雌二醇屈螺酮片联合坤泰胶囊治疗绝经期综合征的效果研究

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Abstract ObjectiveTo investigate the effect of Estradiol and Drospirenone Tablets combined with Kuntai Capsules in the treatment of menopausal syndrome.MethodsA total of 124 patients with menopausal syndrome treated in our hospital from January 2016 to January 2017 were selected as subjects and they were divided into two groups according to the random principle,each with 62 cases.The patients in the control group were treated with Estradiol and Drospirenone Tablets,and the patients in the study group were treated with Estradiol and Drospirenone Tablets combined with Kuntai Capsules.The changes of total cholesterol(TC),triglyceride(TG),high-density lipoprotein(HDL-C),bone density,endometrial thickness and modified Kupperman score were compared between the two groups before and after treatment.ResultsAt the time of diagnosis,the improved Kupperman score and the thickness of endometrium were not statistically significant in both groups(P>0.05).3 months after treatment,the improved Kupperman score in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05),while there was no significant difference in endometrial thickness between the two groups(P>0.05).The density of spine,femoral bone and cervical bone in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The TG and HDL-C in the study group were higher than that in the control group,and TC was lower than the control group,and the difference was statistically significant(P<0.05).ConclusionThe effect Estradiol and Drospirenone tablets combined with Kuntai Capsules in the treatment of menopausal syndrome is more favorable,which is worthy of promotion and application.

Key words： Menopausal syndrome Estradiol and Drospirenone Tablets Kuntai Capsules

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XU Xiao-xiu. Study on the effect of Estradiol and Drospirenone Tablets combined with Kuntai Capsules in the treatment of menopausal syndrome[J]. 中国当代医药, 2018, 25(5): 120-122转125.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I5/120

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