无创呼吸机治疗慢性阻塞性肺疾病合并睡眠呼吸暂停低通气综合征的效果

Abstract
Figure/Table
References (16)
Related Citation (15)

Download: PDF (0 KB) HTML (48 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To evaluate the effect of noninvasive ventilator in the treatment of chronic obstructive pulmonary disease (COPD) with sleep apnea hypopnea syndrome (SAHS).Methods A total of 70 patients with COPD and SAHS admitted to our hospital from October 2014 to October 2019 were selected as the research objects.They were divided into observation group (n=35) and control group (n=35) according to method of drawing lots for random grouping.The observation group was treated with non-invasive ventilator,while the control group was treated with conventional therapy.The values of percutaneous oxygenation (SaO2),bicarbonate (HCO3-),pH,partial pressure of carbon dioxide (PCO2)oxygen partial pressure (PO2),forced expiratory volume in first second (FEV1)/forced vital capacity (FVC),ratio of FEV1 to predicted value and therapeutic effect were compared between the two groups.Results There were statistically significant differences in the observation group before and after treatment in SaO2,blood HCO3-,PCO2,and PO2 (P<0.05);there was no significant difference in pH before and after treatment (P＞0.05);there was significant difference in SaO2 before and after treatment in the control group (P<0.05),there were significant differences after treatment in blood HCO3-,pH,PCO2,and PO2 compared with before treatment (P<0.05).Patients in the observation group after treatment,SaO2,blood HCO3-,pH,PCO2,and PO2 were better than those in the control group,and the differences were statistically significant (P<0.05).The comparison of FEV1/FVC,FEV1% before treatment between the two groups was not statistically significant (P＞0.05);in the observation group after treatment,the predicted values of FEV1/FVC and FEV1% were higher than those in the control group,and the differences were statistically significant (P<0.05).The peak inspiratory pressure and tidal volume in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).The total effective rate in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion The non-invasive ventilator therapy for COPD with SAHS can significantly improve the arterial blood gas,pulmonary function and mechanical ventilation parameters of the patients,which has good application effect and promising development.

Key words： Non-invasive ventilator Treatment Chronic obstructive pulmonary disease with sleep apnea hypopnea syndrome Effect

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	CHEN Shao-shan
	LI Ju-heng
	LIN Shi-jun

Cite this article:

CHEN Shao-shan,LI Ju-heng,LIN Shi-jun. Effect of non-invasive ventilator in the treatment of chronic obstructive pulmonary disease with sleep apnea hypopnea syndrome[J]. 中国当代医药, 2020, 27(30): 47-50.

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2020/V27/I30/47

[2]	蔡颖如，赖天文，李文.慢性阻塞性肺疾病合并睡眠呼吸暂停低通气综合征的治疗进展[J].国际呼吸杂志，2019，39（7）：542-546.
[1]	王品，冯文杰，申方臣.无创呼吸机联合穴位埋线治疗COPD合并Ⅱ型呼吸衰竭急性期15例临床研究[J].江苏中医药，2018，50（6）：61-63.
[3]	石婷.无创呼吸机治疗慢性阻塞性肺疾病合并呼吸衰竭临床价值评价[J].中外医学研究，2019，17（16）：133-134.
[4]	郭海健，廖新良.无创呼吸机治疗慢性阻塞性肺疾病合并睡眠呼吸综合征的疗效[J].实用临床医药杂志，2018，22（21）：33-35，39.
[5]	刘冰，张书永.平喘止鼾汤治疗慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停低通气综合征36例临床观察[J].河北中医，2019，41（7）：1005-1009.
[6]	徐光辉，王学忠，张梁.探讨双水平无创正压呼吸机治疗阻塞性睡眠呼吸暂停低通气综合征合并慢性阻塞性肺疾病的疗效分析[J].当代医学，2018，24（7）：68-70.
[7]	李琴，陈贵华，虞乐华，等.肺康复治疗慢性阻塞性肺疾病急性加重期疗效的系统评价[J].中华物理医学与康复杂志，2019，41（4）：299-304.
[8]	申丽旻，何聪，任珊，等.体外膈肌起搏对慢性阻塞性肺疾病机械通气患者的治疗效果评价[J].河北医药，2019，41（19）：2898-2901.
[9]	王红娟，郭红荣，鲍敏，等.支气管镜联合无创正压通气治疗慢性阻塞性肺疾病并呼吸衰竭的疗效[J].中国老年学杂志，2016，36（2）：377-379.
[10]	聂晓红，熊曙光，王晓虹，等.体质量指数对慢性阻塞性肺疾病急性加重期患者治疗反应性及气道黏液高分泌的影响[J].中国急救医学，2019，39（4）：332-337.
[11]	谷刚，田科.支气管镜联合无创正压通气治疗慢性阻塞性肺疾病并呼吸衰竭的临床疗效[J].中国老年学杂志，2016，36（3）：659-660.
[12]	谷桂芳，程鹤，程玉花，等.一例慢性阻塞性肺疾病患者抗焦虑抑郁治疗联合下肢肌肉功能锻炼的应用成效[J].护士进修杂志，2018，33（13）：1242-1244.
[13]	黄慧婷，周游，刘小虹，等.肺康颗粒对慢性阻塞性肺疾病稳定期患者肺功能及生活质量的影响[J].广州中医药大学学报，2019，36（9）：1305-1311.
[14]	刘莉丽，孟建斌，王文欣，等.纳洛酮联合无创正压通气治疗慢性阻塞性肺疾病合并呼吸衰竭的临床研究[J].中国临床药理学杂志，2016，32（16）：1443-1445.
[15]	李沁，陈登科.唑来膦酸联合钙剂治疗老年慢性阻塞性肺疾病患者骨质疏松症的临床疗效[J].中国骨质疏松杂志，2018，24（2）：222-225.
[16]	陈方榕.BiPAP 呼吸机治疗慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停低通气综合征的效果分析[J].世界睡眠医学杂志，2019，6（5）：652-655.