甲状腺全切除术对原发性甲状腺功能亢进合并甲状腺癌患者甲状旁腺激素、血钙水平的影响

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Abstract Objective To investigate the influence of total thyroidectomy on parathyroid hormone (PTH) and blood calcium levels in patients with primary hyperthyroidism and thyroid cancer.Methods A total of 60 patients with primary hyperthyroidism combined with thyroid cancer who were admitted to our hospital from February 2018 to December 2019 were selected as the research subjects.All the selected patients were divided into the control group (30 cases)and the observation group (30 cases) according to random number table method.The control group underwent subtotal thyroidectomy,and the observation group was treated with total thyroidectomy.The clinical indexes,thyroid hormone,blood calcium level,serum level and complications were compared between the two groups.Results The operation time,intraoperative bleeding volume,and hospital stays were compared between the two groups,and the differences were not statistically significant (P>0.05).The levels of total triiodothyronine (TT3),total thyroxine (TT4),PTH and blood calcium were compared between the two groups before surgery,and the differences were not statistically significant (P>0.05).The levels of TT3 and TT4 in the two groups after surgery were higher than those before surgery,the levels of PTH and blood calcium after surgery were lower than those before surgery,the levels of TT3 and TT4 in the observation group after surgery were higher than those in the control group,and the levels of PTH and blood calcium in the observation group after surgery were lower than those in the control group,and the differences were statistically significant (P<0.05).The IL-17 levels of the two groups after surgery were lower than those before operation,and the IL-35 levels of the two groups after surgery were higher than those before operation,the level of IL-17 of the observation group after surgery was lower than that of the control group,while the IL-35 level of the observation group after surgery was higher than that of the control group,and the differences were statistically significant (P<0.05).There was no statistical difference in the total incidence of postoperative complications between the two groups (P>0.05).Conclusion Total thyroidectomy in the treatment of patients with primary hyperthyroidism and thyroid cancer decreases the levels of PTH and blood calcium,but it can regulate the levels of inflammatory factors,which has certain safety.

Key words： Primary hyperthyroidism Thyroid cancer Total thyroidectomy Parathyroid hormone Blood calcium

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	Articles by authors
	WANG Xuan-kai
	LI Xian-yong
	LIN Guan-mao
	HONG Hui
	LI Zhi-rong
	ZHAN Dong-zai

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WANG Xuan-kai,LI Xian-yong,LIN Guan-mao, et al. Influence of total thyroidectomy on parathyroid hormone and blood calcium levels in patients with primary hyperthyroidism and thyroid cancer[J]. 中国当代医药, 2020, 27(30): 106-109.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2020/V27/I30/106

[3]	菅雁兵，王冰，彭君，等.原发性甲状腺功能亢进合并甲状腺癌的术式探讨[J].中华内分泌外科杂志，2019，13（4）：269-272.
[1]	汪丽平，蔡成福，刘存山.原发性甲状腺功能亢进症并甲状腺癌的临床分析[J].中国基层医药，2019，26（14）：1686-1688.
[2]	信学礼，宋德余，王成君，等.全甲状腺切除术治疗原发性甲亢合并甲状腺癌对患者预后的影响[J].实用医学杂志，2019，35（11）：1809-1812.
[4]	黎东伟，李君久，熊秋华，等.腔镜甲状腺次全切除术在原发性甲状腺功能亢进外科治疗中的应用[J].中国微创外科杂志，2016，16（8）：749-751.
[5]	孙小亮，鲁瑶，杨猛，等.腔镜下改良甲状腺次全切除术治疗原发性甲状腺功能亢进[J].中国微创外科杂志，2018，18（2）：118-120.
[6]	中华医学会内分泌学分会《中国甲状腺疾病诊治指南》编写组.中国甲状腺疾病诊治指南——甲状腺功能亢进症[J].中华内科杂志，2007，46（10）：876—882.
[7]	李志锋，刘进忠，卞永生.甲状腺功能亢进合并甲状腺癌的诊治[J].现代肿瘤医学，2014，22（2）：299-300.
[8]	郝国强，邢壮杰，邓芝徽，等.继发性甲状旁腺功能亢进行甲状旁腺全切除术后低钙血症的防治[J].安徽医药，2019，23（10）：1998-2000.
[9]	黎东伟，李君久，熊秋华，等.腔镜甲状腺切除术在原发性甲亢外科治疗中的应用研究[J].腹腔镜外科杂志，2016，21（9）：657-660.
[10]	赵瑞敏，黄健华，朱云，等.甲状腺部分或全切除术后患者的嗓音主客观检测结果分析[J].听力学及言语疾病杂志，2019，27（2）：189-192.
[11]	彭亚，柳岸，彭小伟.经口腔前庭内镜甲状腺癌切除术治疗甲状腺癌的临床疗效[J].癌症进展，2019，17（13）：1531-1533.
[12]	陈勇，徐宙.甲状腺切除术后抗甲状腺球蛋白抗体水平对术前甲状腺球蛋白阴性的分化型甲状腺癌患者预后的预测价值[J].广西医学，2019，41（10）：1251-1254.
[13]	刘钟华.甲状腺次全切除术治疗结节性甲状腺肿的效果[J].中国当代医药，2018，25（32）：50-52.
[14]	高恒元，许楠，罗勋鹏，等.72例继发性甲状旁腺功能亢进行甲状旁腺次全切除术的治疗分析[J].中国现代普通外科进展，2017，20（9）：684-686.
[15]	吴乔，王姗.改良甲状腺切除术治疗甲亢的疗效及对TSH、T3、T4的影响[J].西南国防医药，2017，27（10）：1085-1087.