ObjectiveTo compare the efficacy of minimally-invasive percutaneous nephrolithotomy(MPCNL)and retroperitoneal laparoscopic ureterolithotomy(RLU)in the treatment of upper ureteral calculi.MethodsAltogether 202 cases of upper ureteral calculi patients who were treated in our hospital from January to December 2015 were retrospectively analyzed and divided into the MPCNL group(121 cases)and the RLU group(81 cases)according to the different treatment methods.The efficacy of the two groups was compared and the statistical analysis of length of operation,the amount of bleeding,length of stay,one-time lithotripsy success rate,repeated treatment rate,the incidence rate of complications and postoperative stone clearance rate was statistically analyzed between the two groups.ResultsThe length of operation and length of stay in the RLU group were shorter than those in the MPCNL group,the amount of bleeding in the RLU group was less than that in the MPCNL group,the one-time lithotripsy success rate and postoperative stone clearance rate in the RLU group were higher than those in the MPCNL group,the repeated treatment rate and the incidence rate of complications in the RLU group were lower than those in the MPCNL group,with statistically significant difference (P＜0.05).ConclusionThe operation time and length of stay of RLU in the treatment of upper ureteral calculi is shorter and the amount of bleeding is less,the curative effect is better than that of MPCNL.