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| CIK cells in the treatment of digestive system tumors |
| SUN Jie1 WANG Xing1 WANG Cui-fang1 ZHANG Chun-yang2 |
1.Department of Pathology,Affiliated Central Hospital of Shenyang Medical University,Liaoning Province,Shenyang 110024,China;
2.DepartmentofEmergency,Affiliated CentralHospitalofShenyangMedicalUniversity,Liaoning Province,Shenyang 110024,China |
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Abstract ObjectiveTo investigate the therapeutic effect of cik cells on digestive system tumors.MethodsFrom January 1,2012 to February 25,2014,100 cases of digestive system tumor patients in our hospital were selected as the research objects,according to the differences in treatment measures of digestive system tumor patients were divided into control group,experimental group,50 cases in each group.The control group was treated with palliative treatment,while the experimental group was treated with CIK cells.The difference of treatment results between the two groups were compared.ResultsThe levels of CD3+and CD3+CD8+in the experimental group were significantly higher than those in the control group (P<0.05).There was no significant difference between the two groups in OS and PFS (P>0.05).The quality of life of the experimental group was significantly better than that of the control group(P<0.05).The tumor markers(CA 724,CA199)in the experimental group were significantly lower than those in the control group (P<0.05).There was no significant difference in the level of peritoneal effusion between the two groups (P>0.05).ConclusionPatients with digestive system tumors receiving CIK cell therapy can improve their immunity,living standards and tumor markers,but there is no significant improvement in survival time,peritoneal effusion and other aspects.
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