|
|
Effect of M atrine Injection on the level of pain,immune status and tumor marker in patientswith gastric cancer |
ZHU Sha |
Department of Oncology,the Second People′s Hospital ofWuxi City in Jiangsu Province,Wuxi 214000,China |
|
|
Abstract ObjectiveTo explore effect of Matrine Injection on the level of pain,immune status and tumor marker in patientswith gastric cancer.Methods48 patientswith gastric cancer in our hospital from June 2015 to April 2016 were selected as study object and divided into two groups according to the differences of treatmentmethods,24 cases in each group.Patients in control group were treated with routine treatment of gastric cancer,while patients in observation group were treated with Matrine Injection on the basis of routine treatment of control group,pain related indexes,T lymphocyte subsets indexes and tumormarkers levels of two groups before and after the treatmentwere compared.ResultsThe pain related indexes,T lymphocyte subsets indexes and tumormarkers levels of two groups before treatmentwere compared, and the difference had no statistical significance (P>0.05).The pain related indexes,T lymphocyte subsets indexes and tumormarkers levels of two groupswith the extension of time after treatmentwere continuously improved,and the levels of observation group were all better than those of control group (all P<0.05).After treatment,pain related indicators,T lymphocyte subsets and the level of tumormarkers between two groups had significant difference(P<0.05).ConclusionThe improvement role of Matrine Injection for the pain control,immunoregulation and disease treatment is active,so the comprehensive application value of Matrine Injection in the patientswith gastric cancer is higher.
|
|
|
|
|
[1] |
李雨欣,马易,孙哲.苦参碱联合胸腺五肽对胃癌放化疗大鼠免疫功能的影响[J].现代中西医结合杂志,2016,25 (18):1961-1963.
|
[2] |
张敬伟,段冬梅,任中海.复方苦参注射液与顺铂腹腔灌注化疗联合治疗胃癌恶性腹水[J].中国实验方剂学杂志,2016,22(11):179-183.
|
[3] |
?ukaszewicz-Zajac M,SzmitkowskiM,Litman-Zawadzka A,et al.Matrix Metalloproteinases and their tissue inhibitors in comparison to other inflammatory proteins in gastric cancer (GC)[J].Cancer Invest,2016,34(7):305-312.
|
[4] |
王竞,崔贵荣,霍晓辉,等.氟尿嘧啶化疗方案联合苦参注射液对晚期胃癌患者血清MMP-2、肿瘤标志物水平及S100A4水平影响研究[J].辽宁中医药大学学报,2016,18 (2):93-95.
|
[5] |
张黎.复方苦参注射液预防胃癌术后患者化疗不良反应及对免疫功能的影响[J].河北中医,2016,38(1):42-45.
|
[6] |
何仁强.复方苦参注射液联合多西紫杉醇治疗中晚期胃癌疗效分析[J].检验医学与临床,2015,12(4):552-553.
|
[7] |
罗彬.复方苦参注射液联合DCF方案治疗进展期胃癌的临床观察[J].中国当代医药,2013,20(22):66-67.
|
[8] |
Chen XZ,Zhang WH,Chen HN,et al.Associations between serum CA724 and HER2 overexpression among stageⅡ-Ⅲresectable gastric cancer patients:an observational study[J]. Oncotarget,2016,7(17):23647-23657.
|
[9] |
王浩,赵雄,朱静.热疗加化疗治疗晚期胃癌疼痛的临床应用价值[J].吉林医学,2016,37(6):1465-1466.
|
[10] |
王展梅,曹芳丽,曲琳莉,等.外周血T淋巴细胞亚群检测在胃癌病情监测及预后评价中的意义[J].癌症进展,2016,14(4):369-371.
|
[11] |
毛玲,汪顺才,陈超,等.苦参碱对人胃癌SGC-7901细胞增殖的影响及其机制[J].山东医药,2015,55(32):23-25. [12]尹莉,郑文岭,孙其喆,等.复方苦参注射液联合化疗治疗胃癌疗效的荟萃分析[J].中国实验方剂学杂志,2013,19(14):325-330.
|
[13] |
黄俊婷.苦参素注射液对晚期胃癌TP方案化疗的免疫调节作用[J].中国卫生产业,2014,11(8):137-138.
|
[14] |
汪顺才,毛玲,梁靓,等.苦参碱联合卡铂对人胃癌SGC-7901细胞增殖及凋亡的影响[J].中国医药科学,2015,5 (23):35-38.
|
[15] |
佘玉清,陈昱倩,颜延凤,等.不同浓度苦参碱、大蒜素对人胃癌细胞株MKN-45杀伤作用的实验研究[J].江苏中医药,2014,46(11):82-83.
|
|
|
|