戈舍瑞林联合曼月乐治疗子宫腺肌病的效果评价

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Abstract ObjectiveTo study the efficacy of goserelin combined with Mirena in the treatment of adenomyosis.MethodsSeventy patientswith adenomyosis treated in the gynaecology department of our hospital from February 2014 to February 2015 were randomly divided into control group and observation group,with 37 cases in each group.The control group was treated with Goserelin,observation group was treated with Goserelin combined with Mirena.The treatment effect,indicators of uterine,dysmenorrhea and situation ofmenstruation of patients were compared between the two groups;the adverse reactions of two groups were observed.ResultsThe effective rate of the observation group was 94.29%,significantly higher than that of the control group(85.71%),the difference was statistically significant(P＜0.05).After treatment, the uterine volume and endometrial thickness of the observation group were significantly less than those of the control group,the differences were statistically significant(P＜0.05);the VAS pain score and PBACmenstrual volume score in the observation group were significantly lower than those in the control group,the difference was statistically significant (P＜0.05);the total incidence of adverse reactions,such as fatigue,osteodynia,climacteric symptoms,irritability,irregular vaginal bleeding,breast pain of the two groups had no statistically significant difference(P＞0.05).ConclusionGoserelin combined with Mirena has significant effect in the treatment of adenomyosis,can directly effect on uterine lesions,inhibit abnormal growth of endometrial,reduce disease activity,improve clinical symptoms,avoid the surgery effectively,has positive clinical significance.

Key words： Adenomyosis Goserelin Mirena Therapeutic evaluation

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	Articles by authors
	WU Yi-xue
	ZHONG Jian-ye
	YANG Xiu-yun

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WU Yi-xue,ZHONG Jian-ye,YANG Xiu-yun. Effectiveness evaluation of Goserelin combined with Mirena in the treatment of adenom yosis[J]. 中国当代医药, 2016, 23(34): 95-97.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I34/95

[1]	李巧云，刘秀荣，冯玉珍.亮丙瑞林联合曼月乐治疗子宫腺肌病49例[J].中国药业，2015，24（5）：85-86.
[2]	蓝莹，肖慧莲.醋酸亮丙瑞林缓释微球联合曼月乐环治疗子宫腺肌症42例临床观察[J].中国民族民间医药，2015，24（22）：86.
[3]	桂琦，刘洋，孙春意，等.曼月乐环治疗子宫腺肌病75例临床观察[J].昆明医科大学学报，2015，36（5）：115-117.
[4]	谭红.曼月乐治疗子宫腺肌病的临床疗效[D].苏州：苏州大学，2015.
[5]	郭祥翠，王倩青，宋艳品.腹腔镜保守手术联合戈舍瑞林治疗Ⅲ/Ⅳ期子宫内膜异位症疗效分析[J].中国妇幼保健，2014，29（3）：468-470.
[6]	宋菁华，鲁桦，张军，等.腹腔镜手术联合促性腺激素释放激素激动剂治疗内异症的临床研究[J].中华妇产科杂志，2013，48（8）：584-588.
[7]	赵菁.“曼月乐”联合MURU治疗子宫腺肌病的临床研究[D].遵义：遵义医学院，2014.
[8]	邵永红，王芸.散结镇痛胶囊联合曼月乐治疗子宫腺肌病临床效果及安全性评价[J].实用药物与临床，2013，16（11）：1038-1041.
[9]	曹月琴.亮丙瑞林联合曼月乐治疗子宫腺肌症40例临床观察[J].中外女性健康研究，2016，（13）：187-188.
[10]	李锦行，刘红，张萍.腹腔镜下子宫腺肌病病灶切除术联合促性腺激素释放激素激动剂治疗子宫腺肌病的疗效观察[J].现代妇产科进展，2015，24（10）：743-746.
[11]	竺鹏飞，尧良清.腹腔镜保守性手术联合戈舍瑞林治疗重度卵巢内膜异位症的临床研究[J].中国妇幼保健，2015，30（21）：3737-3739.
[12]	王曼丽，王韦.内异消方联合保守手术及戈舍瑞林治疗子宫内膜异位症疗效研究[J].中华中医药学刊，2016，34 （6）：1354-1356.
[13]	耿丹.腹腔镜术后结合注射用醋酸戈舍瑞林治疗子宫内膜异位症的效果探析[J].中国现代药物应用，2016，10（15）：150-151.
[14]	彭艳，姚吉龙，刘剀，等.促性腺激素释放激素激动剂联合曼月乐治疗保守性手术后中重度子宫内膜异位症的疗效分析[J].生殖与避孕，2013，33（7）：491-493.
[15]	黄玥，张蔚，王勇，等.腹腔镜手术联合促性腺激素释放激素激动剂治疗子宫内膜异位症的Meta分析[J].中华实用诊断与治疗杂志，2015，29（3）：270-274.