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2017 Vol. 24, No. 31
Published: 2017-11-08
 
 
4 Mechanism of Toll-like receptors 3 on heart ischemia/reperfusion injury in rats
WANG Yuan-yuan；CAO Jian； DENG Li
ObjectiveTo investigate the expression of Toll－like receptors 3 and the correlation mechanism of ischemia/ reperfusioninjuryinrats.MethodsTOLL－likereceptor3deficient(TLR3－/－)andwildtype(WT)ratsweresubjected to ischemia/ reperfusion induced by ligation of the left anterior descending coronary artery.Sixty rats were divided into 4 groups: sham－operated group(WT)(n=15),myocardial ischemia/reperfusion group(WT)(n=15),sham－operated group(TLR3－/－) (n=15)and myocardial ischemia/reperfusion group(TLR3－/－)(n=15).The MDA,GSH,CK－MB,LVEDV,LVESV,LVEF and the expression of TLR3,NF－κB in four groups were detecte.ResultsThe level of MDA [(9.72±6.15)nmol/L],CK－MB [(1075.76±3.27)U/L]in myocardial ischemia/reperfusion group(TLR3－/－)were lower than the myocardial ischemia/reperfusion group(WT)[(14.85±5.2)nmol/L，(1842.16±4.28)U/L],the value of GSH in myocardial ischemia/reperfusion group(TLR3－/－)was higher than the myocardial ischemia/reperfusion group(WT),and the differences were statistically significant(P＜0.05).The LVEDV [(602.0±2.7)μl],LVESV [(516.0±2.9)μl]of the myocardial ischemia/reperfusion group (TLR3－/－)were lower than the myocardial ischemia/reperfusion group(WT)[(702.0±4.5)μl,(516.0±2.9)μl],the LVEF[(42.0±2.8)%]of the myocardial ischemia/reperfusion group (TLR3－/－)was higher than the myocardial ischemia/reperfusion group(WT) [(36.0±4.2)%],and the differences were statistically significant(P＜0.05).The expression of TLR3(0.862±0.158), NF－κB(0.786±1.784)of the myocardial ischemia/reperfusion group(WT)were higher than the sham－operated group(WT) (0.315±1.834,0.206±1.924),and the differences were statistically significant(P＜0.05).The expression of TLR3(0.076± 1.52)、NF－κB (0.625±2.824)of the myocardial ischemia/reperfusion group (TLR3－/－)were lower than the myocardial ischemia/reperfusion group(WT),and the differences were statistically significant(P＜0.05).Conclusion The TLR3 deficient is important to reduce myocardial I/R injury,it is related to suppress the inflammatory response by down－regulation of NF－κB signaling pathway.
2017 Vol. 24 (31): 4-07 [Abstract] ( 196 ) HTML (39 KB)  PDF  (0 KB)  ( 44 )
8 Evaluation of short-term outcome of laparoscopic BillrothⅡ distal gastrectomy with Brown anastomosis for distal gastric cancer
SUN Wen-bai；ZHANG Peng-bo；ZHANG Chong；ZHANG Xiu-zhong；REN Ze-qiang
ObjectiveTo investigate the feasibility and value of laparoscopic BillrothⅡ distal gastrectomy with Brown anastomosis in the treatment of distal gastric cancer.MethodsAltogether 90 patients who underwent distal gastrectomy for gastric cancer in our hospital from January 2014 to December 2016 were retrospective analyzed and divided according to the surgeries into laparoscopic group (group A with Brown anastomosis in 30 cases,group B without Brown anastomosis in 30 cases)and laparotomy group (with Brown anastomosis in 30 cases).The age,sex,operation time,incision length,bleeding volume,number of lymph node dissection,postoperative white cell values,postoperative hospitalization time and related complications were compared.ResultsThe operation time of the laparoscopic group was obviously longer than that of laparotomy group,intraoperative bleeding was less than that in the laparotomy group,incision length and postoperative hospitalization time were less than those in the laparotomy group,increasing range of postoperative white blood cells was less than that in the laparotomy group,the use of analgesics was less than that of the laparotomy group,the time of discharge and the time of delivery were earlier than those of the laparotomy group,and the differences were statistically significant(P＜0.01).The incidence of incisional infection and postoperative complications were compared between laparoscopic and laparotomy group,and the differences were statistically significant(P＜0.05).There were significantly more non－reflux in the laparoscopic group A and the laparotomy group than the laparoscopic group B,and the difference was statistically significant(P＜0.05).The number of lymph node dissection and the short－term survival rate in the laparoscopic group were compared with that of the laparotomy group,and the differences were not statistically significant(P＞0.05).ConclusionLaparoscopic BillrothⅡ distal gastrectomy with Brown anastomosis is effective in the treatment of distal gastric cancer and has the advantages of less bleeding,quicker postoperative recovery and less postoperative complications.
2017 Vol. 24 (31): 8-11 [Abstract] ( 226 ) HTML (43 KB)  PDF  (0 KB)  ( 38 )
12 Recent advances in research of Kümmell′s disease
WANG Shao-qian； NIU Lei；WANG Hui
Kümmell′s disease is a rare disease with unclear pathogenesis and diagnosis and its main characteristics is a minor trauma of spinal pain,which may recur,aggravate and progress to kyphosis in the same area after months or years of different lengths of the asymptomatic period.Because of the lack of technology and equipment,the disease has not been paid much attention to in the early stage.Department of orthopedics has not been fully aware of the disease,resulting in missed diagnosis and misdiagnosis of Kümmell′s disease.With the first report of the disease by Kümmell,a German,as well as rapid development of technology,CT,MR,and X-ray imaging studies in recent years,reports and researches on Kümmell′s disease tends to increase.In order to improve the understanding of Kümmell′s disease,this paper make a review of the related research of Kümmell′s disease in combination with clinical experience.
2017 Vol. 24 (31): 12-16 [Abstract] ( 242 ) HTML (60 KB)  PDF  (0 KB)  ( 44 )
17 Study of clinical expression significance of IL-17 in peripheral blood of patients with severe pneumonia
CAI Bi-lin; LIN Gui-hua ;XIE Hua-wen ;CHEN Jun; CHEN Ming-di;ZENG Wen-chi
ObjectiveTo analyze the clinical expression significance of IL－17 in peripheral blood of patients with severe pneumonia.MethodsA total of 100 patients diagnosed as severe pneumonia from January 2015 to January 2016 were selected in our hospital.According to the acute physiology and chronic health evaluationⅡ (APACHEⅡ),they were divided into group A(APACHEⅡ score＞20 points)and group B(APACHEⅡ score≤20 points).Another group of 100 healthy people after physical examinations from the same period was chosen as control group.The body temperature(T),white blood cell(WBC)count,procalcitonin(PCT),blood lactic acid(Lac),and interleukin－17(IL－17)were all tested among three groups.The difference of these outcomes were compared.ResultsT,WBC,PCT,Lac,and IL－17 in group A and B were much higher than those in the control group with statistical differences(P＜0.05).Between group A and B,there was no statistical differences was displayed in T,WBC,PCT,or Lac(P＞0.05),but with regard to IL－17,there was a statistical difference (P＜0.05).ConclusionIL－17 in patients with severe pneumonia is significantly higher than that in the healthy,and the level increases with the exacerbation of disease conditions,which indicates that increase of IL－17 level can reflect the condition of patients.
2017 Vol. 24 (31): 17-19 [Abstract] ( 199 ) HTML (32 KB)  PDF  (0 KB)  ( 84 )
20 Clinical study of Azithromycin combined with Carbocisteine in the treatment of acute tracheo-bronchitis
LIU Xiao-jun
ObjectiveTo study the effect of Azithromycin combined with Carbocisteine in the treatment of acute tracheo－bronchitis.Methods74 patients with acute trachea－bronchialitis treated in our hospital from June 2016 to June 2017 were selected and they were divided into the control group (n=37)and research group (n=37)by drawing lots.In the control group,Azithromycin was used,while in the research group,Azithromycin combined with Carbocisteine was adopted.The duration of clinical symptoms,the occurrence of adverse reactions,and curative effect between the two groups were compared.ResultsIn the research group,duration of clinical symptoms was shorter than that in the control group,and the total effective rate was 94.6%in the research group,which was higher than that in the control group (75.7%),and there was a statistical difference (P＜0.05).There was no statistical difference in the incidence of adverse reactions between the two groups (P＞0.05).ConclusionAzithromycin combined with Carbocisteine t acute tracheobronchitis has a significant clinical effect and can shorten the duration of clinical symptoms for patients,improve symptoms without serious adverse reactions,which has a value application.
2017 Vol. 24 (31): 20-22 [Abstract] ( 211 ) HTML (34 KB)  PDF  (0 KB)  ( 73 )
23 Clinical Study of minimally-invasive cardiac surgery under complete video-assisted thoracoscopy
LAI Zheng-hong； LIU Zi-you ；LUO Juan-juan
ObjectiveTo investigate the clinical effectiveness of minimally－invasive cardiac surgery under complete video－assisted thoracoscopy(cVATS).Methods Altogether a total of 56 patients with congenital heart disease admitted in our hospital from January 2011 to December 2016 were selected as objects of this study and divided into study group and control group according to different treatment methods,28 cases in esch group.The study group were treated with minimally－invasive cardiac surgery under cVATS,while the control group were treated with traditional thoracotomy cardiac surgery.The therapeutic effects of the two groups were compared.ResultsThe duration ofsurgery, cardiopulmonary bypass time and aortic cross－clamping time of study group were longer than those of control group, while the postoperative ICU time,ventilation time,duration of drainage and length of post－operative hospitalization of study group were shorter than those of control group,the differences were statistically significant(P＜0.05).The postoperative thoracic duct drainage and transfusion volume of study group were less than those of control group;pain scores of study group were lower than those of control group and the incision satisfaction was higher than that of control group, the differences were statistically significant(P＜0.05).The incidence of residual leakage and mortality were compared between the two groups,the difference was not statistically significant (P＞0.05).ConclusionCompared with the traditional cardiac surgery,minimally－invasive cardiac surgery under cVATS is a safe and reliable surgery with fewer traumas,less bleeding,less blood transfusion,alleviated postoperative pain,quicker recovery and other features.It significantly reduces the clinical blood volume,which has high popularization value.
2017 Vol. 24 (31): 23-25 [Abstract] ( 187 ) HTML (35 KB)  PDF  (0 KB)  ( 41 )
26 Clinical observation of Levamlodipine Besylate combined with Valsartan in the treatment of essential hypertension
YU Fu-quan
ObjectiveTo study the clinical efficacy of Levamlodipine Besylate combined with Valsartan in the treatment of essential hypertension.Methods100 patients with essential hypertension who were admitted to our hospital from January 2014 to January 2016 were selected as the study subjects.According to the random number table method,the patients were divided into observation group and control group,with 50 cases in each group.The control group was given Valsartan of 80 mg,administered in the morning once a day.The observation group was given Levamlodipine Besylate of 2.5 mg and Valsartan of 80 mg,administered in the morning once a day.The patients were administered for 8 weeks continuously.The clinical efficacy,SBP and DBP levels before and after the treatment and quality of life scores were compared and analyzed between the two groups.ResultsThe total clinical effective rate was 96.00%after treatment in the observation group,which was higher than that in the control group (78.00%),the difference was statistically significant(P＜0.05).The levels of SBP[(112.8±15.2)mmHg]and DBP[(72.8±17.2)mmHg]in the observation group after the treatment were significantly lower than those in the control group[(118.5±13.8),(85.3±15.3)mmHg],the differences were statistically significant(P＜0.05).The scores of life quality after the treatment in the observation group were significantly higher than those in the control group,the differences were statistically significant(P＜0.05).ConclusionThe clinical efficacy of levamlodipine besylate combined with valsartan in the treatment of essential hypertension is significant,which can significantly reduce the clinical symptoms and improve the quality of life of patients.
2017 Vol. 24 (31): 26-28转32 [Abstract] ( 236 ) HTML (33 KB)  PDF  (0 KB)  ( 63 )
29 Research focus analysis of coronary restenosis based on PubMed database
CHEN Kai-ming
ObjectiveTo analyze the current research on coronary restenosis by reviewing the related literature.MethodsBased on PubMed database,the literature on coronary restenosis published from August 2012 to July 2017 was searched and analyzed,and the frequency of subject headings was calculated.Term－paper matrix was in cluster analysis by using SPSS statistical software in order to obtain the research highlight of coronary restenosis.ResultsIn total,1405 papers related to coronary restenosis have been retrieved and 48 high－frequency subject words were obtained with a cumulative percentage of 61.35%.The highest frequency subject word was drug－eluting stents in 542 times.Ten research focus were obtained by the cluster analysis of 48 subject headings.ConclusionResearch focus of coronary restenosis in recent five years are relationship between cardiac catheter and coating material and coronary restenosis,relationship between absorbable internal fixed support and coronary restenosis,medical diagnosis of coronary angiography on coronary restenosis,impact on surgery on coronary restenosis,common drugs of support and coating in clinic on treating coronary restenosis,etiology of optical coherence tomography on coronary restenosis,coronary restenosis caused by PCI,association of blood and coronary restenosis,prevention and treatment of coronary restenosis after PCI in patients with myocardial infarction,and genetic research on coronary restenosis.The above research focus provides a direction for the in－depth research of clinical and basic researchers.
2017 Vol. 24 (31): 29-32 [Abstract] ( 164 ) HTML (31 KB)  PDF  (0 KB)  ( 56 )
33 Influence of hypertension on vascular endothelial function and homocysteine level in patients with acute cerebral infarction
PENG Xiao-yu
ObjectiveTo observe and analyze the influence of hypertension on vascular endothelial function and homocysteine level in patients with acute cerebral infarction.MethodsFrom June 2014 to June 2016,200 patients with acute cerebral infarction in Department of Neurology in our hospital were selected for study.According to whether hypertension was combined or not,they were divided into cerebral infarction with normal blood pressure group(normal group)and cerebral infarction group with hypertension group(combined group),and 100 cases were in each group.At the same time, another group of 100 healthy people for physical examinations were selected as control group.FMD of brachial artery, IMT,and levels of Hcy,NO,and eNOS were retrospectively analyzed and their relationships were comprehensively analyzed.ResultsThe levels of carotid IMT and serum Hcy in the normal group and the combined group were significantly higher than those in the control group (P＜0.05).The levels of FMD,serumNO,andeNOS were greatly lower than those in the control group,the difference was statistically significant(P＜0.05).The levels of carotid IMT and serum Hcy in the combined group were much higher than those in the normal group(P＜0.05).The levels of FMD,serumNO,andeNOS were significantly lower than those in the normal group,the difference was statistically significant(P＜0.05).The Spearman linear correlation analysis showed that there were negative correlations between IMT and serum NO,and between IMT and eNOS level in the normal group and combined group(P＜0.05),but a positive correlation with serum Hcy level(P＜0.05).The FMD was positively correlated with the levels of serum NO and eNOS in the normal group and combined group(P＜0.05),but negatively correlated with serum Hcy level(P＜0.05).Conclusion There are vascular endothelial dysfunction and homocysteinemia in patients with acute cerebral infarction,and both of them have important synergistic relationship with the occurrence and development of acute cerebral infarction together with hypertension.Early ultrasound measurement of IMT and FMD can predict the occurrence of cerebral infarction.
2017 Vol. 24 (31): 33-35转38 [Abstract] ( 188 ) HTML (36 KB)  PDF  (0 KB)  ( 66 )
36 Clinical effect of standard large bone flap decompression in treatment of severe craniocerebral injury
YI Shuang-hong；ZHANG Bei；ZENG Wen-yu
ObjectiveTo investigate and analyze the clinical effect of standard large bone flap decompression in the treatment of severe craniocerebral injury.MethodsFrom November 2015 to November 2016,60 patients with severe craniocerebral injury treated in our hospital were selected,and they were divided into observation group and control group according to different surgical treatment methods,30 cases in each group.The control group was treated with traditional craniotomy,the observation group was treated with standard large bone flap decompression.The intracranial pressure,GCS score and recovery of the two groups were compared at the third,fifth,seventh days after operation.ResultsThe intracranial pressure of the control group was higher than that of the observation group in the third,fifth,seventh days postoperation(P＜0.05),while the score of GCS in the control group was lower than that in the observation group(P＜0.05).The recovery condition in the observation group was better than that in the control group(Z=－3.113,P＜0.05).ConclusionStandard large bone flap decompression is more effective in the treatment of severe traumatic brain injury,can significantly reduce intracranial pressure,reduce mortality and complications.
2017 Vol. 24 (31): 36-38 [Abstract] ( 191 ) HTML (30 KB)  PDF  (0 KB)  ( 44 )
39 Clinical efficacy of neuronavigation-assisted minimally invasive operation and subsequent fibrinolysis using Urokinase on hypertensive basal ganglia hemorrhage
DING Guan-fu； CHEN Jin-min ；WANG Hai-bing；ZENG Zhao-Bin
ObjectiveTo explore the effect of a combination of neuronavigation-assisted minimally invasive operation and Urokinase on the treatment of hypertensive basal ganglia hemorrhage.MethodsA retrospective analysis was performed by including 36 patients with hypertensive basal ganglia hemorrhage that were treated by Urokinase following neuronavigation-assisted minimally invasive operation from January 2015 to January 2017 in our hospital.Surgical results,procedure-related complications and clinical outcomes were evaluated subsequently.ResultsA total of 36 patients were enrolled in the study,2 patients died of respiratory failure(two patients)and 1 patient died of heart disease.In addition,5 patients occurred surgical complications,including 1 case of ectopic drainage,2 cases of rebleeding into a hematoma cavity,1 case of hemorrhage in puncture tract,and 1 case of intracranial pneumatocele.Incorporated patients were followed up for 3 months,22 patients achieved better treatment results (Glasgow outcome scale score＞3 scores).ConclusionNeuronavigation-assisted minimally invasive operation and subsequent fibrinolysis using Urokinase is a simple,safe and effective procedure for the treatment of hypertensive basal ganglia hemorrhage.
2017 Vol. 24 (31): 39-42 [Abstract] ( 186 ) HTML (40 KB)  PDF  (0 KB)  ( 47 )
43 Effect of enteral nutrition support time on prognosis of patients with severe craniocerebral injury
ZHOU Hai；TENG Hong-wei；ZHOU Jing；QIU Jing-song；GAO Feng；YANG Hua；WANG Guo-jun； PU Pu ；YANG Zi-wei
ObjectiveTo investigate the effect of the time of enteral nutrition support on prognosis of patients with severe craniocerebral injury.Methods146 cases of severe craniocerebral injury patients from June 2013 to September 2015 were randomly divided into treatment group(n=74)and control group(n=72).The treatment group was given early enteral nutrition therapy (24－48 h),the control group was given delayed enteral nutrition treatment(6－7 d),The GCS score,nutritional index and nitrogen balance before and after treatment as well as the incidence of complications were observed.ResultsAfter treatment,the Glasgow coma index of the treatment group were better than the control group(P＜0.05).The total protein,albumin,total lymphocyte count,nitrogen balance recovery of patients in the treatment group were better than the control group(P＜0.05).The incidence of respiratory tract infection,gastrointestinal bleeding,gastrointestinal discomfort and hyperglycemia in the treatment group were lower than those in the control group,the difference was statistically significant(P＜0.05).ConclusionEnteral nutrition support within 24－48 h can significantly improve the GCS score,nutritional index and nitrogen balance in patients with severe craniocerebral injury.
2017 Vol. 24 (31): 43-45 [Abstract] ( 159 ) HTML (34 KB)  PDF  (0 KB)  ( 80 )
46 Effects of early combination of occupational therapy on upper limb mobility and quality of life in the patients with acute cerebral infarction
LIU Jie-mei；CHEN Guo-liang ；CAI Qi-fang
ObjectiveTo analyze the effect of early combination of occupational therapy on the upper limb mobility in acute cerebral infarction.Methods57 patients with acute cerebral infarction who were treated in our hospital from May 2015 to December 2016 were selected.According to different intervention methods,the subjects were grouped,with the treatment group of 29 cases,and the control group of 28 cases.Patients of two groups were given physical rehabilitation within 24 hours after stability of vital signs.The treatment group was given combined occupational therapy on this basis. FMA scores and ADL scores were compared between the two groups.ResultsIn terms of FMA (upper limb part)between the two groups,there was no significant difference in FMA score between the treatment group and the control group before treatment(P＞0.05).After 3 weeks of treatment,the FMA scores were increased in both groups(P＜0.05),and the score in the treatment group was higher than that in the control group(P＜0.05).In terms of the daily life and activity,there was no significant difference in ADL score between the treatment group and the control group before the treatment(P＞0.05).fter 3 weeks of rehabilitation training,ADL scores were improved in both groups(P＜0.05),and the score in the treatment group was higher than that in the control group(P＜0.05).ConclusionEarly combination of occupational therapy can effectively improve the mobility of upper limb in patients with acute cerebral infarction,which can be popularized clinically.
2017 Vol. 24 (31): 46-48 [Abstract] ( 184 ) HTML (1 KB)  PDF  (0 KB)  ( 44 )
49 Effect of modified large bone flap craniotomy in severe craniocerebral injury
XIE Cheng-jin ；LIU Guang-pu； LI Jing-song
ObjectiveTo investigate the clinical efficacy and safety of modified large bone flap craniotomy in severe craniocerebral injury.Methods88 severe craniocerebral injury patients from January 2014 to February 2017 in our hospital were selected.Patients were divided into observation group and control group according to number method,and each group was 44 cases.Patients in control group were given general bone flap craniotomy,and patients in observation group were used modified large bone flap craniotomy.The changes of intracranial pressure before and after the operation were compared between the two groups,and the postoperative.Barthel index,Glasgow outcome score(GOS)and postoperative complications were observed.ResultsThere was no significant difference between the two groups in preoperative intracranial pressure(P＞0.05).The postoperative intracranial pressure of the two groups decreased significantly(P＜0.05), but the improvement degree of the observation group was better than that of the control group(P＜0.05).The incidence of postoperative complications in the observation group was 6.8%（3/44）,significantly lower than that in the control group [36.4%(16/44)],the difference was statistically significant(P＜0.05).ConclusionThe treatment of severe craniocerebral injury with modified large bone flap craniotomy can reduce intracranial pressure,reduce complications and improve the prognosis of patients.It is worth popularizing and applying in clinic.
2017 Vol. 24 (31): 49-51 [Abstract] ( 193 ) HTML (33 KB)  PDF  (0 KB)  ( 44 )
52 Influence of modified electroconvulsive therapy on cognitive function in patients with schizophrenia
CHEN Feng； LONG Xiao-hui；CHEN Li-li
ObjectiveTo observe and analyze the influence of modified electroconvulsive therapy(MECT)on cognitive function in patients with schizophrenia.MethodsA total of 70 schizophrenic patients in Department of Psychiatry admitted into our hospital from January 2016 to January 2017 were selected as observation objects.By a random number table,they were evenly divided into control group and experimental group,35 cases in each group.Patients in the control group were treated with a new antipsychotic medicine.Patients in the experimental group were treated with a new antipsychotic combined with MECT.The PANSS and RBANS scores before and after the treatment,trail making test A and B(TMT),and digit symbol test were compared between the two groups before and after treatment.Results The scores of PANSS in the experimental group were all improved and the improvement was better than those in the control group(P＜0.05).There was great difference in RBANS scores,and the difference in the experimental group was superior to that in the control group(P＜0.05).The time to finish TMT－A and－B in the two groups was shorter with fewer errors compared with that before treatment.The improvement in the experimental group was better than that in the control group (P＜0.05).After treatment,the digit symbol test in the experimental group was shorter than that in the control group,and the total score was higher than that in the control group,the difference was statistically significant(P＜0.05).ConclusionThe combination of new antipsychotic drugs and MECT in the treatment of schizophrenic patients can obtain a favorable effect,which is worthy of promotion.
2017 Vol. 24 (31): 52-54 [Abstract] ( 170 ) HTML (34 KB)  PDF  (0 KB)  ( 71 )
55 Analysis of the advantages and disadvantages of minimally invasive hematoma puncture and traditional craniotomy in the treatment of senile cerebral hemorrhage
LI Huan-liang； HOU Xiao-bin
ObjectiveTo explore and analyze the advantages and disadvantages of minimally invasive hematoma puncture and traditional craniotomy in the treatment of senile cerebral hemorrhage.MethodsFrom June 2011 to March 2016,124 senile patients with cerebral hemorrhage treated in our hospital were selected as research objects.According to a random number table,they were evenly divided into the observation group and the control group,62 cases in each group.In the observation group，minimally invasive hematoma puncture for the treatment was selected,while in the control group,traditional craniotomy was applied.The related clinical indicators including intraoperative amount of bleeding, operationtime,intracerebral hematoma clearance,ICU time after surgery,the score of National Institutes of Health Stroke Scale(NIHSS),GOS score,and the score of SF－36 living quality questionnaire were observed and recorded.ResultsThe indicators of intraoperative amount of bleeding,operationtime,ICU time after surgery,hematomaclearance,and SF－36 score in the observation group were all superior to those in the control group with statistical differences(P＜0.05).The NIHSS score and GOS score evaluating good rate and mortality in the observation group were better than those in the control group with statistical differences(P＜0.05).ConclusionCompared with the traditional craniotomy,application of minimally invasive hematoma puncture in the treatment of senile cerebral hemorrhage can obtain a remarkable effect and effectively increase the hematoma clearance at advantages of reducing intraoperative amount of bleeding,shortening operation time，and decreasing patient′s mortality,which can be promoted in clinical practice.
2017 Vol. 24 (31): 55-57 [Abstract] ( 183 ) HTML (36 KB)  PDF  (0 KB)  ( 39 )
58 Comparison of different doses of Ambroxol Hydrochloride Injection in the treatment of stroke-related pneumonia in the elderly
YE Zhang-hai
ObjectiveTo investigate the clinical efficacy of different doses of Ambroxol Hydrochloride in the treatment of stroke－related pneumonia in the elderly.MethodsA total of 90 patients with acute stroke were diagnosed as SAP in our hospital from January 2016 to June 2017.They were randomly divided into low－dose Ambroxol Hydrochloride group (low－dose group 30 cases),high－dose Ammonia Bovine group(high－dose group 30 cases)and control group(30 cases). The control group receivedonly routine antibiotic therapy.Ambroxol Hydrochloride group was supplemented with different doses of Ambroxol Hydrochloride,and the antibiotic use time,fever time,hospitalization time,arterial oxygen partial pressure,C－reactive protein and bacterial clearance rate,analyed of three groups of clinical efficacy.ResultsThe total effective rate of high－dose group and low－dose group was higher than that of control group (P＜0.05),and high－dose group was higher than low－dose group,the difference was statistically significant(P＜0.05).The antibiotic use time,fever time and hospitalization time of the high dose group and low dose group were significantly shorter than those of the control group(P＜0.05),and the high dose group was shorter than that of low dose group,the difference was statistically significant(P＜0.05).The high dose group was higher than that of low dose group(P＜0.05),and the high dose of group and low dose group was higher than that of control group,the difference was statistically significant(P＜0.05).There was no significant difference in C－reactive protein between the three groups(P＞0.05).The bacterial clearance ratein the high－dose group was 90.27%and the low－dose group was 68.51%.The bacterial clearance rate in the control group was 57.80%,and the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of clinical adverse reactions between the three groups(P＞0.05).ConclusionsHigh－dose Ambroxol Hydrochloride in the treatment of stroke－related pneumonia in elderly patients with significant effect,can improve bacterial clearance,and clinical safer, worthy of promotion and application.
2017 Vol. 24 (31): 58-60转64 [Abstract] ( 185 ) HTML (37 KB)  PDF  (0 KB)  ( 71 )
61 Effect comparison of controlled decompression and standard large decompressive craniectomy in the treatment of senile severe craniocerebral injury complicated with cerebral infarction
XU Xin ；CHEN Xiao-ping
ObjectiveTo explore the effect comparison of controlled decompression and standard large decompressive craniectomy in the treatment of severe craniocerebral injury complicated with cerebral infarction in the elderly.MethodsThe clinical data of 72 patients treated in our hospital from January 2010 to October 2016 were analyzed.According to the different surgical methods，they were evenly divided into controlled decompression group and standard large decompressive craniectomy group,36 cases in each group.The conditions of intracranial pressure before,during,just after, and 6－month after surgeries were observed in the two groups.The NCSE score,Barthel index and GOS score of the two groups were observed 6 months after operation.The favorable rate for prognosis in the two groups was also observed.ResultsBefore surgery,there was no significant difference in the intracranial pressure between the two groups.During, just after,and 6－month after operation,the intracranial pressure of the two groups was lower than that in the standard large decompressive craniectomy.In the controlled decompression,the NCSE score,Barthel index,and GOS score were all higher than those in the standard large decompressive craniectomy group 6 months after operation.The favorable rate for prognosis in the controlled decompression group was better than in the that of standard large decompressive craniectomy group,with a statistical difference(P＜0.05).ConclusionControlled decompression is effective in the treatment of severe craniocerebral injury complicated with cerebral infarction in the elderly with remarkable improvement of intracranial pressure and favorable rate for prognosis,which is worthy of clinical application and promotion.
2017 Vol. 24 (31): 61-64 [Abstract] ( 210 ) HTML (35 KB)  PDF  (0 KB)  ( 39 )
65 The clinical effect of ventriculoperitoneal shunt combined with cranioplasty in the treatment of hydrocephalus complicated with skull defect
CHEN Da
ObjectiveTo investigate the clinical effect of ventriculoperitonealV－Pshunt combined with cranioplasty in the treatment of hydrocephalus complicated with skull defect.Methods60 cases of hydrocephalus complicated with skull defect were treated in our hospital from December 2014 to April 2017.The treatment group was divided into the treatment group and the control group,and 30 cases in each group.The patients in the treatment group underwent ventriculoperitoneal shunt combined with cranioplasty,while patients in the control group underwentV－Pshunt and underwent cranioplasty after 2－3 months.The neurological function,body function and complications of the two groups were evaluated.ResultsThe scores of neurological deficits in 15 day and 30 day after treatment were higher in the treatment group than in the control group.The scores of ADL,Fugl－Meyer,GCS and GOS in the treatment group were better than those in the control group.The complication rate of the treatment group (13.3%)was significantly lower than that of the control group (36.7%).The differences were statistically significant(P＜0.05).ConclusionV－Pshunt combined with cranioplasty for hydrocephalus combined with skull defect can reduce postoperative complications and has positive significance for the rehabilitation of patients.
2017 Vol. 24 (31): 65-67 [Abstract] ( 172 ) HTML (33 KB)  PDF  (0 KB)  ( 66 )
68 Correlation study of insulin resistance and carotid intima-media thickness in diabetes mellitus/non-diabetes mellitus patients with peritoneal dialysis
YANG Guang；LI Xiao-yan；PENG Hong-xia
ObjectiveTo explore the correlation between insulin resistance and carotid intima-media thickness in diabetes mellitus(DM)/non-DM patients with peritoneal dialysis.MethodsFrom June 2016 to June 2017,56 end-stage renal disease(CHD)patients with DM/non-DM who were performed with peritoneal dialysis in our hospital were selected. There were 28 cases with DM and the rest were not occurred with DM.According to insulin resistance or not,they were divided into insulin resistance group and non-insulin resistance group.The correlation of insulin resistance and carotid intima-media thickness in the two groups was compared.ResultsFor DM patients,insulin resistance had positive correlations with 2 h PBG,CIMT,LDLC,TG and hs-CRP(P＜0.05).In the non-DM group,insulin resistance was positively correlated with 2 h PBG,CIMT,HbA1c,LDLC,TG and hs-CRP(P＜0.05).ConclusionInsulin resistance in DM/non-DM patients is both positively correlated with 2 h PBG,CIMT,LDLC,TG and hs-CRP,which indicates insulin resistance can promote the thickening of carotid intima-media thickness.
2017 Vol. 24 (31): 68-70转79 [Abstract] ( 192 ) HTML (36 KB)  PDF  (0 KB)  ( 41 )
71 Analysis of Clinical conditions of elderly patients of the first receiving hemodialysis in single center
ZENG Yu-ran ；TAN Feng-jiao ；YAN Li-jun ；LIN Wan-min
ObjectiveTo analyze the clinical conditions of elderly patients who first underwent hemodialysis so as to reflect their characteristics.MethodsThe primary causes,complications and laboratory findings of 185 newly-diagnosed patients who first underwent hemodialysis in our hospital from January 2013 to December 2015 were analyzed.ResultsAmong 185 cases of elderly patients who first underwent hemodialysis,the diabetic nephropathy (54.6%),chronic glomerulonephritis(21.1%)and hypertensive nephropathy(14.6%)ranked the top three primary causes.Severe complications included acute left heart failure,severe acidosis,hyperkalemia,severe anemia,and the incidence rate was 34.6%, 35.7%,19.5%and 20.0%,respectively.Two or more serious complications occurred in more than 30%of the elderly patients with initial hemodialysis.ConclusionThe primary etiology of elderly patients who accepted initial hemodialysis includes diabetic nephropathy,chronic glomerulonephritis and renal hypertension.And the patients with hemodialysis often are associated with high incidence of serious complications.
2017 Vol. 24 (31): 71-73 [Abstract] ( 206 ) HTML (33 KB)  PDF  (0 KB)  ( 45 )
74 Minimally invasive treatment of severe urethral stricture
WU Jun-yan
ObjectiveTo explore the curative effect of minimally invasive in the treatment of severe urethral stricture, and to provide guidance for clinical practice.Methods62 patients with severe urethral stricture who were admitted to our hospital from October 2009 to December 2014 were selected as the study subjects.The clinical data of 62 patients with severe urethral stricture were retrospectively analyzed.26 patients were given traditional surgical treatment(the traditional group),and 36 patients were given minimally invasive surgery (the minimally invasive group).The patients were all followed up for 2 years.The operation time,intraoperative blood loss,clinical efficacy,urinary flow rate,length of stay,incidence rate of complications and recurrence rate were compared between the two groups.ResultsThe operation time,length of stay in the minimally invasive group was shorter than that in the traditional group,the intraoperative blood loss in the minimally invasive group was less than that in the traditional group,with significant difference (P＜0.05).The urine flow rate of the two groups after treatment was significantly higher than before treatment,with significant difference(P＜0.05).There was no significant difference in the urine flow rate between the two groups after treatment(P＞0.05).The cure rate of the minimally invasive group was 97.22%,compared with 92.31%of the traditional group,the difference was not statistically significant(P＞0.05).The incidence rate of complication in the minimally invasive group was 0.00%,which was significantly lower than 15.38%in the traditional group,with significant difference (P＜0.05).The patients were followed-up for 2 years,and no recurrence was seen in the minimally invasive group.Compared with 7.69% in the traditional group,the difference was not statistically significant(P＞0.05).ConclusionThe minimally invasive treatment for the patients with severe urethral stricture has a significant effect,and the operation time is shorter,intraoperative bleeding is less,which can significantly reduce the risk of complications in the patients,promote the prognosis and shorten the length of stay.
2017 Vol. 24 (31): 74-76 [Abstract] ( 170 ) HTML (36 KB)  PDF  (0 KB)  ( 67 )
77 Effect observation of ureteral soft mirror combined with holmium laser in the treatment of renal and upper ureteral calculi
LIU Xue-feng ；SHI Li-jiao ；LI Bing-hua
ObjectiveTo explore the clinical efficacy of ureteral soft mirror combined with holmium laser in the treatment of renal and upper ureteral calculi.Methods90 patients with renal and upper ureteral calculi who were treated in our hospital from July 2015 to February 2017 were selected and randomly divided into the control group and the observation group,with 45 patients in each group.The control group was given extracorporeal shock wave lithotripsy,and the observation group was given ureteral soft mirror combined with holmium laser.The stress index levels,the exclusion rate of stone and the incidence rate of complications were compared between the two groups.ResultsThere were no significant differences in the level of Cor,CRP and IL-6 between the two groups before treatment(P＞0.05).The levels of Cor, CRP and IL-6 in the observation group after treatment were significantly lower than those in the control group after the treatment,with significant difference (P＜0.05).The rate of stone exclusion in the observation group was 97.78%,which was higher than 84.44%in the control group,with significant difference(P＜0.05).The incidence rate of complications in the observation group was 13.33%,which was lower than 42.22%in the control group,with significant difference (P＜0.05).ConclusionUreteral soft mirror combined with holmium laser therapy in the treatment of renal and upper ureteral calculi can effectively improve the overall stone exclusion rate,with less trauma,while the rate of complications can be better controlled,which is worthy of clinical promotion.
2017 Vol. 24 (31): 77-79 [Abstract] ( 187 ) HTML (32 KB)  PDF  (0 KB)  ( 45 )
80 Effect of Leflunomide combined with glucocorticoid in the treatment of advanced IgA nephropathy and its influence on VCAM-1 level
SHI Cai-lin
ObjectiveTo explore the Leflunomide combined with glucocorticoid on treating advanced IgA nephropathy and its influence on VCAM-1 level.MethodsFrom March 2015 to January 2017,108 advanced IgA nephropathy patients treated in our hospital were selected as research objects.According to their different therapeutic time,they were evenly divided into the treatment group and the control group,54 cases in each group.In the treatment group,Leflunomide combined with glucocorticoid was used,while in the control group,Prednisolone was applied.The therapeutic effect, detection indicators like serum,etc.,and adverse reactions after treatment in the two groups were recorded.ResultsAfter treatment,the total effective rate was 92.59%in the treatment group,which was higher than that in the control group (75.98%)(P＜0.05).After treatment,the urine protein content,serumalbumin content,serum creatinine content,glomerular filtration rate,and the level of VCAM-1 all tended to normal values,which were displayed statistical differences compared with before treatment(P＜0.05).There was significant difference in the urine protein content,serumalbumin content,serum creatinine content,glomerular filtration rate,and the level of VCAM-1 between the two groups after treatment(P＜0.05).The total adverse reaction rate in the treatment group was 18.52%,and 24.07%in the control group,there was no significant difference (P＞0.05).ConclusionCombination of Leflunomide and glucocorticoid in the treatment of progressive IgA nephropathy is effective,and it is helpful for the self-recovery of these patients and can greatly decrease VCAM-1 level.It is worthy to be promoted in clinical practice,which has a remarkable medical value and is of great significance.
2017 Vol. 24 (31): 80-82 [Abstract] ( 191 ) HTML (34 KB)  PDF  (0 KB)  ( 71 )
83 Clinical effect of immunosuppressant Cyclophosphamide in the treatment of acute interstitial nephritis
JIN Bi-hui；WANG Cai-hong
ObjectiveTo investigate the clinical effect of immunosuppressant Cyclophosphamide in the treatment of acute interstitial nephritis.Methods30 patients with acute interstitial nephritis who were admitted to our hospital from June 2015 to April 2017 were enrolled as the study subjects.According to the different treatment methods,the patients were divided into the control group and the treatment group,with 15 cases in each group.Patients in the control group were given hormones,and patients in the treatment group were given hormones combined with cyclophosphamide immunosuppressant.Improvement of relevant biochemical indicators(including serum uric acid,blood urea nitrogen,serum creatinine,endogenous creatinine clearance rate),the length of hospital stay,the incidence rate of adverse reactions,the total effective rate of treatment were compared between the two groups.ResultsThere were no significant differences in the relevant biochemical indicators of serum uric acid,blood urea nitrogen,serum creatinine,endogenous creatinine clearance rate between the two groups before treatment(P＞0.05).The level of serum uric acid,blood urea nitrogen,serum creatinine in the treatment group after treatment were significantly lower than those in the control group,the level of serum creatinine clearance rate in the treatment group after treatment was significantly higher than the control group,with significant difference (P＜0.05).The length of hospital stay in the treatment group was significantly shorter than that in the control group,with significant difference (P＜0.05).The incidence rate of adverse reactions in the treatment group was 6.7%,which was significantly less than 13.3%in the control group,with significant difference (P＜0.05).Conclusion The application of Cyclophosphamide immunosuppressant in the treatment of patients with acute interstitial nephritis can effectively improve the biochemical indicators of patients,so as to rapidly promote the recovery of renal function in patients,and the efficacy is safe and reliable.
2017 Vol. 24 (31): 83-85 [Abstract] ( 149 ) HTML (32 KB)  PDF  (0 KB)  ( 36 )
86 Comparisonofeffectivenessofminimally-invasivepercutaneousnephrolithotomy and retroperitoneal laparoscopic ureterolithotomy in the treatment of upper ureteral calculi
CHEN Chuan-cong

ObjectiveTo compare the efficacy of minimally-invasive percutaneous nephrolithotomy(MPCNL)and retroperitoneal laparoscopic ureterolithotomy(RLU)in the treatment of upper ureteral calculi.MethodsAltogether 202 cases of upper ureteral calculi patients who were treated in our hospital from January to December 2015 were retrospectively analyzed and divided into the MPCNL group(121 cases)and the RLU group(81 cases)according to the different treatment methods.The efficacy of the two groups was compared and the statistical analysis of length of operation,the amount of bleeding,length of stay,one-time lithotripsy success rate,repeated treatment rate,the incidence rate of complications and postoperative stone clearance rate was statistically analyzed between the two groups.ResultsThe length of operation and length of stay in the RLU group were shorter than those in the MPCNL group,the amount of bleeding in the RLU group was less than that in the MPCNL group,the one-time lithotripsy success rate and postoperative stone clearance rate in the RLU group were higher than those in the MPCNL group,the repeated treatment rate and the incidence rate of complications in the RLU group were lower than those in the MPCNL group,with statistically significant difference (P＜0.05).ConclusionThe operation time and length of stay of RLU in the treatment of upper ureteral calculi is shorter and the amount of bleeding is less,the curative effect is better than that of MPCNL.
2017 Vol. 24 (31): 86-88 [Abstract] ( 152 ) HTML (33 KB)  PDF  (0 KB)  ( 75 )
89 Application effect of stellate ganglion block in the treatment of cervical spondylotic radiculopathy in outpatient clinic
YUAN Zhi-feng；CHEN Xu-lin ；OUYANG Yu-xuan
ObjectiveTo explore the clinical efficacy of stellate ganglion block in the treatment of cervical spondylotic radiculopathy.Methods90 patients with cervical spondylotic radiculopathy treated in our hospital from April 2015 to April 2016 were selected.According to different therapeutic methods,they were evenly divided into the control group and the observation group,45 cases in each group.In the control group,paravertebral block was used,while in the observation group,stellate ganglion block was adopted.The scores of visual analogue scale (VAS)in time-set points,clinical efficacy,and clinical signs before and after treatment were compared in the two groups.ResultsThe total therapeutic effective rate in the observation group was 97.78%,which was higher than 82.22%in the control group,with a statistical difference (P＜0.05).The VAS scores of the observation group at 10 min,3 d and 7 d after treatment were lower than those of the control group,with significant difference(P＜0.05).After one-week treatment,the scores of neck and shoulder pain and discomfort,numbness and pain in the upper limbs,and brachial plexus traction in the observation group was lower than that in the control group,with significant difference(P＜0.05).ConclusionStellate ganglion block in the treatment of cervical spondylotic radiculopathy can effectively alleviate patient′s symptoms so that they go into daily life and work as soon as possible.Inaddition,the therapeutic regimen is simple to perform,and suitable for wide application and promotion in grass-root hospitals.
2017 Vol. 24 (31): 89-91 [Abstract] ( 161 ) HTML (36 KB)  PDF  (0 KB)  ( 44 )
92 Influence of external fixation and open reduction and internal fixation on the curative effect of unstable distal radius fracture and the wrist function in elderly patients
ZENG Huan-gao ；BI Dian-hai；LIAO Yong； LIAO Shui-sheng
ObjectiveTo investigate the curative effect of combining external fixation and small splint external fixation as well as open reduction and internal fixation in elderly patients with unstable distal radius fractures,and to observe the effect of each program on the wrist function.Methods80 elderly patients who came to our hospital for operative treatment for unstable distal radius fracture from November 2014 to November 2016 were selected and randomly divided into the control group and the observation group,40 cases in each group.The control group was treated with plate internal fixation,the observation group was treated with external fixation combined with small splint external fixation.The clinical effects of the two groups was compared.ResultsThe operation time in the observation group was shorter than that in the control group,and intraoperative blood loss in the observation group was less than that in the control group, with significant difference(P＜0.05).There was no significant difference in the time of fracture healing between the two groups(P＞0.05).The angle of palmar inclination and ulnar deviation of the two groups at 3 and 6 months after treatment were better than those before treatment,with significant difference (P＜0.05).There was no significant difference in the angle of palmar inclination and ulnar deviation of the two groups at 3 and 6 months after treatment(P＞0.05).The total excellent and good rate of the control group after 3 months treatment was 97.50%,which was higher than 77.50%of the observation group,with significant difference (P＜0.05).After treatment for 6 months,the total excellent and good rate of the observation group was 92.50%,compared with 100.00%of the control group,the difference was not statistically significant(P＞0.05).ConclusionFor the elderly patients with unstable distal radius fractures,the effect of combination of external fixation and small splint external fixation as well as open reduction and internal fixation are both significant, which can effectively improve the wrist function of the patients,the early recovery of the wrist function is better for the latter,but the former has smaller trauma and higher security,which is available for promotion among patients with low requirements for the recovery of wrist function.
2017 Vol. 24 (31): 92-94转97 [Abstract] ( 141 ) HTML (36 KB)  PDF  (0 KB)  ( 41 )
95 Application of steel plate screw as an internal fixation in the treatment of traumatic fracture of limb tubular bones
HE Yong-qiang ；ZHOU Quan-kun ；DONG Zhang-qing ；TU Jian-long
ObjectiveTo explore the application value of internal fixation of steel plate screw in the treatment of traumatic fracture of limb tubular bones.MethodsA total of 128 patients with traumatic fracture of limb tubular bones from May 2015 to January 2017 in our hospital were selected.According to the odd/even admission sequence,they were evenly divided into the control group and the observation group,64 cases in each group.The control group was treated with internal fixation of closed reduction interlocking intramedullary nail,the observation group was treated with internal fixation of steel plate screw.The curative effect was compared between the two groups.ResultsThe excellent and good rate of fracture healing in the observation group was 93.8%,which was higher than 71.9%in the control group,with significant difference(P＜0.05).The operation time,hospitalization time and fracture healing time of the observation group were significantly shorter than those of the control group,with significant difference (P＜0.05).The incidence rate of adverse reactions in the observation group was 4.7%,which was lower than 15.6%in the control group,with significant difference (P＜0.05).ConclusionThe application of steel plate screw as an internal fixation in the treatment of fractures of limb tubular bones can obtain a remarkable effect.It can facilitate the early healing of fractures in high safety and have a high clinical value for promotion.
2017 Vol. 24 (31): 95-97 [Abstract] ( 155 ) HTML (32 KB)  PDF  (0 KB)  ( 35 )
98 Changes of the level of serum Leptin,TNF-α and IL-6 and its clinical significance in the aged patients with femoral neck fracture before and after total hip replacement
LI Liang-qi；ZHAO Chong-hai；WANG Hai-tao ；CHAI Guo-lu
ObjectiveTo study the level changes of serum Leptin,TNF-α and IL-6 and its clinical significance in the aged patients with femoral neck fracture before and after total hip replacement.Methods56 cases of aged patients with femoral neck fracture who were treated by operation in Jiamusi Orthopaedy Hospital from January 2015 to June 2016 were selected as the observation group,at the same period,50 normal aged individuals were selected as the control group.The serum levels of Leptin,TNF-α and IL-6 were measured in the control group and in the observation group before operation and at the 1st,3nd,7th,14th d after total hip replacement.ResultsThe serum levels of Leptin,TNF-α and IL-6 were significantly higher in aged patients with femoral neck fracture than that the normal aged individuals,the differences were statistically significant(P＜0.01).The serum levels of Leptin,TNF-α and IL-6 were increased grandually at the 1st,3nd,7th d after total hip replacement in the aged patients with femoral neck fracture,the differences were statistically significant(P＜0.01).ConclusionThe high levels of Leptin,TNF-α and IL-6 may involve the development of acute traumatic inflammatory response,which can effect the bone healing.
2017 Vol. 24 (31): 98-100 [Abstract] ( 154 ) HTML (33 KB)  PDF  (0 KB)  ( 46 )
101 Curative effect observation of different dose Progynova applied in for endometrial repair after intrauterine adhesion operation
ZHONG Li-zhen；AI dan
ObjectiveTo observe the curative effect of different dose Progynova applied in for endometrial repair after intrauterine adhesion operation.Methods174 patients with endometrial repair after intrauterine adhesion treated in our hospital from October 12,2015 to March 20,2016 were selected.The patients were divided into the three groups,and there were 58 cases in each group.2 mg group was given 2 mg Progynova for treatment,4 mg group was given 4 mg Progynova for treatment,and 6 mg was given 6 mg Progynova for treatment.The hospital stay,symptom improvement time, hospitalization cost,and incidence of adverse reactions were compared among the three groups.ResultsThe hospital stay, symptom improvement time,and hospitalization cost after therapy in 4 mg group was(15.01±0.45)d,(8.45±1.29)d,(3565.11± 127.48)yuan respectively,which were better than those in 2 mg group [(21.25±1.47)d,(10.28±2.11)d,and (5627.49± 159.28)yuan],and 6 mg group[(18.45±1.25)d,(9.24±0.28)d,(4252.45±145.11)yuan](P＜0.05).The incidence of adverse reactions in 4 mg group was 6.90%,which was lower than that of the 2 mg group (20.90%)and the 6 mg group (12.07%)(P＜0.05).ConclusionFor endometrial repair patients after intrauterine adhesion,application of 4 mg Progynova can obtain a remarkable effect.
2017 Vol. 24 (31): 101-102转118 [Abstract] ( 157 ) HTML (30 KB)  PDF  (0 KB)  ( 43 )
103 Study on the reference value of thyroid function in middle and late pregnancy in our hospital
HE Jie ；WANG Xiao-jiao
ObjectiveTo analyze the range of reference value of serum thyroid function in middle and late pregnancy.Methods500 cases of pregnant women who
receivedpregnancy check in our hospital from February 2016 to February 2017 were enrolled as the study group,among them,it included 300 cases of middle pregnancy women and 200 cases of late pregnancy women.Another 200 cases of healthy non－pregnant women of childbearing age were enrolled as the control group.The serum level of free thyroxine (FT4),thyroid stimulating hormone (TSH),thyrotropin receptor antibody (TRAb),anti－thyroglobulin antibody(TgAb)and anti－thyroid peroxidase antibody(TPOAb)of the subjects were detected by chemiluminescence immunoassay,the reference value of FT4and TSH in middle and late pregnancy were initially tested by methods which recommended by American Institute of Clinical Biochemistry(NACB).ResultsThe distribution situation of serum FT4was ranged from 9.79 to 17.29 pmol/L and 9.53 to 16.85 pmol/L in middle and late pregnancy respectively.The distribution situation of serum TSH was ranged from 0.64 to 5.33 mIU/L and 0.61 to 5.62 mIU/L in middle and late pregnancy respectively.The incidence rate of thyroid disease was 7.2%(36/500)when the above reference was used as the judgment criterion.ConclusionEstablishing the normal range of serum thyroid hormone level in different stages of pregnancy can provide a scientific basis for the diagnosis and treatment of thyroid disease during pregnancy.
2017 Vol. 24 (31): 103-105 [Abstract] ( 142 ) HTML (36 KB)  PDF  (0 KB)  ( 41 )
106 Clinical evaluation of procalcitonin determination in children with sepsis
QIN Chao-qiang ；DING Yong-xing ；CHEN Juan
ObjectiveTo explore the clinical sinificance of procalcitonin (PCT)for diagnosis and prognosis of children with sepsis.Methods100 infected children treated in department of pediatrics in our hospital from February 2014 to February 2016 were selected.They were divided into the severe sepsis group (17 cases),non severe sepsis group(23 cases),and non－sepsis group (60 cases)according to the diagnosis criteria.PCT,CRP,WBC were determined and pediatric critical illness score (PICS)was conducted in all cases within 24 hour after admission.ResultsThere was a satatistical difference in PICS,PCT,CRP,WBC among the three groups (P＜0.01).The level of PCT,CRP,WBC in the severe sepsis group and non severe sepsis group were higher than those in the non－sepsis group(P＜0.01).There was no statistical difference of CRP,PCT level between the severe sepsis group and non severe sepsis group(P＞0.05).ConclusionIn the diagnosis of sepsis,PCT is better than CRP and WBC,and it is a sensitive serological indicator.The higher the level of PCT,the lower the PICS.
2017 Vol. 24 (31): 106-108 [Abstract] ( 173 ) HTML (34 KB)  PDF  (0 KB)  ( 31 )
109 Effect of Methylprednisolone combined with conventional treatment on severe hand foot mouth disease in children and its influence on inflammatory factors
LIU Su-hua ；CHEN Xiang-sheng
ObjectiveTo investigate the curative effect of Methylprednisolone combined with conventional treatment on severe hand foot mouth disease (HFMD)in children and its influence on inflammatory factors such as tumor necrosis factor－α(TNF－α),interleukin 1β(IL－1β).Methods90 children with severe hand foot mouth disease from July 2014 to February 2017 treated in our hospital were selected and were divided according to the random number table method, and there were 45 cases in each group.The control group was given the conventional treatment,while the observation group was combined with Methylprednisolone.7 days was a course of treatment.The improvement of inflammatory factors and clinical efficacy were compared between the two groups.ResultsThe oral ulcer healing time,fever disappearing time,appetite improvement time and rash extinction time of the observation group were shorter than those of the control group,and the difference was significant(P＜0.05).After 7 days treatment,serum tumor necrosis factor(TNF－α),interleukin 1β (IL－1β)in two groups were decreased,the difference was statistically significant(P＜0.05).After treatment, TNF－α and IL－1β in observation group was(142.49±25.46)ng/L and(52.92±8.26)ng/ml respectively,which was lower that of the control group[(173.65±27.89)ng/L,(69.85±17.31)ng/ml]respectively,and the difference was significant(P＜0.05).The total effective rate in the observation group was 93.33%,which was higher than that of the control group (77.78%)(P＜0.05).ConclusionMethylprednisolone combined with conventional treatment treating severe hand foot mouth disease in children with has a remarkable effect,which can shorten the course of disease,improve inflammatory response,and promote disease recovery,and it is worthy of promotion.
2017 Vol. 24 (31): 109-111 [Abstract] ( 187 ) HTML (34 KB)  PDF  (0 KB)  ( 38 )
112 Comparison of clinical efficacy and safety of transanal modified Soave and transabdominal surgery treating Hirschsprung disease
GUO Qiu-peng ； HU Zuo-zhen ； HE Xun ； WU Yue ； LI Jun-jie ；WANG Yong
Objective To compare the clinical effect and safety of transanal modified Soave and transabdominal surgery treating Hirschsprung disease.Methods 100 children with Hirschsprung disease treated in our hospital from January 2014 to June 2017 were selected and they were randomly divided into the control group(50 cases)and the observation group (50 cases),and abdominal surgery and transanal modified Soave was performed respectively.The operation time,gastrointestinal function recovery time,hospitalization time,defecation function and incidence of complications were compared between the two groups.Results The operation time,the recovery time of gastrointestinal function and hospitalization time in the observation group were significantly shorter than those in the control group (P＜0.05).The proportion of fully autonomous stool in the observation group was significantly higher than that in the control group,and the proportion of fecal manure was lower than that of the control group,the difference was statistically significant(P＜0.05).The incidence of complications of the observation group was 6.0%,which was significantly lower than that of the control group(28.0%) (P＜0.05).Conclusion Transanal modified Soave is more effective and safe in the treatment of congenital giant colon.It can be used as the first choice for congenital giant colon.
2017 Vol. 24 (31): 112-114 [Abstract] ( 161 ) HTML (33 KB)  PDF  (0 KB)  ( 46 )
115 Retrospective analysis of 104 cases of community-acquired urinary tract infection in children
YUAN Bao-li；DENG Su-juan； XIONG Wei
ObjectiveTo investigate the clinical characteristics of community－acquired urinary tract infection in children so as to improve the early diagnosis rate.MethodsThe clinical characteristics,auxiliary examinations and pathogenic bacteria distribution of 104 children with community－acquired urinary tract infection hospitalized in our hospital from January 2012 to December 2016 were analyzed retrospectively.ResultsThe clinical manifestations of 104 cases were atypical.The main manifestation of children＜2 years old was fever,urine cultures were mainly G－bacilli,especially Escherichia coli(82 cases,78.8%).Some coccus could also cause urinary tract infections,but it only had a small number.The treatment with three－generation cephalosporin antibiotics showed good response to urinary tract infection. Excretory ureter radiography showed the existence of vesicoureteric reflux in partial recurrent urinary tract infection.ConclusionThe community－acquired urinary tract infection in children is uneasy to be early diagnosed.Early routine urinalysis is recommended for patients aged＜2 years with fever as the single manifestation.
2017 Vol. 24 (31): 115-118 [Abstract] ( 185 ) HTML (39 KB)  PDF  (0 KB)  ( 43 )
119 Analysis of speech abnormality and correction effect in children with functional articulation disorder
WANG Yan-song； CHEN Xiao-xia ；LIU Jian-lin
ObjectiveTo observe the speech abnormality and correction effect in children with functional articulation disorder.Methods100 children with functional articulation disorder diagnosed in our hospital from September 21,2014 to September 21,2016 were selected as the research objects.The children were divided into the control group and experimental group using the number table method,and there were 50 cases in each group.The children in the control group were given a single correction treatment,and the experimental group receivedcomprehensive correction treatment. The correction effect of speech,functional articulation disorder degree,and formant of vowel sounds before and after treatment in patients between the two groups were compared.ResultsAfter treatment,the total effective rate in the experimental group was higher than that of the control group,and the difference was statistically significant(P＜0.05).There was a statistical difference of functional articulation disorder degree between the two groups(P＜0.05).Formant of vowel sounds were improved in patients of the two groups compared with before treatment,and the experimental group was better than that of the degree of improvement in the control group,and the difference was statistically significant(P＜0.05).ConclusionFor children with functional articulation disorder,comprehensive correction should be strengthened, which can effectively improve articulation disorder of ill children and be worthy of popularization and application.
2017 Vol. 24 (31): 119-121 [Abstract] ( 148 ) HTML (34 KB)  PDF  (0 KB)  ( 42 )
122 Application of color ultrasonography-guided umbilical vein catheter localization and retention in neonatal umbilical vein catheterization
LIU Zi-zhong ；HUANG Guo-ping； XU Long
ObjectiveTo study the application effect of color ultrasonography－guided umbilical vein catheter localization and retention in umbilical vein catheterization (UVC)in neonates.MethodsFrom April 2013 to March 2016,98 neonates who were in need of UVC and were admitted into our hospital were selected.They were divided into the study group and control group according to the random number table method,and there were 49 cases in each group.Patients in the control group were given routine UVC catheterization,and patients in the study group were given UVC catheterization under the guidance of color ultrasonography.At the end of the treatment,the level of C－reactive protein(CRP), procalcitonin (PCT),serum interleukin－6 (IL－6)and IL－8 content,the occurrence of complications,the success rate of one－time catheterization and retention time of catheterization were compared between the two groups.ResultsThe level of CRP,PCT,IL－6 and IL－8 in the study group were significantly lower than those in the control group(P＜0.05).The total incidence rate of complications in the study group was significantly lower than that in the control group (P＜0.05). The the success rate of one－time catheterization in the study group was significantly higher than that of the control group,and the retention time of catheterization in the study group was significantly longer than that in the control group (P＜0.05).ConclusionThe effect of of color ultrasonography－guided umbilical vein catheter localization and retention in the neonatal UVC is more ideal,and the incidence rate of complications is lower,and the success rate of one－time catheterization is high and retention time of catheterization is longer.
2017 Vol. 24 (31): 122-124 [Abstract] ( 155 ) HTML (36 KB)  PDF  (0 KB)  ( 44 )
125 Value of enhanced CT magnetic resonance scan in the diagnosis of peripheral lung tumors
ZHOU Jian； HU Shao-bo ；LI Zi-cong
ObjectiveTo explore the value of enhanced CT co－magnetic resonance imaging(MRI)in the diagnosis of peripheral pulmonary masses.MethodsThe clinical data of 100 patients with suspected peripheral lung lumps from January 2014 to January 2016 in our hospital were analyzed statistically.All subjects were treated with enhanced CT, MRI and combined examination,The clinical and diagnostic conditions of the three methods were compared and analyzed,and the specificity and sensitivity of the three methods were evaluated and analyzed.ResultsThe specificity and sensitivity of the combined examination were higher(P＜0.05),compared with single CT and MRI.There was no significant difference in CT and MRI findings(P＞0.05).ConclusionEnhanced CT cochlear MRI scans are of high accuracy in the diagnosis of peripheral pulmonary masses,so the clinical application value is higher.
2017 Vol. 24 (31): 125-127 [Abstract] ( 148 ) HTML (32 KB)  PDF  (0 KB)  ( 27 )
128 Imaging analysis of focal nodular hyperplasia MRI and Gd-EOB-DTPA enhanced scanning
HUANG Hui-zhen； ZHAO Ying-jie；HONG Tian-you
ObjectiveTo analyze the typical and atypical imaging features of hepatic focal nodular hyperplasia by MRI plain scan and Gd-EOB-DTPA enhanced scan.MethodsFrom July 2012 to December 2016,the imaging data of 12 patients(15 lesions)with focal nodular hyperplasia of MRI plain scan and Gd-EOB-DTPA enhanced scanning were retrospectively analyzed.Results①MRI plain scan showed that 15 lesions were mainly low signal in T1WI,while the DWI and T2WI-FS were mainly high signal.In addition,MRI scan found that 7 lesions showed central scar,of which T1WI were low signal,but T2WI showed 6 high signals and 1 low signals,DWI showed high signal.②MRI enhanced scan showed that 14 lesions in the arterial phase with obvious uniform strengthening,but the lesion of portal and delayed phases showed slightly higher signals.The central scar of arterial period was not significantly enhanced,while there were 6 lesions with delayed enhancement of scar in the portal and delayed periods.The focal nodular hyperplasia of hepatobiliary phase has a variety of enhanced form,and the central scar were low signal.ConclusionMRI scan and Gd-EOBDTPA enhancement scan can clearly show the internal structure and signal characteristics of the focal nodular hyperplasia.Therefore,mastering the typical and atypical MRI imaging features of focal nodular hyperplasia is helpful to the differential diagnosis of clinical diseases,avoiding unnecessary pathological biopsy or operation,and relieving the pain of patients.
2017 Vol. 24 (31): 128-130转133 [Abstract] ( 205 ) HTML (38 KB)  PDF  (0 KB)  ( 39 )
131 Clinical application value of new ultrasound technology in the cardiac synchronous detection in patients with chronic heart failure
LI Bin；HUANG Ying；LIU Lan
ObjectiveTo explore the clinical application value of new ultrasound technology in the cardiac synchronous detection in patients with chronic heart failure (CHF).MethodsFrom January 2015 to October 2016,25 CHF patients with narrow QRS wave were selected into observation group 1.Meanwhile,another group of CHF patients with wide QRS wave were chosen as observation group 2.In addition,25 healthy volunteers for physical examinations during the same period were recruited into control group.The Ts－6D－12,SPWMD,Tm sv 16－SD%,and ultrasonic indicators before and after surgery were compared among three groups.ResultsIn the observation group 2,the Ts－6D－12,SPWMD,Tm sv 16－SD%were(131.31±12.17)ms,(154.97±5.97)ms,(12.64±4.97)%,which were all higher than the control group(P＜0.05). The outcomes of these indicators were not statistically different from those in the observation group 1.The LVEDD, LVEF,Ts－SD－12,SPWMD,and Tm SV 16－SD in CHF patients in the two groups were all superior to those before treatment with statistical significances(P＜0.05).ConclusionThe clinical application value of new ultrasound technology in the cardiac synchronous detection in CHF is remarkable,and is worthy to be popularized in clinical practice.
2017 Vol. 24 (31): 131-133 [Abstract] ( 175 ) HTML (31 KB)  PDF  (0 KB)  ( 43 )
134 Study on the clinical efficacy and quality of life of Baofukang Suppository combined with Estrogen Ointment for the treatment of vaginitis with diabetes mellitus in elderly patients
WANG Yan； HUANG Xue-ying；TANG Jian-hua
ObjectiveTo investigate and oberseve the curative efficacy and quality of life of Baofukang Suppository combined with Estrogen Ointment for the treatment of vaginitis with diabetes mellitus in elderly patients.Methods88 cases of elderly patients who were treated for vaginitis with diabetes mellitus in our hospital from December 2014 to December 2016 were selected as the research subjects and were divided into the control group and the experimental group, each group had 44 cases.The experimental group were treated with Estrogen Ointment combined with Baofukang Suppository,and the control group was treated by Estrogen Ointment.The clinical efficacy and quality of life of the two groups were compared.ResultsThe clinical efficiency of the experimental group was significantly higher than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,the total quality of life score of experimental group was significantly higher than that of the control group,and the difference was statistically significant (P＜0.05).The adverse reactions in the two groups were compared,and the difference was not statistically significant(P＞0.05).ConclusionThe clinical efficacy of Baofukang Suppository combined with Estrogen Ointment for the treatment of vaginitis with diabetes mellitus in elderly patients is significant,and the quality life is improved significantly,the adverse reaction is less.It is worthy of clinical application.
2017 Vol. 24 (31): 134-136 [Abstract] ( 188 ) HTML (33 KB)  PDF  (0 KB)  ( 45 )
137 Curative effect of low dose Metoprolol in the treatment of severe heart failure
YANG Qiang-feng；LIANG Ya-ling；LI Xiao-qian；WU Yi-yuan
ObjectiveTo investigate the clinical effect of low dose Metoprolol in the treatment of severe heart failure.Methods75 cases of patients with severe heart failure treated in our hospital from January 2015 to June 2016 were selected as the research objects and were randomly divided into the observation group (n=38)and the control group (n= 37).Patients in the control group were given routine treatment while patients in the observation group were treated with small dose of Metoprolol based on the treatment in the control group.And the clinical effect was compared between the two groups.ResultsAfter treatment,the total effective rate of the observation group was 97.37%,which was significantly higher than that of the control group (81.08%),and the difference was statistical significant(P＜0.05).The heart rate of the patients in the observation group was [(67.1±10.3)beats per min],which was lower than that of the control group [(75±12.5)beats per min],and the difference was statistical significant(P＜0.05).The diastolic pressure of the observation group after treatment was[(69.8±5.8)mmHg],which was lower than that of the control group[(76.1±8.0)mmHg],and the difference was statistical significant(P＜0.05).The observation group′s LVD was[(55.3±6.6)mm],LVS was[(36.1±7.3)mm] in the observation group were lower than those of the control group [(62.9±8.5)mm,(42.0±8.1)mm],and LVEF [(57.1± 6.1)%]in the observation group were higher than that of the control group[(51.9±5.5)%],and the differences were statistical significant(P＜0.05).The quality of life score in the observation group was [(86.3±3.7)points],which was higher than that of the control group [(72.2±5.1)points],and the difference was statistical significant(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion Low dose Metoprolol is effective in the treatment of severe heart failure and deserves to be popularized in clinic.
2017 Vol. 24 (31): 137-139转142 [Abstract] ( 182 ) HTML (39 KB)  PDF  (0 KB)  ( 34 )
140 Clinical effect of low-dose Mifepristone in the treatment of adenomyosis
LIU Yu-hong
ObjectiveTo investigate the clinical effect of low－dose Mifepristone in the treatment of adenomyosis.MethodsFrom April 2015 to May 2016,87 adenomyosis patients treated in our hospital were selected as research objects.By an odd and even numbers method,all participants were divided into two groups,control group (n=43)and observation group (n=44).In the control group,large－dose Mifepristone (double dose compared with the observation group),while in the observation group,low－dose Mifepristone was adopted.The clinical therapeutic effect in the two groups was observed.ResultsAfter treatment,the patients in the observation group had more menstrual flow than the control group.The incidence of adverse drug reactions was significantly lower than that in the control group,and the differences were statistically significant(P＜0.05).ConclusionFor adenomyosis patients,application of Mifepristone in different doses both can obtain favorable effects,but more remarkable in a low dose,which effectively improves the menstrual amount and reduces the occurrence of adverse reactions in higher safety.It is worthy of clinical application and promotion.
2017 Vol. 24 (31): 140-142 [Abstract] ( 160 ) HTML (31 KB)  PDF  (0 KB)  ( 97 )
143 Effect observation of Shugan Jieyu Capsules combined with Western Medicine on treating patients with functional dyspepsia accompanied with anxiety and depression
LIU Hong-xin
ObjectiveTo study the clinical effect of Shugan Jieyu Capsules combined with Western medicine in the treatment of patients with functional dyspepsia accompanied with anxiety and depression.MethodsFrom September 2014 to January 2017,96 functional dyspepsia patients with anxiety and depression treated in the outpatient of our hospital were selected as subjects.According to the odd or even sequence of visiting hospital,they were evenly divided into control group(n=48)and observation group(n=48)in random.In the control group,Western medicine was used,while in the observation group,on the basis of the control group,Shugan Jieyu Capsules was combined.The clinical effect,scores of anxiety and depression and incidence of adverse reactions were compared.ResultsIn the observation group,the total clinical efficacy was 95.83%,which was much higher than that in the control group (83.33%),and the difference was statistically significant(P＜0.05).After therapy,the scores of SAS and SDS were lower than before therapy,the scores of SAS and SDS in the observation group were lower than the control group,and the differences were statistically significant(P＜0.05).The adverse reaction rates were compared between the two groups,and the difference was not statistically significant(P＞0.05).ConclusionShugan Jieyu Capsules combined with Western medicine in the treatment of patients with functional dyspepsia accompanied with anxiety and depression can obtain a remarkable effect,which is worthy of clinical promotion.
2017 Vol. 24 (31): 143-145 [Abstract] ( 222 ) HTML (34 KB)  PDF  (0 KB)  ( 76 )
146 Effect observation of Lifukang Lotion combined with Clotrimazole Suppositories for the treatment of mycotic vaginitis in pregnancy
HUANG Li-mei；WANG Hai-xia ；XIA Jian-mei
ObjectiveTo explore the effect of Lifukang Lotion combined with Clotrimazole Suppositories for the treatment of mycotic vaginitis in pregnancy.Methods50 mycotic vaginitis patients in pregnancy treated in our hospital from December 2016 to July 2017 were selected as objects and were divided into control group(20 cases,treated with Baofukang Gel)and observation group (30 cases,Lifukang Lotion combined with Clotrimazole Suppositories)according to different treatment methods.The clinical symptom improvement time and the total effective rate were observed between two groups.ResultsThe vulvovaginal itching and pain disappeared time,vaginal discharge decreased or disappeared time, vaginal congestion and erosion disappeared time in observation group were shorter than those in control group,and the difference was significant(P＜0.05).The total effective rate in observation group was higher than that in control group, and the difference was significant(P＜0.05).ConclusionLifukang Lotion combined with Clotrimazole Suppositories for the treatment of mycotic vaginitis in pregnancy with good clinical effects,which is worth to use.
2017 Vol. 24 (31): 146-148 [Abstract] ( 171 ) HTML (31 KB)  PDF  (0 KB)  ( 41 )
149 Influence study of Ulinastatin as an adjuvant therapy on inflammatory response and organ function in patients with sepsis in intensive care unit
ZHOU Yun-feng
ObjectiveTo investigate the influence of Ulinastatin as an adjuvant therapy on inflammatory response and organ function in patients with sepsis in intensive care unit(ICU).MethodsFrom March 2014 to March 2017,124 patients with sepsis in ICU were selected as subjects.According to a random number table method,they were evenly divided into control group and experimental group,62 cases in each group.In the control group,routine treatment was used, while in the experimental group,on the basis of the control group,Ulinastatin as an adjuvant therapy was added.The content of serum inflammatory cytokines before and after treatment and the indicators of heart,liver,and kidney functions in the two groups were compared.ResultsBefore treatment,the levels of TNF－α,IL－6,hs－CRP,ALT,AST,Cr,BUN, LDH,and CK were compared between the two groups,and the differences were not statistically significant(P＞0.05).After therapy,the levels of TNF－α,IL－6,hs－CRP,ALT,AST,Cr,BUN,LDH,and CK in the experimental group were lower than those in the control group,and the differences were statistically significant(P＜0.05).ConclusionApplication of Ulinastatin in the adjuvant treatment of sepsis patients in ICU can significantly improve the level of inflammatory response and reduce the damage of important organs,which is worthy to be widely promoted.
2017 Vol. 24 (31): 149-151 [Abstract] ( 175 ) HTML (31 KB)  PDF  (0 KB)  ( 49 )
152 Effect evaluation of Cisplatin,Pemetrexed and Recombinant Human Endostatin Injection in the treatment of advanced lung adenocarcinoma
CONG Yun-yan ；LYU Wei-ze ；LIN Zhong
ObjectiveTo investigate the effects of Cisplatin and Pemetrexed,Recombinant Human Endostatin Injection combined with chemotherapy in the treatment of advanced lung adenocarcinoma.MethodsFrom June 2013 to June 2016,62 patients with advanced lung adenocarcinoma treated in our hospital were selected as objects,and the clinical data was analyzed.30 patients who treated with Cisplatin and Pemetrexed was the control group,32 patients who treated with Cisplatin and Pemetrexed and Recombinant Human Endostatin Injection was the observation group.The treatment effects and adverse reactions were compared between the two groups.ResultsThe disease control rate in the observation group(87.50%)was higher than that in the control group(63.33%),and the difference was statistically significant(P＜0.05).The median tumor progression time in the observation group (8 months)was longer than that in the control group (5.5 months),and the difference was statistically significant(P＜0.05).The life quality increases efficiency were compared between the two groups,and the difference was not statistically significant(P＞0.05).The adverse reaction rate were compared between the two groups,and the difference was not statistically significant(P＞0.05).ConclusionThe treatment of Cisplatin and Pemetrexed and Recombinant Human Endostatin Injection combined application in advanced lung adenocarcinoma,the median time to progression of the tumor was significantly prolonged,and will not increase the adverse reactions of patients.It is an effective treatment,worthy of clinical application.
2017 Vol. 24 (31): 152-154 [Abstract] ( 182 ) HTML (34 KB)  PDF  (0 KB)  ( 43 )
155 Clinical effectof Jianpi Qufeng Decoction in the treatment of atopic dermatitis
LI Dong-xiang
ObjectiveTo explore the clinical effect of Jianpi Qufeng Decoction in the treatment of atopic dermatitis.MethodsFrom October 2010 October 2013,160 patients with atopic dermatitis treated in our hospital were selected as the research object,and the patients were divided into the control group and the observation group by taking the computer random number table method,each group had 80 cases.The control group was treated with Prednisone of western medicine,while the observation group was treated with Jianpi Qufeng Decoction.The clinical efficacy,skin itching score, skin lesion score,life quality score of skin disease,incidence of adverse reaction and recurrence rate were compared between the two groups.ResultsThe total effective rate in the observation group was 80.00%,while the total effective rate in the control group was 76.25%,and there was no statistical difference between the two groups(P＞0.05).After 4 weeks treatment,the skin itch score and skin lesion score in the observation group were significantly lower than those of the control group(P＜0.05),and the score of life quality was higher than the control group(P＜0.05).The incidence of adverse reactions in the observation group was 3.75%,which was significantly lower than that of the control group(13.75%)(P＜0.05).The recurrence rate in the observation group was 10.96%,while the control group was 26.09%,and the observation group was lower than that of the control group (P＜0.05).ConclusionUsing Jianpi Qufeng decoction in the treatment of atopic dermatitis,the clinical curative effect is remarkable,and it can effectively relieve skin itching symptoms,improve the quality of life,and it has high safety,less adverse reactions and recurrence.
2017 Vol. 24 (31): 155-157 [Abstract] ( 170 ) HTML (35 KB)  PDF  (0 KB)  ( 68 )
158 Impact of Chinese herbal steaming and washing as an adjuvant therapy of rehabilitation training on functional recovery of knee joint
ZHANG Guo-qing；XU Feng
ObjectiveTo explore the impact of herbal steaming and washing as an adjuvant therapy of rehabilitation training on the recovery of knee joint function.MethodsFrom May 2015 to April 2017,120 patients with knee joint diseases and peripheral fracture were divided into treatment group (n=60)and control group (n=60)based on the sequences of visiting doctors.In the control group,patients were treated with the corresponding rehabilitation training after surgery.In the treatment group,Chinese herbal steaming and washing was added as an adjuvant therapy of rehabilitation training after surgery.The clinical effect,HSS knee score,Lysholm score of knee joint,range of motion (ROM angle)for joint were observed in the two groups.ResultsThe total effective rate was 100%after therapy in the treatment group, which was significantly higher than that in the control group accounting for 80.00% (P＜0.05).After therapy,score of HSS,and Lysholm were all much higher than those in the control group,ROM angle was obviously larger than that of the control group (P＜0.05).ConclusionThe application of herbal steaming and washing assisting on rehabilitation training to patients with knee joint diseases and peripheral fractures can improve the clinical curative effect as well as the function of knee joint,which has a high application value.
2017 Vol. 24 (31): 158-160 [Abstract] ( 159 ) HTML (33 KB)  PDF  (0 KB)  ( 35 )
161 Clinical observation of external application of homemade Jinhuang Ointment in the treatment of anal edema after operation of mixed hemorrhoids
ZHANG Quan-hui；DENG Yong-wen
ObjectiveTo investigate the clinical effect of external application of Homemade Jinhuang Ointment in the treatment of anal edema after operation of mixed hemorrhoids.MethodsFrom September 2014 to February 2017,80 cases suffering from incarcerated mixed hemorrhoids performed with Milligan－Morgan in our hospital were recruited and evenly divided into the control group(external application of Mayinglong hemorrhoid cream only)and observation group (addition of external application of homemade Jinhuang Ointment)in random.The course of treatment was lasted for 7 days.The clinical curative effect was compared between the two groups.ResultsAfter treatment,the score of anal distending pain and edema,and scores of symptom checklist 90(SCL－90)were all decreased significantly in the two groups with statistical differences(P＜0.05).After therapy,the score of anal distending pain and edema,and the score of SCL－90 were lower than those of the observation group (P＜0.05).The total effective rate in the observation group was 95.00%, which was higher than that of the control group(72.50%)(P＜0.05).ConclusionExternal application of homemade Jinhuang Ointment can obtain a remarkable in the treatment of postoperative anal edema of mixed hemorrhoids,and can effectively improve the clinical symptoms and facilitate the rehabilitation,which is worthy of promotion.
2017 Vol. 24 (31): 161-163 [Abstract] ( 190 ) HTML (35 KB)  PDF  (0 KB)  ( 41 )
164 The effect of needle warming moxibustion treating rheumatoid arthritis (Tongbi)and its impact on TNF-α,IL-6 and IL-37
HOU Xin-ju；MA Hong-mei；XIONG Wei
ObjectiveTo investigate the effect of needle warming moxibustion treating rheumatoid arthritis(RA,Tongbi) and its impact on TNF－α,IL－6 and IL－37.MethodsFrom September 2013 to January 2017,92 patients diagnosed with cold－damp obstruction type of RA were included in our hospital and were randomly divided into two groups on the basis of the random data table method.The control group (n=46) receivedwestern medicine only,while the observation group(n=46)received needle warming moxibustion treatment.Furthermore,the clinical efficacy and inflammatory factors were compared.ResultsAfter treatment,the level of TNF－α,IL－6 and IL－37 in the two groups were decreased,and those indexes in the observation group were significantly decreased than those in the control group (P＜0.05).The number of joints swelling and joint tenderness were decreased in both groups,and the indexes in the observation group were significantly fewer than those in the control group (P＜0.05).The total effective rate of the observation group was 93.48%, which was significantly higher than the control group (76.09%)(P＜0.05).Conclusion Needle warming moxibustion treating RA is effective and can improve the inflammatory response,thus it is worthy of popularization.
2017 Vol. 24 (31): 164-166 [Abstract] ( 183 ) HTML (33 KB)  PDF  (0 KB)  ( 43 )
167 Application of Continuous Nursing Model in Health Recovery of Discharged Elderly Patients with Coronary Heart Disease
XIAO Lu；HE Ye
ObjectiveTo analyze and explore the effect of continuous nursing model on the effect of treatment compliance,blood pressure and blood lipid in discharged elderly patients with coronary heart disease(CHD)so as to evaluate the effect of continuous nursing model on patients'health recovery.MethodsAltogether 110 elderly patients with coronary heart disease who were treated in our hospital from January 2015 to January 2016 were selected as the research objects and divided into the observation group and the control group according to different nursing modes,with 55 cases in each group.The observation group adopted continuous nursing mode,and the control group adopted general nursing mode.The compliance,blood pressure and blood lipid levels were compared between the two groups after discharge.ResultsThe medication compliance,diet compliance,moderate activity compliance,self－examination compliance and regular examination compliance of observation group were 87.27%,83.64%,69.09%,81.82%and 85.45%,significantly higher than those of control group(63.64%,67.27%,45.45%,58.18%and 65.45%),with statistically significant difference between the two groups(P＜0.05);the various blood pressure and blood lipid levels[diastolic blood pressure(DBP), systolic blood pressure(SBP),total cholesterol(TC)and triglyceride(TG)]of observation group were(75.11±8.14)mmHg, (120.12±15.42)mmHg,(4.41±0.38)mmol/L and(1.68±0.32)mmol/L,lower than those of control group[(79.05±8.57)mmHg, (127.64±16.12)mmHg,(4.67±0.45)mmol/L and(1.82±0.36)mmol/L],with statistically significant difference between the two groups (P＜0.05).ConclusionContinuous nursing mode can meet patients′health needs,establish healthy living habits for elderly patients with coronary heart disease and improve patients′quality of life.It can reduce blood pressure and blood lipid levels and is conducive to control the disease,which is worthy of clinical application.
2017 Vol. 24 (31): 167-169 [Abstract] ( 183 ) HTML (33 KB)  PDF  (0 KB)  ( 78 )
170 Influnence of root cause analysis method on the incidence of unplanned extubation in tubation patients
WEI Hua-ling
ObjectiveTo investigate the influnence of root cause analysis on the incidence of unplanned extraction of intubation patients.Methods42 postoperative intubation patients to our hospital from January 2015 to January 2016 were were selected selected as control group.Root cause analysis was used to explore the reason of unplanned extubation,and the corresponding rectification measures were put forward.42 postoperative intubation patients from February 2016 to Februray 2017 were selected as observation group,and rectification measures were used during nursing.The unplanned extubation incidence rate and family nursing satisfaction between two groups were compared.ResultsThe incidence of unplanned extraction was 4.76%in the observation group,compared with 21.43%in the control group and 97.62%in family care.Compared with 85.71%of the control group,the difference was statistically significant(P＜0.05).ConclusionThe using of root cause analysis is help to reduce the unplanned extubation incidence rate and enhance family nursing satisfaction,which is worthy of clinical application and promotion.
2017 Vol. 24 (31): 170-172 [Abstract] ( 146 ) HTML (31 KB)  PDF  (0 KB)  ( 62 )
173 Development and application of the device for maintaining limb function
LI Qing-lan ；CHEN Li-hua ；LI Yun-hong ；YANG Liu； LIU Xiao-lan
ObjectiveTo analyze the effect of adjuvant therapy in ICU patients with severe limb function.Methods 90 cases of ICU patients admitted to our hospital from July to December 2015,the patients were randomly divided into control group and observation group,45 cases in each group,The control group was treated with conventional restraint band and nursing,The observation group was used to maintain the limb function of the device to assist and care,compared the two groups of patients in the care process of the accident rate,limb circumference and limb edema scores and nursing satisfaction.Results The incidence rate of sudden accident in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P＜0.05).The limb size of the patients in the observation group was significantly shorter than the control group,and the difference was statistically significant(P＜0.05).The score of body edema was significantly lower in the observation group than in the control group,and the difference was statistically significant(P＜0.05).The satisfaction of the patients in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).ConclusionThe ICU patients with severe use of limb function to maintain the device to assist,is helpful to avoid the occurrence of sudden accident and to reduce the risk of limb edema.At the same time,It is helpful to improve patient satisfaction It is of great value and can be popularized in the patients with severe ICU.
2017 Vol. 24 (31): 173-175 [Abstract] ( 151 ) HTML (34 KB)  PDF  (0 KB)  ( 36 )
176 Clinical characteristics of cognitive impairment in patients with cognitive impairment after stroke and the effect of cooperative nursing
WU Xiao-hong ；TAO Jin-lan ；XIE Li-jing
ObjectiveTo observe the effect of collaborative nursing on cognitive impairment in patients with non－dementia cognitive impairment(CIND)after stroke.MethodsSixty patients with CIND who were treated in our hospital from June 2015 to January 2017 were selected as the experimental group,and 70 patients with normal cognitive impairment after stroke were selected for the control group,the experimental group of patients with collaborative care,the control group of patients with routine care.70 cases of CIND patients with clinical cognitive characteristics were analyzed and compared with the experimental group of patients in the implementation of collaborative care measures before and after the daily activities and cognitive ability.ResultsThe cognitive score,visual space and execution,language and other cognitive scores of Montreal Cognitive Assessment(MoCA)were significantly lower in the experimental group than those in the control group(P＜0.05).The scores of cognitive function(MMSE)and routine exercise ability(Barthel)were significantly improved in the experimental group (P＜0.05),and the difference was statistically significant(P＜0.05).Conclusion The cognitive impairment of CIND patients is the result of multiple cognitive domain combined damage,and according to the characteristics of different patients with the corresponding rehabilitation care can effectively improve the patient's daily activities and cognitive ability.
2017 Vol. 24 (31): 176-178 [Abstract] ( 197 ) HTML (35 KB)  PDF  (0 KB)  ( 49 )
179 Study on the effect of early nursing intervention on postpartum urinary retention
XIONG Hua-lan
ObjectiveTo analyze the delivery room's effect of early nursing intervention on postpartum urinary retention.Methods70 women who gave birth in our hospital from February 2015 to May 2016 were selected as survey subjects,and the digital table method was randomly divided into control group and observation group,with 35 cases in each group.the control group receivedroutine care,the observation group received early care in the delivery room,two groups of postpartum urinary retention were analyzed,first urination time,catheterization rate and so on.ResultsThe incidence of postpartum urinary retention in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05);The catheterization rate in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05);The first urination time in the observation group was shorter than that in the control group,the difference was statistically significant(P＜0.05).ConclusionProduction room early nursing intervention application effect is remarkable,help to reduce the incidence of postpartum urinary retention,the shortening of postpartum micturition time is worth applying.
2017 Vol. 24 (31): 179-181 [Abstract] ( 184 ) HTML (34 KB)  PDF  (0 KB)  ( 75 )
182 Study on the effect of abortion care to improve the adverse reaction induced abortion after the operation
CHEN Jin
ObjectiveTostudy the abortion care improvement of adverse reaction induced abortion postoperative effect.Methods184 cases collected from June to December 2016 in our hospital for treatmentof adolescent abortion,were randomly divided into experimental group and control group,the control group
receivedthe routine nursing,the experimental group of abortion care on the basis of routine nursing,the experimental group received abortion care on the basis of routine nursing,compared two groups of patients with anxiety,intraoperative pain and abortion syndrome rate.ResultsIn the experimental group,the anxiety score [(47.6±2.5)points]was significantly lower than the control group [(54.8±3.4) points],pain score[(4.1±1.2)points]was significantly lower than the control group[(6.2±2.3)points],the postoperative incidence of abortion syndrome(9.8%)than in the control group(22.8%),the differences was statistically significant(P＜0.01).ConclusionAbortion care can be used to reduce anxiety and pain in young people with induced abortion,and reduce the incidence of postoperative abortion syndrome.
2017 Vol. 24 (31): 182-184 [Abstract] ( 167 ) HTML (34 KB)  PDF  (0 KB)  ( 75 )
185 Control effect of painless ward standardized nursing for cancer pain patients with pain
WANG Shu-ying
ObjectiveTo investigate the influence of implementing normalized nursing in painless ward on pain control in patients with cancer pain.Methods94 patients with advanced cancer treated in our hospital from August 2015 to August 2016 were retrospectively analyzed.According to different nursing measures,they were evenly divided into research group and control group,47 cases in each group.In the research group,normalizednursing of painless ward was adopted,while in the control group,conventional care was used.The nursing effect was compared between the two groups.ResultsIn the research group,the pain alleviating rate was higher than that in the control group with a statistical difference(P＜0.05).There was no significant difference in pain score between the two groups before intervention(P＞0.05).After the intervention,the pain score in the research group was lower compared with that in the control group with a statistical difference (P＜0.05).The satisfaction rate in the research group was higher than that in the control group,which was displayedstatistical significance(P＜0.05).ConclusionIn the course of clinical nursing for patients with cancer pain, application of normalized nursing in painless ward can obtain a remarkable effect by alleviating patient′s pain and improving pain alleviation rate and nursing satisfaction,which is worthy of further study and promotion.
2017 Vol. 24 (31): 185-187 [Abstract] ( 152 ) HTML (33 KB)  PDF  (0 KB)  ( 62 )
188 Exploring the influence of rehabilitation nursing intervention on patients with lumbar intervertebral disc protrusion
ZHOU Yan ；LIU Yang-yang
ObjectiveTo explore the influence of rehabilitation nursing intervention on patients with lumbar disc protrusion.MethodsA total of 100 patients with lumbar disc herniation were randomly selected from December 2016 to March 2017 in our hospital.According to the different nursing measures,they were divided into two groups,research group and control group.In the research group,rehabilitation nursing intervention was adopted,while in the control group, routine nursing was used.The clinical nursing effect,disease recurrence rate,nursing satisfaction,and quality of life score in the two groups were compared.ResultsThe clinical nursing effect in the research group were significantly better than that in the control group (P＜0.05).The nursing satisfaction and score of quality of life in the research group were both significantly improved compared with those in the control group(P＜0.05).The recurrence rate in the research group was much lower than that in the control group (P＜0.05).The indexes mentioned above were all displayed statistical significance.ConclusionThe rehabilitation nursing intervention for patients with lumbar intervertebral disc protrusion can effectively improve the patient′s nursing satisfaction and quality of life,enhance the clinical nursing effect,and reduce the recurrence rate of the disease.It is worthy to be applied and promoted in clinical nursing.
2017 Vol. 24 (31): 188-190 [Abstract] ( 182 ) HTML (33 KB)  PDF  (0 KB)  ( 39 )
191 Clinical value of psychological nursing in nursing care of diabetic nephropathy
WEI Xiao-yan；DENG Hua；WANG Mei-rong
ObjectiveTo explore the clinical value of psychological nursing in the nursing of diabetic nephropathy.MethodsThe clinical data of 100 patients with diabetic nephropathy from January 2015 to January 2017 in the Department of nephropathy of our hospital were analyzed,they were randomly divided into two groups:the control group and the experimental group.The control group receivedroutine clinical nursing,the experimental group was given psychological nursing at the same time,the nursing effect and nursing satisfaction of the two groups were compared.Resultsthe total effective rate of the experimental group was 94%,and the mortality rate was 2%,The nursing satisfaction was 94%,the total effective rate was 84%in the control group,the mortality rate was 4%,and the nursing satisfaction was 82%,The nursing efficiency and satisfaction of the experimental group were significantly higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusionit is helpful for the treatment and nursing effect of diabetic nephropathy patients to receive effective psychological nursing intervention at the same time of systematic clinical treatment and nursing measures.
2017 Vol. 24 (31): 191-193 [Abstract] ( 169 ) HTML (31 KB)  PDF  (0 KB)  ( 45 )
194 Influence of emergency nursing process optimization on emergency efficacy and nursing satisfaction of emergency patients
OUYANG Hua
ObjectiveTo evaluate the effects of emergency nursing process for emergency patients emergency treatment and nursing satisfaction.MethodsFrom the emergency department of our hospital in 96 patients as the research object, the research time was from April 2015 to April 2017,according to the time of admission patients were randomly divided into study group and control group,among them,the study group(from April 2016 to April 2017)and 50 cases of application of emergency nursing process optimization measures,46 cases of the control group (from April 2015 to March 2016)the application of conventional nursing measures in emergency department,triage assessment time were compared between the two groups,the time of venous blood,rescue Success rate.ResultsThe study group triage assessment time, ECG monitoring time,venous blood collection time,intravenous medication time and treatment time were lower than the control group,while the success rate of rescue and nursing satisfaction were higher than control group,there was statistically significant difference(P＜0.05).ConclusionEmergency nursing process optimization can strengthen the emergency patients emergency treatment,improve the success the rescue and nursing satisfaction rate,worthy of recommendation.
2017 Vol. 24 (31): 194-196 [Abstract] ( 166 ) HTML (31 KB)  PDF  (0 KB)  ( 55 )
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