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2020 Vol. 27, No. 30
Published: 2020-10-28
 
 
4 Clinical value of Bovine Pulmonary Surfactant combined with nasal-continuous positive airway pressure ventilation in the treatment of neonatal respiratory distress syndrome
LONG Yu-yu
Objective To analyze the clinical value of Bovine Pulmonary Surfactant combined with nasal-continuous positive airway pressure ventilation (NCPAP) in the treatment of neonatal respiratory distress syndrome (NRDS).Methods From March 2018 to October 2019,88 cases of NRDS diagnosed and treated in our department were randomly divided into the observation group and the control group according to the envelope method,44 cases in each group.Both groups were treated with NCPAP,and the observation group was treated with Bovine Pulmonary Surfactant in addition.The clinical symptom improvement,the blood gas analysis index,ventilator ventilation time,oxygen therapy time,hospitalization time and the incidence of complications between the two groups were compared.Results The disappearance time of cyanosis and dyspnea in the observation group was shorter than that in the control group,the difference was statistically significant (P<0.05).The blood gas analysis indexes both improved in the two groups after treatment,and the blood oxygen partial pressure of the observation group was higher than that of the control group,and the partial pressure of carbon dioxide was lower than that of the control group,the differences were statistically significant (P<0.05).The ventilator ventilation time,oxygen therapy time and hospitalization time of the observation group were shorter than those of the control group,the differences were statistically significant (P<0.05).There was no significant difference in the total incidence of complications between the two groups (P>0.05).Conclusion Compared with using NCPAP alone,Bovine Pulmonary Surfactant combined with NCPAP is more effective in the treatment of NRDS,promoting the earlier elimination of clinical symptoms,improving blood gas analysis results,shortening ventilation time,and reducing the risk of complications.So it is worth promoting in clinical application.
2020 Vol. 27 (30): 4-7 [Abstract] ( 23 ) HTML (36 KB)  PDF  (0 KB)  ( 9 )
8 Effect of mindfulness-based stress reduction assisted emotional management on quality of life,anxiety and depression in patients with inflammatory bowel disease
LING Yan; LU Wen-ling; LI Xi
Objective To investigate the effect of mindfulness-based stress reduction (MBSR) assisted emotional management on quality of life,anxiety and depression in patients with inflammatory bowel disease (IBD).Methods A total of 155 patients with IBD admitted to our hospital from March 2018 to March 2019 were selected as the research objects by convenient sampling method and randomly divided into the control group (78 cases) and the observation group (77 cases) by coin toss method.The control group was given routine education,and the observation group was instructed to learn MBSR assisted emotional management to deal with negative emotions on the basis of the control group.The scores of self-rating anxiety scale (SAS),self-rating depression scale (SDS) and IBD questionnaire (IBDQ) were compared between the two groups at admission and 24 weeks after discharge.Results There were no statistically significant differences in SAS,SDS and IBDQ scores between the two groups at admission (P>0.05).After 24 weeks of discharge,the SAS,SDS scores of the observation group were higher than those at admission,the IBDQ score was lower than that at admission,and the differences were statistically significant (P<0.05).After 24 weeks of discharge,the SAS,SDS scores of the observation group were higher than those of the control group,the IBDQ score was lower than that of the control group,and the differences were statistically significant (P<0.05).Conclusion The MBSR assisted emotional management can improve the mental health of patients with IBD and improve their quality of life.
2020 Vol. 27 (30): 8-12 [Abstract] ( 31 ) HTML (43 KB)  PDF  (0 KB)  ( 11 )
13 Comparative analysis of clinical characteristics of neonates with purulent meningitis caused by different pathogens
CHEN Zhi-qing; ZHOU Dan ;LIN Fang-fang
Objective To study the clinical characteristics,pathogen distribution,treatment and outcome of purulent meningitis in neonates in order to provide the guide for early diagnosis and appropriate treatment.Methods The case data of 134 newborn children with purulent meningitis who were admitted to Fujian Maternity and Child Health Hospital from January 1,2014 to December 31,2016 were retrospectively analyzed.According to the results of blood culture or cerebrospinal fluid (CSF) culture,the subjects were divided into the Streptococcus agalactiae (GBS) group (15 cases),the other bacteria group (14 cases),and the unknown pathogen group (105 caces),and the clinical characteristics of each group were compared.Results The main clinical manifestations of purulent meningitis were fever,shortness of breath and jaundice,fever was the most common symptom.The positive rate of blood and cerebrospinal fluid culture was low,mainly GBS and Escherichia coli.C-reactive protein (CRP) levels in the GBS group and the other bacteria group were higher than those in the unknown pathogen group,and the differences were statistically significant (P＜0.05).The cerebrospinal fluid white blood cell counts of the other bacteria group and the GBS group were higher than those of the unknown pathogen group,the percentage of CSF polykaryotic cells in the GBS group was higher than that in the other bacteria group and the unknown pathogen group,and the differences were statistically significant (P＜0.05).There were 30 cases with CSF protein exceeding 1.88 g/L,among whom 13 cases had complications.A total of 83 cases were cured,44 cases were improved,2 cases were complicated with subdural effusion for further treatment by neurosurgery,and 5 cases were abandoned due to severe complications.Conclusion The clinical manifestations of neonatal purulent meningitis are lack of specificity,fever is the most common symptom.The main pathogens are GBS and Escherichia coli,and GBS infection should be considered if CRP,the percentage of leukocytes and polynuclear cells in CSF increase significantly.
2020 Vol. 27 (30): 13-17 [Abstract] ( 29 ) HTML (44 KB)  PDF  (0 KB)  ( 10 )
18 Protective effect of Allopurinol on renal injury in rats with chronic intermittent hypoxia
DU Yi; LIANG-Shun; WEI Yu-ting; KE Jian-ting; PEI Xue-feng
 Objective To study the protective effect of allopurinol (ALLO) on renal injury in rats with chronic intermittent hypoxia (CIH).Methods A total of 40 male Wistar rats were randomly divided into the normal control group(10 rats) and the model group,the rats in the model group were divided into the model control group (10 rats),the low dose of ALLO group (20 mg/[kg·d],10 rats) and the high dose of ALLO group (40 mg/[kg·d],10 rats).The CIH mode was established in the model group,which were given gavage for 14 days.The levels of cystatin C (Cys-C) and vascular endothelial growth factor (VEGF) were measured in rats venous serum before and after treatment.The pathological changes of renal tissue were observed under light microscope.The expression of xanthine oxidase (XO) protein was detected by Western blot.The levels of superoxide dismutase (SOD),malondialdehyde (MDA) were detected by renal tissue homogenate.Results The serum Cys-C,VEGF levels and renal tissue MDA,XO expression level in the normal control group were higher than those in the model control group,the SOD level in the normal control group was lower than that in the model control group,the differences were statistically significant (P＜0.01).The serum Cys-C,VEGF levels and renal tissue MDA,XO expression levels of the model control group were higher than those of the low dose of ALLO group and the high dose of ALLO group after 2 weeks of modeling treatment,and renal tissue SOD level of the low dose of ALLO group was lower than that of the high dose of ALLO group (P＜0.01).The MDA level of the high dose of ALLO group was lower than that of the model control group and the low dose of ALLO group,and the SOD level of the high dose of ALLO group was higher than that of the model control group and the low dose of ALLO group (P＜0.05).There were no significant differences in the levels of serum CysC,VEGF,XO renal tissue expression between the high dose of ALLO group and the low dose of ALLO group (P＞0.05).Renal tissue MDA levels were correlated with serum VGEF (r=0.65,P<0.05).The renal HE staining in the model control group showed significant glomerular volume increase,glomerular mesangial cells and matrix hyperplasia,and some glomeruli showed focal segmental sclerosis.Vacuolar-like degeneration was found in renal tubular epithelial cells than in the high dose of ALLO group and the low dose of ALLO group.Conclusion Renal injury in CIH rats is associated with oxidative stress and VGEF.The effect of ALLO on oxidative stress in CIH rats is more significant with the increase of dose,which inhibits serum VGEF in CIH rats.ALLO attenuates renal injury in CIH rats through inhibition of oxidative stress response and VGEF.
2020 Vol. 27 (30): 18-22 [Abstract] ( 25 ) HTML (44 KB)  PDF  (0 KB)  ( 13 )
23 Research progress of acoustic radiation force impulse in the differential diagnosis of benign and malignant breast lesions
XU Shan-shan; SUN Jian-wei
In recent years,the proportion of patients with breast disease has been increasing year by year.Early detection and early treatment of breast cancer can help improve the 5-year survival rate of breast cancer and improve the prognosis of patients.At present,acoustic radiation force impulse (ARFI) provides new diagnosis and treatment ideas for breast diseases.ARFI is a new type of ultrasound imaging technology to tissue hardness evaluation,which includes virtual touch tissue quantification (VTQ),virtual touch tissue imaging (VTI),and a combination of both virtual touch tissue imaging quantification (VTIQ).These three techniques are widely and maturely applied in the differential diagnosis of breast benign and malignant diseases.The progress of clinical research on this technique for differential diagnosis of breast benign and malignant diseases is reviewed in this article.
2020 Vol. 27 (30): 23-26转30 [Abstract] ( 26 ) HTML (43 KB)  PDF  (0 KB)  ( 8 )
27 Research progress of serum interleukin-33 in central nervous system diseases
CHEN Zhen-lei ;QIN Xin-yue
Interleukin-33 (IL-33),as an inflammatory factor,plays an important role in diseases of cardiovascular system,digestive system,respiratory system,tumors and other diseases,especially in the central nervous system,which is the current hot spot.However,the function of IL-33 in some diseases of central nervous system remains controversial.This review explained the pathogenesis,latest research advances,the potential prediction and therapeutic value of IL-33 in kinds of central nervous system diseases (4 types of intracranial infection,2 kinds of cerebrovascular disease,cognitive impairment,depression and glioma were included) through consulting a lot of literature.
2020 Vol. 27 (30): 27-30 [Abstract] ( 31 ) HTML (38 KB)  PDF  (0 KB)  ( 9 )
31 Influence and clinical significance of Thymalfasin on T-lymphocyte subsets of patients with silicosis combined with tuberculosis
WU Bo; HE Dan;ZHANG Yi;TANG Hai-yun; LIU Xi-dong
Objective To investigate the influence and clinical significance of Thymalfasin on T-lymphocyte subsets of patients with silicosis combined with tuberculosis.Methods A total of 60 patients with silicosis combined with tuberculosis in General Hospital of Pingxiang Mining Group Co.,Ltd.were selected as the research subjects.They were divided into two groups according to random number table method,30 cases in each group.The control group was given routine chemotherapy regimen,and research group added Thymalfasin.The negative conversion ratio at different time after treatment were compared between two groups.After treatment for 6 months,the efficacy,CD4+,CD8+,CD4+/CD8+,adverse reactions were compared.Results After treatment for 3， 6 and 12 months,the negative conversion ratio of research group was higher than that of control group;after treatment for 6 months,the cure rate of research group was higher than that of control group,the total incidence of adverse reactions in research group was lower than that in control group,the differences were statistically significant (P<0.05).There were no statistical differences in the levels of CD4+,CD4+/CD8+ and CD8+ between two groups before treatment (P＞0.05);after treatment for 6 months,the levels of CD4+ and CD4+/CD8+ in research group were higher than those in control group,and the level of CD8+ in research group was lower than that in control group,the differences were statistically significant (P<0.05).Conclusion Thymalfasin and routine chemotherapy in treatment of silicosis combined with tuberculosis has significant effect,it can increase negative conversion ratio and the levels of T-lymphocyte subsets,which has higher safety.
2020 Vol. 27 (30): 31-33 [Abstract] ( 33 ) HTML (38 KB)  PDF  (0 KB)  ( 8 )
34 Application of thromboelastogram in the evaluation of blood transfusion in patients with craniocerebral injury
LI Ji-hong ;JIANG Wei-chun; ZHANG Yu-ping ;HU Kai ;ZHANG Zhi-ming ;TU Ya-ting
 Objective To investigate the thromboelastogram (TEG) in the evaluation of blood transfusion in patients with craniocerebral injury.Methods A total of 70 patients with craniocerebral injury who were admitted to our hospital from February 2017 to June 2019 were selected,and they were divided into control group (n=35) and observation group(n=35) according to random number table method.Two groups underwent craniotomy evacuation of hematoma.The control group was supplemented with blood products based on clinical experience and blood gas analysis results during the operation,and the observation group was supplemented with blood products based on TEG test results.The intraoperative blood transfusion volume,perioperative indexes,and postoperative situations were compared between the two groups.Results The intraoperative suspended red blood cell,platelet,fresh frozen plasma and cryoprecipitation transfusion volume in the observation group were less than those in the control group (P<0.05).There was no statistically significant difference in the operation time between the two groups (P＞0.05).The intraoperative bleeding volume,postoperative 6 and 24 h drainage volume in the observation group were less than those in the control group,and the differences were statistically significant (P<0.05).The rate of second craniotomy in the observation group was lower than that in the control group (P<0.05).There was no statistically significant difference in the death between the two groups within 4 weeks (P＞0.05).Conclusion The application effect of TEG in patients with craniocerebral injury is significant,it can reduce intraoperative blood transfusion volume,intraoperative bleeding volume and postoperative 24 h drainage volume,and decrease the incidence of second craniotomy,which has certain guiding effect in the clinical rational use of blood products.
2020 Vol. 27 (30): 34-36 [Abstract] ( 26 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
37 Expression and significance of HER4 in gliomas of different pathological grades
ZHANG Xin-juan; SUN Long;WANG Hai-feng;JIANG Xu-guang
Objective To study the expression of HER4 in gliomas of different pathological grades.Methods A total of 88 cases of primary gliomas which were removed surgically in Linyi Central Hospital from January 2008 to December 2009 were selected and 14 cases of normal brain tissues from patients with brain injury underwent craniotomy and decompression as control.The expression level of HER4 in normal brain and glioma tissues of different pathological grades was detected by immunohistochemistry.Results The positive expression of HER4 was mainly localized in cytoplasm and nucleus.HER4 highly expressed in gliomas compared with normal brain tissue (P<0.05).The expression of HER4 in low-grade gliomas was higher than that in normal brain tissues (P<0.05),while that in high-grade gliomas was higher than that in low-grade gliomas,the differences were statistically significant (P<0.05).Conclusion HER4 plays an important regulatory role in the occurrence and development of gliomas.HER4 can be used as an important biological index to evaluate the malignant degree of gliomas.At the same time,HER4 can also be used as a new target for gliomas treatment.
2020 Vol. 27 (30): 37-39 [Abstract] ( 24 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
40 Effect of uric acid therapy on renal function in elderly patients with chronic kidney disease complicated with hyperuricemia
CAI Li ;CHEN Yao ;WU Ya-li ;LI Peng; ZHU Wen; LE Mei-cheng
Objective To investigate the effect of uric acid lowering therapy on renal function in elderly patients with 2-5 stage chronic kidney disease with hyperuricemia.Methods According to the patient′s glomerular filtration rate(GFR),110 patients with stage 2 to 5 chronic kidney disease and hyperuricemia who were treated in our hospital from January 2019 to January 2020 were selected and divided into group A (74 cases),GFR value was between 30-89 ml/min(60-89 ml/min was stage 2,30-59 ml/min was stage 3) and group B (36 cases),GFR value was between 0-29 ml/min(15-29 ml/min was 4 stages,<15 ml/min was 5 stages,according to GFR value.Both groups were treated with Febuxostat.The blood uric acid (SUA) attainment rate was compared between the two groups.the changes in renal kinetic energy (blood creatinine [SCr],SUA,urea nitrogen [BUN]) before and after treatment and adverse drug reactions in all patients were compared between the two groups Results After 6 months of treatment,the uric acid lowering compliance rate of both groups was above 90% (P＞0.05);after treatment,the levels of SCr,SUA,and BUN at each time point in groups A and B decreased,and the improvement effect of group A was better (P<0.05).Conclusion Febuxostat has a good effect on the treatment of stage 2-3 chronic kidney disease with hyperuricemia,can effectively improve renal function,delay the progression of the disease,and has high safety and is worth promoting.
2020 Vol. 27 (30): 40-42转46 [Abstract] ( 25 ) HTML (33 KB)  PDF  (0 KB)  ( 11 )
43 Application effect of intestinal probiotics in the treatment of acute exacerbation of chronic obstructive pulmonary disease patients with respiratory failure
DU Jun-yi;YANG Chao; SHAO Jing; LI Hang; YANG Li-juan; ZHANG Hua-qing; CHEN Min
Objective To investigate the therapeutic value of intestinal probiotics in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with respiratory failure.Methods From May to October 201960 AECOPD patients with respiratory failure in Canmei Hospital of Kunming First People′s Hospital were selected.According to random number table methodthey were divided into control group and treatment group30 cases in each group.The control group was treated with routine treatmentand the treatment group was treated with routine treatment and intestinal live bacteria preparation.After 2 weeks of treatmentthe differences in inflammatory index and nutritional status before and after treatment were compared between the two groups.Results There were no significant differences in white blood cells (WBC)neutrophil ratio (N%) and C-reactive protein (CRP) between the treatment group and the control group before treatment (P＞0.05).The WBC after treatment in the treatment group was lower than that in the control group (P<0.05)but there were no significant differences in N%CRP between the two groups after treatment (P＞0.05).The WBCN%CRP after treatment of the two groups were lower than before treatmentand the differences were statistically significant (P<0.05).There were no significant differences in serum albumin (ALB) and prealbumin (PA) between two groups before treatment (P＞0.05).The serum ALB and PA after treatment in the treatment group were higher than those before treatment (P<0.05),the ALB after treatment in the control group was lower than that before treatmentand the differences were statistically significant (P<0.05)while the difference in the PA between after treatment and before treatment was not statistically significant (P＞0.05).Conclusion The use of intestinal live bacterial preparations in patients with AECOPD with respiratory failure can reduce inflammation and improve nutritional statusthereby improving prognosis.
2020 Vol. 27 (30): 43-46 [Abstract] ( 28 ) HTML (34 KB)  PDF  (0 KB)  ( 9 )
47 Effect of non-invasive ventilator in the treatment of chronic obstructive pulmonary disease with sleep apnea hypopnea syndrome
CHEN Shao-shan; LI Ju-heng; LIN Shi-jun
 Objective To evaluate the effect of noninvasive ventilator in the treatment of chronic obstructive pulmonary disease (COPD) with sleep apnea hypopnea syndrome (SAHS).Methods A total of 70 patients with COPD and SAHS admitted to our hospital from October 2014 to October 2019 were selected as the research objects.They were divided into observation group (n=35) and control group (n=35) according to method of drawing lots for random grouping.The observation group was treated with non-invasive ventilator,while the control group was treated with conventional therapy.The values of percutaneous oxygenation (SaO2),bicarbonate (HCO3-),pH,partial pressure of carbon dioxide (PCO2)oxygen partial pressure (PO2),forced expiratory volume in first second (FEV1)/forced vital capacity (FVC),ratio of FEV1 to predicted value and therapeutic effect were compared between the two groups.Results There were statistically significant differences in the observation group before and after treatment in SaO2,blood HCO3-,PCO2,and PO2 (P<0.05);there was no significant difference in pH before and after treatment (P＞0.05);there was significant difference in SaO2 before and after treatment in the control group (P<0.05),there were significant differences after treatment in blood HCO3-,pH,PCO2,and PO2 compared with before treatment (P<0.05).Patients in the observation group after treatment,SaO2,blood HCO3-,pH,PCO2,and PO2 were better than those in the control group,and the differences were statistically significant (P<0.05).The comparison of FEV1/FVC,FEV1% before treatment between the two groups was not statistically significant (P＞0.05);in the observation group after treatment,the predicted values of FEV1/FVC and FEV1% were higher than those in the control group,and the differences were statistically significant (P<0.05).The peak inspiratory pressure and tidal volume in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).The total effective rate in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion The non-invasive ventilator therapy for COPD with SAHS can significantly improve the arterial blood gas,pulmonary function and mechanical ventilation parameters of the patients,which has good application effect and promising development.
2020 Vol. 27 (30): 47-50 [Abstract] ( 23 ) HTML (48 KB)  PDF  (0 KB)  ( 9 )
51 Clinical value of transvaginal high-frequency color ultrasound in the diagnosis of endometrial lesions
ZHANG Yu-fei
 Objective To explore the clinical value of transvaginal high-frequency ultrasound in the diagnosis of endometrial lesions.Methods A total of 88 patients suspected with endometrial lesions admitted to our hospital from January 2016 to June 2019 were selected.The patients were subjected to abdominal B-ultrasound,transvaginal high-frequency color ultrasound and pathological examination.Taking the results of pathological diagnosis as golden standard,the concordance rates of the diagnosis of abdominal B-ultrasound and high-frequency color ultrasound with the diagnosis of pathological examination were analyzed and diagnostic value of the two methods was evaluated.Results The concordance rate of transvaginal high-frequency color ultrasound diagnosis was higher than that of the abdominal Bultrasound diagnosis (P<0.05) and had no significant difference from the pathological examination results (P＞0.05).The specificity of abdominal B-ultrasound in the diagnosis of endometrial lesions was 73.7% (14/19),the accuracy of that was 69.3% (61/88),and the sensitivity was 68.1% (47/69).The specificity of transvaginal high-frequency color ultrasound diagnosis of endometrial lesions was 78.9% (15/19),the accuracy of that was 86.4% (76/88),and the sensitivity was 88.4% (61/69).The specificity,accuracy rate and sensitivity of transvaginal high-frequency color ultrasound diagnosis of endometrial lesions were higher than those of the abdominal B-ultrasound diagnosis,the differences were statistically significant (P<0.05).Conclusion Compared with abdominal B-ultrasound,transvaginal high-frequency ultrasound has much higher diagnostic specificity,accuracy and sensitivity in the diagnosis of patients with endometrial lesions,which has high diagnostic value.Meanwhile,transvaginal high-frequency color ultrasound is non-invasive,easy to operate and economic,which can provide effective treatment basis for clinical treatment.Therefore,in the clinical treatment of patients with endometrial lesions,transvaginal high-frequency ultrasound diagnosis should be further promoted and applied.
2020 Vol. 27 (30): 51-53 [Abstract] ( 21 ) HTML (32 KB)  PDF  (0 KB)  ( 7 )
54 Impact of cognitive function training on motor function and daily living ability for elderly cerebral infarction patients
LI Dong
Objective To analyze the impact of cognitive function training on motor function and daily living ability for elderly cerebral infarction (CVA) patients.Methods A total of 60 elderly CVA patients from January 2017 to January 2019 treated in our hospital were selected as the research objects.They were divided into control group (n=30) and study group (n=30) according to random number table method.The control group took the conventional drug therapy and rehabilitation training;on the basis,the study group took the cognitive function training.Before intervention,after 6 and 12 weeks of intervention,patient′s cognitive function,motor function and daily living ability were appraised through Montreal cognitive assessment (MoCA),mini-mental state examination (MMSE),Fugl-Meyer assessment of motor function (FMA),Berg balance scale (BBS) and Barthel index (BI).Results Before intervention,MoCA,MMSE,FMA,BBS and BI scores between two groups were not significantly different (P＞0.05);after 6 and 12 weeks of intervention,MoCA,MMSE,FMA,BBS,BI scores of two groups were higher than those before intervention,and MoCA,MMSE,FMA,BBS and BI scores in the study group were higher than those in the control group,with statistical differences (P<0.05).Conclusion The conventional rehabilitation training combined with cognitive function training can delay or control the progression of cognitive disorder to improve patient′s motor function,daily living ability,and quality of life.Its application has broad prospects.
2020 Vol. 27 (30): 54-56转60 [Abstract] ( 20 ) HTML (33 KB)  PDF  (0 KB)  ( 9 )
57 Application effect of health education combined with exercise rehabilitation in seven steps after PCI in patients with acute myocardial infarction and its effect on quality of life
HAO Xiao-xi
 Objective To explore the application effect of health education combined with seven steps of exercise rehabilitation on the quality of life of patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI).Methods A total of 100 patients with AMI who were admitted to our hospital after PCI from March 2018 to March 2019 were selected and divided into two groups according to the principle of random control group,50 in each group.The patients in the control group were given seven steps of exercise rehabilitation after PCI.The patients in the experimental group were given health education on the basis of the control group.The clinical effect,quality of life scale (SF-36) score,left ventricular ejection fraction (LVEF),stent restenosis,revascularization and death were compared between the two groups.Results After treatment,the total effective rate in the experimental group was higher than that in the control group,the difference was statistically significant (P<0.05).There was no significant difference in SF-36 score between the two groups before treatment (P＞0.05).The scores of SF-36 items in the two groups were higher after treatment than those before treatment,the scores of SF-36 items in the experimental group were higher than those in the control group,and the differences were statistically significant (P<0.05).There was no significant difference in LVEF value between the two groups before treatment (P＞0.05).The LVEF values of the two groups were higher after treatment than those before treatment,the LVEF value of the experimental group was higher than that of the control group,and the differences were statistically significant (P<0.05).The incidence of adverse events such as death,revascularization and stent restenosis in the experimental group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion The seven steps of health education combined with exercise rehabilitation for patients with AMI after PCI has better clinical effect and can improve the quality of life of patients,which is worthy of clinical application.
2020 Vol. 27 (30): 57-60 [Abstract] ( 22 ) HTML (34 KB)  PDF  (0 KB)  ( 14 )
61 Effect of Yiqiyangyin Decoction combined with Mycophenolate Mofetil in the treatment of nephrotic syndrome and its influence on renal function
MA Xiu-ning ;WANG Yuan-yuan; GAO Xiao-jing
Objective To explore the effect of Yiqi Yangyin Decoction combined with Mycophenolate Mofetil (MMF) on renal function in patients with nephrotic syndrome (NS).Methods A total of 60 patients with NS who were treated in our hospital from April 2018 to April 2019 were selected as the observation objects and divided into two groups according to random number table method,30 cases in each group.The control group was treated with Prednison and MMF.The observation group was treated with Yiqi Yangyin Decoction on the basis of the control group,and the renal function indexes before and after treatment and the total effective rate were recorded and compared in detail.The indexes of renal function included urinary protein,blood urea nitrogen (BUN) and serum creatinine (SCr).Results After treatment,the levels of urine protein,BUN and SCr in the observation group were lower than those in the control group,and the total effective rate in the observation group was higher than that in the control group,the differences were statistically significant (P<0.05).Conclusion The combination of Yiqi Yangyin Decoction and MMF can effectively improve the renal function,improve the clinical efficacy,and have a high value of application.It is recommended to vigorously promote.
2020 Vol. 27 (30): 61-63 [Abstract] ( 19 ) HTML (30 KB)  PDF  (0 KB)  ( 10 )
64 Application effect of Salmeterol and Fluticasone Powder Inhalant combined with Methoxyphenamine on acute exacerbation of chronic obstructive pulmonary disease
DU Shu-wei
 Objective To investigate the application effect of Salmeterol and Fluticasone Powder Inhalant combined with Methoxyphenamine on acute exacerbation of chronic obstructive pulmonary disease (COPD).Methods A total of 80 cases with acute exacerbation of COPD admitted to our hospital from February 2018 to February 2020 were selected and divided into two group according to random number table method,40 cases in each group.The control group was given Methoxyphenamine Capsules,the observation group was combined with Salmeterol and Fluticasone Powder Inhalant.Then the changes of ventilator treatment time,total hospitalization time in the two groups were compared.The changes of pulmonary function indexes in the two groups were compared 1 week after treatment.The St.George′s hospital respiratory questionnaire (SGRQ) scores in the two groups were compared.The complications which occurred during the treatment of the two groups were counted.Results The treatment time and total hospitalization time in the observation group were shorter than those in control group (P<0.05),1 week after intervention,the forced expiratory volume in one second (FEV1) and FEV1/forced vital capacity (FVC) levels in the lung function indexes in the observation group were higher than those of the control group (P<0.05),1 week after treatment,the SGRQ score in the observation group was higher than that of the control group (P<0.05),the SGRQ score in the observation group was higher than that before treatment (P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion Salmeterol and Fluticasone Spray for patients with acute exacerbation of COPD can effectively shorten the respiratory support time and hospitalization time of patients,so it can improve lung function and respiratory quality,and it has few complications and high safety.
2020 Vol. 27 (30): 64-66转70 [Abstract] ( 17 ) HTML (36 KB)  PDF  (0 KB)  ( 13 )
67 Analysis of independent risk factors for clinical pregnancy rate of intra-uterine insemination with male factors
LIN Li-na ;ZHANG Zhe-huan; ZHOU Xin-ye ;HUANG Xiao-fan; PAN Ting
Objective To analyze the independent risk factors for clinical pregnancy rate of intra-uterine insemination(IUI) with male factors.Methods Clinical data of 966 cycles of IUI patients who were admitted to Shantou Central Hospital in Guangdong Province from January 2013 to October 2018 were retrospectively analyzed.The relationship between IUI pregnancy rate and factors such as the age of the female,the age of the male,infertility duration,infertility program,type of infertility,number of IUI cycles,total number of forward sperm after treatment was investigated.Results The single-factor analysis results indicated that there were no statistically significant differences in the pregnancy rates among the age of the female,the age of the male,infertility program,type of infertility and the number of IUI cycles (P>0.05).The pregnancy rate of infertility duration ≤3 years was higher than infertility duration >3 years,and the difference was statistically significant (P<0.05).The pregnancy rate of the total number of forward sperm after treatment>107 was higher than the total number of forward sperm after treatment ≤107,and the difference was statistically significant (P<0.05).The multiple-factor analysis results indicated that the infertility duration ≤3 years (β=0.459,OR=1.582,95%CI=1.055-2.372) and the total number of forward sperm after treatment >107 (β=0.671,OR=1.114,95%CI=0.289-1.385) were risk factors of IUI clinical pregnancy rate (P<0.05).Conclusion The infertility duration and the total number of forward sperm after treatment are independent risk factors for the clinical pregnancy rate,while the age of the female,the age of the male,infertility program,the type of infertility and the number of IUI cycles have no significant effect.
2020 Vol. 27 (30): 67-70 [Abstract] ( 22 ) HTML (35 KB)  PDF  (0 KB)  ( 12 )
71 Application value of the concept of accelerated rehabilitation surgery in gynecological laparoscopic surgery patients
LIU Lan-lan; YANG Jing-zhen; LIU Wei
Objective To explore the application value of the concept of accelerated rehabilitation surgery in patients with gynecological laparoscopy.Methods From October 2018 to October 2019,a total of 60 patients undergoing laparoscopic surgery in our hospital were selected as the research objects.According to the random number table method,they were divided into a control group (30 cases) and a test group (30 cases).The control group was given perioperative routine care,the experimental group was given perioperative accelerated rehabilitation surgical care.The postoperative catheter removal time,the time to get out of bed for the first time,the anal exhaust time,the incidence of anesthesiarelated complications and the postoperative visual analogue scale(VAS)score were compared between the two groups.Results The time of urinary catheter removal,the time of getting out of bed for the first time,and the time of anal exhaust in the experimental group were shorter than those in the control group,the differences were statistically significant (P＜0.05).The total incidence of anesthesia-related complications in the experimental group was lower than that in the control group,the difference was statistically significant (P＜0.05).After 24 h,the VAS score of the experimental group was lower than that of the control group,the difference was statistically significant (P＜0.05).Conclusion Under the concept of accelerated rehabilitation surgery,nursing services for patients undergoing gynecological laparoscopic surgery are conducive to shortening postoperative catheter removal time,getting out of bed and anal exhaust time,promoting early postoperative recovery,reducing postoperative complications,and reducing postoperative complications pain,with high nursing value.
2020 Vol. 27 (30): 71-74 [Abstract] ( 21 ) HTML (36 KB)  PDF  (0 KB)  ( 9 )
75 Application value of thrombelastography in detection of blood coagulation function in women with gestational diabetes mellitus
WANG Ying ;ZHENG Xian-fang; GE Xiao-hua

Objective To explore the application value of thrombelastography (TEG) in detection of blood coagulation function in women with gestational diabetes mellitus (GDM).Methods Clinical data of 142 GDM pregnant women who delivered in Chaohu Hospital of Anhui Medical University from October 2017 to October 2019 was were retrospectively analyzed and divided into the GDM group (70 cases) and the control group (72 cases) according to whether the pregnant women had GDM.The routine coagulation function,level of platelet (PLT) and TEG indicators were compared between the two groups.And the correlation analysis was conducted in routine coagulation function indicators and TEG indicators with statistical differences in the GDM group.Results The prothrombin time (PT) in the peripheral blood of the GDM group was longer than that of the control group,the fibrinogen (FIB) was higher than that of the control group,and the differences were statistically significance (P<0.01).The FIB values of the two groups were both higher than the normal range.There were no statistically significant differences in the activated partial thromboplastin time (APTT),thrombin time (TT),D-dimer (DD) and level of PLT between the two groups (P>0.05).The peripheral blood coagulation comprehensive index (CI),maximum amplitude (MA),blood clot mechanical strength (G) and amplitude (A) in the GDM group were higher than those in the control group,and the differences were statistically significant (P<0.05).There were no statistically significant differences in the reaction time (R),coagulation time (K),and clot formation rate (α angle)between the two groups (P>0.05).CI,G and A were positively correlated with PT in GDM group (P<0.05),CI,MA,G and A were positively correlated with FIB in GDM group (P<0.05).Conclusion The blood of women with GDM is prone to form thrombosis,and the thrombus is not easy to fall off.The risk of bleeding in GDM women is also higher than that of normal pregnant women.The TEG indicators are significantly correlated with traditional coagulation indicators.TEG testing for GDM patients is superior to traditional coagulation function detection,which can accurately monitor the patients′ blood status,and provide a basis for clinical anticoagulation and hemostasis.
2020 Vol. 27 (30): 75-78 [Abstract] ( 23 ) HTML (38 KB)  PDF  (0 KB)  ( 9 )
79 Application of Misoprostol in pregnant women with premature rupture of full-term membranes
LI Yang

Objective To investigate the application effect of Misoprostol in premature rupture of fetal membrane at term.Methods From June 2018 to September 2019,a total of 100 cases of premature rupture of membranes to full term pregnant women treated in our hospital were selected as the research objects.According to the random number table,they were divided into observation group and control group,each with 50 cases.The control group accetped Oxytocin,observation group accetped Misoprostol,maternal labor,hormone levels before and after medication,maternal and infant outcomes,adverse drug reactions and other indicators of the two groups were compared.Results The first,second and third stages of labor in the observation group were shorter than those in the control group,and the differences were statistically significant (P＜0.05).The serum progesterone (P) of the two groups of pregnant women 6 h after treatment was lower than that before treatment,while the serum prostaglandin E (PGE) and serum estrogen (E2) levels were higher than those before treatment,and the serum P of the observation group 6 h after treatment was lower than that of the control group,serum PGE,E2 were higher than those of the control group,the differences were statistically significant(P＜0.05).The cesarean section rate in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).There were no statistically significant differences in the rate of postpartum hemorrhage,neonatal asphyxia,and fetal distress between the two groups (P＞0.05).There were no statistically significant differences in the adverse reactions between the two groups of parturients during the medication period(P＞0.05).Conclusion Misoprostol has important application value in the induction of labor with full-term premature rupture of membranes.It can quickly help mothers improve hormone levels,improve maternal and infant outcomes,and has high drug safety.
2020 Vol. 27 (30): 79-81转85 [Abstract] ( 24 ) HTML (35 KB)  PDF  (0 KB)  ( 9 )
82 Application of serum S100B protein in hypoxic-ischemic encephalopathy
HUANG Xiao-ling ;LIN Yue-qing ;ZHOU Bing-xin ;SHEN Fei-min
Objective To explore and analyze the application effect and clinical significance of serum S100B protein in hypoxic-ischemic encephalopathy (HIE) in neonates and provide clinical basis for the assessment of HIE condition and prognosis.Methods A total of 150 HIE children admitted to the neonatology department of our hospital from January to December 2017 were selected as the experimental group.The experimental group was divided into the severe HIE group (40 cases),the moderate HIE group (50 cases) and the mild HIE group (60 cases) according to the severity of the condition.A total of 60 normal neonates were selected as the control group.Serum samples of different groups were collected on the 1st,3rd and 7th days after birth,and serum samples of the control group were collected on the 1st day after birth.Serum S100B protein concentration was measured by enzyme-linked immunosorbent assay (ELISA),and the difference of serum S100B protein concentration between the experimental group and the control group was compared.According to the assessment results of Gesell development scale,all the HIE children were divided into the group with sequelae (41 cases) and the group without sequelae (109 cases),and the serum S100B protein concentrations of the two groups on 1st,3rd and 7th days were compared respectively.Results The serum S100B protein concentration of experimental group on the 1st day after birth was higher than that of the control group,and the difference was statistically significant (P<0.05).The serum S100B protein concentration of experimental group on the 3rd and 7th days after birth were higher than those on the 1st day,and the differences were statistically significant (P<0.05).The serum S100B protein concentration of severe HIE group on the 1st,3rd and 7th days after birth were higher than those of the moderate HIE group and the mild HIE group,and the differences were statistically significant (P<0.05).The serum S100B protein concentration of moderate HIE group on the 1st,3rd and 7th days after birth were higher than those of the mild HIE group,and the differences were statistically significant (P<0.05).The serum S100B protein concentration of group with sequelae on the 1st,3rd and 7th days after birth were higher than those of the group without sequelae,and the differences were statistically significance (P<0.01).Conclusion Serum S100B protein concentration in HIE children is higher than that in normal neonates,and the serum S100B protein concentration of children with sequelae is higher than that of children without sequelae.Therefore,detection of serum S100B protein concentration is conducive to the early diagnosis and prognosis evaluation of neonatal HIE disease.
2020 Vol. 27 (30): 82-85 [Abstract] ( 27 ) HTML (38 KB)  PDF  (0 KB)  ( 10 )
86 Analysis of the status and risk factors of nutritional iron deficiency anemia in infants and young children in children′s physical examination clinic
MENG Hai-xia
Objective To analysis the status and risk factors of nutritional iron deficiency anemia in infants and young children in children′s physical examination clinics.Methods The general information of 200 infants and young children admitted to our children′s physical examination clinic from January 2018 to October 2019 were retrospectively analysised.All the infants and young children were examined for nutritional iron deficiency anemia.The incidence of nutritional iron-deficiency anemia in infants with different feeding methods,different ages and genders were analyzed,and the risk factors for the occurrence of nutritional iron-deficiency anemia in infants and young children were analyzed.Results The incidence of nutritional iron deficiency anemia in breastfed infants was higher than that of mixed-fed infants,and the difference was statistically significant (P＜0.05);the incidence of nutritional iron deficiency anemia in infants from 6 to 12 months was higher than that of infants and young children aged ＞1 to 2,the difference was statistically significant (P＜0.05);the incidence of nutritional iron-deficiency anemia in infants of different genders was compared,the difference was not statistically significant (P＞0.05);the incidence of nutritional iron-deficiency anemia in infants receiving parenting guidance was higher than that of infants receiving parenting guidance,and the difference was statistically significant(P＜0.05);there was no statistically significant difference in the incidence of nutritional iron-deficiency anemia in infants and young children between cities and towns(P＞0.05);there was no statistically significant difference in the incidence of nutritional iron-deficiency anemia in infants and young children who were supplemented with complementary foods from 4 to 6 months and from 7 to 9 months (P＞0.05);the incidence of nutritional iron-deficiency anemia in infants with anemia during pregnancy was higher than that of infants without anemia during pregnancy,and the difference was statistically significant (P＜0.05).The results of multivariate regression analysis showed that breastfeeding (β=2.513,OR=1.021,95%CI=0.864-1.211),6 to 12 months of age (β=2.113,OR=1.792,95%CI=0.980-2.126),no childcare guidance (β=2.452,OR=1.255,95%CI=1.031-1.722),maternal anemia during pregnancy (β=2.108,OR=2.346,95%CI=1.933-3.316) were high risk factors for infant nutritional iron deficiency anemia (P＜0.05).Conclusion The mixed feeding of infants and young children can reduce the risk of nutritional iron deficiency anemia,and the incidence of nutritional iron deficiency anemia decreases with the age of infants and young children.At the same time,the mother′s nutritional status should be appropriately adjusted during pregnancy.Intervention and parenting guidance should be given to reduce the risk of nutritional iron deficiency anemia in infants and young children.
2020 Vol. 27 (30): 86-88转92 [Abstract] ( 21 ) HTML (32 KB)  PDF  (0 KB)  ( 11 )
89 Results of bacterial culture of lactation mastitis patients in milk and pus and its effect on breastfeeding
SHI Li-bo ;YU De-hai ;BU Yu-hui ;GAO Gui-yan ;TIAN Hong-yu
 Objective To observe the bacterial culture results of lactation mastitis patients′ milk and pus,and analyze its influence on breastfeeding.Methods A total of 46 patients with lactation mastitis treated in our hospital from June to July in 2020 were retrospectively analyzed.According to the condition of the disease,they were divided into an early inflammation group (n=26) and an abscess phase group (n=20).Patients of both groups did not return milk and continued to breastfeed.The patients bacterial culture results of milk and pus were observeed,and the impact of continued breastfeeding on patients and infants was analyzed.Results The positive rate of milk bacteria culture in the early inflammation group was 30.8%(8/26);the positive rate of milk bacteria culture in the abscess group was 30.0%(6/20),and the positive rate of pus bacteria culture was 45.0%(9/20);there was no statistically significant difference in the positive rate of milk bacteria culture between the two groups (P＞0.05).Both groups could tolerate breast pain,and there was no statistically significant difference in pain degree evaluation (P＞0.05).All cases were followed up to 1 week after the cure,and there were no adverse reactions such as fever and severe diarrhea in infants.There was no significant difference in the incidence of adverse reactions of infants between the two groups (P＞0.05).Conclusion The detection rate of pathogenic bacteria in the milk of lactation mastitis patients is low,and the rate of infection of infants is extremely low.Continued breastfeeding has no obvious adverse effects on patients and infants.The treatment concept of lactation mastitis that does not return to breastfeeding and does not stop breastfeeding is worthy of clinical promotion.
2020 Vol. 27 (30): 89-92 [Abstract] ( 29 ) HTML (36 KB)  PDF  (0 KB)  ( 10 )
93 Timing of laparoscopic cholecystectomy for treating acute cholecystitis
LIU Jian-jin ;SONG Jun-yong; SUN Fang-qun; CHEN San-lin
Objective To explore the timing of laparoscopic cholecystectomy for treating acute cholecystitis.Methods According to the random number table method,the 60 patients with acute cholecystitis admitted to our hospital from February 2016 to May 2018 were divided into two groups,30 cases in each group.Patients in group A were operated within 72 h of onset,and patients in group B were operated after 72 h of onset.The operation indicators after the operation,treatment costs and complications were compared between the two groups.Results The clinical efficacy of the two groups of patients was not statistically significant (P＞0.05).The operation time,anal exhaust time,postoperative pain time,and hospital stay in group A were shorter than those in group B,and the amount of intraoperative blood loss and postoperative drainage were less than those in group B,the incidence of complications was lower than that in group B,the differences were statistically significant(P＜0.05).Conclusion Laparoscopic cholecystectomy for treatment of patients with acute cholecystitis within 72 h of onset has a good clinical effect,which can effectively relieve the clinical symptoms of patients,reduce trauma,and reduce postoperative infections.
2020 Vol. 27 (30): 93-95 [Abstract] ( 15 ) HTML (31 KB)  PDF  (0 KB)  ( 11 )
96 Effect of totally extraperitoneal prosthesis and transperitoneal hernioplasty on spermatic vessels and testicular function in male patients with inguinal hernia
WANG You-hua ;ZHOU Xue-lu ;ZHANG Huan-bin
Objective To investigate the effect of laparoscopic totally extraperitoneal prosthesis (TEP) and laparoscopic transperitoneal hernioplasty (TAPP) on spermatic cord blood vessels and testicular function in male patients with inguinal hernia.Methods A total of 86 male inguinal hernia patients admitted to our hospital from January 2016 to January 2019 were selected as the research objects.According to the random number table method,they were divided into TEP group (43 cases) and TAPP group (43 cases).The operation and hospitalization,the function of spermatic blood vessels and testis before and after operation,and the complications were compared between the two groups.Results There were no significant differences in the length of operation,intraoperative blood loss and hospital stay between the two groups (P＞0.05);4 weeks after surgery,there were no significant differences in the diameter and velocity of spermatic artery between the two groups (P＞0.05);the diameter of spermatic vein in TAPP group was wider than that in TEP group,and the velocity of blood flow was slower than that in TEP group,and the differences were statistically significant(P＜0.05);4 weeks after surgery， there were no significant differences between the two groups in semen volume,sperm density,sperm survival rate and serum testosterone concentration (P＞0.05);there was no significant difference in the total incidence of complications between the two groups (P＞0.05).Conclusion For male inguinal hernia patients,the efficacy and safety of TEP and TAPP are comparable,and there is no significant effect on spermatic artery and testicular function,but the effect of TEP on spermatic vein is less than that of TAPP.
2020 Vol. 27 (30): 96-98转102 [Abstract] ( 22 ) HTML (35 KB)  PDF  (0 KB)  ( 12 )
99 Effect of oxygen-driven atomization inhalation on the prevention and treatment of radioactive oral mucosal reaction in patients with laryngeal cancer
ZHU Shu-fang; LIU Hua-zhi

Objective To explore the effect of oxygen-driven atomization inhalation on the prevention and treatment of radioactive oral mucosal reaction in patients with laryngeal cancer.Methods A total of 101 patients with laryngeal cancer who underwent radiotherapy in Ganzhou Tumor Hospital from February 2017 to July 2019 were selected.They were divided into the observation group (51 cases) and the control group (50 cases) according to the method of random digital table.Both groups were given routine oral nursing.Meanwhile,the control group received ultrasonic atomization inhalation therapy,and the observation group received oxygen-driven atomization inhalation therapy.The saliva flow,oral pH value at the time of before treatment,radiotherapy dose 33 Gy,the end of radiotherapy and the end of radiotherapy for 1 week and the occurrence of radioactive oral mucosal reaction at the time of radiotherapy dose 33Gy,the end of radiotherapy and the end of radiotherapy for 1 week were compared between the two groups.Results The oral pH value of the observation group at the time of radiotherapy dose 33 Gy,the end of radiotherapy and the end of radiotherapy for 1 week were higher than those of the control group,and the differences were statistically significant (P＜0.05).The saliva flow of the observation group at the time of radiotherapy dose 33 Gy,the end of radiotherapy and the end of radiotherapy for 1 week were greater than those of the control group,and the differences were statistically significant (P＜0.05).The radioactive oral mucosal reaction of the observation group at the time of radiotherapy dose 33 Gy,the end of radiotherapy and the end of radiotherapy for 1 week were better than those of the control group,the differences were statistically significant (P＜0.05).Conclusion Oxygen-driven atomization inhalation can effectively prevent radioactive oral mucosal reaction in patients with laryngeal cancer.
2020 Vol. 27 (30): 99-102 [Abstract] ( 16 ) HTML (36 KB)  PDF  (0 KB)  ( 15 )
103 Clinical effect of complete thoracoscopic surgery in the treatment of early lung cancer
ZHANG Lei
 Objective To study the value of complete thoracoscopic surgery in the treatment of patients with early lung cancer.Methods From January 2017 to January 2020,100 patients with early lung cancer in our hospital were selected and divided into the control group (n=50) and the experimental group (n=50) according to random number table method.The control group was treated with open pulmonary lobectomy,and the experimental group was treated with complete thoracoscopic surgery.The total effective rate,the total incidence rate of complication,pain degree and operation index of the two groups were compared.Results The total effective rate in the experimental group was 90.00%,which was higher than that in the control group accounting for 74.00%,and the difference was statistically significant (P＜0.05).The total incidence rate of complications in the experimental group was 12.00%,which was lower than that in the control group accounting for 28.00%,and the difference was statistically significant (P＜0.05).The pain degree of the experimental group was milder than that of the control group (P＜0.05).The amount of bleeding during operation of the experimental group was less than that of the control group,and the discharge time,drainage time,and operation time of the experimental group were all shorter than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion Complete thoracoscopic surgery in the treatment of patients with early lung cancer can reduce the incidence of complications,pain,shorten the length of hospital stay,improve the total effective rate of treatment,the effect is more ideal.
2020 Vol. 27 (30): 103-105转109 [Abstract] ( 13 ) HTML (34 KB)  PDF  (0 KB)  ( 8 )
106 Influence of total thyroidectomy on parathyroid hormone and blood calcium levels in patients with primary hyperthyroidism and thyroid cancer
WANG Xuan-kai;LI Xian-yong; LIN Guan-mao; HONG Hui;LI Zhi-rong;ZHAN Dong-zai
Objective To investigate the influence of total thyroidectomy on parathyroid hormone (PTH) and blood calcium levels in patients with primary hyperthyroidism and thyroid cancer.Methods A total of 60 patients with primary hyperthyroidism combined with thyroid cancer who were admitted to our hospital from February 2018 to December 2019 were selected as the research subjects.All the selected patients were divided into the control group (30 cases)and the observation group (30 cases) according to random number table method.The control group underwent subtotal thyroidectomy,and the observation group was treated with total thyroidectomy.The clinical indexes,thyroid hormone,blood calcium level,serum level and complications were compared between the two groups.Results The operation time,intraoperative bleeding volume,and hospital stays were compared between the two groups,and the differences were not statistically significant (P>0.05).The levels of total triiodothyronine (TT3),total thyroxine (TT4),PTH and blood calcium were compared between the two groups before surgery,and the differences were not statistically significant (P>0.05).The levels of TT3 and TT4 in the two groups after surgery were higher than those before surgery,the levels of PTH and blood calcium after surgery were lower than those before surgery,the levels of TT3 and TT4 in the observation group after surgery were higher than those in the control group,and the levels of PTH and blood calcium in the observation group after surgery were lower than those in the control group,and the differences were statistically significant (P<0.05).The IL-17 levels of the two groups after surgery were lower than those before operation,and the IL-35 levels of the two groups after surgery were higher than those before operation,the level of IL-17 of the observation group after surgery was lower than that of the control group,while the IL-35 level of the observation group after surgery was higher than that of the control group,and the differences were statistically significant (P<0.05).There was no statistical difference in the total incidence of postoperative complications between the two groups (P>0.05).Conclusion Total thyroidectomy in the treatment of patients with primary hyperthyroidism and thyroid cancer decreases the levels of PTH and blood calcium,but it can regulate the levels of inflammatory factors,which has certain safety.
2020 Vol. 27 (30): 106-109 [Abstract] ( 12 ) HTML (41 KB)  PDF  (0 KB)  ( 6 )
110 Application effect of the different operation methods in early breast cancer patients
LI Liu-ying ;KE Hua; LIU Bao ;LAI Qing; LI Xiao-hong
Objective To explore the application effect of different operation methods in the early breast cancer patients.Methods From January 2018 to March 2019,52 patients with early stage breast cancer (stage Ⅰand stage ⅡA)were selected and divided into the breast-conserving group (28 cases) and the modified radical operation group (24 cases) according to the different treatment methods.The breast-conserving group was treated with the breast-conserving operation,and the modified radical operation group was treated with modified radical operation.The operation time,incision length,intraoperative bleeding volume,hospitalization time and complications were compared between the two groups.Three months after operation,objective excellent rate and subjective total satisfaction of the affected breast were evaluated.Results The operation time,incision length and hospitalization time of the breast-conserving group were shorter than those of the modified radical operation group,and the amount of intraoperative bleeding of the breast-conserving group was less than that of the modified radical operation group,the differences were statistically significant (P<0.05).The total complication rate of the breast-conserving group was 7.14%,which was lower than 20.83% of the modified radical operation group,and the difference was statistically significant (P<0.05).The objective excellent rate and subjective total satisfaction of the breast-conserving group were higher than those of the modified radical operation group,with statistically significant differences (P＜0.05).Conclusion The breast-conserving surgery has less trauma and less complications in the treatment of early breast cancer,and can obtain better breast appearance effect and higher satisfaction.
2020 Vol. 27 (30): 110-112转116 [Abstract] ( 15 ) HTML (33 KB)  PDF  (0 KB)  ( 13 )
113 Effect of simultaneous transurethral resection of bladder tumor and transurethral resection of prostate in the treatment of superficial bladder cancer complicated with benign prostatic hyperplasia
TANG Yun-feng
Objective To investigate the effect of simultaneous transurethral resection of bladder tumor (TURBT) and transurethral resection of prostate (TURP) in the treatment of superficial bladder cancer with benign prostatic hyperplasia.Methods A total of 36 patients with superficial bladder cancer combined with benign prostatic hyperplasia admitted to our hospital from January 2019 to January 2020 were selected as study subjects,and they were divided into the control group (18 cases) and the observation group (18 cases) according to the random number table method.TURBT treatment was applied to the control group,while TURBT and TURP treatment were applied to the observation group.Surgical indexes,changes in residual urine volume,clinical efficacy and total incidence of complications were compared between the two groups.Results The operative time of the observation group was longer than that of the control group,the intraoperative blood loss of the observation group was more than that of the control group,and the duration of indwelling catheter of the observation group was shorter than that of the control group (P＜0.05).After surgery,the residual urine volume of the two groups was less than that before operation,and the residual urine volume in the observation group after treatment was less than that in the control group (P＜0.05).The total effective rate of the observation group was 94.44%,which was higher than 66.67% in the control group (P＜0.05).The total incidence rate of complication of the observation group was 5.56%,which was lower than 33.33% of the control group (P＜0.05).Conclusion After the treatment of TURBT and TURP at the same time,the amount of residual urine and the incidence of complications can be significantly reduced in the patients of superfical bladder cancer complicated with benigh prostatic hyperplasia.
2020 Vol. 27 (30): 113-116 [Abstract] ( 13 ) HTML (34 KB)  PDF  (0 KB)  ( 11 )
117 Effect comparison of local injection of Ankylosaurus in different parts for treating low frequency descending sudden sensorineural hearing loss in patients with type 2 diabetes
LIU Dan; WAN Lang; PENG Cong; WANG Tao-jiao
Objective To compare the effect,complication and influgnce on blood glucose of tymamtic injection and retroaurel injection of Ankylosaurus in the treatment of low frequancy desconding suddon sensorineural hearing loss with type 2 diabetes..Methods From January 2016 to June 2018,72 patients with low-frequency descending sudden deafness accompanied by type 2 diabetes were selected and randomly divided into tympanic injection group and retroaural injection group with 36 cases each according to simple randomization.Both groups received conventional treatment.On this basis,the tympanic injection group and the posterior auricular injection group received methylprednisolone injections into the tympanic cavity and behind the ear,respectively.The clinical efficacy and adverse reactions of patients of the two groups were compared.Results The total effective rate of the post-auricular injection group was 80.56%,and the total effective rate of the tympanic injection group was 66.67%.The total effective rate of the post-auricular injection group was higher than that of the tympanic injection group,the difference was statistically significant(P＜0.05).After 14 days of treatment,the hearing thresholds of the two groups were lower than those before treatment,the differences were statistically significant (P＜0.05);the hearing improvement value of the behind the ear injection group was higher than that of the tympanic cavity injection group,the difference was statistically significant (P＜0.05).There was no risk of tympanic membrane perforation in the post-auricular injection group,the incidence of local pain and transient vertigo in the behind the ear injection group were 22.22% and 5.56%,respectively;the tympanic injection group was 63.89% and 27.78%,the rate of local pain and the incidence of transient vertigo in the tympanic cavity injection group were higher than those in the behind the ear injection group,the differences were statistically significant(P＜0.05).Conclusion Behind-auricular injection of methylprednisolone has good curative effect in the treatment of low-frequency descending sudden deafness with type 2 diabetes,and it is simple and practical.It can be popularized and applied in clinic.
2020 Vol. 27 (30): 117-120 [Abstract] ( 18 ) HTML (38 KB)  PDF  (0 KB)  ( 10 )
121 Effect comparison of internal limiting membrane packing and flip coverage treating refractory macular hole
LIU Wei-dong ;ZHAN Tian-yin; BAI He-nan
Objective To analyze the effect of internal limiting membrane packing and flip coverage treating refractory macular holes.Methods A total of 78 patients with refractory macular hole who were treated in our hospital from January 2018 to December 2019 were selected and divided into a control group and an observation group according to the random number table method,39 patients in each group.The control group was treated with inner limiting membrane packing,and the observation group was treated with flip coverage.The closure of the hole,the treatment time of the inner limiting membrane,and the best-corrected visual acuity (BCVA) level before and after treatment were compared between the two groups.Results The puncture closure rate of the observation group was 92.31%,it was higher than that of the control group which was 74.36%,the internal limiting membrane treatment time was (617.27±60.57)s,it was longer than the control group which was (455.38±43.92)s,the differences were statistically significant(P＜0.05).Before the operation,the BCVA levels of the two groups were compared,and the differences were not statistically significant(P＞0.05);the BCVA levels of the two groups were lower than those before the operation at 1 month and 3 months after the operation,and the difference was statistically significant (P＜0.05);1 month and 3 months after operation,the BCVA levels of the two groups were not statistically different (P>0.05).Conclusion Flip coverage treatment can increase the hole closure rate of patients with refractory macular hole and effectively improve the patient′s BCVA level,which is worthy of clinical application.
2020 Vol. 27 (30): 121-123 [Abstract] ( 16 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
124 A case report of local flaps in repairing full-thickness defect of recurrent nasal alar basal cell carcinoma
YAN Ning;WU Wen-ke; HU Ge; ZHU Zhen-hua
External nasal basal cell carcinoma comes from the basal layer of the epithelium and belongs to the category of skin cancer.It is more common in the elderly and has a lower degree of malignancy.In the early period,it can appear as a dark brown nodule.The typical symptoms can be seen in the central skin rupture,with black scab attached to the surface,which does not heal for a long time.The diagnosis must rely on medical examination.Surgical treatment is often preferred in clinical practice,and close follow-up is required after surgery to prevent tumor recurrence.In order to improve the cognitive sensitivity to malignant tumor recurrence,1 case of full-thickness defect of recurrent nasal alar basal cell carcinoma was reported,and the clinical effect of local flaps repair for full-thickness defect of nasal alar was evaluated.
2020 Vol. 27 (30): 124-126 [Abstract] ( 16 ) HTML (30 KB)  PDF  (0 KB)  ( 11 )
127 Influence of ultrasound combined with nerve stimulator guidance on the effect of axillary brachial plexus block
FU Xiang ;LIU Ke-xuan;XUE Jin-pei ;YU Xue-gang ;YANG Ting
 Objective To compare the influence of ultrasound combined with nerve stimulator guidance and ultrasound guidance on the effect of axillary brachial plexus block.Methods A total of 100 patients who intended to undergo forearm and hand surgery in our hospital from January to April 2018 were selected as the research objects,and the patients were divided into ultrasound combined with nerve stimulator group (group NU) and control group (group U) by the random number table method,50 cases in each group.The group NU was guided by ultrasound combined with nerve stimulator,and the group U was only guided by ultrasound.The anesthesia effect,nerve block onset time,operation and incidence of complications between the two groups were observed.Results The success rate of nerve block anesthesia in the group NU (100.00%) was higher than that in group U (72.00%),the difference was statistically significant (P<0.05).The sensory block onset time of musculocutaneous nerve,radial nerve,median nerve and ulnar nerve in the group NU was shorter than that in the group U,and the difference was statistically significant (P<0.05).The operation time in the group NU was shorter than that in the group U,and the duration of nerve block was longer than that in the group U,with statistically significant differences (P<0.05).The total incidence of complications in the group NU (4.00%) was lower than that in the group U (26.00%),and the difference was statistically significant (P<0.05).Conclusion Ultrasound combined with nerve stimulator to guide axillary brachial plexus block has a higher success rate,shorter onset time,operation time,longer duration,and fewer complications,indicating that ultrasound combined with nerve stimulator to guide axillary brachial plexus block is effective and safe.
2020 Vol. 27 (30): 127-130 [Abstract] ( 17 ) HTML (40 KB)  PDF  (0 KB)  ( 11 )
131 Application of different doses of Ropivacaine Hydrochloride in patients with subarachnoid anaesthesia
LUO Hong
Objective To investigate the application effect of different doses of Ropivacaine Hydrochloride in patients with subarachnoid anaesthesia.Methods The clinical data of 100 patients with subarachnoid anaesthesia in the hospital from July to December 2019 were retrospectively analyzed.They were divided into the control group (50 cases) and the observation group (50 cases) according to different doses of Ropivacaine Hydrochloride.The control group was given middle dose of Ropivacaine Hydrochloride,and the observation group was given low dose of Ropivacaine Hydrochloride.The anesthetic effect,Bruggrmann comfort scale(BCS)score,autonomic urination function,indwelling catheterization and the total incidence of complications were compared between the two groups.Results The plane fixed time of the observation group was longer than that of the control group,and the postoperative recovery time of motion in the observation group was earlier than that in the control group,with statistically significant differences (P<0.05).The BCS scores in the observation group at different time after surgery were higher than those in the control group,with statistically significant differences (P<0.05).The BCS scores in the control group after surgery for 6 h (T2) and after surgery for 24 h (T3) were higher than those in same group after surgery for 3 h (T1),with statistically significant differences (P<0.05).There were no statistically significant differences in the BCS scores in the observation group at different time after surgery (P>0.05).The urination frequency and residual urine volume increased at T3 in the two groups,and the maximum bladder pressure volume decreased.However,the urination frequency and residual urine volume at T3 in the observation group were lower than those in the control group,and the maximum bladder pressure volume was higher than that in the control group,the differences were statistically significant (P<0.05).The indwelling catheterization rate and the total incidence of complications in the observation group were lower than those in the control group,with significant statistically differences (P<0.05).Conclusion Low dose of Ropivacaine Hydrochloride in subarachnoid anaesthesia has better effect,it can increase postoperative comfort,alleviate the degree of autonomic urination function damage,reduce indwelling catheterization rate and reduce the incidence of complications.
2020 Vol. 27 (30): 131-134 [Abstract] ( 14 ) HTML (38 KB)  PDF  (0 KB)  ( 8 )
135 Application of Dezocine in patients undergoing gynecologic laparoscopic surgery before the end of surgery
ZHANG Shan-ni ;LI Jing; XIU Yu-fang
Objective To explore the effect of Dezocine used before the end of surgery on postoperative recovery and pain of patients undergoing gynecological laparoscopic surgery.Methods A total of 80 cases of patients with hysteromyoma undergoing laparoscopic myomectomy from February 2019 to April 2020 were selected and divided into the observation group and the control group according to the random number table method,40 cases in each group.The observation group received Dezocine intravenously at 15 min before the end of the surgery,and the control group only received 1 mg Fentanyl.Then the changes of related indexes during anesthesia recovery were compared.The changes of pain numerical rating scale (NRS) scores at different time points after surgery were compared.The changes of objective indexes of pain (serum substance P [SP] and serum neuropeptide [NPY]) between the two groups during anesthesia recovery were compared.The incidence of complications in the two groups was counted.Results The recovery breathing time,consciousness recovery time and tracheal extubation time in the observation group were shorter than those in the control group,with statistically significant differences (P<0.05).The NRS scores of pain in the observation group were lower than those in the control group at 12,24 and 48 h after surgery,with statistically significant differences (P<0.05).During anesthesia recovery,the SP and NPY levels in the observation group were lower than those in the control group,with statistically significant differences (P<0.05).The total proportion of dizziness,nausea,vomiting,constipation and burst pain in the observation group was lower than that in the control group,with statistically significant difference (P<0.05).Conclusion Dezocine analgesia for gynecologic laparoscopic surgery can effectively promote anesthesia recovery and reduce pain score and the release of pain-causing substances,and it has few adverse reactions and high safety.
2020 Vol. 27 (30): 135-137 [Abstract] ( 12 ) HTML (35 KB)  PDF  (0 KB)  ( 13 )
138 Effect of early drinking water on oropharyngeal comfort and gastrointestinal function recovery of patients after tracheal intubation under general anesthesia
TAO Zhu-chun
Objective To explore the effect of early drinking water on oropharyngeal comfort and gastrointestinal function recovery in patients after tracheal intubation under general anesthesia.Methods Totally 98 patients with tracheal intubation under general anesthesia in our hospital from November 2018 to November 2019 were selected as research subjects,and they were divided into group A and group B by the random number table method,with 49 cases in each group.Group A drank water early and group B banned drinking after surgery.The oropharyngeal comfort,gastrointestinal function,postoperative hypotension,and incidence of adverse reactions were compared between the two groups.Results The oropharyngeal dryness,pharyngeal pain scores and incidence rate of oral odor in group A were lower than those in group B,and the differences were statistically significant (P<0.05).The first exhaustion time,bowel sound recovery time,and first defecation time in group A were shorter than those in group B,and the differences were statistically significant (P<0.05).The incidence of postoperative hypotension in group A was lower than that in group B(4.08% vs.18.37%),and the difference was statistically significant (P<0.05).There was no significant difference in the total incidence of gastrointestinal adverse reactions between group A and group B (16.34% vs.18.36%) (P>0.05).Conclusion Early drinking water after tracheal intubation under general anesthesia can improve oropharyngeal comfort,promote gastrointestinal function recovery,reduce postoperative hypotension,and will not increase adverse reactions.
2020 Vol. 27 (30): 138-140转144 [Abstract] ( 17 ) HTML (34 KB)  PDF  (0 KB)  ( 9 )
141 Research on Chinese and western medicine diagnosis and syndrome facters of gastroe-sophageal reflux disease in Fuzhou university town
WANG Qing-lian;SHAO Yan-feng; WANG Jian-ping;NING Lu-feng;CHEN Wen-hui; YE Ting-ting
Objective To explore the symptoms and characteristics of gastroe-sophageal reflux disease in the university town of Fuzhou, the types of traditional Chinese medicine (TCM) and the characteristics of TCM syndromes, so as to provide references for clinical diagnosis and treatment. Methods A total of 120 gastroe-sophageal reflux disease patients admitted to our hospital from January to December of 2019 were selected as the research objects. The patient′s symptoms, gastroesophageal reflux disease questionnaire (GerdQ) points, TCM syndrome types, and TCM syndrome elements were analyzed and studied. Results The average score of GerdQ was (10.48±1.22) points; acid reflux, heartburn, epigastric pain, abdominal distension, belching, and retrosternal pain were the main symptoms, and restless night sleep, nausea, constipation, throat discomfort, dry mouth, bitter mouth, etc. were the main accompanying symptoms; stagnation of heat in the liver and stomach, damp-heat of spleen deficiency, and deficiency of Qi and Ni were the main TCM syndrome types; liver, spleen, stomach and gallbladder were the main diseases of this disease; dampness, heat, qi stagnation, food accumulation, qi deficiency and phlegm were the main diseases. Conclusion The patients with GRED in Fuzhou university town are mainly mild and have complicated clinical manifestations. TCM syndrome differentiation and treatment should take liver, spleen, stomach and gallbladder as the disease location, and pay attention to the pathological characteristics of multiple dampness and heat, stagnation of qi, deficiency of qi, and food accumulation.
2020 Vol. 27 (30): 141-144 [Abstract] ( 15 ) HTML (1 KB)  PDF  (0 KB)  ( 8 )
145 Correlation analysis of traditional Chinese medicine constitution,five evolutive phases and six climatic factors with recurrent respiratory tract infection children
CAI Ying
Objective To explore the correlation between children′s recurrent respiratory tract infection and the constitution of traditional Chinese medicine,five evolutive phases and six climatic factors.Methods From January 2016 to December 2017,a total of 200 children with recurrent respiratory tract infection admitted to Beihai Hospital of Chinese Medicine were selected as the treatment group,and a total of 200 healthy children who had physical examination in our hospital at the same time were selected as the control group.The birth time of all the cases were converted into the year of trunk and branch,and on this basis,they were summarized and sorted out according to the corresponding period of "five movements" and "six factors in nature".The correlation between the two groups′ constitution of traditional Chinese medicine,five movements and six factors in nature was compared and made clear.Results The proportions of phlegm-dampness and qi-deficiency,Jinyun and Huoyun,Yangming Zaojin and Jueyin Fengmu in the treatment group were higher than those in the control group,the differences were statistically significant (P＜0.05).There was no statistically significant difference in the diet of the groups (P＞0.05).The results of multivariate Logistic regression analysis indicated that Jueyin Fengmu (β=0.035,OR=1.054,95%CI=0.965-1.147),Jinyun (β=0.023,OR=1.120,95%CI=0.783-1.235),phlegm dampness constitution (β=0.995,OR=4.634,95%CI=3.413-5.263),Qi deficiency constitution (β=0.019,OR=1.197,95%CI=0.567-2.998) were the risk factors of recurrent respiratory infection in children (P＜0.05).Conclusion The incidence of children with recurrent respiratory tract infection is correlative with the factors including Jueyin Fengmu,Jinyun,phlegm dampness and qi deficiency constitution.
2020 Vol. 27 (30): 145-147转151 [Abstract] ( 12 ) HTML (35 KB)  PDF  (0 KB)  ( 8 )
148 Effect of quick acupuncture therapy on immediate blood pressure in patients with irascibility hyperactivity essential hypertension
LYU Hai-bo; SONG Jin-xing
Objective To observe the effect of quick acupuncture therapy on immediate blood pressure in patients with irascibility hyperactivity essential hypertension.Methods A total of 140 patients with irascibility hyperactivity essential hypertension admitted to Department of Community of Zhongguancun Hospital from February 2019 to February 2020 were selected as the research objects and divided into the treatment group and the control group by the random number table method,with 70 patients in each group.Patients in the treatment group were given quick acupuncture and patients in the control group were given retaining acupuncture.Blood pressures,traditional Chinese medicine (TCM)symptom scores before and after treatment,the therapeutic effect and the occurrence of adverse reactions were compared.Results The systolic blood pressures,diastolic blood pressures and TCM symptom scores of the two groups after treatment were lower than those before treatment,and the differences were statistically significant (P<0.01).There were no statistically significant differences in the systolic blood pressures,diastolic blood pressures and TCM symptom scores of the two groups after treatment (P>0.05).There was no statistically significant difference in the total effective rate between the treatment group (75.71%) and the control group (74.29%) (P>0.05).Conclusion Quick and retaining acupuncture on patients with irascibility hyperactivity essential hypertension have a significant immediate effect of lowering blood pressure and effect of improving the TCM symptoms of hypertension.Both of them have similar efficacy,but quick acupuncture has the advantage of convenient and fast operation,which can be popularized as an immediate antihypertensive method in clinical practice.
2020 Vol. 27 (30): 148-151 [Abstract] ( 13 ) HTML (36 KB)  PDF  (0 KB)  ( 9 )
152 Clinical effect of spleen-strengthening massage in traditional Chinese medicine for children in the treatment of infant cow′s milk protein allergy
LI Jing-peng; WANG Meng-meng; GAO Ping ;WEI Hong ;WANG Gen-xiang
Objective To observe the clinical effect of spleen-strengthening massage in traditional Chinese medicine for children in the treatment of infant cow′s milk protein allergy (CMPA).Methods A total of 80 children with CMPA admitted to our hospital from January 2018 to January 2020 were divided into the control group and the observation group by random number table method,with 40 cases in each group.The control group was treated with diet avoidance and alternative therapy,and the observation group was treated with spleen-strengthening massage based on diet avoidance and alternative therapy.After 3 months treatment,the clinical efficacy,weight and height growth of the two groups were compared.Results The total effective rate of the observation group (95.0%) was higher than that of the control group (80.0%),and the difference was statistically significant (P<0.05).The weight growth of the observation group([1.07±0.27] kg) was higher than that of the control group ([2.65±0.67] kg),and the difference was statistically significant (P<0.05).The height growth of the observation group ([3.06±0.91] cm) was higher than that of the control group([2.65±0.67] cm),and the difference was statistically significant (P<0.05).Conclusion On the basis of diet avoidance and alternative therapy,spleen-strengthening massage in traditional Chinese medicine for children with CMPA can significantly improve the clinical therapeutic effect and promote the growth and development of children.
2020 Vol. 27 (30): 152-154 [Abstract] ( 18 ) HTML (33 KB)  PDF  (0 KB)  ( 12 )
155 Clinical diagnosis significance of combined detection of serum β-HCG and progesterone in early threatened abortion
SHEN Shuang-yu
Objective To explore the clinical diagnosis significance of combined detection of serum β-human chorionic gonadotrophin (β-HCG) and progesterone in early threatened abortion.Methods A total of 120 pregnant women with threatened abortion in our hospital from December 2017 to December 2019 were selected as the observation group,and they were further divided into the continuing pregnancy group (68 cases) and the pregnancy failure group (52 cases) according to clinical outcome.A total of 120 normal pregnant women in the same period were selected as the control group.Serum β-HCG and progesterone levels in all pregnant women were detected and the diagnostic efficacy of serum β-HCG and progesterone in early threatened abortion were analyzed.Results The serum β-HCG and progesterone levels of the pregnant women in the continuing pregnancy group and the pregnancy failure group were lower than those in the control group(both P＜0.01).The levels of β-HCG and progesterone in the continued pregnancy group were higher than those in the pregnancy failure group (both P＜0.01).Spearman correlation analysis showed that the serum β-HCG and progesterone levels were negatively correlated with early threatened abortion (rs β-HCG=-0.846,rs progesterone=-0.694).The area under the ROC curve corresponding to β-HCG was 0.896,the area under the ROC curve corresponding to progesterone was 0.748,and the area under the ROC curve corresponding to β-HCG + progesterone diagnosis was 0.948.Conclusion Serum β-HCG and progesterone levels change significantly in pregnant women with threatened abortion.The combined detection of serum β-HCG and progesterone is of great value in the diagnosis of early threatened abortion.
2020 Vol. 27 (30): 155-157转161 [Abstract] ( 12 ) HTML (34 KB)  PDF  (0 KB)  ( 11 )
158 Clinical distribution and drug resistance analysis of Ureaplasma urealyticum and Mycoplasma hominis infection in Yangjiang People′s Hospital in 2019
HE Guo-hua; CHEN Dong-ling; LI Qing-mei ;CHEN Jin-ling; LI Shuai ;YANG Li-ping
Objective To analyze the clinical distribution and drug resistance characteristics of Mycoplasma detected in our hospital in 2019 to provide basis for the rational use of antibiotics.Methods The gender ratio,age distribution,department distribution and drug resistance of Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) detected in our hospital in 2019 were analyzed retrospectively.Results A total of 1300 cases (169 males and 1131 females) of Uu and 161 cases (6 males and 155 females) of Mh were detected in 2019.Mycoplasma was distributed in all age groups,Uu was mostly detected in ≤25 years old patient group.In terms of department distribution,the departments were mainly concentrated in gynecology(Uu:64.77%,Mh: 75.16%),obstetrics (Uu: 9.23%,Mh: 10.56%),urology (Uu: 10.54%,Mh: 3.73%),reproductive medicine (Uu: 8.31%,Mh: 3.73%),other departments accounted for less.Drug sensitivity results showed that Uu had a strong sensitivity to Doxycycline,Fulminomycin,Acrosamycin,Clarithromycin,Azithromycin,with the sensitivity rates of 92.69%,93.00%,97.69%,88.69%,77.23%,respectively,while Mh was more sensitive to Doxycycline,Fulminomycin,Acrosamycin,with the sensitivity rates of 86.33%,86.96%,91.3%.Conclusion The Mycoplasma infection detected in our hospital is mainly Uu,the antibiotics should be used according to the results of clinical drug sensitivity in clinical departments.
2020 Vol. 27 (30): 158-161 [Abstract] ( 13 ) HTML (33 KB)  PDF  (0 KB)  ( 8 )
162
Value of combined detection of Hcy,Cys-C and ACR in the early stage diagnosis of diabetic nephropathy
 
Value of combined detection of Hcy,Cys-C and ACR in the early stage diagnosis of diabetic nephropathy
 
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Objective To explore the value of combined detection of Hcy,Cys-C and ACR in the early stage diagnosis of diabetic nephropathy (DN).Methods A total of 125 cases of DN patients treated in our hospital from February 2019 to January 2020 were selected as the observation group,125 cases of simple diabetes patients in the same period were selected as the control group,and 125 cases of healthy people in the same period were selected as the healthy group.The levels of ACR,Hcy and Cys-C were compared among the three groups,and their clinical value in the early diagnosis of DN was discussed.Results The levels of Hcy,Cys-C and ACR in the observation group were higher than those in the control group and the healthy group (P＜0.05).The levels of Hcy,Cys-C and ACR in the control group were higher than those in the healthy group (P＜0.05).The positive rates of combined detection of Hcy,Cys-C and ACR in the observation group and the control group were higher than those of single indicator (P＜0.05).Area under the curve of combined detection of Hcy,Cys-C and ACR was higher than that of single indicator (P＜0.05).Conclusion The combined detection of Hcy,Cys-C and ACR is of great significance,which is helpful for improving the accuracy of the early diagnosis of DN,it is worthy of being promoted.
2020 Vol. 27 (30): 162-164 [Abstract] ( 14 ) HTML (32 KB)  PDF  (0 KB)  ( 12 )
165 Detection and clinical significance of antibody spectrum of autoimmune liver disease related autoimmune liver disease
SHI Jian-xiong
Objective To investigate the detection and clinical significance of antibody spectrum of autoimmune liver disease related to autoimmune liver disease.Methods From March 2018 to January 2020,30 patients with autoimmune hepatitis (AIH),30 patients with primary biliary cirrhosis (PBC),30 patients with primary sclerosing cholangiopathy(PSC) and 30 healthy subjects who voluntarily participated in this project in our hospital were selected.The serum anti nuclear antibody (ANA),anti mitochondrial antibody (AMA) and anti smooth muscle antibody (SMA) antibodies of the four groups of subjects were measured by indirect immunofluorescence.The levels of anti soluble liver antigen/ liver hepatopancreas antigen(SLA/LP)and liver kidney microsomal antibody type Ⅰ(LKM-Ⅰ)were determined by immunoblotting and the results were compared.Results The positive rates of serum ANA in the AIH group,the PBC group,and the PSC group were higher than those of the healthy group (P＜0.05).The positive rate of serum ANA in the AIH group was higher than that of the PBC group and the PSC group (P＜0.05).The positive rate of serum AMA in the PBC group was higher than that in the AIH group,the PSC group and the healthy group (P＜0.05).The positive rates of SMA titer ≥1/320,SLA/LP,and LKM-Ⅰin the AIH group were higher than those in the PBC group,the PSC group and the healthy group (P＜0.05).Conclusion The antibody spectrum of autoimmune liver disease is feasible for clinical diagnosis of autoimmune liver disease and has important guiding value.
2020 Vol. 27 (30): 165-167 [Abstract] ( 18 ) HTML (31 KB)  PDF  (0 KB)  ( 11 )
168 Analysis of the current situation and causes of language retardation in children aged 0-3 in Yaoshan community
YUAN Yun
 Objective To investigate the incidence of language retardation in children aged 0-3 in Yaoshan community of Ji′nan City,analyze the cause of the disease,so as to provide scientific basis for clinical early detection,early intervention and early treatment of children′s language retardation.Methods Denver developmental screen test (DDST)screening tool was used to screen 2707 children suspected with language retardation aged 0-3 years old who came to our children′s care clinic for physical examination from September 2016 to December 2019.Then the suspicious children were diagnosed with Gesell sheet.All parents of children should fill in the questionnaire (informed consent of parents of children).Results The incidence rate of language retardation in children aged 0-3 years was the highest at >1 to 2 years.The incidence was related to gender,and the incidence was higher in boys than girls,and the difference was statistically significant (χ2=21.27,P<0.05).There were statistically significant differences in the incidence rates of language retardation under different circumstances of hypoxic asphyxia at birth,ischemic hypoxic encephalopathy at birth,mothers′ intrauterine distress during pregnancy,pathological jaundice in the newborn period,mothers′ education level,the parenting style of the main caregiver,the time to communicate with the children,time to watch TV,play mobile phones or electronic products every day (P<0.05).There was no significant difference in incidence rate of language retardation under different fathers′ educational level (P>0.05).Hypoxic asphyxia at birth,ischemic hypoxic encephalopathy at birth or mothers′ intrauterine distress during pregnancy,pathological jaundice in the newborn period,low education level of mothers,children′s education style (doting and scolding),less communication with children,and long contact time of electronic screen were the risk factors of children′s language retardation (P<0.05).Conclusion The causes of language retardation in children aged 0-3 are closely related to hypoxia asphyxia at birth,hypoxic ischemic encephalopathy at birth,pathological jaundice,mothers′ intrauterine distress during pregnancy,low education level of mothers,children′s education style (doting and scolding),less communication with children,and long contact time of electronic screen.
2020 Vol. 27 (30): 168-171转176 [Abstract] ( 17 ) HTML (37 KB)  PDF  (0 KB)  ( 12 )
172 Analysis of influencing factors of psychological education satisfaction in clinical medical students and improvement countermeasures
LI Dian-dian; LIU Yi; WANG Bo

Objective To explore the influencing factors of psychological education satisfaction in clinical medical students,and to provide advices for teaching reform.Methods A survey was conducted in October 2019 on 250 students who had learned medical psychology in West China School of Medicine,Sichuan University.The contents included the current situation of the students and their courses of medical psychology,the satisfaction of the course and its influencing factors,understanding and the expectation to the course.Results The survey recovered 247 questionnaires.Theory teaching was still the main teaching mode.Teaching materials were less related to clinical practice,and closedbook examination was the main exam form.The main parts expected to reform were to increase internship opportunities,case analyses,and to improve the quality of teaching.The average score of satisfaction was (3.78±0.85) points.Dissatisfaction with teaching level,closed-book examination in the form of assessment,teaching materials that did not integrate clinical practice,and no practical learning were important factors influencing the overall satisfaction (P<0.05).Conclusion Satisfaction of psychology for medical students is generally high.Optimizing the curriculum,integrating the faculty,enriching the teaching and assessment methods,and adjusting the teaching materials may have positive effect on improvement of the quality of psychological education in clinical medical students.
2020 Vol. 27 (30): 172-176 [Abstract] ( 14 ) HTML (42 KB)  PDF  (0 KB)  ( 12 )
177 Analysis on the refined management of hospital logistics cost
ZHAO Yong
 With the reform of medical model in China,people′s requirements for medical technology,service quality and diagnosis and treatment environment are also increasing year by year,which brings greater challenges to the development of medical career.However,due to the lack of perfect management ability in some hospitals,the logistics cost has increased significantly.With the innovation of hospital logistics cost management mode,the traditional extensive management mode has also changed to the standardized and refined mode gradually,which saves a lot of human,material and financial resources for the hospital.The use of refined management in hospital logistics management is in line with the needs of the current era.It is an effective measure to solve the contradiction between people′s growing medical and health needs and outdated management methods.Only by introducing the concept of refined management into the logistics management of hospital,can the current backward management methods be changed,to realize the unity of management and service,and reduce the hospital Logistics management cost.This paper analyzes the problems in the refined management of hospital logistics cost in detail,and analyzes the measures to solve the problems in combination with the actual situation of the current hospital logistics management,so as to provide reference for the application of refined management in the hospital logistics cost management.
2020 Vol. 27 (30): 177-179 [Abstract] ( 14 ) HTML (31 KB)  PDF  (0 KB)  ( 11 )
180 Application effect of PDCA management in the nursing management of children with bronchopneumonia
SU Li-duan; HUANG Feng-ling; WANG Li-ming
Objective To explore the application effect of PDCA management in the nursing management of children with bronchial pneumonia.Methods A total of 90 children with bronchial pneumonia in our hospital from January 2018 to June 2019 were selected and divided into the control group and the study group by the random number table method,with 45 cases in each group.The control group received routine care,and the study group received PDCA management on the condition of the control group.The nursing management effect,lung function,disappearance time of symptoms,hospitalization time and total satisfaction degree were compared between the two groups.Results The nursing management effect of the study group was higher than that of the control group,the difference was statistically significant (P<0.05).The lung function of the study group was higher than that of the control group,the difference was statistically significant (P<0.05).The disappearance time of symptoms in the study group was earlier than that in the control group,the difference was statistically significant (P<0.05).The hospitalization time in the study group was shorter than that in the control group,the difference was statistically significant (P<0.05).The total satisfaction degree in the study group was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion In the nursing management of children with bronchial pneumonia,PDCA management is effective and worthy of clinical use.
2020 Vol. 27 (30): 180-182 [Abstract] ( 15 ) HTML (34 KB)  PDF  (0 KB)  ( 9 )
183 Implementation and thinking of the rehabilitation training IRT teaching method in the experimental online teaching of medical imaging during the COVID-19 outbreak
LIU He; XING Jian; LIANG Hai-yu ;ZHANG Xin-miao ;WEI Xiu-fang ;ZHU Min ;ZOU Ting ;LIANG Shuang
Objective To discuss the application of online teaching of image recovery training (IRT) in the teaching of medical imaging experiments,based on the background of COVID-19,to implement the instruction spirit of "classsuspended but still learning",to reform and explore the teaching of medical imaging experimental courses.Methods A total of 300 medical imaging diagnostic students of 2016 from Mudanjiang Medical University were selected.According to random lottery method,they were randomly divided into 2 groups: 150 in the experimental group and 150 in the control group.The rehabilitation training IRT teaching method was used in the experimental group,while the traditional experimental teaching method was used in the control group.Through the evaluation results of students′ various achievements and questionnaire evaluation,a conclusion could be drawn.Results The basic theoretical score of the experimental group was (92.27±5.75) points,which was higher than that of the control group of (90.40±5.20) points,the difference was statistically significant (P<0.05).The case analysis score of the experimental group was (92.26±5.75)points,which was higher than that of the control group of (89.91±5.89) points,the difference was statistically significant(P<0.05).The practical ability and ideological and political performance of the experimental group was (92.31±5.65)points,which was higher than that of the control group of (90.35±5.37) points,the difference was statistically significant(P<0.05).The retest score of the experimental group after class was (93.56±4.72) points,which was higher than that of the control group of (91.66±5.72) points,the difference was statistically significant (P<0.05).Conclusion Providing an innovative teaching model for the clinical teaching reform of medical imaging,it not only solves the difficult problem of experimental teaching during the epidemic,but also triggers thinking about the development of experimental teaching,and provides practical experience for online-offline mixed teaching in the future.After returning to school,the reform of traditional teaching will be realized.
2020 Vol. 27 (30): 183-186 [Abstract] ( 13 ) HTML (36 KB)  PDF  (0 KB)  ( 11 )
187 Effect of motivational interviewing on illness perception and self-perceived burden in acute myocardial infarction patients with PCI
WANG Yan-ping; LI Li-jun; BI Li-jun ;HUANG Li-juan
Objective To investigate the effect of motivational interviewing on illness perception and self-perceived burden in acute myocardial infarction (AMI) patients with percutaneous coronary intervention (PCI).Methods A total of 80 AMI patients with PCI who were admitted to our hospital from January 2019 to February 2020 were divided into the control group and the experimental group according to random number table method,with 40 cases in each group.The control group was given routine nursing,and the experimental group was given motivational interviewing.The illness perception,self-perceived burden and self-management ability before and after intervention were compared between the two groups.Results After intervention,the scores of illness perception and self-management ability of the two groups were higher than those before intervention,the scores of self-perceived burden of the two groups were lower than those before intervention,and the differences were statistically significant (P<0.05).After intervention,the scores of illness perception and self-management ability of the experimental group were higher than those of the control group,the score of self-perceived burden of the experimental group was lower than that of the control group,and the differences were statistically significant (P<0.05).Conclusion Motivational interviewing intervention in AMI patients with PCI can improve the illness perception,increase the self-management ability,decrease the self-perceived burden and improve the prognosis and recovery.
2020 Vol. 27 (30): 187-189转193 [Abstract] ( 16 ) HTML (34 KB)  PDF  (0 KB)  ( 11 )
190 Application of scenario simulation combined with mind mapping teaching in the training of core nursing system for N1 nurses
LUO Xiao-yan ;LI Qin-hua ;SU Xiu-mei ;LI Xue-hong ;DENG Chun-hong
Objective To explore the application of scenario simulation combined with mind mapping teaching in the training of core nursing system for N1 nurses.Methods A total of 64 N1 nurses who worked in our hospital from June 2017 to June 2019 were selected as the research objects and divided into the control group and the research group according to different training methods,with 32 cases in each group.The control group was trained by traditional teaching method,while the research group was trained by scenario simulation combined with mind mapping teaching.The training satisfaction scores,qualification rates of theoretical assessment,single operation assessment and comprehensive quality assessment of the two groups after 5 months training were compared.Results The training satisfaction score of the research group was higher than that of the control group,and the difference was statistically significant (P<0.05).There were no statistically significant differences in the qualification rates of the oretical assessment,single operation assessment and comprehensive quality assessment of the two groups before training (P>0.05).The qualification rates of the oretical assessment,single operation assessment and comprehensive quality assessment of the two groups after training were higher than those before training,and the differences were statistically significant (P<0.05).After training,the qualification rates of theoretical assessment,single operation assessment and comprehensive quality assessment of the research group were higher than those of the control group,and the differences were statistically significant (P<0.05).Conclusion The application of scenario simulation combined with mind mapping teaching in the core nursing system training for N1 nurses obtains an ideal effect,which can effectively enhance the initiative in learning,improve the satisfaction with teaching and training,and deepen the understanding of nurse on thecore nursing system.It is worthy of clinical promotion and application.
2020 Vol. 27 (30): 190-193 [Abstract] ( 13 ) HTML (35 KB)  PDF  (0 KB)  ( 9 )
194 Application of micro-class combined with PBL teaching in the clinical teaching of surgical cholelithiasis for standardized training students
YU Ya-bin
 Objective To observe the application effect of micro-class combined with problem-based learning (PBL)teaching model in the teaching of cholelithiasis for standardized training students (STSs).Methods A total of 64 STSs who rotated in department of hepatobiliary surgery of our hospital from September 2015 to September 2019 were selected as the research objects,and they were divided into the control group and the experimental group according to the random number table method,with 32 cases in each group.The experiment group was given micro-class and PBL teaching,while the control group was given traditional teaching method.After the rotation,scores of theoretical examination,practical skills test and comprehensive capacityof STSs were compared.Results The scores of theoretical examination and practical skills test of the experimental group ([92.94±2.98] points,[92.31±1.91] points) were higher than those of the control group ([87.75±3.84] points,[89.13±2.52] points),and the differences were statistically significant (P<0.05).The scores of self-learning ability,learning interest,practical ability,thinking ability and understanding ability of the experimental group were higher than those of the control group,and the differences were statistically significant(P<0.05).Conclusion The combination of micro-class and PBL teaching can improve the theoretical and practical performance of STSs and enhance the comprehensive ability of disease diagnosis and treatment,which is worthy of promotion and application.
2020 Vol. 27 (30): 194-196 [Abstract] ( 13 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
197 Application value of PACS combined with PBL in nuclear medicine teaching
WANG Xu-fu ;LIU Bin ;LIU Xin-feng; ZHANG Qin
Picture archiving and communicating system (PACS) is used in the medical field mainly for the collection,storage,transmission and management of medical image information.Problem-based learning (PBL) is a new type of teaching method.It is problem-oriented and takes students as the main body.The combination of the two methods provides a more advanced method for nuclear medicine teaching,which is conducive to improve learning interest and learning efficiency of students and have great value in nuclear medicine teaching.This paper investigates the value of PACS combined with PBL in nuclear medicine teaching,starting with the common problems of nuclear medicine teaching,then analyzes the characteristics and application significance of PACS combined with PBL,and finally puts forward the application prospect.
2020 Vol. 27 (30): 197-199 [Abstract] ( 18 ) HTML (31 KB)  PDF  (0 KB)  ( 10 )
200 Application effect of 3D printing model in the teaching of spinal surgery
CHENG Xiao-fei ;XU Chen ;GAN Yao-kai ;YANG Er-zhu ;HUANG Ze-nan ;ZHAO Jie
Objective To explore the application effect of three dimensions (3D) printing model in the teaching of spinal surgery.Methods A total of 32 students who received standardization training in our hospital from September 2015 to September 2018 were randomly divided into the experimental group and the control group by lottery method,with 16 students in each group.The same teaching content in two groups was the spinal disease which was required by the resident standardized training syllabus.The experimental group was taught with the 3D printing model,and the control group was taught with traditional methods.The theoretical test scores and total teaching satisfaction of the two groups were compared.Results The theoretical test scores and total teaching satisfaction of the experimental group were higher than those of the control group,and the differences were statistically significant (P<0.05).Conclusion The 3D printing model can effectively improve the theoretical test scores of students and increase the teaching satisfaction,which is worth of further promoting.
2020 Vol. 27 (30): 200-202转206 [Abstract] ( 15 ) HTML (33 KB)  PDF  (0 KB)  ( 12 )
203 Application of hand exercise in nursing of patients with rheumatoid arthritis treated by modified Taohong Siwu Decoction fumigation and washing
HUANG Hong ;FANG Qun; LI Ying
 Objective To investigate the application effect of hand exercise in nursing of patients with rheumatoid arthritis (RA) treated by modified Taohong Siwu Decoction fumigation and washing.Methods A total of 60 patients with RA who were admitted to our hospital from June 2018 to December 2019 were selected as the research subjects,and they were divided into control group (n=30) and observation group (n=30) according to random number table method.The control group was given modified Taohong Siwu decoction fumigation and washing combined with routine nursing,and observation group was given modified Taohong Siwu Decoction fumigation and washing combined with hand exercise.The morning stiffness time,joint range of motion,pain Degree,activities of daily living and nursing satisfaction were compared between two groups.Results There were no statistical differences in the morning stiffness time,joint range of motion and score of visual analogue scale (VAS) between two groups before intervention (P＞0.05).After intervention,the morning stiffness time of observation group was shorter than that of control group,the VAS score of observation group was lower than that of control group,and the joint range of motion in observation group was higher than that in control group,the differences were statistically significant (P<0.05).After intervention in same group,the morning stiffness time was shorter than that before intervention,and the joint range of motion and VAS score were lower than those before intervention (P<0.05).Before intervention,there were no statistical differences in the scores of Barthel index (BI) and nursing satisfaction between two groups (P＞0.05),and after intervention,the scores of BI and nursing satisfaction in observation group were higher than those in control group,the differences were statistically significant (P<0.05).After intervention,the scores of BI and nursing satisfaction in same group were higher than those before intervention,the differences were statistically significant (P<0.05).Conclusion Hand exercise in nursing of patients with RA treated by modified Taohong Siwu Decoction fumigation and washing has better application effects,it can improve joint symptoms,shorten morning stiffness time,relieve pain degree,and increase activities of daily living and nursing satisfaction.
2020 Vol. 27 (30): 203-206 [Abstract] ( 14 ) HTML (35 KB)  PDF  (0 KB)  ( 14 )
207 Clinical effect observation of intravenous indwelling on the working efficiency of nurses
CAO Run-qin ;WANG Shu-feng ;HUANG Xue-qin
Objective To explore the effect of intravenous indwelling on the working efficiency of nurses.Methods From January 2019 to January 2020,120 patients with postoperative nasal polyps in our hospital were divided into observation group (60 cases) and control group (60 cases) by the random number table method.In the observation group,intravenous indwelling needle infusion was used,while in the control group,disposable steel needle infusion was used.The working efficiency,patients′ negative psychology and patients′ nursing satisfaction of the two groups were compared.Results The total effective rate of nurses in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05).The scores of anxiety and depression in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).The nursing satisfaction of patients in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion Intravenous indwelling needle infusion can improve nurses′ working efficiency,patients′ nursing satisfaction and reduce patients′ negative psychology and other adverse consequences,which is worthy of clinical application.
2020 Vol. 27 (30): 207-209 [Abstract] ( 15 ) HTML (32 KB)  PDF  (0 KB)  ( 11 )
210 Study on the predictive nursing intervention to reduce complications of 3D laparoscopic radical cervical cancer
ZHANG Juan ;LIU Yu; ZHENG Li-fang ;LIANG Jin-yu; YANG Qiong ;LI Zhen
Objective To explore the application effect of predictive nursing intervention on patients undergoing 3D laparoscopic radical cervical cancer surgery.Methods From September 2017 to September 2019,60 patients undergoing 3D laparoscopic radical cervical cancer treated in our hospital were selected.Based on the random number table method,patients were divided into two groups,30 cases in each group.The control group received routine nursing.Based on this,the experimental group added the predictive nursing intervention.The incidence of postoperative complications,urinary indwelling time and residual urine volume,length of hospital stay,and nursing satisfaction between two groups were compared.Results The total incidence of postoperative complications in the experimental group was lower than that in the control group (P<0.05);the urinary indwelling time and hospital stay in the experimental group were shorter than those in the control group,and the residual urine volume was less than the control group,the satisfaction of the experimental group was higher than that of the control group,the differences were statistically significant(P<0.05).Conclusion In the 3D laparoscopic radical cervical cancer nursing,combined with predictive nursing intervention,it can not only reduce postoperative complications,reduce residual urine volume,shorten urinary indwelling time and hospitalization time,but also improve nursing satisfaction,which is worthy of clinical promotion and application.
2020 Vol. 27 (30): 210-212 [Abstract] ( 12 ) HTML (32 KB)  PDF  (0 KB)  ( 12 )
213 Application effect of psychological rehabilitation in patients with coronary heart disease after coronary intervention
QIU Jing-wei; LI Xiao-yan; YE Fei

 Objective To analyze the application effect of psychological rehabilitation in patients with coronary heart disease (CHD) after coronary intervention.Methods A total of 58 patients with CHD who underwent coronary intervention from April 2017 to June 2018 in our hospital were divided into observation group and control group according to the sequence of hospital admission,with 29 cases in each group.Both groups were treated with drugs based on the conventional guideline,and simultaneously controlled the risk factors of CHD by scientific lifestyle,and exercise guidance was conducted according to the patient′ s specific condition.In the observation group,psychological rehabilitation was added.The scores of rehabilitation knowledge,self-care ability,anxiety,and quality of life before and after nursing in both groups were compared.Results In the observation group,the scores of rehabilitation knowledge of CHD and self-care ability were higher than those of the control group,and the differences were statistically significant (P<0.05).1 year after nursing,the anxiety score of the observation group was lower than that of the control group,the quality of life score of the observation group was higher than that of the control group,and the differences were statistically significant (P<0.05).Conclusion Drug therapy,scientific lifestyle intervention and psychological rehabilitation are conducive to the rehabilitation of patients with CHD.
2020 Vol. 27 (30): 213-215 [Abstract] ( 14 ) HTML (32 KB)  PDF  (0 KB)  ( 8 )
216 Application value of therapeutic communication based on humanistic care in patients undergoing laparoscopic surgery for ectopic pregnancy
GUO Ji-rui ;CHEN Wei-zhu; HOU Zhi-rong
Objective To explore the clinical effect of therapeutic communication based on humanistic care on laparoscopic patients with ectopic pregnancy.Methods A total of 132 patients with ectopic pregnancy who underwent laparoscopic surgery from January 2017 to January 2019 in our hospital were divided into control group (68 cases,routine nursing) and observation group (64 cases,adding based on humanistic care) by the random number table method.The anxiety,depression,sleep treatment scores,surgical related indicators and postoperative complications were observed in the two groups.Results After the intervention,the self-rating depression scale (SDS) score,the self-rating anxiety scale (SAS) score and Pittsburgh sleep quality (PQSI) score of the observation group were lower than those of the control group,and the differences were statistically significant (P<0.05).The amount of intraoperative bleeding in the observation group was less than that in the control group,and the operation-related index time was shorter than that in the control group,and the differences were statistically significant (P<0.05).The total incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion Therapeutic communication based on humanistic care can significantly improve the negative emotions of patients undergoing laparoscopic ectopic pregnancy,promote postoperative rehabilitation,and reduce postoperative complications.It is worthy of promotion.
2020 Vol. 27 (30): 216-218转222 [Abstract] ( 13 ) HTML (34 KB)  PDF  (0 KB)  ( 10 )
219 Application effect of continuous nursing service in lower limb arteriosclerosis obliterans patients with interventional therapy
YE Lu-juan ;LIU Zhen-ying; DONG Jing-xiu ;LIU Yan
 Objective To investigate the application effect of continuous nursing service in lower limb arteriosclerosis obliterans (ASO) patients with interventional therapy.Methods A total of 82 patients with ASO admitted to our hospital from November 2017 to November 2019 were selected as the research subjects.All the patients were divided into control group (41 cases) and observation group (41 cases) according to the random number table method.The control group was given routine nursing,while the observation group was given continuous nursing based on the control group.The scores of exercise of self-care agency scale (ESCA),quality of life questionnaire-core 30 (QLQ-C30) on discharge and after discharge for 6 months,and the recurrence of disease were compared between the two groups.Results The scores of ESCA and QLQ-C30 in the observation group were higher than those in the control group,with statistically significant differences (P<0.05).No reocclusion occurred in the observation group,and the incidence of reocclusion in the control group was 14.63%;the incidence of restenosis in the observation group was 2.44%,which was lower than 19.51% in the control group,and the differences were statistically significant (P<0.05).Conclusion Continuous nursing service in ASO patients with interventional therapy can effectively increase the level of self-management,improve quality of life,and reduce the recurrence of the disease.
2020 Vol. 27 (30): 219-222 [Abstract] ( 14 ) HTML (35 KB)  PDF  (0 KB)  ( 9 )
223 Application effect of evidence-based rehabilitation nursing in elderly patients with cerebral infarction with constipation
CONG Yuan-yuan
Objective To evaluate the application effect of evidence-based rehabilitation nursing in elderly patients with cerebral infarction (CVA) and constipation.Methods From February 2017 to May 2018,60 patients with constipation admitted to our hospital during the period of CVA in elderly patients were selected as the research objects.They were divided into observation group (n=30) and control group (n=30) following the blind computer test.The control group used conventional rehabilitation nursing methods,the observation group was given evidence-based rehabilitation nursing.The total nursing efficiency,nursing satisfaction and constipation frequency of the two groups were compared.Results The total nursing efficiency of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The nursing satisfaction in the observation group was higher than that in the control group,and the constipation frequency was lower than that in the control group,with statistical differences (P<0.05).Conclusion Elderly patients with CVA and constipation with evidence-based rehabilitation nursing method,nursing efficiency is higher,constipation symptoms are significantly improved,nursing satisfaction is higher,worthy of clinical application.
2020 Vol. 27 (30): 223-225 [Abstract] ( 15 ) HTML (33 KB)  PDF  (0 KB)  ( 10 )
226 Application effect of clinical nursing pathway in the radical gastrectomy patients
QIN Ping
 Objective To analyze the effect of clinical nursing pathway (CNP) in patients with radical gastrectomy.Methods A total of 200 patients with gastric cancer admitted to our hospital from January 2017 to December 2019 were selected.According to the computer random sequence grouping method the patients were divided into control group and CNP group,100 cases in each group.The control group received routine nursing intervention,the CNP group received CNP intervention.The rehabilitation indexes,quality of life,complications and nursing needs of the two groups were compared.Results The time of anal exhaust,gastric tube extraction,out-of-bed activity and hospitalization in CNP group were shorter than those in control group,the differences were statistically significant (P<0.05).The quality of life QOL score of CNP group was higher than that of control group,the difference was statistically significant (P<0.05).The total incidence of complications of CNP group was lower than that of control group,the difference was statistically significant (P<0.05).The satisfaction rate of life nursing,pain nursing,emotional nursing,rehabilitation nursing,diet nursing,humanistic care and personalized needs in CNP group was higher than that in the control group,the differences were statistically significant (P<0.05).The satisfaction rate of basic nursing care in CNP group was not statistically significant difference compared with the control group (P>0.05).Conclusion CNP can improve the quality of life of patients after radical gastrectomy,reduce complications,and promote patients′ recovery.
2020 Vol. 27 (30): 226-228 [Abstract] ( 22 ) HTML (32 KB)  PDF  (0 KB)  ( 8 )
229 Application effect of evidence-based nursing in patients with dilated cardiomyopathy
SHI Yi-liang
Objective To investigate the application effect of evidence-based nursing in patients with dilated cardiomyopathy.Methods A total of 76 patients with dilated cardiomyopathy who were admitted to the hospital from June 2017 to June 2019 were selected as the research subjects,and they were divided into control group (38 cases) and observation group (38 cases) according to random number table.The control group received routine nursing,and the observation group took evidence-based nursing.The cardiac function,mastery degree of disease and quality of life were compared between the two groups.Results After intervention,the left ventricular ejection fraction (LVEF) and 6-minute walking test in two groups were higher than those before intervention,and the above indexes in observation group were higher than those in control group,the differences were statistically significant (P<0.05);after intervention,the score of each dimension of mastery degree of disease knowledge questionnaire in observation group was higher than that in control group,and the differences were statistically significant (P<0.05);after intervention,the physical,psychological,independence,social relationship,environment,spiritual/faith scores in the two groups were higher than those before intervention,and the above scores in observation group were higher than those in control group,the differences were statistically significant (P<0.05).Conclusion Evidence-based nursing for patients with dilated cardiomyopathy can increase LVEF and walking distance,thus improving the cardiac function;and it can increase the mastery degree of disease knowledge and the level of quality of life,which has better clinical intervention effects.
2020 Vol. 27 (30): 229-231转235 [Abstract] ( 12 ) HTML (33 KB)  PDF  (0 KB)  ( 14 )
232 Effect of clinical nursing pathway on improved PICC catheterization in patients with spastic paralysis in department of neurology
ZHENG Xiao-chun; FAN Yu-ying; DU Ai-hong; MA Hong-yan
Objective To explore the effect of clinical nursing pathways (CNP) in neurological spastic paralysis patients with improved peripherally inserted central catheter (PICC).Methods From January to December 2019,a total of 102 patients with spastic paralysis admitted to the department of neurology of our hospital were selected,and the patients were divided into a study group (n=51) and a control group (n=51) using a random number table method.The control group adopted the routine nursing pathway of PICC under the guidance of B-ultrasound,and the study group adopted the modified PICC catheterization CNP under the guidance of B-ultrasound.The success rate of a puncture,the catheterization time,the healing of the puncture point,the number of dressing changes in one week,and the incidence of complications during catheter indwelling were compared between the two groups.Results The success rate of a puncture in the study group was higher than that of the control group,and the catheter placement time was shorter than that of the control group,the differences were statistically significant (P<0.05).The puncture point healing rate of the study group was higher than that of the control group,and the difference was statistically significant (P<0.05).The number of dressing changes in one week after puncture was fewer than that of the control group,the difference was statistically significant (P<0.05).The incidence of complications after PICC catheterization in the study group was lower than that of the control group,and the difference was statistically significant (P<0.05).Conclusion The application of modified PICC catheterization CNP in neurological spastic paralysis patients can effectively improve the success rate of a puncture,facilitate the healing of the puncture point,reduce the incidence of PICC complications,and improve the quality of care.
2020 Vol. 27 (30): 232-235 [Abstract] ( 15 ) HTML (35 KB)  PDF  (0 KB)  ( 11 )
236 Application effect of SBAR communication mode in patients with syncope syndrome by venous blood collection
JIANG Chun-ying ;ZHANG Hua-xiu
Objective To investigate the application effect of SBAR communication mode in patients with syncope syndrome by venous blood collection.Methods From January 2018 to January 2019，400 patients in our hospital outpatient with venous blood collection dizziness needle were selected and divided into control group and observation group by random number table method,200 cases in each group.The control group used routine communication mode to communicate with patients,the observation group used SBAR communication mode to communicate with patients according to situation (S),bbackground (B),assessment (A),recommendation (R) procedure,the anxiety degree,satisfaction with the communication between nurses and patients and the adverse event of venous blood collection between the two groups were compared.Results After blood collection,the anxiety degree of the patients in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05),the total satisfaction of the patients in the observation group was higher than that in the control group (P<0.05),and the total incidence of adverse event in the observation group was lower than that in the control group， the difference was statistically significant (P<0.05).Conclusion The SBAR communication mode can significantly improve the stress and anxiety of patients,improve the satisfaction of patients with the communication,reduce the occurrence of the adverse event of venous blood collection,and protect the patients′ safety,improve the quality of nursing care,and make the patients recover at an early date.
2020 Vol. 27 (30): 236-239 [Abstract] ( 13 ) HTML (36 KB)  PDF  (0 KB)  ( 13 )
240 Exploration on continuous improvement of management quality of fever patients in maternal and child hospital during the prevention and control of COVID-19 epidemic situation
XU Feng ;WANG Xiao-juan; WANG Yan; MA Jin-ge
The epidemic situation of COVID-19 has spread throughout the country.In order to do a good job in the prevention and control of pneumonia,maternal and children′s hospitals have started independent infection buildings,far away from outpatient and inpatient buildings,and carry out professional training for doctors and triage nurses.Continuous quality improvement was carried out in the aspects of pre-examination triage,fever clinic,isolation ward location and post responsibilities,work flow,personnel deployment,training and assessment,quality control,personal protection of pre-examination triage personnel,etc.It ensures the smooth progress of the task of prevention and early warning institutions for the prevention and early warning of infectious diseases,so as to achieve the effect of centralized diagnosis,treatment and management of febrile patients and improve the environment of patients,to prevent the occurrence of nosocomial infection.
2020 Vol. 27 (30): 240-243 [Abstract] ( 18 ) HTML (34 KB)  PDF  (0 KB)  ( 10 )
244 Efect of blood transfusion quality control system on clinical blood transfusion quality
TAN Xiong-rui; LI Yi-jian; CHEN Yi-ming
Objective To explore the influence of blood transfusion quality control system on clinical blood transfusion quality.Methods A total of 210 patients with blood transfusion admitted to Foshan City Center Blood Station from February 2017 to February 2018 were selected as the research subjects.They were divided into control group (n=105)and observation group (n=105) according to the random number table method.The control group received routine blood transfusion,the observation group was managed by blood transfusion quality control system.Blood transfusion quality indicators (transfusion index compliance rate,accuracy of application form filling,complete rate of pre-transfusion check,complete rate of transfusion records),component blood volume (red blood cells,plasma,platelets) in transfusion,and failure rate of signing of application form ( forgot to fill in blood type,forget to fill in blood routine,forget to fill in scheduled blood transfusion time,forget to sign the physician,forget to sign the senior physician,fill incomplete consent rate of blood transfusion consent,fill in failure rate of blood transfusion consent) between two groups were compared.Results The compliance rate of the blood transfusion index in the observation group was 93.33%,the accuracy of filling in the application form was 85.71%,the complete rate of the pre-transfusion check was 95.24%,and the complete rate of the blood transfusion record was 96.19%,which were higher than those of the control group of 66.67%,65.71%,76.19%,75.24%,the differences showed statistical significance (P<0.05).The amount of red blood cells and plasma in the observation group was less than that in the control group,and the differences were statistically significant(P<0.05).The platelet treatment volume in the observation group was 1245±0.10,higher than that in the control group(820±0.05),and the difference was statistically significant (P<0.05).The unqualified rate in the observation group after signing the application form was 7.62%,which was lower than the control group of 18.09%,the difference was statistically significant (P<0.05).Conclusion Applying the quality control system to the blood transfusion process in clinic can improve its quality and is worth applying.
2020 Vol. 27 (30): 244-246 [Abstract] ( 14 ) HTML (33 KB)  PDF  (0 KB)  ( 9 )
247 Relevant problems and countermeasures in administrative management of our hospital
BIAN Yu-hang

Administration is like a rich neural network that connects all aspects of the hospital.To improve the hospital′s operation and service level,we must start from the perspective of administrative reform.This thesis summarizes a large number of relevant literature and problems in the administration of the hospital,such as insufficient information construction,irrational management structure,weak system implementation supervision,lack of management accounting thinking,insufficient performance evaluation incentives,and lack of brand culture.It specifically involves the fields of information,people,finance,and things,and finds the underlying causes to form a scientific solution strategy,hoping to promote the administrative reform of the hospital.
2020 Vol. 27 (30): 247-249 [Abstract] ( 13 ) HTML (34 KB)  PDF  (0 KB)  ( 8 )
250 Strategies and measures for prevention and control of the COVID-19 in medical institutions
JIANG Rong; XIE Hua-rong; Duan Yong-sheng
The ongoing COVID-19 outbreak has spread rapidly on a global scale and posed great threat to global public health.The virus mainly spreads via aerial droplets,direct contact and aerosol transmission.Patients and medical staff involved in the treatment all have the potential risk of cross infection in hospitals.Therefore,it was very important to take appropriate measures to prevent and control infection.The Fifth People′s Hospital of Chongqing is designated hospitals for COVID-19 treatment.Based on our former experience in preventing and controlling the COVID-19 in medical institutions,this essay mainly introduces some strategies and measures,including ward planning,staff training,disinfection isolation,medical waste management,etc.We implements various prevention and control measures strictly,which can reduce the risk of the spread of the new coronary pneumonia virus,lower the number of infectious patients and medical staff,prevent the occurrence of hospital infections,and achieve ″zero infection″ goal in the hospital.
2020 Vol. 27 (30): 250-252 [Abstract] ( 16 ) HTML (31 KB)  PDF  (0 KB)  ( 12 )
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