帕罗西汀联合参芪五味子颗粒治疗广泛性焦虑障碍的效果

Abstract
Figure/Table
References (15)
Related Citation (0)

Download: PDF (0 KB) HTML (28 KB)
Export: BibTeX | EndNote (RIS)

Abstract ObjectiveTo investigate the effect of Paroxetine combined with Shenqiwuweizi Granules in the treatment of generalized anxiety disorder(GAD).Methods78 cases of GAD patients treated in our hospital from March 2016 to July 2017 were randomly divided into the study group and the control group,with 39 cases in each group.The control group patients were given the Paroxetine treatment,the study group patients were treated with Shenqiwuweizi Granule on the basis of the control group.The clinical curative effect,the change of Hamilton Anxiety Scale (HAMA)score and the Pittsburgh sleep quality index(PSQI)before and after treatment,the incidence of adverse drug reactions were compared between the two groups.ResultsThe total effective rate of clinical treatment was 97.4%after 8 weeks of treatment in the study group,which was significantly higher than that of the control group of 82.1%(P＜0.05).There was no significant difference in the HAMA score and PSQI score before the treatment between the two groups(P＞0.05).The HAMA score and PSQI score of the study group decreased significantly at the 1 week after treatment,and the control group began to decrease from the second week after the treatment.The scores of HAMA and PSQI in the study group were significantly lower than those in the control group (P＜0.05).There was no statistical difference in the TESS score between the two groups of patients after treatment at different time points(P＞0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).ConclusionOn the basis of Paroxetine treatment of GAD,the combination of Shenqiwuweizi Granule can relieve anxiety and depression,and improve the treatment effect,the safety is high,patients will not produce drug dependence,it is worthy of clinical promotion and application.

Key words： Generalized anxiety disorder Paroxetine Shenqiwuweizi Granule

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	YAO Xu-dong
	LIU Fang

Cite this article:

YAO Xu-dong,LIU Fang. Effect of Paroxetine combined with Shenqiwuweizi Granule in the treatment of generalized anxiety disorder[J]. 中国当代医药, 2018, 25(5): 15-17.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I5/15

[5]	李海停.参芪五味子颗粒临床应用及安全性[J].医药前沿，2014，4（26）：261-262.
[6]	世界卫生组织.国际精神与行为障碍分型[M].10版.刘平译，北京：人民卫生出版社，1996：91-93.
[7]	徐海婷，李惠，肖泽萍.广泛性焦虑障碍药物和心理治疗的研究进展[J].临床精神医学杂志，2013，23（3）：207-209.
[8]	赵宏波，李娜，李晓娟，等.中医分型辨治广泛性焦虑障碍及病案举隅[J].环球中医药，2014，7（2）：138-140.
[9]	石敏，陶明.帕罗西汀联合认知行为疗法治疗广泛性焦虑障碍的临床研究[J].中国现代医生，2015，53（32）：90-92.
[1]	余灿清，吕筠，陈怡平，等.中国10地区30～79岁成人广泛性焦虑障碍的相关因素[J].中国心理卫生杂志，2015，29（8）：581-586.
[2]	张开元，施剑飞，唐光政，等.帕罗西汀联合喹硫平治疗广泛性焦虑障碍的疗效与安全性[J].中国临床药理学杂志，2014，30（6）：508-510.
[3]	沈鑫华，沈仲夏.广泛性焦虑障碍的治疗进展[J].医学与哲学，2013，34（4）：15-19.
[4]	王永军，陈大方，王传跃.九味镇心颗粒治疗广泛性焦虑障碍多中心随机双盲对照试验[J].中国心理卫生杂志，2013，27（2）：126-131.
[10]	杨杰霖，李鹤展.广泛性焦虑障碍的病因机制与治疗综述[J].中外医学研究，2015，13（17）：154-157.
[11]	熊航，王玉来，郭蓉娟，等.基于现代文献的广泛性焦虑障碍辨证分型分析[J].中医药信息，2014，31（2）：27-30.
[12]	张家宁，李文涛.广泛性焦虑症的中医认识及研究现状[J].中西医结合心脑血管病杂志，2016，14（12）：1360-1363.
[13]	洪艳，何忠梅，王国丽，等.参芪五味子片对神经系统的药理作用及临床研究[J].吉林中医药，2014，34（8）：842-844.
[14]	曾志兰，周建寅.参芪五味子片治疗慢性失眠症临床观察[J].亚太传统医药，2014，10（19）：106-107.
[15]	宋日新，姜国红，常宝忠，等.参芪五味子颗粒治疗慢性失眠症的效果及安全性观察[J].中国综合临床，2015，31（10）：931-933.