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2018 Vol. 25, No. 5
Published: 2018-02-18
 
 
4 Influence of cigarette smoke extract on myostatin and inflammatory mediators in mouse C2C12 cells
LI Yu-ji;ZHOU Xu;PEI Xing-hua; HUANG Li;LEI Yan-jun; ZHANG Lu-lu
ObjectiveTo investigate the effect of cigarette smoke extract on myostatin and inflammatory mediators in mouse C2C12 cells.MethodsDifferent concentrations of CSE and/or myostatin-siRNA stimulated or interference mouse C2C12 cells,and then detected influence of CSE on cell growth by MTT,according to the different treatment methods,the experimental research objects were divided into the control group,5%CSE group,the myostatin-siRNA group,5%CSE＋myostatin-siRNA group.Real-time PCR was used to detect the expression of myostatin mRNA,Western blot was used to detect expression of myostatin protein,ELISA was used to detected tumor necrosis factor alpha (TNF-alpha)and interleukin 8(IL-8)level in cell culture medium.ResultsThe CSE at the concentration above 5%could significantly inhibit the proliferation of C2C12 cells in mice(P＜0.05).The expression of myostatin mRNA and protein in C2C12 cells treated with 5%CSE was significantly higher than that of the control group after 48 h(P＜0.05).The content of IL-8 and TNF-alpha in the cell culture fluid was significantly higher than that in the control group (P＜0.05).After siRNA interfered with myostatin,the mouse C2C12 cells were treated with CSE,the content of IL-8 and TNF-alpha in cell culture solution was significantly lower than that in CSE treatment group(P＜0.05).ConclusionCSE can up-regulate the expression of myostatin and increase inflammatory mediators releasing from C2C12 cells.
2018 Vol. 25 (5): 4-7 [Abstract] ( 200 ) HTML (34 KB)  PDF  (0 KB)  ( 73 )
8 Expression and clinical significance of Gab2 in cervical cancer tissue
ZHANG Yan ;CHENG Long;DUAN Wen-li;LIU Xiao;ZHOU Hang
ObjectiveTo investigate the correlation between the expression of Gab2 in cervical cancer tissue and the clinical pathological features.Methods80 cervical cancer specimens definitely diagnosed by pathology from January 2012 to December 2013 and 20 normal cervical tissue specimens which were stored in our Department of Pathology were randomly selected in our hospital.The immunohistochemical method was used to detect the expression of Gab2 in cervical cancer tissues and normal cervical tissues,and was statistically analyzed together with the clinical and pathological data.ResultsThe positive expression rate of Gab2 in 80 cervical cancer tissues was 58.75% (47/80),and in the 20 normal cervical tissues,only 3 cases were presented with weak positive expression.The rate of positive expression was 0%,which was displayed a statistical difference (P＜0.05).The expression level of Gab2 protein in cervical cancer tissues was positively correlated with lymph node metastasis(P＜0.05),but didn’t present with great correlation with age,size of tumor,histological grading or FIGO stage(P＞0.05).The recurrence and metastasis rate in patients with high Gab2 expression was significantly higher than that of low expression of Gab2(P=0.001).ConclusionGab2 may play an important role in the occurrence and progression of cervical cancer,and may be considered as a potential for prognostic marker of cervical cancer.
2018 Vol. 25 (5): 8-10 [Abstract] ( 198 ) HTML (27 KB)  PDF  (0 KB)  ( 46 )
11 Reproducibility of diffusional kurtosis imaging measurement in uterine cervical carcinoma
ZHENG Xiang;CHEN Yun-bin;CHEN Wen-juan;CHEN Wei-bo
ObjectiveTo evaluate the reproducibility of magnetic resonance imaging (MRI)diffusional kurtosis imaging(DKI)in detecting of cervical carcinoma.Methods10 patients and 10 healthy volunteers in our hospital from June to December in 2016 were selected and underwent duplicate MRI scans by using DKI with an interval of 24 hours to 14 days.The metric K and D were obtained from parametric maps and evaluated by statistical software SPSS 19.0.ResultsThe D value of intra group variation coefficient(ICC)of the total subjects,volunteers,and cervical cancer patients were 0.899,0.935 and 0.828,respectively.The ICC of parameter K was 0.870,0.871 and 0.877,respectively.The coefficients of variation of the D in the total subjects,the volunteers and the patients with cervical cancer were 17.23%,16.43%and 16.51%,respectively.The coefficients of variation of parameter K were 17.85%,20.16%and 12.28%,respectively.ConclusionDK imaging sequence appears reproducible in detecting the non Gauss diffusion of water molecules in cervical carcinoma.
2018 Vol. 25 (5): 11-14 [Abstract] ( 191 ) HTML (29 KB)  PDF  (0 KB)  ( 82 )
15 Effect of Paroxetine combined with Shenqiwuweizi Granule in the treatment of generalized anxiety disorder
YAO Xu-dong; LIU Fang
ObjectiveTo investigate the effect of Paroxetine combined with Shenqiwuweizi Granules in the treatment of generalized anxiety disorder(GAD).Methods78 cases of GAD patients treated in our hospital from March 2016 to July 2017 were randomly divided into the study group and the control group,with 39 cases in each group.The control group patients were given the Paroxetine treatment,the study group patients were treated with Shenqiwuweizi Granule on the basis of the control group.The clinical curative effect,the change of Hamilton Anxiety Scale (HAMA)score and the Pittsburgh sleep quality index(PSQI)before and after treatment,the incidence of adverse drug reactions were compared between the two groups.ResultsThe total effective rate of clinical treatment was 97.4%after 8 weeks of treatment in the study group,which was significantly higher than that of the control group of 82.1%(P＜0.05).There was no significant difference in the HAMA score and PSQI score before the treatment between the two groups(P＞0.05).The HAMA score and PSQI score of the study group decreased significantly at the 1 week after treatment,and the control group began to decrease from the second week after the treatment.The scores of HAMA and PSQI in the study group were significantly lower than those in the control group (P＜0.05).There was no statistical difference in the TESS score between the two groups of patients after treatment at different time points(P＞0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).ConclusionOn the basis of Paroxetine treatment of GAD,the combination of Shenqiwuweizi Granule can relieve anxiety and depression,and improve the treatment effect,the safety is high,patients will not produce drug dependence,it is worthy of clinical promotion and application.
2018 Vol. 25 (5): 15-17 [Abstract] ( 254 ) HTML (28 KB)  PDF  (0 KB)  ( 78 )
18 Influence of bone marrow mesenchymal stem cells on lung ischemiareperfusion injury in mice
SUN Chang-rong;HOU Nian-guo;LI Hui;SHUAI Xun-jun;SUN Ming-jie;TANG Yu-ru;XU Tang-wen;AI Deng-bin
ObjectiveTo investigate the influence of bone marrow mesenchymal stem cells(BMSCs)on lung ischemiareperfusion injury(LIRI)in mice.MethodsBMSCs from rats were isolated,cultured and purified by the whole bone marrow acherence method.LIRI was produced by occlusion of the left hilum of lungs for 60 min followed by 240 min reperfusion.70 mice were randomly divided into 7 groups(n=10),included the sham operation group(the Sham group),the ischemia-reperfusion group(the I/R group),the BMSCs 1 group(tail vein injections of 1×106BMSCs),the BMSCs 2 group(tail vein injections of 2×106BMSCs),the BMSCs 5 group(tail vein injection of 5×106BMSCs),the BMSCs 10 group(tail vein injection of 10×106BMSCs),the BMSCs it group(endotracheal injection of 5×106BMSCs).At the end of reperfusion,blood samples were obtained for blood gas analysis and PaO2/FiO2was calculated.Then,the animals were sacrificed and lung tissues were immediately removed for determination of superoxide dismutase(SOD),tumor necrosis factor-α(TNF-α),interleukin-8 (IL-8),and myeloperoxidase (MPO)and for microscopic examination of the pathological changes of lungs which were scored.ResultsCompared with Sham group,PaO2/FiO2was significantly decreased,the pathological scores and the levels of TNF-α,IL-8,and MPO were increased,and SOD activity was decreased in I/R,BMSCs 1,BMSCs 2,BMSCs 5,BMSCs 10,BMSCs it group,the difference was statistically significant (P＜0.05).Compared with I/R group,PaO2/FiO2was significantly increased,the pathological scores and the levels of TNF-α,IL-8,and MPO in lung tissues were decreased,and SOD activity was increased in BMSCs 1,BMSCs 2,BMSCs 5,BMSCs 10,BMSCs it group,the difference was statistically significant(P＜0.05).The most obvious group is BMSCs 10,the difference was statistically significant(P＜0.05).There is no obvious difference between endotracheal injection and intravascular injection with the same concentration of BMSCs,the difference was not statistically significant(P＞0.05).ConclusionBMCS can alleviate LIRI in mice,and the responsible mechanism is related to inhibition of inflammatory responses.The lung protective effect is dose dependent.There is no significant difference between endotracheal injection and intravascular injection with the same concentration of BMSCs.
2018 Vol. 25 (5): 18-21 [Abstract] ( 211 ) HTML (36 KB)  PDF  (0 KB)  ( 100 )
22 Influence of traditional Chinese medicine fumigation combined with Nitroglycerin Ointment on postoperative pain and sleep quality in anal fissure patients
LI Jue； LIANG Ya
ObjectiveTo evaluate the influence of traditional Chinese medicine fumigation combined with Nitroglycerin Ointment on postoperative pain and sleep quality in anal fissure patients.MethodsFrom January 2016 to June 2017,112 cases of postoperative patient with anal fissure treated in our hospital were selected as the research subjects,and there were divided into the control group(n=56)and the observation group(n=56)by random number table method.The control group was treated with traditional Chinese medicine fumigation treatment,and the observation group was treated with traditional Chinese medicine fumigation combined with Nitroglycerin Ointment treatment,respectively.The pain and sleep quality of the two groups were evaluated at 1stday,4thday,and 7thday after operation.The adverse events were compared between the two groups.ResultsThere was no statistical significance in pain and sleep quality score between the 2 groups at 1stday (P＞0.05).The pain and sleep quality of the two groups were significantly improved at 4th,7thday,and the observation group improved more obviously,with statistical significance(P＜0.05).There was no statistical significance in the incidence of headache between the two groups(P＞0.05).The incidence of complications in the observation group was significantly lower than that in the control group,with statistical significance(P＜0.05).ConclusionTraditional Chinese medicine fumigation combined with Nitroglycerin Ointment treatment can effectively relieve postoperative pain in anal fissure patients and improve the quality of sleep at night,and reduce the incidence of complications.
2018 Vol. 25 (5): 22-24转31 [Abstract] ( 226 ) HTML (32 KB)  PDF  (0 KB)  ( 41 )
25 Effect of intraoperative hypothermia on surgical patients and research progress of nursing measures
Li Lian-ying
This article reviews the effect of hypothermia on the operation patients and nursing care,in the operation of the targeted selection of reasonable thermal measures,and the implementation of psychological care,in order to maintain the relative constant temperature of patients during the operation,to ensure the safety of patients,reduce various adverse reactions,save medical resources.
2018 Vol. 25 (5): 25-27 [Abstract] ( 193 ) HTML (27 KB)  PDF  (0 KB)  ( 80 )
28 The current status of Helicobacter pylori infection and the progress of clinical treatment
OU Ting-Hong；XIANG Ping；ZHOU Wei-Hua
Helicobacter pylori(Hp)infection is the main pathogenic factor of chronic gastritis,peptic ulcer,gastric cancer and other digestive tract diseases.Eradication of Hp can promote ulcer healing and prevent recurrence and complications of peptic ulcer.While reduce that incidence of gastric cancer.Hp infection rate is high and antibiotic resistance rate is increasing in China.How to choose an effective,economical and low-adverse-reaction regimen to eradicate HP is a problem that every clinician must face.
 
2018 Vol. 25 (5): 28-31 [Abstract] ( 207 ) HTML (32 KB)  PDF  (0 KB)  ( 45 )
32 Influence of washed red blood cells on blood transfusion effect in patients with multiple red blood cells transfusion
WANG Yan-chun
ObjectiveTo investigate clinical effect of washed red blood cells(WRBC)transfusion in patients with multiple red blood cells transfusion.Methods134 cases of patients with multiple red blood cells transfusion from June 2015 to June 2017 were randomly divided into control group and research group,67 cases in each group,and leukocyte-depleted red blood cells(LDRC)were transfused in control group,and WRBC was transfused in research group.And transfusion effect and adverse reaction were tested between control group and research group.ResultsLevels of Hb,RBC,WBC and PLT were no significant difference before blood transfusion between the two groups(P＞0.05).The level of Hb and RBC after transfusion were higher than those before transfusion in every group (P<0.05),and level of Hb and RBC in research group were higher than that in control group after transfusion(P<0.05).Increasing of Hb and RBC was higher in research group than that in control group(P<0.05),WBC and PLT count had no significant difference between the two groups before and after blood transfusion(P＞0.05),effective rate of blood transfusion was 98.5%in research group than 85.4%in control group,and effective rate of blood transfusion was higher in research groups than that in control groups(P<0.05),incidence rate of adverse transfusion reactions was no significant difference in two groups (P＞0.05).ConclusionWRBC can improve effect of red blood cells transfusion in patients with repeated blood transfusion,and improve efficiency of blood transfusion.
2018 Vol. 25 (5): 32-34 [Abstract] ( 180 ) HTML (25 KB)  PDF  (0 KB)  ( 89 )
35 Analysis of clinical effect of open reduction and internal fixation of lower tibiofibula plus separation and fixation in the treatment of ankle fracture
ZHANG Ze ;JIN Yun-long
ObjectiveTo investigate the clinical effect of open reduction and internal fixation of lower tibiofibula plus separation and fixation in the treatment of ankle fracture.MethodsAltogether 94 patients with ankle fracture who were treated in our hospital from February 2015 to August 2016 were selected as the object of this research and randomly divided into control group(without fixed screws)and observation group(with fixed screws),47 cases in each group.The clinical efficacy,tibiofibular clear space(TBCS)and tibiofibular overlap(TBOL)at different post-operative periods,postoperative TBCS,TBOL,ankle function score and patients′satisfaction were compared between the two groups.ResultsThe total effective rate of observation group was 93.62%versus 68.08%in the control group,with statistically significant difference between two groups(χ2=9.8947,P<0.05);X-ray examination showed that the TBCS and TBOL of two groups at post-operative 1 and 12 months were significantly improved in comparison with those before operation，without statistically significant difference (P＞0.05);TBOL at different post-operative periods had statistically significant difference between two groups(P<0.05);TBCS at post-operative 1 month had no statistically significant difference between two groups(P＞0.05);TBCS at post-operative 12 months were significant difference between two groups(P<0.05).The post-operative TBCS,TBOL and ankle function scores of observation group were(3.49±0.23)mm,(8.55±0.18)mm and(89.7±6.7)points versus(3.62±0.39)mm,(8.15±0.23)mm and(80.3±4.9)points in the control group,with statistically significant difference between two groups （P<0.05）.The patients′satisfaction rate of the observation group was 97.87%,significantly higher than that of the control group(82.98%),with statistically significant difference between the two groups(P<0.05).ConclusionOpen reduction and internal fixation of lower tibiofibula plus separation and fixation in the treatment of ankle fracture is beneficial to the reduction of articular surface,better treatment of cartilage and ligament injury,and improves the effect of clinical operations,which is worthy of clinical application.
2018 Vol. 25 (5): 35-37 [Abstract] ( 237 ) HTML (28 KB)  PDF  (0 KB)  ( 73 )
38 The application value of APC level for the prognosis assessment of patients with severe pneumonia
MU Wei-feng ；DONG Mao-xuan
ObjectiveTo observe the level of serum activated protein C(APC)in patients with severe pneumonia and evaluate its value in evaluating the prognosis of patients with severe pneumonia.MethodsA total of 54 patients with severe pneumonia were selected from October 2013 to July 2016,the prognosis was divided into survival group(n=30)and death group(n=24).30 patients with non-severe pneumonia were selected randomly in the same period,as a non-severe pneumonia group.A healthy group of 30 healthy people were selected in our hospital during the same period.Using enzyme-linked immunosorbent method to detect each group APC level in the serum.ResultsThe APC level of the pneumonia group was(330.81±72.80)ng/ml,which was lower than that the healthy group[(436.57±62.69)ng/ml],and the difference was statistically significant(P<0.05).The APC level of the severe pneumonia group was(296.60±58.26)ng/ml,which was lower than that the non-severe pneumonia group [(392.38±552)ng/ml],and the difference was statistically significant(P<0.05).The APC level of the death group was(263.89±53.53)ng/ml,which was lower than that the survival group [(322.75±48.34)ng/ml],and the difference was statistically significant(P<0.05).ConclusionLevel of APC in serum is associated with pneumonia,and the level of APC reflects the severity of the disease and is related to the prognosis of severe pneumonia.The lower the APC level,the worse the prognosis of the patients.
2018 Vol. 25 (5): 38-40 [Abstract] ( 195 ) HTML (27 KB)  PDF  (0 KB)  ( 81 )
41 Clinical effect of Insulin pump as an intensive therapy in patients with type 2 diabetes mellitus and its influence on blood glucose fluctuation
WEI Shu-xiang; FANG Yong-hong; LU Jie-can
ObjectiveTo comprehensively analyze the clinical effect of intensive Insulin pump therapy in patients with type 2 diabetes mellitus and its influence on blood glucose fluctuation.MethodsA total of 80 patients with type 2 diabetes treated in our hospital from July 2015 to July 2017 were selected as the subjects,and randomly divided into experimental group(short-term intensive Insulin pump therapy)and control group(routine subcutaneous injection of Insulin),40 cases in each group.The standard deviation of blood glucose before and after treatment,the average range of blood glucose fluctuation,the glycosylated hemoglobin,Insulin resistance index,the time of blood glucose reaching the standard,and the dose of Insulin on reaching the standard were analyzed.ResultsBefore treatment,the standard deviation of blood glucose and average blood glucose fluctuation in the two groups were not statistically significant(P>0.05).After therapy,the standard deviation and the average range of blood glucose fluctuation were significantly lower in the experimental group than that in the control group,the difference was statistically significant(P<0.05).In the experimental group,the time of blood glucose reaching the standard was significantly shorter compared with that in the control group,the difference was statistically significant(P<0.05).The Insulin dose in the experimental group was significantly less than that in the control group,the difference was statistically significant (P<0.05).The glycosylated hemoglobin and Insulin resistance index in the experimental group were greatly lower in comparison of those in the control group,the difference was statistically significant(P<0.05).ConclusionThe clinical effect of intensive Insulin pump therapy in patients with type 2 diabetes mellitus is remarkable.
2018 Vol. 25 (5): 41-43 [Abstract] ( 203 ) HTML (25 KB)  PDF  (0 KB)  ( 68 )
44 Comparison of clinical efficacy of Liraglutide and Insulin pump in newly diagnosed obese patients with type 2 diabetes mellitus
ZHAO Sa ;SHI Yi-shan
ObjectiveTo compare the efficacy of Liraglutide and continuous subcutaneous Insulin infusion (CSII)via pump in newly diagnosed obese patients with type 2 diabetes mellitus.MethodsFrom October 2015 to October 2016,a total of 64 patients with newly-diagnosed type 2 diabetes mellitus（DM）without application of antidiabetic drugs treated in our department were randomly divided into Liraglutide hypodermic injection group and continuous Insulin pump group.The treatment was lasted for 4 weeks.The fasting and 2-hour postprandial blood glucose,Insulin level in fasting,glycosylated hemoglobin(HbA1c),body mass index(BMI),and waist circumference were compared before and after treatment between the two groups.ResultsThe fasting plasma glucose(FPG),2-hour postprandial blood glucose(2 h PG),fasting Insulin (FINS),and HbA1c were significantly improved in the two groups compared with those before treatment,but there was no significant difference in inter-group comparisons.The BMI and waist circumference in Liraglutide group were obviously improved compared with those before treatment,and also displayed statistical differences in comparison of Insulin pump group.ConclusionFor the newly diagnosed obese patients with type 2 diabetes,the application of Liraglutide for blood glucose reduction can effectively reduce the blood glucose level,improve the function of islet β cells,and the effect is tantamount to that by Insulin pump.The former has the advantages of reducing body weight and waist circumference.
2018 Vol. 25 (5): 44-46 [Abstract] ( 232 ) HTML (24 KB)  PDF  (0 KB)  ( 94 )
47 Study on distribution characteristics of upper extremities affected by diabetic peripheral nerve injury
HE Hui;LUO Zhi-hong;DENG Hong-wei
ObjectiveTo investigate the distribution characteristics of upper extremities affected by diabetic peripheral nerve injury.Methods300 patients with diabetes treated in our hospital from March 2016 to May 2017 were selected and their data were analyzed.150 patients with diabetic peripheral neuropathy were selected as the observation group.150 diabetic patients without peripheral neuropathy were selected as the control group.All patients were examined by electromyography/evoked potentiometry for the detection of sensory nerve conduction velocity(SCV),sensory nerve conduction amplitude(SNAP),motor nerve conduction velocity(MCV),compound muscle action potential amplitude(CAMP)in the median nerve,radial nerve and ulnar nerve of upper extremities.The nerve conduction parameters were compared between the two groups.ResultsThe SCV and MCV of median nerve,radial nerve and ulnar nerve in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).Different nerves were compared,the abnormal rates of median nerve,motor nerve and sensory nerve were higher than those of other nerves(P<0.05).There was no significant difference in the abnormal rates of sensory nerve and motor nerve between the ulnar nerve and radial nerve (P>0.05).The sensory nerve,motor nerve,and median nerve were compared,and the abnormal rate of sensory nerve was higher than that of motor nerve,the difference was statistically significant(P<0.05).There was no significant difference in the abnormal rate of sensory nerve and motor nerve between the ulnar nerve and radial nerve (P>0.05).ConclusionThe nerve conduction in the patients with diabetic peripheral neuropathy is significantly lower than that in the diabetic patients without peripheral neuropathy,and compared with the diabetic patients without peripheral neuropathy,the affected nerve of upper extremities and the affected median nerve are also the more severe.
2018 Vol. 25 (5): 47-49 [Abstract] ( 200 ) HTML (24 KB)  PDF  (0 KB)  ( 98 )
50 Impact of general practitioner team intervention on the management of community diabetic patients
ZOU Guo-tao; LUO Min-shan; WU Yuan-yuan
ObjectiveTo explore the influence of general practitioner team intervention on the management of diabetic patients in the community.MethodsFrom March 2015 to December 2016,94 patients with diabetes in our center were selected as the research objects,and divided into control group and observation group by random number tables method,47 cases in each group.In the control group,the traditional diabetes community management mode was used,while in the observation group,general practitioner team intervention was provided.The quality of life and diabetic control in the two groups were observed and compared.ResultsIn the observation group,the scores of psychological function,physiologicalfunction,spiritualballast,socialfunction,and surroundings in QOL-100 scale were all higher than those in the control group,the difference was statistically significant(P<0.05).The scores of cognition on diabetes and its complications,livinghabit,treatment,survial skills,therapeutic goal,and knowledge structure in the observation group were higher than those in the control group,the difference was statistically significant(P<0.05).ConclusionGeneral practitioner team intervention mode plays an important role in the management of community diabetes patients,can effectively improve the quality of life and physical function of patients,maintain the stability of patients,which is worthy of wide promotion.
2018 Vol. 25 (5): 50-52 [Abstract] ( 197 ) HTML (26 KB)  PDF  (0 KB)  ( 116 )
53 Analysis on the clinical effect of different routes of medication in the treatment of missed abortion
HUANG Jian-xiong ;LI Li-jun; CHI Hui-juan
ObjectiveEvaluation of clinical effect of Misoprostol on different routes of medication in the treatment of missed abortion.Methods80 cases of patients with missed abortion from putian college affiliated hospital from January 2015 to June 2016 were selected as the subjects,and randomly divided into the experimental group and the control group,40 cases in each group.The test group received150 mg oral Mifepristone combined with Misoprostol 0.6 mg plug vagina.The control group received 150 mg oral Mifepristone combined with Misoprostol 0.6 mg oral.The uterine contraction time,time of discharge of embryo after taking medicine,the amount of bleeding and the rate of complete abortion after 2 hours between the two groups were observed and compared.ResultsIn the experimental group,the time of uterine contraction and the discharge time were significantly less than those in the control group,the difference was statistically significant(P<0.05).The amount of bleeding in the experimental group was significiantly less than that in the control group after 2 h,the difference was statistically significant(P<0.05).The complete abortion rate was 20.0%in the test group,higher than 5.0%in the control group,the difference was statistically significant(P<0.05).ConclusionMifepristone combined Misoprostol plug vagina for missed abortion has better clinical efficacy than Mifepristone combined Misoprostol oral,which has the lower rate of embryos after discharge.
2018 Vol. 25 (5): 53-55 [Abstract] ( 192 ) HTML (26 KB)  PDF  (0 KB)  ( 95 )
56 Impact assessment of contraceptive counseling and education after abortion on women′s contraceptive behavior
DENG Yu-ao; LI Xiu-yun
ObjectiveTo explore the application effect of contraceptive counseling and education service adding in the service of patients after abortion,and to discuss the clinical application value.MethodsFrom March 2016 to February 2017,500 abortion patients treated in our hospital were enrolled as research object.According to the odd/even number,they were evenly divided into the control group and the experimental group,250 cases in each group.In the control group,conventional therapy was used,while in the experimental group,contraceptive counseling and education on the basis of the conventional treatment was added.The repeated abortion rate after therapy scores of self-rating depression scale SDS and self-rating anxiety scale was compared.ResultsIn the experimental group,the rate of repeated abortion was 0.80%,which was significantly lower than 8.40%in the control group,the difference was statistically significant(P<0.05).The and SAS in the experimental group were much lower than those in the control group,the difference was statistically significant(P<0.05).ConclusionContraceptive counseling and education for patients after abortion is helpful to improve the psychological quality,appease the negative emotions,and increase service satisfaction.Meanwhile,it can improve patient′s contraceptive awareness and decrease the repeated abortion rate,and play great role in clinic,which is worthy of clinical application and promotion.
2018 Vol. 25 (5): 56-58 [Abstract] ( 213 ) HTML (26 KB)  PDF  (0 KB)  ( 100 )
59 Effect of reproductive prognosis in infertile patients caused by intrauterine factors after hysteroscopic treatment
ZHANG Yao-yao;ZHONG Gong-le
ObjectiveTo investigate the effect of reproductive prognosis in infertility caused by intrauterine factors.Methods46 cases of infertility caused by intrauterine factors treated in our hospital from January 2016 to January 2017 were selected as the subjects.The operation for the above patients was performed under the assistance of hysteroscopy.The proportion of intrauterine factors in patients with hysteroscopy before and after treatment was recorded,and the prognosis of the patients was evaluated.ResultsThe proportion of endometrial polyps,polypoid hyperplasia and intrauterine adhesions in patients after treatment was significantly lower than that before treatment,the difference was statistically significant(P<0.05).In 46 cases of patients,the pregnancy rate was 73.9%,the abortion rate was 20.0%,the preterm birth rate or the pregnancy rate was 6.5%.ConclusionHysteroscopy assisted surgery for infertility caused by intrauterine factors,can significantly improve the patient′s pregnancy outcome,enhance the patient′s reproductive prognosis,which is worthy of further promotion in clinical research.
2018 Vol. 25 (5): 59-61 [Abstract] ( 178 ) HTML (23 KB)  PDF  (0 KB)  ( 83 )
62 Value analysis of color doppler ultrasound and ultrasound guided biopsy in breast cancer patients
TIAN Ai-hong; XU Jia-liang; CHEN Shu-rong; YANG Ya-li;DENG Jing-xian; LIU Jin
ObjectiveTo study the value of color doppler ultrasound and ultrasound guided biopsy in breast cancer patients.MethodsFrom January 2015 to May 2017,the clinical data of 70 patients with breast tumor in our hospital were selected and divided into benign breast tumor group and breast cancer group according to postoperative pathological findings.The results of color doppler ultrasound examination and ultrasound guided biopsy,and postoperative pathological results were compared between the two groups.ResultsThere was a statistical difference in two-dimensional ultrasound images between the benign breast tumor group and breast cancer group(P<0.05).The blood flow parameters,blood flow velocity and blood flow resistance index by color doppler were displayed statistical significance between the two groups (P<0.05).The diagnostic accurate rate based on the results from ultrasound guided puncture biopsy on breast cancer was 98.39% (61/62).No severe complications occurred after puncture.ConclusionApplication of color doppler ultrasound and ultrasound-guided biopsy for the diagnosis of breast tumors are highly consistent with that by postoperative pathological diagnosis,which can be promoted in clinical practice.
2018 Vol. 25 (5): 62-64 [Abstract] ( 204 ) HTML (24 KB)  PDF  (0 KB)  ( 104 )
65 Effect observation of drug combination de-escalation in the treatment of acute attack of wheezing in infants
CHEN Ai-qing ;ZHANG Jun-ling
ObjectiveTo observe the clinical effect of drug combination de-escalation in the treatment of acute attack of wheezing in infants.MethodsFrom February 2015 to February 2017,103 infants with acute attack of wheezing in outpatient department of pediatrics in our center were selected as research objects.They were randomly divided into two groups.The comprehensive treatment was applied in both groups.In the observation group(n=52),de-escalation therapy was used,0.5mg/(kg·d)Prednisone for oral administration for 3 d,Salbutamol Sulfate solution for aerosol inhalation as required(2.5 mg each time),Ipratropium Bromide solution(125 μg each time for 7 d),and oral administration of 4 mg/d Montelukast for 14 d.In the control group (n=51),common treatments in clinic were used,like aerosol inhalation of Budesonide Suspension combined with or Inhalation of Salbutamol solution and Ipratropium Bromide solution as required to the stable period (2 weeks).The scores of symptoms and signs at different time points in the two groups were evaluated.The improvement of symptoms and signs 2 h,3 d,5 d,7 d after medication,disappearing time,and recurrent frequency of wheezing within one month follow up were observed.ResultsIn the observation group,the scores of improving wheezing,cough,and wheezing rale were higher than those in the control group (P<0.05).The disappearing time of these symptoms and signs was shorter compared with that in the control group(P<0.05).The recurrent frequency in the observation group within one month follow up was significantly lower than that in the control group,the difference was statistically significant(P<0.05).There was no drug adverse reaction in the two groups.ConclusionDrug combination de-escalation in the treatment of acute attack of wheezing in infants is remarkable on effect,safe and reliable.
2018 Vol. 25 (5): 65-67 [Abstract] ( 191 ) HTML (26 KB)  PDF  (0 KB)  ( 111 )
68 Effect analysis on the functional recovery of pelvic floor by postpartum pelvic floor muscle training
LAI Ting-ting ;LIANG Gui-ying; DU Ai-qi;LIU Meng-fei
ObjectiveTo explore the recovery effect of postpartum pelvic floor muscle training on pelvic floor function.MethodsFrom July 16,2015 to June 16,2017,400 puerperae with pelvic floor dysfunction in our hospital were evenly divided into two groups by drawing lots,200 cases in each group.The traditional training guidance was applied in control group,and comprehensive pelvic floor muscle training was applied in observation group.The functional recovery of pelvic floor and incidence of adverse events were compared between the two groups.ResultsIn the observation group,the fatigue degree of muscle fiber in grade Ⅱ in pelvic floor was(-0.01±0.01)%,and(-0.03±0.01)%in gradeⅠ muscle fiber of pelvic floor.The incidence of pelvic organ prolapse(2.00%)and urinary incontinence(2.50%)in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).The muscle voltage of gradeⅠandⅡ muscle fiber of pelvic floor were(8.45±1.35)μV and(8.63±1.24)μV.The rates of muscle strength in levels 4 and 5 by hand checking were 78.00%and 16.00%.The treatment compliance rate was reached 99.00%in the observation group.All these indexes mentioned above were higher than those in the control group,the difference was statistically significant(P<0.05).ConclusionFor puerpera suffering from postpartum pelvic floor dysfunction,implementation of comprehensive pelvic floor muscle training can decrease the incidence of urinary incontinence and pelvic organ prolapse,and improve muscle fiber fatigue.
2018 Vol. 25 (5): 68-70 [Abstract] ( 193 ) HTML (26 KB)  PDF  (0 KB)  ( 60 )
71 Clinical observation on the effect of multi-stapling technique on postoperative intestinal function and safety of patients with ultra-low rectal cancer
HUANG Zhong-gen ;DUAN Yong-hui;OUYANG Zhao-han
ObjectiveTo study the clinical efficacy of multi-stapling technique in the operation of ultra-low rectal cancer and its effect on the safety of postoperative intestinal function.MethodsFrom June 2010 to June 2015,32 patients with ultra-low rectal cancer were selected and randomly divided into control group and study group,16 cases in each group.In the study group,11 patients were treated by two anastomosis and 5 patients by three anastomosis.The control group was treated with conventional miles operation(i.e,transabdominal and perineal resection of rectal cancer).ResultsThe recovery time and operation time of gastrointestinal function in the study group were longer than those in the control group(P<0.05).There was no significant difference between the two groups(P>0.05)in the number of daily defecation after 3 d,1 month and 3 months.The survival time was(10.0±3.2)months of the study group and(11.0±2.9)months in the control group,there was no significant difference the two groups(P>0.05).ConclusionIn the course of operation for patients with ultra-low rectal cancer,application of multi-anastomat as an assistance during the operation can completely removemesorectum in a great clinical effect by fully ensuing the success rate and safety of anal preservation.Inaddition,itreduces the positive phenomenon of incisal edge in these postoperative patients,and better guarantees the quality of life in these patients after surgery compared with the traditional operation method.
2018 Vol. 25 (5): 71-73 [Abstract] ( 236 ) HTML (27 KB)  PDF  (0 KB)  ( 79 )
74 Effect of thymopentin combined with chemotherapy on T lymphocyte subsets in peripheral blood of patients with multiple myeloma
HU Ting; PENG Li-ping ;ZHANG Chen-xiao
ObjectiveTo investigate the effect of thymopentin combined with chemotherapy on T lymphocyte subsets in peripheral blood of patients with multiple myeloma.Methods24 patients with multiple myeloma diagnosed in our hospital from July 2016 to July 2017 were selected and randomly divided into chemotherapy group chemotherapy+thymopentin group,12 cases in each group.In the chemotherapy group,tad (thalidomide+epirubicin+dexamethasone)was used as the main chemotherapy regimen for 4 consecutive courses.In the chemotherapy plus thymopentin group,TAD was the main chemotherapy regimen and thymopentin was added for 4 consecutive courses.Total T cells(CD3+),helper/inducible t cells(CD4+),inhibition/cytotoxic T cells(CD8+)ratio and CD4+/CD8+ratio in peripheral blood lymphocytes were measured by flow cytometry before and after treatment.ResultsThere was no significant difference in cellular immune function between the two groups before chemotherapy(P>0.05).CD3+,CD4+positive percentage and CD4+/CD8+ratio of chemotherapy+thymopentin group were higher than those before chemotherapy and chemotherapy alone (P<0.05).The total effective rate of chemotherapy+thymopentin group was higher than that of chemotherapy group (P<0.05).Conclusions Thymopentin combined with chemotherapy can improve the immune function of patients with multiple myeloma,improve the effective rate,reduce the infection rate.
2018 Vol. 25 (5): 74-76 [Abstract] ( 178 ) HTML (28 KB)  PDF  (0 KB)  ( 103 )
77 Clinical effect of radiotherapy on radiation pneumonitis caused by lung cancer
CHEN Hai-wen; ZHANG Kun-qiang;YANG Chang-fu ;LU Yao-yong;WEI Hua-jun
ObjectiveTo investigate the clinical effect of radiation pneumonitis induced by lung cancer radiotherapy.Methods74 lung cancer patients with radiation pneumonitis caused by radiotherapy in our hospital from January 2013 to December 2016 were selected and divided into control group and observation group according to different treatment schemes,with 37 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with integrated traditional Chinese and Western medicine.The clinical efficacy,symptom improvement,inflammatory factor level,KPS score and adverse reactions were compared between the two groups.ResultsThe total effective rate of the observation group was significantly higher than that of the control group (P<0.05).After treatment,the symptom score of the observation group was significantly lower than that of the control group(P<0.05).After treatment,the white blood cell count and hs-CRP in the observation group were significantly lower than those in the control group (P<0.05).KPS score of observation group was significantly higher than that of control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was significantly lower than that in the control group(P<0.05).ConclusionRadiation pneumonitis caused by lung cancer radiotherapy has good effect,can effectively relieve symptoms,promote the regression of inflammation,improve the quality of life of patients,has a positive clinical significance.
2018 Vol. 25 (5): 77-79 [Abstract] ( 190 ) HTML (28 KB)  PDF  (0 KB)  ( 100 )
80 Influence of drug intervention on the quality of life in patients with advanced tumor and depression
GAO Jin-suo; WANG Jian-bing ;LIU Wei-wei;YANG Jin-zhu
ObjectiveTo investigate the effect of drug intervention on quality of life in patients with advanced tumor and depression.MethodsFrom April 2012 to April 2016,214 patients with advanced tumor complicated with standard depression were selected and randomly divided into experimental group(112 cases),control group(102 cases)and control group(102cases).The patients in the experimental group were treated with conventional anti-tumor therapy.on the basis of the treatment of the control group,the patients in the experimental group were treated with one tablet of Flupentixol Melitracen every morning and one tablet of Flupentixol Melitracen every day after lunch,and the patients>60 years old were treated with 1 tablet of Flupentixol Melitracen every day after breakfast.After 1,2,3 and 4 weeks,QOL scale was used to score again.ResultsThe QOL score of the experimental group at week 1-4 was significantly higher than that before treatment(P<0.05).The QOL score of the experimental group was higher than that of the control group(P<0.05),and the side effect of the experimental group was higher than that of the control group(P<0.05).ConclusionDrug intervention of Flupentixol Melitracen can improve QOL of patients with advanced tumor combined with depression,and without obvious adverse reactions,is worthy of clinical application.
2018 Vol. 25 (5): 80-82 [Abstract] ( 188 ) HTML (26 KB)  PDF  (0 KB)  ( 66 )
83 Clinical effect of Megestrol Acetate in the treatment of endometrial carcinoma
WANG Jing

ObjectiveTo investigate the clinical effect of Megestrol Acetate in the treatment of endometrial carcinoma.MethodsFrom July 2016 to July 2017,80 patients with endometrial cancer in our hospital were treated.According to their personal will,they were grouped.Among them,39 patients were treated with routine therapy,and the rest 41 patients with endometrial carcinoma treated with Megestrol Acetate on the basis of the control group for intensification.Patients treated by routine therapy was classified into control group,and by intensified treatment was categorized into observation group.The therapeutic effect and improvement of quality of life between the two groups were compared.ResultsAfter treatment,patients with endometrial cancer in the two groups occurred with gastrointestinal reactions to some extent.The incidence of gastrointestinal reaction in the observation group was 9.76%,significantly lower than that in the control group accounting for 35.90%with a statistical difference(P<0.05).The recurrence rate was 7.32%in the observation group and 30.77%in the control group,which was displayed statistical significance after comparison (P<0.05).The scores of quality of life in the observation group were all higher than those in the control group (P<0.05).ConclusionApplication of Megestrol Acetatein the treatment of endometrial cancer obtains a definite clinical value.It not only reduces the patient′s gastrointestinal reaction and recurrence rate,but also markedly improve the quality of life in endometrial cancer patients,which plays a vital role in clinical practice and is worthy of further study and exploration.
2018 Vol. 25 (5): 83-85 [Abstract] ( 180 ) HTML (23 KB)  PDF  (0 KB)  ( 96 )
86 CIK cells in the treatment of digestive system tumors
SUN Jie;WANG Xing;WANG Cui-fang;ZHANG Chun-yang
ObjectiveTo investigate the therapeutic effect of cik cells on digestive system tumors.MethodsFrom January 1,2012 to February 25,2014,100 cases of digestive system tumor patients in our hospital were selected as the research objects,according to the differences in treatment measures of digestive system tumor patients were divided into control group,experimental group,50 cases in each group.The control group was treated with palliative treatment,while the experimental group was treated with CIK cells.The difference of treatment results between the two groups were compared.ResultsThe levels of CD3+and CD3+CD8+in the experimental group were significantly higher than those in the control group (P<0.05).There was no significant difference between the two groups in OS and PFS (P>0.05).The quality of life of the experimental group was significantly better than that of the control group(P<0.05).The tumor markers(CA 724,CA199)in the experimental group were significantly lower than those in the control group (P<0.05).There was no significant difference in the level of peritoneal effusion between the two groups (P>0.05).ConclusionPatients with digestive system tumors receiving CIK cell therapy can improve their immunity,living standards and tumor markers,but there is no significant improvement in survival time,peritoneal effusion and other aspects.
2018 Vol. 25 (5): 86-88 [Abstract] ( 178 ) HTML (26 KB)  PDF  (0 KB)  ( 71 )
89 Clinical effect of transurethral resection of bladder tumor combined with epirubicin in the treatment of non muscle invasive bladder cancer
HUANG Zhi-cheng;PENG Dong;CHEN Zhi-lin; WAN Pei;ZHU Yu-guang;CHEN Nan-hui
ObjectiveTo explore the clinical effect of transurethral bladder tumor vaporizing electrotomy combined with epi in the treatment of non-muscular infiltrating bladder cancer.Methods40 patients of non-muscle invasive bladder cancer treated in our hospital from March 2014 to March 2016 were divided into observation group (n=20)and control group (n=20).Two groups were given transurethral electrovaporization of bladder tumor treatment,the control group with hydroxycamptothecin or mitoxantrone for bladder perfusion,observation group with epirubicin for bladder perfusion.The catheter indwelling time,operation time,adverse reactions and recurrence were compared between the two groups.ResultsThere was no significant difference in indwelling time and operation time between the two groups(P>0.05).There was no significant difference in the incidence of adverse reactions between the two groups(χ2=0.28,P=0.60).There was no significant difference in recurrence rate between the two groups (χ2=0.20,P=0.66).ConclusionTransurethral electrovaporization resection of bladder tumor combined with epirubicin in the treatment of non-muscle invasive bladder cancer is effective,the recurrence rate is low,worthy of promotion.
2018 Vol. 25 (5): 89-91 [Abstract] ( 134 ) HTML (26 KB)  PDF  (0 KB)  ( 65 )
92 Clinical application of Waveone system combined with one-off method in the periapical periodontitis of the anterior deciduous teeth
LIN Yan
ObjectiveTo analyze the application effect of waveone system combined with one-off root canal therapy in chronic periapical periodontitis of the anterior deciduous teeth.MethodsFrom September 2016 to August 2017,50 patients with chronic periapical periodontitis of the anterior deciduous teeth treated in our outpatient clinic were selected as research objects.They were divided into the observation group(n=50)and control group(n=50)by computer random sampling method.In the observation group,Waveone system was used.In the control group,traditional stainless steel k file was used for root canal preparation.The two groups were both treated with one-off root canal therapy and filling.The time of root canal preparation and postoperative effect between the two groups were compared.ResultsThe preparation time in the observation group and control group was(5.13±0.15)s and(7.26±0.19)s respectively with a statistical difference (P＜0.05).In the observation group,the total postoperative effectiveness rate was 96%,and 72%in the control group,which was displayed a statistical difference (P<0.05).ConclusionFor the treatment of chronic periapical periodontitis of anterior deciduous teeth,application of Waveone combined with one-off root canal therapy can obtain a remarkable effect,and effectively shorten the operation time,which is worthy of clinical promotion.
2018 Vol. 25 (5): 92-94 [Abstract] ( 174 ) HTML (26 KB)  PDF  (0 KB)  ( 73 )
95 Clinical effect of orthodontics combined implantation in the treatment of congenital missing teeth
GAO Yang;LI Hui-shan;LI Xiao-ming;WANG Ruo-li;WU Da-lei
ObjectiveTo investigate the clinical effect of orthodontics combined with implantation in the treatment of congenital missing teeth.MethodsA total of 100 patients with congenital missing teeth who were admitted into the Department of Stomatology in Dalian Friendship Hospital and the Second Hospital Affiliated to Dalian Medical University from February 20,2015 to July 30,2016 were selected as the research subjects.According to the differences of treatment measures,the patients were divided into the control group(n=50)and experimental group(n=50).The control group was given dental implantation treatment,and the experimental group was given orthodontic treatment and implantation treatment at the same time.The therapeutic effect of the two groups was compared.ResultsThe total effective rate was 96.00%in the experimental group,which was significantly higher than that of 76.00%in the control group(P<0.05).The chewing function and language function of the two groups after treatment were better than those before treatment.The improvement degree of chewing function and language function in the experimental group was better than that in the control group (P<0.05).The incidence of adverse reaction in the experimental group was significantly lower than that in the control group(P<0.05).ConclusionPatients with congenital missing teeth receiving orthodontics combined with implantation can achieve better results,which is able to promote the recovery of relevant function of missing teeth,and has a higher safety and great significance.
2018 Vol. 25 (5): 95-97 [Abstract] ( 173 ) HTML (26 KB)  PDF  (0 KB)  ( 64 )
98 Clinical effect analysis of orthodontic treating anterior teeth displacement caused by periodontal disease
ZHAO Yang
ObjectiveTo study the clinical effect of orthodontic treatment treating anterior teeth displacement caused by periodontal disease.MethodsFifty patients with anterior teeth displacement caused by periodontal diseases from March 2013 to May 2015 treated in our hospital were selected as research objects.On the basis of the basic treatment of periodontal disease,theorthodontic treatment was provided.The depth of periodontal pocket,tooth bleeding,anterior alveolar height,overlying and covering index of anterior teeth indexes were compared before treatment,end of treatment and after 1 year treatment.ResultsAfter treatment,at the end of treatment,the depth of periodontal pocket,tooth bleeding,anterior alveolar height,overlying and covering index of anterior teeth indexes were significantly improved compared with before treatment(P<0.05).After 1 year treatment,the above indexes were all good.All 50 patients were successfully completed the treatment.All patients had normal periodontal ligament clearance.The anastomosis degree of tooth occlusion was higher,and the loosening of teeth was improved,which accords with the aesthetic requirements of patients.ConclusionOrthodontic treatment for anterior teeth displacement caused by periodontal disease has a good effect on periodontal control.It improves the masticatory function of patients,maintains the beautiful periodontal appearance in a remarkable effect,and it is worthy of clinical application and promotion.
2018 Vol. 25 (5): 98-100 [Abstract] ( 151 ) HTML (25 KB)  PDF  (0 KB)  ( 80 )
101 Effect analysis of the eustachian tube balloon dilation treating chronic secretory otitis media
LIN Si-ping;ZHANG Zhi-gang
ObjectiveTo discuss the clinical effect of the eustachian tube balloon dilation (ETBD)treating chronic secretory otitis media.Methods57 patients (61 ears)with chronic secretory otitis media treated in People′s Hospital of Puning City from January 2015 to February 2016 were selected and they were randomly divided into the observation group(29 patients,31 ears)and control group(28 patients,30 ears)according to hospital sequence.Patients in the observation group were treated with ETBD,while patients in the control group were treated with grommet insertion.Eustachian tube dysfunction(ETD),pure toneaudiometry(PTA)and treatment effect were compared between the two groups.ResultsETDQ-7 score in patients of the observation group was significantly lower than those of the control group after 6,12 and 18 months operation(P<0.05).PTA in patients of the observation group was significantly lower than that of the control group after 12 months operation (P<0.05).The effective rate of the observation group (83.9%,93.5%)was significantly higher than that of the control group(56.7%,43.3%)at after 12,18 months operation(P<0.05).ConclusionETBD treating chronic secretory otitis media can significantly relieve the clinical symptoms of the patients and improve the clinical effect.
2018 Vol. 25 (5): 101-103 [Abstract] ( 145 ) HTML (26 KB)  PDF  (0 KB)  ( 64 )
104 Clinical effect of non-traumatic repair technology treating elderly dental caries
WU Li-jun
ObjectiveTo investigate the clinical effect of non-traumatic repair technology treating elderly dental caries.MethodsFrom November 27,2015 to March 22,2017,66 elderly patients with dental caries treated in our hospital were selected to study,and they were divided into the control group(n=33)and observation group(n=33)according to different treatment methods.The control group was given conventional treatment,while the observation group was given nontraumatic repair technology.he clinical effects,quality of life and the satisfaction degree of patients were observed in the two groups.ResultsThe success rate in the observation group for 3 and 6 months treatment was 100.00%and 96.97%respectively,which were higher than those in the control group (P<0.05).After treatment,the score of social relation,material life,physiological function and mental status in the observation group was(84.11±3.09),(86.05±2.97),(85.09±3.11)points,and(80.69±2.77)points respectively,which were all higher than those in the control group(P<0.05).The total satisfaction rate of the observation group(96.97%)was higher than that of the control group(P<0.05).ConclusionThe effect of nontraumatic repair technology treating elderly dental caries is better.
2018 Vol. 25 (5): 104-106 [Abstract] ( 164 ) HTML (24 KB)  PDF  (0 KB)  ( 111 )
107 Study of SIMV mode in general anesthesia assisted by laryngeal mask in the subtotal thyroidectomy for the elderly
YAN Kai-shu; LIAO Xi-qiang; ZHAO Chong-han; CHEN Zhen-ai
ObjectiveTo explore the efficacy and safety of laryngeal mask assisted synchronous intermittent mandatory ventilation (SIMV)mode in general anesthesia for elderly patients undergoing subtotal thyroidectomy.MethodsA total of 60 patients who were no less than 65 years old in ASAⅠ-Ⅲ grade with subtotal resection from April 2015 to April 2016 were selected as research objects.They were evenly divided into the experimental group and the control group by a random and double blind method.In the experimental group,laryngeal mask assisted SIMV mode in general anesthesia was implemented,while in the control group,conventional tracheal intubation anesthesia was adopted.The hemodynamics before and after anesthesia,respiratory function recovery,and anesthesia related complications were observed between the two groups.ResultsCompared the level of systolic blood pressure (SBP),diastolic blood pressure (DBP),and heart rate(HR)at T0in the two groups,there was significant difference in the two groups from T1to T3(P＜0.05).In the experimental group,the level of SBP,DBP,and HR from T1to T2were higher compared with those in the control group,with statistical differences(P＜0.05).The dose of anesthesia in the experimental group was lower than those in the control group,the first extubation time,and time to leave operation room in the experimental group was shorter than those in the control group,which were displayed statistical differences(P＜0.05).The incidence of anesthesia-related complications in the experimental group was 6.67%,which was lower than that in the control group accounting for 26.67%,with a statistical difference(P＜0.05).ConclusionLaryngeal mask assisted SIMV mode in general anesthesia is beneficial to maintain the hemodynamic stabilityin elderly patients undergoing subtotal thyroidectomy,and shorten awakening time with few complications,which has a better application value.
2018 Vol. 25 (5): 107-109 [Abstract] ( 179 ) HTML (28 KB)  PDF  (0 KB)  ( 95 )
110 Effect of Flurbiprofen Axetil combined with Sufentanil on postoperative analgesia in laparoscopic total hysterectomy
YE San-chun
ObjectiveTo investigate the effect of Flurbiprofen Axetil combined with Sufentanil on postoperative analgesia in laparoscopic total hysterectomy.MethodsA total of 200 patients with laparoscopic total hysterectomy in our hospital from May 2015 to July 2016 were selected as research objects.All of the patients were randomly divided into the study group and the control group,with 100 cases in each group.Patients in the control group were given Sufentanil and Droperidol analgesia,and the patients in the study group were treated with Flurbiprofen Axetil on the basis of the control group.The visual analogue scale (VAS)of the two groups were evaluated at 1,4,8,16,24,48 h,and the adverse reactions were observed.ResultsThe VAS scores of the study group at 1,4,8,16,24,48 h were significantly lower than those in the control group,with significant difference (P＜0.05).The incidence of adverse reactions such as dizziness,pruritus,respiratory depression,nausea,vomiting and gastrointestinal ulcer in the study group were significantly lower than those in the control group,the difference was statistically significant(P＜0.05).ConclusionFlurbiprofen Axetil combined with Sufentanil for postoperative analgesia in laparoscopic total hysterectomy is effective and less adverse reactions,so it is worthy of clinical promotion and application.
2018 Vol. 25 (5): 110-112 [Abstract] ( 149 ) HTML (24 KB)  PDF  (0 KB)  ( 60 )
113 Application of epidural use of compound solution of Dexmedetomidine and Ropivacaine on patients undergoing repeated cesarean section
WU Xia;YU Li;JIANG Xiu-hong;HE Ming-feng
ObjectiveTo observe the effect of epidural use of Dexmedetomidine and Ropivacaine on patients undergoing repeated cesarean section.MethodsA total of 40 parturient,treated in Jiangsu Women and Children Health Care Hospital from December 2015 to December 2016,scheduled for repeated cesarean section under epidural anesthesia were selected randomly.According to the random number table method,the patients were divided into group D and group R,with 20 patients in each group.0.75%Ropivacaine 15 ml was administered epidurally,with addition of 0.5 μg/kg of Dexmedetomidine in group D,and 2 ml of normal saline in group R.Mean arterial pressure(MAP),heart rate(HR)before anesthesia (T0),at 10 min after administration of the specific drugs (T1),at 30 min after administration of the specific drugs(T2),and end of surgery (T3)were recorded.The onset time of epidural sensory block,maximum sensory analgesic level,the time to maximum sensory analgesic level,the time of sensory block were collected.The modified Bromage scale,Ramsay grade and grade of traction reaction at T2,cases who used remifentanil,incidence of respiration inhibition and shiver were also assessed.Blood from umbilical veins was collected for blood gas analysis.The Apgar scores were evaluated at 1 and 5 min.ResultsThere was no significant difference in the MAP and HR at T0,T1,T2and T3between the two groups(P＞0.05).The onset time of epidural sensory block and the time to maximum sensory analgesic level in group D was shorter than that in group R,and the time of sensory block in group D was longer than that of group R,with significant difference (P＜0.05).The degree of sedative satisfaction in group D was higher than that in group R,the effect of traction reaction in the operation in group D was less than that of group R,and the proportion of the use of Remifentanil in group D was lower than that of group R,and the incidence of respiratory inhibition in group D was lower than that in group R,with significant difference (P＜0.05).The score of Apgar at 1 min after birth in group D was higher than that in group R,with significant difference(P＜0.05).ConclusionFor patients undergoing repeated cesarean section,epidural use of Dexmedetomidine combined with Ropivacaine can enhance the anesthetic effect,without obvious adverse maternal or neonatal effects.
2018 Vol. 25 (5): 113-116 [Abstract] ( 182 ) HTML (37 KB)  PDF  (0 KB)  ( 72 )
117 Clinical analysis of Dexmedetomidine combined with small dose Propofol in painless fiberoptic bronchoscopy
ZHANG Xin
ObjectiveTo explore the clinical effect of Dexmedetomidine combined with small dose of Propofol in painless fiberoptic bronchoscopy.Methods80 patients with painless fiberoptic bronchoscopy from July 2016 to July 2017 were selected as the research subjects.They were divided into the study group and the control group according to the form of the single and double number of the inpatient number,40 cases in each group.The study group was treated with Dexmedetomidine and low dose of Propofol,and the control group was given 2.5 mg/kg Propofol injection.The time of anesthesia recovery,the time of anesthesia induction,the recovery time of directional force and the incidence of adverse reactions were compared between the two groups.ResultsThe time of anesthesia recovery,the time of anesthesia induction and the recovery time of the directional force in the study group were shorter than those in the control group,with significant difference (P＜0.05).The incidence of adverse reactions in the study group was lower than that of the control group,with significant difference(P＜0.05).ConclusionThe effect of Dexmedetomidine combined with low dose of Propofol is significant in the treatment of painless bronchoscopy,which can effectively shorten the time of anesthesia induction and the time of anesthesia awakening.At the same time,the adverse reaction is less and the anesthesia is safe and worthy of clinical promotion.
2018 Vol. 25 (5): 117-119 [Abstract] ( 190 ) HTML (26 KB)  PDF  (0 KB)  ( 108 )
120 Study on the effect of Estradiol and Drospirenone Tablets combined with Kuntai Capsules in the treatment of menopausal syndrome
XU Xiao-xiu
ObjectiveTo investigate the effect of Estradiol and Drospirenone Tablets combined with Kuntai Capsules in the treatment of menopausal syndrome.MethodsA total of 124 patients with menopausal syndrome treated in our hospital from January 2016 to January 2017 were selected as subjects and they were divided into two groups according to the random principle,each with 62 cases.The patients in the control group were treated with Estradiol and Drospirenone Tablets,and the patients in the study group were treated with Estradiol and Drospirenone Tablets combined with Kuntai Capsules.The changes of total cholesterol(TC),triglyceride(TG),high-density lipoprotein(HDL-C),bone density,endometrial thickness and modified Kupperman score were compared between the two groups before and after treatment.ResultsAt the time of diagnosis,the improved Kupperman score and the thickness of endometrium were not statistically significant in both groups(P>0.05).3 months after treatment,the improved Kupperman score in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05),while there was no significant difference in endometrial thickness between the two groups(P>0.05).The density of spine,femoral bone and cervical bone in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The TG and HDL-C in the study group were higher than that in the control group,and TC was lower than the control group,and the difference was statistically significant(P<0.05).ConclusionThe effect Estradiol and Drospirenone tablets combined with Kuntai Capsules in the treatment of menopausal syndrome is more favorable,which is worthy of promotion and application.
2018 Vol. 25 (5): 120-122转125 [Abstract] ( 198 ) HTML (28 KB)  PDF  (0 KB)  ( 96 )
123 Effect of Omeprazole on uric acid in patients with upper gastrointestinal bleeding
Liu Shi-jie ；Zhu Sheng-huang； Xiao Feng-lian ；Liu Chun-mei；Xia Jun-chao
ObjectiveTo analyze the effect of Omeprazole on uric acid in patients with upper gastrointestinal bleeding.Methods50 patients with upper gastrointestinal hemorrhage admitted in our hospital from October 2015 to March 2017 were selected as subjects and divided into control group and observation group by voluntary way,with 25 cases in each group.Patients in the control group were treated with Cimetidine and patients in the observation group were treated with Omeprazole.The serum uric acid (SUA)values and serum urea nitrogen values of the two groups of patients were observed and recorded,and SUA values of different blood loss and symptoms were compared between the two groups.ResultsThere was no statistically significant difference in SUA values at admission and serum urea nitrogen when bleeding between the two groups(P>0.05).The SUA in the observation group was significantly higher than that in the control group after 2 weeks of bleeding,and the serum urea nitrogen after the cessation of bleedingas significantly lower than that in the control group,and the differences were statistically significant(P<0.05).The SUA of patients with the bleeding>1000 ml,the bleeding 500-1000 ml were compared between the two groups,and the differences were not statistically significant(P>0.05).The SUA of patients with the bleeding<500 ml,had shock symptoms and not shock in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).ConclusionOmeprazole can affect uric acid to some extent,and promote uric acid to be normal.
2018 Vol. 25 (5): 123-125 [Abstract] ( 227 ) HTML (23 KB)  PDF  (0 KB)  ( 57 )
126 Clinical observation of Telmisartan combined with Sulodexide for diabetic kidney disease at stageⅢ
FANG Hai-ming
ObjectiveTo investigate the clinical efficacy of Telmisartan combined with Sulodexide in the treatment of diabetic nephropathy.Methods64 patients with diabetic kidney disease at stageⅢtreated in our hospital from March 2015 to March 2017 were selected as subjects of this study.They were divided into control group and study group with random number table method,32 cases in each group.Two groups of patients were treated with conventional therapy,the patients of control group were given Telmisartan on the addition of conventional treatment,the patients of study group were given Telmisartan and Sulodexide on the basis of conventional treatment,all patients were treated for 8 weeks.The total effective rate of treatment,the serum creatinine(Scr),urea nitrogen(BUN),microprojection rate(UAER),high sensitivity C-reactive protein(hs-CRP)and tumor necrosis factor-α (TNF-α)before and after 8 weeks of treatmen were comapred between two groups.ResultsThe total effective rate in the study group(93.75%)was higher than that in the control group(68.75%),and the difference was statistically significant(P<0.05).There was no significant difference in the Scr,BUN and UAER between the two groups before treatment(P>0.05).After treatment,the UAER in both groups were lower than before treament,the UAER in the study group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in hs-CRP and TNF-α in the two groups(P>0.05).After treatment,the levels of hs-CRP and TNF-α in both groups were significantly lower than before treatment,and the levels of hs-CRP and TNF-α in the study group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).ConclusionThe efficacy of Telmisartan combined with Sulodexide in the treatment of diabetic kidney disease is significantly better than that of telmisartan alone,and it is recommended to be widely used clinically.
2018 Vol. 25 (5): 126-128 [Abstract] ( 156 ) HTML (26 KB)  PDF  (0 KB)  ( 79 )
129 Comparison of clinical effect of preauricular and postauricular injection of Dexamethasone and Gentamicin in the treatment of Meniere's disease
LING Yong-wei
ObjectiveTo investigate the clinical effect of preauricular and postauricular injection of Dexamethasone and Gentamicin in the treatment of Meniere′s disease.MethodsAltogether 90 patients with Meniere′s disease who were treated in our hospital from January 2015 to January 2017 were selected as subjects and divided into research group and control group according to the random number table method.Patients in both groups were treated with Dexamethasone and Gentamicin,and the control group was treated with preauricular injection,and the group was treated with postauricular injection.The improvement effects in auditory function,vestibular function and movement ability were compared between two groups of patients.ResultsThe hearing function improvement rate (33.33%),the vertigo control rate(77.78%)and the activity ability improvement rate(80.00%)in patients of research group were significantly higher than those of the control group(13.33%,57.78%,13.33%),the differences were statistical significance(P<0.05).ConclusionCompared with preauricular injection of Dexamethasone and Gentamicin in the treatment of Meniere′s disease,postauricular medication achieves more obvious effects in improving patients′auditory function,vestibular function and movement ability.
2018 Vol. 25 (5): 129-131 [Abstract] ( 164 ) HTML (28 KB)  PDF  (0 KB)  ( 106 )
132 Evaluation of clinical effect and therapeuticsafety of Relinqing combined with Levofloxacin in the treatment of chronic bacterial prostatitis
CHEN Yi-de；ZHANG Yong-ke；LONG Qi；SONG Shao-kang
ObjectiveTo explore the clinical effect of Relinqing combined with Levofloxacin in thetreatment of chronic bacterial prostatitis and evaluate its therapeutic safety.MethodsFrom May 2015 to May 2017,100 patients diagnosed as chronic bacterial prostatitis treated in our hospital were selected as subjects.By a random number table mathod,they were evenly divided into research group and control group,50 cases in each group.The patients in the control group was treated with Levofloxacin,while the research group was treated wuth Relinqing combined with Levofloxacin.The treatment effect,the white blood cell index of the prostatic fluid(EPS-WBC),the prostate inflammation index(CPSI)and the incidence of adverse reactions of the two groups were compared.ResultsThe total effective rate of the patients in the study group(98.00%)was higher than that in the control group(78.00%),and the difference was statistically significant(P<0.05).After treatment,the EPS-WBS and CPSI of the study group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).ConclusionCombination of Relinqing and Levofloxacin obtains a remarkable effect on treating chronic bacterial prostatitis by improving patients′clinical symptoms in few adverse reactions,which is worthy of clinical promotion.
2018 Vol. 25 (5): 132-134 [Abstract] ( 176 ) HTML (26 KB)  PDF  (0 KB)  ( 48 )
135 Effect of Dopamine combined with Dobutamine on chronic heart failure with renal insufficiency
ZHANG Qing
ObjectiveTo investigate the effect of Dopamine combined with Dobutamine in the treatment of chronic heart failure complicated with renal insufficiency.MethodsA total of 60 patients with chronic heart failure complicated with renal insufficiency admitted in our hospital from February 2014 to September 2016 were selected as subjects,and they were divided into observation group and control group by random distribution,30 cases in each group.The control group was treated with conventional drugs.The observation group was treated with Dopamine and Dobutamine.The effects of treatment,adverse reactions and the left ventricular diastolic(LVEDD),left ventricular ejection fraction(LVEF)and blood urea nitrogen(BUN)of the two groups were compared.ResultsThe total effective rate in the observation group(93.33%)was higher than that in the control group(73.33%),and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference between the two groups of patients with heart and kidney function(P>0.05).After treatment,the LVEDD and BUN were lower than before treatment in both groups,the LVEF was higher than before the treatment,and the differences were statistically significant(P<0.05).The LVEDD and BUN of patients in the observation group were significantly lower than those in the control group,while the LVEF was significantly higher than that in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group(6.67%)was lower than that in the control group(26.67%),and the difference was statistically significant(P<0.05).ConclusionThe clinical effect of Dopamine combined with Dobutamine in the treatment of chronic heart failure complicated with renal insufficiency is significant,which can reduce the incidence of adverse reactions and effectively improve the clinical symptoms of patients,it is worthy of clinical promotion.
2018 Vol. 25 (5): 135-137 [Abstract] ( 196 ) HTML (25 KB)  PDF  (0 KB)  ( 75 )
138 The clinical effect of Gemcitabine combined with Dolitaxel in treatment of advanced lung adenoid squamous carcinoma
AN Shi-xing
ObjectiveTo explore the clinical effect of Gemcitabine combined with Dolitaxel in the treatment of advanced lung adenoid squamous carcinoma.Methods92 patients with advanced lung adenocarcinoma treated in our hospital from October 2013 to January 2017 were selected as the study subjects,and were randomly divided into observation group and control group according to the random number table method,46 cases in each group.The patients in the control group were treated with Docetaxel,and the patients in the observation group were given Gemcitabine for combined treatment on this basis.The treatment effect,average survival time (OS)and adverse reactions were compared between the two groups.ResultsThe treatment of total effective rate of patients in the observation group (91.30%)was lower than that in the control group (78.26%),and the difference was statistically significant(P<0.05).In observation group,the average OS was(25.59±4.59)months,while the average OS in the control group was(13.49±2.91)months,the average OS in the observation was longer than that in the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in adverse reactions between the two groups(P>0.05).ConclusionThe clinical effect of Gemcitabine combined with Dolitaxel in the treatment of advanced lung adenoid squamous cell carcinoma is significant,which can obviously improve the survival time of patients and has high clinical application value and is worth promoting.
2018 Vol. 25 (5): 138-140 [Abstract] ( 198 ) HTML (25 KB)  PDF  (0 KB)  ( 63 )
141 Effect of Qianlieqing Decoction combined with western medicine in the treatment of chronic bacterial prostatitis with the type of downward flow of damp-heat
HUANG Xiao-qing ;SU Jin-song ;WU Jiang-ping;XU Yun-sen ;GUO Yu-ming ;YAN Wen-bing ;ZHAO Huo ;LONG Yun ;TIAN Li-xin
ObjectiveTo observe the effect of Qianlieqing Decoction combined with antibiotics and tamsulosin in the treatment of chronic bacterial prostatitis with the type of downward flow of damp-heat.MethodsFrom May 2012 to June 2016,80 patients with chronic bacterial prostatitis with the type of downward flow of damp-heat admitted into the department of andrology in our hospital were selected and they were randomly divided into the treatment group and the control group,with 40 cases in each group.Both groups were given orally antibiotics and Tamsulosin.The treatment group was further given Qianlieqing Decoction.The course of treatment was 4 weeks.ResultsThere was a significant difference in TCM symptom score in the two groups after treatment compared with those before the treatment(P<0.05).The score of TCM symptom in the treatment group was significantly lower than that in the control group (P<0.05).The total effective rate in the treatment group was 95%,and the control group was 67.5%,and the difference between the two groups was statistically significant(P<0.05).ConclusionQianlieqing Decoction combined with antibiotics and Tamsulosin in the treatment of chronic bacterial prostatitis with the type of downward flow of damp-heat can better reduce TCM symptom score,improve clinical symptom of patients and improve the curative effect,which is significantly superior to the simple western medicine treatment.
2018 Vol. 25 (5): 141-144 [Abstract] ( 164 ) HTML (33 KB)  PDF  (0 KB)  ( 106 )
145 Clinical effect analysis of Chinese medicine directional drug penetration therapy combined with Budesonide atomization treating auxiliarily bronchopneumonia
HUANG Xue-wei
ObjectiveTo investigate clinical effect of Chinese medicine directional drug penetration therapy combined with Budesonide atomization treating auxiliarily bronchopneumonia.Methods196 patients with bronchopneumonia treated in our hospital from October 2013 to October 2016 were selected and they were randomly divided into the two groups.98 patients treated Budesonide atomization were selected as the control group while 98 patients treated chinese medicine directional drug penetration therapy combined with Budesonide atomization were selected as the observation group.ResultsAfter treatment,C reactive protein,white blood cell count,TCM symptoms and signs integral were decreased in the two groups and the above-mentioned indexes in the observation group were all lower than those in the control group(P<0.05).The total effective rate of the observation group was higher than that of the control group(P<0.05).The antipyretic time,cough disappeared time,wheezing disappearance time,pulmonary rales disappeared time,hospitalization time in the observation group were shorter than those of the control group(P<0.05).There was no significant difference in theincidenceofadversereactionsbetweenthetwogroups(P>0.05).ConclusionChinesemedicinedirectionaldrugpenetration therapy combined with Budesonide atomization have significant effect in treatment for bronchopneumonia and high safety.
2018 Vol. 25 (5): 145-147 [Abstract] ( 193 ) HTML (27 KB)  PDF  (0 KB)  ( 102 )
148 Clinical effect observation of modified Anshen Decoction in the treatment of insomnia of type liver depression and qi stagnation
LIN Du-feng
ObjectiveTo observe the clinical effect of modified Anshen Decoction in the treatment of insomnia of liver depression and qi stagnation type.MethodsFrom January 2015 to January 2017,97 insomnia patients with type liver depression and qi stagnation treated in our hospital were selected.They were divided into the two groups according to the random permutation table method.In the control group (n=48),Lorazepam Tablets was used,while in the observation group,Anshen Decoction was added.The sleeping quality before and after treatment was compared in order to evaluate the therapeutic effect.The quality of sleep and TCM syndrome score of the two groups were compared before and after treatment,and the therapeutic effect was evaluated.ResultsThe total effective rate of the observation group was 95.9%,which was higher than that of the control group(85.4%)(P<0.05).The various score of sleep quality of the patients in the observation group after treatment was significantly lower than that of the control group reapectively (P<0.05).The score of TCM syndrome in patients of the observation group after treatment was significantly lower than that of the control group (P<0.05).ConclusionThe clinical effect of modified Anshen Decoction in the treatment of insomnia of liver depression and qi stagnation type is better,and can obviously improve the quality of sleep for patients and can be promoted and applied in clinic.
2018 Vol. 25 (5): 148-150转153 [Abstract] ( 175 ) HTML (27 KB)  PDF  (0 KB)  ( 79 )
151 Effect evaluation of Yaobitong combined with Mecobalamin in the treatment of lumbar disc herniation
ZHANG Yong-jun；LIN fen-qiang；WEI Yu-guang
ObjectiveTo evaluate the effect of Yaobitong combined with Mecobalamin in the treatment of lumbar disc herniation.Methods94 patients with lumbar disc herniation treated in our hospital from January 2015 to December 2016 were selected as the object of this study.They were divided into the observation group (n=47)and control group(n=47)according to the random number method.The patients in the control group were treated with Mecobalamin.The patients in the observation group were treated with Yaobitong Capsules and Mecobalamin.The total effective rate,VAS score before and after treatment,serum MDA and SOD level before and after treatment were observed and recorded in the two groups.ResultsThe total effective rate of observation group after 4 weeks was higher than the control group,and the difference was statistically significant(P<0.05).After treatment,VAS score of the observation group was lower than the control group,and the difference was statistically significant(P<0.05).After treatment,serum MDA level in the observed group was lower than that of the control group,and serum SOD level was higher than that of the control group,and the difference was statistically significant(P<0.05).ConclusionThe effect of Yaobitong combined with Mecobalamin treating lumbar disc herniation is significant.It can effectively improve the total effective rate of treatment,in reducing the patients′pain,reducing serum MDA level and enhancing the serum SOD level shows a positive significance.It is worthy of clinical promotion and application.
2018 Vol. 25 (5): 151-153 [Abstract] ( 340 ) HTML (25 KB)  PDF  (0 KB)  ( 105 )
154 Clustering analysis on incidences of three common gynecological cancers of 31 provincial-level administrative regions of China
LIU Bing；LIU Guo-hua；XU Dong-yu
ObjectiveTo study the characteristics of distribution and regional differences of the incidences of three common gynecological cancers since 2015 so as to provide references for preventing these three gynecological cancers.MethodsThe report of incidences of breast cancer,cervical cancer and ovarian cancer were collected of 31 provinciallevel administrative regions of China since 2015,and then statistical description,correlation analysis and clustering analysis were made on the incidences.The method of cluster analysis adopted Ward method,and the distance between classes was square Euclidean method.ResultsThe Spearman correlation analysis reported incidences of breast cancer,cervical cancer and ovarian cancer had pairwise correlation (P<0.05).The result of clustering analysis hinted that provinces of Liaoning,Anhui,Henan,Sichuan,Chongqing,Gansu,Heilongjiang,Jiangxi,Yunnan,Xinjiang and Fujian,which were at the forefront of incidences of breast cancer,cervical cancer and ovarian cancer,were first clustered into one group.While Xinjiang and Fujian,which had high incidence of breast and cervical cancer,were easily divided into one category.ConclusionPrevention and treatment of these three common gynecological cancers is still severe,with obvious characteristics in high-prevalence area,so focus should be on strengthening the prevention and treatment work of these three cancers in such regions.Active treatment intervention was adopted for patients diagnosed with three kinds of cancer to improve the quality of life and improve their survival rate.
2018 Vol. 25 (5): 154-156 [Abstract] ( 177 ) HTML (26 KB)  PDF  (0 KB)  ( 53 )
157 Investigation on the awareness of the knowledge of syphilis prevention among residents in Humen town of Dongguan city
CHEN You-nian ；WU Shao-bin ；LI Guo-qiang
ObjectiveTo investigate the awareness of the knowledge of syphilis prevention among residents in Humen town of Dongguan city.MethodsMultistage cluster sampling method was adopted to investigate the urban residents(n=150)and migrant workers(n=150)from March to October 2017.The survey included the basic situation of residents and the awareness of the knowledge of syphilis prevention.ResultsThe accuracy of the questions in the questionnaire of 300 respondents was 35.3%-92.0%,the lowest accuracy item was “syphilis can increase the spread of HIV/AIDS”(35.3%),the highest accuracy item was “syphilis is a venereal disease” (92.0%).The awareness rate for syphilis prevention knowledge of urban residents was 58.00% (87/150),while the awareness rate for syphilis prevention knowledge of floating population was 49.33% (74/150).The awareness rate for syphilis prevention knowledge of urban residents was compared with the floating population,the difference was statistically significant(χ2=2.266,P=0.132).Residents syphilis prevention knowledge acquisition way to select the top three frequency source were respectively:network(23.6%),television (22.1%)and promotion (14.4%),these were the main source of residents to acquir the syphilis prevention knowledge,while the proportion of professional approaches such as doctor consultation(5.6%)and school lecture(2.2%)was low.ConclusionThe awareness rates of the knowledge of syphilis prevention are relatively low in urban residents and migrant workers in Humen town of Dongguan city.Publicity and intervention in various ways should be used to raise the population awareness rate of syphilis prevention knowledge.
2018 Vol. 25 (5): 157-159 [Abstract] ( 156 ) HTML (26 KB)  PDF  (0 KB)  ( 85 )
160 Analysis of the causes of death in patients with hypertension
XU Min-bo; LIN Kun
ObjectiveTo investigate the causes of death in hypertensive patients in hospital.Methods357 hypertensive patients in hospital who died in our hospital from January 2015 to September 2017 were selected as the subjects.The clinical data of the patients were analyzed to understand the age and gender distribution of the patients.At the same time,the classification of hypertension and the main causes of death were summarized.ResultsThe mortality rate of hypertensive patients in hospital showed an increasing trend with the increase of age,and the mortality rate of males patients with hypertension (59.38%)was more than that of female patients(40.62%).Patients with blood pressure of 90-99/140-159 mmHg were 28 cases(7.84%),patients with blood pressure of 100-109/160-179 mmHg were 88 cases(24.56%),patients with blood pressure≥110/180 mmHg was 241 cases (67.51%).The causes of death were malignant tumors(40.62%),circulatory system diseases(38.66%),respiratory diseases(8.68%),digestive diseases(4.20%),urinary system diseases(2.80%)and others(5.04%).ConclusionThe main causes of death in hypertensive patients in hospital are malignant tumor,circulatory system disease,respiratory system disease and so on.Therefore,the clinic should pay high attention to it.
2018 Vol. 25 (5): 160-162 [Abstract] ( 183 ) HTML (23 KB)  PDF  (0 KB)  ( 98 )
163 Analyze the risk factors and nursing interventions in burned adult with sepsis
LAI Xiu-mei
ObjectiveTo analyze the influence factors and nursing interventions in burned adult with sepsis.MethodsThe clinical data about 148 burned adults with sepsis treated from February 2014 to February 2016 in our hospital was collected and patients were divided into survived group（n=99）and dead group（n=49）.According to the Logistic regression equation,the influence factors and nursing interventions for burned patients with sepsis were analyzed.ResultsThere were 49 dead cases(33.11%)and 99 survived cases(66.89%).The total burn area,third-degree burn area,initial operation time,shock,inhalation injury and MODS for survived group and dead group were significantly different(P<0.05);according to the Logistic regression equation,it was known that the risk factors of sepsis included the total burn area,third-degree burn area,nitial operation time,shock,inhalation injury and MODS(P<0.05).ConclusionThere are the multiple influence factors of burn sepsis.Meanwhile,the reasonable nursing interventions can reduce the death rate.
2018 Vol. 25 (5): 163-165 [Abstract] ( 189 ) HTML (22 KB)  PDF  (0 KB)  ( 72 )
166 Study on the effect of continuous nursing mode based on Omaha system on the postoperative quality of life in the patients with breast cancer
WEI Shu-wen
ObjectiveTo investigate the effect of continuous nursing mode via Omaha system on the postoperative quality of life in the patients with breast cancer.MethodsFrom April 2015 to June 2017,30 patients undergoing surgical treatment of breast cancer in our hospital were selected as the study object.According to the equal and random methods,the patients were divided into the conventional group and the research group,15 cases in each group.The conventional group was given routine nursing care.On the basis of routine nursing,the continuous nursing via Omaha system was given in the research group.The improvement of the quality of life in the study group and the control group after different nursing interventions were observed.ResultsAfter intervention,the quality of life,cognitive status of the disease and nursing satisfaction rate in the study group were higher than those in the control group,and the differences were statistically significant(P＜0.05）.ConclusionThe application of continuous nursing intervention by Omaha system in the clinical treatment of patients undergoing breast cancer surgery can not only improve patient satisfaction but also promote the improvement of quality of life after surgery to a certain degree.
2018 Vol. 25 (5): 166-168 [Abstract] ( 166 ) HTML (26 KB)  PDF  (0 KB)  ( 107 )
169 Effect of comprehensive nursing intervention on the knowledge，attitude and practice in the patients with senile osteoporosis
ZHANG Ling ;HUA Jin-chang; BAI Wei-ying
ObjectiveTo observe the effect of comprehensive nursing intervention on the knowledge，attitude and practice in the patients with senile osteoporosis.Methods116 patients with osteoporosis who were admitted to our hospital from May 2015 to September 2016 were selected.According to the random number table method,patients were divided into control group(n=56)and observation group(n=60).The control group was given medical treatment and traditional health education,and the observation group was given medical treatment and comprehensive nursing intervention.The mastering level of the knowledge of osteoporosis,health attitude and health practice were recorded and evaluated before intervention,after intervention and one year after intervention in both groups.ResultsAfter the intervention,the scores of osteoporosis knowledge questionnaire,the scores of osteoporosis health attitude questionnaire and the scores of osteoporosis related health practice questionnaire were compared between the two groups,and the differences were not significantly different between the two groups(P＞0.05）.One year after the intervention,the scores in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.01）.The incidence rate of fractures in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05）.ConclusionThe long-term effect of comprehensive nursing intervention on the knowledge,attitude and practice in the patients with senile osteoporosis has a more positive significance.
2018 Vol. 25 (5): 169-172 [Abstract] ( 164 ) HTML (29 KB)  PDF  (0 KB)  ( 66 )
173 Influence of nursing intervention on fall of inpatients in geriatrics department
LIN Xia
ObjectiveTo explore the influence of nursing intervention on fall of elderly patients in geriatrics department.MethodsFrom February 2015 to June 2016,1000 cases of elderly patients hospitalized in our hospital,according to the lottery method were divided into two groups,namely the control group of 500 cases and 500 cases in the experimental group.The control group was receivedroutine nursing care,while the experimental group was adopted predictive nursing intervention,observe the clinical effect of elderly patients,fall prevention knowledge before and after the nursing intervention for patients who,as well as fall prevention attitude and behavior scores,fall incidence were analyzed.ResultsBefore the intervention,there was no significant difference between the control group and the control group(P＞0.05),after the intervention,there was a significant difference between the two groups(P<0.05).ConclusionNursing care for geriatric patients has good clinical effect,can significantly improve patients fall,improve patients for fall prevention awareness,avoid dangerous incidents,it is very important to ensure the health of patients.
2018 Vol. 25 (5): 173-175 [Abstract] ( 153 ) HTML (25 KB)  PDF  (0 KB)  ( 78 )
176 Effect of postoperative early activities combined with psychological intervention on rehabilitation in patients with laparoscopic myomectomy
ZHU Ying-yan;LI Shu-ying;ZHANG Shu-juan
ObjectiveTo explore the effects of postoperative early activities combined with psychological intervention on the rehabilitation in patients with laparoscopic myomectomy.MethodsA total of 158 patients with laparoscopic myomectomy were selected from March 2015 to March 2017 and randomly divided into observation group(81 cases)and control group(77 cases)according to random number table method.Patients in the control group were receivedroutine postoperative care,while patients in the observation group were received early activity and psychological intervention on the basis of the control group.The pain score,gastrointestinal function recovery time,complication incidence and patients′satisfaction were compared between the two groups.ResultsThe pain score of the observation group was lower than that of the control group 3 days after surgery,the anus exhaust time and first feeding time were earlier than that of the control group,the incidence of postoperative complications was lower than that of the control group,the patients′satisfaction was higher than that of the control group,Differences were statistically significant(P<0.05).ConclusionPostoperative early activities combined with psychological intervention can improve postoperative patient pain,promote gastrointestinal function recovery,reduce related complications and improve patient satisfaction.
2018 Vol. 25 (5): 176-178 [Abstract] ( 188 ) HTML (26 KB)  PDF  (0 KB)  ( 62 )
179 Risk factors of bladder spasm after prostatectomy and analysis of clinical nursing measures
HUANG Xiao-huan;WANG Wen-cai
ObjectiveTo analyze the risk factors of bladder spasm after prostatectomy,explore the clinical nursing measures.Methods162 patients with benign prostatic hyperplasia from January to December 2016 in our hospital underwent transurethral resection of the prostate,patients divided into happen group (n=61)and without group (n=101)according to with or without postoperative bladder spasm,related indicators were compared between two groups,analysis of risk factors of bladder spasm,to make the clinical nursing measures.ResultsAfter analysis,group SAS was more than 50 points,low compliance bladder or(and)unstable bladder,balloon catheter injection volume 40 ml,without washing liquid heating were higher than the proportion of without group,significant difference (P<0.05);multivariate Logistic analysis showed that SAS score,low compliance and/or unstable bladder flush fluid heating,water balloon catheter was a risk factor(P<0.05).ConclusionThe prostate surgery the risk factors of bladder spasm after more clinical nursing according to the risk factors,prompting patients as early as possible recovery.
2018 Vol. 25 (5): 179-181 [Abstract] ( 158 ) HTML (24 KB)  PDF  (0 KB)  ( 52 )
182 Intervention effect of comfortable nursing in general surgery Laparoscopic surgery
KANG Ning;CHEN Chen;WU Xiang-feng;AO Bo;WANG Xue;ZHANG Qian
ObjectiveTo study and discuss the effect of comfortable nursing in general surgery laparoscopic surgery.Methods100 patients undergoing laparoscopic surgery in our hospital from January 2015 to October 2017 were selected randomly.According to the random number table method,were randomly divided into two groups,50 cases in each group.The control group and the observation group were given routine care and comfortable nursing respectively.The two groups were compared in postoperative pain score,comfort score,negative emotion score and nursing satisfaction.ResultsThe scores of pain in observation group were lower than those in control group at 8,24 and 48 h after operation(P<0.05),and their comfort scores were higher than those in control group (P<0.05).Negative emotion scores of anxiety score and depression score of the two groups were significantly lower than those before nursing(P<0.05),while negative scores of the observation group were lower than those of the control group after nursing (P<0.05).The total satisfaction rate in the observation group was 96%and that in the control group was 82%.There was significant difference between the two groups,the differences were statistically significant(P<0.05).ConclusionThe implementation of general nursing laparoscopic surgery comfort care,which can effectively reduce postoperative pain,but also effectively reduce the negative emotions，help to improve the physical and mental comfort experience,so that patients are more satisfied with the nursing services.
2018 Vol. 25 (5): 182-184 [Abstract] ( 190 ) HTML (27 KB)  PDF  (0 KB)  ( 105 )
185 Application value analysis of PDCA cycle management in preventing patients with severe high risk of tumble
LI Chun-ni;ZENG Gui-hua
ObjectiveTo study and determine the application value of PDCA cycle management intervention for patients with severe high risk of tumble.MethodsA total of 120 patients with severe high risk of tumble treated in our hospital were selected as research objects from February 2015 to January 2016.According to different management measures,they were evenly divided into control group and observation group，60 cases in each group.In the control group,conventional nursing management was applied,while in the observation group,on the basis of the conventional nursing,PDCA cycle management was added.The rate of falling,nursing satisfaction score,score of nursing management quality,and quality of life between the two groups were compared.ResultsIn the observation group,after PCDA cycle management intervention,the rate of falling down was 3.33%,lower than that in the control group accounting for 23.33%(P<0.05).The nursing satisfaction was 100.00%in the observation group,higher than that in the control group (73.33%)(P<0.05).The quality of life also had significant advantages in the observation group compared with the control group (P<0.05).ConclusionThe application of PDCA cycle management intervention to prevent severe high-risk tumble has a significant value.It can reduce the falling rate and improve the quality of life,so as to improve the nursing satisfaction,which is worthy of promotion in clinical practice.
2018 Vol. 25 (5): 185-187 [Abstract] ( 188 ) HTML (25 KB)  PDF  (0 KB)  ( 111 )
188 Comparison of rope ladder and area puncture on the influence of the functional status of autologous arteriovenous fistula
ZHANG Qiao-rong;LIU Li;ZHANG Jin-lian
ObjectiveTo study the application value of rope ladder and area puncture on the influence of the functional status of autologous arteriovenous fistula.MethodsFrom June 2015 to April 2017,96 hemodialysis patients with new internal fistula surgery were selected as research objects in our hospital.By a random number table method,they were evenly divided into research group and control group,48 cases in each group.In the research group,rope ladder was used,while in the control group,area puncture was adopted.The puncture effect of the two methods was compared.ResultsBy observing the puncture effect,the success rate of puncture and incidence of insufficiency of blood flow volume and subcutaneous hematoma were not displayed great differences(χ2=0.721,0.438,2.178,P＞0.05),but the errhysis incidence was lower in the research group (χ2=5.350,P<0.05).In the research group,the incidence of complications was 4.17%,significantly lower than that in the control group accounting for 16.67%(χ2=8.370,P<0.05).The satisfaction in the research group was 97.92%,higher than that of the control group,83.33%,with a statistical difference (χ2=12.527,P<0.05).ConclusionFor hemodialysis patients with new fistula surgery,both rope ladder and area puncture have certain application value,but few complications,high safety,and a good doctor-patient relationship maintained after rope ladder puncturing.
2018 Vol. 25 (5): 188-190 [Abstract] ( 167 ) HTML (25 KB)  PDF  (0 KB)  ( 96 )
191 Effect of rehabilitation nursing on activities of daily living in children with cerebral palsy
HE Li-xia;WANG Fang-lin;LUO Yu-hong;YANG Dan-yan;XIE Hong-mei

ObjectiveTo investigate the effect of comprehensive rehabilitation nursing on activities of daily living(ADL)in children with cerebral palsy(CP).MethodsA total of 73 with CP were recruited in our hospital from January 2013 to December.The subjects were then non-randomly allocated to a control group(n=28)who was subjected to an outpatient rehabilitation training and an intervention group(n=45)who receivedinpatient treatment.The control group was received a conventional rehabilitation training for 12 weeks,while the intervention group was received a conventional rehabilitation training as well as a comprehensive rehabilitation nursing care,which included diet,psychological,concomitant symptoms nursing and activities of daily living training.The scores of ADL were calculated and compared pre-treament and post-treatment in the two groups.ResultsThere was no difference in the scores of ADL between the two groups before treatment(P＞0.05).Compared to baseline,the scores of ADL for children with CP were significantly improved in both groups after treatment(P＜0.01）.But the scores after treatment in the intervention group were significantly higher than that of the control group(P＜0.01）.Conclusions Rehabilitation nursing intervention may be effective in improving ability of self-care and quality of life for children suffering from CP.
2018 Vol. 25 (5): 191-193 [Abstract] ( 159 ) HTML (28 KB)  PDF  (0 KB)  ( 90 )
194 Influence of community traditional Chinese medicine nursing on quality of life in elderly patients with rheumatoid arthritis
ZHONG Xi-yan;LIN Xuan;GU Man-hong
ObjectiveTo explore the influence of community traditional Chinese medicine(TCM)nursing on the quality of life(QOL)in elderly patients with rheumatoid arthritis.MethodsThe clinical data of 92 senile patients with rheumatoid arthritis in our community from January 2014 to January 2016 were collected.According to patient′s will,they were evenly divided into the experimental group and the control group,with 46 cases in each group,in the control group,the clinical conventional routine method and nursing was used,in the experimental group,community TCM nursing was applied on the basis of the control group.The patient′s QOL was assessed by SF-36 scale,and the rehabilitation effect was compared between the two groups.ResultsThe quality of life score of the experimental group was higher than that of the control group,the difference was statistically significant(t=8.694,P=0.000).The total effectiveness rate in the experimental group was 97.40%,which was significantly better than that of the control group accounting for 77.10%with a statistical difference (P<0.01).ConclusionImplementation of the community TCM nursing has a positive effect on QOL in the elderly patients with rheumatoid arthritis,and it is worthy of clinical application.
2018 Vol. 25 (5): 194-196 [Abstract] ( 157 ) HTML (26 KB)  PDF  (0 KB)  ( 60 )
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