特发性血小板减少性紫癜采用腹腔镜下脾切除术治疗的效果分析

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (41 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the effect of laparoscopic splenectomy in the treatment of idiopathic thrombocytopenic purpura.Methods 40 patientswith idiopathic thrombocytopenic purpura from January 2010 to January 2015 in our hospitalwere selected and randomly divided into the trial group and the control group，20 cases in each group.The control group was treated with traditional splenectomy，the trial group was treated with laparoscopic splenectomy.The therapeutic effect，the amount of intraoperative blood loss，operative time，length of hospital stay，recurrence rate and the incidence rate of complication in the two groups was compared.Results There was no significant difference in the total effective rate between the two groups（P＞0.05）.The amount of intraoperative blood loss in the trial group was less than that in the control group，the length of hospital stay in the trial group was shorter than that in the control group，the total amount of fluid infusion and the total hospital costs in the trial group was less than that in the control group，with significant difference（P＜0.05）.There was no significant difference in the operative time between the two groups（P＞0.05）.There was no significant difference in the recurrence rate between the two groups（P＞0.05）.The incidence rate of complication in the trial group was 15.0%，which was lower than 40.0%in the control group，with significant difference（P＜0.05）.Conclusion Laparoscopic splenectomy in the treatment of idiopathic thrombocytopenic purpura can effectively improve the patient＇s symptoms，operation is safe，with low recurrence rate，fewer complications，it has important clinical significance.

Key words： Idiopathic thrombocytopenic purpura Laparoscopic splenectomy Recurrence rate Complication Curative effect analysis

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	YIBo
	CHEN Xun
	TANG Cai-xi

Cite this article:

YIBo,CHEN Xun,TANG Cai-xi. Effect analysis of laparoscopic splenectom y in the treatment of idiopathic thrombocytopenic purpura[J]. 中国当代医药, 2016, 23(27): 40-42转64.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I27/40

［1］	Tabata R，Tabata C，Kita Y.Management of myocardial infarction in immune thrombocytopenic purpura with antiphospholipid antibodies［J］.JThromb Thrombolysis，2013，35 （1）：115-118.
［2］	Elhoseiny SM，Morgan DS，Elhadidy KE.The association of lymphoid protein tyrosine phosphatase non-receptor 22 （PTPN 22）gene polymorphism with Egyptian immune thrombocytopenic purpura［J］.Comparative Clin Pathol，2013，22（3）：395-402.
［3］	邵学谦.单孔腹腔镜脾切除术与传统腹腔镜脾切除术的对照研究［J］.中国内镜杂志，2014，20（20）：805-807.
［4］	Talaat RM，Elmaghraby AM，Barakat SS，et al.Alterations in immune cell subsets and their cytokine secretion profile in childhood idiopathic thrombocytopenic purpura（ITP）［J］.Clin Exp Immunol，2014，176（2）：291-300.
［5］	马利锋，康建省，李涛，等.腹腔镜脾切除术治疗115例免疫性血小板减少症的疗效分析［J］.重庆医学，2014，43（10）：1199-1200.
［6］	Stotler BA，Schwartz J.How we use WinRho in patientswith idiopathic thrombocytopenic purpura［J］.Transfusion，2016，55（11）：2547-2550.
［7］	艾尔肯·阿皮孜，孙培春.腹腔镜脾切除术治疗免疫性血小板减少性紫癜的回顾性研究［J］.医药论坛杂志，2015，36（9）：93-94.
［8］	闫慧明，贾彬，张平.难治性特发性血小板减少型紫癜脾切除的临床分析［J］.中国普通外科杂志，2012，21（6）：700-703.
［9］	王春荣.腹腔镜下脾切除术治疗46例特发性血小板减少性紫瘫的临床疗效观察［J］.贵州医药，2014，38（10）：891-892.［10］Rijcken E，Mees ST，Bisping G，et al.Laparoscopic splenectomy for medically refractory immune thrombocytopenia （ITP）：a retrospective cohort study on longtime response predicting factors based on consensus criteria［J］.Int J Surg，2014，12（12）：1428-1433.
［11］	Martin Arnau B，Turrado Rodriguez V，Tartaglia E，et al. Impact of preoperative platelet count on perioperative outcome after laparoscopic splenectomy for idiopathic thrombocytopenic purpura［J］.Cir Esp，2016，94（7）：399-403.
［12］	侍阳，宋庆伟，于生才，等.腹腔镜脾切除术治疗难治性血小板减少性紫癜的临床应用［J］.腹腔镜外科杂志，2014，19（5）：356-358.
［13］	曹卫刚，邱宝安.腹腔镜脾切除治疗特发性血小板减少性紫瘫九例体会［J］.中华普外科手术学杂志（电子版），2014，8（2）：168-170.
［14］	Seong RH.Rapidly calcified all of multiple intracranial hemorrhages occurred in a patient with chronic idiopathic thrombocytopenic purpura［J］.Interdisciplinary Neurosurg，2016，3（5）：1024-0129.
［15］	Tsai CH，Bussel JB，Imahiyerobo AA，et al.Platelet count control in immune thrombocytopenic purpura patient：optimum romiplostim dose profile［J］.J Process Control，2016，45（45）：1147-1151.