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| Application effect of Petrolatum gauze block combined with Vitamin B 12 Mixture Solution in dressing change for second-degree radiation skin injury |
| LIU Xiao-yun WEN Sheng-ying ZENG Ying-ting |
| The Third Department of Radiotherapy,Ganzhou Cancer Hospital,Jiangxi Province,Ganzhou 341000,China |
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Abstract Objective To explore the application effect of Petrolatum gauze block combined with Vitamin B12 Mixture Solution in dressing change for second-degree radiation skin injury.Methods From January to November 2019,90 patients with second-degree radiation skin injury caused by intensity-modulated radiotherapy were selected as subjects and divided into control group and observation group by random number table method,with 45 cases in each group.The control group used sterile gauze block soaked with Vitamin B12 Mixture Solution for wet compress,and the observation group was added with Petrolatum gauze block on the basis of the control group.The clinical efficacy,pain scores,and epidermal cytokine(vascular endothelial growth factor[VEGF],transforming growth factor-β[TGF-β1],basic fibroblast growth factor[bFGF])levels before and after treatment were compared between the two groups of patients after treatment]expression.Results After treatment,the total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).After treatment for 15 and 30 minutes,the numerical grading method (NRS)pain score of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).After treatment for 3 days,the levels of VEGF,TGF-β1 and bFGF in the observation group were all higher than those in the control group,with statistically significant differences(P＜0.05).Conclusion Petrolatum gauze block combined with Vitamin B12 Mixture Solution has a good application effect in the second-degree radiation skin injury dressing change,which can effectively relieve the pain of patients,promote skin tissue recovery,and regulate the expression of epidermal cytokines.
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Received: 31 March 2020
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| [1] |
王楠.两种皮肤防护剂防治头颈部恶性肿瘤患者放射性皮肤损伤疗效对比[J].中国烧伤创疡杂志，2019，31（6）：391-393.
|
| [2] |
朱月英，唐艳华.聚酯泡沫敷料联合TDP照射治疗放射性皮肤损伤的效果[J].中西医结合护理（中英文），2019，5（4）：102-104.
|
| [3] |
尹成国，赵亮，高广辉，等.比较3M透明敷贴与凡士林纱布治疗指端缺损的临床疗效[J].实用手外科杂志，2019，33（3）：283-286.
|
| [4] |
张立辉.烧伤止痛膏治疗烧伤创面的临床疗效评价[J].中国社区医师，2018，34（19）：110-111.
|
| [5] |
任跃君，任俏丽，李洁.壳聚糖医用功能性敷料预防放射性皮肤损伤临床效果观察[J].临床医药实践，2019，28（9）：702-704.
|
| [6] |
诸晓璇，郑美春，覃惠英.自黏性软聚硅酮薄膜敷料用于防治放射性皮肤损伤效果的Meta分析[J].中华现代护理杂志，2019，25（31）：3997-4002.
|
| [7] |
李华云.凡士林纱布联合美宝湿润烧伤膏在天疱疮患者皮损护理中的应用[J].中西医结合护理（中英文），2019，5（5）：112-113.
|
| [8] |
于海荣.医用硅酮凝胶膏联合凡士林纱敷药在Ⅱ～Ⅲ期压疮老年患者中的应用[J].国际医药卫生导报，2016，22（18）：2884-2887.
|
| [9] |
梁淑玲，李翠珠，梁艳红，等.银离子联合泡沫敷料在乳腺癌放射性皮炎的护理路径探究[J].泰山医学院学报，2018，39（8）：954-955.
|
| [10] |
许湘华，谌永毅，周莲清.医用胶粘剂相关性皮肤损伤的研究进展[J].解放军护理杂志，2017，34（3）：51-54.
|
| [11] |
朱小妹，李旭英，刘华云，等.湿性愈合理念在急性放射性皮肤损伤患者中的疗效观察[J].护士进修杂志，2019，34（16）：1515-1518.
|
| [12] |
闫美玲，谢莹莹，王蓉蓉.药用辅料凡士林的研究现状与应用[J].海峡药学，2018，30（9）：9-15.
|
| [13] |
Hüging M，Biedermann T，Sobrio M，etal.The Effect of Wound Dressings on a Bio-Engineered Human Dermo-Epidermal Skin Substitute in a Rat Model[J].JBurn Care Res，2017，38（6）：1.
|
| [14] |
陈彩虹，黄家龙.水胶体敷料溃疡贴与碘伏治疗Ⅲ期压力性损伤的效果观察[J].中国卫生标准管理，2019，10（14）：68-70.
|
| [15] |
兰桂香，陈雯，欧阳良美.改良使用凡士林纱块在基层医院气管切开护理中的应用研究[J].基层医学论坛，2018，22（9）：1156-1158.
|
| [16] |
卢安阳.纳米银抗菌敷料对比凡士林敷料治疗老年Ⅱ度烧伤的临床应用分析[J].健康之路，2018，18（11）：174-175.
|
| [17] |
李胜，杜江.任海霞.2%聚维酮碘凡士林纱布在预防阑尾切除术后切口感染中的应用研究[J].安徽医药，2019，23（1）：155-157.
|
| [18] |
邝广梅，陈瀚熙，黄伟玲，等.微动力负压护创敷料在深Ⅱ度烧伤创面中应用效果观察及护理[J].现代临床护理，2019，19（6）：17-20.
|
| [19] |
邸瑞玲，张丽娜.凡士林纱条配合膨胀海绵填塞治疗难治性鼻出血患者耐受性的效果观察[J].医学信息，2017，30（10）：46-47.
|
| [20] |
黄晶.凡士林纱布辅助治疗重症天疱疮患者的护理方法分析[J].实用临床护理学电子杂志，2019，4（28）：56-66.
|
|
|
|
