低位恶性梗阻性黄疸行胰十二指肠切除术术前减黄的临床观察

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Abstract Objective To observe the effect and incidence of complications of preoperative biliary drainage before pancreatoduodenectomy for low malignant obstructive jaundice.Methods The data of 78 patients with lower malignant obstructive jaundice who were treated from January to December 2017 in our hospital were collected.All the patients were treated with pancreatoduodenectomy and divided into two groups preoperatively according to whether preoperative biliary drainage was conducted or not.Among them,36 patients who were given preoperative biliary drainage were taken as biliary drainage group;while,42 case who were not given preoperative biliary drainage were taken as control group.The total bilirubin（TB）before and after preoperative biliary drainage of biliary drainage group was observed.The perioperative indicators，postoperative morbidity and mortality were compared between the two groups.Results The TB level of biliary drainage group before radical resection was（209.62±22.96）μmol/L，which was significantly lower than that before biliary drainage（[311.07±39.76]μmol/L）and that of the control group（[297.83±42.69]μmol/L）before radical resection，both with statistically significant difference（P<0.05）.The preoperative treatment duration and total treatment time of biliary drainage group were longer than those of control groups;and the allogenic erythrocyte infusion volume of biliary drainage group was less than that of control group，with statistically significant difference（P<0.05）.There was no statistically significant difference in the mean operation time，mean blood transfusion volume and postoperative hospital stay between the two groups（P＞0.05）.The incidence of complications and mortality rate of biliary drainage group were 61.11%and 0.00%versus control group′s 66.67%and 2.38%，respectively，without statistically significant difference（P＞0.05）.Conclusion Application of preoperative biliary drainage before pancreatoduodenectomy for low malignant obstructive jaundice can reduce the level of total bilirubin，but has no significant effect on the prognosis of patients.

Key words： Low malignant obstructive jaundice')" href="#">Low malignant obstructive jaundice Pancreatoduodenectomy Biliary drainage Efficacy Complications

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	XU Ma-chuan
	XIE Wei
	FENG Shi-jian
	HE Guo-shai
	CHEN Wan-mei

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XU Ma-chuan,XIE Wei,FENG Shi-jian, et al. Clinical observation of preoperative biliary drainage before pancreatoduodenectomy for low malignant obstructive jaundice[J]. 中国当代医药, 2018, 25(15): 19-21转25.

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