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Quick Search     Adv Search 2018 Vol. 25, No. 8 Published: 2018-03-18   9 Correlation analysis of aromatic hydrocarbon receptor and recurrent spontaneous abortion ZHANG Xiao-ting;ZHANG Yue-lian; HUANG Ya-ling Objective To analyze the correlation between aromatic hydrocarbon receptor (AHR)and human chorionic gonadotropin(HCG),estradiol(E2),progesterone(P),estrogen receptor(ER),and progesterone receptor(PR),and to explore the relationship between AHR and recurrent spontaneous abortion (RSA).Methods From December 2016 to March 2017,30 RSA patients treated in the Department of Obstetrics and Gynecology,Shanxi Academy of Medical Sciences were selected as the research group.30 patients with abortion requiring in normal early pregnancy were categorized into the control group.The peripheral blood,villi and decidua tissues were collected.The levels of serum AHR,HCG,E2,P,ER and PR from villi and decidua tissues were detected and statistically analyzed.Results The AHR levels in the villi and decidua tissues in the research group were significantly higher than those in the normal control group(P＜0.05).There was no significant difference in the serum AHR levels between the two groups(P＞0.05).The level of serum HCG,P and E2in the research group were significantly lower compared with those in the normal control group (P＜0.05).The levels of ER and PR in villus and decidua tissues in the research group were significantly lower,in comparison with those in the control group (P＜0.05).There was no correlation between the serum AHR and HCG,P and E2.The AHR in the villi and decidua tissues was not correlated with ER or PR in the corresponding areas.Conclusion The elevated AHR in human may lead to RSA,especially the increase of AHR in the local villi and decidua tissues.The decrease of ER and PR expression is also the cause of RSA.However,the increase of AHR is not associated with ER or PR.Increase of AHR will may directly influence on pregnancy outcome or by other pathways except ER and PR.Meanwhile,ER and PR will not affect the rise of AHR,either. 2018 Vol. 25 (8): 9-12 [Abstract] ( 185 ) HTML (37 KB)  PDF  (0 KB)  ( 28 ) 13 Cardioprotection effect on myocardial ischemia reperfusion injury of LCarnitine in patients undergoing percutaneous coronary intervention CHEN Han-xiang;LI Qi;ZHOU Wei;PENG Chao-hua Objective To investigate cardioprotection effect on myocardial ischemia reperfusion injury of L-Carnitine(L-C)in patients with coronary heart disease(CHD)undergoing percutaneous coronary intervention(PCI).Methods Sixty patients with CHD undergoing PCI from April 2014 to December 2016 in our hospital were selected and divided into the treatment group and the control group through a random number table method,30 cases in each group.The control group was treated with PCI and oral Aspirin(100 mg,1 time/d),Clopidogrel(75 mg,1 time/d),Atorvastatin Calcium Tablet(20 mg,every night),Metoprolol Zyban(23.75-47.50 mg,1 time/d),Single Isosorbide Nitrate Ester Zyban(40 mg,2 times/d).The treatment group was injected with the L-Carnitine 2.0 g intravenous drip before operation on the basis of the control group and continued once a day for 7 days after surgery.The concentration of CK-MB,cTnI,CRP,BNP,FFA and LVEF before and after PCI were compared between the two groups.Results LVEF in the two groups after operation were higher than those before PCI,with significant diference(P＜0.05).The indexes of CK-MB,cTnI,CRP,BNP and FFA after PCI in the treatment group were lower than those in the control group,and LVEF was higher than that of the control group,with significant diference(P＜0.05).Conclusion L-Carnitine has cardioprotection effect on myocardial ischemia reperfusion injury in patients with CHD undergoing PCI.It can improve myocardial energy metabolism and cardiac function. 2018 Vol. 25 (8): 13-16转20 [Abstract] ( 173 ) HTML (35 KB)  PDF  (0 KB)  ( 26 ) 17 Clinical effect of laparoscopic sacral colpopexy in the treatment of pelvic organ prolapse GAO Hang;HOU Jia-yu;DENG Yan-jie Objective To investigate the efficacy and satisfaction of laparoscopic sacral colpopexy in patients with pelvic organ prolapse.Methods A total of 47 patients with severe uterine prolapse(stage POP-QⅢ-Ⅳ)confirmed by POP-Q staging from January 2014 to September 2016 in Dalian Maternal and Child Health Care Hospital and underwent laparoscopic sacral colpopexy were selected,POP-Q staging,PFD symptom questionnaire (PFDI-20)and influence questionnaire (PFIQ-7)were used to evaluate the symptoms and quality of life of the pelvic floor at 6 months after the operation.Results All patients were followed up within six months after surgery.Only 1 case had recurrent vaginal anterior wall prolapse(POP-QⅡ),the recurrence rate was 2.12%(1/47);and 3 cases were newly diagnosed with urinary incontinence,the incidence rate was 8.57%(3/35);2 patients were newly frequency of frequent urination,the incidence rate was 6.25% (2/32).1 case was troubled by dysuria,the rate was 2.7% (1/37),and the incidence rate for constipation was 22.2% (1/45).There were 1 cases of new chronic pelvic pain,the incidence of which was 2.13% (1/47).In the POP-Q staging,the median of anatomical locations of Aa,Ba,C,Ap and Bp were restored from 1.0,3.0,2.0,－3.0,－2.0 cm before operation to －3.0,－3.0,－6.0,－3.0 and －3.0 cm after operation,which were significantly lower than that before operation(P=0.00).The length of the perineal body(Pb)was significantly increased,compared with before operation(P=0.00),genital hiatus length shortened significantly（P=0.00),but there was no significant change in the total length of the vagina(P=0.16).The median scores of questionnaire of PFIQ-7 and PFDI-20 were reduced from 70.38 points and 71.43 points preoperatively to 0.00 points and 9.52 points postoperatively,the difference was statistically significant(P=0.00).The total score of PFIQ-7 was higher than that of PFDI-20 after operation,the scores of POPDI-6,POPIQ-7,UDI-6 and UIQ-7 after operation of the two groups were significantly lower than those before operation(P=0.00),there was no significant difference in the CARDI-8 and CARIQ-7 scores between before and after operation.Conclusion Laparoscopic sacral colpopexy is an effective method for the treatment of pelvic prolapse,the surgical trauma and complications are less,it can keep the original length of the vagina and prevent the recurrence of vaginal fornix prolapse. 2018 Vol. 25 (8): 17-20 [Abstract] ( 208 ) HTML (35 KB)  PDF  (0 KB)  ( 32 ) 21 Analysis on mechanism of effects of Amiloride on rats with pulmonary ischemia reperfusion injury LIU Wei-cun Objective To explore the mechanism of effects of Amiloride on rats with pulmonary ischemia reperfusion injury.MethodsSeventy-two experimental male rats were selected and randomly divided into the IR group (the ischemia reperfusion group),the sham operation group(group C)and the Amiloride group(group A),24 rats in each group.After 45 min ischemia,60 min reperfusion and 120 min,rats in each group were anesthetized and killed,then plasma and right lung tissues were taken and detected.Results At 60 and 120 min reperfusion,malondialdehyde(MDA),apoptosis index(AI)in the IR group were significantly higher than those in the sham operation group.The Amiloride group was given drugs,MDA and AI were significantly lower,compared with the IR group(P＜0.05).Compared with the sham operation group,the lung wet/dry weight ratio(W/D)and myeloperoxidase(MPO)activity in the IR group at each time point were significantly increased(P＜0.05),while Amiloride after administration,the W/D in lung tissue and MPO activity decreased significantly.ConclusionAmiloride on lung ischemia reperfusion injury has a strong protective effect,this may be by reducing calcium ion,so as to remove the body of excess oxygen free radicals and inhibition of neutrophil infiltration and reduce cell apoptosis of purpose. 2018 Vol. 25 (8): 21-23 [Abstract] ( 153 ) HTML (32 KB)  PDF  (0 KB)  ( 34 ) 24 Effect of Budesonide combined with Salbutamol Aerosol Inhalation in the treatment of acute exacerbation of chronic obstructive pulmonary disease LI Yan Objective To investigate the clinical effect of Budesonide combined with Salbutamol Aerosol Inhalation in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods A total of 270 AECOPD patients collected in our hospital from January 2016 to March 2017 were selected and randomly divided into the Budesonide monotherapy group,the Salbutamol monotherapy group and the combination group,which were called group A,B and C.The three groups were all given basic treatment.On the basis of basic treatment,patients in group A were given Budesonide suspension,group B was given Salbutamol Sulfate,group C was given Budesonide suspension and Salbutamol Sulfate.The clinical efficacy,6 min walking distance (6 MWD),dyspnea score and lung function were observed in the three groups,as well as the occurrence of adverse reactions.Results The total effective rate of group C was 96.67%,which was significantly higher than that of group A and B (P＜0.01).There was no significant difference in the total efficiency of group A and B (P＞0.05).Meanwhile,after treatment,the 6MWD scores,dyspnea scores and pulmonary function indexes of the three groups of A,B and C improved significantly(P＜0.01),and the improvement rate of group C was significantly higher than that of group A and B (P＜0.05),but there was no significant difference between group A and B(P＞0.05).There was no significant difference in the incidence of adverse reactions between the three groups(P＞0.05).Conclusion In the treatment of AECOPD,Budesonide combined with Salbutamol Aerosol Inhalation is better than that single drug inhalation.It has better clinical effect,which can significantly improve the clinical symptoms and lung function,and the incidence of adverse reactions is low.It is worth promoting widely in clinic. 2018 Vol. 25 (8): 24-26转30 [Abstract] ( 231 ) HTML (31 KB)  PDF  (0 KB)  ( 32 ) 27 Progress in the study of new type of bronchopulmonary dysplasia in premature infants ZHU Yi-xin;ZHANG Hua Neonatal bronchopulmonary dysplasia is a chronic lung disease.With the development of medical technology,premature bronchopulmonary dysplasia has changed from classical to new.At present,the incidence of bronchopulmonary dysplasia is increasing year by year,and the smaller the gestational age,the higher the incidence of bronchopulmonary dysplasia.In this paper,we summarized the etiology,basic characteristics,diagnosis and treatment of new BPD.Focus on the pathological characteristics of the new BPD,performed animal experiments and clinical trial,which may become a hot research topic for premature infants with bronchopulmonary dysplasia. 2018 Vol. 25 (8): 27-30 [Abstract] ( 167 ) HTML (34 KB)  PDF  (0 KB)  ( 36 ) 31 Progress in surgical treatment of pterygium PENG Ting;ZHOU Qi-zhi Pterygium is one of the most common ocular surface diseases,but the pathogenesis is unclear,surgical treatment is still the main treatment at present,Pterygium often recurrence after pterygium resection,to reduce the recurrence rate,there is a wide range of research both at China and abroad,and has not reached a consensus.This article reviews and summarizes the latest advances in the study of pterygium surgery at home and abroad,and in order to help clinical treatment. 2018 Vol. 25 (8): 31-33 [Abstract] ( 171 ) HTML (31 KB)  PDF  (0 KB)  ( 33 ) 34 MELD score predicting short-term clinical prognosis in patients with acute mushroom poisoning TIAN Xiao-li;WU Song-lin;WU Gang Objective To investigate the clinical value of model for end-stage liver disease (MELD)score predicting short-term prognosis in patients with acute mushroom poisoning which leads to liver function damage.Methods From July 2014 to September 2017,20 cases with acute mushroom poisoning admitted into infection and digestive department in our hospital were enrolled the study.According to whether there was survival or death at discharge,they were divided into the survival group and death group.The differences of clinical manifestation and experimental examinations were compared.Results There were 12 patients were survival and 8 patients dead due to deterioration of the condition.There was no great difference in alanine transaminase (ALT),aspartate aminotransferase (AST),total bilirubin(TBil),albumin(Alb),creatinine(SCr),and white blood cell(WBC).MELD and prothrombin time activity(PTA)were displayed statistical differences(P=0.001,P=0.047).The receiver operating characteristic(ROC)curve was drawn with MELD to determine the short-term prognosis,and the area under the curve was 0.927.MELD＜14.57 points was selected as a predictor of mushroom poisoning threshold of patients with good prognosis,and the sensitivity and specificity was 100%and 75%respectively.Conclusion MELD score can effectively predict the short-term prognosis in patients with liver function damage caused by acute mushroom poisoning. 2018 Vol. 25 (8): 34-36转42 [Abstract] ( 182 ) HTML (30 KB)  PDF  (0 KB)  ( 36 ) 37 Study of life quality improvement of sleep breathing cloud platform in CPAP treatment for patients with obstructive sleep apnea-hypopnea syndrome LU Yan-shan Objective To evaluate the influence of sleep breathing cloud platform on the quality of life (QOL)in patients with obstructive sleep apnea-hypopnea syndrome(OSAHS)in continuous positive airway pressure(CPAP)treatment.Methods From November 2015 to October 2016,100 patients with OSAHS treated in our hospital were enrolled and they were randomly divided into treatment group and control group.In the treatment group,sleep breathing cloud platform was used to manage the CPAP treatment.In the control group,CPAP treatment was managed by patients.The routine health guidance was provided by medical staff in both groups.QOL of patients after nursing between the two groups was compared.Results The compliance rates of using ventilator in the treatment group after 3 months and 6 months treatment were higher than those of the control group(P＜0.05).Before treatment,there was no significant difference of ESS score and SF-36 score was displayed between the two groups(P＞0.05).ESS score in the treatment group was slightly lower than those of the control group after 3 months and 6 months treatment(P＞0.05),and SF-36 score was higher than that of the control group (P＜0.05).Conclusion Application of sleep breathing cloud platform in the treatment of CPAP in patients with OSAHS can improve the compliance of the ventilator in patients and be beneficial to early recovery of the patients. 2018 Vol. 25 (8): 37-39 [Abstract] ( 169 ) HTML (29 KB)  PDF  (0 KB)  ( 31 ) 40 Clinical observation of subcutaneous injection of Bortezomib treating multiple myeloma LI Rong Objective To explore the clinical effect of subcutaneous injection Bortezomib treating multiple myeloma.Methods Clinical data of 46 patients with multiple myeloma treated in Department of internal medicine of hematology of our hospital from March 2012 to June 2017 were analyzed,and patients were divided into the two group according to the different treatment method.The control group(intravenous injection of Bortezomib,n=23)and observation group(subcutaneous injection of Bortezomib,n=23).The clinical curative effect,the incidence of adverse reactions of patients in the two group were observed.Results The total remission rate of observation group(78.3%)was higher than than that of the control group (56.5%),the incidence of adverse reactions was of observation group (8.7%)was lower than that of the control group (26.1%)(P＜0.05).Conclusion The total remission rate of clinical treatment of subcutaneous injection of Bortezomib treating multiple myeloma is high,and the incidence of adverse reaction is fewer.It is worthy of clinical promotion and application.The multiple myeloma patients by bortezomib hypodermic injection，clinical treatment total remission rate is high，adverse reactions rate is little，it is worth to be used. 2018 Vol. 25 (8): 40-42 [Abstract] ( 186 ) HTML (25 KB)  PDF  (0 KB)  ( 28 ) 43 Clinical significance of serum RBP,four items of coagulation and platelet index detection in the diagnosis of severe liver disease TAO Jing;XIE Tian-gang Objective To explore the clinical significance of serum RBP,four items of coagulation and platelet index detection in the diagnosis of severe liver disease.Methods Ninety-two patients with liver diseases admitted into our hospital from January 2015 to January 2017 were divided into the study group 1 and 2 according to the degree of illness,and there were 46 cases in each group.Among them,the study group 1 was patients with common liver diseases,and study group 2 was patients with severe liver diseases.46 cases of health examination in our hospital from January 2015 to January 2017 were selected as the control group.The serum RBP,four items of coagulation and platelet indexes were detected in three groups,and the results were analyzed.Results RBP level in the study group 1 and 2 were lower than those of the control group(P＜0.05).The Fib level in the study group 1 and 2 were lower than those in the control group,and PT,APTT,TT were all longer than those in the control group (P＜0.05).In the study group 1 and 2,PLT was lower than that of the control group,and MPV and PDW were higher than those in the control group (P＜0.05).Conclusion Serum RBP,four items of coagulation and platelet index detection are of great significance in the diagnosis of severe liver disease. 2018 Vol. 25 (8): 43-45 [Abstract] ( 169 ) HTML (27 KB)  PDF  (0 KB)  ( 27 ) 46 The curative effect and security analyzing of elderly late stage gastric cancer by Capecitabine combined with Thymic peptide LI Xu-dan;CHEN Hai-long Objective To approach curative effect and security analyzing of elderly late stage gastric cancer by Capecitabine combined with Thymic Peptide.Methods Sixty-four elderly patients with advanced gastric cancer admitted to our hospital from February 2014 to February 2016 were divided into treatment group A (Capecitabine treatment group)and treatment group B (Capecitabine combined with Thymic Deptide treatment group),with 32 cases in each group.The short-term efficacy,long-term efficacy and adverse reactions were compared between the two groups.Results The total remission rate of elderly patients with advanced gastric cancer in group B was higher than that in group A,while the progression time and survival time of elderly patients with advanced gastric cancer in group B were shorter than those in group A(P＜0.05),there was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The elderly late stage gastric cancer patients by Capecitabine combined with Thymic Peptide treatment，short-term curative effect and long-term curative effect are good，security is high，it is worth to be used. 2018 Vol. 25 (8): 46-48 [Abstract] ( 217 ) HTML (28 KB)  PDF  (0 KB)  ( 37 ) 49 Clinical observation of precise liver resection in patients with hepatocellular carcinoma JIANG Xu;YIN Qi;LI Zhe-Hao Objective To study the clinical effect of precise liver resection in patients with hepatocellular carcinoma.Methods A total of 64 patients with hepatocellular carcinoma diagnosed and treated in our hospital from September 2015 to July 2017 were divided into study group and conventional group according to different surgical methods,32 cases in each group.Patients in the study group underwent precise segmental hepatectomy,while patients in the conventional group underwent traditional hepatectomy.The operation-related indicators,postoperative liver function indicators and postoperative complications were compared between the two groups.Results In blood transfusion volume between the two groups，the difference was no significant difference(P＞0.05).The bleeding volume,operation time and postoperative hospital stay in the study group were significantly lower than those in the conventional group，the difference was statistically significant(P＜0.05).The incidence of postoperative complications in the study group was significantly lower than that in the conventional group，The difference was statistically significant(P＜0.05).After operation,ALT，TBil，ALB and other liver function indexes in the study group were significantly better than those in the conventional group，the difference was statistically significant(P＜0.05).Conclusion The precise liver resection has an obvious effect in patients with hepatocellular carcinoma,can reduce the intraoperative blood loss,shorten the hospitalization time,decrease the incidence rate of postoperative complications and improve the hepatic function. 2018 Vol. 25 (8): 49-51 [Abstract] ( 168 ) HTML (29 KB)  PDF  (0 KB)  ( 29 ) 52 Clinical effect of thoracoscopic lung cancer surgery in the treatment of elderly patients with non-small cell lung cancer ZHANG Ye;LI Chun-ling;HU Jian-ming;CHEN Jian;SUN Huang-tao;ZHOU Xin Objective To investigate and analyze the clinical effect of thoracoscopic lung cancer surgery in the treatment of elderly non-small cell lung cancer.Methods A total of 52 elderly patients with non-small cell lung cancer treated in our hospital from February 2016 to May 2017 were divided into control group and observation group by random number method.The control group was treated by traditional thoracotomy,while the observation group was treated by thoracoscopic radical lung cancer surgery.The changes of operation indexes,complication rate and biochemical indexes were compared between the two groups.Results The operation time of the observation group was longer than that of the control group,and the indwelling time and hospitalization time of the drainage tube were shorter than those of the control group (P＜0.05).The amount of bleeding during operation,the total amount of thoracic drainage and the amount of postoperative painkillers in the observation group were less than those in the control group (P＜0.05).There was no significant difference in the number of lymph node dissection between the two groups(P＞0.05).There was no significant difference between the two groups(P＞0.05).The incidence of incision infection and arrhythmia in the observation group were lower than those in the control group，the differences were statistically significant(P＜0.05).There was no significant difference between the two groups(P＞0.05).WBC,CRP and ALB in the observation group were significantly better than those in the control group,the difference was statistically significant(P＜0.05).Conclusion The clinical effect of thoracoscopic lung cancer surgery in the treatment of elderly non-small cell lung cancer is exact.It can effectively speed up postoperative recovery,reduce the incidence of complications and improve various biochemical indexes,and it has a positive clinical significance. 2018 Vol. 25 (8): 52-54 [Abstract] ( 200 ) HTML (31 KB)  PDF  (0 KB)  ( 34 ) 55 Effect of transcatheter arterial chemoembolization combined with Sorafenib in the treatment of primary liver cancer WEI Li-li;LONG De;ZHONG Zhuo Objective To investigate the effect of transcatheter arterial chemoembolization (TACE)combined with Sorafenib in the treatment of primary liver cancer.Methods From January 2014 to October 2017,60 patients with primary large hepatocellular carcinoma were selected as the research objects,and divided into study group and control group according to different treatment methods,30 cases in each group.Patients in the control group were treated with TACE alone,while patients in the study group were treated with Sorafenib on the basis of TACE.The therapeutic effect,liver function index and incidence of adverse reactions were compared between the two groups.Results The total clinical effective rate in the study group was significantly higher than that in the control group (P＜0.05).There was no significant difference between the two groups in ALB,ALT and TBil before operation (P＞0.05).After treatment,ALT and TBil in the study group were significantly better than those in the control group (P＜0.05).The incidence of adverse reactions in the study group was significantly lower than that in the control group(P＜0.05).Conclusion Compared with single treatment,combination of application of Sorafenib on the basis of TACE treatment in patients with primary liver cancer achieves more significant treatment effect,can effectively improve patients′liver function index with higher drug safety and no obvious side effects,which has high clinical application value. 2018 Vol. 25 (8): 55-57 [Abstract] ( 183 ) HTML (28 KB)  PDF  (0 KB)  ( 36 ) 58 Clinical effect of one-stage resection in the treatment of acute intestinal obstruction caused by colon cancer QIN Yong-jian Objective To explore the clinical effect of one-stage resection in the treatment of acute intestinal obstruction caused by colon cancer.Methods From January 2011 to January 2015,66 patients with acute intestinal obstruction caused by colon cancer were selected and randomly divided into observation group and control group,33 cases in each group.The therapeutic effect,laboratory examination index and complication rate were compared between the two groups.Results The total effective rate of the observation group was significantly higher than that of the control group(P＜0.05).There was no significant difference between the two groups(P＞0.05).The blood pH value,urinary pH value and formate(HCO2)in the observation group were significantly higher than those in the control group (P＜0.05).The serum K+,carcinoembryonic antigen(CEA)and leukocyte count(WBC)in the observation group were significantly lower than those in the control group (P＜0.05).The incidence of complications in the observation group was significantly lower than that in the control group (P＜0.05).Conclusion For patients with acute intestinal obstruction caused by colon cancer,the early one-stage resection can increase the index of blood pH value,urinary pH value and HCO2,reduce the serum K+,CEA and WBC as well as incidence rate of complications.This method is worthy of application and popularization. 2018 Vol. 25 (8): 58-60 [Abstract] ( 192 ) HTML (29 KB)  PDF  (0 KB)  ( 27 ) 61 Effect observation of Recombinant Human Endostatin Injection combined with chemotherapy in the treatment of middle and advanced non-small cell lung cancer ZHOU Yue-qiao ObjectiveToobservetheeffectofRecombinantHumanEndostatin(rh-ES)Injectioncombinedwithchemotherapy on treating middle and advanced non-small cell lung cancer(NSCLC).Methods A total of 60 patients with advanced non-small cell lung cancer admitted to our hospital from October 2015 to October 2016 were selected as the research objects.All patients were divided into control group and experimental group with 30 cases in each group by random color ball grouping method.The control group was treated with conventional chemotherapy,while the experimental group was treated with Recombinant Human Endostatin Injection combined with chemotherapy.The treatment effect,survival rate at different time periods(3,6,12 months)and incidence of adverse reactions were compared between the two groups.Results The total effective rate in the experimental group was significantly higher than that in the control group(P＜0.05).The 3-month survival rate was 96.67%(29/30)in the experimental group and 93.33%(28/30)in the control group(P＞0.05).The 6-month survival rate of the experimental group was 93.33%(28/30)and 12-month survival rate was 86.67%(26/30),which were higher than that of the control group 73.33%(22/30)and 63.33%(19/30),the differences were statistically significant(P＜0.05).The incidence of nausea and vomiting and platelet count in the experimental group were lower than those in the control group (P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion In the treatment of middle and advanced NSCLC patients,the combination of rh-ES injection and chemotherapy has a remarkable effect,which can prolong patient′s survival time and reduce the damage to the patient′s body,and is worthy of recommendation and clinical application in future. 2018 Vol. 25 (8): 61-63 [Abstract] ( 178 ) HTML (27 KB)  PDF  (0 KB)  ( 26 ) 64 Efficacy of neoadjuvant chemotherapy combined with laparoscopic surgery in the treatment of advanced colorectal cancer WANG Hua Objective To investigate the effect of neoadjuvant chemotherapy combined with laparoscopic surgery on advanced colorectal cancer.Methods Eighty-eight patients with advanced colorectal cancer admitted to our hospital from September 2014 to September 2016 were selected as the research object,and randomly divided into study group and reference group,with 44 cases in each group.The reference group was treated with laparoscopic surgery,while the study group was treated with neoadjuvant chemotherapy before laparoscopic surgery.The clinical effects and adverse reactions were compared between the two groups.Results There was no significant difference in the operation time between the two groups(P＞0.05).However,the anal exhaust time and hospitalization time in the study group were significantly shorter than those in the control group(P＜0.05).The recurrence rate,lymph node metastasis rate and complication rate in the study group were significantly lower than those in the control group (P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The application of neoadjuvant chemotherapy combined with laparoscopic surgery in the treatment of patients with advanced colorectal cancer can effectively improve the clinical efficacy,reduce the recurrence and metastasis rate,promote the recovery of patients,and the safety is relatively high,which is worthy of further clinical promotion. 2018 Vol. 25 (8): 64-66 [Abstract] ( 201 ) HTML (28 KB)  PDF  (0 KB)  ( 30 ) 67 Research of methods and ways of sex education for female adolescents with abortion in unmarried pregnancy WANG Xiao-ying;CHEN Wen-ju;YE Su-yun Looking back on the course of human development,the development of sex education was inevitably related to the fate of human beings.It can be proved that the purpose of sexual behavior restriction and education in human history was that sex education can restrict human sexual behavior and make eugenics possible.Secondly,it also protects human from STD.The sexual behavior is a kind of social behavior,which bears the behavior of morality and responsibility,ignoring the moral connotation of sexual behavior，and it will have serious consequences.Unmarried female teenage pregnancy is the result of reform and opening up in the sex field.Due to the lack of self knowledge,it results in onesided pursuit of enjoyment,resulting in unmarried pregnancy.In this paper,the methods and ways of sex education for women with abortion in unmarried pregnancy are discussed. 2018 Vol. 25 (8): 67-69转73 [Abstract] ( 144 ) HTML (33 KB)  PDF  (0 KB)  ( 37 ) 70 Clinical observation of cook cervical ripening double balloon and Oxytocin for labor induction and cervical ripening in term gestational women GONG Xiao-bin;RONG Li-yu;HU Shao-yi Objective To compare the efficacy and safety of of cook cervical ripening double balloon and Oxytocin for labor induction and cervical ripening in term gestational women.Methods 200 term pregnant women with induced labor indications from January 2016 to June 2017 in our hospital treated were selected as the research object,they were randomly divided into the observation group and the control group according to different abortion methods,100 cases in each group.The control group were received intravenous Oxytocin to promote cervical ripening and labor induction,the observation group were used cook balloon catheter for cervical ripening and labor induction,cervix bishop score were assessed before and after intervention,the effect of cervical ripening were evaluated,the delivery and complications were observed.Results The cervix Bishop score of the observation group and the control group after treatment were significantly that higher than those before intervention (P＜0.05),and after intervention,the cervix Bishop score of the observation group was higher than the control group,the difference was statistically significant(P＜0.05).The effect of cervical ripening and labor induction in the observation group was significantly higher than that the control group(P＜0.05).The labor time and production labor in the observation group were significantly shorter than those in the control group(P＜0.05)，the Vaginal delivery rate was significantly higher than that the control group(P＜0.05),the cesarean section rate was significantly lower than that the control group (P＜0.05)，the overall complication rate was significantly lower than the control group,the differences were statistically significant(P＜0.05).Conclusion The cook cervical ripening double balloon is safe,effective and simple method for cervical ripening and labor induction,The effect of cervical ripening and labor induction is better than that of drugs,and significantly reduce the incidence of cesarean section and complications,and ensure that mother and baby. 2018 Vol. 25 (8): 70-73 [Abstract] ( 160 ) HTML (31 KB)  PDF  (0 KB)  ( 34 ) 74 Comparison of the efficacy between Ethacridine alone and Mifepristone combined with Misoprostol and Mifepristone combined with Ethacridine in induction of labour in second trimester LI Zhong-hui;LIU Jiang-mei;LAI Zhu-yuan Objective To investigate the clinical efficacy of Ethacridine alone and Mifepristone combined with Misoprostol and Mifepristone combined with Ethacridine in induction of labour in second trimester.Methods The clinical data of 240 pregnant women with gestational age from 14 to 27 weeks who received induction of labor in second trimester in our hospital from February 2001 to December 2016 were retrospectively analyzed.According to the method of induction of labor,the patients were divided into 3 groups,80 cases in each group.The control group was given Ethacridine for labor induction,study group 1 was given Mifepristone combined with Misoprostol for induction of labor,and study group 2 was given Mifepristone combined with Ethacridine for induction of labor.The induction of labor,duration of labor induction,total labor time,volume of blood loss and placental residue were compared between the three groups of puerpera.Results The successful rate of induction of labor in the study group 1 and the study group 2 was significantly higher than that in the control group(P＜0.05).The duration of labor induction and total labor time in study group 1 and study group 2 were significantly shorter than those in the control group(P＜0.05).The proportion of the volume of blood loss＞150 ml in study group 2 and control group was significantly lower than that in study group 1(P＜0.05).The proportion of placental residue in study group 2 was significantly lower than that in control group and study group 1(P＜0.05).Conclusion Compared with Ethacridine alone,the duration of labor induction of Mifepristone combined with Misoprostol and Mifepristone combined with Ethacridine is short,with a high successful rate of induction of labor.Compared with Ethacridine alone and Mifepristone combined with Misoprostol,Mifepristone combined with Ethacridine has a higher safety. 2018 Vol. 25 (8): 74-76 [Abstract] ( 191 ) HTML (30 KB)  PDF  (0 KB)  ( 38 ) 77 The application value of home atomization inhaled glucocorticoids in the treatment of pediatric respiratory diseases MEI Wen-jing;ZOU Li;FANG Xing;HE Ying-hui;ZENG Xue-fei Objective To analyze the application value of home atomization inhaled glucocorticoids in the treatment of pediatric respiratory diseases.Methods Slected 90 cases of pediatric respiratory disease patient in our hospital from June 2015 to June 2017,and divided into routine group(45 cases)and experimental group(45 cases)randomly according to computer machine selection,the control group was received routine treatment,the experimental group was received the treatment of home atomization inhaled glucocorticoids.The improvement of clinical symptoms in the two groups was observed,and the family satisfaction and the total effective rate of treatment were analyzed and compared.Results The total effective rate of the treatment in the experimental group was 95.56% (43/45),the total effective rate of the treatment in routine group was 84.44%(38/45),the effect of experimental group was significantly higher than that the routine group,comparison between groups with statistical significance(P＜0.05).The experimental group both in the wheezing disappearance time,the chest symptoms disappearing time or breathing difficulties disappear time were shorter than that of the control group,comparison between groups with statistical significance(P＜0.05).The total satisfaction degree of the children in the experimental group was 95.56%,which was significantly higher than that of the control group (82.22%),and the differences were statistically significant(P＜0.05).Conclusion The use of home atomization inhaled glucocorticoids treatment in pediatric respiratory system disease can significantly improve the treatment rate of children,reduce and relieve the clinical symptoms of children,improve the overall treatment effect,it is worth promoting in clinical use. 2018 Vol. 25 (8): 77-79 [Abstract] ( 183 ) HTML (30 KB)  PDF  (0 KB)  ( 26 ) 80 Effect of Carboprost Tromethamine Injection and uterine cavity filling in the treatment of postpartum hemorrhage after caesarean section of placenta previa WEN Hai-yan;WANG Yan-yan;WANG Cai-hong Objective To investigate the effect of Carboprost Tromethamine Injection and uterine cavity filling in the treatment of postpartum hemorrhage after caesarean section of placenta previa.Methods From January 2016 to October 2017,76 cases of placenta previa and cesarean section were selected in our department of gynecology and obstetrics.They were randomly divided into experimental group and control group,38 cases in each group.The experimental group was given Carboprost Tromethamine Injection and uterine packing treatment,the control group was given simple Carboprost Tromethamine Injection treatment,were compared between the two groups after 2 and 24 h of bleeding,blood pressure,pulse and blood oxygen saturation.Results The amount of bleeding in the experimental group was less than that in the control group 2 and 24 hours after delivery.After intervention,the blood pressure,pulse and oxygen saturation index of the experimental group were better than those of the control group,and the differences were statistically significant(P＜0.05).ConclusionThe Carboprost Tromethamine Injection and uterine packing compared to give Carboprost Tromethamine Injection，can reduce the amount of bleeding of cesarean section for placenta previa puerperal,improve blood pressure,pulse and blood oxygen saturation,provide data and experience for the clinical application of this therapy. 2018 Vol. 25 (8): 80-82 [Abstract] ( 164 ) HTML (27 KB)  PDF  (0 KB)  ( 28 ) 83 Correlation analysis between premonitory abortion and CA125 and βhCG Levels CHEN Xiao-mei;LYU Hong-rui;JIANG Yan Objective To investigate the correlation between premonitory abortion and serum CA125 and β-hCG levels.Methods Altogether 24 cases of premonitory abortion patients who were treated in our hospital from April 2016 to December 2017 were selected as the observation group;while,24 normal pregnant women who were treated in our hospital in the same period were selected as the control group.The serum CA125 and β-hCG levels of two groups were detected by using electrochemilu minescence immunoassay(ECLIA)and compared;and the correlation between premonitory abortion and serum CA125 and β-hCG levels was analyzed.Results The serum CA125 level of the observation group was(41.32±3.98)IU/ml,obviously higher than that of control group(23.84±3.25)IU/ml,with statistically significant difference(P＜0.05);the serum β-hCG level of observation group was(10631.46±2024.68)mIU/ml,significantly lower than that of control group([18224.36±7135.57]IU/ml),with statistically significant difference(P＜0.05);premonitory abortion and serum CA125 and β-hCG levels were correlated to a certain degree(P＜0.05).Conclusion Pregnant women with premonitory abortion have higher serum CA125 level and significantly lower β-hCG level.Premonitory abortion is correlated with serum CA125 and β-hCG levels,which can provide a basis for clinical treatment. 2018 Vol. 25 (8): 83-85 [Abstract] ( 221 ) HTML (27 KB)  PDF  (0 KB)  ( 30 ) 86 The influence of free posture on the birth process and fetal orientation HUANG Li-Zhen Objective To study the clinical effect of free posture in the labor stage and fetal position.Methods Eighty-six puerpera delivered from October 2016 to October 2017 in our hospital were selected.The subjects were randomly divided into two groups,43 cases in each group.The control group was adopted the conventional delivery posture;the observation group was adopted the free delivery posture.The fetal position,delivery modes,labor stage and delivery outcomes were observed.Results The rate of occipitoanterior position and natural labor for observation group was significantly higher than that the control group;the rate of occipitotransverse position and transformation from natural labor to cesarean section for observation group was significantly lower than that in the control group (P＜0.05);the incubation period,active phase and second labor stage courses for observation group were significantly shorter than that in control group(P＜0.05);the rate of postpartum hemorrhage and neonatal asphyxia for two groups was not significantly different(P＞0.05);the incidence rate of cervical edema and dosage of oxytocin for observation group were significantly lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion The scientific free posture can greatly shorten the labor stage,reduce the dosage of oxytocin and improve the pregnancy outcomes. 2018 Vol. 25 (8): 86-88 [Abstract] ( 144 ) HTML (27 KB)  PDF  (0 KB)  ( 29 ) 89 Effectiveness of auditory brainstem response plus pure tone audiometry in the diagnosis and prognosis of sudden deafness JIANG Jun-he;ZHANG Song;YUAN Fo-liang;XING Hai-jie;DING Xiao-mei Objective To investigate the effectiveness of combination of application of auditory brainstem response(ABR)and pure tone audiometry(PTA)in the diagnosis and prognosis of sudden deafness.Methods Altogether 50 cases of patients with sudden deafness(53 ears)who were treated in our department from March 2016 to March 2017 underwent pure tone audiometry were selected,and their curve features included low frequency descent type (14 ears),high frequency descent type(13 ears),flat type(17 ears)and extremely severe type(9 ears).Corresponding treatment was given according to the different types,with 14 days for a course of treatment,and then the curative effect was determined.At the same time,ABR of sudden deafness patients was detected to observe the correlation between ABR threshold and subjective thresholds.The therapeutic effect was also observed between sudden hearing loss patients without ABR waveform(group A,15 ears)and with ABR waveforms(group B,38 ears).Results After treatment,17 ears of patients with sudden deafness were cured,14 ears showed effect and 8 ears were effective.The total effective rate of treatment was 73.58%.The threshold of group B patients with ABR waveforms was 10 to 20 dB which was higher than that of subjective threshold,with a good correlation(Y=1.8623-0.8741X,r=0.8741).The total effective rate of group A was 33.33%,and group B was 89.45%,with significant difference between the two groups(χ2=6.603,P=0.005).Conclusion Combination of application of ABR and PTA not only can be used for the diagnosis and classification of patients with sudden deafness,ABR also can be used as indicators to predict the prognosis of sudden deafness.Patients with ABR waveform have good treatment effect,while,patients without ABR waveform have bad treatment effect. 2018 Vol. 25 (8): 89-91转94 [Abstract] ( 138 ) HTML (30 KB)  PDF  (0 KB)  ( 28 ) 92 Application effect of oral orthodontic appliance in clinical practice ZHAO Yang Objective To study the application effect of oral orthodontic appliance in clinical practice.Methods A total of 50 patients with oral orthodontic treatment from February 2014 to February 2016 treated in our hospital were selected as the subjects.They were randomly divided into observation group and control group,25 cases in each group.The patients in the control group were treated with no bracketing stealth correction technique,and the patients in the observation group after treatment were treated with orthodontic appliance.The effect of the two groups were compared.Results The PAR scores of the two groups were significantly better than those before treatment,and the PAR scores of the observation group were better than that of the control group,the difference was statistically significant(P＜0.05).There was no significant difference between the two groups in the treatment of solid satisfaction(P＞0.05).The satisfaction degree of the comfort,the chewing function,the convenience and the language function of the control group were higher than those of the control group,the differences were statistically significant(P＜0.05).Conclusion The treatment of oral orthodontic appliance with oral orthodontic appliance is effective. 2018 Vol. 25 (8): 92-94 [Abstract] ( 134 ) HTML (27 KB)  PDF  (0 KB)  ( 23 ) 95 Study on conical beam CT of the characteristics of temporal-mandibular joints in the patients with unilateral complete cleft lip and palate XIE Qin;LIN Li;ZHANG Yu-hua;LI Duo;LIN Bin;LIN Shan Objective To investigate the characteristics of temporal-mandibular joint in the patients with unilateral complete cleft lip and palate by conical beam CT.Methods A total of 16 patients with unilateral complete cleft lip and palate (UCCLP)admitted to the Department of Stomatology Orthodontics in Fujian Medical University Union Hospital from June 2015 to June 2017 were selected as the study group.In addition,16 normal occlusal patients who underwent orthodontic treatment in the same period were selected as the control group.Both groups were given conical beam CT examination.CH,RH,H,W and other indexes were compared between the two groups,and CH/RH and H/W were calculated.At the same time,the condylar morphology of the two groups were compared.Results The CH,H,W,CH/RH and H/W at the healthy side in the study group were compared with those at the same side in the control group,and the differences were statistically significant (P＜0.05).There was no statistically significant difference in RH and H/W between the two groups (P＞0.05).The CH,H,W,CH/RH and H/W at ipsilateral side in the study group were compared with those in the control group,the differences were statistically significant (P＜0.05).There was no statistically significant difference in RH and H/W between the two groups(P＞0.05).The normal and abnormal condylar morphology at the healthy side in the study group was compared with that at the same side in the control group,the difference was statistically significant(χ2=28.571,P=0.000).The type of condylar morphology at the healthy side in the study group was compared with that at the ipsilateral side,the difference was statistically significant (χ2=16.667,P=0.000).Conclusion Conical beam CT has a higher diagnostic value in examining the characteristics of temporal-mandibular joint in the patients with unilateral complete cleft lip and palate.Compared with non-UCCLP healthy population,the condyles of UCCLP patients are short and its neck is narrow compared with mandibular ramus. 2018 Vol. 25 (8): 95-97转100 [Abstract] ( 120 ) HTML (31 KB)  PDF  (0 KB)  ( 27 ) 98 Clinical effect of orthodontics combined with repair therapy in the treatment of dentition defect complicated with dentognathic deformity GAO Yang;LI Hui-shan;LI Xiao-ming;WANG Ruo-li;WU Da-lei Objective To investigate the clinical efficacy of orthodontics combined with repair therapy in the treatment of dentition defect complicated with dentognathic deformity.Methods A total of 92 patients with dentition defect complicated with dentognathic deformity treated in Dalian Friendship Hospital from January 20,2015 to May 20,2016 were selected as the subjects,and divided into two groups by the order of admission,46 cases in each group.The routine group was given repair therapy alone,and the experimental group was further given orthodontic treatment.The therapeutic effect was compared between the two groups.Results The excellent and good rate of treatment in the experimental group(97.83%)was significantly higher than that in the routine group(82.61%),the difference was statistically significant(P＜0.05).The percentage of occlusion,teeth tidiness and anterior teeth overbite in the experimental group after recovery was significantly higher than that in the routine group,the difference was statistically significant(P＜0.05).The total treatment satisfaction in the experimental group was significantly higher than that in the conventional group,the difference was statistically significant(P＜0.05).Conclusion The application value of orthodontic therapy combined with repair therapy in the patients with dentition defect and dentognathic deformity is significant.The teeth function and aesthetic aspects have achieved a better recovery effect,which is worthy of adoption. 2018 Vol. 25 (8): 98-100 [Abstract] ( 164 ) HTML (28 KB)  PDF  (0 KB)  ( 39 ) 101 Comparison of application effect of immediate and delayed implant in maxillary anterior single tooth implant repair LI Jun-hong Objective To compare the effect of immediate and delayed implant in maxillary anterior single tooth implant repair.MethodsFrom April 2013 to May 2016,86 cases of maxillary anterior single tooth implant repair in our department were selected as the subjects.They were divided into study group (immediate planting,n=48)and control group(delayed planting,n=38)according to the different time of single tooth implant repair.The implant success rate,complication rate,red crown index(PES)score of 3 months and 6 months after crown restoration,and marginal bone resorption(MBL)at 3 months and 6 months after full crown restoration were compared between the two groups.Results There was no significant difference in the success rate between the study group(97.91%)and the control group(94.74%)(P＞0.05).There was no significant difference in the incidence of complications such as inflammation,gingival recession and metal exposure between the two groups(P＞0.05).The PES scores of the study group of patients with full crown after 3 months and 6 months was(11.98±1.25)points,(12.22±0.68)points,which was significantly higher than that of the control group of(9.06±1.20)points,(10.01±0.88)points(P＜0.05).There was no significant difference in the MBL after full crown restoration at 3 and 6 months between the two groups(P＞0.05).Conclusion Immediate implant and delayed implant have higher implant success rate in the maxillary anterior single tooth implant repair,and the marginal bone resorption of implant is similar,but the immediate implant is better than delayed planting in the aspect of aesthetics. 2018 Vol. 25 (8): 101-103 [Abstract] ( 162 ) HTML (30 KB)  PDF  (0 KB)  ( 26 ) 104 The application effect of magnetic attachment in prosthodontics LUO Jun Objective To investigate the application effect of magnetic attachment in prosthodontics.Methods 108 cases of dental patients treated in our hospital from October 2012 to November 2016 were selected as the subjects,and divided into two groups by random table method,with 54 cases in each group.The control group was treated with traditional residual root attachment prosthodontics,and the study group was treated with magnetic attachment oral repair.The treatment effects of the two groups were compared and analyzed.ResultsThe masticatory efficiency and fixation force of the patients between the two groups before oral rehabilitation were compared,and the differences were not statistically significant(P＞0.05).After repair,the masticatory efficiency and fixing force of the two groups increased,and the the masticatory efficiency and fixed force in the study group were higher than those in the control group,the differences were statistically significant(P＜0.05).Before the restoration,there was no significant difference in the scores of speech function,appearance and comfort between the two groups(P＞0.05).The speech function,appearance and comfort scores of the two groups increased with oral cavity repair,and the study group was higher than that of the control group,the difference was statistically significant(P＜0.05).The total satisfaction rate of the study group was 100.00%,and the control group was 79.63%,the difference was statistically significant(P＜0.05).Conclusion Application of magnetic attachments for dental patients can significantly improve the clinical efficacy,improve the speech function,appearance,patient comfort and satisfaction rate,optimize the indicators of the operation,and improve the early recovery of the patients confidence,which is worthy of widely used in clinic. 2018 Vol. 25 (8): 104-106 [Abstract] ( 158 ) HTML (27 KB)  PDF  (0 KB)  ( 29 ) 107 The advantages and disadvantages of Glass ion and composite resin combined repair or repair alone in wedge-shaped defect YANG Fen Objective To investigate the advantages and disadvantages of Glass ion and composite resin combined repair or repair alone in wedge-shaped defect.Methods Ninety wedge-shaped defect cases in our hospital from August 2015 to October 2016 were retrospectively analyzed,altogether 254 teeth.254 teeth were randomly divided into three groups according to the operation time.85 teeth in group A were filled with glass ions.89 teeth in group B were filled with composite resin.80 teeth in group C were filled with glass ions and composite resin.The dental pulp vitality,periodontal tissue stress and therapeutic effect before treatment and after treatment for 1 year were observed among the groups.Results There was no significant difference in pulp vitality between the three groups before treatment(P＞0.05).The percentage of normal pulp in group C(91.3%)was significantly higher than that in group A(69.4%)and B(69.7%)after treatment for 1 year,the difference was statistically significant(P＜0.05).The percentage of dental pulp degeneration in group C(1.2%)was significantly lower than that of group A(22.4%)and B(22.5%),the difference was statistically significant(P＜0.05).There was no significant difference between the A groups and B(P＞0.05).Conclusion The combination of glass ion and composite resin to repair wedge-shaped defects can effectively prevent the filler from falling off,protect the pulp,reduce periodontal stress.It is better than single use,which is worthy to clinical promotion. 2018 Vol. 25 (8): 107-109 [Abstract] ( 151 ) HTML (28 KB)  PDF  (0 KB)  ( 30 ) 110 Analysis on the optimal time of clinical surgical treatment in patients with diabetic cataract and its therapeutic effect QU Zheng-peng;YANG Ling Objective To analyze the optimal time of clinical surgery for patients with diabetic cataract and its therapeutic effect.Methods From April to November in 2017,168 patients suffering from diabetic cataract treated in the Bayuquan Bohai Aier Eye Hospital,Yingkou City were selected as research objects.According to different time points of the surgeries,they were divided into three groups,group A(n=72)had cataract surgery when fasting blood glucose＜5.9 mmol/L),group B(n=66)had cataract surgery when fasting blood glucose ranging from 6.0 mmol/L to 7.0 mmol/L,and group C(n=30)had cataract surgery when fasting blood glucose maintaining 7.1-8.0 mmol/L.Vision recovery before and after treatment was compared in all patients.The occurrence of complications among three groups was analyzed.Results The vision were all improved after surgeries in all patients compared with that before treatment,with a significant difference(P＜0.05).The incidence of complications in group C(86.67%)was higher than that in group A and B,with statistical significance (P＜0.05).Conclusion Surgical treatment for diabetic cataract patients should select an appropriate timing based on the fasting blood glucose level,which can effectively improve the vision and reduce the incidence of complications. 2018 Vol. 25 (8): 110-112 [Abstract] ( 189 ) HTML (27 KB)  PDF  (0 KB)  ( 29 ) 113 The block effect of Dexmedetomidine combined with Ropivacaine in the external bundle posterior bundle and internal bundle of subclavian brachial plexus JIANG Qi;YANG Jin-hui;ZHOU Li-hua;XIN Dian;WU Bao-hua Objective To investigate the block effect of Dexmedetomidine combined with Ropivacaine in the external bundle,posterior bundle and internal bundle of subclavian brachial plexus.Methods From June 2015 to June 2016,58 patients who underwent orthopedic surgery under the elbow joint of upper extremity in our hospital were randomly divided into two groups,dexmedetomidine combined ropivacaine group(DR group)and pure ropivacaine group(R group),29 cases in each group.The two groups were positioned 2 cm below the coracoid process.After the nerve stimulator induced the external bundle,the posterior bundle and the internal bundle,the DR group and the R group were injected with 0.5 μg/kg of Dexmedetomidine combined with 150 mg of Ropivacaine and 150 mg of Ropivacaine,with a capacity of 30 ml.Each bundle was injected with 10 ml.Postoperative sensory and motor block and intraoperative comfort rating were recorded in both groups.The incidence of adverse reactions was recorded in both groups.Results There was no significant difference in motor block time between the two groups(P＞0.05).The onset time,onset time and duration of motor block in DR group were better than those in R group (P＜0.01).The proportion of comfort grade 1(100.0%)in DR group was higher than that in R group (86.2%),the difference was statistically significant(P＜0.05).There were no adverse reactions such as bradycardia,hypotension,respiratory depression,nausea and vomiting between the two groups(P＞0.05).Conclusion Dexmedetomidine can shorten the onset time of anesthesia and prolong the duration of sensory block,and improve the comfort during the surgery. 2018 Vol. 25 (8): 113-115转119 [Abstract] ( 166 ) HTML (31 KB)  PDF  (0 KB)  ( 40 ) 116 Effect comparison of the diluent Propofol and high concentration Propofol on painless induced abortion WANG Yong;HE Chun-yan Objective To observe the efficacy,side effects and dosage of diluent Propofol(0.5%)and high concentration Propofol(1%)for painless induced abortion so as to discuss the superiority of the concentration of two narcotic drugs.Methods From August 2016 to July 2017,100 cases of early pregnancy women who voluntarily requested painless artificial abortion were randomly divided into diluted Propofol group (0.5%concentration,Propofol 200 mg/20 ml+normal saline 20 ml,referred to as the observation group).High concentration Propofol group (1%concentration,Propofol 200 mg/20 ml,no dilution,referred to as the control group),50 cases in each group,the anesthetic effect and adverse reactions were compared between the two groups.Results The incidence of blood pressure decreased significantly,the incidence of heart rate decreased significantly in the operation,the incidence of oxygen saturation decreased significantly in the operation in the observation group were less than those in the control group,the difference was statistically significant(p＜0.05),the average dosage of Propofol in the observation group surgery was less than the control group,the difference was statistically significant(P＜0.05),the incidence of obvious injection pain when Propofol injection in the observation group surgery was less than the control group,the difference was statistically significant(p＜0.05),In the observation group,the time from the end of drug injection to the wake-up time and the time from the end of drug injection to the recovery of free walking were shorter than those in the control group （P＜0.05）.There was no significant difference between the two groups in the incidence of intraoperative and postoperative adverse reactions and operation time （P＜0.05).Conclusion Application of Propofol in painless induced abortion operations has the advantages of stable hemodynamics,low incidence of injection pain and respiratory depression,less Propofol dosage,and shorter recovery time,which can achieve an ideal anesthesia effect. 2018 Vol. 25 (8): 116-119 [Abstract] ( 167 ) HTML (30 KB)  PDF  (0 KB)  ( 32 ) 120 Effect of Lidocaine Ointment combined with Pregabalin Capsule in the treatment of postherpetic neuralgia LUO Ning;LU Hui Objective To investigate the effect of Lidocaine Ointment combined with Pregabalin Capsules in the treatment of postherpetic neuralgia.Methods From January 2016 to July 2017,84 patients with postherpetic neuralgia were selected and randomly divided into single therapy group and combined therapy group,42 cases in each group.The single therapy group was treated with Lidocaine Ointment alone,and the combined therapy group was treated with Lidocaine Ointment combined with Pregabalin Capsules.The recovery rate of postherpetic neuralgia was compared between the two groups.The disappearance time of postherpetic neuralgia;degree of postherpetic neuralgia,mental health,social function and sleep status of patients before and after intervention were also compared.Results The recovery rate of postherpetic neuralgia in combination therapy group was higher than that in single therapy group，the difference was statistically significant(P＜0.05).In the degree of postherpetic neuralgia,mental health,social function and sleep，there was no significant difference between the two groups(P＞0.05).The degree of postherpetic neuralgia,mental health level,social function and sleep status in the combined therapy group were better than those in the single therapy group，the difference was statistically significant(P＜0.05).The disappearance time of postherpetic neuralgia was （15.51±1.41） d in combination therapy group,which was shorter than that in single therapy group of （24.42±2.77） d，the difference was statistically significant(P＜0.05).Conclusion The effect of Lidocaine Ointment combined with Pregabalin Capsules in the treatment of postherpetic neuralgia is exact,which can effectively relieve pain,shorten the course of disease,accelerate the recovery of patients and promote the quality of life of patients,which is worth popularizing and applying. 2018 Vol. 25 (8): 120-122 [Abstract] ( 183 ) HTML (28 KB)  PDF  (0 KB)  ( 31 ) 123 Application value analysis of femoral nerve block anesthesia in knee joint surgery in grass-roots hospital ZHOU Wan-fang Objective To explore the application value of femoral nerve block anesthesia in knee joint operation in primary hospitals.Methods Sixty patients with knee joint surgery from January 2016 to August 2017 in our hospital were randomly divided into femoral nerve block group (femoral nerve group)and lumbar combined block anesthesia group(control group),30 cases in each group.In the control group,combined spinal-epidural anesthesia was used,while in the femoral nerve group,femoral nerve block anesthesia was applied.The anesthetic effect of two groups performed with knee surgery was compared.The time of analgesia maintenance,hemodynamic indexes before and after intervention,incidence of adverse reactions including nausea and vomiting,and urine retention were compared.Results In the two groups,the anesthetic effects were satisfactory without statistical difference in blocking (P＞0.05).In the femoral nerve group,time to maintain anesthesia was longer than that in the control group(P＜0.05).The hemodynamic indexes before the intervention were similar(P＞0.05),but after anesthesia,the hemodynamic indexes in the femoral nerve group were superior to those in the control group (P＜0.05).The incidence of adverse reactions like nausea and vomiting,and urinary retention in the femoral nerve group was lower than that of the control group(P＜0.05).Conclusion Femoral nerve block anesthesia has a high application value in knee surgery.It can effectively improve the analgesic effect,maintain long-term analgesia and hemodynamic stability,and reduce the occurrence of adverse reactions,which is worthy of promotion and application. 2018 Vol. 25 (8): 123-125 [Abstract] ( 162 ) HTML (27 KB)  PDF  (0 KB)  ( 29 ) 126 Clinical effect observation of fast-track anesthesia for the heart in cardiac surgery SHI Jing-Feng;HAN Jing-tian Objective To investigate the clinical effect of fast-track anesthesia on the heart in cardiac surgery.Methods A total of 138 patients undergoing cardiac surgery from May 2015 to July 2017 in our hospital were selected as research subjects.The participants were divided into observation group and reference group by a random number table method,with 69 cases in each group.Patients in the reference group were anesthetized by conventional anesthesia,while in the observation group,the fast-track anesthesia was adopted.The analgesic effect,alertness-sedation score(OAA/S),awake time,extubation time,hospital stay in intensive care unit(ICU)and the changes of hydrodynamic indicators were compared in the two groups.Results The analgesic effect and OAA/S score in the observation group were significantly better than those in the reference group,the difference was statistically significant(P＜0.05).The awake time,extubation time and ICU stay in the observation group were significantly shorter compared with those in the reference group with significant differences (P＜0.05).Perioperative hemodynamic performance was stable in both groups without significant changes at various time points,there was no significant difference (P＞0.05).Conclusion The application of fast-track anesthesia on the heart in cardiac surgery has a good anesthetic effect,which can shorten the awake time and rehabilitation time of patients in high safety,and is worthy of clinical promotion. 2018 Vol. 25 (8): 126-128 [Abstract] ( 163 ) HTML (28 KB)  PDF  (0 KB)  ( 27 ) 129 Effect evaluate of Montelukast Sodium assisted Azithromycin in the treament of pediatric asthmatic bronchitis WANG Zhen-ni;XIAO Xiao-dong;GONG Wei-ming Objective To evaluate the effect of Montelukast assisted Azithromycin in the treatment of pediatric asthmatic bronchitis.Methods A total of 120 children with asthmatic bronchitis treated in our hospital from January 2016 to October 2017 were selected as subjects and divided into the single drug group and combination group according to random number table method,60 in each group.The single drug group were given Azithromycin alone and the combination group was treated with Montelukast Sodium assisted Azithromycin.The therapeutic effect,symptom relief time,the index of hypersensitive C-reactive protein (hsCRP)and the incidence of adverse reactions of two groups were compared.Results After treatment,the total effective rate of the children in the combination group (95.00%)was higher than that of the single drug group(78.33%),and the difference was statistically significant(P＜0.05).The relief time of cough,wheezing,wheezing sound,the temperature dropped to the normal range and hospitalization days of the children in the combination group were significantly shorter than those in the single drug group,and the differences were statistically significant(P＜0.05).After treatment,two groups of children with hypersensitive C-reactive protein levels were lower than before treatment,and combination group with hypersensitive C-reactive protein levels were lower than that in the single drug groups,the differences were statistically significant(P＜0.05).The incidence of adverse reactions of the children in the combination group(3.33%)was lower than that of the single drug group(18.33%),and the difference was statistically significant(P＜0.05).Conclusion Montelukast Sodium is a good adjuvant for the treatment of asthmatic bronchitis,it can improve the clinical efficacy.The improvement of various symptoms is rapid,and the incidence of adverse reactions low,with safety and reliability. 2018 Vol. 25 (8): 129-131 [Abstract] ( 193 ) HTML (30 KB)  PDF  (0 KB)  ( 35 ) 132 Clinical effect observation of Acitretin Capsules combined with Xiyanping in the treatment of plaque psoriasis ZHAO Hui-ping Objective To explore the clinical effect of Acitretin Capsules combined with Xiyanping in the treatment of plaque psoriasis.Methods 120 patients with plaque psoriasis treated in department of dermatology in our hospital from April 2016 to April 2017 were selected as subjects and randomly divided into two groups,60 cases in each group.The control group was treated with Acitretin Capsule,the observation group was treated with Acitretin Capsules combined with Xiyanping.The clinical efficacy,symptom improvement,levels of various factors and adverse reactions of the two groups were compared.Results The effective rate of treatment in the observation group was 93.33%,which was significantly higher than 71.67%in the control group,and the difference was statistically significant(P＜0.05).The PASI score in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The levels of TNF-α,RANTES and MCP-1 in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups of patients(P＞0.05),such as dry mouth,dry skin itching,elevated transaminase and elevated blood fat.Conclusion Acitretin Capsules combined with Xiyanping in the treatment of plaque psoriasis has a significant clinical effect,can effectively improve the skin symptoms,reduce the level of inflammatory factors,shorten the treatment cycle,and the incidence of adverse reactions is low.It has positive clinical significance. 2018 Vol. 25 (8): 132-134转138 [Abstract] ( 176 ) HTML (31 KB)  PDF  (0 KB)  ( 29 ) 135 Clinical efficacy of Nimodipine in the treatment of cognitive impairment caused by cerebrovascular diseases QIU Hai-feng Objective To analyze the clinical effect of Nimodipine in the treatment of cognitive impairment caused by cerebrovascular diseases.Methods A total of 100 patients with cognitive impairment caused by cerebrovascular diseases who were admitted into our hospital from June 2014 to June 2017 were selected as subjects.They were evenly divided into two groups by the random number table method,50 cases in each group.In control group,routine treatment was used,while in the research group,Nimodipine was added on this basis.The simple mental state scale (MMSE)score,the daily activity ability scale (ADL)score before and after treatment,the clinical treatment effect and adverse reactions of the two groups were observed and compared.Results Before treatment,the MMSE and ADL scores of the research group were compared with the control group,and the differences were not statistically significant(P＞0.05).After treatment,the MMSE score of patients in the research group was(25.6±2.6)points,which was significantly higher than that of the control group of(21.3±1.9)points,the ADL score of patients in the research group was(27.8±3.5)points,which was lower than that in the control group of(38.2±4.1)points,and the differences were statistically significant(P＜0.05).The total effective rate of patients in the research group was 96.0%,which was significantly higher than 80.0%in the control group,and the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the research group was 4.0%,which was less than 18.0%in the control group,and the difference was statistically significant(P＜0.05).Conclusion The application of Nimodipine in patients with cognitive impairment caused by cerebrovascular diseases can effectively alleviate patients′symptoms,ameliorate the quality of life,and improve the clinical effect in high safety,which can be promoted. 2018 Vol. 25 (8): 135-138 [Abstract] ( 166 ) HTML (32 KB)  PDF  (0 KB)  ( 27 ) 139 Clinical effect of Conjugated Estrogens Ointment combined with Baofukang Gel in the treatment of elderly diabetic vaginitis ZHANG Jing Objective To investigate the clinical effect of Conjugated Estrogens Ointment combined with Baofukang Gel in the treatment of elderly diabetic vaginitis.Methods From March 2016 to December 2017,54 cases of elderly diabetes vaginitis patients treated in our hospital were selected as the study subjects,and the random number table method was used to divide them into the comparison group and the research group,with 27 cases in each group.The patients in the comparison group were treated with Conjugated Estrogens Ointment alone,and patients in the research group were treated with the Conjugated Estrogens Ointment combined with Baofukang Gel.The total score of clinical manifestations of the two groups before and after treatment was compared,the clinical treatment effect and adverse reaction of the two groups after treatment were also compared.Results Before treatment,the total score of clinical manifestations was compared between the two groups,and the difference was not statistically significant(P＞0.05),after treatment,the total score of clinical manifestations of the research group were significantly lower than those of the control group and before treatment,the differences were statistically significant(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The combination of Estrogen Ointment and Baofukang Gel in the treatment of senile diabetic vaginitis can effectively improve the clinical symptoms and control the disease. 2018 Vol. 25 (8): 139-141 [Abstract] ( 176 ) HTML (29 KB)  PDF  (0 KB)  ( 31 ) 142 Clinical effect evaluation of Thymosin combined with antituberculosis drugs in the treatment of multi-drug resistant tuberculosis XU Jiang-tao;HU Xiao-hong;WANG Yu-min Objective To investigate the therapeutic effect of Thymosin combined with antituberculosis drugs in the treatment of multi-drug resistant tuberculosis.Methods From December 7,2015 to January 1,2017,68 patients with multi-drug resistant tuberculosis treated in Shenyang Chest Hospital were selected as subjects.They were evenly divided into two groups according to the complete random principle,34 cases in each group.according to different treatment methods.In the control group,conventional anti-tuberculosis drug treatment was used,while on the basis of the control group,Thymosin was added in the observation group.The biochemical indicators,sputum negative conversion,cavity closure and occurrence of adverse events were observed.Results There was no statistically significant difference between the two groups of patients before and after treatment of hemoglobin,alanine transaminase and urea nitrogen levels(P＞0.05).Treatment for 3 months,treatment for half year and end of treatment,the rates of sputum negative conversion in the observation group(52.94%,64.71%,73.53%)were higher than those of the control group(29.41%,38.24%,44.12%),and the differences were statistically significant(P＜0.05).Treatment for 3 months and end of treatment,the rates of cavity closure in the observation group(29.41%,55.88%)were higher than those of the control group(5.88%,32.35%),and the differences were statistically significant(P＜0.05),while there was no statistically significant difference of the cavity closure rate between two groups of treatment for half year(P＞0.05).There was no statistically significant difference in the incidence of adverse events between the two groups (P＞0.05).Conclusion In the treatment of multi-drug resistant tuberculosis,anti-tuberculosis drugs combined with Thymosin has a great effect,which can significantly alleviate the disease condition and promote the recovery in high safety. 2018 Vol. 25 (8): 142-144转148 [Abstract] ( 145 ) HTML (30 KB)  PDF  (0 KB)  ( 28 ) 145 Effect of Ketotifen orally combined with Tanreqing atomization inhalation in treatment of senile patients with post-infectious cough LI Chang-juan Objective To observe the clinical effect of Ketotifen orally combined with Tanreqing atomization inhalation in treatment of senile patients with post-infectious cough (TIC).Methods A total of 86 senile patients with TIC treated in our hospital from January 2015 to June 2017 were selected as subjects and divided into the control group and the observation group according to the random digital table method,with 43 cases in each group.The control group was treated with oral Ketotifen,and the observation group was treated with Tanreqing atomization inhalation on the basis of the control group.Trentment course lasted for 2 weeks of the two groups.The clinical effects,total points of the cough symptom before and after treatment and the adverse reaction of the two groups were compared.ResultsThe total effective rate of the patients in the observation group (95.3%)was significantly higher than that in the control group(81.4%),and the difference was statistically significant(P＜0.05).The total points of the cough symptom of patients in the two groups 1 and 2 weeks after treatment were lower than before the treatment,the total points of the cough symptom of patients in the observation group were significantly lower than those in the ontrol group,and the differences were statistically significant(P＜0.05).The incidence of adverse reactions in the control group was 9.3%,while it was 11.6%in the observation group,the incidence of adverse reactions in the two groups was not statistically significant(P＞0.05).Conclusion The curative effect of Ketotifen orally combined with Tanreqing atomization inhalation in the treatment of PIC is better than Ketotifen monotherapy,and the side effects are similar.It is worth spreading. 2018 Vol. 25 (8): 145-148 [Abstract] ( 165 ) HTML (32 KB)  PDF  (0 KB)  ( 35 ) 149 Clinical effect of Aspirin Enteric-Coated Tablets combined with Clopidogrel in treatment of angina pectoris of coronary heart disease MA Di-hui Objective To explore the clinical effect of Aspirin Enteric-Coated Tablets combined with Clopidogrel in treatment of angina pectoris of coronary heart disease.Methods Altogether 94 cases of patients with angina pectoris of coronary heart disease who were treated in our hospital from January 2016 to October 2017 were selected as the subjects of this research and divided into observation group and control group according to the randomized number method,with 47 cases in each group.Patients in control group were treated only with Aspirin Enteric-Coated Tablets treatment,patients in the observation group were treated with Clopidogrel and Aspirin Enteric-Coated Tablets,the continuous medication was given for 4 weeks.The changes of angina pectoris symptom index,plasma fibrinogen,plasma viscosity and total blood viscosity levels were compared between the two groups before and after treatment.Results After treatment,the interval of angina attack was longer than before treatment,the number of attacks was less than before treatment,the duration was shorter than before treatment,and the differences were statistically significant(P＜0.05).The interval of angina attack of patients in the observation group was longer than that in the control group,the number of attacks of patients in the observation group was less than that in the control group,the duration of patients in the observation group was shorter than that in the control group,and the differences were statistically significant(P＜0.05).After treatment,the plasma fibrinogen,plasma viscosity and total blood viscosity were lower than before treatment,and the differences were statistically significant(P＜0.05).The plasma fibrinogen,plasma viscosity and total blood viscosity of the patients in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Combination of application of Aspirin Enteric-Coated Tablets and Clopidogrel is effective in the treatment of angina pectoris.It can effectively improve the symptoms of angina pectoris and regulate plasma fibrinogen,plasma viscosity and whole blood viscosity level,which is worthy of clinical promotion and application. 2018 Vol. 25 (8): 149-151转154 [Abstract] ( 146 ) HTML (31 KB)  PDF  (0 KB)  ( 35 ) 152 Clinical effect of Edaravone Injection combined with Danhong conducting acupoint injection in the treatment of cerebral infarction GAO Shuang Objective To investigate the clinical effect of Edaravone Injection combined with Danhong conducting acupoint injection in the treatment of cerebral infarction.Methods 80 patients with cerebral infarction treated in our hospital from September 2014 to May 2017 were enrolled and they were randomly divided into control group and observation group with 40 cases in each group using the complete random method.Patients in the control group were treated with Edaravone Injection,while in the observation group,Danhong conducting acupoint injection was added besides treatment in the control group.The therapeutic effect and total satisfaction rate between the two groups were compared.Results After three weeks of treatment,the score of neurological deficit in the observation group was significantly lower than that in the control group (P＜0.05).The total effective rate in the observation group was 92.50%,which was significantly higher than that in the control group(72.50%)(P＜0.05).The total satisfaction rate of treatment in the observation group was significantly higher compared with that in the control group(P＜0.05).Conclusion Edaravone Injection combined with Danhong conducting acupoint injection in the treatment of cerebral infarction can effectively improve the therapeutic effect. 2018 Vol. 25 (8): 152-154 [Abstract] ( 177 ) HTML (27 KB)  PDF  (0 KB)  ( 30 ) 155 Effect observation of self-made Tongjing Huoluo Powder combined with acupoint massage treating hypertension LI Zhi-dan Objective To observe the clinical effect of self-made Tongjing Huoluo Powder combined with acupoint massage treating hypertension.Methods From May 2016 to June 2017,140 patients with hypertension treated in our hospital were selected as the observation subjects.The patients were divided into the control group and observation group using the random number table method,and there were 70 cases in each group.Patients in the control group were given single acupoint massage,while the observation group was given oral self-made Tongjing Huoluo Powder on the basis of the control group.The treatment effect between the two groups were compared.Results There was no significant difference in systolic blood pressure and diastolic blood pressure between the two groups before treatment(P＞0.05).After treatment,the systolic pressure of the two groups was lower than that before treatment,and the diastolic pressure of the observation group was lower than that before the treatment,and the difference was statistically significant(P＜0.05).The systolic and diastolic pressure of the observation group were lower than that of the control group,and the difference was statistically significant(P＜0.05).The total effective rate of the patients in the observation group was 81.4%,which was significantly higher than that of the control group (68.6%),and the difference was statistically significant(P＜0.05).Conclusion The effect of self-made Tongjing Huoluo Powder combined with acupoint massage treating hypertension is better than that of acupoint massage alone. 2018 Vol. 25 (8): 155-157 [Abstract] ( 146 ) HTML (29 KB)  PDF  (0 KB)  ( 24 ) 158 Effect of Bushen Huoxue traditional Chinese medicine in the treatment of hyperosteogeny secondary low back pain and influence on bone sclerosis protein level of patients WANG Zai-feng Objective To investigate the effect of Bushen Huoxue traditional Chinese medicine in the treatment of hyperosteogeny secondary low back pain and influence on bone sclerosis protein(SOST)level of patients.Methods Eighty cases of patients with hyperosteogeny secondary low back pain from May 2015 to May 2017 treated in our station were randomly selected,and patients were divided into the single Western Medicine group (n=40)and Western Medicine combined with Chinese herbal group(combination of Traditional Chinese and Western Medicine group,n=40)according to the treatment methods.TCM syndrome score,clinical effect and SOST level were compared in patients between the two groups were compared.Results The score of joint and muscle pain,soreness and weakness of waist and knees,unfavourable flexion and extension,intolerance to cold and cold limbs,weak or breakdowning pulse,thin white or atrazine coating on the tongue in patients of combination of Traditional Chinese and Western Medicine group were significantly lower than those of single Western Medicine group(P＜0.05),and the total effective rate(90.0%)was significantly higher than that of the Western Medicine group(40.0%)(P＜0.05),and the level of SOST was significantly higher than that of the single Western Medicine group(P＜0.05).ConclusionThe effect of Bushen Huoxue traditional Chinese medicine in the treatment of hyperosteogeny secondary low back pain is significant,and it can effectively raise the SOST level of patients. 2018 Vol. 25 (8): 158-160 [Abstract] ( 148 ) HTML (27 KB)  PDF  (0 KB)  ( 29 ) 161 Clinical effect of modified Xiaoyan Lidan Decoction combined with laparoscopic surgery treating cholecystitis complicated with cholelithiasis SHI Hong-wei;ZHANG Shu-yue;LIN Bin Objective To explore the clinical effect of modified Xiaoyan Lidan Decoction combined with laparoscopic surgery treating cholecystitis complicated with cholelithiasis.Methods From January 2015 to February 2016,100 patients suffering from cholecystitis complicated with cholelithiasis admitted into our hospital were selected.They were randomly divided into the control group(laparoscopic surgery)and observation group(modified Xiaoyan Lidan Decoction combined with laparoscopic surgery).Results The total effective rate of the observation group was 98.00%,which was higher than that in the control group(74.00%)(P＜0.05).After treatment,the symptomatic score and analgesic usage rate in the observation group were significantly lower than those in the control group.Frequency of using analgesic drugs was(1.21±0.01)times in the observation group,which was significantly fewer than that in the control group([9.21±0.05]times)(P＜0.05).Conclusion The effect of modified Xiaoyan Lidan Decoction combined with laparoscopic surgery treating cholecystitis complicated with cholelithiasis is significant. 2018 Vol. 25 (8): 161-162转166 [Abstract] ( 169 ) HTML (26 KB)  PDF  (0 KB)  ( 42 ) 163 Effect of Shenqi Gualou Xiebai Banxia Decoction and XiaoKe Decoction combined with Western Medicine treating coronary heart disease complicated with diabetes with type deficiency of both qi and yin and intermingled phlegm and blood stasis JIA Peng;GAN Yu;LU Yun-zhao;CHEN Sheng-ye;FAN Ming-shi Objective To study the influence of integrated traditional Chinese medicine and Western Medicine on the life quality and related physical and chemical indexes in patients with coronary heart disease complicated with diabetes with type deficiency of both qi and yin and intermin-gled phlegm and blood stasis.Methods One hundred and twenty patients with coronary heart disease complicated with diabetes with type deficiency of both qi and yin and intermingled phlegm and blood stasis treated in our hospital from January 2016 to April 2017 were selected as the research object.The patients were divided into the Western Medicine group (n=60)and integrated traditional Chinese medicine and Western Medicine group(combination group,n=60)according to the random number table method.The Western Medicine group was treated with Metformin Hydrochloride Sustained Release Tablets combined with Isosorbide Mononitrate Tablets,while the combination group was treated with Shenqi Gualou Xiebai Banxia Decoction and XiaoKe Decoction on the basis of the Western Medicine.The fasting blood glucose,postprandial 2 h blood glucose,total cholesterol,three glycerol,blood pressure and quality of life score were compared between the two groups.Results The improvement of fasting blood glucose,postprandial 2 h blood glucose,total cholesterol,triglyceride,blood pressure and quality of life score in the two groups were better than those before treatment,and the difference was statistically significant(P＜0.05).The improvement degree of fasting blood glucose,postprandial 2 h blood glucose,total cholesterol,three triglyceride,blood pressure and quality of life score of the combined group were significantly higher than those of the western medicine group and the difference was statistically significant(P＜0.05).Conclusion The integrated traditional Chinese medicine and Western Medicine treatment can improve the quality of life and achieve good clinical effect and control the development of the coronary heart disease complicated with diabetes. 2018 Vol. 25 (8): 163-166 [Abstract] ( 155 ) HTML (30 KB)  PDF  (0 KB)  ( 36 ) 167 Investigation and analysis on the knowledge situation of “the hierarchical diagnosis and treatment guidelines of obstetrics and gynecology in Sichuan Province(2016)” YANG Ye;XIANG Xiao-li; XIAN Ming;SHU Yan;LIU Lu Objective To understand the knowledge of the obstetricians in Sichuan Province about“the hierarchical diagnosis and treatment guidelines of obstetrics and gynecology in Sichuan Province(2016)”，and to provide reference for the health administrative departments,medical institutions to make relevant decisions.Methods From May 2017 to July 2017,a random digital table method was used to extract 2147 obstetricians from obstetrical medical staff in 21 cities and states of Sichuan province.The questionnaire survey was carried out in the form of self-made questionnaire,and the knowledge of“the hierarchical diagnosis and treatment guidelines of obstetrics and gynecology in Sichuan Province(2016)”and the relevant knowledge of it were statistically analyzed.Results In the 2147 questionnaires,the effective questionnaires were 2015,with an effective rate of 93.85%.The rate of awareness of the“the hierarchical diagnosis and treatment guidelines of obstetrics and gynecology in Sichuan Province(2016)”in the survey was 82.7%,and the overall awareness of the “the hierarchical diagnosis and treatment guidelines of obstetrics and gynecology in Sichuan Province(2016)”was 75.7%.The awareness rate of the first diagnosis mechanism of difficult disease and critically ill,high-risk pregnant women referral accompany was low,which were 61.4%and 34.8%respectively.Conclusion Obstetric medical staff in Sichuan province have a high awareness of the “the hierarchical diagnosis and treatment guidelines of obstetrics and gynecology in Sichuan Province (2016)”,from knowing to master and scientific application there is still a certain gap.It is suggested that the government should provide more learning opportunities.The hospital should create a good atmosphere for learning and further enhance the training of grassroots medical personnel in the “the hierarchical diagnosis and treatment guidelines of obstetrics and gynecology in Sichuan Province(2016)”,to apply the guidelines scientifically and further ensure the safety of mother and children. 2018 Vol. 25 (8): 167-169 [Abstract] ( 143 ) HTML (32 KB)  PDF  (0 KB)  ( 33 ) 170 Survey of prevalence and Cognition of metabolic syndrome among bus drivers in Jiangmen city ZHONG Ya;DING Zhi-jun;ZHANG Lu;LI Lin;TANG Bing;LI Ai-ai;CHEN Mu-lan Objective To investigate the prevalence of metabolic syndrome(MS)and the cognition of disease among bus drivers in Jiangmen.Methods From March 2015 to December 2016,310 cases of bus driver in Jiangmen had the physical examination in our hospital were selected as the research objects.According to the results of the examination,the prevalence of MS was analyzed,and the questionnaire was used to investigate the cognition status of MS disease.Results Among the 310 bus drivers,76 cases were diagnosed with MS.The prevalence rate was 24.51%,with the highest detection rate of central obesity (26.45%).The prevalence of MS and its various components,such as central obesity,hyperglycemia,hypertension and TG abnormality were increased gradually with age (P＜0.05).The cognition of MS among bus driver in Jiangmen city was generally low,only the understanding proportion of“hazards of high blood pressure and high blood sugar”was more than 30%,the understanding proportion of other items were all less than 30%.Conclusion The prevalence of MS among bus drivers in Jiangmen city is high,but the cognition of disease is generally low.Therefore,it is necessary to strengthen the health education of disease,improve the understanding of disease related knowledge and establish a healthy lifestyle so as to reduce the incidence of metabolic syndrome and related diseases. 2018 Vol. 25 (8): 170-172 [Abstract] ( 153 ) HTML (27 KB)  PDF  (0 KB)  ( 34 ) 173 Application effect of community continuity nursing in patients with cerebral apoplexy HE Cai-xia;CAO Jing;HUANG Chu-zhen;TANG Xiao-na;BI Shang-qing;LUO Zhen-yu;ZHANG Pan;WANG Shu-yuan Objective To explore the application effect of community continuity nursing in stroke patients.Methods From October 2015 to July 2016,110 patients with stroke in Baoan Traditional Chinese Medicine Hospital were evenly divided into control group and the research group according to the discharge order,with 55 cases in each group.In the control group,routine nursing such as family care after discharge was used.In the research group,on the basis of the routine nursing,community continuity nursing was provided.The nursing effect of the two groups was observed.Results After discharge,the compliance scores of regular drug administration,reasonablediet,return visit on schedule,and periodic exercise in the research group were all higher than that those in the control group with statistical differences(P＜0.05).The scores of the quality of nursing staff,nursingattitude,nursing service content,and nursing satisfaction by patients in the research group were significantly higher than that in the control group （P＜0.05）.In the research group，the BI index scores in the 1，3，and 6-months nursing after discharge were greatly higher than those in the control group,which were displayed statistical significance (P＜0.05).Conclusion Community continuity nursing can effectively improve the daily living ability of stroke patients,and enhance the patient′s treatment compliance as well as nursing satisfaction and professional quality of medical staff,which is worthy of clinical application. 2018 Vol. 25 (8): 173-175 [Abstract] ( 180 ) HTML (30 KB)  PDF  (0 KB)  ( 33 ) 176 Application of clinical nursing pathway in patients with lower extremity arteriosclerosis obliterans TANG Jin-hong;LIU Feng-en;LIU Hua-zhi;LIU Jian-ping;DUAN Xun-hong;LIU Xiao-yan Objective To carry out the corresponding clinical nursing pathway for patients with lower extremity arteriosclerosis obliterans treated by different surgical methods,so as to provide reference data for clinical nursing research.Methods Literature review,medical record review and nursing experience were combined to design the clinical nursing pathway and the implementation procedure of lower extremity arteriosclerosis obliterans.80 cases of arteriosclerosis were randomly selected from January 2015 to June 2016 in our department were occlusive disease patients were studied by retrospective analysis method,the design and development of arteriosclerosis obliterans clinical nursing path.Divided into control group and experimental group,40 cases in each group.The control group was used routine nursing plan before the implementation of the path,and the experimental group was adopted the corresponding clinical nursing path according to different surgical methods.The average hospitalization time,rehabilitation time and satisfaction degree of nursing contents and health education among the two groups were used as the basis for evaluating the effect of nursing.Results The total satisfaction degree of nursing and health education in the experimental group was higher than that in the control group(P＜0.05).The average hospitalization time and postoperative rehabilitation time of the experimental group were significantly shorter than that of the control group,the differences were statistically significant(P＜0.05).Conclusion The application of clinical nursing path in patients with occlusion in different surgical treatment of lower extremity arteriosclerosis,can significantly shorten the time in hospital time and rehabilitation of patients after operation,to speed up the bed turnover,improve patient satisfaction with nursing work,promotion and should obtain better economic benefits and social benefits can be used in clinical work. 2018 Vol. 25 (8): 176-178 [Abstract] ( 143 ) HTML (30 KB)  PDF  (0 KB)  ( 34 ) 179 Effect of interventional psychological nursing on treatment compliance and relapse rate in patients with depression CONG Su-lan Objective To investigate the effect of interventional psychological care on the treatment compliance and relapse rate in patients with depression.Methods 80 patients with first-episode depression who were admitted to our hospital from January to December 2014 were randomly selected.They were evenly divided into observation group and control group.After admission,both groups were given conventional antidepressant treatment and nursing.In the observation group,besides the previous treatment,interventional psychological nursing was added.After 3-month intervention,the treatment compliance,the Hamilton depression scale(HAMD)score,and recurrence rate after 2-year follow up visits were compared between the two groups.Results After 3 months of intervention,the compliance of the observation group was better than that of the control group with a statistical difference(P＜0.05).There was no significant difference in HAMD score between the two groups on admission(P＞0.05).After 3-month intervention,the HAMD score of the observation group was significantly lower than that of the control group which differed significantly(P＜0.05).After 2 years of followup,the recurrence rate of the observation group was significantly lower than that of the control group with statistical significance(P＜0.05).Conclusion Application of interventional psychological care such as psychological cognitive therapy,psychoanalytic therapy,health activities support and family psychosocial support in patients with depression can improve the treatment compliance and reduce the HAMD score and the recurrence rate.Interventional psychological care has played a positive role in the treatment and rehabilitation of patients with depression,which is worthy of clinical promotion. 2018 Vol. 25 (8): 179-181 [Abstract] ( 177 ) HTML (28 KB)  PDF  (0 KB)  ( 32 ) 182 Effect of nursing intervention on psychological status of infertile patients FAN Yin-ping Objective To observe the effect of nursing intervention on psychological status of infertility patients.Methods From June 2015 to June 2016,82 infertility patients in our department were treated.They were provided with targeted nursing intervention after psychological status test from July 2016 to September 2017.The psychological status of infertility patients before and after nursing intervention was observed.The improvement of quality of life(QOL)before and after intervention as well as nursing satisfaction were compared in the two groups.Results The scores of self-rating anxiety scale(SAS)and self-rating depression scale(SDS)in patients after intervention were significantly lower than those before intervention with statistical significance(P＜0.05).After intervention,both QOL score and total satisfaction rate of nursing were significantly higher than those before intervention with statistical differences(P＜0.05).Conclusion Most infertility patients have negative psychology such as anxiety and depression in a poor compliance,which affects the successful implementation of related treatment and nursing programs.The implementation of targeted nursing intervention can effectively eliminate or alleviate anxiety and depression in patients,ameliorate psychological status and improve their QOL in a significant effect,which can be applied in clinical practice. 2018 Vol. 25 (8): 182-184 [Abstract] ( 135 ) HTML (29 KB)  PDF  (0 KB)  ( 28 ) 185 Effect of information-motivation-behavior technique model on mental emotions in hemodialysis patients XIE Li-ying;ZHOU Jin-lan;HU Xiao-jiu;ZHAO Chong-ming Objective To study the influence of applying information-motivation-behavioral skills model and focusing solution mode on the psycho-emotional status of hemodialysis patients.Methods From April to December 2017,90 hemodialysis patients in our hospital were enrolled in the study.According to the randomized grouping method,the patients were divided into the skill group,the focus group and the control group,30 cases in each group.The control group was given routine psychological care measures.The skills group added information-motivation-behavioral skills model interventions based on routine nursing measures,Focus group was used on focus on solving the mode of intervention,the use of self-made questionnaires,analysis of patient biochemical changes before and after nursing intervention,as well as changes in patients with psychological and emotional,that is,patient satisfaction.Results Compared with the control group,the indexes of biochemical test results in the two groups of skill group and focus group were better than those of the control group.There was no significant difference between the skill group and the control group before intervention(P＞0.05).After intervention,the difference was statistically significant(P＜0.05).There was no significant difference between before and after intervention in skill group and focus group(P＞0.05).The total satisfaction of patients in control group,skill group and focus group were 76.67%,93.33%and 93.33%,espectively.There was significant difference between control group and skill group (P＜0.05).There was no significant difference between focus group and skill group(P＞0.05).Conclusion The implementation of information-motivation-behavioral skills model interventions and focussolving model interventions can both improve patient outcomes and patient satisfaction and deserve clinical promotion. 2018 Vol. 25 (8): 185-187 [Abstract] ( 164 ) HTML (29 KB)  PDF  (0 KB)  ( 33 ) 188 Effect of predictive care on patients with lumbar disc herniation JIN Lin-ping;CHEN Pei-na;CHEN Yan-jun;LIN Wan-feng;XU Ting Objective To investigate the effect of predictive care on patients with lumbar disc herniation.Methods Clinical data of 50 patients with lumbar disc herniation admitted in our hospital from May to October 2017 were retrospectively analyzed.According to the different nursing measures,20 patients in the control group were provided with routine care and 30 patients in the observation group were supplied with predictive care.The quality of life score,Japanese Orthopedics Association(JOA)score and visual analogue scale(VAS)score of two groups before and after nursing were observed.The rehabilitation effect of the enrolled patients was observed.Results There was no significant difference in quality of life,JOA score or VAS score before nursing in the two groups(P＞0.05).After nursing,the quality of life score and JOA score of patients with lumbar disc herniation were significantly higher than those before nursing.The VAS score was lower than that before nursing.These three indexes in the observation group were all superior to those in the control group.The excellent and good rate of rehabilitation in the observation group was higher than that in the control group with a statistical difference(P＜0.05).Conclusion Predictive care in patients with lumbar disc herniation can improve the quality of life score and JOA score,alleviate pain and enhance the rehabilitation efficiency,which is worthy of clinical application and promotion. 2018 Vol. 25 (8): 188-190 [Abstract] ( 171 ) HTML (27 KB)  PDF  (0 KB)  ( 34 ) 191 Application of comprehensive nursing intervention in patients with hemorrhagic gastric ulcer YAO Juan-juan Objective To explore the application of comprehensive nursing intervention in patients with hemorrhagic gastric ulcer.Methods From July 2016 to July 2017,80 patients with gastric ulcer bleeding in our hospital were selected as the subjects.They were randomly divided into the experimental group and the control group according to the different nursing interventions,40 cases in each group.Two groups of patients were given Omeprazole drug treatment.Among them,the control group was received routine nursing measures.The experimental group was given comprehensive nursing measures on the basis of the control group.The clinical hemostatic effect,hemostasis time,hospitalization time and relapse of two groups of patients with gastric ulcer bleeding were compared.Results The clinical hemostasis of the total efficiency of the experimental group(97.50%)was significantly higher than the control group(77.50%);the experimental group clinical bleeding time(2.3±2.8)d was significantly shorter than that that in the control group(3.1±1.2)d;experimental group hospitalization time(13.1±1.6)d was significantly shorter than that that in the control group(22.5±2.2)d;experimental group clinical disease recurrence rate (5.00%)was significantly lower than that in the control group(22.50%),the clinical total effective rate of hemostasis,hemostasis time,hospitalization time,clinical disease recurrence rate and other aspects of statistical data comparison,there were significant differences(P＜0.05).Conclusion In the clinical treatment of patients with bleeding gastric ulcer in combination with patients,given comprehensive nursing measures can effectively improve clinical efficiency,shorten the clinical bleeding time and hospitalization time of patients,reduce the recurrence rate,worthy of further exploration in clinical research. 2018 Vol. 25 (8): 191-193 [Abstract] ( 161 ) HTML (27 KB)  PDF  (0 KB)  ( 34 ) 194 The effect of complex training nursing intervention in patients with postpartum pelvic floor dysfunction GUO Cui-ying;CHEN Ying;HUANG Lan-bing Objective To explore the clinical effect of rehabilitation training combined with nursing intervention in postpartum pelvic floor dysfunction.Methods 80 patients with postpartum pelvic floor dysfunction admitted to our hospital from November 2016 to November 2017 were enrolled in this study.The patients were divided into two groups based on the time of their visit.Among them,conventional nursing intervention(40 cases)was used in the routine group,the experimental group patients were treated with rehabilitation training(40 cases)on the basis of routine nursing.The pelvic floor muscle strength(Pelvic floor muscle voltage,pelvic floor muscle grading)of the two groups before and after intervention were compared and compared before and after intervention of pelvic floor dysfunction (stress urinary incontinence,pelvic organ prolapsed,Lumbosacral pain)incidence and the patient′s satisfaction with sexual life.Results After intervention,pelvic floor muscle strength and pelvic floor muscle grading of the experimental group were better than that those before the intervention,which were better than that the conventional group(P＜0.05);after the intervention,the experimental group had pelvic floor dysfunction.The incidence was significantly lower than that of the conventional group and the conventional group(P＜0.05).The satisfaction rate of sexual life in the experimental group was 92.50%,which was significantly higher than that of the conventional group(P＜0.05).Conclusion For post-natal pelvic floor dysfunction,the effect of rehabilitation training combined with nursing intervention is significant,which can promote the recovery of pelvic floor function,which is worth recommending. 2018 Vol. 25 (8): 194-196 [Abstract] ( 148 ) HTML (28 KB)  PDF  (0 KB)  ( 35 )

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