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Quick Search     Adv Search 2016 Vol. 23, No. 27 Published: 2016-09-28   4 Study on extraction technology of Motherwort alkaloids by orthogonal test WANG Jing-yi;GAO Jie Objective To select the optimum extraction technology of Motherwort alkaloids.Methods L9（34）orthogonal test was used.The total alkaloids was dectected as the criterion to investigate the effect of acid concentration，ethanol concentration，extraction time and extraction times on total alkaloids in cold-dipping extraction.Results The optimum extraction technologywas 70%ethanol concentration，extracted two times，40minutes each time，dissolved with 0.10mol/L Hydrochloric acid.Conclusion The optimum method is Simple，economical and feasible. 2016 Vol. 23 (27): 4-6 [Abstract] ( 158 ) HTML (42 KB)  PDF  (0 KB)  ( 25 ) 7 Study on microscopic identification of root,stem and leaf of Datura Stra-monium GONG Li-min;ZHOU Ying;PAN Qing-ping;LIU Ta-si ;XIAO Bing-mei Objective To study themicroscopic identification features of root，stem and leaf of Datura stramonium so as to provide the basis for further improvement of themorphology and identification of Datura stramonium and expansion ofmedical resources.Methods The microscopic identification of the cross section and powder characteristics of root，stem and leaf of Datura stramonium were made　（hand sectioning method，leaf epidermis tearing method and powder production method）.Results The transverse section of root had collateral vascular bundles and formed an obvious layer ring；in the cross section of the stem，vascular bundles were radially arranged with polygonal wood fiber and cavitary pith；in the cross section of the leaf，many visible crystals were seen in new leaves and lots of columnar crystals were seen in the old leaves.The calcium oxalate crystals，murus，wood fiber and cork cells could be found in root powder；the small calcium oxalate crystals，bordered pit，glandular hairs and non-glandular hairs could be seen in stem powder；the calcium oxalate crystals，column crystals，thread tube，glandular hairs，non-glandular hairs，anisocytic type stoma could be found in leaf powder.Themicroscopic constant of leaf included，the average stomatal length was 21.34μm，the average width was 16.20μm，the average pore density of 176.8/mm2，palisade ratio was 1.4，vein islet number was 20.3/mm2. Conclusion Themicroscopic identification ofmedicinal characteristics of Datura stramonium provides reference for criteria formulation of themicroscopic identification of Datura stramonium. 2016 Vol. 23 (27): 7-10转4 [Abstract] ( 171 ) HTML (44 KB)  PDF  (0 KB)  ( 39 ) 11 Detection and genetic therapy significance of PTEN,p14ARFand Survivin in lung carcinoma REN Li-juan;LIU Ya-li;HOU Mei-feng;DING Yan-long Objective To study the expression and the relationship of PTEN，p14ARFand Survivin in lung carcinoma and offer more scientific theoretic basis for treatment and diagnosis of lung carcinoma.Methods 87 cases of primary bronchogenic carcinoma tissues and 13 cases normal lung tissues in our hospital from January 2009 to December 2015 were detected by SP immunohistochemical method，and their expression and correlation were studied.Results The positive expression of PTEN，p14ARFwere higher in normal lung tissue than primary bronchogenic carcinoma，the expression of Survivin was in contrast.The expression of PTEN，p14ARFwere reduced with poorly，moderately and welldifferentiated group，by contrast，the expression of Survivin was increasing（P＜0.01）.The expression of PTEN，p14ARFwere reduced，while the expression of Survivin was increasing with clinical stages enlarging in clinical stages group，PTEN，p14ARFand Survivin among stageⅠ，Ⅱ，Ⅲ，Ⅳhad statistical difference（P＜0.01）.Among PTEN，p14ARFand Survivin were correlatively analyzed in lung carcinoma.There is a positive correlation between PTEN and p14ARF（r=0.6489，P＜0.01），with negative correlation between Survivin and PTEN（r=-0.5743，P＜0.01）or Survivin and p14ARF（r=-0.6860，P＜0.01）.The three gene are associated with the primary bronchogenic carcinoma.Conclusion PTEN，p14ARF，Survivin play a combined role in the apoptosis and proliferation of primary bronchogenic carcinoma.It is important to improve our treatment and diagnosis of primary bronchogenic carcinoma. 2016 Vol. 23 (27): 11-14 [Abstract] ( 153 ) HTML (45 KB)  PDF  (0 KB)  ( 38 ) 15 Im pact of different treatment factors on expression of vascular endothelial grow th factor in primary cultured human bronchial epithelial cells in-fected with respiratory virus GAO Yuan-mei;XU Zhong;HUANG Dong-jian;CAIShao-xi Objective To explore the impact of different treatment factors on expression of vascular endothelial growth factor（VEGF）in primary cultured nornal human bronchial epithelial cells（NHBE）infected with respiratory syncytial virus（RSV）.Methods The impact of different treatment factors on expression NHBE VEGF infected with RSV was tested by using fluorescence quantitative PCR and ELISA.Results After NHBE infected with RSV，the expression of NHBE VEGFwas significantly increased，and with obvious time dependence and concentration dependence，Dexamethasone could significantly inhibit expression of VEGF in NHBE infected with RSV，and the difference was statistically significant compared with RSV infection group　（P＜0.05）.25 hydroxy vitamin D3alone using could stimulate that NHBE expressed VEGF，but it could inhibit that NHBE infected with RSV expressed VEGF，and the difference was statistically significant compared with RSV infection group　（P＜0.05）.Conclusion RSV increases the expression of VEGF in bronchial epithelium，while Dexamethasone and 25 hydroxy vitamin D3can reduce this effect. 2016 Vol. 23 (27): 15-18 [Abstract] ( 139 ) HTML (46 KB)  PDF  (0 KB)  ( 42 ) 19 Effect observation of m inimally invasive funnel chest orthopedics in the treatment of funnel chest LIZhi-yong;GONG Jun;ZENG Qing-wu;LIU Jun Objective To explore the effect ofminimally invasive funnel chest orthopedics in the treatment of funnel chest.Methods 75 cases of congenital funnel chest in our hospital from January 2010 to December 2015 were selected and divided into the control group（45 cases）and the observation group（30 cases）according to the different operation method.The control group was treated with traditional surgical treatment，the observation group was treated with minimally invasive funnel chest orthopedics.The operation conditions（operation time，intraoperative blood loss，hospitalization days），the improvement situation of cardiac and pulmonary function　（FEV1，MVV，cardiac index and left ventricular ejection fraction，stroke volume and cardiac output）before and after surgery in the two groups was compared.Results The operation time and postoperative hospital stay in the observation group was shorter than that in the control group，the amount of bleeding in the observation group was less than that in the control group，the degree of postoperative pain in the observation group was lower than that in the control group，with significant difference（P＜0.05）.The cardiac and pulmonary function indexes of the two groups after operation was better than that before operation，with significant difference　（P＜0.05）.There was no significant difference in the cardiac and pulmonary function indexes after operation between the two groups（P＞0.05）.Conclusion The correction effect ofminimally invasive funnel chest orthopedics is good，with less trauma，less bleeding，shorter operation time，and postoperative recovery of patients is fast，it isworthy of clinical promotion and application. 2016 Vol. 23 (27): 19-21 [Abstract] ( 125 ) HTML (37 KB)  PDF  (0 KB)  ( 37 ) 22 Clinical app lication of single port laparoscopic technique ZHENG Bao-e;TONG Jian-hua;ZHOU Jun;CHEN Jiang-bo Objective To explore the application effect of single port laparoscopic technique.Methods 100 cases of gallbladder disease in our hospital from July 2007 to June 2013 were selected and divided into the observation group and the control group according to the different treatmentmethods，50 cases in each group.The observation group was given single port laparoscopic technique treatment，and the control group was given conventional laparoscopic technique treatment.The operative time，gastrointestinal ventilation time，intraoperative blood loss，hospital stay，the incidence rate of complications and pain score in the two groupswas compared.Results There was no significant difference in the operative time between the two groups　（P＞0.05）.The amount of intraoperative blood loss in the observation group was less than that in the control group，the time of gastrointestinal ventilation and hospital stay in the observation group was shorter than that in the control group，with significant difference（P＜0.05）.Therewas no significant difference in the incidence rate of complications between the two groups（P＞0.05）.The postoperative pain score of the observation group was （1.8±0.7）points，which was lower than（3.4±1.1）points of the control group，with significant difference（P＜0.05）.Conclusion The single port laparoscopic technique can shorten the hospital stay，better promote the patient＇s postoperative recovery，it isworthy of clinical promotion and application. 2016 Vol. 23 (27): 22-24 [Abstract] ( 133 ) HTML (37 KB)  PDF  (0 KB)  ( 26 ) 25 Exp loration of the clinical effect of app lication of small incision appendectomy for appendicitis in elderly patients ZHOU Wei Objective To explore the clinical effect of small incision appendectomy in the treatment of elderly patients with appendicitis.Methods 78 elderly patients with appendicitis in our hospital from September 2015 to April 2016 were selected and divided into the control group and the experiment group according to the draw method，39 cases in each group.The control group was treated with traditional surgery，the experiment group was treated with small incision appendectomy.The treatment effect between the two groups was compared.Results The operation time and incision length of the experimental group was shorter than that of the control group，the amount of bleeding in the experimental group was less than that in the control group，with significant difference（P＜0.05）.The rate ofwound infection in the experimental group was 5.13%，which was lower than 17.95%in the control group，with significant difference（P＜0.05）.The recovery time of the experimental group was（4.17±1.03）days，which was shorter than　（7.74±1.23）days of the control group，with significant difference　（P＜0.05）.Conclusion Small incision appendectomy can shorten the operation time and recovery time of elderly patientswith appendicitis，reduce the amount of bleeding，shorten the length of incision and improve the safety of operation，it isworthy of clinical promotion and application. 2016 Vol. 23 (27): 25-27 [Abstract] ( 142 ) HTML (38 KB)  PDF  (0 KB)  ( 33 ) 28 App lication of quality control circle management in enhancing the satisfaction degree of doctors to intestinal cleaning degree of patients QIN Xi-xiang;PENG Tie-li;ZHANG Han-xian;SU Kai-hua;LIU Jun-ying Objective To explore the application effects of quality control circlemanagement in enhancing the satisfaction degree of doctors to intestinal cleaning degree of patients.Methods 100 patients accepted colonoscopy examination in the department of digestivemedicine in our hospital from July in 2014 were selected as the control group according to convenience sampling method，100 patients accepted colonoscopy examination in the department of digestive medicine in our hospital from December in 2014 were selected as the observation group.The observation group was given quality control circlemanagement，the control group was not given quality control circlemanagement.The satisfaction degree of doctors to intestinal cleaning degree of patients and related indicators in the two groups was compared.Results The satisfaction degree of doctors to intestinal cleaning degree of patients in the observation group was 93%，which was higher than 75%in the control group，with significant difference　（P＜0.05）.The application ability of quality control circle，team spirit，professional knowledge，communication and coordination ability，activity confidence and responsibility honor score in the observation group was higher than that in the control group，with significant difference　（P＜0.05）. Conclusion Carrying out quality control circle activity is beneficial to improve the intestinal cleanliness of patients and which can also promotes the ability of circlemember＇s knowledge and application of quality control circle at the same time. 2016 Vol. 23 (27): 28-30 [Abstract] ( 133 ) HTML (41 KB)  PDF  (0 KB)  ( 27 ) 31 Clinical analysis of glucocorticoid combined with Terbutaline in the treatment of acute exacerbation of chronic obstructive pulmonary disease ZOU Xiao-xin;LIU Yun-yun;LING Xue-feng Objective To explore the clinical effect of glucocorticoids combined with Terbutaline in the treatment of acute exacerbation of chronic obstructive pulmonary disease　（COPD）.Methods 48 cases of COPD in our hospital from June 2013 to June 2015 were selected and divided into the experimental group and the control group according to the different treatment methods，24 cases in each group.The control group was treated with Terbutaline，the experimental group was treated with glucocorticoids on the basis of the control group.The treatment effect，oxygen partial pressure （PaO2），carbon dioxide partial pressure　（PaCO2）and the incidence rate of adverse reaction was compared between the two groups.Results The total effective rate of the experimental group was 96%，which was higher than 70%of the control group，with significant difference　（P＜0.05）.The level of PaO2in the experimental group after treatmentwas higher than that in the control group，the level of PaCO2in the experimental group after treatment was lower than that of the control group，with significant difference（P＜0.05）.The incidence rate of adverse reactions in the experimental group was 4.2%，which was lower than 25.0%in the control group，with significant difference　（P＜0.05）.Conclusion Clinical effect of glucocorticoid combined with Terbutaline in the treatment of acute exacerbation of COPD is better，which can not only improve the level of PaO2and PaCO2，reduce the incidence rate of adverse reaction，but also can improve the quality of life of patients，it isworthy of clinical promotion and application. 2016 Vol. 23 (27): 31-33 [Abstract] ( 131 ) HTML (39 KB)  PDF  (0 KB)  ( 29 ) 34 Effect observation of Immune Three Oxygen combined with Kangfuxin Liquid retention enema in the treatment of radiation proctitis HUANG Shu-mei;WANG Jing;ZOU Shu-qing;LIU Ye-qing;ZHANG Xiao-chun Objective To explore the effect of Immune Three Oxygen combined with Kangfuxin Liquid retention enema in the treatment of radiation proctitis.Methods 100 cases of radiation proctitis after radiotherapy of cervical cancer from June 2012 to June 2015 in our hospitalwere selected and divided into the observation group and the control group according to the order of admission，50 cases in each group.The control group was treated with conventional Kangfuxin Liquid retention enema，the observation group was treated with Immune Three Oxygen combined with Kangfuxin Liquid retention enema.The curative effect and the recurrence rate in the two groupswas compared.Results The total effective rate of the observation group was 98%，which was higher than 86%of the control group，with significant difference　（P= 0.0270）.The total recurrence rate of the observation group was 2%，which was lower than 48%of the control group，with significant difference（P＜0.01）.Conclusion Immune Three Oxygen combined with Kangfuxin Liquid retention enema can effectively improve the treatment effect of radiation proctitis patients，reduce the recurrence rate，it is worthy of clinical promotion and application. 2016 Vol. 23 (27): 34-36 [Abstract] ( 162 ) HTML (38 KB)  PDF  (0 KB)  ( 42 ) 37 Efficacy and safety of gastric fundus tissue adhesive injection under endoscopy combined with variceal ligation in the treatment of esophageal and gastric variceswith cirrhosis LIJie;FANMing-juan;GU Jin-lian;ZHANG Long Objective To explore the effect and safety of gastric fundus tissue adhesive injection under endoscopy combined with variceal ligation in the treatment of esophageal and gastric varices（EGV）with cirrhosis.Methods 90 cases of EGV with cirrhosis in our hospital from January 2010 to January 2013 were selected and randomly divided into the experiment group and the control group，45 cases in each group.The control group was given variceal ligation，and the experiment group was given gastric fundus tissue adhesive injection under endoscopy combined with variceal ligation. The re-bleeding rate，the disappearing rate of varices and the incidence rate of adverse reaction in the two groups was compared.Results The re-bleeding rate of the experimental group was 20.0%，which was lower than 40.0%of the control group，with significant difference　（P＜0.05）.The disappearing rate of varices in the experimental group was 40.0%，which was lower than 8.9%in the control group，with significant difference（P＜0.01）.The incidence rate of adverse reaction in the experimental group was 31.1%，which was lower than 46.7%in the control group，with significant difference （P＜0.01）.Conclusion Gastric fundus tissue adhesive injection under endoscopy combined with variceal ligation in the treatment of EGV with cirrhosis has significant curative effects，with low relapse rate and high safety. 2016 Vol. 23 (27): 37-39 [Abstract] ( 158 ) HTML (37 KB)  PDF  (0 KB)  ( 29 ) 40 Effect analysis of laparoscopic splenectom y in the treatment of idiopathic thrombocytopenic purpura YIBo;CHEN Xun;TANG Cai-xi Objective To explore the effect of laparoscopic splenectomy in the treatment of idiopathic thrombocytopenic purpura.Methods 40 patientswith idiopathic thrombocytopenic purpura from January 2010 to January 2015 in our hospitalwere selected and randomly divided into the trial group and the control group，20 cases in each group.The control group was treated with traditional splenectomy，the trial group was treated with laparoscopic splenectomy.The therapeutic effect，the amount of intraoperative blood loss，operative time，length of hospital stay，recurrence rate and the incidence rate of complication in the two groups was compared.Results There was no significant difference in the total effective rate between the two groups（P＞0.05）.The amount of intraoperative blood loss in the trial group was less than that in the control group，the length of hospital stay in the trial group was shorter than that in the control group，the total amount of fluid infusion and the total hospital costs in the trial group was less than that in the control group，with significant difference（P＜0.05）.There was no significant difference in the operative time between the two groups（P＞0.05）.There was no significant difference in the recurrence rate between the two groups（P＞0.05）.The incidence rate of complication in the trial group was 15.0%，which was lower than 40.0%in the control group，with significant difference（P＜0.05）.Conclusion Laparoscopic splenectomy in the treatment of idiopathic thrombocytopenic purpura can effectively improve the patient＇s symptoms，operation is safe，with low recurrence rate，fewer complications，it has important clinical significance. 2016 Vol. 23 (27): 40-42转64 [Abstract] ( 161 ) HTML (41 KB)  PDF  (0 KB)  ( 35 ) 43 Related of chronic heart failure in sinus rhythm and shock WANG Zhang-bo Objective To explore on the correlation between chronic heart failure in sinus rhythm and shock.Methods 126 patients were obtained a clear diagnosis of chronic heart failure in elderly and selected from June 2013 to June 2015 in our hospital as object in this study，which was based on the value in accordance with the initial shock rhythm，turbulence slope，patients into the low risk group and high risk group，same period 126 cases of healthy people were selected as a control group.All subjects were expanded biochemical tests，holter monitoring，echocardiography，6 min walk test value check，QRSD measurement，and follow-up.All subjects of the test results for statistical was analysised，looking for chronic heart failure and sinus rhythm correlated shocks.Results Statistics found that chronic heart failure patients and the control group indexes HRT test results were demonstrated that chronic heart failure the initial shock value of brain natriuretic peptide，left ventricular end-diastolic dimension，QRSD other indicators of the level of detection were higher than that of control group（P＜0.05），but turbulence slope，standard normal sinus rhythm RR interval difference，left ventricular ejection fraction，6 min walk test value were lower than that of control group　（P＜0.05），in addition，a heart failure patients，the high-risk group and low risk group indexes HRT test results，there were significant differences（P＜0.05）；follow-up period，compared to the situation in high-risk group and low risk group of cardiovascular events in patients with chronic heart failure，showed that high-risk group the incidence of cardiovascular events was significantly higher than that of low risk group　（P＜0.05），in addition，a cardiogenic shock，the incidence ofmalignant arrhythmias in high-risk group were lower than that of risk group　（P＜0.05）.Conclusion The observed between chronic heart failure in sinus rhythm and shock there is an obvious correlation can be used as shock sinus rhythm in patients with chronic heart failure is an important clinical parameters，but also as an important prognostic index，the clinical value of significant concern. 2016 Vol. 23 (27): 43-45 [Abstract] ( 124 ) HTML (38 KB)  PDF  (0 KB)  ( 35 ) 46 The research of the relevance between pentraxin 3（PTX 3）and coronary heart disease XIE Guo-bo;XIONG Li;YANG Ming;SHENG Guo-tai;YU Mao-sheng;CAO Qian-qiang;ZHANG Fan-zhi;LIYu;SUN Han-jun Objective To explore the relevance between pentraxin 3（PTX3）and the occurrence and development of coronary heart disease.Methods 60 cases of coronary heart disease　（CHD）from July 2013 to December 2014 in our hospitalwere selected as the CHD groups.There were 20 cases in acutemyocardial infarction（AMI）group，stable angina pectoris（SAP）group and unstable angina pectoris（UAP）respectively，20 cases of healthy persons were selected as the control group.Compared hs-CRP，PTX3 levels and Genisin scores between the four groups，and carried out the risk factors for the recent prognosis of CHD by logistic regression analysis.Results In hs-CRP，PTX3，and Genisin score，the scores of CHD group were significantly higher than those of control group，and there were significant differences between groups（P＜0.05）.UAP group and AMIgroup compared with SAP group，the differences between groupswere statistically significant（P＜0.05）.In hs-CRP and PTX3，the differences between the AMIgroup and the UAP group were not statistically significant（P＞0.05），and the differenceswere statistically significant between the two groups in the Genisin score（P＜0.05）.LDL-C，hs-CRP and PTX3 made the influence factors of the recent prognosis of CHD.Conclusion The level of PTX in patientswith acute coronary syndrome were significantly increased，which can be used as the early diagnosis of acute coronary syndromeclinical indicators，can play a positive role in the assessment of prognosis in CHD patients. 2016 Vol. 23 (27): 46-48 [Abstract] ( 152 ) HTML (38 KB)  PDF  (0 KB)  ( 45 ) 49 Factor analysis of stone transferring and countermeasures in laparoscopic ureterolithotom y ZHONG Xin;LIZheng-zhong;XIE Fang-lin;ZHONG En-peng Objective To explore the factors of stone transferring and countermeasures in laparoscopic ureterolithotomy. Methods 403 patients with stones in the upper and middle parts of the ureter in our hospital from January 2006 to June 2016 were selected as research objects，their clinical data were retrospectively analyzed.The influence factors of stone transferring during laparoscopic operation in the patients with ureteral calculi were summarized.Results In 403 patientswith stones in the upper and middle parts of the ureter，there were 22 patients occurred with stone transferring. The stone diameter，degree of hydronephrosis，rough operation of ureter dissection，and whether or not to take corresponding precautionarymeasures after exposure of ureter located with the stoneswere risk influence factors of stone transferring in laparoscopic ureterolithotomy.Conclusion There are many factors of stone transferring in laparoscopic ureterolithotomy including the stone diameter，degree of hydronephrosis，rough operation of ureter dissection，and whether or not to take corresponding precautionarymeasures after exposure of ureter located with the stones.In clinic，precaution should be strengthened on these influence factors aiming at reducing the occurrence of stone transferring during surgery and increasing operative success rate. 2016 Vol. 23 (27): 49-51 [Abstract] ( 135 ) HTML (35 KB)  PDF  (0 KB)  ( 34 ) 52 Effects observation of high flux hemedialysis and hemoperfusion com-bined with hemodialysis in the treatment of patients with end-stage dia-betic nephropathy CHEN Kai-jun;YEWen-jie;WANG Huan Objective To compare effects of high flux hemedialysis　（HFHD）and hemoperfusion combined with hemodialysis（HP+HD）in the treatment of end-stage diabetic nephropathy.Methods 86 cases of patients with endstage diabetic nephropathy from May 2011 to April 2015 in our hospital were selected and randomly divided into the research group and the control group，43 cases in each group.The control group was treated with HFHD，the research group was treated with HP+HD.The improvement situation of nutrition indicators，micro-inflammation state and blood lipid in the two groups was compared.Results The levels of red blood cells（RBC），hemoglobin　（HGB），serum albumin （Alb），vitamin B12and folic acid after treatment of 6months in the two groupswas higher than that before treatment，with significant difference　（P＜0.05）.The level of RBC and HGB in the research group after treatment of 6monthswas lower than that in the control group after treatment of 6 months，the levels of Alb，vitamin B12and folic acid in the research group after treatment of 6 monthswas higher than that in the control group after treatment of 6 months，with significant difference（P＜0.05）.The levels of high sensitive C reactive protein（hs-CRP），β2microglobulin（β2-MG）and interleukin-6 （IL-6）after treatment of 6months in the two groupswas lower than that before treatment，with significant difference（P＜0.05）.The level of hs-CRP，β2-MG and IL-6 in the research group after treatment of 6 months was lower than that in the control group after treatment of 6 months，with significant difference　（P＜0.05）.The levels of total cholesterol（TC），triglyceride　（TG），low density lipoprotein cholesterol（LDL-C）after treatment of 6 months in the two groupswas lower than thatbefore treatment，the levels of high density lipoprotein cholesterol（HDL-C）after treatment of 6months in the two groupswas higher than that before treatment，with significant difference　（P＜0.05）.The level of TC，TG，LDL-C in the research group after treatment of 6monthswas lower than that in the control group after treatment of 6 months，the levels of HDL-C in the research group after treatment of 6 months was higher than that in the control group after treatment of 6 months，with significant difference　（P＜0.05）.Conclusion HFHD and HP+HD are both effective for patients with end-stage diabetic nephropathy，each have advantages and disadvantages.In clinical practice，the treatment should be selected according to the specific circumstances. 2016 Vol. 23 (27): 52-54转57 [Abstract] ( 164 ) HTML (42 KB)  PDF  (0 KB)  ( 34 ) 55 Clinical effect and com p liance observation of transurethral resection of bladder tumor in the treatment of superficial bladder tumor WANG Yang Objective To explore the clinical effect and compliance of transurethral resection of bladder tumor in the treatment of superficial bladder tumor.Methods 70 patientswith superficial bladder tumor in our hospital from January 2010 to January 2015 were selected and divided into the study group and the control group according to different therapies，35 cases in each group.The study group was given the transurethral resection of bladder tumor，the control group was given the conventional open operation.The operation time，the amount of bleeding during operation，intubation time，hospitalization time，the incidence rate of complication，the recurrence rate and treatment compliance in the two groups was compared.Results The operation time，intubation time，postoperative hospitalization time in the study group was shorter than that in the control group，the amount of bleeding during operation in the study group was less than that in the control group，with significant difference　（P＜0.05）.There was no significant difference in the incidence rate of complication such as obturator nerve reflex，bladder perforation，massive hemorrhage and the recurrence rate between the two groups　（P＞0.05）.The compliance rate of the study group was 97.14%，which was higher than 85.71%of the control group，with significant difference（P＜0.05）.Conclusion The transurethral resection of bladder tumor has a better effect in patientswith superficial bladder tumor，which can minimize the operation wound，promote the patient＇s fast recovery，improve the treatment compliance and reduce the incidence rate of complication. 2016 Vol. 23 (27): 55-57 [Abstract] ( 150 ) HTML (35 KB)  PDF  (0 KB)  ( 33 ) 58 Clinical study of relevant factors of urinary tract infection in elderly fe-male inpatients ZHANG Jin;XIAO Yun-wei;CAO Xia Objective To explore the relevant factors of urinary tract infection（UTI）in elderly female inpatients. Methods Clinical data from 80 elderly female inpatients with UTI from March 2014 to March 2015 in our hospital were retrospectively analyzed.Relevant clinical factor was analyzed.Results Advanced age，long time of catheter indwelling，and invasive performancewere risk factors triggering female UTI.Conclusion Effectivemeasures like reduction of invasive performance and strict sterilization can reduce the incidence rate of UTI in female inpatients. 2016 Vol. 23 (27): 58-60 [Abstract] ( 144 ) HTML (38 KB)  PDF  (0 KB)  ( 33 ) 61 Clinical research of Calcitriol combined with Pancreatic Excitation Pep-tide Enzyme in the treatment of early diabetic nephropathy TAN Fei;HE Yong Objective To explore the clinical effect of Calcitriol combined with Pancreatic Excitation Peptide Enzyme in the treatment of early diabetic nephropathy.Methods 79 patients with early diabetic nephropath from August 2012 to December 2015 in our hospitalwere selected and divided into the control group（40 cases）and the treatment group（39 cases）according to the random number tablemethod.The control group was treated with Pancreatic Excitation Peptide Enzyme on the basis of routine treatment，the treatment group was treated with Calcitriol on the basis of the control group.The improvement situation of serum creatinine（Scr），urinary protein excretion rate（UAER），24 h urine protein，high sensitivity C reactive protein　（hs-CRP）and other indicators in the two groupswas recorded，the improvement situation of hemorheology indicators such as the plasma viscosity and blood viscosity（low and high）in the two groupswas compared.Results The level of plasma viscosity and blood viscosity after treatment in the two groups was lower than that before treatment，with significant difference（P＜0.05）.The level of plasma viscosity and blood viscosity after treatment in the treatment group was lower than that in the control group after treatment，with significant difference（P＜0.05）.The levels of hs-CRP，UAER，24 h urinary protein after treatment in the two groups was lower than that before treatment，with significant difference　（P＜0.05）.The level of hs-CRP，UAER，24 h urinary protein after treatment in the treatment group was lower than that in the control group after treatment，with significant difference　（P＜0.05）.The total effective rate of the treatment group was 79.74%，which higher than 67.50%of the control group，with significant difference　（P＜0.05）. Conclusion Curative effect of Calcitriol combined with Pancreatic Excitation Peptide Enzyme in the treatment of early diabetic nephropathy is distinct，which can reduce the urine protein better as well as inhibit inflammatory reaction，it is worthy of clinical promotion and application. 2016 Vol. 23 (27): 61-64 [Abstract] ( 155 ) HTML (42 KB)  PDF  (0 KB)  ( 40 ) 65 Influence　of quantitative　sensory　testing　of hemodiafiltration　and hemodialysis combined with hemoperfusion in the treatment of urem ic patientswith peripheral neuropathy XU Bing-xia;ZHANG Yun-xia;CHEN Xue-xun;WUWen-bin Objective To explore the influence of hemodiafiltration（HDF），hemodialysis（HD）combined with hemoperfusion（HP）on the threshold of quantitative sensory testing（QST）in uremic patientswith peripheral neuropathy，to evaluate the effect of HDF，HD+HP in the treatment of uremic peripheral neuropathy.Methods 52 uremic patients with peripheral neuropathy in our hospital from January 2013 to October 2015 were selected and randomly divided into the HDF group and the HD+HP group，26 cases in each group.The HDF group was given regular HD 2 times a week and HDF once a week，the HD+HP group was given regular HD 2 times a week and HD+HP once a week.The clinical symptoms of peripheral neuropathy in the two groups before and after treatment for 4monthswas observed respectively，the QST temperature threshold and vibration perception threshold of 4 different parts such as the left finger，hypothenar，leg and foot in the two groupswas compared.Results The clinical symptoms of peripheral neuropathy，the QST temperature threshold and vibration perception threshold of 4 different parts after treatment for 4months in the two groupswas better than that before treatment，with significant difference（P＜0.05）.The improvement degree of temperature threshold after treatment in the HD+HP group was better than that in the HDF group，with significant difference（P＜0.05）.Conclu-sion HD+HP，HDF can effectively improve peripheral neuropathy of uremic patients. 2016 Vol. 23 (27): 65-68 [Abstract] ( 135 ) HTML (41 KB)  PDF  (0 KB)  ( 42 ) 69 Risk assessment of placenta im p lantation in patientswith p lacenta previa LIANGMei-zhen;WEIFu-bing;TANG Li;ZHONG Wen-bin;WEN Si-min;WANG Miao-na Objective To establish a risk assessment table for placenta implantation in patientswith placenta previa，and to evaluate the forecasting efficiency of this risk assessment table.Methods Data of 955 patientswith placenta previa in 9 hospitals in Dongguan City included Maternal and Child Health Care Hospital of Dongguan City from January 2011 to December 2013 were retrospectively analyzed，patients with placenta previa and placenta implantation were selected as case group and patients with simple placenta previa but not combined with placenta implantation were selected as control group.550 caseswere selected to analyze the independent risk factors of placenta previa and placenta implantation.The high risk factors and color Doppler ultrasound results of placenta previa and placenta implantation were given the value and risk assessment table of placenta previa and placenta implantation was established.Data of 405 patients with placenta previa were selected to evaluate the forecasting efficiency of this risk assessment table.Results History of cesarean section（OR=2.059，95%CI：1.289-3.289），number of pregnant（OR=1.821，95%CI：1.179-2.814），number of give birth（OR=1.577，95%CI：1.336-1.765）and central type placenta（OR=1.971，95%CI：1.534-2.534）were the independent risk factors of placenta previa and placenta implantation.There was no statistical difference between the risk degree and the actual incidence of placenta previa patients with placenta implantation　（χ2=8.127，P=0.491）.Conclusion Risk assessment of placenta previa combined with placenta implantation is advantageous to the risk management of patients with placenta previa and the established evaluation table can predict the risk of placenta implantation in patients with placenta previa.Due to non large sample and multi center study，the data need to be further collected to analyze and study to establish amore reliable evaluation system. 2016 Vol. 23 (27): 69-71 [Abstract] ( 147 ) HTML (38 KB)  PDF  (0 KB)  ( 30 ) 72 Observation of early diagnosis index value and the clinical therapeutic effect of rheumatoid arthritis SHAO Li Objective To discuss the early diagnosis index of rheumatoid arthritis and clinical therapeutic effect. Methods From August 2013 to February 2016，38 cases of children with rheumatoid arthritis in the hospital were selected as observation group　（who were divided into observation groupⅠand observation groupⅡ，with 19 cases in each group，at the same time patients in the observe groupⅠ group were given western medicine treatment，while patients in the observation groupⅡwere given combined therapy of Chinese and Western medicine），the other 38 cases of connective tissue disease in children with non rheumatoid arthritis were as control group by stratified block randomized groupingmethod.Rheumatoid factor，cyclic citrullinated peptide，antinuclear antibodies，anti Sm antibody，anti RNP antibody，anti double stranded DNA antibody levels and its specificity，sensitivity were observed and compared between the observation group and the control group，and effect between the observation groupⅠand the observation groupⅡwere compared.Results In the observation group positive rate of rheumatoid factor，cyclic citrullinated peptide，antinuclear antibodies，anti Sm antibody，anti RNP antibody，anti double stranded DNA antibody were higher than those in the control group　（P＜0.05）；sensitivity of cyclic citrullinated peptide was lower than that of rheumatoid factor，antinuclear antibodies，anti Sm antibody，anti RNP antibody and anti double stranded DNA antibody，while specificity of anti Sm antibody，anti double stranded DNA antibody was higher than that of rheumatoid factor，cyclic citrullinated peptide，antinuclear antibodies，anti RNP antibody　（P＜0.05）；total effective rate in observation groupⅡwas higher than that in the observation groupⅠ （P＜0.05）.Conclusion Autoantibodies detection can be used as one of the effective screening index of early diagnosis of children with rheumatoid arthritis，seize the window period and effective treatment can improve the clinical curative effect. 2016 Vol. 23 (27): 72-75 [Abstract] ( 150 ) HTML (46 KB)  PDF  (0 KB)  ( 38 ) 76 Effect of nipp le care in reducing the incidence of postpartum mastitis of pregnantwomen LIU Gui-ying;XIAN Hai-yan;LING Qing-xia Objective To investigate effects of nipple care in reducing the incidence of postpartum mastitis of pregnant women.Methods 150 cases of pregnantwomen in department of gynecology and obstetrics of our hospital from January to June 2015 were randomly divided into research group and control group，each group was 75 cases.Patients in the research group were treated with routine prenatal nipple care，while no treatment was given in the control group.Occurrence of postpartum cracked nipple and mastitis，success rates of breastfeeding and breastfeeding at different periods of two groups were compared.Results There were 4.0%of postpartum cracked nipple and 6.7%ofmilk deposition in the research group，which were lower than 14.7%，18.7%in the control group　（P＜0.05）.Occurrence ofmastitiswas 1.3%in the research group，which was lower than 12.0%in the control group（P＜0.05）.Breastfeeding success rate of the research group was higher than that of the control group（P＜0.05）.Before discharge and postnatal 4months and 6months，thematernal exclusive breastfeeding rate of the research group was higher than that of the control group，mixed feeding rate and artificial feeding ratewere lower（P＜0.05）.Conclusion Prenatal nipple care can effectively reduce the incidence of postpartum mastitis，improve breastfeeding and mother-baby health，it isworthy of clinical promotion. 2016 Vol. 23 (27): 76-78 [Abstract] ( 127 ) HTML (34 KB)  PDF  (0 KB)  ( 27 ) 79 Effect analysis of immediately p lacing MYCu intrauterine device after abortion under B ultrasound monitoring ZHONG Yuan-mei Objective To analyse effect analysis of immediately placing MYCu intrauterine device　（IUD）after abortion under B ultrasound monitoring.Methods 130 women of received induced abortion in our hospital from January 2014 to March 2015 were selected as study object and randomly divided into obsevation group and control group according to different devices used，each group of 65 cases，MYCu IUD in the obsevation group was placed，and Cu IUD in the control group，effect of IUD between two groups were compared.Results Followed-up 12 months，occurrence of postoperation prolonged menstruation，menorrhagia，waist abdominal pain and abnormal vaginal bleeding in the obsevation group were obviously lower than those in the control group（P＜0.05）；compared with control group，occurrence of device displacement and prolapsed and pregnancy with IUD had no statistical differences（P＞0.05）；removal rate of IUD in the control group was higher than that in the obsevation group，but continued using rate in the obsevation group was 93.85%，higher than 81.54%in the control group，and the difference was statistically significant（P＜0.05）.Conclusion Immediately placing MYCu intrauterine device after abortion under B ultrasound monitoring，which adverse reaction is smaller，lower removal rate of IUD and sustainable use，isworthy of clinical application. 2016 Vol. 23 (27): 79-81 [Abstract] ( 140 ) HTML (36 KB)  PDF  (0 KB)  ( 29 ) 82 Effect observation of Omeprazole quadrup le therapy in children with peptic ulcer combined with Helicobacter pylori infection ZHOU Shu-gen Objective To explore the curative effect of Omeprazole quadruple therapy in children with peptic ulcer combined with Helicobacter pylori infection.Methods 70 children with peptic ulcer combined with Helicobacter pylori infection treated in our hospital from May 2013 to December 2015 were selected and randomly divided into observation group and control group，35 cases in each group.Control group was given triple therapy including Clarithromycin，Amoxicillin and Omeprazole，while observation group was given quadruple therapy including Bismuth potassium citrate，Clarithromycin，Amoxicillin and Omeprazole.The clinical efficacy of two groups were compared and analyzed.Results The total effective rate of control group was 77.14%，which was significantly lower than 94.29%of observation group　（P＜0.05）；the ulcer healing rate and the pain relief rate of observation group was 80.00%and 88.57%respectively，which was significantly higher than 54.29%and 48.57%of control group，while the adverse reaction rate of observation group was 5.71%，which was significantly lower than 22.86%of control group（P＜0.05）；The positive checked rate of helicobacter pylori of observation group was 5.71%，which was significantly lower than 25.71%of control group　（P＜0.05）.Conclusion Omeprazole quadruple therapy for children with peptic ulcer combined with Helicobacter pylori infection has significant efficacy.It can quickly eradicate Helicobacter pylori，relieve patients＇pain，effectively control infection，make ulcer surface quickly heal，reduce adverse reactions of drugs，shorten recovery time，improve patients＇living quality，which isworthy of clinical generalization and application. 2016 Vol. 23 (27): 82-84 [Abstract] ( 100 ) HTML (36 KB)  PDF  (0 KB)  ( 29 ) 85 Effect of lym phocyte active immunotherapy on blocking antibody in unexp lained recurrent spontaneous abortion WANG Dong-yan;LIMan-lan;HUANG He Objective To discuss the effect of lymphocyte active immunotherapy on blocking antibody in unexplained recurrent spontaneous abortion.Methods 112 patients with unexplained recurrent spontaneous abortion treated in our hospital from May 2014 to November 2015 were selected as the research subjects and divided into study group and control group with using single method，with 56 cases in each group.Patients in the control group were given routine treatment，and patients in the study group were given lymphocyte active immunotherapy，treatment effects were compared in two groups.Results After the treatment of 3 times，4 times，positive rate of blocking antibody in the study group was higher than that in the control group（P＜0.05），and CD4+，CD4+/CD8+，CD16+CD56+decreased，while CD8+increased in two groups，which weremore obvious in the study group than that in the control group　（P＜0.05）.The success rate of pregnancy was 64.29%in the study group，higher than 42.68%in the control group（P＜0.05）.Conclusion Clinical treatment effect of lymphocyte active immunotherapy is significant in the treatment of blocking antibody in unexplained recurrent spontaneous abortion，which can effectively improve positive rate of blocking antibody.It isworthy of promotion.  2016 Vol. 23 (27): 85-87 [Abstract] ( 118 ) HTML (44 KB)  PDF  (0 KB)  ( 34 ) 88 Study of diagnosis and treatment method of bacterial vaginosis in the clinic HE Li;TANG Yan-ping Objective To explore the diagnosis and treatmentmethod of bacterial vaginosis in the clinic.Methods 60 cases of bacterial vaginosis treated in gynaecological clinic in our hospital from February 2014 to January 2015 were retrospectively analyzed，in which 30 patients were as control group by Po Metronidazole and vaginal application of Metronidazole treatment，30 patients as observation group by Po Metronidazole and vaginal application of vaginal Dingjunsheng　（Lactobacillus viable Capsule）treatment.Clinical efficacy，recurrence rate and incidence of adverse reactions of two groups were compared in gynecological clinic.Results Total improvement rate，relapse rate and adverse reaction rate in the observation group were superior to those in the control group（96.67%vs 70.00%，10.00%vs 40.00%，6.67%vs 30.00%）（P＜0.05）.Conclusion Amsel"gold standard"method can give a fast and efficient diagnosis for patients with bacterial vaginosis，after diagnosis，to take immediate application of Po Metronidazole and vaginal Dingjunsheng treatment program，compared with a single administration of Metronidazole ismore effective，and safety is high，which isworthy of popularization and application in clinic. 2016 Vol. 23 (27): 88-90 [Abstract] ( 102 ) HTML (38 KB)  PDF  (0 KB)  ( 43 ) 91 The effect of postural guidance before and after cesarean section in improving breastfeeding success rate of cesarean section maternal GUO Fang-fang;HUANG Yan-fen Objective To study and explore the effect of postural guidance before and after cesarean section in improving breastfeeding success rate of cesarean section maternal.Methods From January 2013 to December 2015，100 cases of pregnantwomen given selective cesarean section with high risk factors of pregnancy department of obstetrics in our hospital were selected as the research object and divided into control group and observation group by random number table，each group had 50 cases.The control group had received the routine nursing，the observation group had received prenatal breastfeeding posture training and postpartum feeding posture guidance on the basis of routine nursing.On the postpartum first days，second days，third days，the maternal milk secretion and the success rate of breast feeding were compared between two groups，and the nursing satisfaction was compared between two groups.Results On the postpartum first days，thematernalmilk secretion and breastfeeding success rate were compared between two groups，and the difference was not statistically significant（P＞0.05）；On the postpartum second days，third days，thematernalmilk secretion and breastfeeding success rate in the observation group were significantly higher than those in the control group　（P＜0.05）. The nursing satisfaction ofmaternal in the observation group was 98%，compared with the control group of 86%，the difference was statistically significant（P＜0.05）.Conclusion Before and after the cesarean section，the implementation of prenatal breastfeeding posture guidance can effectively promote thematernalmilk secretion，increase the success rate of caesarean baby breastfeeding. 2016 Vol. 23 (27): 91-93 [Abstract] ( 119 ) HTML (38 KB)  PDF  (0 KB)  ( 30 ) 94 Clinical app lication of intraoperative ultrasound in the treatment of glioma ZONG Zhi-tao Objective To explore the clinical application of intraoperative ultrasonography in glioma therapy.Methods 100 caseswith glioma patients from April 2013 to February 2014 in our hospitalwere selected as research subjects，according to the random number table method，they were divided into control group and observation group，50 cases in each group.The control group was used the traditional surgical approach，surgical data were based on MRIor CT preoperative；observation group was used intraoperative ultrasound imaging to help implement surgery.KPS score and surgical time，the extent of tumor resection，postoperative survival after treatmentwere compared.Results The proportion of total resection surgery of observation group ratio was 78.00%，it wasmuch greater than that of control group 46.00%　（P＜0.05）.After surgery，KPS of observation group was（85.3±8.9）scores，it was significantly higher than that of control group（73.2±7.9），and average operation time of observation group was（5.6±1.4）h，it was significantly less than that of control group　（6.6±3.3）h（P＜0.05）.After follow-up of patients，survival rate of observation group was 98.00% after 1 year and 2 years，the survival rate was 88.00%（P＜0.05）.In observation group，43 cases intraoperative ultrasonography cavity and surrounding tissues with or without residual tumor results was same with the pathological diagnosis and 32 cases of control group，diagnostic coincidence rate was 86.00%and 64.00%.the diagnosis rate was higher than that of observation group　（P＜0.05）.Conclusion Intraoperative ultrasound can accurately locate in glioma surgery and improve diagnostic accuracy，also，it can ensure smooth operation and improve the quality of operation，the prognosis. 2016 Vol. 23 (27): 94-96 [Abstract] ( 127 ) HTML (40 KB)  PDF  (0 KB)  ( 40 ) 97 App lication of　“sandw ich cake embolism method”in the treatment of interventional embolization　in　the　treatment of　segmental artery hemorrhage of digestive tract WANG Yi; ZHANG Zhi-qiang;XIAO Bo Objective To explore the application effect of"sandwich cake embolism method"in the treatment of interventional embolization in the treatment of segmental artery hemorrhage of digestive tract.Methods From January 2013 to December 2015，80 patients with gastrointestinal bleeding in the gastrointestinal tract were divided into observation group and control group according to the differentmethod of treatment，40 cases in each group.The observation group was treated with"sandwich cake embolism"，and the control group was treated with a single embolization material.The effect of the two groups of surgery was observed.Results In the observation group，a successful hemostasis rate was 100%，no death patients，the recurrence rate was 10.0%；the control group a hemostatic success rate was 77.5%，with a mortality rate was 5.0%，recurrence rate was 22.5%，two groups of a hemostatic success rate，relapse rate，mortality was compared（P＜0.05）；the observation group recovered well accounted for 90.0%，control group was 55.0%，the difference was significant（P＜0.05）；pancreatin heighten，early rebleeding complication of control group were obviously higher than those of observation group（P＜0.05）；hospitalization time，cost of hospitalization of observation group were significantly lower than those of control group（P＜0.05）.Conclusion It is effective to treat the arterial hemorrhage of the digestive tractwith the sandwich embolization method，which can improve the success rate of embolization and decrease the rate of postoperative bleeding. 2016 Vol. 23 (27): 97-100 [Abstract] ( 108 ) HTML (46 KB)  PDF  (0 KB)  ( 37 ) 101 Curative effect evaluation on Methotrexate in combination with M ifepristone in treatment of ectopic pregnancy LIU Xiao-qin;LIANG Qing-yun Objective To study the effect on Methotrexate in combination with Mifepristone in treatment of ectopic pregnancy.Methods 100 cases of ectopic pregnancy patients between January 2013 to January 2016 in Department of Obstetrics and Gynecology in our hospital between were chosen as observation object，and were randomly divided into controlgroup and research group，controlgroup wasgiven Methotrexate therapy，research group was treated with Methotrexate combined Mifepristone，the clinical efficacy of two groups of patientswere retrospectively analyzed.Results The serum beta HCG levelswith different period　［7 d：（448.67±25.06）IU/L，14 d：（143.10±22.54）IU/L］，recovery time of beta HCG［（20.0±2.4）d］and total effective rate　（92%）in research group after treatment were significantly better than those of control group［7 d：（915.46±25.13）IU/L，14 d：（282.40±43.24）IU/L；（26.0±2.4）d；80%］（P＜0.05）.Conclusion Patients with ectopic pregnancy treated with Methotrexate combined Mifepristone，has a relatively satisfactory results，and it can improve the indicators and helpful to the patients. 2016 Vol. 23 (27): 101-103 [Abstract] ( 135 ) HTML (39 KB)  PDF  (0 KB)  ( 37 ) 104 Effectof Vildagliptin with Metform in on glucosemetabolism in patientswith polycystic ovary syndrome with abnormal endocrine and lipid metabolism JIChan Objective To explore the effect of Vildagliptin with Metformin on glucosemetabolism in patientswith polycystic ovary syndrome with abnormal endocrine and lipid metabolism.Methods 92 cases of patientswith abnormal glucose metabolism in Shenzhen Hengsheng Hospital for the diagnosis and treatment of PCOS from July 2014 to July 2015，were randomly divided into observation group and control group，46 cases in each group.The control group was given Metformin treatment，observation group was treated with Vildagliptin and Metformin，for 6 months of continuous treatment，the effectwas compared between the two groups of patients.Results The serum level of T in observation group was significantly lower than that in the control group　（P＜0.05），and the two groups of other endocrine indexes did not change significantly　（P＞0.05）；FPG after themeal，2 h PG and HbA1c in the observation group was significantly lower than that in the control group respectively　（P＜0.05）；LDL-C and TG levels in the observation group was significantly lower than that before treatment（P＜0.05），LDL-C and TG levels in the control group before treatment had no significant change　（P＞0.05）.Conclusion For PCOS patientswith abnormal glucosemetabolism treated with combination treatment of Vildagliptin and Metformin，can significantly improve the endocrine，metabolism of glucose and lipidmetabolism，it is a kind of effective treatmentmethod. 2016 Vol. 23 (27): 104-106 [Abstract] ( 127 ) HTML (37 KB)  PDF  (0 KB)  ( 40 ) 107 Clinical observation on Aricept combined with Oxiracetam for cognitive im pairment in convalescence in patientswith cerebral infarction LIN Peng-xing;MA Heng-zhang;SHIZhi-feng Objective To investigate the clinical effect of Aricept combined with Oxiracetam in treatment of cerebral infarction after cognitive impairment.Methods 84 cases diagnosed as suffering from cerebral infarction and associated with cognitive disorder in our hospital in June 2014 to February 2016 were divided into two groups，44 cases in the observation group，40 cases in the control group，the course of treatment in the control group were only taken Oxiracetam，orally twice daily，each 800 mg，and observation group was treated with oral processing applications combined with Oxiracetam drugs，including Aricept every night before going to bed，taking 5 mg，Oxiracetam dosage was the same as that of the control group.Two groups of treatment duration was 21 d for a course of treatment.Before and after treatment，the simple intelligent status scale　（MMSE）and the daily life activity scale　（ADL）in the two groups of patientswere compared.Results After treatment，the two groups of patientswith MMSE and ADL were better than before treatment，the observation group and control group patients in cognitive impairment improvement had statistical difference　（P＜0.05）.The total effect rate of observation group　（81.7%）was higher than that of control group，with significant difference　（P＜0.05）.Conclusion Aricept combined with Oxiracetam in treatment of cerebral infarction patientswith cognitive impairment has obvious effect，it can improve the ability in patients with activities and the level of quality of life，with curative effect，and has promotion value. 2016 Vol. 23 (27): 107-109转112 [Abstract] ( 126 ) HTML (41 KB)  PDF  (0 KB)  ( 31 ) 110 Effect analysison Tigecycline in treatment of ICU patientswith pulmonary infection by pandrug-resistant Acinetobacter baumannii LIU Bin-sen;KANG Kun-bo Objective To analyze the therapeutic effect Tigecycline in treatment of ICU patients with pulmonary infection by pandrug-resistant Acinetobacter baumannii.Methods 80 patientswith pulmonary infection by pandrug-resistant Acinetobacter baumannii from May 2014 to June 2015 in ICU of our hospitalwere divided into two groups，40 cases in each group.The control group was treated with Amikacin，the observation group was treated with Tigecycline.The total efficiency and CRP，PCT，WBC between two groups after treatment were compared.Results The total efficiency in the observation group after treatmentwas 87.50%，significantly higher than that in the control group of 50.00%，CRP of the observation group［（44.56±8.23）mg/L］，PCT［（3.54±1.77）μg/L］，WBC［（16.33±5.27）×109/L］was significantly better than that in the control group［（50.21±13.04）mg/L，（8.77±1.68）μg/L，（18.89±5.63）×109/L］（P＜0.05）.Conclusion ICU patientswith Tigecycline against pandrug-resistant Acinetobacter baumannii has a good therapeutic effect of pulmonary infection，and can effectively reduce the CRP，PCT and WBC level，increase the total efficiency，promote the patient recover fast，which isworthy of further clinical promotion and application. 2016 Vol. 23 (27): 110-112 [Abstract] ( 110 ) HTML (38 KB)  PDF  (0 KB)  ( 29 ) 113 Treatment effect observation　of Metoprolol tartrate combined　with W enxin Granule on arrhythm ia of coronary heart disease ZHOU Qiong;HE Shui-dai; HAN Yan Objective To investigate the therapeutic effect of Metoprolol combined with Wenxin Granule on arrhythmia of coronary heart disease.Methods Clinical data of 67 cases of arrhythmia in coronary heart disease patients in our center from March to December 2015 were retrospectively analyzed，33 cases using tartaric acid Metoprolol in the treatment of patients were chosen as the control group，34 patients using tartaric acid Metoprolol combined with Wenxin Granule in the treatmentwere chosen as in the observation group.The therapeutic effect of two groups of patientswas observed，clinical controlwas analyzed.Results The total effective rate，incidence of adverse reactions，frequency of arrhythmia and duration of the patients in the observation group　［88.2%，23.5%，（8.6±2.5）times，（3.1±0.5）h］were significantly better than those in the control group［66.7%，21.2%，（15.1±5.2）times，（6.1±1.6）h］，with significant difference（P＜0.05）.Conclusion The treatment effect of Metoprolol tartrate combined with Wenxin Granule on arrhythmia of coronary heart disease is good，worthy of clinical application. 2016 Vol. 23 (27): 113-115 [Abstract] ( 142 ) HTML (38 KB)  PDF  (0 KB)  ( 34 ) 116 Observation on the curativeeffectof BenazeprilHydrochloride Tablet combined with Jinshuibao Capsule in the treatment of early diabetic nephropathy GUO Tao;YISong-gang Objective To observe the curative effect of Benazepril Hydrochloride Tablet combined with Jinshuibao Capsule in patientswith early diabetic nephropathy by determining the serum cystatin C　（CysC），urinary albumin excretion rate　（UAER）.Methods 108 patients in our hospital from July 2014 to December 2015 according to treatmentmethods were divided into group A，group B，group C，group D，group A received conventional therapy，and the group B was given plus Benazepril Hydrochloride Tablet，group C was given Jinshuibao Capsule，group D Benazepril Hydrochloride Tablet and Jinshuibao Capsule.The serum CysC and UAER values in 4 groups before and after treatmentwere compared.Results After treatment，the serum CysC and UAER value of group B，group C，group D，were significantly decreased，compared with that before treatment and group A were statistically significant（P＜0.05）；there was significant difference in group D and B compared with group C　（P＜0.05）.After treatment，beta 2-MG，TG，TC in group B，group C had no significant difference（P＞0.05），butwas better than that of group A（P＜0.05）；group D of the three indicatorswere better than the other three groups（P＜0.05）.Conclusion The combination of Benazepril Hydrochloride Tablet and Jinshuibao Capsule in early diabetic nephropathy can effectively reduce the serum levels of CysC，UAER，and improve renal function. 2016 Vol. 23 (27): 116-118 [Abstract] ( 127 ) HTML (34 KB)  PDF  (0 KB)  ( 30 ) 119 Clinical observation of Nifedipine Controlled Released Tablets combined with Benazepril in the treatment of elderly hypertension ZHANG Na Objective To discuss the feasibility of the therapeutic protocol of Nifedipine Controlled Released Tablets combined with Benazepril，so as to reduce the fluctuations of blood pressure and prevent the incidence rate of all types of complications in the elderly patientswith hypertension.Methods 100 elderly patientswith hypertension whowere admitted to our hospital from March 2015 to March 2016 were selected as research subjects according to the randomization principle，and they were assigned into the control group and the experiment group by draw lots，with 50 patients in each group.All the enrolled patients were orally given Benazepril，and the experiment group was also given Nifedipine Controlled Released Tablets at the same time.The antihypertensive effect of different therapeutic protocols was compared between the two groups.Results The total effective rate in the experiment group（96.00%）was better than that in the control group（76.00%），and the difference between the two groupswas statistically significant（P＜0.05）；the diastolic pressure and systolic pressure in the experiment group before drug administration was（110.7±12.2）and　（165.4±14.7）mmHg respectively，and the diastolic pressure and systolic pressure in the control group before drug administration was （112.4±12.4）and（166.2±15.3）mmHg respectively；after the treatment，the diastolic pressure and systolic pressure in the experiment group was（70.5±11.8）and（122.2±12.4）mmHg respectively，and the diastolic pressure and systolic pressure in the controlgroup was（88.7±13.4）and（145.1±13.1）mmHg respectively.The reduction in the experimentgroup wasmore significant，and the differences between the two groups were statistically significant（P＜0.05）.Conclusion During the treatment course of elderly hypertension，the application of Nifedipine Controlled Released Tablets combined with Benazepril is helpful for improving the antihypertensive effects，reducing fluctuations of blood pressure and the incidence rate of adverse events，which is highly effective and worthy of clinical promotion and application. 2016 Vol. 23 (27): 119-121 [Abstract] ( 112 ) HTML (36 KB)  PDF  (0 KB)  ( 18 ) 122 Study on quality standards of Qingruxiao particles ZENG Hai-song;YU Jie-dong;SHAO Qui-hong Objective To establish the quality standard of Qingruxiao particles.Methods Green Tangerine Peel，Prunella vulgaris Linn，Fritillaria thunbergii，Boswellia carteri were identified by TLC，and rosmarinic was determined by HPLC. Results TLC spots developed were fairly clear，and the blank test showed no interference.The linear range of rosmarinic was between 1.26 and 40.36μg/ml（r=0.99995，n=6），and the average recoveries was 101.2%，RSD was 0.84%（n=6）.The method was simple，high sensitivity，good reproducibility and reliable.Conclusion The detection method can be used as the determination of the rosmarinicin Qingruxiao particles. 2016 Vol. 23 (27): 122-125 [Abstract] ( 130 ) HTML (44 KB)  PDF  (0 KB)  ( 38 ) 126 Quality standard of 0.01%atropine sulfate eye drops LIU Jian;YAN Jian-kun Objective To establish the quality standard for 0.01%atropine sulfate eye drops.Methods Atropine sulfate content in the formulation was quantitatively determined by HPLC tometry.Results The linear range of atropine sulfate was l0 to 60μg/ml（r=0.9999）.The average recovery rate was l00.4%（RSD=0.3%，n=9）.Conclusion By HPLC tometry，this is a easy，precise and repeatable method.It can be used as a quality control for the 0.01%atropine sulfate eye drops. 2016 Vol. 23 (27): 126-128 [Abstract] ( 229 ) HTML (38 KB)  PDF  (0 KB)  ( 30 ) 129 Observation on the effect of acupuncture and moxibustion in treating peripheral facial paralysis FU Lei Objective To investigate the effect of acupuncture and moxibustion in treating peripheral facial paralysis. Methods A total of 90 cases of peripheral facial paralysiswho were treated in the hospital from February 2013 to January 2014 were retrospectively analyzed and divided into control group and observation group according to the treatmentmethods，with 45 cases in each group.Peripheral facial paralysis patients in control group were given with western medicine treatment；while，observation group accepted acupuncture and moxibustion treatment.The function of House-Brackmann（H-B）facial nerve grading scale，FDIP score（facial disability index，physical functions），FDIS（facial disability index，social functions）and the clinical curative effect of two groups of patientswere observed.Results The total improvement rate of peripheral facial paralysis patients in observation group was 86.67%，better than 55.56%in control group，and the differencewas statistically significant（P＜0.05）.The H-B facial nerve function score，FDIP score and FDIS score in the observation group were better than those in the control group，the difference were statistically significant （P＜0.05）.Conclusion Application of acupuncture and moxibustion in patientswith peripheral facial paralysis can effectively improve facial nerve functions and clinical curative effects of peripheral facial paralysis patients，with high safety and significant effects，which isworthy ofwider promotion in clinical implementation. 2016 Vol. 23 (27): 129-131 [Abstract] ( 108 ) HTML (40 KB)  PDF  (0 KB)  ( 35 ) 132 Effect analysis of Qingfei diuresis therapy on patients with chronic non bacterial prostatitis QIU Chun-lan;ZHUANG Jing-hui;QIU Li-yun Objective To investigate the therapeutic effect of Qingfei diuresis for chronic non bacterial prostatitis.Methods 98 patients with chronic non bacterial prostatitis reated by Qingfei diuresis from January 2012 to December 2015 were selected，and before and after treatment symptoms improved and hormone expression level were compared.Results Clinical cure were 61 cases，markedly effective were 20 cases，effective were 15 cases，invalid were 2 cases，the total effective rate was 97.96%.Before treatment in patients with testosterone expression level［（1.94±0.41）ng/ml］，was significantly lower than that of after treatment［（3.64±1.04）ng/ml］，with significant difference（P＜0.05）.After the treatmentwith estradiol expression levels for（32.38±9.42）pg/ml，significantly higher than（10.46±3.16）pg/ml of before treatment，with significant difference（P＜0.05）.Conclusion Qingfei diuresis can effectively improve the clinical symptoms of the patients with chronic non bacterial prostatitis and itsmechanism may be through regulating hormone expression. 2016 Vol. 23 (27): 132-133 [Abstract] ( 101 ) HTML (32 KB)  PDF  (0 KB)  ( 32 ) 134 Effect observation of Shufeng Jiedu capsules in the treatment of community-acquired pneumonia ZHU Dong-quan;LIQing-xian Objective To evaluate the clinical efficacy and safety of Shufeng Jiedu capsules in the treatment of community-acquired pneumonia（CAP）.Methods 120 cases of CAP in the department of respiration of the third people＇s hospital of Zhengzhou city from January 2015 to January 2016 were randomly divided into the treatment group and the control group.The control group received levofloxacin injection，0.6 g/d，treatment 7 to 14 days.On the basis of the control group，the treatment group was given Shufeng Jiedu capsules，4 pills/time，3 times/d，7 to 14 days.Themain clinical symptoms and signs of infection-related indicators，chest X-ray changes，clinical effects，adverse reactions were observed before and after treatment in hospital for several days.Results Compared with the control group，the main clinical symptoms，signs of infection and recovery time of the treatment group was significantly shorter.And leukocytes，neutrophils rate，C-reactive protein，procalcitonin and other infection-related indicators was decreased significantly in the third day after treatment（P＜0.05），the seventh day returned to normal.Ray absorption prompt treatment of inflammatory lesions group was significantly higher（P＜0.05）.Both groupswere no adverse reactions.Conclusion Shufeng Jiedu capsules combined levofloxacin injection in the treatment of community-acquired pneumonia can contribute to the improvement of clinical symptoms，accelerate recovery infection indicators and shorter hospital stays. 2016 Vol. 23 (27): 134-136 [Abstract] ( 113 ) HTML (45 KB)  PDF  (0 KB)  ( 37 ) 137 Clinical observation of short needling technique of Chinesemedicine long need le acupuncture to cure the pain accom pany with numb of lumbar disc herniation DONG Jian-jun;ZHANG Pan;ZHANG Gui-feng Objective To observe the clinical effectof the Chinesemedicine long needle acupuncture technique in treating lumber disc herniation.Methods 200 patientswith lumber disc herniation in our hospital from October 2014 to October 2015 were divided into treatment group and control group by hospital number，with 100 cases in each group.The treatment group used the Chinese medicine long needle acupuncture technique to treat，every seven days treat once，twice was one course of treatment.Control group used the traditional acupuncture and tuina，once for every day，ten days was one course of treatment.The curative effectafter two courses of treatment between two groupswas evaluated.Results The total effective rate of treatment group was 98%，higher than 83%in control group，with statistical difference（P＜0.05）. Before treatment，the VAS scores of the two groups was not statistical difference（P＞0.05）；after treatment，VAS scores of two groupswas compared，the differencewas statistically significant（P＜0.05）.Therewere outstanding effect in clinical to use the Chinesemedicine long needle acupuncture technique to treat lumber disc herniation.Conclusion It is safe and effective to use the short needling technique of Chinesemedicine long needle acupuncture to treat lumber disc herniation，it isworth to popularization and application it in clinic. 2016 Vol. 23 (27): 137-139 [Abstract] ( 134 ) HTML (46 KB)  PDF  (0 KB)  ( 29 ) 140 App lication on combination of traditional Chinesemedicine foot bath and foot acupointmassage in the treatment of insomnia patients with stagnation of liver fire type LIU Li-hua;XIAO Dan Objective To observe the effect of application on combination of TCM　（Traditional Chinese Medicine）foot bath and foot acupointmassage in treatment of insomnia patients with stagnation of liver fire type.Methods 125 patients with stagnation of liver fire type treated in the hospital from January 2013 to December 2015 were selected as the subjects of this research and were randomly divided into experiment group（75 cases）and control group（50 cases）. The control group was simply treated with hot feet bath；while，the experiment group was administered with combination of TCM foot bath and foot acupointmassage.The Pittsburgh sleep quality index and curative effect of two groups postoperatively were observed.Results After treatment，the total efficiency of experiment group（93.33%）was higher than that of control group（70.00%），with statistical difference（P＜0.05）.The sleep quality of experiment group was improved more obviously，with significantly decreased sleep quality index scores and total scores in contrast with control group　（P＜0.05）.Conclusion Application of traditional Chinese medicine foot bath and foot acupointmassage can effectively improve the quality of sleep in insomnia patientswith of stagnation of liver fire type. 2016 Vol. 23 (27): 140-142 [Abstract] ( 160 ) HTML (41 KB)  PDF  (0 KB)  ( 33 ) 143 Analysis on efficacy of Chige soup in treating different cervical spondylosis YU Da;GAO Xiu-xian;TANG Zhao;WAN He-bin;WANG Xiao-ying;CHEN Ying;YU Hong-bin;WEIHui Objective To analyze the effect of Chige soup in treating different cervical spondylosis.Methods 240 outpatients with cervical spondylosis patientsmeet the conditions from January 2014 to May 2016 were selected as the research object.They were randomly divided into observation group and control group，120 cases in each group.The control group was treated with conventional therapy，observation group was treated Chige soup，the treatment effectwas analyzed. Results In the course of treatment，all patientswere well tolerated and no adverse reactions.The patients in the observation group of nerve root type was 96%，cervical vertebra disease ratewas 97%，vertebral artery type rate was 96%，higher than 70%，69%，58%in the control group，the difference was statistically significant（P＜0.05）；the sympathetic type rate of observation group was 89%，compared with 70%in the control group，the difference was not statistically significant（P＞0.05）.Conclusion Chige soup is suitable for the treatment of cervical type，nerve root type，vertebral artery type of cervical spondylosis，it isworth promoting. 2016 Vol. 23 (27): 143-145转148 [Abstract] ( 95 ) HTML (40 KB)  PDF  (0 KB)  ( 32 ) 146 Clinical effect analysis of Fumai Yangxin decoction in the treatment of chronic arrhythm ia HONG Hao-xiang Objective To study the effect of Fumai Yangxin decoction in the treatment of chronic arrhythmia.Methods 50 patientswith chronic arrhythmia in our health service center from April 2014 to August 2015 were selected.According to the random number tablemethod，50 patients were randomly divided into Xinbao pill group and Fumai Yangxin group，with 25 cases in each group.All patients were given nutrition myocardium，anticoagulant and lipid conventional symptomatic treatment.On this basis，Xinbao pill group were given Xinbao pill；Fumai Yangxin group received Fumai Yangxin Decoction.The treatment of chronic arrhythmia total efficiency，symptoms of adverse drug reaction occurred，the difference before and after intervention in patients with arrhythmia symptom score，heart beats perminute between two groupswere compared.Results①The total effective rate of the treatment of chronic arrhythmia in Fumai Yangxin group was higher than that of Xinbao pill group，the difference was statistically significant（P＜0.05）.②Incidence of adverse reactions in Fumai Yangxin group was lower than thatof Xinbao pill group（P＜0.05）.③Before intervention，arrhythmia symptom score，heart rate between two groups was not statistically significant　（P＞0.05）.After intervention，the arrhythmia symptom score，heart rate significantly of Fumai Yangxin group was better than that of Xinbao pill group respectively（P＜0.05）.Conclusion Fumai Yangxin decoction in treating chronic arrhythmia has exact effect，safety function，less side effect，is beneficial to the prognosis of the patients，is the ideal choice for treatment of patientswith chronic arrhythmia. 2016 Vol. 23 (27): 146-148 [Abstract] ( 102 ) HTML (39 KB)  PDF  (0 KB)  ( 42 ) 149 Cerebral ischem ia-reperfusion induce G luR6 S-nitrosylation through neuronal NO synthase WANGMei;HU Xiao-tong;QIDa-shi;WANG Lei;ZHANG Fang Objective To discusswhether neuronal nitric oxide synthase induce KA receptor subunit GluR6 S-nitrosylation during ischemia-reperfusion.Methods 28 SD rats were randomly divided into 4 groups，each group had 7 rats：sham operation group，cerebral ischemia reperfusion 6 h combination with neuronal nitric oxide synthase inhibitor 7-NI group，cerebral ischemia reperfusion group，cerebral ischemia/reperfusion 6 h solvent control group.Transient cerebral ischemiawas induced by a four-vessel occluded　（4-VO）method.SD ratswere treated intraperitoneally with 7-Nitroindazole，an inhibitor of nNOS（7-NI，25mg/kg）.Biotin switch assay，SDS-PAGE and western blotwas performed to study S-nitrosylation and expression levels of GluR6.Results GluR6 S-nitrosylation levels in cerebral ischemia-reperfusion group increased significantly versus than that of sham group（P＜0.05）.GluR6 S-nitrosylation levels in cerebral ischemiareperfusion combination with neuronal nitric oxide synthase inhibitor 7-NI group descended significantly versus cerebral ischemia-reperfusion group，itwas significant difference　（P＜0.05）；however，GluR6 protein expression level was no significant difference among groups.Conclusion nNOS induce GluR6 S-nitrosylating during the early stages of ischemia-reperfusion，which can be a new theory basis for stroke therapy. 2016 Vol. 23 (27): 149-152 [Abstract] ( 105 ) HTML (46 KB)  PDF  (0 KB)  ( 32 ) 153 The correlation of P53,HER2 and K i-67 protein expression in gastric cancer ZHAN Rui Objective To investigate the expression，clinical significance，invasion andmigration of P53，HER2 and Ki-67 in gastric cancers.Methods 142 cases gastric cancerswere collected from November 2012 to December 2015 of department of pathology.Immunohistochemistry was used to detect the expression of P53，HER2 and Ki-67 in 142 cases of gastric cancer.The correlation between their expression and pathologic parameters were analyzed by statistics.Results The positive rate of P53，HER2 and Ki-67 in 142 cases of gastric cancer was 70.42%，83.10%and 32.39%respectively.The differences of the expression of P53 in tumor size，different histological grading group，the Lauren classification，lymph nodemetastasis group and vascular invasion group were statistically significant（P＜0.05）；the expression of HER2 was statistically associated with different histological grading group，the Lauren classification，different depth of invasion，lymph nodemetastasis group and vascular invasion group（P＜0.05）；the expression of Ki-67 was statistically associated with different histological grading group，the Lauren classification，different depth of invasion，lymph nodemetastasis group（P＜0.05）.The expression of P53 was positively correlated with Ki-67（P＜0.05），and so did HER2（P＜0.05）.Conclu-sion Combined detection of P53，HER2 and Ki-67 has very important significance in judging prognosis and guiding clinical treatment of gastric cancer. 2016 Vol. 23 (27): 153-155 [Abstract] ( 128 ) HTML (33 KB)  PDF  (0 KB)  ( 36 ) 156 Investigation and im provementmeasures of operation situation of hospital in colleges and universities SUN Yin-xuan;SHEN Ting;RONG Xiao-chan;XU Xiao-chan;ZHANG Bi-xing;TANGQi-min;LIWen-yan;SUN Jun-zhong Objective To investigate the diagnosis and treatment experience of college students in the college hospital, and to put forward reasonablemeasures to improve the hospitalmedical treatment.Methods The data acquired from the questionnaire survey from March the 1stto the 30thday 2016 in the five universities of Guangzhou City was analyzed to establish a service function analysismodel of college hospitals.Results Many issueswere found in the operation of col-lege hospitals,including highmisdiagnosis rate,to-be-improved satisfaction degree and poor credibility etc..Conclusion To strengthen the training of staff skills training and provide adequate system guarantee are an inevitable requirement for the good operation of hospital. 2016 Vol. 23 (27): 156-159 [Abstract] ( 126 ) HTML (50 KB)  PDF  (0 KB)  ( 30 ) 160 Survey of exercise-induced gastrointestinal syndrome of college students ZHONG Li-lan;HAO Shan;ZENG Xiao-qiong;ZHANG Zhi-qiang;LIN Xiao Objective To explore the occurrence and corresponding influencing factors of exercise-induced gastrointesti-nal syndrome(EIGS),and tomore comprehensively and depth understand EIGS.Methods Stratified cluster sampling was applied to survey on college students of some college from September 2013 to July 2015,and main contents involved gender,grade,exercise and diet and the occurrence of gastrointestinal symptoms.Results The proportion ofmale students suffering fro　MeIGSwas 35.31%(1430/4050),while that proportion of female studentswas 39.80%(1572/3950).The in-cidence of students suffering from EIGS in first grade was 43.5%(1746/4013),higher than 39.8%(1587/3987)in second grade,and the difference was statistically significant(P＜0.01).Among college students suffering from EIGS,the incidence of nausea was 43.21%(1787/4136),abdominal pain with 33.56%(1388/4136),emesis with 27.68%(1145/4136),nausea with 21.64%(895/4136)and fever at 10.15%(420/4136),which were common symptoms.The running,cycling,basketball and badminton games were four sports that students normally participated in.The incidence of female college students suffering EIGS was higher than that ofmale college students for these four games,and the difference was statistically significant(P＜0.01).Conclusion EIGS is related to gender,grade,sports status and medical history,all the teachers and students should be alert to hazard of such disease. 2016 Vol. 23 (27): 160-162 [Abstract] ( 119 ) HTML (37 KB)  PDF  (0 KB)  ( 34 ) 163 System integration survey and analysis of puerpera data of the new ly built hospital YUAN Qiao-qi;LICui-yuan;GANWei-hong;XIE Hua-feng;ZHONG Liu-ying Objective To analyze the prenatal and antenatal care,perinatal conditions of full term pregnant women of obstetrics department in one new general hospital,to provide the basis for the development ofmore effective pregnant womenmanagement and pregnancymanagementmode for the surrounding residents and to providemore detailed clini-cal data formore new hospital administrators and staff in the department of obstetrics and gynecology.Methods Data of 519 puerperawhowere hospitalized in our hospital and took term labor from April 2013 to December 2014 were retro-spectively analyzed and divided into group A and group B.Pregnantwomen in group A were registered permanent resi-dence in Guangdong Province and pregnant women in group B were registered provincial census.Maternal distribution and sources,the number of pregnancy and maternal and infant outcomes in two groupswere compared.Results Group A had more than group B including number of births(57.0%vs 43.0%),mogitocia(assisted breech delivery,clamp produc-tion operation),first give birth,neonatal Apgar score nomore than 7 scores,pregnantwoman in elder age and other high risk factors other than large infants;group B had more than group A including number of pregnancymore than 2 times and pregnantmore than 3 times and large infants.Conclusion The ratio of Guangdong Province registered permanent residence ismore than foreign population around the hospital peripheral area,further strengthening the knowledge of prenatal and prenatal care for women of childbearing age in Guangdong Province should be done to reduce the inci-dence of perinatal adverse outcomes. 2016 Vol. 23 (27): 163-165 [Abstract] ( 115 ) HTML (39 KB)  PDF  (0 KB)  ( 32 ) 166 Teaching practice and experience of human sectional and imaging anatom y HUANG Da-yuan;WU Guo-yun;LIANG Cheng-qing;XIANG Zhi-gang With the emergence and application of CT，MRIand X-ray technology，imaging of auxiliary examination has become an important part ofmodern medical technology.As a bridge curriculum ofmedical imaging technique specialty connected basic with clinic，the teaching difficulty coefficient of human sectional and imaging anatomy is larger than of other courses，and students need tomaster somany anatomical structure that it is difficult tomemory.How to adapt to the needs of society to carry out the human sectional and imaging anatomy teaching is an important problem that we need to face.In this article，combining with our school＇s situation of the human sectional and imaging anatomy teaching，we discussed from aspects of the reasonable design of teaching syllabus and teaching plan，selection of teachingmaterial，choice of course content，application of teachingmeans and teachingmethod，construction of laboratory and curriculum examination and so on，to improve the teaching quality of human sectional and imaging anatomy，and lay a good foundation for the latter part ofmedical education. 2016 Vol. 23 (27): 166-168 [Abstract] ( 110 ) HTML (36 KB)  PDF  (0 KB)  ( 33 ) 169 Constructing and im p lementing of a new type of the functional experiment teaching system LUO Xue-ya;ZENG Chang-qian;KANG Le;YANG Chun-guang;MA Jun-yan;GAO Wei;GAO Qing-bo;MIAO Ying-qiu In order tomeeting the basic requirments better of the undergraduatemedical education standards—clinical medicine（trial）for trainingmedical graduates and improving the quality of personnel training，on the basis of the original course system of the functional experiment in our school，the reformating，explorating and implementing were done from the aspects of teaching content，teachingmodel，and evaluation methods and so on through utilizing the thought of modern education teaching.A new type of the functional experiment teaching system was constructed，including optimizing the teaching contents，increasing the proportion of comprehensive and designable experiments，perfecting the evaluationmethodsof the curriculum，adopting the evaluationmethods of combining formative evaluation with summative evaluation，which could more fully reflect the students＇learning，renewing the traditional teachingmodel，increasing the virtual experiment project，realizing the combination of virtual and entity animal testing，revising the teaching program，compiling the experimental teachingmaterials etc.By constructing and implementing the new type of the functional experiment teaching system，this research promoted the development of the students＇innovative ability，practical ability and scientific research ability，especially autonomous learning ability，meanwhile it also laid the foundation for further enhancing the teaching level of functional experiment in our school and training high-qualitymedical talents. 2016 Vol. 23 (27): 169-171转180 [Abstract] ( 134 ) HTML (44 KB)  PDF  (0 KB)  ( 36 ) 172 The im pact effect of critical thinking ability by clinical nursing professional com petence training for clinical nurses CHEN Xiu-li;ZOU Xiao-yin Objective To evaluate the effect of critical thinking ability by clinical nursing professional competence training for clinical nurses.Methods 96 cases of nurse on staff in our hospital from May 2014 to May 2015 were selected，including 48 casesofnurseswere undergoing clinicalnursing professional competence training as the experimentalgroup；the other 48 cases nurseswere not received formal clinical nursing expertise training，for the control group.After the end of the training，the performance assessment results were observed，and using critical thinking ability scale were used to analyze the critical thinking ability evaluation of the two group of the nurses；and the rate of the common adverse events were observed.Results The theory examination scoresofexperimentalgroup nurseswas（95.44±3.87）points and practical skill scores was（96.13±3.33）points，which significantly higher than　［（85.19±3.91），（84.71±3.41）points］in the control group（P＜0.01）；the nurses seeking truth，open thinking，analytical ability，system the ability of thinking，self-confidence，inquisitiveness and cognitive maturity of critical thinking ability scores of experimental group were significantly higher than those in control group（all P＜0.01）；the total critical thinking ability score of experimental group was higher than that of the control group［（349.7±90.3）vs（305.8±90.2）points］（P＜0.05）.The incidence of adverse events in the experimental group was 4.17%（2/48），lower than 16.67%（8/48）in the control group，the difference was statistically significant （χ2=4.0186，P=0.0450）.Conclusion Clinical nursing competency training can improve the quality of care nurses，and can effectively improve the clinical nurse critical thinking ability of nurses and is useful to guide clinical care，reduce the incidence of adverse reactions. 2016 Vol. 23 (27): 172-174 [Abstract] ( 112 ) HTML (37 KB)  PDF  (0 KB)  ( 36 ) 175 Pharmaceutical care analysis in one case of tuberculous constrictive pericarditis LIZi-bo;WU Yan-fei;HUWen To formulating and implementing individualized pharmaceutical care to the patient，clinical pharmacists participated in one case of tuberculous constrictive pericarditis patients，adjusting the pharmaceutical care scheme in time according to the clinical effects of drugs by providing care analysis of drug use about anti-infection，diuretic，microcirculation and subsequent symptomatic treatment.The clinical pharmacists took effect of anti-infective drugs for patients with constrictive pericarditis heart and the interaction of each therapeutic agents as the entry point to carry out fullcourse pharmaceutical care，and to discover and solve problems during treatment to ensure the rationality，safety，and effectiveness ofmedication and improve the clinical cure rate.Some experience is accumulated in the anti-infective drug therapy and the interaction between the various drugs during this treatment about the tuberculous pericarditis patient，which is helpful to provide advice to clinical rational drug use and to exemplify the values of clinical pharmacists. 2016 Vol. 23 (27): 175-177 [Abstract] ( 119 ) HTML (36 KB)  PDF  (0 KB)  ( 29 ) 178 Reportof 1 case of secondary trocar port siteovarian cancermetastasisafter laparoscopic surgery for benign ovarian disease XU Jia-nan;CHEN Meng-kun;HE Xin-qin;DANG Zhi-xia A 43 years old female patientwas receeived a laparoscopic surgery to resect the right adenexa because of the right ovarian chocolate cyst 5 years and 10 months before admission（February 16，2010）.She presented with swelling pain and amass in her right laparoscopy trocar port site 4months before admission（August 1，2015）.Themass was excised on December 4，2015，and the pathology after excision revealed metastatic adenocarcinoma in the right rectusmusclemass，consistentwith ovarian serous carcinoma.This case suggested that，even in the laparoscopic surgery for benign ovarian diseases，there was still a risk of trocar port site ovarian cancermetastasis. 2016 Vol. 23 (27): 178-180 [Abstract] ( 115 ) HTML (31 KB)  PDF  (0 KB)  ( 35 ) 181 The treatment of a FAP patient with the im provement Soave laparoscopic surgery and total colorectal resection LILei;WANG Chang;CHEN Hong-Chun;CHEN Fei To introduce completely laparoscopic assisted incision surgery FAP 1 case in August 2015 our hospital.Firstly，the terminal ileum，the entire colon and the upper rectum were separated with laparoscope，the circular incision of rectalmucosawas on the 1 cm above of the dentate line，and 6 cm muscle sheath was cut off.Finally，the intestinal canal was dragged out from the anus by the rectalmuscle sheath，the ileum and dentate linewere anastomosed in the end.Results The diseased intestinal canal was successful transanal resection and anastomosis.And the anal function was also well after surgery. 2016 Vol. 23 (27): 181-183 [Abstract] ( 102 ) HTML (36 KB)  PDF  (0 KB)  ( 34 ) 184 Effect of emotional support and psychological nursing on depression and anxiety ofmalignant tumor patients HE Yu-e Objective To inveterate the emotional support and psychological nursing on depression and anxiety ofmalignant tumor patients.Methods 120 cases ofmalignant tumor patients from March 2014 to January 2016 were collected and divided into control group（60 cases）and observation group（60 cases）according to randomized.Starting in January 2015，added with emotional support to the clinical nursing and mental care.The control group was received routine nursing，the observation group was received emotional support and psychological nursing.The scores of Self-Rating Anxiety Scale，Self-Rating Depression Scale，Hamilton Anxiety Scale and Hamilton Depression Rating Scale between the two groupswere evaluated and compared.Results The scores of SAS and SDS in observation group were significantly lower than that of control group（P＜0.01），and the scores of HAMA and HAMD in observation group were significantly lower than that of control group（P＜0.01）.Conclusion The application of emotional support and psychological nursing can significantly improve the negative emotions ofmalignant tumor patients，improve confidence in the treatment and rehabilitation，it should bewidely applied. 2016 Vol. 23 (27): 184-186 [Abstract] ( 106 ) HTML (38 KB)  PDF  (0 KB)  ( 38 ) 187 The effect of fast track surgery in perioperative nursing care of patients with lumbar operation LIN Hai-yanl;LIXin;CHEN Xiu-qiong Objective To investigate the effect of fast track surgery in perioperative nursing care of patientswith lumbar operation.Methods 58 patients underwent lumbar posterior decompression and internal fixation from September 2015 to December 2015 in Fujian Provincial Hospital were included，and were randomly divided into the control group and the experimental group.The control group was used the traditional lumbar perioperative nursing，the experimental group was applied FTS for perioperationg nursing of lumbar spine surgery.Pain，time of getting out of the bed，complications，activities of daily living（ADL）score，hospitalization time and clinical efficacy were applied to compared between two groups. Results Patients in the experimental group after operation for pillows time，eating time，off bed activity time，hospitalization time were better than that of control group（P＜0.05）.Pain was statistically different between two groups in the first day and third day after operation（P＜0.05）.Urinary tract infection and pulmonary infection were statistically different between two groups　（P＜0.01）.The lower extremity venous thrombosiswere statistically different between two groups　（P＜0.05）.ADL score was statistically different between two groups in the first day and third day after operation（P＜0.05）. Conclusion Fast track surgery applied in perioperation nursing for lumbar surgery patients can significantly relieve postoperative early pain，shortening hospitalization time，reduce complications after lumbar surgery，which is worthy of promotion. 2016 Vol. 23 (27): 187-189 [Abstract] ( 92 ) HTML (43 KB)  PDF  (0 KB)  ( 43 ) 190 Observation of nursing effect of an elderly lumbar infection treated by vacuum sealing drainage combined with skin flap transfer FENG Yan-wen;DENG Xin-zheng;HUANG Jin-ru;LU Yan-hua Objective To explore nursing effect of an elderly lumbar infection treated by vacuum sealing drainage combined with skin flap transfer.M ethods A patients suffering from various chronic diseases among the elderly body bedsore，the waist back decubitus ulcers and infection，was cleared multiple trauma，and given VSD negative pressure drainage after flap transfer operation.Before and after surgery，the patientwas given effective psychological nursing，preoperative correctmalnutrition and postoperative attention to nutritional support，various pipeline nursing，posture nursing and observation of skin flap and complications prevention，guiding of the follow-up.Results After treatment and nursing，postoperative flap blood supply and blood supply were normal.There were no pale，purple，blood stasis or necrosis.The stitches did not occur after ulcer，wound completely healed after dressing change in 27 d.After operation，the patientwas followed up for 18 months，and the patient was normal during the follow-up.Conclusion The effective，systemic，highquality care plays a key role in flap transfer therapy with a variety of chronic diseases aged bedsore，reflecting the whole course nursingwork importance. 2016 Vol. 23 (27): 190-192转196 [Abstract] ( 117 ) HTML (41 KB)  PDF  (0 KB)  ( 25 ) 193 Nursing intervention in multip le rib fractureswith severe pulmonary contusion SUNMin;DING Chang-qing;BIWei Objective To explore the effect of nursing intervention in multiple rib fractures with severe pulmonary contusion，and to improve the recovery rate.M ethods From June 2014 to June 2016，60 patients with multiple fractured ribs and severe pulmonary contusion in the People＇s Hospital of Fengxian were included.According to the different nursingmethods，the patientswere divided into the control group　（n=30）and the study group　（n=30）.The control group was given conventional care，the study group was given personalized nursing intervention.After nursing，the clinical nursing curative effects in the two groupswere compared.Results The pain duration，mechanical ventilation time and bed activity time，chest drainage tube indwelling time and hospital stay in the study group were significantly shorter than that of normal group，the difference was significant（P＜0.01）；Lung function indexes such as PaO2，PaCO2in the study group were better than that of normal group，the difference was significant（P＜0.01）；The curative effect in the study group was significantly higher than that of normal group，the difference was significant（P＜0.01）.Conclusion Personalized nursing interventions is beneficial to the rehabilitation of patientswithmultiple rib fractures and severe pulmonary contusion，so it isworthy of application. 2016 Vol. 23 (27): 193-196 [Abstract] ( 121 ) HTML (44 KB)  PDF  (0 KB)  ( 35 )

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