复方多粘菌素B软膏联合阿达帕林凝胶治疗寻常型痤疮的效果和安全性分析

Abstract
Figure/Table
References (19)
Related Citation (2)

Download: PDF (0 KB) HTML (34 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study and analyze the clinical effects and safety of Compound Polymyxin B Ointment combined with Adapalene Gel in treatment of acne vulgaris.Methods A total of 128 cases of patients with acne vulgaris who treated in our hospital from January 2016 to August 2017 were selected as subjects,and were divided into the observation group and the control group according to the random number grouping method,with 64 cases in each group.The patients in the control group were treated with only Compound Polymyxin B Ointment,while the patients in the observation group were treated with Compound Polymyxin B Ointment combined with Adapalene Gel.The effects,the occurrence of adverse reactions and the skin lesions counts after treatment of patients between the two groups were observed.Results The total effective rate of the patients in the observation group was 98.44%,which was significantly higher than that in the control group of 87.50%,the difference was statistically significant(P<0.05).The total incidence of adverse reaction in the observation group was 9.38%,which was significantly lower than that in the control group of 21.88%,the difference was statistically significant(P<0.05).The skin lesions(papule,comedo,pimple)counts of the patients in the observation group were less than those of the control group,and the differences were statistically significant(P<0.05).Conclusion The effect of Compound Polymyxin B Ointment combined with Adapalene Gel in treatment of acne vulgaris are significant,which greatly reduce the patients′skin lesion counts,promotes the recovery of the patient,and it have high safety,thus it is worth promoting and using in clinical.

Key words： Compound Polymyxin B Ointment Adapalene Gel Acne vulgaris

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LIU Yu-qian
	LAI Yong-hui
	WEN Li-zhang
	YANG Fan
	PAN Peng
	MO Yan-shi
	LUO Bin

Cite this article:

LIU Yu-qian,LAI Yong-hui,WEN Li-zhang, et al. Analysis of clinical effect and safety of Compound Polymyxin B Ointment combined with Adapalene Gel in treatment of acne vulgaris[J]. 中国当代医药, 2018, 25(15): 88-90.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I15/88

[1]	马锡俊，李彦，王西京.红蓝光联合0.1%阿达帕林凝胶治疗寻常痤疮患者的疗效及安全性分析[J].中国医疗美容，2017，7（3）：67-69.
[2]	陈海亭，赵一彧，徐甜甜，等.黄地养阴颗粒联合夫西地酸乳膏及阿达帕林凝胶治疗寻常型痤疮的疗效观察[J].中国中西医结合皮肤性病学杂志，2016，15（3）：178-179.
[3]	杨俊文，黄紫静，邓列华.不同浓度的阿达帕林凝胶治疗寻常型痤疮临床近期疗效观察[J].心理医生，2017，23（6）：15-16.
[4]	王是，刘晓明.中西医结合治疗寻常型痤疮的临床观察[J].武汉大学学报（医学版），2016，37（6）：995-997.
[5]	曾世华，袁霞，刘兰.果酸联合阿达帕林凝胶治疗毛周角化病疗效评价[J].中国麻风皮肤病杂志，2016，32（10）：620-622.
[6]	徐杨斌，邓丹.阿达帕林凝胶联合过氧苯甲酰凝胶外用治疗中度寻常痤疮效果观察[J].中国乡村医药，2016，23（10）：33-34.
[7]	康金陵.果酸焕肤术治疗寻常性痤疮疗效观察[J].中国美容医学杂志，2016，25（5）：79-81.
[8]	李洁，刘洪坤，侯丽，等.寻常性痤疮证候分布规律现代文献分析[J].山东中医杂志，2016，35（6）：496-497.
[9]	姜鹏爽，石云.夫西地酸乳膏联合多磺酸黏多糖乳膏治疗寻常痤疮疗效观察[J].中国中西医结合皮肤性病学杂志，2017，16（4）：318-320.
[10]	王山而，杨雪萍.阿达帕林凝胶联合多西环素治疗痤疮的效果分析[J].现代实用医学，2017，29（5）：665-666.
[11]	马小琴.消痤方联合西药治疗痤疮的疗效观察[J].陕西中医，2016，37（5）：604-605.
[12]	伍筱铭，王思农，肖佼，等.三黄凝胶治疗寻常型痤疮25例[J].中医外治杂志，2016，25（2）：16-17.
[13]	唐燕，吴莉红，黎茵，等.复方参芷酊联合阿达帕林凝胶治疗痤疮疗效观察[J].深圳中西医结合杂志，2016，26（11）：56-57.
[14]	刘艳，王羿婷，毕志刚.阿达帕林凝胶联合多西环素胶囊治疗痤疮的临床研究[J].现代中西医结合杂志，2016，25（9）：966-968.
[15]	卢富琼，余珍，杨帆.果酸换肤联合阿达帕林凝胶外用治疗轻中度痤疮的效果观察[J].中国当代医药，2016，23（35）：37-39.
[16]	胡艳阁.中药外洗方联合阿达帕林凝胶治疗面部扁平疣临床观察[J].实用中医药杂志，2017，33（4）：431-432.
[17]	朱珂，齐庆，李东海，等.枇杷清肺饮加减联合红蓝光照射治疗中、重度寻常性痤疮疗效观察及安全性评价[J].中国美容医学杂志，2017，26（2）：114-117.
[18]	罗易，林凤云.红蓝光联合莫匹罗星治疗寻常型痤疮的疗效观察[J].保健医学研究与实践，2017，14（4）：66-68.
[19]	赵艳，胡燕.果酸联合丹参酮治疗寻常性痤疮疗效观察[J].内蒙古中医药，2017，36（6）：62.