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Quick Search     Adv Search 2016 Vol. 23, No. 34 Published: 2016-12-08   4 Experimental study on the construction of hepatic oval cell strain stably expressing HBx and M icroRNA-21 gene ZHANG Hong-hui ；XIE Bin-hui ObjectiveTo study the constructionmethod of stably expressing HBx and MicroRNA-21 gene of hepatic oval cell strain.MethodsOval cell strain (LE/6)in rat was cultured using LE culture medium,and HBVx sequence in plasmid of PcDNA3.1-HBVx was used as the template,and target gene fragment A was obtained by PCR method amplification.HBx target gene fragment and plasmid vector pEGFP-Nl were conducted double enzyme digestion,and the recombinant plasmid obtained by linearization was named as pEGFP-HBx.Competence of Escherichia coli DH5a was transformed by recombinant plasmid to conduct screening and culture.The plasmid was transfected into oval cells by liposome method (the pEGFP-HBx group)while plasmid vector pEGFP-Nl was transfected by liposome method(the pEGFP-NIplasmid group).Finally,Pre-MicroRNA-21 and HBx-LE/6were given co-culture,and after 24 h culture,fluorescence expression of transfected cellwas observed by fluorescencemicroscopy.ResultsThe expression volume of GFP in pEGFP-HBx determined by fluorescence quantitative PCR instrumentwas 92.28%,with strong expression degree.After the co-culture of Pre-MicroRNA-21 and HBx-LE/6 was completed,the transcription level of MicroRNA-21 in pEGFPHBx groupmeasured by instrumentwas(1.77±0.24),and itwassignificantly higher than thatin the pEGFP-NIplasmid group (0.36±0.21),and differences between the two groupswas statistically significant(P＜0.05).ConclusionThe stable expression of HBx and MicroRNA-21 gene in hepatic oval cell strain is successfully constructed,which provides the experimental basis for further study on the relationship between HBx protein,miRNA-21,hepatic oval cells and liver cancer. 2016 Vol. 23 (34): 4-6转10 [Abstract] ( 143 ) HTML (33 KB)  PDF  (0 KB)  ( 36 ) 7 Clinical investigation of psychological integration in patients with kidney transplantation ZHOU Qin-fei；ZHANG Ya-lin ObjectiveTo investigate the anxiety and depression of psychological state and so on and psychological integration status of patients after kidney transplantation,and analyze the psychological experience of patients after kidney transplantation.Methods303 cases after kidney transplantation treated by three affiliated hospitals of Central South U-niversity from May to September 2012 were included.Formulary questionnaire including basic information table,selfrating anxiety scale(SAS),self-rating depression scale (SDS)and psychological integration scale were used to investigate the psychological integration of patients after kidney transplantation and the correlation between psychological integration and psychological state.ResultsSAS score of patients with kidney transplantation was (40.99±10.08)points, SDS score was(44.84±11.93)points,and SAS and SDS score were higher than those of the norm[(37.23±12.59)points, (41.88±10.57)points](P=0.000).The vastmajority(84.2%)of patientswith kidney transplant believed that the transplanted kidney had become a partof the body,but still a small part of the patients(11.5%)were not sure even some patients(21.8%)thought that the kidney transplanted were still a foreign body.Factor analysis of psychological integration was conducted and two factors extracted—organ integration and the relationship with donor.Correlation analysis showed that organ integration and the relationship with donor were significantly correlated with SAS and SDS score (P＜0.05).ConclusionMost of patients with kidney transplant have good psychological integration,but there is still a part of patients with persistent abnormal psychological integration process,early identification of psychological integration problems of patients and timely intervention can improve the psychological status and quality of life of patientswith kidney transplantation. 2016 Vol. 23 (34): 7-10 [Abstract] ( 128 ) HTML (36 KB)  PDF  (0 KB)  ( 32 ) 11 Application progress of gene identification technology in species identification of Triculinae QIU Min；CHEN Qing；KE Xue-mei Triculinae is known to be the intermediate host of Paragonimus and Asian Schistosomes,and the accuracy of identification result of Triculinae is essential for the control of parasitic diseases caused by Paragonimus and Asian Schistosomes.Due to its small size and lack of significant appearance feature,it′s hard to identify Triculinae accurately. With the development ofmolecular biology and bioinformatics,it is possible to identify Triculinae species using genetic method now.This paper reviews gene segements frequenctly used in species identification and their application to Triculinae identification,and discusses the obstacle for further use. 2016 Vol. 23 (34): 11-14 [Abstract] ( 141 ) HTML (43 KB)  PDF  (0 KB)  ( 35 ) 15 Research progress on treatment for chronic osterom yelitis with absorbable biomaterials LIU Yi-xiu BAIXi-zhuang A Liang Osteomyelitis is a common inflammatory bone disease caused by pyogenic bacteria.Non-biodegradable polymethylmethacrylate(PMMA)bone cement containing antibiotics has been extensively used as a prophylaxis and for the treatment of bone infections,which needs a second surgery to remove PMMA.To date,there are three ideal kinds of absorbable biomaterials including polylactic acid,poly-ε-caprolactone,poly-(D,L-lactide-co-glycolide).The three kinds of esters have good biodegradation and biocompatability,but the PLA and PCL take long time to degrade.PLGA takes porper time to degrade,which fulfill the antibiotic releasing and the new bone formation.The composite of esters and hydroxyapatite,β-tricalcium phosphate can greatly improve their physicochemical properties,which is better than each single biomaterial.In this paper,the progress on biodegradablematerials for osteomyelitis treatment is reviewed. 2016 Vol. 23 (34): 15-17 [Abstract] ( 141 ) HTML (32 KB)  PDF  (0 KB)  ( 33 ) 18 Analysis of incidence and risk factors of bacterial vaginosis for fertile age women in community QIN Xing-xiang； QIN Yu-ming ；KUANG Fang-mei ；JIANG Cui-ping ；XU Xue-ling ObjectiveTo investigate the incidence and the related risk factors of bacterial vaginosis for fertile age women in local area.MethodsVaginal secretion examination results and questionnaires 2483 fertile agewomen in local area from June 2015 to Febrnuary 2016 were counted and analyzed.Unconditional single factor and multi-factor Logistic regression analysiswere used to analyze the risk factors.ResultsThe prevelance rate of bacterial vaginosis in fertile age women was 15.5%(384/2483)in local area.Age,educational level,economic income,urogenital disease history,reproductive history,frequency of sexual life,using condoms,health habits,clinical symptoms and examination and so on was associated with bacterial vaginosis in fertile age women(P＜0.05);cleaning up inside the vagina,use health care pad in non menstrual period,artificial abortion times increased and the high frequency of sexual life was risk factors of bacterial vaginosis,and the using condomswas a protective factor for bacterial vaginosis(P＜0.01).ConclusionThe prevelance rate of bacterial vaginosis in local area for fertile age women is relatively high.Paying attention to sexual life and hygiene habits,at the same time,strengthening the propaganda of knowledge about health care,which play an active role in reducing the infection of bacterial vaginosis. 2016 Vol. 23 (34): 18-21 [Abstract] ( 151 ) HTML (40 KB)  PDF  (0 KB)  ( 26 ) 22 Analysis of clinical treatment and recurrence in patients with inguinal hernia by tension-free hernia repair LIU Hui-bin ObjectiveTo explore the clinical effect and safety of tension-free hernia repair treating inguinal hernia.MethodsClinical related data of 78 patients with inguinal hernia treated in our hospital from May 2012 to February 2016 were retrospectively analyzed.32 cases as control group were treated by traditional hernia repair,and the other 46 cases as observation group were treated by tension-free hernia repair.The operation time,length of stay,length of incision,blood loss during operation were compared between two groups.Pain after operation were compared between two groups by using visual analog score(VAS).The incidence rate of postoperative complication and recurrence rate and incidence rate of pain between two groupswere compared.ResultsThe operation time and hospitalization time of observation group were significantly shorter than the control group (P＜0.05),blood loss during operation in observation group was significantly less than that of control group,and incision length in observation group was significantly shorter than that of control group (P＜0.05).The incidence rate of scrotal edema and local lump sensation in observation group after operation was significantly lower than that of control group (P＜0.05).VAS score 2 days after operation in observation groupwassignificantly lower than thatofcontrolgroup(P＜0.05).The recurrence rateand incidence rate ofpain after 6months operation in observation group were significantly lower than those of control group(P＜0.05).ConclusionThe effectof tension-free hernia repair treating inguinal hernia is significantwith lower recurrence rate and fewer postoperative complication compared with traditional hernia repair.It isworthy of clinical popularization. 2016 Vol. 23 (34): 22-24 [Abstract] ( 127 ) HTML (32 KB)  PDF  (0 KB)  ( 33 ) 25 Prevention effect for gastric and duodenal injury of Pantoprazole and Helicobacter pylori eradication therapy in elderly patients treated with Aspirin LIU Ren-peng ObjectiveTo explore the prevention effect for gastric and duodenal injury of Pantoprazole and Helicobacter pylori eradication therapy in elderly patients treated with Aspirin.Methods86 elderly patientswith peptic ulcer treated in our hospital from November 2014 to November 2015 and they were divided into control group and observation group in accordance with the admission order of even and odd-number.43 patients in control group were given Helicobacter pylori eradication therapy,while 43 patients in observation group were treated by Pantoprazole.The gastrointestinal injury,disease progression disease improvement situation in patients between two groups were compared.ResultsThe gastrointestinal injury rate and gastrointestinal injury degree in patients of observation group was obviously lower than that of control group respectively (P＜0.05).The disease progression,disease improvement situation of observation group were better than those of control group and the differences were statistically significant(P＜0.05).ConclusionPantoprazole can give more protection for stomach and duodenum of elderly patients treated with Aspirin than Helicobacter pylori eradication therapy,ofwhich the anti-acid treatmenteffect ismore ideal. 2016 Vol. 23 (34): 25-27 [Abstract] ( 137 ) HTML (29 KB)  PDF  (0 KB)  ( 42 ) 28 Effect of Enalapril combined with calcium carbonate vitam ine D3on bone m ineraldensity ofelderly patientswith essentialhypertension and osteoporsis CHEN Ping-jun ；WANG Xia ；HUANG Xiao-hong ObjectiveTo observe the effect of Enalapril combined with calcium carbonate vitamine D3on bonemineral density(BMD)of the elderly patientswith essential hypertension and osteoporosis.MethodsFrom May 2014 to December 2015,a total of 63 elderly patients with essential hypertension and osteoporosis in our hospital were selected as study object and randomly and double-blindly divided into group A(n=32)treated by Enalaprilwith calcium carbonate vitamine D3and group B (n=31)without Enalapril.The two groupswere observed for one year,the levels of 25-OH-vitamin D,serum calcium(Ca2+),serum phosphorus(P),alkaline phosphatase(ALP),parathyroid hormone(PTH),osteocalcin weremeasured before and 3,6,9,12 months after treatment.Bonemineral density (BMD)of lumbar vertebrae and neck weremeasured before and after treatment.ResultsThere was no significant difference in baseline values of serum parameters between two groups(P＞0.05).The total serum 25-OH-vitamin D levels in two groupswere increased 12months after treatment,and which 9 and 12months after treatmentwas significantly higher than the baseline values,however,the levels of 25-OH-vitamin D in two groupswere lower than normal value(30 ng/ml),there was no significnt statistical difference in the levels of 25-OH-vitamin D between two groups(P＞0.05).12months after treatment,serum Ca2+levels of two groups were elevated and within the normal range,no hypercalcemia occurred;serum Ca2+levels of two groups 6,9 and 12 months after treatment compared to the baseline valueswere significantly increased(P＜0.05);there was no statistically significant difference in serum Ca2+levels oftwo groups (P＞0.05).Osteocalcin,PTH,ALP,P compared with baseline values did not change significantly,there was no significant difference between two groups(P＞0.05).BMD(L1-4)value after treatment for one year in group A was significantly higher than that before treatment(P＜0.01);BMD value after treatment for one year in B group compared with before treatment had no obvious change (P＞0.05);after treatment for one year,BMD (L1-4)between two groupswere compared,and the difference was statistically significant(P＜0.05).BMD (neck)values after treatment for one year in two groupswere no higher than before,and there was no statistical difference in BMD(neck)between two groups(P＞0.05).ConclusionBMD value was obviously increased in the elderly patientwith essential hypertension and osteoporosiswho have taken Enalapril and calcium carbonate vitamine D3after treatment for one year. 2016 Vol. 23 (34): 28-31 [Abstract] ( 146 ) HTML (41 KB)  PDF  (0 KB)  ( 29 ) 32 Effect com parision of drag line intubation and incision-thread-draw ing procedure treating high com p lex anal fistula and influence on anorectal pressure LIChong ObjectiveTo compare the effect of drag line intubation and incision-thread-drawing procedure treating high complex anal fistula and influence on anorectal pressure.Methods84 patientswith high complex anal fistula treated by our hospital from September 2013 to June 2015 were selected and they were randomly divided into two groups and experimental group(n=42)was treated by drag line intubation,control group(n=42)was treated by incision-thread-drawing procedure.Cure rate,healing time,anorectal pressure from the anus20mm and 30mm(20mm and 30mm systolic pressure and resting pressure)and recurrence rate when patients were followed-up for 6 months between two groups was compared respectively.ResultsThe healing time of experimental group was significantly shorter than that of control group(P＜0.05).Compared with before operation,20mm and 30mm systolic pressure and resting pressure after 3months healing in two groupswere decreased(P＜0.05).20mm and 30mm systolic pressure and resting pressure after 3months healing in experimental group were higher than those of control group (P＜0.05).There was no significant difference of cure rate and recurrence rate when patientswere followed-up for 6months(P＞0.05).ConclusionThe effect of drag line intubation treating high complex anal fistula is better than that of incision-thread-drawing procedure,cure time is shortened,and it has little influence on anorectal pressure.It isworthy of promotion. 2016 Vol. 23 (34): 32-34 [Abstract] ( 135 ) HTML (31 KB)  PDF  (0 KB)  ( 31 ) 35 Application of facial nerve motor evoked potential in acoustic neuroma surgery ZENG Hai-lan ；YANG Rui-jin ；JIANG Qiu-hua；SONG Hai-min ；LUO De-fang ObjectiveTo investigate predictive effect of facial nerve motor evoked potential(FNMEP)monitoring on postoperative facial nerve function in acoustic neuroma surgery.MethodsFrom June 2014 to April 2016,54 patients with of acoustic neuroma treated by surgery in Department of Neurosurgery of People′s Hospital of Ganzhou City were selected as research object,facial nerve function of 34 cases among whichmonitored by intraoperative FNMEP were as observation group,the other 20 cases were as control group,all patients were jointly detected by electromyogram and brainstem auditory evoked potential and body sensory evoked potentials.Postoperative neurological function of two groupswere evaluated by postoperative reference of House-Brackmann(H-B)facial nerve grading standards.ResultsIn the observation group,patients of H-B gradeⅠ and gradeⅡ were 30 cases,1 case of H-B gradeⅢ,1 case of H-B gradeⅣ,1 case of H-B gradeⅤ,1 case of H-B gradeⅥ,postoperative facial nerve function of 30 caseswere good,the good ratewas 88.24%(30/34);in the control group,patients of H-B gradeⅠand gradeⅡwere 13 cases,2 cases of H-B gradeⅢ,3 cases of H-B gradeⅣ,1 case of H-B gradeⅤ,1 case of H-B gradeⅥ,postoperative facial nerve function of 13 caseswere good,the good rate was 65.00%(13/20),the good rate of facial nerve function in two groups had significant difference (P＜0.05).ConclusionFNMEP can predict the postoperative facial nerve function,which can improve and supplement themonitoring techniques of facial nerve function in the present operation. 2016 Vol. 23 (34): 35-37 [Abstract] ( 146 ) HTML (31 KB)  PDF  (0 KB)  ( 35 ) 38 Effect assessment of targeted health education for male patients with schizophrenia according to the course of disease YANG Ying-ying；GUO Bao-zhao；SUI Wen ObjectiveTo evaluate the effects of targeted health education on the compliance ofmedication and social function ofmale patientswith schizophrenia according to the course of disease.Methods126 hospitalized male patients in Male OneWard of Youfu Hospital of Binzhou City from January to June 2015 according to the diagnostic criteria for schizophrenia(DSM-IV))and no seriousphysical illnesswere selected as research object,and theywere randomly divided into observation group(odd numbers group)and control group(even numbers group)by the order of hospitalization.Patients in the observation group were given targeted health education according to the course of disease and setup differenteducational objectives in different stages of the disease treatment and rehabilitation;patients in the control group were used conventionalmethodsofhealth education in psychiatric department,medication complianceand social function in two groups were evaluated in 6 months after discharge.ResultsThe compliance of the observation group was 87.30%, better than 76.19%of the control group,and the difference was statistically significant(P＜0.05).There was statistically significant difference of occupation and work,parents function,social activities outside the home,family function,interest and concern to the outside world,responsibility and planning in two groups among SDSS (P＜0.05).ConclusionAccording to the course of disease,the implementation of targeted health education for male patients with schizophrenia can significantly improve themedication compliance and social functional rehabilitation,so as to improve the quality of life of patients. 2016 Vol. 23 (34): 38-40转43 [Abstract] ( 147 ) HTML (35 KB)  PDF  (0 KB)  ( 37 ) 41 Effect analysis of nerve interventional therapy in the treatment of cerebrovascular disease XIONG Feng；TANG Si-zhi；LUOWei ObjectiveTo analyze clinical effects of nerve interventional therapy for cerebrovascular diseases.Methods200 patients with cerebrovascular diseases in our hospital from January 2010 to January 2016 were selected as study objects and divided into control group and observation group according to the treatment method,100 cases in each group.Patients in the control group were treated with drugs conservative treatment,patients in the observation group were given nerve interventional therapy,Clinical treatment effects,satisfaction,complications and recurrence of two groups were compared.ResultsThe total effective rate of the observation group was 92%,significantly higher than 71% in the control group,and the difference was statistically significant(P＜0.01);satisfaction,total incieeace rate of complications and recurrence rate in the observation group was better than that in the control group,and the difference was statistically significant(P＜0.05).ConclusionNerve interventional therapy in the treatment of cerebrovascular disease has significant effect,high satisfaction of patients,high safety,lower incidence rate of complications and risk of recurrence. 2016 Vol. 23 (34): 41-43 [Abstract] ( 144 ) HTML (33 KB)  PDF  (0 KB)  ( 26 ) 44 Effects of Shenxiong G lucose Injection in the treatment of acute cerebral infarction and its effect on nerve function and hemorrheology LIAO Hua-yin； HU Qiong-li ；BAO Ze-yan ；ZHONG Shui-sheng ObjectiveTo investigate effects of Shenxiong Glucose Injection in the treatment of acute cerebral infarction and its effect on nerve function and hemorrheology.Methods114 cases of acute cerebral infarction patients in our hospital from December 2014 to April 2016 were selected and randomly divided into research group and control group, 57 cases in each group.Patients in the control group were treated with Troxerutin brain protein hydrolyzate based on conventional therapy,patients in the research group were treated with Shenxiong Glucose Injection combined with Troxerutin brain protein hydrolyzate.The total effective rate,neurological deficit scores,hemorheolog parameter and SF-36 score for evaluating quality of life before and after treatment of two groups were compared.ResultsThe total effective rate in the research group was80.7%,higher than 61.4%in the control group,and the differencewas statistically significant(P＜0.05).Therewere no significant difference in neurological deficit scores,hemorheolog parameter and SF-36 score before treatment(P＞0.05).After treatment of 15,30 and 60 d,the neurological deficit scores in the research group was lower than that in the control group(P＜0.05);after treatment,the hemorheolog parameter such aswhole blood highshear viscosity,whole blood low-shear viscosity,hematocrit,platelet aggregation of the research group was lower than that of the control group (P＜0.05);the SF-36 score of the research group was higher than that of the control group,and the difference was statistically significant(P＜0.05).ConclusionShenxiong Glucose Injection hasexacteffect in the treatment of acute cerebral infarction,which can effectively restore neurological function,improve hemorrheology,improve the quality of life of patients.It isworthy of clinical popularization and application. 2016 Vol. 23 (34): 44-46 [Abstract] ( 139 ) HTML (35 KB)  PDF  (0 KB)  ( 36 ) 47 Clinical app lication of laparoscopic surgery in the treatment of upper ureteral calculi complicated with ureteral stricture WANG Jun； LIU Fang ；YIRui ObjectiveTo explore the clinical effect of laparoscopic surgery in the treatment of upper ureteral calculi complicated with ureteral stricture.Methods36 patientswith upper ureteral calculiand ureteral stricture in our hospital from January 2010 to June 2016 were selected and randomly divided into the observation group and the control group, 18 cases in each group.The observation group was treated with laparoscopic surgery,the control group was treated by percutaneous renal surgery.The operation time,length of stay,and postoperative analgesic use time in the two groups were recorded,the clinical effect and the incidence rate of postoperative complications were compared between the two groups.ResultsThe operation time,postoperative analgesic use time of the observation group was shorter than that of the control group,with significant difference (P＜0.05).There was no significant difference in the length of stay between the two groups (P＞0.05).The calculi clearance rate and the incidence rate of adverse reactions in the two groups were compared,the difference was not statistically significant(P＞0.05).ConclusionLaparoscopic surgery in the treatment of upper ureteral calculiwith ureteral stenosis can significantly reduce the recovery time of patients after treatment,which has a low incidence of adverse reactions,with significant clinical advantages. 2016 Vol. 23 (34): 47-49 [Abstract] ( 167 ) HTML (32 KB)  PDF  (0 KB)  ( 32 ) 50 Clinical effect of app lication of ureteroscopic holm ium laser lithotripsy in the treatment of ureteral calculi LISi-hua； LIU Cong； LIN Yue-yue； LAIZai-chi ；FAN Han-gong ObjectiveTo explore the clinical effect of application of ureteroscopic holmium laser lithotripsy in the treatment of ureteral calculi.Methods84 ureteral calculi patients in our hospital from September 2015 to September 2016 were selected and randomly divided into the ureteroscopic holmium laser lithotripsy group and the pneumatic lithotripsy group,42 cases in each group.The clinical total effective rate,pain degree and daily functional activitieswere compared between the two groups.ResultsThe total effective rate of the ureteroscopic holmium laser lithotripsy group was 97.62%,which was higher than 80.95%of the pneumatic lithotripsy group,with significant difference(P＜0.05).The score of LASand VASof the two groups after treatmentwas lower than that before treatment,with significant difference (P＜0.01).The score of LASand VAS of the ureteroscopic holmium laser lithotripsy group after treatmentwas lower than thatof the pneumatic lithotripsy group after treatment,with significantdifference(P＜0.01).ConclusionThe effectofureteroscopic holmium laser lithotripsy in the treatment of ureteral calculi is accurate,which can significantly ease the pain,improve the life activity function. 2016 Vol. 23 (34): 50-52 [Abstract] ( 127 ) HTML (33 KB)  PDF  (0 KB)  ( 35 ) 53 Latest effect observation of laparoscopic sleeve gastrectom y in treating obesity combined with type 2 diabetesmellitus LIXiao-long；ZHAO Hao-liang；HAN Jian-li ObjectiveTo explore the latest effect of laparoscopic sleeve gastrectomy(LSG)in treating obesity combined with type 2 diabetesmellitus.Methods12 obesity patients combined with type 2 diabetesmellitus conducted LSG in Affiliated Dayi Hospital of Shanxi Medical University from April 2013 to May 2015 were selected.Followed-up for 6 months after operation,the changes of related index like weight,body mass index (BMI),excess weight loss rate (EWL%),fasting plasma glucose (FPG),fasting insulin (FINS)and homeostatic model assessment of insulin resistance (HOMA-IR)of patients before and after operation were compared.Results12 cases operated successfully,no conversion to open surgery during operation and no serious complicationswere found after operation.Postoperative followed-up for 1,3 and 6months,weight,BMI,FPG,FINSand HOMA-IR of patients at each time after operation was lower than that before operation(P＜0.05);EWL%was in upward trend(P＜0.05).ConclusionLSG in treating obesity combined with type 2 diabetesmellitus has effective latesteffects. 2016 Vol. 23 (34): 53-55 [Abstract] ( 150 ) HTML (34 KB)  PDF  (0 KB)  ( 40 ) 56 Clinical effect analysis of small incision thyroidectom y in the treatment of thyroid nodules ZHOU Wei ObjectiveTo study the clinical effect of small incision thyroidectomy in the treatment of thyroid nodule.Methods82 patients with thyroid nodules in Department of Surgery of the hospital from July 2014 to February 2016 were randomly divided into study group(n=41)and control group(n=41).Patients in the control group were treated with traditional thyroidectomy and patients in the study group were treated with small incision thyroidectomy.Operation time, intraoperative blood loss,surgical incision,first ambulation time,exhaust time,defecation time and hospitalization time after opration,incidence of incision adhesion and dysphagia etc.complication between two groupswere compared.ResultsOperation time and intraoperative blood loss in the study group was(45.52±6.63)min and(38.41±6.45)ml respectively, significantly less than(80.87±7.82)min and(77.38±7.66)ml in the control group;the incision in the control group was (8.17±0.35)cm,significantly larger than(4.63±0.42)cm in the study group;in the study group,the time of hospitalization was(3.78±0.57)d,significantly shorter than(8.12±0.69)d in the control group;the complication rate in the study group was significantly lower than that in the control group (7.32%vs 21.95%,P＜0.05).ConclusionThyroidectomy with small incision thyroidectomy can reduce intraoperative blood loss and time,the rate of complication is lower than that of traditional technique.It can shorten the hospitalization time and reduce patient′s pain,less invasive,which can be widely used in clinical treatment of thyroid nodule. 2016 Vol. 23 (34): 56-58转81 [Abstract] ( 139 ) HTML (36 KB)  PDF  (0 KB)  ( 36 ) 59 Effect analysis of bone morphogenetic protein－2 on lumbar interbody fusion ZHENWan-yuan； YAN Yan-xiang ；XIONG Chang-jun； WANGGuan-qing ；WU Rui ObjectiveTo observe the therapeutic effect of BMP-2 on lumbar interbody fusion.Methods106 patients with lumbar degenerative disease in Department of Orthopedics of our hospital form July 2011 to January 2016 were selected and divided into BMP-2 interbody fusion group (the bone repairmaterial of BMP-2 were filled in Cage,n=57) and traditional fusion group(autogenous boneswere filled in Cage,n=49)according to the differentways of repair.Average time during the operation and average intraoperative blood losswere compared between two groups,the rate of screw malposition and Cage shift loss and value of relative intervertebral height loss after operation for the firstweek,4th,6th,8th, 12th,24thweek,ODIand JOA before operation and after operation for the 24thweek and radiographic results were compared between two groups.ResultsAverage time during the operation and average intraoperative blood losswere no signiflcant difference between two groups (P＞0.05).After the firstweek of operation,the rate of screw malposition in traditional fusion group was 1.53%and without screw malposition in BMP-2 interbody fusion group;after operation for the 24thweek,the rate of screw malposition in traditional fusion group was 15.30%and 3.51%in BMP-2 interbody fusion group,and the difference between two groups was statistically significant(P＜0.05).The rate of Cage shift in traditional fusion group was 4.08%after operation for the 4thweek and without Cage shift in BMP-2 interbody fusion group;one Cage (1.75%)shifted in BMP-2 interbody fusion group until the 6thweek of postoperation;after operation for the 24thweek,the rate of Cage shift in traditional fusion group and BMP-2 interbody fusion group was respectively 20.41%and 7.02%,there was significant difference between two groups(P＜0.05).Relative intervertebral height in the traditional fu-sion group and BMP-2 interbody fusion group was(2.11±0.40)mm and(0.52±0.60)mm,and the difference was statistically significant (P＜0.05).The preoperative ODI score and JOA score in traditional fusion group was respectively (40.55±10.35)scores,(13.03±3.45)scores,and(39.32±9.63)scores,(14.56±2.17)scores in BMP-2 interbody fusion group, while after operation for the 24thweek,ODIscore and JOA score in the two groups was respectively (17.2±8.4)scores, (22.01±3.41)scores and (7.5±3.3)scores,(28.42±1.22)scores,therewas statistical difference (P＜0.05).ConclusionThe lumbar interbody fusion surgery using BMP-2 bone repairmaterials which replaces autologous bone not only can provide immediate biological stability,achieve effective structural support,but also can promote the recovery intervertebral disc height of patients and obviously improve the patient′spain symptoms. 2016 Vol. 23 (34): 59-62转88 [Abstract] ( 164 ) HTML (42 KB)  PDF  (0 KB)  ( 30 ) 63 Effect analysis of transpedicular intervertebral bone graft and short segment internal fixation in the treatment of thoracolumbar vertebral com pression fractures YAN Song ；MENG Fan-sheng； DONG Wei ObjectiveTo observe the clinical effects of transpedicular intervertebral bone graft and short segment internal fixation in the treatment of thoracolumbar vertebral compression fractures.MethodsAltogether 200 cases of patients with thoracolumbar vertebral compression fractures who were admitted into the hospital from January 2013 to June 2016 were selected as research object and divided into control group and observation group according to the different treatmentmethods,with 100 cases in each group,patients in the control group was treated simply with the short segment pedicle screw rod fixation system,while patients in the observation group was treated with transpedicular intervertebral bone graft on the basis of the control group.Surgical outcomes and fracture recovery of two groups was compared.ResultsNo obvious statistical difference was seen between operative time,intraoperative blood loss,length of stay and fracture recovery time of two groups(P＞0.05).The incidence rate rapture and loosening of internal fixation in the observation group showed great lower than control group,with a statistical difference (P＜0.05).The postoperative visual analogue score (VAS)pain score in the observation group and control group was (1.7±0.5)scores,(4.9±2.4) scores,with a statistical difference between two groups(P＜0.05).The vertebral body lost height postoperatively in the observation group was(4.1±1.3)%,with (7.9±1.8)%in the control group,and the difference was statistically significant (P＜0.05).ConclusionTranspedicular intervertebral bone graft and short segment internal fixation demonstrates in the treatment of thoracolumbar vertebral compression fractures has excellent effect,which significantly reduces patients′pain and promotes function recovery of postoperative fracture. 2016 Vol. 23 (34): 63-65 [Abstract] ( 133 ) HTML (33 KB)  PDF  (0 KB)  ( 35 ) 66 Effect and attenuation of compound Kushen Injection combined with Gem citabine and Cisp latin in treating pancreatic cancer SUN Yu-shu ObjectiveTo compare effect and adverse reactions of compound Kushen Injection combined with Gemcitabine and Cisplatin(GP)and simple GP in treating pancreatic cancer.Methods70 patientswith pancreatic cancer in our department from January to December 2015 were divided into compound Kushen Injection combined with GP (Kushen group,n=35)and simple GP (control group,n=35)by using random and controlmethod.The effectswere evaluated after treatment for 2 weeks,cancer pain relief,quality of life Karnofsky scores and adverse reactions in two groups were compared.ResultsThe difference of effects between Kushen group and control group had no statistical significance (P＞0.05).The pain relief rate in the Kushen group was 48.57%and 37.14%in the control group,and the difference was statistically significant(P＜0.05).The improvement rate of quality of life in the Kushen group was 54.29%,with 31.43% in the control group,and the difference was statistically significant(P＜0.05).All of the difference of bonemarrow suppression,gastrointestinal reaction and liver toxicity between the Kushen group and the control group was statistically significant(P＜0.05).ConclusionCompound Kushen Injection can decrease adverse reactions of GP chemotherapy regimen, increase the chemotherapy tolerance of patients and enhance quality of life. 2016 Vol. 23 (34): 66-68 [Abstract] ( 148 ) HTML (33 KB)  PDF  (0 KB)  ( 38 ) 69 Clinical efficacy analysis of m icrowave ablation combined with transcatheter arterial chemoembolization and surgical resection for patients with primary hepatocellular carcinoma of BCLC-B WANG Xin-ting ；ZHANG Chuan-lei ；CHEN Xiao-qi ；CHEN Xin-ju ObjectiveTo compare survival and prognosis of microwave ablation combined with transcatheter arterial chemoembolization (TACE)and surgical resection for patients with primary hepatocellular carcinoma of BCLC-B.MethodsClinacal date of 40 patienswho were diagnosed as primary hepatocellular carcinoma of BCLC-B in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from January 2010 to June 2013 were retrospectively analyzed and divided intominimally invasive group and operation group according to the different treatment methods,each group of 20 cases,patients in theminimally invasive group was treated with microwave ablation combined with TACE,while patients in the operation group was treated by surgical resection,near and long-term treatment effect in two groups were compared.ResultsThe 3-year survial rates were 85%in theminimally invasive group,and 55%in the operation group,and the difference was statistically significant(P=0.04).ConclusionThe efficacy ofmicrowave ablation combined with TACE in the treatment of primary hepatocellular carcinoma of BCLC-B is affirmat,and it could be considered as the first-line treatmentmethod for patientswith primary hepatocellular carcinoma of BCLC-B. 2016 Vol. 23 (34): 69-71 [Abstract] ( 149 ) HTML (32 KB)  PDF  (0 KB)  ( 29 ) 72 Effect analysis of Paclitaxel liposome combined with Cisp latin in the treatment of advanced non-small cell lung carcinoma ZHENG Wen； HUANG Kai-rong； HAN Yong-qing ObjectiveTo study the clinical effect of Paclitaxel liposome combined with Cisplatin in the treatment of advanced non-small cell lung cancer.Methods52 cases of patients with non-small cell lung cancer in our hospital from September 2013 to May 2016 were selected as observation object and randomly divided into control group and observation group,26 cases in each group.Patients in the control group were given Paclitaxel plus Cisplatin combined chemotherapy treatment,patients in the observation group were given Paclitaxel liposome combined with Cisplatin chemotherapy.The total effective rate and adverse reactions of two groupswere observed after treatment.ResultsThe total effective rate in the control group and the observation group was 50.00%,57.69%,there was no differences between two groups(P＞0.05);while incidence rate of pain,nausea and vomiting,rash,dyspnea among adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).ConclusionPaclitaxel liposome combined with Cisplatin in the treatment of patients with advanced non-small cell lung cancer is safe and effective,which isworthy of clinical application. 2016 Vol. 23 (34): 72-74 [Abstract] ( 178 ) HTML (32 KB)  PDF  (0 KB)  ( 36 ) 75 Effect of M atrine Injection on the level of pain,immune status and tumor marker in patientswith gastric cancer ZHU Sha ObjectiveTo explore effect of Matrine Injection on the level of pain,immune status and tumor marker in patientswith gastric cancer.Methods48 patientswith gastric cancer in our hospital from June 2015 to April 2016 were selected as study object and divided into two groups according to the differences of treatmentmethods,24 cases in each group.Patients in control group were treated with routine treatment of gastric cancer,while patients in observation group were treated with Matrine Injection on the basis of routine treatment of control group,pain related indexes,T lymphocyte subsets indexes and tumormarkers levels of two groups before and after the treatmentwere compared.ResultsThe pain related indexes,T lymphocyte subsets indexes and tumormarkers levels of two groups before treatmentwere compared, and the difference had no statistical significance (P＞0.05).The pain related indexes,T lymphocyte subsets indexes and tumormarkers levels of two groupswith the extension of time after treatmentwere continuously improved,and the levels of observation group were all better than those of control group (all P＜0.05).After treatment,pain related indicators,T lymphocyte subsets and the level of tumormarkers between two groups had significant difference(P＜0.05).ConclusionThe improvement role of Matrine Injection for the pain control,immunoregulation and disease treatment is active,so the comprehensive application value of Matrine Injection in the patientswith gastric cancer is higher. 2016 Vol. 23 (34): 75-77 [Abstract] ( 139 ) HTML (31 KB)  PDF  (0 KB)  ( 35 ) 78 Effect com parison of the water sac combined with oxytocin and oxytocin in term pregnancy induced labor GUAN Xiu-ying ；ZHANG Yuan-feng； LIN Hui-zhen ObjectiveTo analyze and compare the effect of water sac combined with oxytocin and oxytocin alone on term pregnancy induced labor,provide theoretical guidance and basis for induced labor for full term pregnancy in clinic.MethodsFrom June 2015 to June 2016,100 pregnant women of single birth,pole position,cervical Bishop score＜7 scores in our hospitalwere selected,and they were divided into two groups according to the date of admission:pregnant women from June to December 2015 were selected as control group,and pregnant women from January to June 2016 were selected as observation group,50 cases in each group.The observation group was given the water sac combined with oxytocin during the labor induction,and the control group was only given the oxytocin during the induced labor.The effect of induced labor of pregnantwomen was compared between the two groups.ResultsThe cervical Bishop score of pregnantwomen in the two groups before induced labour had no statistically significant difference (P＞0.05);12 h after induced labor,cervical Bishop score of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Time of induced labor to give birth,first stage of labor,total stage of labor of the observation group was shorter than those of the control group,the differencewas statistically significant(P＜0.05).The effective rate of induced labor in the observation group,rate of vaginal delivery was higher than the control group,rate of cesarean delivery was lower than that of the control group,the difference was statistically significant(P＜0.05).ConclusionApplication ofwater sac combined with oxytocin in the full-term pregnancy induced labor is better than oxytocin alone, can improve the rate of vaginal delivery of pregnantwomen,decrease cesarean section rate,it isworthy of clinical application. 2016 Vol. 23 (34): 78-81 [Abstract] ( 162 ) HTML (35 KB)  PDF  (0 KB)  ( 37 ) 82 Analysis of the clinical application of different contraceptivemethods carried at the immediate postoperative of high-risk abortion CHEN Hai-ping ；ZHOU Jing-jun ObjectiveTo observe and analyze the clinical effects of the condom,short-acting oral contraceptives,and placed intrauterine device for patients with high-risk abortion immediately.MethodsClinical data of 300 cases from February 2014 to February 2015 carried out the different contraceptivemethods in our hospital after a high-risk abortion was retrospectively analyzed,according to the intention patients were divided into three groups,with 100 cases in each group.Group A was given the V copper containing indomethacin intrauterine device,group B was given a shortacting oral contraceptives (Yasmin),group C was given condoms for birth control.The occurrence of repeated spontaneous abortion,irregular bleeding,infection,menstruation is abnormal,amenorrheawas observed in postoperative follow-up.Results1,3,6,12 months after artificial abortion operation,number of patients with repeated miscarriage in the group A and group B was less than thatof the group C,the difference was statistically significant(P＜0.05);the number of patients with postoperative infections,amenorrhea,irregular vaginal bleeding,menstrual cramps of the three groups had statistically significant difference (P＜0.5).ConclusionThe intrauterine device or short-acting contraceptives is a efficient reversible and birth controlmethods for patientswith high-risk abortion postoperative immediately,it can reduce the rate of repeated abortion and postoperative complications,and lower the adverse effects of reproductive health,is worthy of clinical application. 2016 Vol. 23 (34): 82-84 [Abstract] ( 128 ) HTML (34 KB)  PDF  (0 KB)  ( 35 ) 85 Effect of Saccharomyces boulardii on children with rotavirus enteritis CHEN Jing-fang；YANG Xiao-qing；LIN Bao-hua；SHEN Tong ObjectiveTo investigate the effect of Saccharomyces boulardii on children with rotavirus enteritis.MethodsFrom September 2011 to September 2013,a randomized case controlled trial was performed in Maternal and Children Health Care Hospital of Xiamen.All of the children were aged from 6months to 5 years and diagnosed as rotavirus enteritis.Patients were randomly divided into experimental group and control group.Oral rehydration salts and/or intravenous rehydration,Dioctahedral Smectite and licorice zinc were given to the control group routinely;on the basis of the treatment of the control group,Saccharomyces boulardii was given to the experimental group additionally.Dehydration correction time,heat recovery time and frequency of stool were detected in two groups.ResultsA total of 308 children were enrolled in this study at last,148 cases in the experimental group,160 cases in the control group.The effective rate was 87.2%in the experimental group,whereas 61.3%in the control group,and there was significant difference between the two groups(P＜0.05).In the experimental group,the total efficiency rate was 98.0%,while in the control group,the total efficiency rate was 83.2%,and there was also significant difference between the two groups(P＜0.05).The dehydration correction time and heat recovery time in the treatment group was(1.08±0.51)d and(0.77±0.35)d,respectively,(2.51± 0.84)d and(1.20±0.64)d in the control group,the difference was statistically significant(P＜0.05).ConclusionSaccharomyces boulardiiis effective in the treatment of pediatric rotavirus enteritis,the symptoms eliminated faster,and the diarrhea cured within shorter time.So it isworthy of clinical application and promotion 2016 Vol. 23 (34): 85-88 [Abstract] ( 127 ) HTML (37 KB)  PDF  (0 KB)  ( 31 ) 89 Noninvasive analgesia childbirth in obstetric intervention in clinical app lication ZHONGQiao-mei ；SU Yin-qing； YE Xiao-qin ObjectiveTo observe the clinical effect of non-invasive anodyne labor with Finecure instrument in the obstetrical department.Methods60 puerpera were delivered from September 1,2012 to October 30,2016 in obstetrical department of our hospital were selected.The subjects were divided into conventional group and non-invasive group according to the anodyne labormethods,30 cases in each group.The pain degree and total stage of labor as well as their evaluation score on the nursing care was observed.ResultsThe remission rate of labor pain for non-invasive group was better than that of conventional group (P＜0.01);the total stage of labor for conventional group was longer than that of non-invasive group(P＜0.01);the evaluation score of pain remission,calming of emotions,communication,education of related knowledge and signs of the conventional group was lower than that of non-invasive group (P＜0.01).ConclusionFinecure instrument is introduced to relieve the labor pain.In addition,its treatment cost is reasonable,without adverse reactions.It isworthy of extensive promotion and application in clinical practice. 2016 Vol. 23 (34): 89-91 [Abstract] ( 115 ) HTML (33 KB)  PDF  (0 KB)  ( 46 ) 92 Observation of the com prehensive application effect of Mifepristone in the patientswith endometriosis YUAN Ying-jiu； HOU Jian-li； DINGWen-qing ObjectiveTo observe and study the comprehensive application effect of Mifepristone in the patients with endometriosis.MethodsEighty patients with endometriosis in our hospital from April 2013 to July 2015 were selected as the research object,and patients were randomly divided into control group and observation group,with 40 cases in each group.The control group was treated with gestrinone,the observation group was treated with Mifepristone.Before and after treatment the WHOQOL-BREF score was used to evaluate the survival quality of patients;the total effective rate and level of endocrine(FSH,E2,LH)of patientswith different r-AFS staging at different time before and after treatment(3,6months ofter treatment)was compared.ResultsThe total effective rate of patientswith r-AFS stagesⅠtoⅡand stagesⅢ toⅣ in the observation group was 94.44%and 86.36%respectively,was higher than 72.22%and 68.18%of the control group (χ2=5.267,6.123,all P＜0.05);the levels of FSH,E2,LH at different time after the treatment were higher than those of the control group (P＜0.05);theWHOQOL-BREF scoreswere all higher than those of control group (P＜0.05).ConclusionComprehensive application of Mifepristone has better effect in patientswith endometriosis, and less influence on the endocrine of patients,the improvement role for the life quality of patients ismore obvious. 2016 Vol. 23 (34): 92-94 [Abstract] ( 133 ) HTML (33 KB)  PDF  (0 KB)  ( 31 ) 95 Effectiveness evaluation of Goserelin combined with Mirena in the treatment of adenom yosis WU Yi-xue； ZHONG Jian-ye ；YANG Xiu-yun ObjectiveTo study the efficacy of goserelin combined with Mirena in the treatment of adenomyosis.MethodsSeventy patientswith adenomyosis treated in the gynaecology department of our hospital from February 2014 to February 2015 were randomly divided into control group and observation group,with 37 cases in each group.The control group was treated with Goserelin,observation group was treated with Goserelin combined with Mirena.The treatment effect,indicators of uterine,dysmenorrhea and situation ofmenstruation of patients were compared between the two groups;the adverse reactions of two groups were observed.ResultsThe effective rate of the observation group was 94.29%,significantly higher than that of the control group(85.71%),the difference was statistically significant(P＜0.05).After treatment, the uterine volume and endometrial thickness of the observation group were significantly less than those of the control group,the differences were statistically significant(P＜0.05);the VAS pain score and PBACmenstrual volume score in the observation group were significantly lower than those in the control group,the difference was statistically significant (P＜0.05);the total incidence of adverse reactions,such as fatigue,osteodynia,climacteric symptoms,irritability,irregular vaginal bleeding,breast pain of the two groups had no statistically significant difference(P＞0.05).ConclusionGoserelin combined with Mirena has significant effect in the treatment of adenomyosis,can directly effect on uterine lesions,inhibit abnormal growth of endometrial,reduce disease activity,improve clinical symptoms,avoid the surgery effectively,has positive clinical significance. 2016 Vol. 23 (34): 95-97 [Abstract] ( 151 ) HTML (35 KB)  PDF  (0 KB)  ( 30 ) 98 Clinical effect evaluation of high speed turbine drilling method in the extraction ofmandibular im pacted tooth XIE Fan ObjectiveTo explore the clinical effect of high speed turbine drillingmethod in the extraction ofmandibular impacted tooth.Methods100 cases(104 teeth)of extraction mandibular impacted tooth from January 2015 to December in our hospitalwere selected and divided into the observation group and the control group according to the random number tablemethod,50 cases(52 teeth)in each group.The observation group was treated with high speed turbine drillingmethod,and the control group was treated with traditional crown cuttingmethod.The operative time,the postoperative pain degree,the degree ofmouth opening limitation and the incidence rate of dry socketwere compared between the two groups.ResultsThe operative time in the observation group was (22.3±5.2)minutes,which was shorter than (36.3±6.9)minutes in the control group,with significant difference(P＜0.05).The VAS score of the observation group after operation was(3.8±0.9)points,which was lower than(5.3±1.2)points of the control group,with significant difference (P＜0.05).The degree ofmouth opening limitation in the observation group was lower than that in the control group,with significant difference(P＜0.01).The incidence rate of dry socket in the observation group was 2.0%,which was lower than 12.0%in the control group,with significant difference(P＜0.05).ConclusionThe high speed turbine drillingmethod can effectively shorten the operation time,reduce the degree of postoperative pain and the extent ofmouth opening,and control the incidence rate of complications,it isworthy of clinical promotion and application. 2016 Vol. 23 (34): 98-100 [Abstract] ( 108 ) HTML (32 KB)  PDF  (0 KB)  ( 33 ) 101 Comparison of the effect of personalized all-ceram ic abutment combined with all-ceram ic crown restoration and Titanium abutment combined with all-ceram ic crown restoration in anterior dental im p lant restoration LIHong-bo ObjectiveTo compare the effect of personalized all-ceramic abutment combined with all-ceramic crown restoration and Titanium abutment combined with all-ceramic crown restoration in anterior dental implant restoration.Methods70 caseswith anterior dental implant restoration from March 2014 to March 2015 in our hospitalwere selected and divided into the observation group(33 cases,37 implants)and the control group(37 cases,40 implants)according to the different abutment.The observation group was given the combination treatment of personalized all-ceramic abutment and all-ceramic crown restoration,the control group was treated with the combination of personalized Titanium abutments and all-ceramic crown restoration.All the patientswere re-examined after implantation at 1,6,12months,included peri-implant probing,mobility,the contour of the crown (whether it was damaged)and other clinical examinations.The gingival bleeding index(GBI)and plaque index(PI)in the two groups were compared,the aesthetic satisfaction degree was also evaluated according to the statistical of Pink esthetic score(PES)and White esthetic score(WES).ResultsAll the 77 bone horizontal implants showed neither loosening nor damages in the contour of the crown postoperatively.Therewas no significant difference in the GBIand PIbetween the two groups at different time after implantation.There was no significant difference in the satisfaction degree of PES and WES between the two groups after implantation at 1 and 6months.The satisfaction degree of PESand WES in the observation group after implantation at 12 monthswas higher than that in the control group,with significant difference(P＜0.05).ConclusionIn the cosmetic anterior implant repair,the personalized all-ceramic abutment shows great superiority and better overall effect over personalized Titanium abutments,which isworthy of clinical promotion and application. 2016 Vol. 23 (34): 101-103 [Abstract] ( 127 ) HTML (32 KB)  PDF  (0 KB)  ( 33 ) 104 Clinical effect observation of combination of traditional Chinese and western medicine in the the treatment of amblyopia in children ZHANG Xiao-yong；CHEN Hui；YANG Xiao-min ObjectiveTo explore the clinical effect of combination of traditional Chinese and western medicine in the the treatment of amblyopia in children.Methods94 children with amblyopia in our hospital from January 2013 to June 2014 were selected and randomly divided into group A and group B,47 cases in each group.Group A was treated with combination of traditional Chinese and western medicine,and group B was treated with integrated treatment of western medicine.The therapeutic effect of the two groups was compared.ResultsThe total effective rate of group A was 97.87%,which was higher than 82.98%of group B,with significant difference(P＜0.05).ConclusionCombination of traditional Chinese and westernmedicine in the treatment of amblyopia in children can significantly improve the treatment effect,it isworthy of clinical promotion and application. 2016 Vol. 23 (34): 104-106 [Abstract] ( 130 ) HTML (31 KB)  PDF  (0 KB)  ( 39 ) 107 Value analysis of orthodontic traction in treating crowded dentition with severe periodontal disease PIAO Hu-xiong； LIYing ；CUIZhe-hao； XUAN Yun-ze ObjectiveTo explore the clinical effect of orthodontic traction in treating crowded dentition with severe periodontal disease.Methods26 cases of crowded dentition with severe periodontal disease from March 2013 to July 2015 in our hospitalwere selected as the research objects.All patientswere treated with orthodontic traction and followed-up for 1 year.Length of dental arch,alveolar density and inflammatory factors of patients after treatment were analyzed.ResultsWhen the appliance removed and one year after appliance removed,the length of dental arch was (86.8±3.3) mm and (85.4±4.1)mm respectively,which was longer than (74.2±3.6)mm before treatment,with significant difference (P＜0.05).One year after appliance removed,the alveolar density ofmaxillary central incisors,left upper central incisors and low maxillary central incisors was obvious higher than that before treatment,with significant difference (P＜0.05). When the appliance removed,the level of IL-1βand INF-αwas higher than that before treatment,with significant difference(P＜0.05).One year after appliance removed,the level of IL-1βand INF-αwas lower than that before treatment, with significant difference (P＜0.05).ConclusionOrthodontic traction in treating crowded dentition with severe periodontal disease has good effects,which can improve dentition status effectively,enhance dental health degree,and it is worthy of clinical promotion and application. 2016 Vol. 23 (34): 107-109 [Abstract] ( 115 ) HTML (35 KB)  PDF  (0 KB)  ( 34 ) 110 Effect of magnetic attachment on the restoration of elderly com plete overdenture and its influence on periodontal health LIU Liang-fang ObjectiveTo study the effect ofmagnetic attachment on the restoration of elderly complete overdenture and its influence on periodontal health.Methods136 elderly patientswith dentition defect from April 2011 to October 2015 in the pepartment of dentistry of our hospital were selected and randomly divided into the experience group and the control group,78 cases in each group.The control group was treated with conventional overdenture restoration of card ring retainer,the experience group was treated with overdenture restoration of magnetic attachment.The efficacy,periodontal health and the incidence rate of adverse reactions were compared.ResultsThe satisfaction rate of language function,comfort,denture appearance of the experience group was 94.12%,92.65%,97.06%respectively,which was higher than 54.41%,41.47%,50.00%of the control group,with significant difference(P＜0.01).The chewing efficiency,fixed force of the experience group was higher than that of the control group,with significant difference (P＜0.01).The indexes of SBI,GCF,alveolar bone height,periodontal pocket depth of the experience group was better than that of the control group,with significant difference(P＜0.01).The incidence rate of adverse reactions in the two groupswere 4.41%,the difference was not statistically significant(P＞0.05).ConclusionThe effect ofmagnetic attachment on the restoration of elderly complete overdenture is obvious,the satisfaction rate is high,and it hurts little to periodontal health,it isworthy of clinical promotion and application. 2016 Vol. 23 (34): 110-112转116 [Abstract] ( 125 ) HTML (36 KB)  PDF  (0 KB)  ( 35 ) 113 Prelim inary clinical observation of site preservation in the removal of residual root tooth WANGWen-biao ObjectiveTo explore the influence of site preservation on alveolar bonemass.Methods 12 cases of residual root teeth underwent implant restoration from September 2012 to December 2014 in our hospital were selected as the experimental group,12 cases of residual root teeth underwent traditional restoration in the same period in our hospital were selected as the control group.The absorption level of alveolar bone of the vertical direction and the horizontal direction were measured after opevation for 3 months and 5 months in the two groups.ResultsThe absorption level of alveolar bone of the vertical direction and the horizontal direction in the experimental group was lower than that in the control group,with significant difference (P＜0.05).ConclusionThe application of site preservation in the removal of residual root teeth can reduce the absorption of alveolar bone,and the soft tissue has been increased,which can provide more soft and hard tissuemass for the patient′s follow-up implantation. 2016 Vol. 23 (34): 113-116 [Abstract] ( 103 ) HTML (39 KB)  PDF  (0 KB)  ( 37 ) 117 Effect study of Com pound Lidocaine Cream in the recovery period of general anesthesia for gastric reduction surgery LU Ting； WEIGuo-hua ；SHEN Jian ObjectiveTo explore the effect of Compound Lidocaine Cream in the recovery period of general anesthesia for gastric reduction surgery.Methods60 patients underwent selective gastric reduction surgery under general anesthesia from October 2015 to March 2016 in our hospital were selected as the research subjects,the body mass index was 35-58.5 kg/m2.All patientswere randomly divided into group L (Compound Lidocaine Cream group)and group C(the control group),30 cases in each group.The first 1/3 tracheal catheter in group L was applied with 1.0-1.5 g Compound Lidocaine Cream,while,nomedication was applied to the tracheal catheter in group C.The level ofmean arterial pressure(MAP),heart rate(HR)and oxygen saturation(SpO2)before anesthesia(T0),1 min before extubation(T1),extubation (T2),1 min after extubation(T3),3 min after extubation(T4),5 min after extubation(T5)in the two groupswere compared, the incidence rate of cough reflex,breath holding and restlessness during extubation in the two groups were recorded.ResultsThe level of MAP and HR in group C at T1-T5was higher than that at T0,with significant difference (P＜0.05). The level of SpO2in group C at T3-T5was lower than that at T0,with significant difference(P＜0.05).There was no significant difference in the level of MAP,HR and SpO2in group L between T1-T5and T0(P＞0.05).The level of MAP and HR in group L at T1-T5was lower than that in group C at T1-T5,with significant difference (P＜0.05).The level of SpO2in group L at T3-T5was higher than that in group C at T3-T5,with significant difference (P＜0.05).The incidence rate ofcough reflex,breath holding and restlessness during extubation in group L was lower than that in group C,with significant difference (P＜0.05).ConclusionApplication of Compound Lidocaine Cream applied to the outer wall of the tracheal catheter can effectively inhibit the stimulation of tracheal catheter in the recovery period of general anesthesia for gastric reduction surgery,make the patient get through the recovery and extubation period smoothly. 2016 Vol. 23 (34): 117-119 [Abstract] ( 121 ) HTML (37 KB)  PDF  (0 KB)  ( 43 ) 120 Application effect of Dexmedetom idine combined with Disposcope endoscope in elderly patientswith general anesthesia endotracheal intubation XU Chun-cheng ObjectiveTo explore the application effect of Dexmedetomidine combined with Disposcope endoscopic in elderly patients with general anesthesia endotracheal intubation.Methods80 cases of elderly patients with general anesthesia surgery in our hospital from January 2013 to December 2015 were selected and divided into the control group and the observation group by taking the digital random tablemethod,each group had 40 cases.In the operation,the control group was used direct laryngoscope in combination with sodium chloride injection,the observation group was used Dexmedetomidine combined with Disposcope endoscope.The change of the average arterial pressure and heart rate before and after intubation were compared between the two groups,and intubation time,recovery time,extubation time, once success rate of intubation and the incidence rate of pharyngeal discomfortwere compared between the two groups.ResultsThe heart rate of the control group after intubation was faster than that before intubation,and themean arterial pressure of the control group after intubation was higher than that before intubation,with significant difference(P＜0.05). Therewas no significant difference in the heart rate and average arterial pressure after and before intubation in the observation group (P＞0.05).The heart rate of the observation group after intubation was slower than that of the control group,and themean arterial pressure of the observation group after intubation was lower than that of the control group, with significant difference (P＜0.05).The intubation time,recovery time,extubation time in the observation group was shorter than that in the control group,with significant difference(P＜0.05).The success rate of intubation in the observation group was 100%,which was higher than 80%in the control group,with significant difference (P＜0.05).The incidence rate of pharyngeal discomfort in the observation group was 10%,which was lower than 28%in the control group, with significant difference (P＜0.05).ConclusionIn elderly patientswith tracheal intubation anesthesia surgery process, using the Dexmedetomidine combined with Disposcope endoscope can be effective to remain stable vital signs in the process of operation,facilitate the smooth progress of the intubation. 2016 Vol. 23 (34): 120-122转129 [Abstract] ( 132 ) HTML (37 KB)  PDF  (0 KB)  ( 30 ) 123 Application of Rifam picin Injection in treatment of tuberculosis HUANG Hua； JIANG Xin； WANGWei-hua ObjectiveTo study the application effect of Rifampicin Injection in treatment of tuberculosis(TB)to provide reference to clinical treatment of TB.Methods200 patients with TB admitted into our inpatient department of hospital from November 2015 to June 2016 were randomly divided into control group (n=100,the group was treated by 2HZE and oral Rifampicin Capsules/4HR while experimental group (n=100,the group was treated by 2HZE and intravenous drip of Rifampicin Injection/4HR of anti tuberculosis program.The sputum negative conversion rate,incidence rate of complication and financial burden between two groups were compared.ResultsAfter 1 month and 2 months treatment, the sputum negative conversion rate and the negative conversion rate of sputum smear in control group was lower than that of experimental group respectively(P＜0.05).The total incidence rate of complication in control group(32.0%)was higher than that of experimental group (9.0%),and there was a statistical difference (P＜0.05).The health economic research showed that oral Rifampicin Capsules of control group had great side effect,and medical cost was higher than that of experimental group (P＜0.05).ConclusionRifampicin Injection treating TB has significant effect,which can obviously increase sputum negative conversion rate,decrease incidence risk of complications,and reduce financial burden caused by great side effects of oral Rifampicin Capsules. 2016 Vol. 23 (34): 123-125 [Abstract] ( 132 ) HTML (33 KB)  PDF  (0 KB)  ( 29 ) 126 Clinical effect observation of oral Kangfuxin Liquid in the treatment of m ild tomoderate inflammatory bowel disease XU Jia-ke ；WANG Yun-feng ；ZHAO Jian-min ObjectiveTo observe the clinical effect of Kangfuxin Liquid in the treatment ofmild tomoderate inflammatory bowel disease.MethodsSixty patientswithmild tomoderate IBD treated in our department from June 2012 to June 2015 were randomly divided into two groups.The treatment group was treated by Kangfuxin Liquid of 10 ml every time for three times a day,at the same time,Mesalazine Sustained-Release Tablets of 1 g every time for four times a day and Compound Glutamin Entersoluble Capsules of 2 pills every time for three times a day.Control group was given Mesalazine Sustained-Release Tablets of 1 g every time for four times a day and Compound Glutamin Entersoluble Capsules 2 pills every time for three times a day.Two groups were given 4 weeks treatment as a course.After three courses of treatment,the treatment effectwas compared by reviewing the colonoscopy and the corresponding score.ResultsThe total effective ratewas 93.3%in the treatment group and 73.3%in the control group.The treatment group was significantly higher than the control group,and the difference was statistically significant(P＜0.05).The improvement of Mayo score in UC patientswas better than that of the control group (P＜0.05).The improvement of Best CDAI score in CD patientswas better than that of the control group(P＜0.05).ConclusionKangfuxin Liquid in the treatment ofmild to moderate inflammatory bowel disease has a exact therapeutic effect and it isworthy of promotion. 2016 Vol. 23 (34): 126-129 [Abstract] ( 120 ) HTML (36 KB)  PDF  (0 KB)  ( 36 ) 130 Curative effect observation of Edaravone in Parkinson disease WANG Su ObjectiveTo study the clinical effect of Edaravone treating Parkinson disease (PD)of early and late stage.Methods36 patients with treated by our hospital from April 2015 to April 2016 were selected,and they were divided into PD of early stage group(≤3.5 years)and PD of late stage group(≥4 years).Patientswere treated by Edaravone of 30 mg added into 250 ml of 0.9%sodium chloride solution to intravenously drip for 2 times every day on the basis of the routine PD treatment,and drugswere used for 2 weeks.The unified rating scale of PD(UPDRS)was used to evaluate the curative effect after treatment,incidence of complications was observed,and serum Aβ1-42and BDNF between two groups before and after treatment were detected and compared.ResultsAfter treatment,mental activity,behavior and mind,daily living activity and motor examination of the UPDRS score in PD of early stage group were significantly decreased compared with before treatment(P＜0.05),while there was no significant differences of above-mentioned indexes in PD of late stage group before and after treatment(P＞0.05).The serum Aβ1-42and BDNF of PD of early stage group after treatmentwere higher than those of PD of late stage group(P＜0.05).In 36 cases,3 cases(8.33%)had abnormal liver function,rash and other adverse reactions,but all were mild,and recovered to normal after symptomatic treatment.ConclusionEdaravone has obvious effect to improve the condition of patients with PD in early stage,but the effect is not obvious in patientswith PD in late stage. 2016 Vol. 23 (34): 130-132 [Abstract] ( 129 ) HTML (34 KB)  PDF  (0 KB)  ( 23 ) 133 Effect study of M osapride combined with Omeprazole treating gastroesophageal reflux disease ZHANG Jian-feng ObjectiveTo investigate the clinical effect of Mosapride combined with Omeprazole treating gastroesophageal reflux disease.Methods94 patients with gastroesophageal reflux disease treated in our hospital from July 2013 and July 2014 were selected and randomly divided into control group and observation group according to the time of hospitalization,and each group had 47 cases.Control group was treated by Omeprazole,while observation group was added Mosapride on the basis of treatment of control group.Treatment effect and incidence rate of adverse reaction in patientswere compared between two groups.ResultsThe total effective rate in the observation group(91.49%)was obviously higher than that of control group(70.21%),and there was a statistical difference(P＜0.05).The incidence rate of adverse reaction in observation group(4.26%)was obviously higher than that of control group(17.02%)and there was a statistical difference (P＜0.05).ConclusionThe effect of Mosapride combined with Omeprazole treating gastroesophageal reflux disease is significant,and can obviously reduce the incidence rate of adverse reaction,and it is worthy of further promotion and application in clinic. 2016 Vol. 23 (34): 133-135 [Abstract] ( 109 ) HTML (33 KB)  PDF  (0 KB)  ( 34 ) 136 A clinic study of treatment on diarrhea-predom inant irritable bowel syndrome by using integrated Traditional Chinese Medicine and W estern Medicine Therapy SUN Zhao-shuang；SUN Dan-dan ObjectiveTo explore the clinic effect of treatment on diarrhea-predominant irritable bowel syndrome(IBS) by using integrated Traditional Chinese Medicine and Western Medicine Therapy.Methods60 cases of IBS-D patients with syndrome of splenic asthenia and accumulation of dampness from Janury 2014 to December 2015 were selected, which were randomly divided into treatment group and control group,30 cases in each groups.Patients of treatment group were given Shenling Baishu Power and Institute for treatment.patients of control group were given Bifido for treatment,after 28 days,the clinical curative effectwere observated.ResultsThe symptoms scores of both the two groups after treatmentwere obviously lower than the before,the differenceswere significant(P＜0.05).After treatment,the symptoms score of the treatment group was significantly lower than that of the control group,the difference was significant(P＜0.05).The TCM symptoms curative effectof treatmentgroup was better than that of control group,after treatment,the difference was significant(P＜0.05).The total efficiency of the treatment group was 86.67%,which was higher than that of control group with 73.33%,the difference was significant(P＜0.05).No obvious adverse reaction occurred in the research.ConclusionThe therapy of combination shenling baizhu powderwith bifid triple viable capsules can obviously improve global symptoms of IBS-D,which iswith no side effect. 2016 Vol. 23 (34): 136-138 [Abstract] ( 112 ) HTML (37 KB)  PDF  (0 KB)  ( 37 ) 139 Clinical effect of Addie Injection combined with traditional Chinese medicine in the treatment of advanced gastric cancer LIN Bin bjectiveTo explore the clinical effect of Addie Injection combined with traditional Chinese medicine in the treatment of advanced gastric cancer.Methods183 cases of advanced gastric cancer in our hospital from October 2012 to February 2016 were selected,all patientswere randomly divided into three groups,61 cases in each group,group A was only given chemotherapy,the group B was used chemotherapy and Addie Injection,the group C was given oral Chinesemedicine combined with Addie Injection for treatment on the basis of chemotherapy,the results of treatment effect,adverse reaction and prognosis of the three groups were compared and analyzed statistically.ResultsPatients of three groups after treatment effect comparison showed that group A patients with KPS score improved more than 20 of the 10 cases,19 cases in group B,22 cases in group C;KPS score improved to 20 points in the 26 cases of group A,the group B of 38 cases,39 cases in group C;and the decrease of KPS score in A group was 25 cases,4 cases of group B,0 cases of group C,there were significant differenceswere significant in three groups(P＜0.05);Comparison of adverse reactions of the three groups after treatment,leucopenia patients in the group C was lower than that of other groups,the difference was significant(P＜0.01),abnormal liver function,renal dysfunction,gastrointestinal reactions,neurotoxicity and a decrease in hemoglobin and platelet decreased adverse reactions of the three groups were compared,there were no significant difference(P＞0.05).ConclusionAddie Injection combined with traditional Chinesemedicine on the treatment of patients with advanced gastric cancer ismore obvious,it can significantly improve the treatment efficiency,while reducing the status ofwhite blood cells,to stabilize the patient's condition,improve the quality of life of patients has a positive significance,it isworth to be widely used in clinical practice. 2016 Vol. 23 (34): 139-141 [Abstract] ( 125 ) HTML (33 KB)  PDF  (0 KB)  ( 31 ) 142 Analysis of prognostic influence factors in patientswith colon cancer CHEN Zhong-qi ；FENG Jian-hong； TONG Ya-qun ；ZHU Dong-yun； SONG Chu-ying ObjectiveTo study the clinical and pathological features of colon cancer,and to analyze the prognostic factors.Methods40 patients with colon cancer in our hospital from March 2012 to March 2013 were selected as the research objects,the clinical basic data,perioperative blood routine examination,biochemical examination,pathological examination resultswere reviewed.After surgery,all patientswere followed up for three years.The survival rate of patients was recorded and the possible factors influencing survival rate were analyzed by single factor analysis and multiple regression analysis.Results40 patientswith colon cancer after three years of follow-up,the disease-free survival rate was 80.0% (32/40).Single factor analysis and multiple regression analysis confirmed that the level of serum cancer embryonic antigen and the degree of pathological differentiation were independent risk factors influencing the prognosis of colon cancer patients.ConclusionThrough the analysis of the clinical pathology of colon cancer patients,it is beneficial to evaluate the prognosis of patients,strengthening the attention of high-risk patients and givingmore positive treatment, which has clinical application value. 2016 Vol. 23 (34): 142-144 [Abstract] ( 122 ) HTML (30 KB)  PDF  (0 KB)  ( 31 ) 145 Clinical app lication value of liquid thin-layer cytology and biopsy pathology in early stage of cervical cancer and cervical intraepithelial lesions YUWen-li ObjectiveTo explore the clinical application value of liquid thin-layer cytology and biopsy pathology in early stage of cervical cancer and cervical intraepithelial lesions.MethodsWomen with cervical cancer screening from January 2008 to December 2014 in our hospitalwere selected as research subjects,9000 caseswere given liquid based cytology test,891 caseswere diagnosed by biopsy pathology before operation,and the diagnosis results of the twomethodswere observed,finally,based on the final clinical diagnosis results,the diagnostic accuracy of the two methods was analyzed.Results9000 patientswho underwent liquid thin-layer cytology screening ofwomen,according to the principle of cytology and histology diagnosis could differ level,LSIL,HSIL and SCC and final pathological diagnosis coincidence rate was 31.9%(375/1174),83.8%(155/185),100.0%(65/65).91 patients who underwent biopsy pathologic diagnosis of women,CIN 1,CIN 2,CIN 3 stage,SCC and final pathological diagnosis coincidence rate was 42.8%(80/187),61.4% (285/464),71.3%(132/185),100.0%(65/65),with the increase of classification,the diagnostic accuracy was increased,and there was significant difference in the results among each group (P＜0.05).ConclusionThe combination of liquid based cytology and biopsy pathology is amethod for the diagnosis of early stage of cervical cancer and cervical intraepithelial lesions,it is beneficial to improve the diagnostic efficiency and can provide a reliable basis for early treatment. 2016 Vol. 23 (34): 145-147 [Abstract] ( 122 ) HTML (34 KB)  PDF  (0 KB)  ( 32 ) 148 Com parative analysis of three testmethods of high density protein cholesterol ZOU Shu-qin ObjectiveTo compare and analyze the accuracy and specificity of polyanionic polymer/surfactant(PPD) method and PEG-modified enzyme/sulfateα-cyclodextrin method (PEGME)and precipitationmethod in high-density lipoprotein cholesterol(HDL-C)inspection.MethodsThe known concentration 1.0 to 2.0,2.0 to 4.0 mmol/L of HDL-C, LDL-C were tested on biochemical analyzer,the parameters were analyzed by two point end method,the primary and secondary wavelength were 600 nm,700 nm,respectively,240μl R1 were joint to 3μl sample,288 s absorbance A1volume was readed out,the reaction for 5 min before the 80μl R2 added,600 s absorbance A2after reading it.valueswere calculated its content according to the reference product of HDL-C,LDL-C concentration.ResultsPPD reagent had relatively slow effect on HDL-C,nonspecific response to LDL-C was up to 10%to 20%;PEGME reagent had relatively high effect on HDL-C,the LDL-C did not have a nonspecific response,only 5%.The normal values of HDL-C,LDL-C and 1.1 to 1.7mmol/Lwere respectively Trig,1.7 to 2.9,0.4 to 1.8,and the result of PPD method was higher than that of precipitation method 7%to 15%.The reference set for precipitation results,if the serum samples in normal bilirubin concentration range,so the test results of the PPD method with false increase performance,and if the serum bilirubin concentration of＞20 mol/L,then PPD assay results had significantly lower performance,reached the reference value of 60%;the change of bilirubin concentration little interference PEGME determination results.The reference set for precipitation results,PPD determination results were influnced by the triglyceride,and was significantly improved more than 20%,while raising the concentration of triglyceride increased further pseudo PEGMEmethod;less triglyceride effect.The two were negatively correlated with triglyceride concentration.The result of PPD method was significantly higher than that of precipitationmethod (t=4.303，P＜0.05).ConclusionThe PEGMEmethod is better than PPDmethod in HDL-C inspection,the clinical laboratory should prudent application of PPDmethod,so isworthy of the clinical′s attention. 2016 Vol. 23 (34): 148-150转165 [Abstract] ( 102 ) HTML (37 KB)  PDF  (0 KB)  ( 41 ) 151 Effective measures to improve the accuracy of m icrobiological specimen exam inations LIN Li-jun ObjectiveTo explore the scientific and effectivemethods to improve the accuracy ofmicrobial specimens.MethodsAccording to the problems encountered in themicroorganism examinations in May 2014,relevant work planswere carried out including improving the quality of professionals,bettering the collection and preservation ofmicrobial specimens,and standardizing the delivery process.A comparative study of 15 000 microbial specimens collected from March 2013 to April 2014 and from May 2014 to May 2015 was conducted.ResultsThe accuracy rate (30.35%)was obviously higher than that of before implementing plan (26.49%)(P＜0.05).ConclusionMeasures like improving the quality of professionals,standardizing the collection and preservation ofmicrobial specimens,and the delivery process can obviously improve the accuracy rate of examination results ofmicrobial specimens.It should be vigorously promoted for clinical use. 2016 Vol. 23 (34): 151-153 [Abstract] ( 105 ) HTML (36 KB)  PDF  (0 KB)  ( 34 ) 154 Investigation and analysis on the status regarding the sanitation of 44 academ y socialized security canteen of a certain institution WANG Shan-yu；XU Bao-feng；XIAO Hong；YAOWei；LIQiang；CAO Yu-ting；GAO Chun-yu ObjectiveTo investigate and understand the sanitation status of the academy socialized security canteen in military institutions so as to provide reference for formulating the risk inspection,warning,control strategies and HACCP plan of food safety.MethodsFrom October 2014 to March 2015,academy socialized security canteen of a certain institution were selected as the research group.The basic saniation condition,facilities&equipments,sanitation management and quality control of food safety and so on were investigated and analyzed through the form of questionnaire and spot check,themain risk factors and the degree of influence were found.ResultsThe 44 dining hallswere undertaken by 26 catering industries with one to seven canteens undertaken for each one.Among nealy 2000 employees,the number of cook weremore than 40%,and servants accouted for 34%.The excellent and good rate of food hygiene knowledge evaluation were nearly 75%.The number of daily people weremore than 45000.The total construction area of canteen were 165 thousand and 700 cubic meters.The area ratio of canteen and operation room was 1.96∶1.00.The possessed per capita canteen area was 2.25 cumbicmeters,the operation area was 1.71 cumicmeters,which was farmore than the per captia standard of greater than or equal to 2.4 cumbic meters,and the rate of 29.55%(13/44)had complete function room with complete sanitation management system.HACCP was not eastablished in a single enterprise though having passed IS9000 quality certification.ConclusionThe hardware facilities and facility condition obtain obvious improvement regarding socialized secuity canteen ofmilitary institutions,however,the overall arrangement is still unreasonable so that standardized management standard needs to be further improved. 2016 Vol. 23 (34): 154-157 [Abstract] ( 124 ) HTML (41 KB)  PDF  (0 KB)  ( 37 ) 158 Clinical study on the regularity of syndrome elements of anorectal diseases in Quanzhou Area WANG Jian； LIXiao-ling ；WEIXiao-dan ；LUOGuan-yang； WU Rong-fa ；CHEN Hui-wen ObjectiveTo study and analyze the regularity of syndrome elements of anorectal diseases in Quanzhou Area, and to explore the clinical diagnosis and effective treatment program.Methods300 cases of anorectal diseases in our hospital from March 2015 to June 2016 were selected as the research object.According to the self-made questionnaire of traditional Chinesemedicine syndromes of the four diagnostic information collection,applying syndrome differentiation of syndrome elements,using to the frequency analysis,factor analysis and other statisticalmethods,distribution and combination regularity of syndrome elements in patientswith hemorrhoids in Quanzhou Area were researched and organized,the distribution and combination rule of the common syndrome elementswere analyzed.ResultsIrrational dietwas the main cause of the incidence of hemorrhoids in Quanzhou Area,and eating spicy food was the main reason.In the syndrome elements,the average score of the large intestine and the syndrome elements of febrile syndrome were the highest(P＜0.05).The proportion of the indexes of the large intestine damp-heat syndrome and the dampness stagnating in spleen syndrome were the largest(P＜0.05).From the essence of syndrome factor,the principal components of Z1was significantly related to the large intestine,heat and dampness,the principal components of Z2was significantly related to Qi Stagnation,Blood Stasis,the principal components of Z3was closely related to spleen,Qi Deficiency and Dampness.ConclusionThe large intestine damp-heat syndrome of syndrome elements in the Quanzhou Area is themost common syndrome elements,and large intestine is also themajor syndrome elements,Heat and Humidity are themajor syndrome elements.According to these indicators,the corresponding treatment plan can be used in the treatment of patients with hemorrhoids in Quanzhou Area,which has important significance in clinical. 2016 Vol. 23 (34): 158-161 [Abstract] ( 109 ) HTML (42 KB)  PDF  (0 KB)  ( 35 ) 162 The cross-sectional search and study of cognitive status and im p lementation of CPR among undergraduate in Northern Guangdong YUAN Jing-jiao；XU Jia-lin；JIANG Liu-huan；CHEN Yin-zhen；FANG Jun-lin；XU Jing-xiang；LIN Yi-jing ObjectiveTo understand diffuse current and implementation desire of CPR,to investigate and analyze the factors of impediment implementation and control of CPR and as to probe into the strategies of popularizing CPR.MethodsThe questionnaire was self-designed,3825 college students in two north area college from May 2015 to March 2016 were randomly selected and surveyed.ResultsTotally 3825 questionnaires were distributed,while 3487 were issued.The awareness rate of CPR in college students was 82.79%,the percentage of college students who used to study CPR was 35.33%.In the learning pathways,53.45%came from health lectures or training.In the absence of learning CPR college students,84.83%were willing to participate in training.ConclusionThe penetration rate of CPR isn′t high, just on identifying levels.butmost college student are willing to perform CPR to others and learn CPR explained by medical experts. 2016 Vol. 23 (34): 162-165 [Abstract] ( 135 ) HTML (40 KB)  PDF  (0 KB)  ( 32 ) 166 Investigation on cognitive app lication status of oral health know ledge among preschoolers parents LU Ai-yun ObjectiveTo investigate the cognitive application status of oral health knowledge among parents of preschool children.MethodsA total of 1000 preschool children parents from five kindergartens from June 2015 to June 2016 in our districtwere selected as the research group.Questionnaire survey was used to study the cognition degree of oral health knowledge of preschoolers parents,and the questionnaire survey results was analysed.ResultsThe awareness rate of parents brushing teeth before the age of 3 was 87.82%,and the awareness rate of brushing teeth in themorning and evening was 85.25%.The parents had higher cognition of oral health knowledge in these two aspects,but the cognition degree of related knowledge awareness that baby teeth was broken to treatment,pit and fissure sealant could prevent dental caries,Choosing of fluoride toothpaste were low.The frequency of preschoolers parents helping children to brush their teeth increased with the increase of academic qualifications,895 preschoolers parents acquired oral health knowledgemainly through radio and television,accounted for 55.87%,followed by the hospital publicity column,community health education,newspapers,kindergarten mission,oral hospital staff.ConclusionSome preschoolers parents have low awareness of oral health knowledge,and should further promote the propaganda of oral health knowledge of parents, which can effectively reduce the incidence of oral diseases in children and improve the children′s oral health. 2016 Vol. 23 (34): 166-168 [Abstract] ( 121 ) HTML (33 KB)  PDF  (0 KB)  ( 27 ) 169 Use condition analysis of narcotic drugs from 2013 to 2015 in our hospital LIChun-xiu ObjectiveTo investigate the utilization of narcotic drugs,and to provide reference for clinical rational drug use.MethodsNarcotic medication information were collected by the HIS from January 2013 to December 2015 in our hospital,the defined daily dose system(DDDs),the defined daily cost(DDC),serial number ratio(B/A)were calculated, and use condition of narcotic drugswas analyzed.ResultsConsumption sum and amount of narcotic drugs in our hospital from January 2013 to December 2015 were increased year by year,among Morphine Injection was rise faster and the amplitude was bigger.Pethidine Hydrochloride Injection and Fentanyl Transdermal Patcheswas decreasing year by year, which weremainly used by anesthesiology depertment,operating room,monitoring room,oncology depertment,surgery depertment.ConclusionThe use of narcotic drugs in our hospital is basically rational,which still need to further strengthenmanagement,in particular,clinical pharmacists in-depth clinical and clinicians to jointly develop individual drug regimens for anesthesia drugs,canmake clinicalmedication safer,and is able to improve the level of rational drug use. 2016 Vol. 23 (34): 169-172 [Abstract] ( 131 ) HTML (34 KB)  PDF  (0 KB)  ( 36 ) 173 Influence study ofmultidiscip linary intervention on self-management ability in patientswith chronic heart failure LICui-qiong；HU Yan-fen；CAILi-juan；XU Zhuo-fan ObjectiveTo explore the influence ofmultidisciplinary intervention on self-management ability and efficacy in patientswith chronic heart failure (CHF).Methods80 patientswith CHF in our hospital from January 2013 to December 2015 were selected and evenly divided into observation group and control group in random number table.In the control group,traditional nursingwas used,while in the observation group,themultidisciplinary intervention was conducted by the clinical pharmacists as a team.The intervention was carried out since the admission of the patients,and lasted for 6 weeksafter discharge.The scale of self-managementand Minnesota Quality of Life(QOL)Questionnaire of CHF patients were investigated and compared,the patient′s self-management ability and QOL before treatment,before discharge and 6 weeks after discharge.ResultsThere were no great differences in score of self-management ability and QOL scores in the two groups before treatment or before discharge(P＞0.05).Six weeks after discharge,the scores of self-management ability and QOL scores in the observation group were both greatly higher than those of control group,with the differences statisticant(P＜0.05).Conclusion Implementation ofmultidisciplinary intervention can effectively improve selfmanagement ability in CHF patients aswell as patient′s QOL,which isworthy of promotion and application in clinic. 2016 Vol. 23 (34): 173-175 [Abstract] ( 133 ) HTML (33 KB)  PDF  (0 KB)  ( 31 ) 176 Effect analysis of intravenous infusion of peripheral venous infusion in outpatient injection and infusion LOU Yan ObjectiveTo investigate the effect of reducing the injection rate of peripheral venous infusion in outpatient injection by using quality control circle.MethodsIn order to"reduce the infusion rate of peripheral intravenous infusion of outpatient infusion",the group of quality control circle was established from March to September 2016,the method of Brainstorming,Fishbone diagram and Platon method were used to analyze themain cause of the high rate of re injection,the changes of peripheral venous infusion rate of peripheral venous infusion in patientswere compared before and after the implementation of quality control circle.ResultsAfter the implementation of the quality control circle, the injection ratewas 4.2%,which was significantly lower than before implementation(25.7%),the difference was significant(P＜0.05).The improvement rate was 83.7%,compared with the prior to the implementation,after the implementation of quality control circle activity room transfusion puncture nurses technical level,work enthusiasm,health education ability,team to assist the ability,solve problem ability,communication ability to communicate,quality control techniqueswere improved.ConclusionQuality control circle is helpful to reduce the infusion rate of peripheral venous infusion in outpatient infusion and improve the quality of nursing,It isworthy of popularization and application. 2016 Vol. 23 (34): 176-178 [Abstract] ( 103 ) HTML (35 KB)  PDF  (0 KB)  ( 22 ) 179 Effect of com prehensive nursing intervention on medication com p liance in first-episode schizophrenic patients HU Xue-mei； CHEN Zhao； LIHua-jun ；XU Zi-ying ObjectiveTo analyze the effect of comprehensive nursing intervention onmedication compliance in patients with first-episode schizophrenia.MethodsSeventy-six patients with schizophrenia from March 2015 to March 2016 were selected and divided into two groups according to the digitalmethod,with 38 cases in each group.They were performed with different nursingmeasures as control group (basic therapy)and comprehensive nursing intervention group. The effectwas compared.ResultsThe percentage ofmedication compliance in the intervention group was 94.7%,while in the control group,the rate was 78.9%,which was displayed a statistical difference (P＜0.05).There were 4 cases recurred in the intervention group accounting for 10.5%,while in the control group,12 caseswere recurred accounting for 31.6%with a statistical difference (P＜0.01).ConclusionApplication of comprehensive nursing intervention in patients with first-episode schizophrenia obtains a significant effect in clinic.It improves themedication compliance and speeds up the return to society,which isworth promoting. 2016 Vol. 23 (34): 179-181 [Abstract] ( 132 ) HTML (34 KB)  PDF  (0 KB)  ( 32 ) 182 Effect of psychological intervention on the rehabilitation of the fam ily members of elderly patientswith cerebral vascular disease LIU Cui ；HE Li ；CENG Xiu-qun ObjectiveTo investigate the psychological state of the family members of the elderly patients with cerebral vascular disease and to take appropriate psychological nursingmeasures to the patients′rehabilitation.Methods75 cases of elderly stroke patients and their families from April 2014 to February 2016 in our hospitalwere selected and randomly divided into single intervention group and double intervention group.The patients of single intervention group were given psychological nursing intervention,the patients and their families of double intervention group were given psychological nursing intervention at the same time.The degree of satisfaction of elderly patients with cerebral vascular disease and their familymembers,the differences of psychological status,SF-36 scale score and NIHSS score of the patients before and after the intervention were compared.ResultsThe intervention satisfaction of patients and their families of the double intervention group was obviously higher than that of single intervention group,after intervention psychological conditions,SF-36 scale scores and NIHSSscore of the double intervention group were improved more significantly than the single intervention group(P＜0.05).ConclusionThe psychological status and take appropriate psychological nursing measures can influence the rehabilitation of elderly cercbrovascular parients,can effectively improve the adverse psychological state,reduce neurological function,improve the quality of life of patients and with higher,nursing satisfaction of patients and their families,it isworthy of promotion. 2016 Vol. 23 (34): 182-184 [Abstract] ( 117 ) HTML (32 KB)  PDF  (0 KB)  ( 42 ) 185 Nursing experience of M oxibustion in the treatment of epigastric pain LIHong； LIU Lan-hua ObjectiveTo explore the nursing experience of Moxibustion in the treatment of epigastric pain.Methods80 cases of stomachache patients from July 2013 to February 2015 admitted to our hospitalwere selected randomly and divided into two groups,40 cases in each group.The control group was treated with westernmedicine,the observation group was givenmoxibustion therapy combined with general nursing treatment on the basis of control group,the effect of differentmethods were compared.ResultsThe total effective rate of the observation group was 97.5%in 39 cases,after treatment,the effective rate of control group was 75.0%in 30 cases,the treatment efficiency of observation group was significantly higher than that of control group(P＜0.05).ConclusionEpigastric pain with moxibustion nursing effect and economy ismore easily accepted by the patients,it isworthy to be widely applied in clinic. 2016 Vol. 23 (34): 185-187 [Abstract] ( 109 ) HTML (32 KB)  PDF  (0 KB)  ( 38 ) 188 Analysis of the characteristics and clinical nursing of children with cough variant asthma LIYu-zheng ObjectiveTo explore the characteristics and clinical nursing of children with cough variant asthma.Methods80 children with cough variant asthma from March 2014 to June 2015 in our hospital were selected and divided into two groups.The children of the control group were treated with routine nursing and children of the observation group were treated with whole nursing.The recurrence rate,degree of satisfaction,hospitalization expense and hospital total time of two groups were compared.ResultsThe recurrence rate of cough variant asthma and the satisfaction rate in the observation group were significantly better than those of control group(P＜0.05),hospitalization expense and hospital total time of the observation group were significantly better than those of control group (P＜0.05).ConclusionThe analysis of the characteristics of children with cough variant asthma,and then the implementation of full care,not only can effectively reduce the recurrence rate of cough variant asthma,hospital costs,length of stay,but also increase the family satisfaction of children with care. 2016 Vol. 23 (34): 188-190 [Abstract] ( 116 ) HTML (31 KB)  PDF  (0 KB)  ( 25 ) 191 Application effects of high-quality nursing in the patientswith postoperative bleeding of thyrophyma KOU Yue-xia ObjectiveTo explore the application effects of high-quality nursing in the patients with postoperative bleeding of thyrophyma.Methods96 patients with postoperative bleeding of thyrophyma from March 2012 to March 2015 in our hospital were selected as the research subjects.They were divided into the control group and the observation group according to randomized double-blind method,48 cases in each group.The control group was given routine nursing care,and the observation group was given high-quality nursing care on the basis of the control group.The anxiety score,depression score,postoperative bleeding rate,rate of reoperation due to postoperative bleeding and satisfaction degree towardsnursingwere compared between the two groups.ResultsThe anxiety scorewas(21.23±0.54)scores,the score ofdepressionwas(20.65±0.57)scores,the rate ofpostoperative bleedingwas8.33%,the rate of reoperation due to postoperative bleeding was 4.17%as well as the rate of nursing satisfaction was 97.92%of the observation group patients,the anxiety score was(43.95±0.46)scores,the score of depression was(42.62±0.17)scores,the rate of postoperative bleeding was 29.17%,the rate of reoperation due to postoperative bleeding was 22.92%and the rate of nursing satisfaction was 77.08%in the control group after the nursing,two groupswere compared,the differentswere siginificant(P＜0.05).ConclusionThe high-quality nursing care in the patientswith postoperative bleeding of thyroid tumor is in significant,effectwhich isworthy of promotion and popularizing in nursing works. 2016 Vol. 23 (34): 191-193 [Abstract] ( 113 ) HTML (34 KB)  PDF  (0 KB)  ( 35 ) 194 Effect of improved method of fixed for indwelling gastric tube′s patients in department of general surgery HE Su-e； LUOMin ；ZHENG Xi-yan； CHNE Shi-zhen ；ZHOU Hong ObjectiveTo explore the application and effects of improved method of fixed for indwelling gastric tube′s patients in department of general surgery.Methods80 cases with indwelling gastric tube′s patients from November 2015 to May 2016 were selected and divided into control group (n=38)in which 3M pressure fixing tape“workers “shape fixation was applied and observation group (n=42)in which 3M tape fixation in modified fixed method were used.The incidence of nasal pressure ulcers,tapemaintaining time and gastric tube slippage rate of patients were compared in two groups.ResultsIn observation group,the incidence of nasal pressure ulcers in patients was lower than that of control group,the tape maintain a longer time and gastric tube slippage rate were significantly lower than those of control group,the differences were significant(P＜0.05).ConclusionsModified fixed with 3M pressure tape fixation of gastric tube has lower incidence of nasal pressure ulcers and prolonged duration,which reducing gastric tube slippage rate and nursing workload while patients are more comfortable.Which is worthy of being applied in patients with indwelling catheter. 2016 Vol. 23 (34): 194-196 [Abstract] ( 127 ) HTML (32 KB)  PDF  (0 KB)  ( 30 )

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