单纯依沙吖啶和米非司酮分别配伍米索前列醇、依沙吖啶在中期引产中的效果对比

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Abstract Objective To investigate the clinical efficacy of Ethacridine alone and Mifepristone combined with Misoprostol and Mifepristone combined with Ethacridine in induction of labour in second trimester.Methods The clinical data of 240 pregnant women with gestational age from 14 to 27 weeks who received induction of labor in second trimester in our hospital from February 2001 to December 2016 were retrospectively analyzed.According to the method of induction of labor,the patients were divided into 3 groups,80 cases in each group.The control group was given Ethacridine for labor induction,study group 1 was given Mifepristone combined with Misoprostol for induction of labor,and study group 2 was given Mifepristone combined with Ethacridine for induction of labor.The induction of labor,duration of labor induction,total labor time,volume of blood loss and placental residue were compared between the three groups of puerpera.Results The successful rate of induction of labor in the study group 1 and the study group 2 was significantly higher than that in the control group(P＜0.05).The duration of labor induction and total labor time in study group 1 and study group 2 were significantly shorter than those in the control group(P＜0.05).The proportion of the volume of blood loss＞150 ml in study group 2 and control group was significantly lower than that in study group 1(P＜0.05).The proportion of placental residue in study group 2 was significantly lower than that in control group and study group 1(P＜0.05).Conclusion Compared with Ethacridine alone,the duration of labor induction of Mifepristone combined with Misoprostol and Mifepristone combined with Ethacridine is short,with a high successful rate of induction of labor.Compared with Ethacridine alone and Mifepristone combined with Misoprostol,Mifepristone combined with Ethacridine has a higher safety.

Key words： Ethacridine Mifepristone Misoprostol Pregnancy in the second trimester Induction of labour

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	LI Zhong-hui
	LIU Jiang-mei
	LAI Zhu-yuan

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LI Zhong-hui,LIU Jiang-mei,LAI Zhu-yuan. Comparison of the efficacy between Ethacridine alone and Mifepristone combined with Misoprostol and Mifepristone combined with Ethacridine in induction of labour in second trimester[J]. 中国当代医药, 2018, 25(8): 74-76.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I8/74

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