AbstractObjective To investigate the overall effect of unaccompanied nursing measures in long-term hospitalized patients with schizophrenia.Methods From September 2017 to September 2018,70 cases of long-term hospitalized patients with schizophrenia in our hospital were selected as research subjects and divided into the control group(35 cases)and the observation group(35 cases)according to the principle of the random method.The control group carried out routine nursing measures,and the observation group carried out unaccompanied nursing measures,which included comprehensive evaluation,life guidance,drug guidance,psychological care and social support.The incidence of all kinds of risk events and the nursing effect were compared between the two groups.Results The total incidence of risk events during the nursing period of the observation group was 2.86%,which was lower than the 22.86%of the control group,the difference was statistically significant(P<0.05).After nursing,the negative symptoms,positive symptoms scores and general psychopathology score of the observation group were lower than those of the control group,the total positive factors score of the nurses′observation scale for inpatient evaluation (NOISE-30)was higher than that of the control group,and the quality of life comprehensive assessment questionnaire(GQLI)score was higher than that of the control group,the differences were statistically significant(P<0.05).Conclusion The nursing measures for long-term inpatients with schizophrenia can not only reduce the incidence of various risk events,but also enhance the safety during hospitalization,it can also significantly improve patients′disease symptoms,social skills and quality of life,with significant nursing effect and high application value.