of liver-yang hyperactivity were enrolled in this study from September 2016 to November 2017 at our hospital.All the patients were randomly divided into the observation group (n=60)and the control group (n=60).Patients in the control group were given standardized anti-hpertension treatment,and patients in the observation group were given anti-hypertension treatment combined with acpoint sticking thapy.on the basic treatment.The changes of blood pressure,symptoms and microalbuminuria were compared between the two groups.
Results
The anti-hypertension efficacy of the observation group was 100.0%,which was significantly higher than that of the control group(75.0%)(P<0.05).The improvement of microalbuminuria in the observation group was obviously better than that in the control group (73.3%vs.5.0%)(P<0.05).In addition,the efficacy of symptom improvement in the observation group was 97.1%,which was significantly better than that of the control group(56.3%)(P<0.05).Among them,the improvement of clinical symptoms in the observation group,including dizziness,dry mouth,constipation,irritability,insomnia and forgetfulness,and sore waist and knee was 100.0%,87.5%，100.0%,94.7%and 91.7%,respectively,which were all better than those in the control group(86.2%,7.7%,76.9%，11.8%and 2.0%)(P<0.05).
Conclusion
The antihypertensive formula of acupoint application can reduce the blood pressure,microalbuminuria,and improve the clinical symptoms more effectively,including dizziness,dry mouth constipation,irritability,insomnia and forgetfulness,and sore and knee in patients with liver-yang hyperactivity hypertension.
2018 Vol. 25 (15): 114-116 [
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151
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Therapeutic effects of herbal fumigation treatment in the heel pain symptoms
ZHANG Wen-tao
Objective
To study and analyze the feasibility of applying traditional Chinese medicine fumigation in the treatment of heel pain.
Methods
A total of 126 patients with heel pain who were admitted to our hospital from January 2015 to January 2018 were randomly divided into observation group and control group,63 cases in each group.The control group were took oral anti-inflammatory and analgesic drugs in combination with local blocking therapy.On this basis,the observation group was took Chinese herbal fumigation and washing method.The pain (VAS)scores,treatment effects,and satisfaction levels before and after treatment were compared between the two groups.
Results
Before treatment,there was no significant difference in VAS scores between the two groups (P＞0.05).After treatment,the VAS scores in the observation group were lower than those in the control group(P<0.05).The total effective rate of treatment in the observation group was 96.83%,which was higher than 79.37%in the control group,the difference was statistically significant(P<0.05).The total satisfaction of treatment in the observation group was 98.41%,which was higher than the 82.54%in the control group,the difference was statistically significant(P<0.05).
Conclusion
The effect of traditional Chinese medicine fumigation on the treatment of heel pain is very significant.It not only can effectively relieve the symptoms of patients with heel pain,but also can promote high satisfaction.Therefore,it is highly feasible and worthy of popularization and application.
2018 Vol. 25 (15): 117-119 [
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159
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Serum level of Heparin binding protein of pyohemia cases and the clinical significance
YANG Lu-bo;QIU Shu-yan;ZOU Yan-hua;MA Ling-di;HE Xiao-qing;WANG Jian
Objective
To observe serum level of Heparin binding protein (HBP)of cases with pyohemia and investigate the clinical significance
.Methods
From June 2016 to November 2017,55 cases with pyohemia from intensive care unit of my hospital were selected as pyohemia group,and 50 healthy cases were chosen as control group by physical examination.Serum levels of HBP,C-reactive protein(CRP),and procalcitonin(PCT)of both groups were compared.Serum levels of HBP,CRP,and PCT were compared in ordinary type pyohemia and serious type pyohemia at 2 days after admitted to hospital.Serum levels of HBP,CRP,and PCT were compared in survival group and dead group of pyohemia at 2 days after admitted to hospital.
Results
Serum levels of HBP([67.31±7.40]ng/ml),CRP([90.21±10.45]mg/l),and PCT([15.41±2.04]ng/ml)of pyohemia cases were evidently higher than control group(P<0.01).Serum levels of HBP([113.13±12.67]ng/ml),CRP ([146.96±16.12]mg/L),and PCT ([27.44±3.95]ng/ml)of serious type pyohemia cases were obviously higher than those of ordinary type pyohemia(P<0.01).Serum levels of HBP([125.65±14.33]ng/ml),CRP([150.35±16.78]mg/L),and PCT([29.31±3.13]ng/ml)of death group were obviously higher than those of survival group(P<0.01).
Conclusion
Serum level of HBP of cases with pyohemia is obviously increased,and may be one of effective indexes evaluating severity and prognosis of cases with pyohemia.
2018 Vol. 25 (15): 120-122转126 [
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175
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Application of loop-mediated isothermal amplification for the detection of mycobacterium tuberculosis
DU Wei-qin;XUE Ting;WANG Gui-qin
Objective
To establish the loop-mediated isothermal amplification technique (LAMP)for the detection of Mycobacterium tuberculosis(MTB)gene in the sputum of patients with pulmonary tuberculosis.
Methods
Three pairs of specific primers were designed based on highly conserved 16S rDNA of MTB as the target gene.From January 2017 to December 2017,89 sputum samples from the patients were with clinically diagnosed pulmonary tuberculosis,20 sputum samples from non-tuberculosis patients and the MTB standard strain(H37RV)were collected.LAMP method was established,and its specificity and sensitivity were tested.The MTB culture results were taken as the gold standard.SPSS13.0 was used for data processing and statistical analysis.
Results
LAMP was successfully established for the detection of MTB in the sputum.Its specificity was 100%and its sensitivity was 50 copies.In the clinical sputum testing,the specificity and sensitivity were 85%and 96.63%respectively.The results were almost identical with those of the MTB culture,the difference was statistically significant(P>0.05).
Conclusion
LAMP has high specificity and high sensitivity in the detection of MTB,which is suitable for the rapid detection of MTB in primary medical institutions.
2018 Vol. 25 (15): 123-126 [
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129
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127
Correlation analysis of serum amyloid A,heparin binding protein and the severity of sepsis
LI Shou-wei
Objective
To explore the correlation between serum amyloid A(SAA),heparin binding protein(HBP)and the severity of sepsis.
Methods
120 cases of patients with sepsis who treated in our hospital from November 2015 to January 2018 were selected as the case group,and they were divided into the sepsis group (48 cases),the severe sepsis group(40 cases)and the septic shock group(32 cases)according to the severity degree of the disease.At the same time,40 cases of health examination in our hospital were selected as the control group.The levels of SAA and HBP in the each group were compared and the correlation with the severity of sepsis was analyzed
.Results
The levels of serum SAA and HBP in the case group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of serum SAA and HBP in the severe sepsis group and the septic shock group were higher than those in the sepsis group,and the differences were statistically significant(P<0.05).The levels of serum SAA and HBP in the septic shock group were higher than those in the severe sepsis group,and the differences were statistically significant(P<0.05).Pearson correlation analysis showed that serum SAA and HBP were positively correlated with the severity of sepsis (r=0.752,0.794,P<0.05).
Conclusion
The serum levels of SAA and HBP are positively correlated with the severity of sepsis.The level of serum SAA and HBP are closely monitored in patients with sepsis which can be used to understand the severity of sepsis,and it is worthy of clinical promotion and application.
2018 Vol. 25 (15): 127-129 [
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143
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130
Discussion on reexamination rules for the combined detection of GEB-800 urine dry chemical analyzer and UF-1000i urine tangible component analyzer for urine specimen
WANG Yu
Objective
To establish and evaluate the reexamination rules for the combined detection of GEB-800 urine dry chemical analyzer and UF-1000i urine tangible component analyzer for urine specimen.
Methods
A total of 1000 urine samples from the hospital of Civil Aviation Flight University of China in March 2018 were collected for study.GEB-800 urine dry chemistry analyzer and UF-1000i urine tangible component analyzer were used to detect the dry chemistry markers and urine visible components,respectively.The doubly blind method was used for the reexamination of centrifuge microscope,and the mean values of the microscopic examination results were used as the criterion.Three schemes were designed for optimization of reexamination rules.Scheme 1：any positive result of leukocyte esterase(LEU),occult blood (BLD),nitrite (NIT),protein (Pro)by urine dry chemical analyzer.Scheme 2：the urine tangible component analysis any index of leucocyte(WBC),red blood cell(RBC),tube type(Cast)exceeded the upper limit of the reference interval.Scheme 3：urine dry chemical detection results of LEU,BLD,NIT and Pro were not consistent with the results of urinary sediment analysis of WBC,RBC,and Cast.
Results
Using the microscope results as the standard,in the 1000 cases of urine samples for establishment of reexamination rules,the total positive rate accounted for 39.5%(395/1000),and that of RBC,WBC,Pro and Cast was 18.2%(182/1000),10.6%(106/1000),9.2%(92/1000),1.5%(15/1 000),respectively.Among them,the true positive rate of the reexamination scheme 3 was 95.5%,the false negative rate was 4.5%,the true negative rate was 74.2%,the false positive rate was 25.8%,the reexamination rate is 22.4%,and the coincidence rate is 82.8%.
Conclusion
The optimal reexamination rule of combined detection by GEB-800 urine dry chemistry analyzer and UF-1000i urine tangible component analyzer is that urine dry chemical detection results of LEU,BLD,NIT and Pro are not consistent with the results of urinary sediment analysis of WBC,RBC and Cast.
2018 Vol. 25 (15): 130-132 [
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146
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133
Application of Tort Liability Law in standardization of the responsibility and risk of medical record management
LIU Hong-wei;LIAO Yu-hong;LIAO Hong-xia
With the social development,people′s legal consciousness has been constantly improved,especially after the introduction of Tort Liability Law.The situation of a medical institution as a defendant has become a norm.In addition to the tort of diagnosis and treatment behavior,the cases of infringement caused by mismanagement of medical records also occur,such as the authenticity in the forming of medical records,the timeliness in preservation,legitimacy in usage and privacy protection of medical records,which makes the management of medical institutions more confused.This paper describes the relevant legal provisions of Tort Liability Law about medical record management,combined with related tort cases in our hospital in recent years in the medical record management process,analyzes and indicates the great progress and standardization of medical institutions in management in accordance with the law.However,part of the medical staff do not pay enough attention to the management of medical records,resulting in infringement behavior of medical institutions in the medical record management process，which makes medical institutions confronted with potential risks.With the application of Tort Liability Law in regulation of medical record management,medical institutions can make the management work more legitimate and standardized and improve the comprehensive management level,so as to protect the lawful rights and interests of both doctors and patients,which is worthy of promotion in the whole medical system.
2018 Vol. 25 (15): 133-135转142 [
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122
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136
The study on innovation of party building in public hospitals in the new era
WANG Ying-ying
Since the 19
th
National Congress of the Communist Party of China,China has entered a new era of socialism with Chinese characteristics.In the new era,it was of great historical significance and practical guiding value to improve party building work in public hospitals by the theory innovation.According to new needs and new tasks in the party building work and reform of public hospitals,this article analyzed the major present problems and discussed the innovation path and solution in depth.
2018 Vol. 25 (15): 136-139 [
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114
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140
Application effect of self management in patients with hypertension
CHEN Dong;ZOU Fa-zhi;LUO Hua-bing;YE Xue-mei
Objective
To probe into the effect of self management on blood pressure in patients with hypertension.
Methods
A total of 190 hypertensive patients managed by our center from January 2013 to January 2016 were selected and divided into control group(n=90)and study group(n=100)by intervention method.Patients in the control group were given routine health guidance,medication guidance and matters needing attention related to diseases,and were instructed to arrange their daily life and dietary habits reasonably and normally.Patients in the study group were intervened by self management model during treatment,and blood pressure control and health status of patients in the two groups were evaluated before and after the intervention.
Results
There was no significant difference in blood pressure indicators between the two groups before intervention(P>0.05).After the intervention,the blood pressure indicators of the two groups were significantly decreased,and the blood pressure indicators of the study group were significantly lower than those of the control group,the differences were statistically significant(P<0.05).There was no significant difference in the scores of health status between the two groups before intervention(P>0.05).After the intervention,the health status scores of the two groups of patients were significantly increased,and the health status scores of patients in the study group were significantly higher than those in the control group,with statistical significance (P<0.05).
Conclusion
The self management of patients with hypertensive which can significantly improve the health of the patients,and can effective control of blood pressure,thus it have high application and promotion significance for patients with hypertension.
2018 Vol. 25 (15): 140-142 [
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156
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143
Application effect of self-managed health education in patients with rheumatoid arthritis
YU Jin;WU Rui;HU Rong;XIONG Wei;CHEN Jiao;XU Xiao-ting;ZHANG Mei-zhen;LI Hui;CHEN Li-ming
Objective
To explore the effect of self-managed health education in patients with rheumatoid arthritis(RA).
Methods
Ninety RA patients admitted to our hospital from January 2015 to December 2016 were selected as research objects,and were divided into study group and control group by random number table method,with 45 cases in each group.The study group received routine treatment and self-management health education intervention methods,while the control group received routine treatment and general guidance intervention methods.Seven self-management scores,joint swelling number(SJC),joint tenderness number(TJC),morning stiffness time and average grip strength of both hands,as well as the incidence of adverse events during hospitalization and one year follow-up were compared between the two groups after intervention (one year follow-up).
Results
The self-management scores of patients in the study group were significantly higher than those in the control group after intervention,and the difference was statistically significant(P<0.05).After intervention,the average grip strength of the patients in the study group was significantly higher than that of the control group,and the morning stiffness time was shorter than that of the control group,and SJC and TJC were significantly lower than that of the control group,with significant difference(P<0.05).The total incidence of adverse events in the study group was significantly lower than that in the control group(P<0.05),and the incidence of falls outside the hospital in the study group was significantly lower than that in the control group,with statistically significant difference(P<0.05).
Conclusion
The self-management health education can significantly enhance the self-management consciousness of RA patients,improve the joint functional states of the whole body and reduce the incidence of adverse events,which is worth promoting.
2018 Vol. 25 (15): 143-146 [
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143
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147
The value of nursing intervention in the early diagnosis of neonatal sepsis with tissue factor pathway inhibitors and procalcitonin
DENG Dong-mei
Objective
To analyze the value of nursing intervention in the early diagnosis of neonatal sepsis with tissue factor pathway inhibitors(TFPI)and procalcitonin.
Methods
A total of 120 children with septicemia in our hospital were selected from January 2015 to December 2016.These participants were equally divided into two groups：observation group and control group by computer randomization,60 cases in each group.In the two groups,TFPI combined procalcitonin was performed for diagnosis.In the observation group,nursing intervention in the process of diagnosis was adopted,while in the control group,routine care was used.The improvement time of symptoms,hospital stay,satisfaction,and performance score in the two groups were compared.
Results
The score of performance in the observation group was higher than that in the control group (P<0.05).The improvement time of symptoms and hospital stay in the observation group were shorter than compared with those in the control group,which were displayed statistical significance(P<0.05).Satisfaction of the observation group was higher than that of the control group with a significant difference(P<0.05).
Conclusion
In the process of the implementation of TFPI combined with procalcitonin for the early diagnosis of children with sepsis,nursing intervention obtains a remarkable effect.
2018 Vol. 25 (15): 147-149 [
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159
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150
Influence study of nursing intervention on knowledge，behavior and biochemical indicators of blood glucose monitoring in diabetics based on the theory of protection motivation
LI Fang
Objective
To explore the application value of nursing intervention on diabetics based on the theory of protection motivation
.Methods
From March 2016 to January 2017,148 patients with type 2 diabetes admitted to our hospital were enrolled and randomly divided into observation group(n=74)and control group(n=74).In the control group,routine nursing intervention was used,while in the observation group,on the basis of the control group,nursing intervention based on the protection motivation theory was added.The value of the two nursing methods was compared and analyzed.
Results
After intervention,the knowledge scores，skill scores,blood glucose frequency,and glycated hemoglobin frequency in the two groups were significantly higher than those before intervention(P<0.05).The indexes mentioned above after intervention in the observation group were all superior to those in the control group(P<0.05).The fasting blood glucose in the observation group was(6.68±0.83)mmol/L,lower than that in the control group of(7.91±0.82)mmol/L,with a statistical difference(P<0.05).The postprandial blood glucose in the observation group was(7.19±0.40)mmol/L,also lower than that in the control group of(9.11±0.17)mmol/L,which was displayed a significant difference(P<0.05).The glycated hemoglobin in the observation group was lower than the control group with statistical significance(P<0.05).Conclusion For patients with diabetes,the application of nursing intervention based on protection motivation theory to clinical treatment can effectively improve the patients′biochemical indicators,set a good behavior habit,and enhance the ability to grasp blood glucose monitoring.Therefore,it has a remarkable clinical application value.
2018 Vol. 25 (15): 150-152转156 [
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156
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153
Research on influence of early intervention and holistic nursing on neonatal jaundice
OU Chu-wen
Objective
To explore the effect of early intervention and holistic nursing on neonatal jaundice.
Methods
The clinical data of 110 newborns who were hospitalized in the postpartum area of our hospital from April to October 2017 were studied.All the newborns were divided by the random number table method into the observation group（45 cases）and the control group（65 cases）.The control group was received routine basic nursing,while the observation group was received comprehensive holistic nursing and intervention on the basis of the control group.The daily bilirubin level,the first defecation time,the number of daily defecation and the incidence of pathological jaundice were recorded and compared between the two groups at post-operational 3 days.
Results
The daily bilirubin level of the observation group was significantly lower than that of the control group,the difference was statistically significant(P<0.05).The first defecation time of the observation group was significantly earlier than that of the control group,the difference was statistically significant(P<0.05).The number of daily defecation of the observation group was more than that of the control group,the difference was statistically significant(P<0.05).The incidence of pathological jaundice of the observation group was significantly lower than that of the control group,with statistically significant difference(P<0.05).
Conclusion
Early intervention and holistic nursing measures should be taken for neonates to reduce the daily neonatal bilirubin level and the incidence of neonatal pathological jaundice,which is of great significance and worthy of clinical promotion.
2018 Vol. 25 (15): 153-156 [
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125
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157
Analysis on applying clinical pathway to radiotherapy nursing for patients with metastatic brain tumor
CHENG Yu-ying;CHEN Xiao-ping
Objective
To study the clinical application of radiotherapy in patients with metastatic brain tumors.
Methods
From June to December 2017,78 patients with metastatic brain tumor who came to our hospital were randomly selected.All patients were divided into control group(n=39)and study group(n=39)according to random number table method.The control group was given conventional nursing care.The study group was given clinical pathology care.The total effective rate of clinical nursing,quality of life score,satisfaction and complication rate were compared between the two groups.
Results
The quality of life score,total effective rate of clinical nursing and satisfaction of study group were significantly higher than those of control group(P<0.05).The incidence of clinical nursing complication in study group was significantly lower than that of control group,the difference was statistically significant(P<0.05).
Conclusion
The clinical path nursing program for patients with metastatic brain tumors in radiotherapy and care can effectively reduce the treatment of patients with discomfort,to achieve the desired effect of clinical care，improve patient quality of life,clinical application of significant value.
2018 Vol. 25 (15): 157-159 [
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149
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160
Effect of comprehensive nursing intervention on the rehabilitation of children after urethral small fissure operation
CHU Lin;ZHAO Bing-ru;ZHANG Lin
Objective
To explore the best nursing method for children with urethral hypospadias after operation.
Methods
A total of 76 Children with hypospadias treated in our hospital were selected as subjects from October 2016 to September 2017.According to time of admission,they were divided into routine group (37 cases)and comprehensive group(39 cases).The routine group was adopted traditional nursing method,and comprehensive nursing intervention was carried out in the comprehensive group.Defecation,pain,complications and hospital stay were compared between the two groups.
Results
The defecation in the comprehensive group was better than that in the routine group (P＜0.05）,and the pain score in the comprehensive group was lower than that in the conventional group(P＜0.05）.The incidence of urinary fistula,urethral stricture and urethral asphyxia in the combined group was lower than that in the routine group(P＜0.05）.The duration of hospitalization in the comprehensive group was shorter than that in the conventional group,the differences were statistically significant(P＜0.05）.
Conclusion
Comprehensive nursing intervention can effectively improve the rehabilitation effect of children after urethral hypospadias,and the effect is remarkable.
2018 Vol. 25 (15): 160-162 [
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151
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Effect analysis of comprehensive nursing intervention on patients with severe bleeding after tonsillectomy
KUANG Ying-qiao
Objective
To study the effect of comprehensive nursing on patients with severe bleeding after tonsillectomy.
Methods
From January 2015 to October 2017,56 patients who underwent tonsillectomy in our hospital were selected as the research subjects.The causes of postoperative severe bleeding in all participants were analyzed.Comprehensive nursing intervention was provided and the clinical effect before and after intervention was observed.
Results
After the intervention,the patient′s pain score was lower than before with a significant difference(P<0.05).After the intervention,the patient′s satisfaction with service was higher than before and the postoperative re-bleeding rate was lower compared with intervention before,which were displayed statistical significance(P<0.05).Meanwhile,the quality of daily life of the patients after the intervention was higher than before with a statistical difference(P<0.05).
Conclusion
For patients with severe bleeding after tonsillectomy,application of comprehensive nursing intervention obtains satisfactory effects.It is feasible to reduce the rate of re-bleeding,relieve patients′pain,and improve the quality of daily life of patients to some extent.The value of clinical promotion is extremely high.
2018 Vol. 25 (15): 163-165 [
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136
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166
Application effect of high-quality nursing in laparoscopic cholecystectomy
WANG Yu-zhen
Objective
To study and analyze the clinical application effect of high-quality nursing in laparoscopic cholecystectomy.
Methods
A total of 90 patients undergoing laparoscopic cholecystectomy in our hospital from July 2017 to January 2018 were enrolled and randomly divided into control group and research group,45 cases in each group.In control group,the clinical routine care mode was used,while in research group,high-quality nursing on the basis of the control group was added.The clinical efficacy in the two groups was carefully observed.
Results
The scores of self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were significantly lower compared with those in the control group with statistical differences(P<0.05).The time to be off bed,first exhaust time,and hospital stay in the research group were all shorter than those in the control group with statistical significance (P<0.05).The nursing satisfaction in the research group was 97.73%,which was higher than that in the control group accounting for 81.82%with a statistical difference (P<0.05).The incidence of adverse reactions was lower in the research group than in the control group (P<0.05).
Conclusion
Application of high-quality nursing for patients undergoing laparoscopic cholecystectomy obtains a favorable clinical effect,which is worthy of promotion.
2018 Vol. 25 (15): 166-168 [
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149
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Analysis of the related factors of surgical incision infection
LI Yin
Objective
To analyze the relationship between surgical incision infection and related factors of operating care management in the operating room as a basis for clinical nursing in order to decrease the incidence of infection.
Methods
A total of 2025 general surgical patients admitted to our hospital from March 2016 to September 2017 were enrolled as research subjects.The clinical data of these patients were analyzed retrospectively to calculate the incidence of surgical incision infection and analyze the related factors.
Results
The univariate analysis showed that the relevant risk factors affecting surgical incision infection were operation time,type of surgery,whether it was a continuous operation,whether it was an invasive operation,whether antibiotics used prophylactically,and whether someone observing operation with statistical significance(P<0.05).Multivariate analysis showed that the independent risk factors leading to surgical incision infection were operative time＞2 hours,continuous operation,invasive operation,and preventive use of antibiotics(P<0.05,OR＞1).
Conclusion
There are many clinical factors that cause surgical incision infection in patients.Therefore,in the nursing management of the operating room,nursing measures should be drafted and regulated targeted on the specific factors in order to reduce the incidence of incision infection and ensure the health and safety of patients.
2018 Vol. 25 (15): 169-171 [
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140
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172
Application effect of high-quality nursing intervention on postpartum hemorrhage in puerperae with pregnancy-induced hypertension
DENG Jie-jun
Objective
To study the effect of high-quality nursing intervention on postpartum hemorrhage in puerperae with pregnancy-induced hypertension.
Methods
From May 2016 to May 2017,60 puerperae with postpartum hemorrhage admitted to our hospital were selected as research objects.By a random number table method,they were divided into research group (n=30)and control group (n=30).In the research group,high-quality nursing intervention was used,while in the control group,routine postpartum nursing intervention was adopted.The postpartum hemorrhage volume and maternal blood pressure changes between the two groups were compared
.Results
After high-quality nursing intervention,the blood loss 2 and 24 hour after delivery were(99.08±11.42)ml and (133.11±18.34)ml,lower than those in the control group of(154.22±13.85)ml and(244.20±19.07)ml,which were displayed statistical significances(P<0.05).The systolic blood pressure and diastolic blood pressure in the research group were(125.28±9.48)mmHg and(84.28±6.53)mmHg,both lower than those in the control group of(140.07±10.04)mmHg and(90.18±7.56)mmHg with statistical significance(P<0.05).The neonate birth weight and Apgar score were(3.50±0.43)kg and(9.80±0.92)points in the research group,superior to those in the control group of(2.43±0.20)kg and(8.01±0.40)points respectively.The above-mentioned two parameters were displayed significant differences between the two groups (P<0.05).
Conclusion
The application of highquality nursing intervention in the clinical nursing of puerperae with pregnancy-induced hypertension can effectively control the increase of blood pressure,reduce postpartum hemorrhage,and ensure the safety of maternal life.
2018 Vol. 25 (15): 172-174 [
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151
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175
Effect of system of nursing on quality of life the and living habits of patients with gastric ulcer
WEN Zhi-hui
Objective
To explore the effect of systematic nursing on the quality of life and habits of patients with gastric ulcer.
Methods
A total of 86 patients with gastric ulcer admitted to our hospital from June 2016 to January 2018 were divided into observation group(43 cases)and control group(43 cases)according random number table method.Patients in the control group were given routine nursing,while those in the observation group were given systematic nursing.SAS,SDS,QOL and Barthel scores were compared between the two groups.
Results
The scores of SAS and SDS in the observation group were(40.1±4.3)points and (41.3±3.9)points respectively after treatment,while those in the control group were(55.7±5.3)points and(53.7±5.1)points respectively after treatment.The scores of SAS and SDS in the observation group were significantly lower than those in the control group (P<0.05).There was no difference in QOL score and Barthel score between the two groups before treatment(P＞0.05).After treatment,the QOL score and Barthel score of the observation group were (91.7±6.5)points and (90.3±7.7)points respectively,while the QOL score and Barthel score of the control group were(71.3±5.9)points and(73.9±7.5)points respectively,the QOL score and Barthel score of the observation group were significantly higher than those of the control group (P<0.05).The satisfaction and total effective rate of the observation group were 95.35%and 97.67%respectively,and the satisfaction and total effective rate of the control group were 81.40%and 86.05%respectively,the satisfaction and total effective rate of the observation were higher than those of the control group,the differences were statiscally sigmficant(P<0.05).
Conclusion
Systematic nursing can effectively improve the anxiety and depression of gastric ulcer patients,improve the quality of life of patients,so as to cultivate healthy living habits of patients,has clinical significance.
2018 Vol. 25 (15): 175-177 [
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155
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Application of body language communication in pediatric nursing
LI Juan
Objective
To analyze and discuss the comprehensive effect and clinical value of applying body language communication in pediatric nursing.
Methods
A total of 126 children who were admitted to our hospital from March 2015 to April 2017 were selected as the study subjects.They were divided into two groups according to the accepted clinical care methods.The reference group (62 cases)was received routine nursing measures and the study group(64 patients)was received regular care and communicated using body language.The clinical effects of the two nursing methods were compared and analyzed.
Results
The degree of treatment in the study group was higher than the reference group,and the difference was statistically significant(P<0.05);the nursing quality score in the study group was higher than the reference group,the difference was statistically significant(P<0.05);the study group was satisfied with the nursing work,the degree of evaluation was higher than that in the reference group,and the difference was statistically significant(P<0.05).
Conclusions
It is more beneficial to improve the quality of nursing care and obtain the approval of the family members of children in strengthening the body language communication mode in children nursing work.
2018 Vol. 25 (15): 178-180 [
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149
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181
Impact of early acupoint massage combined with moxibustion in the lactation and prognosis after the cesarean section
SU Wen-biao
Objective
To analyze the impact of moxibustion combined with early acupoint massage in the lactation after the cesarean section.
Methods
After the cesarean section,200 puerpera with hypogalactia treated in our hospital from January to December 2017 were selected.The subjects were assigned to two groups according to the odd or even hospital bed number,100 cases in each group.The control group was received the conventional nursing care;on the basis of the former,the observation group was received the moxibustion combined with early acupoint massage.The lactation yield,initial lactation time,breast pain and swelling conditions,prolactin levels as well as the ratio with sufficient lactation yield after 1 and 3 d of intervention were probed.
Results
The pain and swelling scores and lactation time were remarkably reduced in the observation group(P＜0.05）;after 1 and 3 d of intervention,the ratio with sufficient lactation yield,lactation yield and prolactin levels were remarkably increased in the observation group (P＜0.05）
.Conclusion
After the cesarean section,the moxibustion combined with early acupoint massage can shorten the initial lactation time,increase the lactation yield and prolactin levels,and relieve the breast pain and swelling conditions.
2018 Vol. 25 (15): 181-184 [
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160
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Application of effect of evidence-based nursing mode in liver and spleen rupture surgery
LI Cai-xia;LIU Hong-kai
Objective
To analyze the specific effect and practical value of evidence-based nursing mode after liver and spleen rupture surgery.
Methods
Altogether 78 patients who underwent liver and spleen rupture surgery in our hospital from December 2014 to December 2017 were selected and divided into control group and observation group according to the order of admission,39 cases in each group.The control group was treated with conventional nursing mode,while the observation group was treated with evidence-based nursing mode.The activities of daily life (ADL)quality of life score,visual analogue scale(VAS)pain score,length of stay,complication rate,nursing satisfaction and total effective rate were compared between the two groups.
Results
The post-nursing ADL quality of life score and VAS pain score of the observation group and the control group were higher than those before the nursing,with statistically significant difference(P<0.05).There was no statistically significant difference between the two groups in pre-nursing ADL quality of life score and VAS pain score(P＞0.05).The post-nursing ADL quality of life score,VAS pain score and length of stay of the observation group were significantly higher than those of control group,with statistically significant difference(P<0.05).The incidence of complications of the observation group was 7.69%,lower than that of the control group (23.08%),with statistically significant difference (P<0.05).The nursing satisfaction of the observation group was 94.88%,higher than that of the control group(79.48%),with statistically significant difference(P<0.05).The total effective rate of the observation group was 97.44%,higher than that of the control group(82.06%),with statistically significant difference(P<0.05).
Conclusion
Application of evidence-based nursing model for patients with liver and spleen rupture can effectively shorten the patients′hospitalization time,improve the quality of life and reduce the pain perception and complication rate,with generally good patients′reflection and obvious overall nursing effect,which can be popularized in the major hospitals.
2018 Vol. 25 (15): 185-188 [
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141
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189
The value of high quality nursing in the treatment of hypertension in the elderly
ZOU li
Objective
To study the effect of quality nursing on elderly hypertensive patients.
Methods
The data of 50 elderly hypertensive patients admitted to our hospital from September 2016 to December 2017 were analyzed.According to the admission number,they were divided into control group and study group,25 patients in each group.The control group was used for routine care.The research group was used quality care based on routine care.The quality of life,care satisfaction，blood pressure,and care compliance were campared between two groups.
Results
The study group had higher satisfaction with nursing than that in the control group.The quality of life score was higher than that of the control group.The blood pressure was lower than that of the control group.The medication compliance rate and life compliance rate were higher than those of the control group.The differences were statistically significant(P<0.05).Conclusion Inpatients with hypertension in the elderly are on the basis of routine nursing care.The quality of care will improve the quality of life of patients.It is worthy of clinical application.
2018 Vol. 25 (15): 189-191 [
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133
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192
Analysis of the effect of WeChat platform health education on patients with leukemia PICC catheterization
CHEN Jun-e;YE Dan-qing;WU Lin
objective
To explore the effect of health education on PICC patients with leukemia on WeChat platform.
Methods
From January 2015 to March 2017,70 patients with leukemia PICC catheterization in our hospital were selected as the objects of this study.Patients were divided into control group (routine PICC catheter nursing)and observation group(routine catheter nursing)according to different nursing methods,35 cases in each group.The incidence of adverse events and catheter indwelling time after nursing in the two groups were observed and compared
.Results
The incidence rate of adverse events such as puncture point infection,phlebitis,catheter related infection,accidental tube removal,catheter blockage and adverse events in the observation group were 17.14%,lower than those in the control group(48.57%),with statistical difference(χ
2
=7.835,P<0.05).The nursing satisfaction of the observation group was 97.14%,higher than that of the control group(77.14%),with statistical difference(χ
2
=3.584,P<0.05).The catheter indwelling time in the observation group was(139.5±16.2)days which was longer than that in the control group([115.2±14.3]days),and there was significant difference between the two groups(t=6.652,P<0.05).
Conclusion
WeChat platform health education has good nursing effect for patients with leukemia PICC catheter,which can reduce adverse events,prolong catheter retention time and improve patient satisfaction,and is worthy of clinical application.
2018 Vol. 25 (15): 192-194 [
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151
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Application value of comprehensive nursing care in premature infants with frequent
LIU Li-hua;HU Yan-ling;CHEN Xue-mei;WU Jie-li
Objective
To summarize the value of comprehensive nursing in the nursing of premature infants with frequent apnea.
Methods
From April 2014 to July 2017,the clinical data of 60 cases in our hospital admitted to the frequent episodes of apnea were retrospectively analyzed,both groups underwent unified comprehensive treatment,according to the different points of care programs,all patients were divided into the two groups,the control group of 30 patients were used routine nursing,on the basis of the control group,the comprehensive nursing intervention were used in experimental group of 30 patients.The two groups of nursing intervention effect were compared.
Results
After intervention,the total effective rate of experimental group was significantly higher than that of control group (93.33%vs.70.00%),the difference was statistically significant(P<0.05).The frequency,duration,the indicators of additional stimulation rate,aminophylline use time,oxygen inhalation time and continuous positive pressure ventilation duration,the data of the experimental group were significantly lower than those of the control group (P<0.05).After intervention,the transcutaneous blood,oxygen saturation,heart rate and other indicators of the experimental group were significantly higher than the control group,the differences were also statistically significant(P<0.05).
Conclusion
The comprehensive nursing intervention applied to frequent premature infants with prolonged sleep apnea can get better results,which can help reduce the frequency of apnea,reduce the degree of attack,improve clinical certificates in children,to further improve the quality of life of children with clinical promotion value.
2018 Vol. 25 (15): 195-197 [
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132
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