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2020 Vol. 27, No. 24
Published: 2020-08-28
4
SWOT analysis and development strategy for non-drug health-maintaining methods facing extinction in ancient books under the background of new times
TONG Lin1 LI Hong-tao1 LI Bing1 ZHANG Wei-na1 ZHANGHua-min2▲
Lots of health-maintaining methods have been recorded in ancient books of traditional Chinese medicine,many of which have been inherited and contributed to disease control and prevention in history.However,due to the particularity of ancient books,many other efficacious health-maintaining knowledge and methods remain undiscovered and are in danger of extinction.This article adopts the SWOT analysis method to deeply analyze the advantages,disadvantages,opportunities and challenges of non-drug health-maintaining methods in ancient books under the background of the new era.The results show that the future development of non-drug health-maintaining methods that are in danger of extinction will coexist with opportunities and challenges.Advantages should be used and disadvantages should be avoided under the guidance of national policies,to explore cultural connotations,strive for the protection of intangible cultural heritage,and realize multi-dimensional rescue,sorting,excavation and practice of health-maintaining methods on the basis of scientific evaluation,give full play to characteristic functional advantages,and combine the characteristics of the times,innovate and compile non-drug health-maintaining methods facing extinction,develop and expand the mass base,and strengthen scientific research,professional publicity and promotion.
2020 Vol. 27 (24): 4-8 [
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40
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9
Effect of Ethamsylate on the enzymatic detection of serum creatinine
JING Hang1 NIU Zhi-jie1 LIU Zi-yan1 LIU Lin2 CHEN Sheng-chao3 WU Hong-quan1▲
Objective
To investigate the effect of Ethamsylate on the enzymatic detection of serum creatinine(CREA).
Methods
Fresh serum was collected from patients who came to Guizhou Provincial People′s Hospital in October 2019 and prepared the collected serum to be high and low concentrations of CREA mixed serum.The interference screening experiments and dose-effect experiments were conducted on enzymatic detection of serum CREA according to the EP7-A2 document developed by the Clinical and Laboratory Standards Institute(CLSI).Then the interfering results at different concentrations were used to determine the effect of Ethamsylate on detection of CREA.
Results
Interference screening experiment：the average value of the experimental group sample was 166.28μmol/L,and that of the control group was 403.44μmol/L.The interference value (d
abs
)95%
CI
of the experimental group was(-237.16±1.82)μmol/L,indicated the lowest offline value of the d
abs
95%
CI
was greater than the acceptable standard(d
max
)of the preset interference experiment.Dose-effect experiment：the regression curve equation of interference effect of enzymatic on low value CREA samples was
Y
=-1.727e-6
X
3
+0.0016
X
2
-0.474
X
-5.285(
F
=406.080,
R
2
=0.981,
P
=0.000),when the concentration of ethamsylate was below 1.174 mg/L,the d
abs
was lower than the d
max
for interference experiment.Meanwhile,the regression curve equation of Ethamsylate for high value CREA samples was
Y
=-5.105e-6
X
3
+0.00499
X
2
-1.632
X
-11.252(
F
=1483.642,
R
2
=0.995，
P
=0.000),and the d
abs
was lower than the d
max
when the concentration of Ethamsylate was below 9.727 mg/L.
Conclusion
Ethamsylate causes the negative interference on the serum CREA detection by enzymatic method which may be attribute to the factors of detection principle.It is suggest to consult the patients whether to take Ethamsylate drug,redraw blood after discontinuation of the drug,or use other principles of CREA assay to check if necessary.Meanwhile,this study also provides some references for the accurate analysis of CREA.
2020 Vol. 27 (24): 9-12 [
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35
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13
Analysis of the composition and homology of non-single urinary stones in vivo by CT energy spectrum
FU Xiao-bin1 HUANGZhou1▲ CUI Yun-neng2 LIN Wei-guang3 HE Jian1
Objective
To use CT energy spectrum to explore the
in vivo
stone composition of patients with non-single urinary stones,and to conduct homology analysis.
Methods
A total of 102 cases were collected from June 2018 to December 2019 who went to Foshan Sanshui District People′s Hospital for urinary system CT energy spectrum analysis and scanning of stones,and all cases were detected by infrared spectroscopy.Divide the same patient′s urinary tract stones into 7 types according to the stone location：ipsilateral kidney,opposite kidney,ipsilateral kidney ureter,opposite kidney ureter,opposite ureter,bladder,and bladder+kidney/ureter.Energy spectrum stone analysis software was used to measure average effective atomic number,peak value of effective atomic number,50 keV single energy CT value,calcium to water ratio,slope of energy spectrum attenuation curve,140 kVp mixed energy CT value,and determine the stone composition;the same patient in the same body stone composition was judged as homology,otherwise it was heterogeneity.
Results
A total of 204 stones were analyzed by CT energy spectrum of 102 patients,and the coincidence rate of
in vivo
energy spectrum and infrared spectrometer was 85.3%.The results of determining stone composition were calcium phosphate (51 stones),calcium oxalate(85 stones),struvite(25 stones),cystine(6 stones),uric acid(23 stones)and mixed(14 stones).Comparison of the average effective atomic number,peak value of effective atomic number,50 keV single energy CT value,calcium to water ratio,slope of energy spectrum attenuation curve,and 140 kVp mixed energy CT value of the five single-component stones,the differences were statistically significant(
P
＜0.01).Patients with homology accounted for 75.5%,mainly bladder and ipsilateral kidney ureter.The 7 types of homology from large to small are bladder,ipsilateral kidney ureter,opposite kidney,ipsilateral kidney,opposite ureter,opposite kidney ureter,bladder+kidney/ureter.
Conclusion
CT energy spectrum imaging can more accurately analyze the components of urinary stones
in vivo
.The components of non-single urinary stones in the same patient have high homology,especially the bladder and ipsilateral kidney ureter.
2020 Vol. 27 (24): 13-16 [
Abstract
] (
37
)
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17
Clinical effect of Sofren Injection in the treatment of patients with advanced non-small cell lung cancer
ZHOU Xiao-long1 CHENG Wen-na1 ZHANGJing-yi2▲
Objective
To explore the clinical effect of Sofren Injection in the treatment of patients with advanced nonsmall cell lung cancer(NSCLC).
Methods
A total of 120 patients with advanced NSCLC admitted to the Binzhou Medical University Hospital from January to December 2018 were selected as study subjects,and were divided into the control group and the treatment group by the random number table method,with 60 patients in each group.All patients were divided into control group and treatment group by the random number table method,with 60 patients in each group.The control group was given Compound Sophora Flavescens Injection and symptomatic treatment,and the treatment group was given Sofren Injection on this basis.The levels of serum tumor markers,traditional Chinese medicine symptom scores and immune function indexes before and after treatment were compared between the two groups.The short-term efficacy was compared between the two groups.Quality of life scores before and after treatment were compared between the two groups.
Results
The levels of carcinoembryonic antigen (CEA),cytokeratin 19 fragment(CYFRA21-1),carbohydrate antigen 19-9(CA19-9),and neuron-specific enolase(NSE)in the two groups were lower than those before treatment,with statistically significant differences (
P
＜0.05).After treatment,CEA,CYFRA21-1,CA19-9 and NSE in the treatment group were all lower than those in the control group,with statistically significant differences (
P
＜0.05).The scores of traditional Chinese medicine symptoms of cough and expectoration of sputum,chest congestion and shortness of breath,abdominal distension and stupor,nausea and vomiting,and limb weakness in the two groups after treatment were lower than those before treatment,and the differences were statistically significant(
P
＜0.05).The scores of traditional Chinese medicine symptoms of cough and expectoration of sputum,chest congestion and shortness of breath,abdominal distension and stupor,nausea and vomiting,and limb weakness in the treatment group were lower than those in the control group,with statistically significant differences(
P
＜0.05).The total effective rate and stability of the treatment group were higher than those of the control group,and the differences were statistically significant(
P
＜0.05).The total effective rate and stability of the treatment group were higher than those of the control group,and the difference was statistically significant(
P
＜0.05).After treatment,CD4
+
and CD4
+
/CD8
+
in the two groups were higher than those before treatment,and CD8
+
was lower than that before treatment,with statistically significant differences (
P
＜0.05).After treatment,CD4
+
and CD4
+
/CD8
+
in the treatment group were higher than those in the control group,and CD8
+
was lower than that in the control group,with statistically significant differences(
P
＜0.05).The scores of dyspnea,anorexia,cough,hemoptysis and pain in the treatment group were lower than those in the control group,and the differences were statistically significant(
P
＜0.05).
Conclusion
Sofren Injection can significantly alleviate traditional Chinese medicine symptoms of patients with advanced NSCLC,and significantly improve the clinical treatment effect of patients with intermediate and advanced lung cancer,it can improve the immune function,and improve the clinical symptoms.It is worthy of clinical application.
2020 Vol. 27 (24): 17-21转26 [
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] (
41
)
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22
Value of nasoenteric tube in improving nutritional status and long-term prognosis of patients with artificial airway
WANGXing-ling KONGXiao-hong HUANGBao-qin ZHONGYou-di
Objective
To investigate the value and long-term prognosis of the patients with artificial airways treated with nasoenteric tube combined with nutrient pump infusion.
Methods
From January 1
st
,2018 to March 31
st
,2020,100 patients with artificial airway were selected as subjects.According to the method of random sampling,they were divided into observation group(50 cases)and control group(50 cases).At the observation group,the nasogastric tube was placed by bedside with bare hands,and all of them were located below the X line to reach the pylorus(duodenum or upper jejunum).The patients in control groups were placed into the nasogastric tube.Both groups were treated with nutrition pump and infusion of nutrient solution through feeding tube for 30 days.Serum albumin(ALB),body mass index(BMI),triceps skin fold thickness(TSF),mechanical ventilation duration,incidence of aspiration pneumonia,withdrawal rate,successful tube sealing rate after tracheotomy,and gastrointestinal intolerance were compared between the two groups.
Results
The ALB,BMI,TSF,withdrawal rate and the successful sealing rate after tracheotomy in the observation group were higher than those in the control group,and the differences were statistically significant(
P
＜0.05).The duration of mechanical ventilation in observation group was shorter than that in control group,incidence of aspiration pneumonia and gastrointestinal intolerance in the observation group were lower than those in the control group,and the differences were statistically significant(
P
＜0.05).
Conclusion
The implantation of bare-handed nasoenteric tube and the infusion of nutrition pump can improve the nutritional status of patients with artificial airway,shorten mechanical ventilation,reduce the incidence of aspiration pneumonia,increase removal rate and seal rate of trachea after,and improve gastrointestinal tolerance,it can improve the long-term prognosis of patients with artificial airway to some extent.
2020 Vol. 27 (24): 22-26 [
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] (
38
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27
Meta-analysisof effect comparison of Paliperidone Sustained-release Tablets and Aripiprazole in the treatment of schizophrenia
LI Yan1 BA Wen-qiang2 YUAN Ye-feng3▲
Objective
To compare the effect and adverse reactions of Paliperidone Sustained-release Tablets and Aripiprazole in the treatment of schizophrenia by Meta-analysis.
Methods
Randomized controlled trials(RCTs)related to the Paliperidone Sustained-release Tablets and Aripiprazole in the treatment of patients with schizophrenia were searched in China National Knowledge Infrastructure,Wanfang,Weipu Database,Chinese Biomedical Literature Service System,PubMed,Embase,Cochrane Library databases.Search time was from the establishment of the database to October 2019.Meta-analysis was carried out with RevMan 5.3 software.
Results
Finally,a total of 22 RCTs literatures were included.Meta-analysis showed that compared with the Aripiprazole group,the reduction of total score of positive and negative symptoms scale (PANSS)in the Paliperidone Sustained-release Tablets group was better after 2 and 4 weeksof treatment,and the differences were statistically significant(after 2 weeks of treatment：
MD
=-8.43,95%
CI
[-14.61,-2.26],
P
=0.007;after 4 weeks of treatment：
MD
=-5.23,95%
CI
[-9.57,-0.89],
P
=0.02).After 8 weeks of treatment,there were no significant differences in the PANSSscore(
MD
=-5.47,95%
CI
[-11.31,-0.38],
P
=0.07),positive symptoms score(
MD
=-2.49,95%
CI
[-7.33,2.34],
P
=0.31),and the general psychotic symptoms score(
MD
=-1.43,95%
CI
[-5.99,3.12],
P
=0.54)between the two groups.Compared with Aripiprazole group,the reduction of negative symptoms score of Paliperidone Sustained-release Tablets group was better,and the difference was statistically significant(
MD
=-1.18,95%
CI
[-2.10,-0.26],
P
=0.01).The prolactin level in the Paliperidone Sustained-release Tablets group was higher than that in the Aripiprazole group,and the difference was statistically significant(
MD
=31.39,95%
CI
[13.62,49.15],
P
=0.0005).There was no significant difference in the incidence of adverse reactions between the two groups of patients(
P
＞0.05).
Conclusion
Paliperidone Sustained-release Tablets are as effective as Aripiprazole in the treatment of schizophrenia.However,it has faster onset and much better effect for the negative symptoms.The incidence of adverse reactions between the two drugs is similar,but Paliperidone Sustained-release Tablets can increase the serum prolactin level of patients.
2020 Vol. 27 (24): 27-32 [
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] (
40
)
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33
Research advance on the inhibitory effect of food,Chinese herbal medicine and its active ingredients on CYP2C8
ZHANG Qi-yue YANG Chang-qing▲
Cytochrome P4502C8 (CYP2C8)is an important part of the human CYPenzyme system (CYP450s)and is involved in the metabolism of many commonly used clinical drugs.The number of reported CYP2C8 enzyme inhibitors is increasing,and the research on the inhibitory effect of Chinese medicine preparations and food on CYP2C8 is also gradually deepened for Chinese medicine and its active ingredients.By analyzing and summarizing through referring to relevant literature in recent years at home and abroad,the research progress on the inhibition of CYP2C8 by food,Chinese herbal medicines,and their active ingredients both at home and abroad was reviewed.Attention should be paid to the study of drug-drug interaction caused by inhibition effects of Chinese herbal medicines,their active ingredients,and food in combination with other CYP2C8 substrates to promote the rational use of drugs and prevent the occurrence of adverse drug reactions related to Chinese medicine-Western medicine interaction and food-drug interaction.
2020 Vol. 27 (24): 33-36 [
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39
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37
Research advances in the application of intravenous anesthesia with spontaneous breath in surgery
WU Chun-feng1 HUANG Wei-qin2 YING Jian-xin1 QU Wei1▲
Intravenous anesthesia with spontaneous breath is widely used in the surgical field due to its minimally invasive nature and advantages in enhanced recovery after surgery(ERAS).Most operations that require general anesthesia with endotracheal intubation can be performed under this anesthesia.However,previous literature is rarely reported on the pathophysiology and airway management of intravenous anesthesia with spontaneous breath.This paper compares intravenous anesthesia with spontaneous with traditional endotracheal intubation anesthesia from the aspects of pathophysiology,specific anesthesia management,exclusion or suition population,learning curve and ERAS to illustrate its feasibility,safety and advantages in ERAS,and thus demonstrates that it can be widely used in clinic under the condition of active preparation.
2020 Vol. 27 (24): 37-40 [
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39
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41
Analysis of related substances in Difenidol Hydrochloride Tablets
CHEN Min-min TANG Xiao-peng WU Ze-jun LIU Shui-ping▲ WANG Xi
Objective
To evaluate the consistency of related substances between the domestically marketed Difenidol Hydrochloride Tablets and reference preparations.
Methods
The related substances of Difenidol Hydrochloride Tablets were determined and evaluated according to the official quality standard recorded in
Pharmacopoeia of the People
′
s Republic
(2015 edition,version 2).The forced degradation test was also carried out.
Results
The detection limit of impurityⅠwas 2.8 ng,and the quantitative limit was 9.7 ng.The solution of Difenidol Hydrochloride was stable in 18 hours,and the relative standard deviation (
RSD
)of impurities and main peak area was less than 2%.The linearity range of impurityⅠwas 0.4829-48.2900μg/ml(
R
2
=1).In the precision test of impurityⅠ,the
RSD
of peak area was 4.2%(
n
=12).The average recovery of impurityⅠ(
n
=6)was 102.6%,and
RSD
was 2.0%.No impurities were detected in two batch tablets of the first domestic manufacturer.The content of impuritiesⅠwas 0.14%in another batch.No impurities were detected in two batch tablets of the original manufacturer.The content of impuritiesⅠwas 0.10%in another batch.The content of impuritiesⅠwas among 0.2%-0.5%in the other three domestic manufacturers′tablets.Under the conditions of light,oxidation,heat and alkaline damage,there was no significant change in the related substances between the first domestic imitator and the original manufacturer′s tablets.Under the acid damage condition,the degradation of the main peak was 15%,and the increase of impurityⅠwas 15%.
Conclusion
Impurity profiling of the first generic preparations is consistent with the reference preparations.For other three domestic manufacturers,impurityⅠcontent is 2-5 times higher than that of the reference preparations.
2020 Vol. 27 (24): 41-45 [
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] (
34
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46
Simultaneous determination of three components in Shengmaiyin by HPLC
WANG Yong-hong1 YUAN Huan-huan2 WANG Xue-Ying2▲
Objective
To establish a high performance liquid chromatography (HPLC)method for the simultaneous determination on the components of schizandrin A,deoxyschizandrin,schizandrin B in Shengmaiyin.
Methods
An Agilent Eclipse Plus C
18
(250 mm×4.6 mm,5μm)column was used,methanol-water(72∶28)was used as the mobile phase,the column temperature was 30°C,the detection wavelength was 254 nm,and the flow rate was 1.0 ml/min.
Results
The sample size of schisandrin A,deoxyschizandrin,and schisandrin B showed a good linear relationship within the range of 0.5975-9.5600μg (
r
=0.9999),0.0750-1.199μg (
r
=0.9998),and 0.1888-3.0210μg (
r
=0.9999),with good precision,stability,and repeatability,the average recovery rate of sample addition was 99.3%,98.9%,98.6%,and the
RSD
was 0.9%,1.5%,1.2%,respectively.The contents of schisandrin A,deoxyschizandrin,and schisandrin B in 5 batches of Shengmaiyin samples from Tiancheng Pharmaceutical Co.,Ltd.were determined,and the results were stable.
Conclusion
This method is simple,accurate,simple and stable,and can be used for the determination of schisandrin A,deoxyschizandrin and schisandrin B in Shengmaiyin.
2020 Vol. 27 (24): 46-48转52 [
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] (
43
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49
Clinical effect of external application of traditional Chinese medicine combined with phaseⅠeradication operation in the treatment of perianal abscess
XIA Lv-chi
Objective
To explore the clinical effect of external application of traditional Chinese medicine combined with phaseⅠeradication operation in the treatment of perianal abscess.
Methods
A total of 88 patients with perianal abscess admitted to our hospital from October 2018 to October 2019 were selected and divided into two groups according to the random number table method,44 cases in each group.All patients were treated with phaseⅠeradication operation,and the control group was treated with routine treatment.On this basis,the study group was treated with external application of traditional Chinese medicine until wound healing.Two weeks after operation,the clinical effect,laboratory index and rehabilitation effect of the two groups were compared.
Results
The total effective rate of the study group(97.73%)was higher than that of the control group(81.82%),the difference was statistically significant(
P
＜0.05).There was no significant difference between the two groups on the same day after operation in the level of laboratory indicators(
P
＞0.05);Interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)2 weeks after operation in study group were（17.96±5.92）,（94.93±17.42）ng/L,lower than those in the control group of(22.05±7.38),(106.46±19.21)ng/L,vascular endothelial growth factor(VEGE)was(4.38±0.62)ng/L,higher than that in the control group of(3.59±0.53)ng/L,the differences were statistically significant(
P
＜0.05).The duration of postoperative pain,wound healing time and hospitalization time in the study group were(2.38±0.71),(17.94±2.77),(10.24±2.25)d,shorter than those in the control group of(3.62±0.75),(21.83±3.59),(12.24±2.63)d,and the differences were statistically significant(
P
＜0.05).
Conclusion
External application of traditional Chinese medicine combined with phaseⅠeradication surgery is effective in the treatment of perianal abscess,which can improve the level of inflammatory factors and growth factors,and enhance the rehabilitation effect.
2020 Vol. 27 (24): 49-52 [
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] (
37
)
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53
Value of red blood cell distribution width in the prediction of death of severe pancreatitis at different ages
LIU Zeng-yong LIN Min DENG Wen YU Jing-gui CHEN Lu
Objective
To investigate the value of red blood cell distribution width (RDW)in the prediction of death of severe pancreatitis (SP)at different ages.
Methods
The retrospective analysis was performed,and the clinical data of 100 patients with SPin our hospital from January 2018 to December 2019 were selected.They were divided into 27 cases of youth group (18-34 years old),57 cases of middle-aged group (＞34-59 years old)and 16 cases of elderly group(＞59 years old)according to different ages.The RDW levels and death rate were compared among the three groups,and the value of RDW in the prediction of death of SPat different ages was analyzed.
Results
The RDW level in elderly group was higher than that in middle-aged group and youth group,and the RDW level in middle-aged group was higher than that in youth group,with statistical differences (
P
＜0.05).There was statistical difference in the death rate among the three groups(
P
＜0.05).The death rate in elderly group and middle-aged group was higher than that in youth group(
P
＜0.05).The results of ROC curve showed that the area under the curve of RDW in predicting the death of SPat different ages was 0.720,which had certain predictive value.
Conclusion
RDW has certain predictive value for the death of SP at different ages.As the patient′s age increases,the higher the RDW level,the worse the prognosis of the patient,which can provide an important basis for clinical diagnosis and treatment.
2020 Vol. 27 (24): 53-55 [
Abstract
] (
45
)
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56
Comparison of changes of pulmonary function in different ages of patients with chronic obstructive pulmonary disease after smoking cessation
LIU Jing-hu YUAN Shui-sheng HU Ping-sheng ZOU Xiao-fan FAN Jia-liang
Objective
To investigate the changes of pulmonary function in different ages of patients with chronic obstructive pulmonary disease (COPD)after smoking cessation.
Methods
The clinical data of 60 patients with COPD admitted to our hospital from February 2018 to February 2019 were retrospectively collected.All patients were divided into three groups according to the age of patients,18-38 years old was taken as youth group,＞38-59 years old was taken as middle-aged group,and＞59 years old was taken as senile group,20 cases in each group.All selected cases were given smoking cessation intervention,and the pulmonary function (slow vital capacity [SVC],forced vital capacity of percentage prediction [FVC%Pred],forced expiratory volume in one second of percentage prediction [FEV
1
%Pred],forced expiratory volume in one second/forced vital capacity[FEV
1
/FVC%])and quality of life(nottingham health profile[NHP]）were compared among the three groups before and after smoking cessation.
Results
After smoking cessation for 12 months,the levels of pulmonary function indexes such as SVC,FVC%Pred,FEV
1
%Pred and FEV
1
/FVC in the three groups were higher than those before smoking cessation,and youth group was higher than middle-aged group and senile group,and the differences were statistically significant(
P
＜0.05).The NHPscore of youth group was higher than that of middle-aged group and senile group,and middle-aged group was higher than that of the senile group,and the differences were statistically significant(
P
＜0.05).
Conclusion
Smoking cessation intervention for different ages of patients with COPD has certain effect,it can improve pulmonary function,prevent and control the diseases.At the same time,patients should be encouraged to early quit smoking to effectively improve their quality of life.
2020 Vol. 27 (24): 56-58 [
Abstract
] (
38
)
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59
Clinical effect of Entecavir combined with Adefovir Dipivoxil in the treatment of chronic hepatitis B
WANGYan-yan
Objective
To explore the clinical effect of Entecavir and Adefovir Dipivoxil in the treatment of chronic hepatitis B.
Methods
A total of 60 patients with chronic hepatitis B who were admitted to our hospital from February 2018 to February 2019 were selected as the research objects.and they were divided into observation group (odd number patients)and control group (even number patients)using the single and double number method,30 cases in each group.Patients in the control group were treated with Adefovir Dipivoxil,and patients in the observation group were treated with Entecavir combined with Adefovir Dipivoxil.The levels of total bilirubin (TBil),alanine aminotransferase(ALT)and albumin(ALB),the total effective rate of clinical treatment,and the total incidence of adverse reactions were compared between the two groups of patients before and after treatment.
Results
There were no significant differences in TBil,ALT and ALB between the two groups before treatment(
P
＞0.05).After treatment,the levels of TBil and ALT in the observation group were lower than those in the control group,while the level of ALB was higher than that in the control group,with statistically significant differences (
P
＜0.05).The total effective rate of the test group was 93.00%,higher than that of the control group(70.00%),and the difference was statistically significant(
P
＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(
P
＜0.05).
Conclusion
Entecavir combined with Adefovir Dipivoxil in the treatment of chronic hepatitis B can effectively improve the level of TBil,ALT and ALB,and increase the total effective rate of clinical treatment.and reduce the incidence of adverse reactions.It is worthy of clinical application
2020 Vol. 27 (24): 59-61 [
Abstract
] (
41
)
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12
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62
Application effect of Petrolatum gauze block combined with Vitamin B
12
Mixture Solution in dressing change for second-degree radiation skin injury
12 Mixture Solution in dressing change for second-degree radiation skin injury[J]. 中国当代医药, 2020,27(24): 62-65')" href="#">
LIU Xiao-yun WEN Sheng-ying ZENG Ying-ting
Objective
To explore the application effect of Petrolatum gauze block combined with Vitamin B
12
Mixture Solution in dressing change for second-degree radiation skin injury.
Methods
From January to November 2019,90 patients with second-degree radiation skin injury caused by intensity-modulated radiotherapy were selected as subjects and divided into control group and observation group by random number table method,with 45 cases in each group.The control group used sterile gauze block soaked with Vitamin B
12
Mixture Solution for wet compress,and the observation group was added with Petrolatum gauze block on the basis of the control group.The clinical efficacy,pain scores,and epidermal cytokine(vascular endothelial growth factor[VEGF],transforming growth factor-β[TGF-β
1
],basic fibroblast growth factor[bFGF])levels before and after treatment were compared between the two groups of patients after treatment]expression.
Results
After treatment,the total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(
P
＜0.05).After treatment for 15 and 30 minutes,the numerical grading method (NRS)pain score of the observation group was lower than that of the control group,the difference was statistically significant(
P
＜0.05).After treatment for 3 days,the levels of VEGF,TGF-β
1
and bFGF in the observation group were all higher than those in the control group,with statistically significant differences(
P
＜0.05).
Conclusion
Petrolatum gauze block combined with Vitamin B
12
Mixture Solution has a good application effect in the second-degree radiation skin injury dressing change,which can effectively relieve the pain of patients,promote skin tissue recovery,and regulate the expression of epidermal cytokines.
2020 Vol. 27 (24): 62-65 [
Abstract
] (
37
)
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14
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66
Application effect of self-made metal ring fixed disposable injector empty tube containing sputum suction connecting tube device in patients in respiratory intensive care unit
ZENG Gui-hua
Objective
To investigate the application effect of self-made metal ring fixed disposable injector with sputum suction connecting device in respiratory intensive care unit(RICU).
Methods
A total of 72 severe cases of RICU in our hospital from January to December 2018 were selected as the study objects,and divided into the observation group and the control group according to random number table method,36 cases in each group.The time of sputum aspiration,total number of colonies at the connecting tube and sputum aspiration effect were compared between the two groups.
Results
The time of sputum aspiration in the observation group was shorter than that in the control group,and the difference was statistically significant(
P
＜0.05).The total number of colonies at the junction tube in the observation group was fewer than that in the control group,and the difference was statistically significant(
P
＜0.05).The effective rate of sputum suction in the observation group was higher than that in the control group,the difference was statistically significant(
P
＜0.05).
Conclusion
Self-made metal ring fixed disposable syringe empty tube to hold sputum suction connection devicis is easy to use,sputum suction connection is fast,with beautiful appearance and convenient cleaning,not easy to hide dirt.
2020 Vol. 27 (24): 66-68 [
Abstract
] (
39
)
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8
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69
Effect analysis of Bacillus Cereus Live Bacteria Tablets in the adjuvant drug therapy of pregnant patients with acute diarrhea
ZHANG Zi-cheng1 QIU Wen-fang1 DAI Juan2 CHEN Ya-li1 LIFang-ji1 LIU Ju-ying1
Objective
To explore the clinical effect of Bacillus Cereus Live Bacteria Tablets in the adjuvant drug therapy of pregnancy patients with acute diarrhea.
Methods
A total of 60 pregnant women with acute diarrhea treated in the Department of Internal Medicine of Ganzhou Maternal and Child Health Hospital from November 2018 to October 2019 were selected as the research objects,and they were divided into control group(30 cases)and study group(30 cases)by random comprehensive balance method.The patients in the control group were treated with Montmorillonite Powder and the patients in the study group were treated with Montmorillonite Powder combined Bacillus Cereus Live Bacteria Tablets.Patients in both groups were treated for 5 d.The clinical efficacy,number of feces,symptom disappearance time and total adverse reaction rate of the two groups were compared.
Results
The total effective rate of clinical treatment in the study group was higher than that in the control group,the number of feces in the study group was less than that in the control group,the time of vomiting,abdominal pain disappearance and normal fecal routine time in the study group were shorter than those in the control group,the differences were statistically significant(
P
＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (
P
＞0.05).
Conclusion
According to the symptoms of pregnancy combined with acute diarrhea,the application of Bacillus Cereus Live Bacteria Tablets combined with Montmorillonite powder has a significant clinical effect,which can not only reduce the frequency of defecation,but also shorten the time of vomiting,abdominal pain disappearance and fecal routine time,strong security,which is worth popularizing.
2020 Vol. 27 (24): 69-71转75 [
Abstract
] (
34
)
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10
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72
Effect of checklist management on patients with mechanical ventilation
LIANGDe-jian HUANGRu-wen ZHU Jiang-fei JIANGYong DENGGuang-jin ZHU Ya-rong XIAORen-wei
Objective
To explore the effect of self-designed checklist on the prognosis of patients with mechanical ventilation.
Methods
From July 2018 to March 2020,all patients with mechanical ventilation were selected as the study subjects.According to the time period,the study group selected 204 patients with mechanical ventilation from July 2019 to March 2020,and the control group selected 204 patients with mechanical ventilation from July 2018 to March 2019.The patients in the study group were treated with mechanical ventilation according to the treatment process of mechanical ventilation in the department,and the daily three-level doctor rounds to guide the management.By designing the checklists of mechanical ventilation treatment,checklists were used to manage the treatment process of patients with mechanical ventilation.In the control group,patients were treated with mechanical ventilation according to the treatment process of mechanical ventilation in the department,and the daily three-level doctor rounds for guidance and management,but the checklist management was not used.The differences of mechanical ventilation time,ICU hospitalization time,incidence of ventilator-associated pneumonia (VAP),reintubation rate 48 h after tracheal intubation and extubation,and mortality between the two groups were compared.
Results
The mechanical ventilation time and ICU hospitalization time in the study group were shorter than those in the control group,the differences were statistically significant(
P
＜0.05);the incidence of VAPand the rate of reintubation 48 h after extubation were lower than those in the control group,the differences were statistically significant(
P
＜0.05);the mortality showed no statistically significant difference in the two groups (
P
＞0.05).
Conclusion
The self-designed mechanical ventilation treatment checklist can shorten the time of mechanical ventilation and ICU hospitalization,reduce the incidence of VAPand the rate of reintubation 48 h after extubation,ensure the safety of patients,it is worth popularizing.
2020 Vol. 27 (24): 72-75 [
Abstract
] (
41
)
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76
Study on construction strategy and practice of Corona Virus Disease 2019 prevention and control system for pregnant women
CHEN Guo-qing LIBin WU Xiao-xia LI Jun ZHOU Chan CHEN Li-hua LI Zhi-quan NIU Jian-min▲
Objective
To establish and practice Corona Virus Disease 2019 prevention and control system for pregnant women.
Methods
The data were collected from the Obstetrics Department of Shenzhen Maternal and Child Health Hospital Affiliated to Southern Medical University from February 1 to March 31,2020.A Corona Virus Disease 2019 infection control area was established,and the prevention and control system of Corona Virus Disease 2019 in pregnancy was formulated and improved.The prevention and control process were established,and the prevention and control training team were established,and the protection and isolation disinfection mechanism was formulated.
Results
Corona Virus Disease 2019 pneumonia prevention and control system for pregnant women was successfully established,and the prevention and control system of new pregnancy coronavirus infection prevention and control area,obstetric fever clinic,isolation delivery room,isolation operation room and isolation ICU ward were set up separately.The system and process were perfect,the first pass rate of medical staff training was 96.06%,and the smooth operation of Corona Virus Disease 2019 prevention and control system for pregnant women was guaranteed.
Conclusion
Corona Virus Disease 2019 prevention and control system for pregnant women during epidemic period is beneficial to the investigation of suspicious pregnant women with Corona Virus Disease 2019 and the normal treatment needs of ordinary pregnant women,which can fully protect the safety of pregnant women.
2020 Vol. 27 (24): 76-79 [
Abstract
] (
44
)
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14
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80
Application of self-made U-shaped ice sandbag in patients with head and neck surgery
QIU Xiao-ling LI Gang XIAO Yan CHEN Yi-zhao
Objective
To explore the effect of self-made U-shaped ice sandbag in patients with head and neck surgery.
Methods
A total of 50 patients undergoing head and neck surgery in our hospital from July 2018 to December 2019 were selected.They were divided into two groups with 25 cases in each group according to random number table method.The control group used a salt bag to fix the operation site after the operation,and the experimental group used a self-made U-shaped ice sand bag to fix the operation site after the operation.The degree of dysphagia,local tissue swelling,pain,satisfaction,the stability,fitness,comfort and adjustability of salt bag and self-made U-shaped ice sandbag were observed.
Results
The degree of dysphagia,pain and local tissue swelling in the experimental group was lighter than that in the control group,and the total satisfaction was higher than that in the control group with statistical significances(
P
＜0.05).The ratios of the experimental group with stability,fit,comfort and adjustability were all higher than those of the control group,and the differences were statistically significant(
P
＜0.05).
Conclusion
The application of self-made U-shaped ice sandbag in patients with head and neck surgery obtains a good effect.It can not only reduce the difficulty in swallowing,pain and local tissue swelling,but also improve the stability,fitness,comfort,adjustability and patient′s satisfaction.
2020 Vol. 27 (24): 80-82 [
Abstract
] (
38
)
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12
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83
Early diagnostic value of high-sensitive troponin T combined with fragmented QRScomplex in acute myocardial infarction
MENG Jin-feng LEI Jin-hua JIN Rui-mian CHEN Fu-ming
Objective
To investigate the early diagnostic value of high-sensitive troponin T(hs-TnT)combined with fragmented QRScomplex in acute myocardial infarction(AMI).
Methods
A total of 102 cases of AMI(AMI group)admitted to our department of cardiology and 78 cases of healthy examinees(control group)were selected from October 2017 to October 2018 in our hospital.The serum hs-TnT level and the incidence of fragmented QRScomplex were compared between the two groups,as well as between ST-segment elevation myocardial infarction patients(STEMI group,
n
=69)and non-ST-segment elevation myocardial infarction patients(NSTEMI group,
n
=33).Then the diagnostic efficacy of single detection and combined detection of serum hs-TnT level and fragmented QRScomplex in the diagnosis of the AMI were compared.
Results
The level of serum hs-TnT in AMI group was higher than that in control group(
P
＜0.05).The level of serum hs-TnT in STEMI group was higher than that in NSTEMI group in AMI group (
P
＜0.05).The incidence of fragmented QRScomplex in the AMI group was higher than that of the control group(
P
＜0.05).The incidence of the fragmented QRScomplex of STEMI group in the AMI group was higher than that of the NSTEMI group(
P
＜0.05).The diagnostic efficiency of hs-TnT combined with ECG fragmented QRS complex was better than that of hs-TnT and ECG fragmented QRScomplex alone(
P
＜0.05).
Conclusion
For the early diagnosis of acute myocardial infarction,the combined detection of hs-TnT and electrocardiogram fragmentation QRS wave has higher sensitivity and accuracy than that of single detection,and can provide valuable reference information for clinical diagnosis and treatment of AMI.
2020 Vol. 27 (24): 83-86 [
Abstract
] (
41
)
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11
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87
Clinical effect of Octreotide combined with Omeprazole in the treatment of liver cirrhosis complicated with upper gastrointestinal bleeding
HU Qing-fang1 LIU Na1 XU Hong1 LI Jing-hua2
Objective
To investigate the clinical effect of Octreotide combined with Omeprazole in the treatment of cirrhosis complicated with upper gastrointestinal hemorrhage.
Methods
A total of 60 patients with cirrhosis complicated with upper gastrointestinal bleeding admitted to our hospital from September 2015 to April 2019 were selected as study subjects,and were divided into control group (30 cases)and experimental group (30 cases)according to the random number table method.Patients in the two groups were given routine symptomatic treatment,on the basis of which the control group was treated with Omeprazole alone,while the experimental group was treated with Octreotide combined with Omeprazole.The treatment course was 1 week in both groups.After the course of treatment,the overall effective rate,hemostasis time,rebleeding rate,hospitalization time and the improvement of inflammatory factors in the two groups were observed and compared,and the total incidence of adverse reactions during treatment was recorded.
Results
After treatment,the overall effective rate of the experimental group was 96.67%,which was higher than that of the control group(66.67%),and the difference was statistically significant(
P
＜0.05).The hemostasis time and hospital stay in the experimental group were shorter than those in the control group,the bleeding rate was lower than that in the control group,with statistically significant differences (
P
＜0.05).The total incidence of gastrointestinal spasm,nausea and vomiting,arrhythmia,palpitations and other adverse reactions in the experimental group was 10.00%,lower than that in the control group(33.33%),with statistically significant difference(
P
＜0.05).Procalcitonin(PCT)([0.24±0.04]ng/ml),C-reactive protein(CRP)([8.99±0.54]mg/L),interleukin-2(IL-2)([2.76±0.55]μg/ml)and interleukin-1 levels(IL-1β)([3.00±0.77]μg/ml)in the experimental group were lower than those in the control group for the levels of PCT([0.31±0.06]ng/ml),CRP([14.23±2.01]mg/L),IL-2([3.18±0.60]μg/ml)and IL-1β([3.62±0.96]μg/ml),the differences were statistically significant(
P
＜0.05).
Conclusion
Octreotide combined with Omeprazole can effectively eliminate inflammation,shorten hemostasis time,reduce rebleeding rate,shorten hospital stay and promote the recovery of patients with cirrhosis complicated with upper gastrointestinal bleeding under the premise of ensuring the safety of treatment.
2020 Vol. 27 (24): 87-90 [
Abstract
] (
37
)
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9
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91
Effect and safety of large dose Ambroxol in the treatment of severe pneumonia
DINGShuang
Objective
To investigate the effect and safety of large dose Ambroxol in the treatment of severe pneumonia.
Methods
A total of 100 patients with severe pneumonia admitted to our hospital from August 2016 to July 2019 were selected as the study objects.According to the random number table method,they were divided into the control group and the observation group,with 50 patients in each group.The recovery time of symptoms and signs,the level of inflammatory indicators,the total effectiveness of treatment and the occurrence of adverse reactions were compared between the two groups.
Results
After treatment,the white blood cell count([5.72±0.61]×10
9
/L),C-reactive protein([23.46±2.25]mg/L),procalcitonin ([0.16±0.02]ng/ml),interleukin-6 ([29.37±2.66]pg/ml)in the observation group were lower than those in the control group for white blood cell count([7.96±0.83]×10
9
/L),C-reactive protein([35.81±3.40]mg/L),procalcitonin([0.34±0.03]ng/ml),interleukin-6([38.95±3.76]pg/ml),the differences were statistically significant(
P
＜0.05).The total effective rate in the observation group which was 96.00%,which was higher than that in the control group accounting for 82.00%,the difference was statistically significant(
P
＜0.05).There was no significant difference in the total incidence of adverse reactions between the observation group(8.00%)and the control group(10.00%)(
P
＞0.05).
Conclusion
Large dose Ambroxol has a significant therapeutic effect treating patients with severe pneumonia,which can significantly reduce the level of various inflammatory indicators,shorten the recovery time,and will not increase the incidence of adverse reactions,so it is worth promoting and using in clinical practice.
2020 Vol. 27 (24): 91-93 [
Abstract
] (
40
)
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10
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94
Effect of graded motor imagery therapy combined with routine occupational therapy on the quality of life of hemiplegic patients
YANG Yu-feng REN Ru-fang CHEN Rui-dan LUO Jie-ting YE Li-han
Objective
To explore the effect of graded motor imagery therapy combined with routine occupational therapy on the quality of life of hemiplegic patients.
Methods
A total of 60 stroke patients with hemiplegia admitted to the First People′s Hospital of Zhaoqing City from January 2018 to December 2019 were selected as the research objects,and divided into the study group and the control group according to the random number table,with 30 cases in each group.The control group was treated with routine occupational therapy,and the study group was treated with graded motor imagery therapy on the basis of the control group.Before treatment and 6 weeks after treatment,the two groups of patients′self-care ability of daily life(instrumental activities of daily living[IADL]),activity ability(Canadian occupational performance measure [COPM]),total quality of life (World health organization-quality of life short version[WHO-QOL-BREF]),basic quality of life(quality of life summary[SF-36])score changes were compared.
Results
After 6 weeks of treatment,the scores of IADL,COPM,WHO-QOL-BREF and SF-36 in the study group were higher than those before treatment,and the differences were statistically significant(
P
＜0.05);and the scores of IADL,COPM,WHO-QOL-BREF and SF-36 in the study group were higher than those in the control group,the differences were statistically significant(
P
＜0.05).
Conclusion
The application of graded motor imagination therapy combined with routine occupational therapy in hemiplegic patients with stroke is beneficial to improve patients′daily life self-care ability and activity ability,and improve the quality of life.
2020 Vol. 27 (24): 94-98 [
Abstract
] (
36
)
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8
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99
Edaravone;ICU;Acute ischemic hypoxic encephalopathy;Treatment effect;Adverse reactions
CHEN Man-ni
Objective
To study the effect of Edaravone on ICU acute ischemic hypoxic encephalopathy.
Methods
A total of 52 patients with acute ischemic hypoxic encephalopathy from January 2017 to January 2019 in our hospital′s ICU for treatment were selected as the research objects,and were divided into control group (
n
=26)and observation group(
n
=26)according to the random drawing method.The control group was treated mechanical assisted ventilation to improve the cerebral circulation and maintain the vital signs of the patients.The observation group was treated with Edaravone based on the treatment in the control group.After two courses of treatment,the treatment effect,neurological deficit scores before and after treatment and the occurrence of adverse reactions were compared between the two groups.
Results
The total effective rate of treatment in the observation group (92.3%)was higher than that in the control group (73.1%),the difference was statistically significant(
P
＜0.05);before treatment and on the 7
th
day after treatment,the neurological deficits scores of patients in the two groups,the differences were not statistically significant(
P
＞0.05).On the 14
th
and 28
th
days after treatment,the neurological deficit scores of the two groups of patients were lower than those of the group before treatment,and the neurological deficit scores of the observation group were lower than those of the control group on the 14
th
and 28
th
days after treatment,the differences were statistically significant(
P
＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(
P
＜0.05).
Conclusion
The use of Edaravone in the treatment of acute ischemic hypoxic encephalopathy in ICU has a good effect,can improve patients′neurological deficits and reduce the occurrence of adverse reactions,and has high clinical application value.
2020 Vol. 27 (24): 99-101 [
Abstract
] (
31
)
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11
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102
Expression and distribution of GAD-65/67 in 23 patients with epileptogenic forcal cortical dysplasia
RAO Ying-hua1 ZHANG Xun1 QIN Ming-jun1 HU Bin2
Objective
To explore the expression and distribution of GAD-65/67 in patients with forcal cortical dysplasia(FCD)epilepsy.
Methods
Surgical focus specimen of inpatients were collected from the Affiliated Brain Hospital of Guangzhou Medical University and the Affiliated Second Hospital of Guangzhou Medical University from October 2017 to October 2019.The expression of GAD-65/67 was observed by immunohistochemical staining in 23 patients with FCD epilepsy who underwent surgical resection (the experimental group)and 7 normal brain tissues without epilepsy(the control group).All the stained sections were examined under a microscope and photographed with a digital camera and the image chromatic aberration was analyzed by IEE 7.0 software.
Results
The expression of GAD-65/67 was found in both the experimental group and the control group.In the control group,GAD-65/67 was found to be evenly distributed in nerve fibers and synapses in brain tissue.In the experimental group,abnormal morphology and arrangement of neurons were observed and the expression and distribution of GAD-65/67 were changed correspondingly.
Conclusion
This study suggests that the abnormal distribution of GAD-65/67 may be attributed to the abnormal development of cerebral cortex in FCD,resulting in the decrease of GABA inhibition.
2020 Vol. 27 (24): 102-105 [
Abstract
] (
30
)
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13
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106
Process laparoscopic left lateral hepatic lobectomy;Open left lateral hepatic lobectomy;Liver function;Complications;Primary hospitals
DENG Gao-wang DING Jin-huo
Objective
To study the feasibility of process laparoscopic left lateral hepatic lobectomy in primary hospitals.
Methods
The clinical data of 82 patients with liver diseases treated in our hospital from January 2016 to August 2019 were retrospectively analyzed,and they were divided into three groups according to the different treatment methods.The 26 patients who received the treatment of open left lateral hepatic lobectomy were divided into the open group,the 28 patients who received the treatment of conventional laparoscopic left lateral hepatic lobectomy were divided into conventional laparoscopic group,and the 28 patients who received the treatment of process laparoscopic left lateral hepatic lobectomy were divided into process laparoscopic group.The perioperative indexes,liver function indexes(alanine transaminase[ALT],aspartate aminotransferase[AST])and complications of the three groups were compared.
Results
The intraoperative blood loss of the patients in the process laparoscopy group was less than that of the conventional laparoscopy group and the open group,the operation time and gastrointestinal recovery time were shorter than those of the conventional laparoscopy group and the open group,the differences were statistically significant(
P
＜0.05);The hospitalization time of patients in the process laparoscopic group and the conventional laparoscopic group was shorter than that of the open group,and the difference was statistically significant(
P
＜0.05).The ALT and AST of the postoperative process laparoscopy group and the conventional laparoscopy group were lower than those of the open group,the differences were statistically significant(
P
＜0.05).There were no significant differences in the total incidence of complications among the three groups of patients(
P
＞0.05).
Conclusion
The patients process laparoscopic left lateral hepatic lobectomyhave less intraoperative bleeding,less trauma and quick recovery after surgery,and postoperative complications have not increased.The feasibility and safety of development in primary hospitals are relatively high.
2020 Vol. 27 (24): 106-109 [
Abstract
] (
30
)
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9
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110
Application of lipolytic solution in modified radical mastectomy of breast cancer under endoscopy
XU Wang YU Kun-lin JIN Zhong-kui LIU Chang-shan LUO Cai-lu
Objective
To explore the application effect of lipolytic solution in modified radical mastectomy of breast cancer under endoscopy.
Methods
A total of 90 patients who underwent laparoscopic modified radical mastectomy for breast cancer treated in our hospital from June 2018 to September 2019 were selected as the research objects for retrospective analysis.The patients were divided into group A and group B according to whether they used lipolytic solution adjuvant therapy,45 cases in each group.Patients in group A were treated with lipolysis for axillary lymph node dissection for breast cancer,and patients in group B were treated with axillary lymph node dissection with preserving intercostal brachial nerves.The operation-related indicators,drainage fluid and postoperative complications were compared between the two groups.
Results
The cleaning time,total operation time,and drainage time in the group A were shorter than those in the group B,the differences were statistically significant(
P
＜0.05);the intraoperative blood loss in the group A was less than that in the group B,and the difference was statistically significant(
P
＜0.05);the number of lymph node dissections in group A was more than that in group B,the difference was statistically significant(
P
＜0.05).The drainage fluid of the two groups of patients at 2,3,and 4 days after surgery was less than that in the group at 1 day after surgery,and the drainage fluid of group A was less than that in the group B at 1,2,3,and 4 days after surgery,the differences were statistically significant(
P
＜0.05).The total incidence of postoperative complications in group A was lower than that in the group B,and the difference was statistically significant(
P
＜0.05).
Conclusion
The lipolytic solution has a good effect in the modified radical mastectomy of breast cancer under laparoscopic surgery,which can significantly improve the operation-related indicators of patients and reduce the incidence of complications.
2020 Vol. 27 (24): 110-113 [
Abstract
] (
36
)
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(0 KB) (
13
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114
Effect of Paishi Lidan Decoction combined with laparoscopic minimally invasive treatment of extrahepatic bile duct stones
ZHANGWen-tao
Objective
To explore the clinical effect of Paishi Lidan Decoction combined with laparoscopic minimally invasive treatment of extrahepatic bile duct stones.
Methods
A total of 158 patients with extrahepatic bile duct stones admitted to our hospital from August 2015 to July 2017 were selected as the research objects,and they were divided into observation group (79 cases)and control group (79 cases)by random number table method,and both the two groups were treated with laparoscopic minimally invasive treatment,the control group was treated with antibiotics and Magnesium Sulfate after surgery,the observation group was treated with Paishi Lidan Decoction after surgery,and the clinical efficacy were compared between the two groups.
Results
The total effective rate of clinical treatment in the observation group higher than that in the control group,the difference was statistically significant(
P
＜0.05);the anal exhaust time,gastrointestinal function recovery time and hospitalization time in the observation group were shorter than those in the control group,the differences were statistically significant(
P
＜0.05).After treatment,the total bile acid(TBA),total bilirubin(TBil),conjugated bilirubin(CB)and unconjugated bilirubin(UCB)in the observation group were lower than those in the control group,the differences were statistically significant(
P
＜0.05);the total incidence rate of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant(
P
＜0.05).
Conclusion
Paishi Lidan Decoction combined with laparoscopic minimally invasive treatment of extrahepatic bile duct stones has a significant clinical effect,which can promote rapid recovery of patients,improve liver function and have fewer adverse reactions.
2020 Vol. 27 (24): 114-117 [
Abstract
] (
26
)
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12
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118
Clinical effect of minimally invasive hemorrhoid surgery in patients with severe hemorrhoids
ZHANGZhen-bo
objective
To explore the clinical effect of minimally invasive hemorrhoid surgery in patients with severe hemorrhoids.
Methods
A total of 106 patients with severe hemorrhoids admitted to our hospital from August 2018 to August 2019 were selected as the research objects,and they were divided into reference group (53 cases)and study group(53 cases)by random number table method.The reference group were treated with traditional hemorrhoid surgery method,the study group were treated with minimally invasive hemorrhoid surgery method.The two groups of patients were compared in terms of intraoperative blood loss,hospitalization time,wound healing time,operation duration,total effective rate of treatment,and total incidence of adverse reactions.
Results
The intraoperative blood loss in the study group was less than that in the reference group,the difference was statistically significant(
P
＜0.05);the hospitalization time,wound healing time and operation duration in the study group were shorter than those in the reference group,and the differences were statistically significant (
P
＜0.05).The total effective rate of treatment in the study group was 94.34%,which was higher than that in the reference group of 64.15%,the difference was statistically significant(
P
＜0.05);the total incidence rate of adverse reactions in the study group was 9.43%,which was lower than that in the reference group of 33.96%,the difference was statistically significant(
P
＜0.05).
Conclusion
Minimally invasive hemorrhoid surgery has an ideal effect in the treatment of severe hemorrhoids.Because of the small damage,the wound healing time is significantly shortened,the recovery is faster,the adverse reactions rates are significantly reduced,and the clinical application value is high.
2020 Vol. 27 (24): 118-120 [
Abstract
] (
28
)
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10
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121
Influence of resistance training on cancer-related fatigue and quality of life in elderly cancer patients undergoing chemotherapy
PENGJin-di ZHANGTao WU Xia-xia
Objective
To explore the influence of resistance training on cancer-related fatigue(CRF)and quality of life in elderly cancer patients undergoing chemotherapy.
Methods
A total of 60 elderly cancer patients undergoing chemotherapy who were treated in our hospital from September 2018 to September 2019 were selected as the observation objects,and they were divided into the intervention group and the control group according to the random number table,30 cases in each group.The control group received daily training,and the intervention group received resistance training.The improvement of brief fatigue inventory(BFI)and quality of life questionnaire：C30(QLQ-C30)after intervention were compared between the two groups.
Results
After intervention,the QLQ-C30 score (physical condition,role function,emotional state,cognitive status,social function and overall health/quality of life)of the intervention group were higher than those of the control group (
P
＜0.05).The total incidence of CRF in the intervention group was 73.33%,which was lower than that in the control group(96.67%)(
P
＜0.05).
Conclusion
The elderly cancer patients undergoing chemotherapy with resistance training can significantly improve their CRF,promote the quality of life.
2020 Vol. 27 (24): 121-123 [
Abstract
] (
28
)
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10
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124
Advanced colorectal cancer;Capecitabine;Oxaliplatin;Serum tumor markers;Immune function
ZOU Yu-bin YANGLing XIAOChi-jin CHEN Kai
Objective
To observe the influence of Capecitabine and Oxaliplatin on serum tumor marker levels in patients with advanced colorectal cancer.
Methods
A total of 85 patients with advanced colorectal cancer treated in our hospital from June2017 to May 2019 wereselected and divided intotheobservation group(43 cases)and thecontrol group(42 cases)according to the random number table method.The control group received Fluorouracil and Oxaliplatin treatment,and the observation group received Oxaliplatin and Capecitabine treatment.The clinical efficacy,serum tumor marker levels,immune function and adverse reactions were compared between the two groups.
Results
The clinical response rate in the observation group was 67.44%,which was higher than that in the control group(42.86%),the difference was statistically significant(
P
＜0.05).The level of CA125([43.09±5.63]μg/ml)and CA199([67.39±7.42]μg/ml)in the observation group after chemotherapy were lower than those in the control group ([58.61±4.81]μg/ml,[83.75±9.58]μg/ml),the level of CD4
+
([36.79±4.53]%),CD4
+
/CD8
+
([1.32±0.43])in the observation group after chemotherapy were higher than those in the control group([31.24±4.85]%,[1.11±0.39]),the differences were statistically significant(
P
＜0.05).There was no significant difference in the level of CD8
+
between the two groups before and after chemotherapy(
P
＞0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(
P
＞0.05).Conclusion The combination of Capecitabine and Oxaliplatin in the treatment of advanced colorectal cancer can improve the short-term efficacy,improve the immune function of patients,adjust the level of serum tumor markers,and have fewer adverse reactions.It is an effective and relatively safe chemotherapy in the treatment of advanced colorectal cancer.
2020 Vol. 27 (24): 124-126转130 [
Abstract
] (
22
)
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127
Analysis of BRCA1/2 gene mutation status and clinic characteristics in patients with triple-negative breast cancer
WANGYi-nuo JIN Feng▲
Objective
To analyze the mutation status and clinic characteristics of breast cancer susceptibility gene(BRCA)1/2 in patients with triple-negative breast cancer(TNBC).
Methods
From April 2017 to April 2019,55 patients with TNBC treated in our hospital were selected as the research objects.Reverse transcription polymerase chain reaction (PCR)method and DNA sequence sequencing method were used to determine the mutation of BRCA1/2 gene on the pathological tissue sections of all patients.Analyze the characteristics of BRCA1/2 gene mutation in TNBCpatients,and divide them into mutation group and non-mutation group according to whether there are gene mutations,and the clinical data of the two groups of patients were compared and analyzed.
Results
A total of 9 cases of BRCA1/2 gene mutation were detected in 55 patients with TNBC,including 6 cases of BRCA1 gene mutation and 3 cases of BRCA2 gene mutation,the total detection rate was 16.36%.There were no significant differences in the age,menstrual status,tumor size,pathological type,lymph node metastasis,and clinical stage between the mutation group and the non-mutation group (
P
＞0.05).The proportion of breast cancer family history in the mutation group was higher than that in the non-mutation group,and the difference was statistically significant(
P
＜0.05).
Conclusion
The incidence of BRCA1/2 gene mutation is higher in TNBC patients,and the proportion of breast cancer family history in patients with BRCA1/2 gene mutation is higher.
2020 Vol. 27 (24): 127-130 [
Abstract
] (
23
)
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131
Effect of early rehabilitation on children with cerebral palsy in welfare institutions
LI Jin-ling HUANG Hong-liang CUI Wen-rui
Objective
To explore the clinical effect of early rehabilitation treatment on children with cerebral palsy(CP)in welfare institutions.
Methods
A total of 60 children with CPaged 1 to 6 years who were admitted to our hospital from June 2018 to June 2019 were selected.They were divided into three groups according to age：group A (1 to 2 years old)18 cases,group B(＞2 to 4 years old)20 cases,and group C(＞4 to 6 years old)20 cases.All of them were treated with rehabilitation treatment.After treatment,the therapeutic effect of three groups was compared.
Results
The total effective rate (100.00%)of the group A was higher than that of the group B (83.33%)and the group C (80.00%),with statistical difference(
P
＜0.05).After treatment,the developmental quotient of adaptive behavior,large motor,fine motor,language and individual-social behavior in the group A was better than that in the group B and the group C,with statistical differences (
P
＜0.05).
Conclusion
Early use of rehabilitation programs for children with CP in welfare institutions have an important application value.The earlier rehabilitation programs are carried out,the better the effect will be.Therefore,it is worthy of promotion and application.
2020 Vol. 27 (24): 131-133转137 [
Abstract
] (
23
)
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134
Application of open food provocation test in infants with digestive tract milk protein allergy
LE Qing-sheng FAN Xiao-yan ZHANG Xiao-wen SHAO-jun
Objective
To explore the application of open food provocation test(OFC)in infants with digestive tract milk protein allergy.
Methods
From January 2018 to March 2020,50 children with suspected digestive tract milk protein allergies were selected as the research objects.After hospitalization,milk protein was used to implement OFC.The clinical characteristics and OFC test results of 50 children were analyzed.
Results
OFCresults of 50 cases showed that 4 cases were negative(8.00%)and 46 cases were positive(92.00%).Among them,there were 41 cases(89.13%)with delayed anaphylaxis and 5 cases(10.87%)with tachycardia.Among the 50 cases,27 cases were blood stool(54.00%),25 cases were diarrhea(50.00%),5 cases were vomiting(10.00%),3 cases were rash(6.00%),and 2 cases were milk rejection (4.00%).There were no significant differences in monthly age,sex and clinical manifestations between the negative group and the positive group (
P
＞0.05).There were no significant differences in neutrophil,white blood cell and platelet levels between the negative group and the positive group before and after the stimulation test(
P
＞0.05).The level of neutrophils in the positive group after stimulation test was(3.48±1.64)×10
9
/L,which was higher than that before stimulation test of(2.52±1.07)×10
9
/L,with statistically significant difference(
P
＜0.05).
Conclusion
A negative OFC test can rule out digestive food allergies caused by provocative foods,guide clinical interventions as soon as possible,avoid unnecessary dietary avoidance,and help children recover as soon as possible.
2020 Vol. 27 (24): 134-137 [
Abstract
] (
25
)
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8
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138
Effect of laparoscopic salpingography on the function of ovarian reserve
MAOYa-xian
Objective
To investigate the effect of laparoscopic fallopian tube surgery on ovarian reserve function.
Methods
A total of 60 cases of tubal pregnancy who underwent laparoscopic salpingotomy in our hospital from June 2016 to May 2019 were selected and analyzed retrospectively,and the patients were divided into control group (
n
=30)and study group (
n
=30)according to different operation methods.In the control group,the laparoscopic salpingectomy was used,and the study group adopted the laparoscopic salpingectomy.The ovarian reserve index before and after operation,immune response index before and after operation,inflammatory response index before and after operation,and
in vitro
fertilization-embryo transfer(IVF-ET)outcomes were compared between the two groups.
Results
There was no significant difference in ovarian reserve index between the two groups before operation (
P
＞0.05).The number of antral follicles,anti-Muller tube hormone (AMT)and egg in the study group were higher than those in the control group,with statistical differences (
P
＜0.05).There was no significant difference between the two groups of pre-operative immune response(
P
＞0.05).The number of CD3
+
and CD4
+
in the study group was higher than that of the control group(
P
＜0.05).The postoperative CD8
+
in the study group was lower than that in the control group,with statistical difference(
P
＜0.05).There was no significant difference in inflammatory response between the two groups before operation(
P
＞0.05).The tumor necrosis factor-α(TNF-α),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6)of the study group were higher than those of the control group,and the differences were statistically significant(
P
＜0.05).The results of the two groups of IVF-ET included the embryo implantation rate,the clinical pregnancy rate,the early abortion rate and the differences showed no statistical significance(
P
＞0.05).
Conclusion
Laparoscopic fallopian tube fenestration can effectively reduce the adverse effects of ovarian reserve,immune inflammatory reaction and inflammatory reaction index.It is effective in the treatment of ovarian reserve,and has important clinical application value.
2020 Vol. 27 (24): 138-140转144 [
Abstract
] (
24
)
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16
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141
Application of single-hole laparoscopy in patients with tubal pregnancy
OUYANG Qiu1 SONG Shu-hong1 XI Zhi-zhen1 LI Ji-mei2 ZHOU Zhao-lian1
Objective
To explore the application effect of single-hole laparoscopy in patients with tubal pregnancy.
Methods
A total of 60 patients with tubal pregnancy who were treated in People′s Hospital of Jishui County from April to November 2019 were selected as subjects and divided into two groups according to the random number table method,30 cases in each group.The control group underwent three-hole laparoscopy,and the study group underwent single-hole laparoscopy.The operation time,intraoperative blood loss,exhaust time,length of hospital stay,incision pain,satisfaction and treatment efficacy were compared between the two groups of patients.
Results
The operation time in the study group was longer than that in the control group,and the hospital stay was shorter than that in the control group,the differences were statistically significant(
P
＜0.05).Comparison of preoperative visual analogue scale(VAS)scores between the two groups showed no statistically significant difference (
P
＞0.05).At 1 and 3 days after the operation,the VASscores of the two groups were lower than those of the two groups,and the VASscores of study group were lower than that in the control group,and the differences were statistically significant(
P
＜0.05).The total satisfaction of the study group was 93.33%,higher than that in the control group of 70.00%,the difference was statistically significant(P＜0.05);the total effective rate of treatment in the study group was 96.66%,which was higher than that in the control group of 80.00%,the difference was statistically significant(
P
＜0.05).There were no significant differences in intraoperative blood loss and exhaust time between the two groups (
P
＞0.05).
Conclusion
In the clinical treatment of tubal pregnancy patients,single-hole laparoscopic surgery can effectively reduce the patients′pain,improve the satisfaction of clinical treatment,further shorten the length of hospitalization of the patient,and allow the patients to recover as soon as possible.It has high clinical application value.
2020 Vol. 27 (24): 141-144 [
Abstract
] (
27
)
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145
Study on the nursing effect of heat sensitive moxibustion combined with acupoint massage in the rapid rehabilitation of patients after laparoscopic hysterectomy
YU Li-min JIA Li-xia LUO Jiang-hua
Objective
To study the nursing effect of heat sensitive moxibustion combined with acupoint massage in the rapid rehabilitation of patients after laparoscopic hysterectomy.
Methods
From December 2018 to December 2019,60 cases of laparoscopic hysterectomy patients who were treated in our hospital were selected as the research objects.They were divided into group A(
n
=30,heat sensitive moxibustion)and group B(
n
=30,heat sensitive moxibustion+acupoint massage)by using the method of random comprehensive balance.The hand operation indexes,clinical efficacy,total complication rate and total satisfaction degree of the two groups were compared.
Results
The first defecation time,the first anal exhaust time and the bowel sounds recovery time in group B were shorter than those in group A;the total effective rate of group B was higher than that of group A;the total incidence of complications such as urinary retention,intestinal obstruction,deep vein thrombosis in group B was lower than that in group A,the total nursing satisfaction of group B was higher than that of group A,the differences were statistically significant(
P
＜0.05).
Conclusion
The application of heat sensitive moxibustion combined with acupoint massage in the rapid rehabilitation of patients after laparoscopic hysterectomy can shorten the first defecation time,the first anal exhaust time,the recovery time of bowel sounds,enhance the clinical effect and reduce complications,improve nursing satisfaction,which is worthy of clinical application.
2020 Vol. 27 (24): 145-147 [
Abstract
] (
28
)
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148
Nursing research on chewing gum to promote gastrointestinal function recovery after cesarean section
LI Shuang-shuang ZHONGMei-ling AOYu-min HU Li-hua
Objective
To explore the nursing effect of chewing gum on gastrointestinal function recovery after cesarean section.
Methods
A total of 101 cases of cesarean section women in our hospital from December 2018 to December 2019 were selected as the study objects,and were divided into control group (
n
=50)and observation group (
n
=51)according to the random number table method.The control group was given routine nursing and the observation group chewed gum on that basis.The time index,complications and total nursing satisfaction of the two groups were compared.
Results
The time of first exhaust,first hearing and bowel sounds in the observation group were earlier than those in the control group,and the hospitalization time was shorter than that in the control group,the differences were statistically significant(
P
＜0.05).There was no significant difference between the two groups in the time of first defecation(
P
＞0.05).The total incidence of complications in the observation group was lower than that in the control group (
P
＜0.05).The nursing total satisfaction of the observation group was higher than that of the control group,the difference was statistically significant(
P
＜0.05).
Conclusion
Chewing gum after cesarean section can promote the recovery of gastrointestinal function,shorten the first exhaust time,reduce the incidence of postoperative enteroparalysis,and shorten the hospital stay,but it has no significant effect on the first defecation time.
2020 Vol. 27 (24): 148-150 [
Abstract
] (
30
)
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(35 KB)
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11
)
151
Clinical effect of probiotics combined with Lactase in the treatment of chronic diarrhea caused by lactose intolerance in infants and young children
ZHANG Ying HUANG Ming-Jian ZHANG Kai-Zhen
Objective
To explore the clinical effect of probiotics combined with Lactase in the treatment of chronic diarrhea caused by lactose intolerance in infants and young children.
Methods
A total of 36 children with chronic diarrhea caused by lactose intolerance admitted to our hospital from August 2019 to January 2020 were selected as the research objects,and they were divided into the control group and the observation group according to the random number table method,with 18 cases in each group.The control group was treated with Lactase,and the observation group was treated with probiotics(Clostridium Caseate Bivalent Viable Powder)combined Lactase.Treatment effect,number of diarrhea,number of vomiting and weight changes were compared between two groups of children.
Results
The total effective rate of treatment of children in the observation group was 94.44%,which was higher than that of the control group of 83.33%,the difference was statistically significant(
P
＜0.05).After treatment,the numbers of diarrhea and milking in the observation group were fewer than those in the control group,and the weight was higher than that in the control group,the differences were statistically significant(
P
＜0.05).
Conclusion
The combination of probiotics and Lactase is effective in treating chronic diarrhea caused by lactose intolerance in infants and young children.It can effectively reducing the frequency of diarrhea and vomiting in children,increasing the weight of children,and is worthy of clinical application.
2020 Vol. 27 (24): 151-153 [
Abstract
] (
24
)
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10
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154
Application effect of prenatal care intervention in patients with pernicious placenta previa
WANG Zi-jing
Objective
To investigate the effect of prenatal care on patients with pernicious placenta previa.Methods One hundred patients with pernicious placenta previa from March 2017 to March 2018 in our hospital were enrolled in the study.According to the random number table method,they were equally divided into the control group and the study group,50 cases in each group.In the control group,the general nursing was used,while in the study group,the prenatal care as an intervention was adopted.The delivery indicators of the two groups were compared and analyzed,including postpartum hemorrhage,time of termination of pregnancy,neonatal weight,neonatal Apgar score,and postpartum hospital stay.The mental state scores of the two groups were compared before and after nursing,including the scores of self-rating anxiety scale(SAS)score,self-rating depression scale(SDS).The incidence of complications was compared between the two groups.The total satisfaction of clinical nursing was compared between the two groups.
Results
The amount of postpartum hemorrhage of the study group was (776.20±574.00)ml,lower than that of the control group of(1282.30±1145.85)ml,the difference was statistically significant(
P
＜0.05).The termination of pregnancy time of the study group was(35.90±1.95)weeks,shorter than that of the control group of(39.60±3.05)weeks,the difference was statistically significant(
P
＜0.05).The neonatal weight of the study group was(2.85±0.45)kg,higher than that of the control group of(2.10±0.70)kg,the difference was statistically significant(
P
＜0.05).The neonatal Apgar score was(9.30±0.70)points in the study group,higher than that in the control group of(8.75±1.40)points,the difference was statistically significant(
P
＜0.05).The postpartum hospital stay was(4.70±1.65)d in the study group,shorter than that in the control group of(6.05±3.50)d,the difference was statistically significant(
P
＜0.05).There were no significant differences in the SASand SDSscores before nursing (
P
＞0.05).The SASand SDSscores after nursing were (41.85±1.35)points and(40.75±1.20)points in the study group,lower than those in the control group of(49.35±1.70)and(49.95±1.85)points,with statistically significant differences(
P
＜0.05).The total incidence of complications of the study group was 4.00%,lower than that in the control group accounting for 22.00%,with statistically significant differences (
P
＜0.05).The total clinical nursing satisfaction of the study group was 98.00%,higher than that of the control group accounting for 86.00%,with statistically significant differences(
P
＜0.05).
Conclusion
The effect of prenatal care as an intervention in pernicious placenta previa patients is definitive.
2020 Vol. 27 (24): 154-157 [
Abstract
] (
23
)
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8
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158
Application of marrow morphology combined immunotyping in chronic lymphoblastic leukemia
ZHOU Yue-ping
Objective
To explore the application of bone marrow morphology combined with immunotyping in chronic lymphocytic leukemia.
Methods
From May 2015 to December 2018,80 patients with chronic lymphocytic leukemia admitted to our hospital were tested for immunophenotypes in bone marrow or peripheral blood samples by flow cytometry.Immunophenotype detection was performed on bone marrow or peripheral blood samples by flow cytometry.According to the cell morphology,they were divided into typical group (65 cases)and mixed group(15 cases).The morphological characteristics and immunotyping of bone marrow were analyzed,and the positive rates of antigen expression in the two groups were compared.
Results
In terms of the morphological characteristics of bone marrow,the proportion of lymphocytes increased significantly in all patients,accompanied by different proportions of juvenile lymphocytes,granulocytes,red lines and megakaryons showed different degrees of decrease.Among the 80 patients,the positive rates of antigen expression were CD
19
,HLA-DR,CD
5
,CD
20
,CD
22
,CD
23
,CD
38
and FMC-7 in descending order.There were no statistically significant differences in the positive expression rates of CD
5
,CD
19
,CD
20
,CD
22
,CD
23
,FMC-7and HLA-DR between the two groups(
P
＞0.05),but the positive expression rate of CD
38
in the mixed group was higher than that in the typical group,the difference was statistically significant(
P
＜0.05).
Conclusion
In the clinical examination of chronic lymphocytic leukemia,bone marrow morphology combined with immunotyping has certain diagnostic and differential effects,but it still needs to be further confirmed.
2020 Vol. 27 (24): 158-160 [
Abstract
] (
27
)
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7
)
161
Differential diagnosis of troponin T,N-terminal brain natriuretic peptide and D-dimer in patients with acute myocardial infarction and early chest pain
SHE Ji-jia LU Tian-tian WU Chang-lin LI Zhuo-cheng ZHONG Xiao-mei
Objective
To differentially diagnose patients with acute myocardial infarction(AMI)and early chest pain by jointly detecting the contents of whole blood troponin T(cTnT),N-terminal brain natriuretic peptide(NT-proBNP)and D-dimer（D-D）assessment of the patient′s prognosis.
Methods
A total of 157 patients with chest pain admitted to the emergency department in our hospital from March 2018 to October 2019 were selected as the research objects.According to the screening criteria,the patients were divided into cardiogenic chest pain group(
n
=88)and non-cardiogenic chest pain group(
n
=69),and the healthy group was used as the control group(
n
=46),all the subjects were tested for cTnT,NT-proBNPand D-D,and at the same time the change trend of cTnT,NT-proBNPand D-D after the patient admitted to hospital was folloued up and then the prognosis of the patients was evaluated.
Results
The levels of cTnT,NT-proBNPand D-D in the two patient groups were higher than those in the healthy group,the differences were statistically significant(
P
＜0.05).The levels of cTnT and NT-proBNPin the cardiogenic chest pain group were higher than those in the non-cardiogenic chest pain group,the differences were statistically significant(
P
＜0.05).The level of D-D in the non-cardiac chest pain group was significantly higher than that in the cardiogenic chest pain group,the difference was statistically significant(
P
＜0.05).The receiver operator characteristic (ROC)curve analysis of its prognosis showed that the change trend of cTnT,NT-proBNP and D-D levels in whole blood could be used to evaluate the prognosis of patients with chest pain,and the sensitivity and specificity of each index were high.
Conclusion
The combined detection of cTnT,NT-proBNPand D-D can be used as an important indicator for the differential diagnosis of chest pain in patients with cardiogenic or non-cardiogenic chest pain,and it has important value for the prognosis of patients.
2020 Vol. 27 (24): 161-164 [
Abstract
] (
26
)
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(39 KB)
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(0 KB) (
9
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165
Investigation and study on the incidence and cognition of postpartum urinary incontinence and constipation in our hospital
WAN Man-hong LIAN Ren-hua ZHI Mei-fang TANG Guang-xian
Objective To investigate the prevalence of postpartum urinary incontinence and constipation,and analyze the maternal cognition of postpartum urinary incontinence and constipation.Methods Using the convenience sampling method,500 parturients admitted to our hospital from January to March 2019 were selected as the research objects.The prevalence rate of postpartum urinary incontinence and constipation was counted,and the recognition of urinary incontinence and constipation among parturients was investigated.Results In the 500 parturients,97 cases(19.40%)had only postpartum urinary incontinence,46 cases (9.20%)had only postpartum constipation,and 29 cases (5.80%)had postpartum urinary incontinence with constipation,the total prevalence rate was 34.40% (172/500).There were no significant differences in age,labor times between the patients with urinary incontinence and constipation and those without urinary incontinence and constipation (P＞0.05).There was significant difference in delivery mode between the patients with urinary incontinence and constipation and those without urinary incontinence and constipation(P＜0.05).The investigation results showed that the cognitive status of urinary incontinence and constipation in 500 parturients was lower.There was no significant difference in the cognitive status of parturients with urinary incontinence and constipation and those without urinary incontinence and constipation(P＞0.05).Conclusion The incidence of postpartum urinary incontinence and constipation is higher,the mode of delivery may affect the occurrence of postpartum urinary incontinence and constipation,and puerperas′awareness of urinary incontinence and constipation is poor,so health education should be strengthened.
2020 Vol. 27 (24): 165-167 [
Abstract
] (
23
)
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12
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168
Analysis of influencing factors of psychiatric nurses′attitude towards patient violence and violence management strategies
WANG Li1 GUOHua2 HUANG Hui-li3 CHENG Wen-hai4 WANG Tao5
Objective
To understand psychiatric nurses′attitudes towards patients′violence and violence management strategies,and analyze its influencing factors.
Methods
A current survey was conducted of 1165 psychiatric nurses in 31 psychiatric hospitals above grade 2 in Guangdong province from September to December 2019.The personal basic situation table was used to investigate its general situation,Chinese-the management of aggression and violence attitude scale(C-MAVAS)was used to investigate nurses′attitudes towards patients′violence and violence management strategies,the questionnaire method was used to investigate the difficulties encountered by nurses in dealing with patient violence and the factors that influenced the decision-making in handling violence.
Results
The results of univariate analysis showed that there was a statistically significant difference in the C-MAVASscores of nurses of different education levels and positions towards patient violence (
P
＜0.05);The differences in the C-MAVASscores and total scores of the violence management strategies of nurses of different ages,education levels,positions and technical titles were statistically significant(
P
＜0.05).The results of multiple stepwise regression analysis show that education level and position were the influencing factors of nurses′attitude to violence against patients C-MAVASscore,violence management strategy C-MAVASscore and total score(
P
＜0.05),and there was a negative correlation between them.The difficulties that nurses encounter when dealing with patient violence and the factors that affect their decision-making in dealing with violence were mainly the hospital management system,nurses′own skills,patient′s condition,family support,and ward environment.
Conclusion
The attitude of psychiatric nurses to the violence of patients and the strategies of violence management are related to the nurses′age,education level,position and technical title.Hospitals should pay attention to the occupational safety of nurses,do a good job of anti-violence skills training,improve the ability of nurses to deal with violence,and reduce the harm of violence to nurses.
2020 Vol. 27 (24): 168-172转176 [
Abstract
] (
28
)
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(45 KB)
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11
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173
Distribution characteristics and treatment rationality analysis of carbapenem-resistant Gram-negative bacilli in our hospital from January to June 2019
WEIYun FENG Gui-mei WANG Shu-guang YU Yong-wen▲
Objective
To explore the distribution characteristics and treatment rationality of carbapenem-resistant Gram-negative bacilli(CRO)in our hospital from January to June 2019,and provide evidence for clinical rational use of antibiotics.
Methods
The data of CROinfection in our hospital from January to June 2019 were retrospectively analyzed,and the results were statistically analyzed.
Results
A total of 60 CRO strains were detected by our hospital from January to June 2019.The detection rate was 1.43%,mainly carbapenem-resistant
Escherichia coli
(CREC)5 strains(8.3%),carbapenem-resistant
Klebsiella pneumoniae
(CRKP)11 strains(18.3%),carbapenem-resistant
Pseudomonas aeruginosa
(CRPA)14 strains(23.4%),and carbapenem-resistant
Acinetobacter baumannii
(CRAB)30 strains(50.0%).The CRO specimens were mainly from sputum(56 strains),blood(2 strains),and mid-stage urine(2 strains).CRO was resistant to most antibacterial drugs,and was only sensitive to a few Aminoglycosides,Fluoroquinolones,Minocycline,Compound sinomine,Tigecycline (except
Pseudomonas aeruginosa
).
Conclusion
CRO has become an important pathogen in the hospital infection.The supervision of multi-drug resistant bacteria and the rational use of carbapenem antibacterial drugs should be strengthened,and hand hygiene should be paid attention to reduce or avoid the production of multi-drug resistant bacteria.
2020 Vol. 27 (24): 173-176 [
Abstract
] (
25
)
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10
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177
Analysis of the utilization of key monitoring of drugs in a tertiary hospital
WANG Ye1 CHENG Gang2▲
Objective
To observe the situation of the usage about the first batch of the key monitoring drugs by government in some hospital,and to provide the references for strengthening the supervision of the adjuvant drugs,promoting clinical rational drug administration and enhancing the performance assessment.
Methods
The sum of patient payment and the ranking of the key monitoring drugs were collected through the hospital information system (HIS)from January to December 2018 in a hospital.The prescription of the medical records of key monitoring drugs were evaluated and assessed including the indication,usage and dosage,treatment time and inappropriate administration periods,and contraindications.The irrational situations of the drug administration were also summarized.
Results
Eight key monitoring drugs with high ranking of the usage dose in the hospital and a total of 530 medical records related to the eight key monitoring drugs were evaluated,and among of them 149(28.11%)cases were not qualified,which can be classified by four aspects including 33 cases (22.15%)in the phenomena of indication over ranged,51 cases (34.23%)in dosage forms,47 cases(31.54%)in treatment time and inappropriate administration periods,and 18 cases(12.08%)in contraindication.
Conclusion
The key monitoring drugs are used extensively and the irrational phenomena are existed in the hospital.The medical institutions should establish the administration regulation to enforce the supervision of the reasonable drug administration and guarantee the safety,reasonable and economic drug administration.
2020 Vol. 27 (24): 177-180 [
Abstract
] (
31
)
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(42 KB)
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11
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181
Analysis of food safety monitoring situation in a canteen of a military base in Beijing from 2015 to 2019
WANGShan-yu1 YAO Wei1 XIAO Hong1 ZHAO Jing-ping1 CAO Yu-ting1 HUANG Xin1 GENG Xiao-yang1 GAOChun-yu2▲
Objective
To analyze the food safety monitoring situation of a canteen in a military base in Beijing from 2015 to 2019,so as to provide reference and guidance for related work in future.
Methods
Based on 2015-2019 food safety risk monitoring reports of a military base in Beijing,statistical analysis was performed on year,test items,food varieties and other factors.
Results
A total of 7195 samples were tested from a canteen in five years,and 837 were unqualified.The total qualificaton rate was 88.37%.Further analysis found tested samples were most in 2015 and least in 2018.The most tested items were the cleanliness of the tableware and cookware,and the least tested one was mycotoxins.Total bacteria had the highest unqualified rate,followed by illegal or excessive additions,and mycotoxins had the lowest detection rate.According to the analysis of food varieties,legume products had the lowest qualification rate,followed by milk and dairy products,poultry meat and preparations had the third lowest qualification rate.Eggs were ranked in top 1 in qualification rate.
Conclusion
Strengthening food safety monitoring is the most effective measure to ensure food safety and eliminate hidden dangers.
2020 Vol. 27 (24): 181-183转195 [
Abstract
] (
21
)
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(36 KB)
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(0 KB) (
9
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184
Application effect comparison of medical new-type textile and medical cotton cloth in the packaging of disinfection supply center
LI Yun-xia
Objective
To investigate the closure performance and bacteriostasis effect of medical new-type textile and medical ordinary cotton cloth of surgical dressing packs in the sterilization.
Methods
A total of 240 surgical dressing packs of the same specification in our hospital from July to December 2019 were selected,and divide into experimental group and control group by random drawing method,with 120 cases in each group.In the experimental group,the dressing packages for sterilized surgery were packaged by two layers of medical new-type textile(120 cm×120 cm),while in the control group,the dressing packages for sterilized surgery were packaged by two layers of medical cotton cloth(120 cm×120 cm).After sterilization,when all the surgical dressing packages were qualified in chemical indicator card,chemical indicator tape and physical parameter test,the closure performance of the two groups was compared.All sterilized surgical dressings were stored in the sterile storage area,and bacteriological tests were performed at 7,14,30,60,90 and 180 days after storage,and the positive bacterial cultures of the two groups were compared.
Results
After sterilization,there was 1 case of loose package in the closure performance test of the experimental group,no wet package or damage,the closure performance qualification rate was 99.17%.In the control group,there were 5 cases of loose package,5 cases of wet package,11 cases of damage,and the closure performance qualification rate was 82.50%.The closure performance qualification rate of the experimental group was higher than that of the control group,and the difference was statistically significant(
P
＜0.05).Altogether 10 surgical dressings were taken in each of the two groups and stored for 7,14,30,60,90 and 180 days for bacteriological testing,and the results showed that the number of positive bacterial cultures in the experimental group and the control group was both 0 on 7 and 14 days.The number of positive bacterial cultures in the experimental group was 0 at 30,60,90,and 180 days,while that was positive in the control group at 30,60,90,and 180 days.There were statistically significant differences in the positive bacterial cultures between the two groups at 30,60,90,and 180 days(
P
＜0.05).
Conclusion
In terms of closure performance,the closure performance of the sterile dressing package of the medical new-type textile packaging is better than that of the sterile dressing package of the medical ordinary cotton cloth.In terms of bacteriostasis effect,the medical new-type packaging can effectively block bacteria within 180 days,while the medical ordinary cotton cloth packaging can effectively block bacteria within 14 days,but there is no guarantee to effectively block bacteria after 14 days.Therefore,medical new-type textile is worth promoting and using in sterilization supply center packaging.
2020 Vol. 27 (24): 184-187 [
Abstract
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23
)
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188
Analysis of the application effect of continuing health education on improving postpartum pelvic floor function
HUANG Shui-ying1 WANG Rong1 HE Jing2
Objective
To explore the application effect of continuous health education on improving postpartum pelvic floor function.
Methods
A total of 100 cases of full-term normal delivery mothers who were treated in our hospital from January 2019 to January 2020 were selected as research objects.According to the random number table method,they were divided into the observation group(
n
=51)and the control group(
n
=49).The observation group received continuous health education after discharge,and the control group received routine discharge guidance.The training compliance,pelvic floor muscle strength recovery,total incidence of pelvic floor muscle dysfunction and satisfaction were compared between the two groups.
Results
The compliance rate in the observation group was higher than that in the control group,and the difference was statistically significant(
P
＜0.05).The recovery of pelvic floor muscle strength in the observation group was better than that in the control group,and the difference was statistically significant(
P
＜0.05).The total incidence of pelvic floor muscle dysfunction in the observation group was lower than that in the control group,the difference was statistically significant (
P
＜0.05).The total satisfaction rate of the observation group was higher than that in the control group,the difference was statistically significant (
P
＜0.05).
Conclusion
Continuing health education for postpartum women can improve maternal training compliance,improve maternal pelvic floor function,reduce the incidence of pelvic floor muscle dysfunction,and increase maternal satisfaction,which is worthy of promotion and application.
2020 Vol. 27 (24): 188-191 [
Abstract
] (
28
)
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192
Application effect of Critical Thinking and Nursing Clinical Decision-Mak#br# ing course in middle and higher vocational nursing specialty
PAN Tai-jian1，2 MAO Shu-ying2 ZHANG Zhi-hua2 YAN Wen-ying2 ZHANG Yu2▲
Objective
To explore the application effect of
Critical Thinking and Nursing Clinical Decision-Making
course in middle and higher vocational nursing specialty.
Methods
A total of 60 nursing students of grade 2016 from February to July 2019 in Shanghai Pudong New Area Health School were selected as the research objects.They were randomly divided into the experimental group(30 cases)and the control group(30 cases).The experimental group was taught 30 hours
Critical Thinking and Nursing Clinical Decision-Making
course before the transition.The control group did not practice the course.The clinical decision-making ability and satisfaction of the course were compared between the two groups.
Results
The scores of clinical decision-making ability of secondary and higher vocational nursing students were lower,but the scores of total score,weighted total score,goal determination,decision-making,implementation decision-making and evaluation feedback of nursing students in the experimental group were higher than those in the control group,and the difference were statistically significant(
P
≤0.01).There was no significant difference in the the problems found between the two groups(
P
＞0.01).The satisfaction rate of students was 93.1%.
Conclusion
The curriculum setting of
Critical Thinking and Nursing Clinical Decision-Making
course can improve the clinical decisionmaking ability of students majoring in integrative nursing in middle and higher vocational colleges,it is worthy of further teaching practice research and promotion.
2020 Vol. 27 (24): 192-195 [
Abstract
] (
30
)
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196
Experience in strengthening pharmaceutics in the teaching of Dermatovenerology
YANG Bin LI Ai-ping WANG Xing-feng TANG De-mu KONG Wei-ping LIU Hong
Although pharmaceutics is a specialized course in pharmacy,its principles and applications have been involved into all aspects of clinical medicine.Currently,various clinical disciplines generally lack the emphasis on pharmaceutics,and students′theoretical basis of pharmaceutics is also very poor,which is not conducive to clinical learning.Therefore,in the theory and clinical teaching of
Dermatovenerology
,our teaching and research section consciously strengthens the content of pharmaceutics based on the characteristics of this subject.In the theoretical teaching stage,the concept and principle of common dosage forms and preparations are mainly introduced,and the pharmaceutics of traditional Chinese medicine is properly considered to realize the organic combination of“clinical-pathological-pharmaceutical”process.In the clinical teaching stage,treatment room noviciate is added,bedside noviciate should be strengthened,practical application of pharmaceutics theory in this subject should be displayed,and conduct some academic research on the combination of dermatovenerology and pharmaceutics.Through these measures,which helps students to understand the content of
Dermatovenerology
completely and deeply,and deepen the cognition on the treatment and medication of skin and sexually transmitted diseases,which achieved favorable teaching efficiency.
2020 Vol. 27 (24): 196-199 [
Abstract
] (
24
)
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200
Application effect of diversified health education methods in patients with end-stage renal disease undergoing new abdominal transplantable catheter
HUANG Xi-lian YE Li XIAO Ling
Objective
To investigate the application effect of diversified health education methods in patients with end-stage renal disease with new abdominal transplantable catheter.
Methods
A total of 50 patients with end-stage renal disease undergoing new abdominal transplantable catheter admitted to our hospital from December 2013 to December 2018 were selected as the research objects,these patients were divided into the observation group and the control group by random number table method,with 25 cases in each group.The control group was given routine health education method,while the observation group was given diversified health education method.The length of hospital stay and hospitalization expenses of the two groups were compared,and the satisfaction of patients with medical staff in the department of renal medicine was evaluated before intervention and after intervention at 3 months and 6 months.
Results
The length of hospital stay in the observation group after intervention was shorter than that in the control group,and the hospitalization expenses in the observation group after intervention was less than that in the control group (
P
＜0.05).The satisfaction of patients in the two groups after intervention at 6 months was higher than that of after intervention at 3 months(
P
＜0.01).The satisfaction of patients in the observation group at 3 and 6 months after intervention was higher than that in the control group (
P
＜0.01).
Conclusion
Diversified health education can significantly shorten the length of hospital stay,reduce the hospitalization expenses and improve the satisfaction of patients with end-stage renal disease undergoing new abdominal transplantable catheter.
2020 Vol. 27 (24): 200-202 [
Abstract
] (
23
)
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203
Application value of grading nursing in patients with otogenic vertigo
YAN Jian-rong
Objective
To explore the application effect of grading nursing in patients with otogenic vertigo.
Methods
A total of 78 patients with otogenic vertigo admitted to our hospital from August 2018 to December 2019 were selected and divided into control group and observation group according to random number table method,39 cases in each group.The control group was given routine nursing and the observation group was given graded nursing intervention.The incidence of falls,total nursing compliance and total nursing satisfaction were compared between the two groups.
Results
The incidence of falls in the observation group was 2.56%,lower than 20.51%in the control group,the difference was statistically significant(
P
＜0.05);the total compliance rate of nursing in the observation group was 97.44%,and the total satisfaction rate of nursing was 97.44%,respectively higher than 76.92%and 74.36%in the control group,the differences were statistically significant(
P
＜0.05).
Conclusion
Grading nursing can reduce the incidence of falls in patients with otogenic vertigo and improve the compliance and satisfaction of patients.
2020 Vol. 27 (24): 203-205转209 [
Abstract
] (
28
)
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206
Application effect of systematic nursing intervention on constipation in stroke patients with hemiplegia
LI Mei-ping GAO Juan-bi LI Qing-nong▲ FENG Jian-mei
Objective
To analyze the effect of systematic nursing intervention on constipation in stroke (CVA)patients with hemiplegia.
Methods
A total of 300 patients with hemiplegia due to CVA from July 2018 to July 2019 in our hospital were selected as the study subjects.According to the random number table method,they were divided into observation group (
n
=150)and control group (
n
=150).The control group received routine nursing methods.The observation group used routine nursing+systematic nursing methods,the incidence of constipation,defecation,and stroke scale(NIHSS)were compared between two groups.
Results
The incidence of constipation in the observation group was lower than that in the control group,the difference was statistically significant(
P
＜0.05).The defecation time of the observation group was shorter than that of the control group,the frequency of defecation per week was more than that of the control group,the differences were statistically significant(
P
＜0.05).There was no significant difference in constipation symptom score between the two groups before nursing(
P
＞0.05);the symptom scores(abdominal distension,fecal characteristics,spontaneous defecation and defecation effort)were lower than those before nursing,the symptom scores of the observation group were lower than those of the control group,the differences were statistically significant(
P
＜0.05).Comparison of NIHSSscores between the two groups before nursing,the differences had no statistical significance (
P
＞0.05);the NIHSSscores of the two groups after nursing were lower than those before nursing,and the observation group was lower than the control group,the differences were statistically significant(
P
＜0.05).
Conclusion
Systematic nursing intervention for CVA patients with hemiplegia can reduce the incidence of constipation,shorten the time of defecation,increase the number of bowel movements,and at the same time help improve the patient′s condition,which is worth further promotion and application.
2020 Vol. 27 (24): 206-209 [
Abstract
] (
33
)
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210
Effect of postoperative psychological nursing intervention on negative emotion and quality of life of patients undergoing hysterectomy
KOU Wei-jie
Objective
To explore the effect of postoperative psychological nursing intervention on negative emotion and quality of life of patients undergoing hysterectomy.
Methods
A total of 104 patients with hysterectomy treated in our hospital from August 2017 to January 2019 were selected as the research objects.The patients were divided into control group and study group according to different postoperative nursing plan,52 cases in each group.The control group was only given routine nursing intervention,the study group added psychological nursing intervention,the differences in postoperative negative emotions and quality of life between the two groups were compared.
Results
After nursing,the score of the 90-item self-assessment scale (SCL-90)in the study group was lower than that in the control group,and the difference was statistically significant(
P
＜0.05).The WHO quality of life scale(WHOQOL-BRE)scores in the study group and control group at 1 month were higher than those at 1 week after operation,and the WHOQOL-BRE scores at 1 week and 1 month after operation in the study group were higher than those in the control group,the differences were statistically significant(
P
＜0.05).
Conclusion
Psychological nursing intervention can effectively reduce the negative emotion and improve the quality of life of patients during hysterectomy.It is worth learning from clinical.
2020 Vol. 27 (24): 210-212 [
Abstract
] (
29
)
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213
Application of intervention of family centered nursing on children with nephrotic syndrome
WANG Chun-hua
Objective
To discuss the application effect of family centered nursing on children with nephrotic syndrome(NS).
Methods
A total of 92 children with NSin our hospital from May 2017 to October 2018 were selected as the research subjects.All of them were divided into control group and observation group according to the time of treatment,46 cases in each group.Children in control group were given routine pediatric care,and children in observation group carried out family centered nursing intervention.The therapeutic effect,recurrence rates within 6 months were compared,and the quality of life was evaluated by the subjective quality of life questionnaire for children (ISQL).
Results
The therapeutic effect in observation group was better than that of control group (
P
＜0.05).The recurrence rates in observation group were lower than those in control group at 3 and 6 months after intervention(
P
＜0.05).There was no difference in ISQL score between the two groups before intervention (
P
＞0.05);while ISQL scores in observation group were higher than those in control group at 3 and 6 months after intervention,the differences were statistically significant(
P
＜0.05).
Conclusion
Family centered nursing can increase the therapeutic effect,reduce the recurrence rate,and improve the quality of life of children with NS.
2020 Vol. 27 (24): 213-215 [
Abstract
] (
26
)
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216
Application effect of individualized high-quality nursing intervention on post-traumatic limb fractures
YANG Wei
Objective
To explore the application effect of individualized high-quality nursing interventions on postoperative trauma and fracture of limbs.
Methods
Ninety patients with traumatic limb fractures who underwent surgical treatment in our hospital from September 2018 to September 2019 were selected as research subjects.They were divided into control group and observation group by random number table method,45 cases in each group.The control group received routine nursing care.The observation group received individualized high-quality nursing interventions,the improvement of patients′pain and their satisfaction with nursing care were compared.
Results
After nursing,the pain total relief rate in the observation group was higher than that in the control group,and the difference was statistically significant(
P
＜0.05).The incision healing in the observation group was better than that in the control group,and the difference was statistically significant(
P
＜0.05);the nursing total satisfaction of patients in the observation group was higher than that in the control group,and the difference was statistically significant(
P
＜0.05).
Conclusion
Individualized highquality nursing intervention can effectively reduce postoperative pain and improve patients′satisfaction with nursing.
2020 Vol. 27 (24): 216-218 [
Abstract
] (
24
)
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12
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219
Application effect of traditional Chinese medicine nursing intervention in patients with type 2 diabetes
ZHANGHui-zhu
Objective
To analyze the application effect of traditional Chinese medicine (TCM)nursing intervention in patients with type 2 diabetes (T2DM).
Methods
A total of 98 patients with T2DM treated in our hospital from June 2018 to July 2019 were selected.They were divided into control group and observation group according to the evenodd method,49 cases in each group.The control group received routine clinical nursing,the observation group was given TCM nursing intervention on the basis of routine nursing.The application effect of the two groups was compared.
Results
After nursing,the blood glucose indexes in observation group such as fasting blood glucose (Glu),glycated hemoglobin(HbA1c),2 h postprandial blood glucose(2 h PBG)were lower than those in the control group,the differences were statistically significant(
P
＜0.05);the quality of life such as treatment,physiological function,psychological/spiritual and social relationships was higher than that of the control group,and the scores of anxiety and depression were lower than those of the control group,and the differences were statistically significant(
P
＜0.05).
Conclusion
The use of TCM nursing intervention in patients with T2DM can reduce patients′blood glucose levels,improve their quality of life,and improve their psychological status.The clinical application value is higher.
2020 Vol. 27 (24): 219-221转225 [
Abstract
] (
26
)
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222
Application effect of personalized psychological nursing in patients with cholecystitis
FANG Yuan
Objective
To explore the clinical application effect of personalized psychological nursing in patients with cholecystitis.
Methods
A total of 80 patients with cholecystitis admitted to our hospital from January 2018 to June 2019 were selected as the research subjects.They were divided into the observation group and the control group according to the random number table method,40 cases in each group.In the control group,routine nursing was used,and in the observation group,personalized psychological nursing on the basis of routine nursing was adopted.The changes of the mental status scale in non-psychiatric settings (MSSNS)score before and after nursing and the knowledge of cholecystitis between the two groups were compared.
Results
There were no statistically significant differences in the MSSNSscores between the two groups before nursing(
P
＞0.05).After nursing,the MSSNSscores in the two groups were lower than those before nursing,and the MSSNS scores in the observation group after nursing were lower than those in the control group,with statistically significant differences(
P
＜0.05).The knowledge of cholecystitis cognition in the observation group was higher than that in the control group,and the difference was statistically significant(
P
＜0.05).
Conclusion
The clinical use of personalized psychological nursing in patients with cholecystitis is remarkable.
2020 Vol. 27 (24): 222-225 [
Abstract
] (
29
)
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226
Application effect of comprehensive nursing intervention in maxillofacial fracture reduction and rigid internal fixation
LIU Bo TONGLing ZHANGHui JIA Li-sha
Objective
To explore the application effect of comprehensive nursing intervention in the reduction and internal fixation of maxillofacial fractures.
Methods
The clinical data of 120 patients with maxillofacial fractures diagnosed and treated in our hospital from June 2017 to May 2019 were retrospectively analyzed.All patients underwent reduction and internal fixation surgery and were divided into control group and research group according to different nursing schemes,60 cases in each group.The control group applied routine nursing intervention,and the research group applied comprehensive nursing intervention,the nursing effect and subjective nursing experience difference between the two groups were compared.
Results
The excellent care rate of patients in the research group was higher(100.00%)than that of the control group (90.00%),the difference was statistically significant(
P
＜0.05);the subjective nursing experience score of the research group was higher than that of the control group,the difference was statistically significant(
P
＜0.05).
Conclusion
Comprehensive nursing intervention has a good effect in the sturdy internal fixation of maxillofacial fracture reduction.It can assist surgical treatment,achieve anatomical reduction of maxillofacial fracture,and maximize the occlusal relationship and subjective nursing experience.
2020 Vol. 27 (24): 226-228 [
Abstract
] (
26
)
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15
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229
Application of whole-course nursing in the mixed hemorrhoids treated with open-loop minimal invasion hemorrhoid anastomosis
LI Chao-qun
Objective
To explore the application effect of whole-course nursing in the mixed hemorrhoids treated with open-loop minimal invasion hemorrhoid anastomosis.
Methods
A total of 84 patients with mixed hemorrhoids admitted to our hospital from June 2017 to June 2019 were selected as research subjects.Those patients were all treated with open-loop minimal invasion hemorrhoid anastomosis.They were divided into two groups using balls in red and blue color,42 cases in each group.The control group received routine nursing,and the observation group received wholecourse nursing on that basis.The status of postoperative pain,the total incidence of complications,and the comfort level before and after nursing were compared between the two groups.
Results
The pain score of 24 hours after surgery in the observation group was (4.47±0.72)points,the pain score of 2 days after surgery was(3.86±0.71)points,the pain score of 5 days after surgery was(3.24±0.71)points and the pain score of 7 days after surgery was(2.69±0.57)points,lower than those of the control group,which were(5.29±0.65),(4.73±0.69),(3.92±0.69),(3.42±0.69)and(3.42±0.61)points,respectively(
P
＜0.05).The total incidence of complications in the observation group was 9.52%,lower than that of the control group accounting for 28.57% (
P
＜0.05).Before nursing,the comfort score was(69.31±10.48)points in the observation group,compared with(69.84±11.67)points in the control group,showing no significant difference(
P
＞0.05).The comfort score after nursing was(91.28±5.57)points in the observation group,higher than that of the control group,which was(83.37±6.49)points(
P
＜0.05).
Conclusion
The application of whole-course nursing after open-loop minimal invasion hemorrhoid anastomosis on patients with mixed hemorrhoids can effectively relieve patients′postoperative pain,reduce the incidence of complications,and improve patients′comfort level.
2020 Vol. 27 (24): 229-231 [
Abstract
] (
23
)
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11
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232
Application of evidence-based nursing on the elderly patients with type 2 diabetes
GAOShan-shan
Objective
To explore the application of evidence-based nursing in elderly patients with type 2 diabetes(T2DM).
Methods
A total of 92 elderly patients with T2DM admitted to our hospital from February 2018 to September 2019 were selected as the research objects.According to the random ball-touch method,they were divided into the control group (
n
=46)and the observation group (
n
=46).The control group adopted the conventional nursing method,while the observation group adopted the evidence-based nursing method.Blood glucose changes,total complication rate and total compliance were compared between the two groups.
Results
There were no significant differences in the fasting blood glucose and 2 h postprandial blood glucose before nursing between the two groups(
P
＞0.05).The fasting blood glucose and 2 h postprandial blood glucose of the observation group after nursing were lower than those of the control group,and the differences were statistically significant(
P
＜0.05);the blood glucose levels in the observation group after nursing were lower than those before nursing,the difference was statistically significant(
P
＜0.05).The total complication rate in the observation group was lower than that in the control group,the difference was statistically significant(
P
＜0.05);the total compliance of patients in the observation group was higher than that in the control group,and the difference was statistically significant(
P
＜0.05).
Conclusion
In elderly patients with T2DM evidence-based care can effectively control fasting blood glucose and 2 h postprandial blood glucose levels.It can also reduce complications and improve nursing compliance,which has clinical application value.
2020 Vol. 27 (24): 232-234 [
Abstract
] (
28
)
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Application effect of specific nursing on children with idiopathic thrombocytopenic purpura treated by drugs
YIN Ting
Objective
To explore the application effect of specific nursing on children with idiopathic thrombocytopenic purpura treated by drugs.
Methods
A total of 90 children with idiopathic thrombocytopenic purpura treated in our hospital from January 2018 to June 2019 were selected as the study objects,all of them were divided into control group and observation group according to the random number table method,with 45 cases in each group.All children were treated by Prednisone and Gamma Globulin,and children in control group were given routine nursing,children in observation group were given specific nursing.The change time of white blood cell count(PLT),total incidence of complications,medication compliance and total nursing satisfaction were compared between the two groups.
Results
The time for PLT to reach 50×10
9
/L,100×10
9
/L and peak value in the observation group were shorter than those in the control group,and the differences were statistically significant(
P
＜0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The compliance of children in the observation group was better than that of the control group,and the difference was statistically significant(
P
＜0.05).The total nursing satisfaction in the observation group was higher than that in the control group,and the difference was statistically significant(
P
＜0.05).
Conclusion
The effect of specific nursing for idiopathic thrombocytopenic purpura patients with drug treatment are clear,which can rapidly increase the white blood cell count,reduce complications,improve compliance and satisfaction,and is worthy of clinical application.
2020 Vol. 27 (24): 235-237转241 [
Abstract
] (
24
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238
Application effect of psychological nursing intervention and health education in patients with coronary heart disease
LIANGHong-yan
Objective
To explore the effect of psychological nursing intervention and health education in patients with coronary heart disease.
Methods
A total of 84 patients with coronary heart disease admitted to our hospital from January 2018 to October 2019 were selected as the research objects,and were divided into control group and observation group according to the odd-even number method,with 42 cases in each group.The control group used conventional nursing care,and the observation group used psychological nursing intervention and health education,the quality of life and psychological status before and after nursing were compared between the two groups.
Results
After the intervention,the scores of various indicators of the quality of life in the observation group were higher than those in the control group,and the differences were statistically significant(
P
＜0.05);the anxiety and depression scores after the intervention in the observation group were lower than those in the control group,and the differences were statistically significant(
P
＜0.05).
Conclusion
The application of psychological nursing intervention and health education in patients with coronary heart disease can improve their quality of life,reduce anxiety and depression,and enable them to obtain a good psychological state,the clinical application effect is reliable.
2020 Vol. 27 (24): 238-241 [
Abstract
] (
27
)
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12
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242
Application of unaccompanied nursing measures in long-term hospitalized patients with schizophrenia
WU Ya-nan
Objective
To investigate the overall effect of unaccompanied nursing measures in long-term hospitalized patients with schizophrenia.
Methods
From September 2017 to September 2018,70 cases of long-term hospitalized patients with schizophrenia in our hospital were selected as research subjects and divided into the control group(35 cases)and the observation group(35 cases)according to the principle of the random method.The control group carried out routine nursing measures,and the observation group carried out unaccompanied nursing measures,which included comprehensive evaluation,life guidance,drug guidance,psychological care and social support.The incidence of all kinds of risk events and the nursing effect were compared between the two groups.
Results
The total incidence of risk events during the nursing period of the observation group was 2.86%,which was lower than the 22.86%of the control group,the difference was statistically significant(
P
＜0.05).After nursing,the negative symptoms,positive symptoms scores and general psychopathology score of the observation group were lower than those of the control group,the total positive factors score of the nurses′observation scale for inpatient evaluation (NOISE-30)was higher than that of the control group,and the quality of life comprehensive assessment questionnaire(GQLI)score was higher than that of the control group,the differences were statistically significant(
P
＜0.05).
Conclusion
The nursing measures for long-term inpatients with schizophrenia can not only reduce the incidence of various risk events,but also enhance the safety during hospitalization,it can also significantly improve patients′disease symptoms,social skills and quality of life,with significant nursing effect and high application value.
2020 Vol. 27 (24): 242-245转249 [
Abstract
] (
26
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Application effect of continuous nursing in patients with hemiplegia after cerebral infarction
WANG Xin
Objective
To explore the application effect of continuous nursing in patients with hemiplegia after cerebral infarction.
Methods
A total of 75 patients with hemiplegia after cerebral infarction admitted to our hospital from May 2017 to May 2018 were selected as the research objects.They were divided into the reference group and the experimental group according to the random number table method,and 38 patients in the reference group were given routine nursing intervention,37 patients in the experimental group were given routine nursing combined with continuous nursing intervention.The nursing compliance of the two groups of patients,as well as the improvement of daily life function,motor function and quality of life of the two groups before and after nursing were compared.
Results
The excellent and good rate of nursing compliance in the experimental group (94.59%)was higher than that of the reference group(76.32%),and the difference was statistically significant(
P
＜0.05).Before nursing,there were no significant differences in the activity of daily living scale(ADL)and fugl-meyer assessment(FMA)scores of patients in the two groups(
P
＞0.05);after the nursing,the ADL and FMA scores of the experimental group were higher than those of the reference group,the differences were statistically significant(
P
＜0.05).The quality of life scale (SF-36)score of the patients in the experimental group after nursing was higher than that of the reference group,and the difference was statistically significant(
P
＜0.05).
Conclusion
The practical effect of applying continuous nursing in the treatment of hemiplegic patients after cerebral infarction is more prominent and worthy of application.
2020 Vol. 27 (24): 246-249 [
Abstract
] (
29
)
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Application value of humanized nursing in the elderly patients with glaucoma
ZHAOYan
Objective
To explore the application value of humanized nursing in elderly glaucoma patients.
Methods
Eighty elderly patients with glaucoma (≥60 years old)who were admitted to the department of ophthalmology of our hospital from February 2018 to February 2019 were selected as the research subjects.They were divided into control group (40 cases)and observation group (40 cases)according to the random number table method.The control group carried out traditional nursing,and the observation group implemented humanized nursing intervention on this basis.The total incidence of postoperative complications,quality of life score and nursing satisfaction were compared between the two groups.
Results
The total incidence of postoperative complications in the observation group (5.00%)was lower than that in the control group(20.00%),with statistically significant difference(
P
＜0.05).The scores of physical function,mental health,emotional status,social function,health status and other quality of life in the observation group were all higher than those in the control group,with statistically significant differences(
P＜
0.05).The total nursing satisfaction of patients in the observation group(92.50%)was higher than that of the control group(75.00%),and the difference was statistically significant(
P
＜0.05).
Conclusion
For elderly glaucoma patients,humanized nursing intervention can reduce complications,improve quality of life,improve nursing satisfaction,and have outstanding clinical application value.
2020 Vol. 27 (24): 250-252 [
Abstract
] (
29
)
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