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2021 Vol. 28, No. 20 Published: 2021-07-18

	4	Clinical effect of Amiodarone Injection in the treatment of acute heart failure and tachyarrhythmia
		LIANG Jin-feng DONG Qi LIU Lai-bing HE Hao-jiang LIU Wu-peng▲
		Objective To analyze the clinical effect of Amiodarone Injection in the treatment of acute heart failure and tachyarrhythmia.Methods A total of 70 patients with acute heart failure complicated with tachyarrhythmia admitted to the Department of Cardiology, Baiyun Hospital Affiliated to Guizhou Medical University from October 2018 to October 2020 were selected as the research subjects.According to the random number table method, they were divided into study group and control group, with 35 patients in each group.The control group was treated with routine treatment and the study group was treated with Amiodarone Injection.The comprehensive effectiveness rate and physical indicators before and after treatment including diastolic blood pressure (DBP), systolic blood pressure (SBP), mean arterial pressure (MAP), heart rate (HR), and dynamic echocardiographic indicators including corrected QT interval (QTc) and QT dispersion (QTd), and cardiac function indicators including left ventricular systolic dimension (LVDS), left ventricular diastolic diameter (LVDD), left ventricular function (LVEF), cardiac index (CI), and 6-min walking distance of the two groups were compared.Results The comprehensive effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P＜0.05).After treatment, SBP, MAP and HR in the study group were lower than those in the control group, while DBP was higher than those in the control group, with statistical significance (P＜0.05).After treatment, QTC of the study group was higher than that of the control group, and QTD of the study group was lower than that of the control group, the differences were statistically significant (P＜0.05).After treatment, the LVEF and CI of the study group were higher than those of the control group, and the 6-min walking distance was greate than that of the control group, with statistical significance (P＜0.05).After treatment, LVDS and LVDD in the study group were lower than those in the control group, and the differences were statistically significant (P＜0.05).Conclusion The addition of Amiodarone Injection in the clinical treatment of patients with acute heart failure and tachyarrhythmia can exert a synergistic effect and enhance the treatment effectiveness.Meanwhile, it can greatly improve the physical indicators, dynamic echocardiographic indicators and cardiac function, with a considerable overall treatment effect.
		2021 Vol. 28 (20): 4-007 [Abstract] ( 46 ) HTML (37 KB) PDF (0 KB) ( 8 )

	8	Oxidation of human neuroblastoma cells treated with rotenone
		ZHANG Ping1 SHAO Liang2
		Objective To investigate the expression of intracellular oxides and antioxidants in human neuroblastoma cells (SH-SY5Y) effected by rotenone.Methods The cells were divided into normal group and rotenone group according different treatment after two days of conventional fetal bovine serum culture.The rotenone group was divided into five subgroups according to the concentration gradient of 25, 50, 100, 200, 500, 1000, 2000 nM (nM: nmol/L).The morphological changes of the cells were observed by light microscope and the survival and growth of the cells were detected by MTT colorimetry.Flow cytometry was used to observe the changes of DCFH-DA in the cells after rotenone intervention, and enzyme-linked immunosorbent assay was used to determine the activity of superoxide dismutase(SOD) and lipid peroxidation.Results It was confirmed that the cell viability of SH-SY5Y was dose-dependent with the intervention concentration of rotenone by MTT assay and light microscopy detection.The concentration of 500 nM rotenone could induce oxidative stress injury without excessive cell death, while the growth of cells almost stopped when 2000 nM rotenone was added into the medium.Flow cytometry and enzyme-linked immunosorbent assay showed that DCFH-DA staining of SH-SY5Y cells treated with 500 nM rotenone increased the level of oxidative stress, decreased the activity of SOD and increased the level of oxide lipid peroxidation products (TBARS).Conclusion Rotenone could regulate down of SOD activity in SH-SY5Y cells, increase the production of lipid peroxidation and increase the level of oxidative stress.The cell viability of SH-SY5Y was positively correlated with the concentration of rotenone.The higher the concentration, the more cell death.
		2021 Vol. 28 (20): 8-011 [Abstract] ( 39 ) HTML (36 KB) PDF (0 KB) ( 7 )

	12	Study on the effect mechanism of scutellarin in the occurrence and development of colon cancer
		LI Yuan-zhi1 WANG Jun-dong2 YUE Chao-chi1 LONG Qing1 LI Jun1
		Objective To explore the effect mechanism of scutellarin in the occurrence and development of colon cancer.Methods MTT, flow cytometry, wound healing, Transwell chamber and mouse tumor-bearing test were carried out to determine the effect of scutellarin on the proliferation, apoptosis, migration, invasion and tumorigenesis of colon cancer T84 cells respectively.Western Blot was performed to assess the protein levels of Bcl-2/Bax, caspase3/9, ERK1/2,p-ERK1/2, epidermal growth factor receptor (EGFR), c-myc and c-fos after T84 cells were treated with scutellarin.Immunofluorescence technique was used to evaluate the subcellular location of ERK1/2 in T84 cells after scutellarin treatment.Results Scutellarin treatment inhibited the proliferation, migration, invasion and tumorigenesis of T84 cells,and induced cell apoptosis;scutellarin treatment decreased the expression of p-ERK1/2, EGFR, c-myc and c-fos, while translocated ERK1/2 from nuclear to cytoplasm.Inhibition of cell proliferation and tumorigenesis and enhancement of cell apoptosis caused by scutellarin were all weakened when EGFR was up-regulated in T84 cells.All differences were statistically significant (P＜0.05).Conclusion Scutellarin represses the progression of colon cancer through inhibiting the activation of EGFR/ERK1/2 signaling pathway.
		2021 Vol. 28 (20): 12-16转20 [Abstract] ( 47 ) HTML (41 KB) PDF (0 KB) ( 6 )

	17	Application comparison of total internal suture and internal and external suture in repair of posterior angle of medial meniscus
		WANG Wen WANG Min▲ QIN Sheng-nan LIANG Shao-hua CHEN Liang
		Objective To compare the effect of total internal suture repair and internal and external suture repair in the treatment of medial meniscus posterior horn injury.Methods The clinical data of 62 patients with medial meniscus posterior angle tear who underwent surgical treatment from June 2014 to February 2018 were retrospectively analyzed.According to the suture repair plan, they were divided into the total internal suture group (35 cases) and the internal and external suture group (27 cases).The internal suture group was treated with internal suture repair, and the internal and external suture group was treated with internal and external suture repair.The clinical healing rate, magnetic resonance imaging (MRI) healing rate, intraoperative operation time, pain before and after surgery, knee function before and after surgery, and complications were compared between the two groups.Results The intraoperative operation time of the total internal suture group was shorter than that of the internal and external suture group, the clinical healing rate and MRI healing rate were higher than those of the internal and external suture group, the differences were statistically significant (P＜0.05).Before the treatment, the visual analogue scale (VAS) score and the international knee documentation committee knee evaluation form (IKDC) score were compared between the two groups of patients, there were no significant differences (P＞0.05).The VAS score after treatment in two groups was lower than that before treatment, and the IKDC score after treatment was higher than that before treatment, the differences were statistically significant (P＜0.05).The VAS score of the total internal suture group was lower than that of the internal and external suture group,the difference was statistically significant (P＜0.05).Compared with the internal and external suture group, the IKDC score was not statistically significant (P＞0.05).There were no cases of vascular nerve injury, postoperative infection, or joint stiffness in the two groups.Conclusion Compared with internal and external suture in the treatment of posterior horn injury of the medial meniscus, total internal suture repair has better healing, shorter operation time and less postoperative pain.Therefore, it could be used as the preferred repair method and promoted.
		2021 Vol. 28 (20): 17-20 [Abstract] ( 42 ) HTML (38 KB) PDF (0 KB) ( 6 )

	21	Analysis of risk factors for failure of high-flow nasal cannula oxygen therapy for severe pneumonia in children
		ZHENG Li-ling ZHENG Wei-da YANG Xiao-yun
		Objective To explore the risk factors for failure of high-flow nasal cannula oxygen therapy（HFNC）for severe pneumonia in children.Methods A total of 118 children with severe pneumonia treated with HFNC admitted to the Pediatric Intensive Care Unit (PICU) of Zhangzhou Hospital Affiliated to Fujian Medical University from January 2019 to February 2020 were retrospective analyzed.They were divided into success group (n=80) and failure group (n=38) according to whether HFNC was successfully withdrawn.The general data, arterial blood gas indexes, incidence of basic diseases and incidence of complications of the two groups were compared.Multivariate Logistic regression was used to analyze the risk factors of HFNC withdrawal failure in children with severe pneumonia.Results The failure rate of HFNC was 32.20% in 118 children with severe pneumonia.The total hospital stay and PICU stay in the failure group were longer than those in the successful group, the differences were statistically significant (P＜0.05).The white blood cell and partial pressure of carbon dioxide in the failed group were higher than those in the successful group, and the oxygenation index was lower than that in the successful group, the differences were statistically significant (P＜0.05).The proportions of heart disease, malnutrition, premature infant and other basic diseases in the failure group were higher than those in the success group, the differences were statistically significant (P＜0.05).The proportions of complicated heart failure and ventilator-associated pneumonia in the failure group were higher than those in the successful group,and the differences were statistically significant (P＜0.05).The results of multivariate Logistic regression analysis indicated that combined heart failure (β=1.639, OR=5.148, 95%CI=1.424-18.611), preterm infants (β=1.229, OR=3.418,95%CI=0.535-21.846) and long total hospital stay (β=0.164, OR=1.178, 95%CI=1.039-1.336) were risk factors for failure of HFNC (P＜0.05).High oxygenation index on admission (β=-0.015, OR=0.985, 95%CI=0.975-0.996) was the protective factors for HFNC failure (P＜0.05).Conclusion HFNC can be used for the treatment of severe pneumonia in children with pediatric intensive care unit, but cases of failure still exist.For children with underlying diseases such as premature infants or combined with heart failure, it is a high-risk factor for HFNC withdrawal failure, and will increase the total hospital stay.At admission, a preliminary judgment can be made by comprehensive analysis of related medical history and clinical manifestations, combined with blood gas and oxygenation index, and then select the appropriate respiratory support mode, so that the children can get better treatment.
		2021 Vol. 28 (20): 21-25 [Abstract] ( 39 ) HTML (47 KB) PDF (0 KB) ( 6 )

	26	Clinical effect of Jianwei Xiaowei Decoction on chronic atrophic gastritis
		ZHOU Ying WU Zi-qiang
		Objective To investigate the clinical effect of Jianwei Xiaowei Decoction on chronic atrophic gastritis.Methods A total of 80 patients with chronic atrophic gastritis admitted to the Shaoguan Traditional Chinese Medicine Hospital from January 2019 to September 2020 were selected as the research subjects and divided into treatment group and control group according to random number table method, with 40 patients in each group.The treatment group was given Jianwei Xiaowei Decoction treatment, and the control group was given Weifuchun Tablets treatment, both groups were treated for 3 months.The clinical efficacy of traditional Chinese medicine (TCM) syndromes, pathological changes of gastric mucosa and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of TCM syndrome treatment in the treatment group was higher than that in the control group, the difference was statistically significant (P＜0.05).After treatment, the total pathological scores of both groups were lower than before treatment, and the treatment group was lower than the control group, the differences were statistically significant(P＜0.05).The total effective rate of gastroscopy and pathology in the treatment group was higher than that in the control group after treatment, the difference was statistically significant (P＜0.05).There were no obvious adverse reactions in both groups during treatment.Conclusion Jianwei Xiaowei Decoction has a good clinical effect on chronic atrophic gastritis, and can promote gastric mucosa repair to a certain extent, improve the atrophy of gastric mucosa and intestinal metaplasia, less adverse reactions, worthy of clinical application.
		2021 Vol. 28 (20): 26-29 [Abstract] ( 57 ) HTML (37 KB) PDF (0 KB) ( 6 )

	30	Research progress on anti-tumor mechanism of Polysaccharide
		YIN Zhe1，2 CAI Dan-zhao1，2 CHEN Hong-tao3▲
		Polysaccharide is a kind of high macromolecular compound with various structure and molecular weight.It is also one of the four basic substances that have biological activity and constitute life activities.Polysaccharide has a wide range of pharmacological effect.It not only participates in regulating the body′s metabolism and immune function,but also has anti-tumor, anti-virus, anti-oxidation, anti-aging, and hypoglycemic effect.The research of anti-tumor drugs has faced great challenges in recent years.Polysaccharide has been widely concerned and studied by researchers because of its significant anti-tumor activity, high efficiency, low toxicity, wide source and low price.This study reviews the anti-tumor effect and mechanism of polysaccharides, to provide a theoretical basis and literature for the subsequent preparation development, clinical research and application.
		2021 Vol. 28 (20): 30-34 [Abstract] ( 40 ) HTML (53 KB) PDF (0 KB) ( 7 )

	35	Research progress on the relationship between neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and rheumatic immune disease
		LI Ping SUN Yu-wei▲ JIAO Hong-mei ZHANG Miao REN Dan-dan
		The pathogenesis of rheumatic immune diseases is complicated and the incidence is high, and it is easy to recur.Inflammatory response plays a very important role in rheumatic immune diseases.In recent years, researchers at home and abroad have discovered two inflammatory indicators: neutrophil-to-lymphocyte ratio (NLR) and platelet-tolymphocyte ratio (PLR), which are easy to measure, fast to reproduce, and relatively economical.Initial studies have shown that NLR and PLR are related to the disease activity and prognosis in patients with cardiovascular diseases or malignant tumors.Recent studies have found that NLR and PLR are related to the acute phase activity of rheumatic immune diseases and can predict the risk of complications related to rheumatic immune diseases.This article reviews the research progress of NLR、PLR and rheumatic immune disease.
		2021 Vol. 28 (20): 35-38 [Abstract] ( 39 ) HTML (38 KB) PDF (0 KB) ( 7 )

	39	Research progress of insomnia treated from the five internal organs
		LIN Jia-ming YAO Bao-nong WU Yan-li LIN Li-cheng HUANG Xue-yan
		Insomnia is a common type of sleep disorder.With the incidence rising gradually, insomnia affects the patients′ physical and mental health and quality of life seriously.Chinese Medicine believes that insomnia is closely related to the imbalance of Yin and Yang, imbalance of Ying and Wei，and dysfunction of viscera.Chinese medicine in the treatment of insomnia has unique advantage and efficacy.Researchers contend that the five internal organs and insomnia are closely related.The study aims to explore the physiological function and dialectical treatment of heart, liver,spleen, lungs and kidneys and its relationship with the insomnia treatment through takeing “the Five Internal Organs”as the entry point.It is expected to provide a theoretical reference for the diagnosis and treatment of insomnia in Chinese medicine.
		2021 Vol. 28 (20): 39-43 [Abstract] ( 52 ) HTML (49 KB) PDF (0 KB) ( 8 )

	44	Analysis of the value of Xpert MTB/RIF UItra detection of pleural effusion in the clinical diagnosis of tuberculous pleurisy
		CHEN Yan-ling ZHONG Yi-kai HUANG Jian
		Objective To investigate the value of Xpert MTB/RIF UItra (referred to as Xpert UItra) detection of pleural effusion in the clinical diagnosis of tuberculous pleurisy.Methods From June 2018 to June 2020, 120 patients with suspected tuberculosis pleurisy admitted to Jiangxi Chest Hospital were selected as the research subjects.The pleural effusion of all patients was collected.According to pathological examination as the gold standard, the patients were divided into confirmed group (58 cases), suspected group (42 cases) and non-tuberculosis group (20 cases).Xpert MTB/RIF (referred to as Xpert) and Xpert UItra were used to detect the pleural effusion of patients in the three groups respectively, and the sensitivity, specificity and accuracy of the two detection methods were discussed.Results In the confirmed group, the positive rate of Xpert UItra test was 96.55%, which was higher than that of Xpert (82.76%), with statistical difference (P＜0.05).In the suspected diagnosis group, the positive rate of Xpert UItra detection was 66.67%,which was higher than that of Xpert (45.24%), with statistical difference (P＜0.05).In the non-tuberculosis group, the positive rate of Xpert UItra detection was 5.00%, lower than that of Xpert (30.00%), and the difference was statistically significant (P＜0.05).The sensitivity, specificity and accuracy of Xpert UItra for tuberculous pleurisy were 96.50%,95.00% and 96.15%, which were all higher than those of Xpert (82.76%, 70.00% and 79.49%), and the differences were statistically significant (P＜0.05).Conclusion In the diagnosis of tuberculous pleurisy, the use of Xpert Uitra for the diagnosis of pleural effusion in patients has high accuracy, sensitivity and specificity, and has high diagnostic value.
		2021 Vol. 28 (20): 44-46转50 [Abstract] ( 44 ) HTML (30 KB) PDF (0 KB) ( 7 )

	47	Influence of postural intervention on intraoperative comfort in patients undergone ERCP and EST operations
		JIANG Xiao-xia DENG Shu-hong▲
		Objective To explore the application effect of intraoperative postural intervention in patients with endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (EST).Methods A total of 108 patients who underwent ERCP+EST surgical treatments in the Fourth Affiliated Hospital of Nanchang University from June 2018 to June 2020 were selected as the research subjects.They were divided into the control group (54 cases)and the observation group(54 cases)by the random number table method.In the control group,routine intervention was used,and in the observation group, postural intervention was added on the basis of the control group.The general comfort questionnaire(GCQ) scores before surgery and 6 h after surgery were compared in the two groups.The surgical operations such as preoperative posture arrangement time, operation time, and postoperative hospital stay were recorded.The incidence of complications in the two groups was calculated and compared.Results The GCQ score of the observation group after intervention was higher than that of the control group, and the difference was statistically significant (P＜0.05).In the observation group, the preoperative posture arrangement time, operation time, and postoperative hospital stay were shorter than those in the control group, and the differences were statistically significant (P＜0.05).The total incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant (P＜0.05).Conclusion Postural intervention for patients during ERCP and EST surgery can improve patient comfort, reduce the risk of posture-related complications, which will help to promote postoperative recovery.
		2021 Vol. 28 (20): 47-50 [Abstract] ( 33 ) HTML (32 KB) PDF (0 KB) ( 7 )

	51	Application of zusanli acupoint injection in immune regulation of patients with sepsis
		WEI Qing-lan LIU Ling-ling ZHU Man-gui ZHONG Jian
		Objective To observe the effect of normal saline injection at zusanli acupoint on immune indexes of patients with sepsis.Methods A total of 40 sepsis patients admitted to the intensive care unit (ICU) of Shunde Hospital of Guangzhou University of Traditional Chinese Medicine from December 2019 to January 2021 were selected as the research subjects.They were divided into observation group and control group by random number table method, with 20 patients in each group.All the patients were given standard treatment according to sepsis guidelines, the observation group was injected with normal saline at zusanli acupoint once a day for 7 days on the basis of control group.The white blood cell count (WBC) and absolute lymphocyte value (LYM) of two groups were compared before and after treatment.Immune indexes (total number of T cells[CD3+], number of helper T cells[CD4+], ratio of helper T cells to inhibitory T cells[CD4+/CD8+]), acute physiology and chronic health status scoring system Ⅱ(APACHEⅡ) scores were compared between two groups before and after treatment.The outcomes of the two groups were compared.Results The levels of LYM, CD3+, CD4+and CD4+/CD8+in the two groups after 7 d of treatment were higher than those before treatment, with statistically significant differences (P＜0.05).LYM, CD3+, CD4+, CD4+/CD8+after 7 days of treatment in observation group were higher than those in control group,with statistically significant differences(P＜0.05).The WBC and APACHEⅡscores of the two groups after 7 d of treatment were lower than those before treatment, with statistically significant differences(P＜0.05).There were no significant differences in WBC and APACHEⅡscores between the two groups after 7 days of treatment (P＞0.05).There was no significant difference in 28-day mortality between the two groups (P＞0.05).Conclusion Zusanli acupoint injection of normal saline can improve the immune indexes of patients with sepsis, and it has certain application value in the treatment of sepsis.
		2021 Vol. 28 (20): 51-54 [Abstract] ( 45 ) HTML (41 KB) PDF (0 KB) ( 8 )

	55	Influence of Anshen Foot Bath Prescription combined with Foot Bottom Massage on sleeping quality of the patient with insomnia
		CHEN Wei-wei CHEN Yuan-ting WANG Li-jun
		Objective To explore the influence of Anshen Foot Bath Prescription combined with Foot Bottom Massage on sleeping quality of the patient with insomnia.Methods A total of 60 patients with insomnia admitted to Shenzhen Hospital of Guangzhou University of Chinese Medicine from July 2019 to July 2020 were selected as the research subjects, which were divided into the control group (n=30) and the observation group (n=30) according to random number table method.The control group was treated with conventional treatment, and the observation group was treated with Anshen Foot Massage and Foot Bottom Massage on the basis of the control group for a month.The clinical efficacy,Pittsburgh sleep quality index (PSQI) score, Self-Rating Anxiety Scale (SAS) score and Self-Rating Depression Scale(SDS) score were compared between the two groups.Results The total effective rate of the clinical efficacy in the observation group was 93.33%, which was higher than that in the control group (70.00%), with statistically significant difference (P＜0.05).Before treatment, there were no significant differences in sleep latency time, sleep quality, actual sleep time, sleep efficiency and PSQI scores between the two groups (P＞0.05).The sleep latency time of the two groups after treatment was shorter than that before treatment, the sleep quality score and total PSQI score of the two groups after treatment were lower than those before treatment, the actual sleep time of the two groups after treatment was longer than that before treatment, and the sleep efficiency of the two groups after treatment was higher than that before treatment, the differences were statistically significant (P＜0.05).The sleep latency time of the observation group after treatment was shorter than that of the control group, the sleep quality score and total PSQI score of the observation group after treatment were lower than those of the control group, the actual sleep time of the observation group after treatment was longer than that of the control group, and the sleep efficiency of the observation group after treatment was higher than that of the control group, the differences were statistically significant (P＜0.05).Before treatment, there was no significant difference in the SAS score and SDS score between the two groups (P＞0.05).After treatment, the SAS score and SDS score in the observation group were lower than those in the control group, with statistical significance (P＜0.05).Conclusions Anshen Foot Bath Prescription combined with Foot Bottom Massage can effectively improve the sleep quality and sleep efficiency of insomnia patients.
		2021 Vol. 28 (20): 55-58 [Abstract] ( 47 ) HTML (37 KB) PDF (0 KB) ( 6 )

	59	Effect of Agomelatine in the treatment of patients with alcohol dependence complicated with depression
		ZHONG Hai-long
		Objective To explore the effect of Agomelatine in the treatment of patients with alcohol dependence complicated with depression.Methods A total of 100 patients with alcohol dependence withdrawal complicated with depressive symptoms who came to the Third People′s Hospital of Ganzhou for treatment from March 2019 to July 2020 were selected as the study subjects, and they were divided into the study group (50 cases) and the control group (50 cases) according to the simple randomization method.The study group was treated with Agomelatine while the control group was treated with Fluoxetine.The alcohol use disorder, negative emotions, sleep quality and adverse drug reactions were compared between the two groups.Results After 2, 4 and 8 weeks of treatment, the Alcohol Use Disorders Identification Test (AUDIT) score, the Hamilton anxiety scale (HAMA) score, the Hamilton depression scale (HAMD) score,the Pittsburgh sleep quality index (PSQI) score and the incidence rate of adverse drug reactions of the study group were lower than those of control group, and the differences were statistically significant (P＜0.05).Conclusion Agomelatine has a good efficacy in the treatment of patients with alcohol dependence complicated with depression.It can improve the sleep status, relieve mood disorders and reduce the incidence rate of adverse reactions.Thus it is worthy of clinical promotion and application.
		2021 Vol. 28 (20): 59-61转65 [Abstract] ( 62 ) HTML (34 KB) PDF (0 KB) ( 9 )

	62	Application effect of nasal high flow oxygen therapy in acute attack of bronchial asthma

		Objective To explore the application effect of nasal high flow oxygen therapy in acute attack of bronchial asthma.Methods Fifty patients with acute attack of bronchial asthma who were admitted to the Second Affiliated Hospital of Gannan Medical College from August 2019 to November 2020 were selected as the research objects, and they were divided into the control group (25 patients) and the observation group (25 patients) according to the random number table method.The control group was given drug therapy, and observation group was given nasal high flow oxygen therapy on the basis of control group.The treatment effect and the incidence of complications were compared between the two groups.The pulmonary function indexes before treatment and 1 week after treatment were compared between the two groups.Results The total effective rate of the observation group (96.00%) was higher than that of the control group (64.00%), and the difference was statistically significant (P＜0.05).The forced expiratory volume in 1 second(FEV1), peak expiratory flow (PEF) and FEV1/forced vital capacity (FVC) in the observation group were higher than those in the control group at 1 week of treatment, and the differences were statistically significant (P＜0.05).There was no significant difference in the total incidence of complications between the two groups (P＞0.05).Conclusion For patients with acute attack of bronchial asthma, nasal high flow oxygen therapy has good effect, fewer complications, can significantly improve lung function, and has outstanding application value.
		2021 Vol. 28 (20): 62-65 [Abstract] ( 39 ) HTML (34 KB) PDF (0 KB) ( 8 )

	66	Analysis of sleep structure and its influencing factors in elderly patients with insomnia
		ZHENG Yu-ling OU Hai-yan▲ XIONG Can-biao YUAN Yu-yan WU Ao-wen
		Objective To explore the analysis of sleep structure and its influencing factors including gender, comorbidity of underlying diseases, and to analyze the influencing factors such as gender, combination of basic diseases, anxiety and/or depression.Methods From January 2012 to December 2019, 300 elderly patients with insomnia as the main complaint in Dongguan Seventh People′s Hospital were selected as the research subjects.All patients were monitored by polysomnography, and sleep structure, gender, underlying diseases, anxiety, depression and other indicators were collected.Results 40.7% of patients had abnormal sleep latency, 61.0% had abnormal sleep efficiency, 70.3% had abnormal arousal index, and 28.7% had abnormal total sleep time.Conclusion The combination of underlying diseases,anxiety and depression has an impact on the structural parameters of elderly patients with insomnia, and targeted intervention measures should be taken for such groups.
		2021 Vol. 28 (20): 66-68 [Abstract] ( 40 ) HTML (31 KB) PDF (0 KB) ( 6 )

	69	Application of closed circulation irrigation and drainage in elderly patients with chronic subdural hematoma
		ZHANG Jin-shi WEI Wen-jin HUANG Yu LI Wei TANG Tao
		Objective To investigate the application value of closed circulation irrigation and drainage in the treatment of chronic subdural hematoma (CSDH) in the elderly.Methods A total of 94 elderly patients with chronic subdural hematoma who were admitted to Ganzhou People′s Hospital from January 2019 to August 2020 were selected as the research objects.According to the random number table method, they were divided into study group (47 cases) and control group (47 cases).Both groups were treated with cranial drilling hematoma drainage.The study group was given closed-loop irrigation intervention, and the control group was given traditional open irrigation and drainage intervention.The efficacy, early postoperative recovery and prognostic effects of the two groups were compared.Results The efficacy of CSDH cases in the study group was higher than that in the control group, and the recurrence rate was lower than that in the control group, with statistical significance (P＜0.05).The residual hematoma volume and subdural volume in the study group were less than those in the control group on the first day after surgery, and the symptom improvement time was shorter than that in the control group, with statistical significance (P＜0.05).At the last follow-up,the chinese stroke scale (CSS) score of both groups was lower than that before treatment, and the BI index was higher than that before treatment, with statistical significance (P＜0.05), and the CSS score of the study group was lower than that of the control group, the BI index of the study group was higher than that of the control group, with statistical significance (P＜0.05).Conclusion In the elderly chronic subdural hematoma drilling hematoma drainage to carry out the intervention of closed circulation flushing drainage, is helpful to improve the efficacy, reduce the risk of recurrence of hematoma, promote postoperative recovery of patients, improve the prognosis.
		2021 Vol. 28 (20): 69-72 [Abstract] ( 39 ) HTML (34 KB) PDF (0 KB) ( 7 )

	73	Application value and safety of leukocyte filtration transfusion technology in clinical blood transfusion
		JIAO Dong-mei
		Objective To explore and analyze the application value and safety of leukocyte filtration transfusion technology in clinical blood transfusion.Methods From June 2018 to May 2020, 80 blood transfusion patients admitted to Baicheng Hospital of Jilin Province were selected as the research objects, and they were divided into the observation group (40 cases) and the control group (40 cases) according to the computer random number table method.The observation group was treated with leukocyte filtration transfusion, while the control group was treated with conventional blood transfusion.The indexes of blood platelet, hemoglobin and white blood cell, temperature rise during blood transfusion, fibrinogen (FIB), prothrombin time (PT), activated partial thromboplastin time (APTT) and the incidence of adverse reactions were compared between the two groups.Results The levels of blood platelet, hemoglobin and white blood cell indexes of the observation group were lower than those of the control group, the differences were statistically significant (P＜0.05).The temperature rise and during blood transfusion and FIB of the observation group were lower than those of the control group, the level of PT of the observation group was shorter than that of the control group, the level of APTT of the observation group was longer than that of the control group, the differences were statistically significant (P＜0.05).The incidence of blood transfusion adverse reactions in the observation group (5.00%) was lower than that of the control group (20.00%), and the difference was statistically significant (P＜0.05).Conclusion Leukocyte filtration transfusion technology can improve the blood quality of patients with blood transfusion, prevent the risk of adverse reactions in the process of blood transfusion, and improve the therapeutic effect of blood transfusion, which is worthy of application.
		2021 Vol. 28 (20): 73-75 [Abstract] ( 39 ) HTML (31 KB) PDF (0 KB) ( 6 )

	76	Clinical effect of nebulized inhalation of Budesonide in the treatment of acute exacerbation of chronic obstructive pulmonary disease
		LIN Da-yong
		Objective To investigate the clinical effect of nebulized inhalation of Budesonide in the treatment of acute exacerbation of chronic obstructive pulmonary disease.Methods From January 2018 to December 2019, 100 patients with acute exacerbation of chronic obstructive pulmonary disease in Liaoning Health Industry Group Iron Coal General Hospital were selected as subjects.The patients were divided into control group(50 cases)and observation group(50 cases) by random number table method.Ambroxol Hydrochloride was given in the control group, and on the basis of control group, observation group was additionally treated with nebulized inhalation of Budesonide.The clinical symptom remission time, pulmonary function indexes, arterial oxygen indexes and the total effective rate of treatment were compared between the two groups.Results The total effective rate of observation group was higher than that in the control group, and the difference was statistically significant (P＜0.05).After treatment, the forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and peak expiratory flow (PEF) of the observation group were higher than those in the control group, the differences were statistically significant (P＜0.05);and the symptoms of chronic obstructive pulmonary disease (CAT) score of the observation group was lower than that of the control group, the difference was statistically significant (P＜0.05).After treatment, the arterial partial pressure of oxygen (PaO2) in the observation group was higher than that in the control group, the difference was statistically significant (P＜0.05).The arterial partial pressure of carbon dioxide (PaCO2) in observation group was lower than that in the control group, and the difference was statistically significant (P＜0.05).The asthma relief time, rale disappearance time and cough relief time in observation group were all shorter than those in the control group, with statistically significant differences (P＜0.05).Conclusion Nebulized inhalation of Budesonide has a good clinical effect in the treatment of acute exacerbation of chronic obstructive pulmonary disease, which can effectively improve the treatment efficiency of patients, improve the pulmonary function indexes and arterial oxygen indexes of patients, and shorten the remission time of clinical symptoms, which has important clinical research value.
		2021 Vol. 28 (20): 76-78转82 [Abstract] ( 39 ) HTML (36 KB) PDF (0 KB) ( 9 )

	79	Value of combined detection of anti-cyclic citrate polypeptide antibody,rheumatoid factor and C-reaction protein in the diagnosis of rheumatoid arthritis
		MA Shu-fang1 HAN Xiao-jiao1 KANG Yin-hong2
		Objective To analyze the value of anti-cyclic citrulline polypeptide (CCP) antibody, rheumatoid factor (RF)and C-reaction protein (CRP) combined detection in the diagnosis of rheumatoid arthritis.Methods A total of 107 patients with suspected rheumatoid arthritis admitted to the Fourth Central Hospital of Baoding City from January 2018 to November 2020 were selected.Combined with clinical manifestations, laboratory examination and imaging examination results, it was comprehensively determined as "gold standard".The sensitivity and specificity of different detection methods were compared respectively.Among them, 98 cases of rheumatoid arthritis patients admitted to the Fourth Central Hospital of Baoding City from January 2018 to November 2020 were selected as group A, and 106 cases of non-rheumatoid arthritis patients with autoimmune diseases admitted to the Fourth Central Hospital of Baoding City during the same period were selected as group B.A total of 100 persons receiving physical examination in the Fourth Central Hospital of Baoding City during the same period were selected as group C.Anti-CCP antibody alone detection,RF alone detection, CRP alone detection, anti-CCP antibody+RF+CRR combined detection were carried out for all personnel.The detection results of anti-CCP antibody, RF and CRP levels in the three groups were compared.Results The levels of anti-CCP antibody, RF and CRP in groups A and B were higher than those in group C, and the differences were statistically significant (P＜0.05).The levels of anti-CCP antibody, RF and CRP in group A were higher than those in group B, and the differences were statistically significant (P＜0.05).The sensitivity and specificity of anti-CCP antibody+RF+CRP combined detection were higher than those of anti-CCP antibody alone detection, RF alone detection and CRP alone detection, and the differences were statistically significant (P＜0.05).Conclusion The anti-CCP antibody+RF+CRR combined detection in patients with rheumatoid arthritis has high sensitivity and specificity, which plays a positive role in the diagnosis and treatment of the disease, and is worthy of clinical application.
		2021 Vol. 28 (20): 79-82 [Abstract] ( 42 ) HTML (33 KB) PDF (0 KB) ( 8 )

	83	Impact of family-based health management on the knowledge，attitude，belief and practice model of stroke high-risk populations
		ZHANG Ya-mei WANG Lu-ya
		Objective To explore the impact of family-based health management on the knowledge, attitude, belief and practice model of stroke high-risk populations.Methods A total of 118 cases of stroke high-risk populations admitted to Guangdong 999 Brain Hospital from March to September 2020 were selected as the research objects, and they were divided into control group (59 cases) and observation group (59 cases) by random number method.The control group was treated with routine health management, and the observation group was treated with family-based health management.The scores of stroke prevention and control knowledge, health beliefs and health behaviors of the two groups were compared.Results There was no significant difference in the scores of stroke prevention and control knowledge, health beliefs and health behaviors between the two groups before intervention (P＞0.05);After 3 months of intervention, the scores of stroke prevention and control knowledge, health beliefs and health behaviors in the observation group were higher than those in the control group, and the differences were statistically significant (P＜0.05).Conclusion Familybased health management can improve the knowledge, attitude, belief and practice model of stroke high-risk populations, and provide a basis for formulating more effective primary stroke prevention health management programs.
		2021 Vol. 28 (20): 83-85转88 [Abstract] ( 34 ) HTML (33 KB) PDF (0 KB) ( 8 )

	86	Efficacy of invasive mechanical ventilation in the treatment of severe heart failure in ICU
		ZHANG Shu-juan PAN Xiao-bin SHI Song-chang LIN Xing-sheng
		Objective To investigate the effect of invasive mechanical ventilation in the treatment of ICU severe heart failure.Methods A total of 88 ICU patients with severe heart failure admitted to Fujian Provincial Hospital South Branch from September 2018 to September 2020 were selected as the research subjects.They were divided into control group (44 cases) and observation group (44 cases) according to the random number table method.The control group was treated with conventional treatment strategy, and the observation group was treated with invasive mechanical ventilation combined with conventional treatment strategy.The rates of clinical improvement, heart rate (HR), respiratory rate(RR), and total incidence of adverse reactions in the two groups were compared.Results The excellent and good rate of clinical condition improvement in the observation group was higher than that of the control group after 7 days of treatment, with statistical significance (P＜0.05).After 7 days of treatment, HR, RR and the total incidence of adverse reactions in the observation group were lower than those of the control group, with statistical significance (P＜0.05).Conclusion Invasive mechanical ventilation has better efficacy in the treatment of ICU severe heart failure, which can more effectively control the condition, improve the levels of HR and RR, and reduce the total incidence of adverse reactions,which is worthy of recommendation.
		2021 Vol. 28 (20): 86-88 [Abstract] ( 44 ) HTML (29 KB) PDF (0 KB) ( 5 )

	89	Effect of acupotomology relaxation combined with chiropractic on the degree of pain and disability in patients with scoliosis
		TANG Run-ke WU Lan-e XU Meng-bo JIANG Jue XIAO Di-hua
		Objective To explore the effect of acupotomology relaxation combined with chiropractic on the degree of pain and disability in patients with scoliosis.Methods The clinical data of 60 patients with scoliosis admitted to Jiangxi Integrated Traditional Chinese and Western Medicine Hospital from January 2019 to March 2020 were retrospectively analyzed.According to different treatment methods, the patients were divided into control group and experimental group, with 30 cases in each group.The control group received three small fixed-point chiropractic therapy, and the experimental group received acupotomology relaxation combined with chiropractic therapy.The correction effect of Cobb angle, pain degree and disability were compared between the two groups.Results 6 months after treatment, the Cobb angle of the two groups were smaller than before treatment, and the Cobb angle of the experimental group was smaller than that of the control group, and the correction rate of Cobb angle was higher than that of the control group,the differences were statistically significant (P＜0.05).At 3 and 6 months after treatment, visual analogue scale (VAS)scores in both groups were lower than before treatment, and VAS scores in the experimental group were lower than those in the control group, the differences were statistically significant (P＜0.05).At 3 and 6 months after treatment,Barthel index (BI) scores in both groups were higher than before treatment, and BI score in experimental group was higher than that in control group, the differences were statistically significant (P＜0.05).Conclusion Acupotomology relaxation combined with chiropractic can effectively reduce the pain degree of patients with scoliosis, promote the recovery of spinal morphology, and improve the ability of life.
		2021 Vol. 28 (20): 89-91 [Abstract] ( 39 ) HTML (33 KB) PDF (0 KB) ( 6 )

	92	Evaluation on the safety and efficacy of Tranexamic Acid used in the elderly patients during perioperative period of posterior cervical doubledoor laminoplasty
		ZHONG Yan-chun OUYANG Xun-yan YE Yong-jun LIU Wu-yang
		Objective To evaluate the safety and efficacy of Tranexamic Acid used in the elderly patients undergoing posterior cervical double-door laminoplasty during perioperative period.Methods A total of 66 elderly patients (age ≥60 years old) who underwent posterior cervical double-door laminoplasty in Department of Spine Surgery of the First Affiliated Hospital of Gannan Medical University from January 2018 to February 2020 were selected as the research subjects.The patients were divided into Tranexamic Acid group(35 cases)and control group(31 cases)according to Whether or not Tranexamic Acid was used during perioperative period.Control group received routine treatment, on the basis of the treatment of the control group,patients in the Tranexamic Acid group were given 1 g Tranexamic Acid before and after operation.The intraoperative blood loss, operating time, drainage amount in the first postoperative day, total drainage amount from the second day to extubation, hemoglobin on the third day after operation, perioperative hidden blood loss,total perioperative blood loss, the incidence of allogeneic blood transfusion and incidence of complications were compared between the two groups.Results The total perioperative blood loss, perioperative hidden blood loss and drainage amount in the first postoperative day of the Tranexamic Acid group were less than those in the control group, and the differences were statistically significant (P＜0.05).The concentration of hemoglobin after operation in the Tranexamic Acid group was higher than that in the control group, and the difference was statistically significant (P＜0.05).The incidence of allogeneic blood transfusions in Tranexamic Acid group(14.3%)was lower than that in the control group(38.7%),and the difference was statistically significant (P＜0.05).No significant differences were found in intraoperative blood loss, operating time, total drainage amount from the second day to extubation and the incidence of postoperative thrombosis-related complications between the two groups (P＞0.05).Conclusion Tranexamic Acid used in the elderly patients undergoing posterior cervical double-door laminoplasty can reduce postoperative blood loss, perioperative hidden blood loss and allogeneic blood transfusion, maintain hemoglobin level and without increasing the risk of thrombosis.
		2021 Vol. 28 (20): 92-95 [Abstract] ( 39 ) HTML (40 KB) PDF (0 KB) ( 8 )

	96	Clinical study of full digital design and 3D technology assisted lumbar intervertebral foramen endoscopic surgery
		FU Yu-liang SHENG Yu CHEN Rong ZHAO Long-dui YANG Qiu-na
		Objective To explore the effect of full digital design and 3D technology assisted lumbar intervertebral foramen endoscopic surgery.Methods Clinical data of 40 patients with lumbar disc herniation and lumbar spinal stenosis admitted to General Hospital of Pingxiang Mining Group Co., Ltd.from August 2018 to August 2019 were retrospectively analyzed.According to the operation method, they were divided into control group (20 cases) and observation group (20 cases).The control group was treated with conventional intervertebral foramen endoscopic surgery, while the observation group was treated with full digital design and 3D technology assisted lumbar intervertebral foramen endoscopic surgery.The clinical efficacy, operation and complications were compared between the two groups.Results There was no significant difference in the total effective rate between the two groups at 1, 3, 6 months and 1 year after operation (P＞0.05).The puncture time and operation time of the observation group were shorter than those of the control group, and the number of fluoroscopy and intraoperative blood loss were less than those of the control group, the differences were statistically significant (P＜0.05).Following up for 1 year, the total occurrence rate of the observation group was lower than that of the control group, and the difference was statistically significant (P＜0.05).Conclusion The full digital design and 3D technology assisted lumbar intervertebral foramen endoscopic surgery has a significant effect,which is conducive to the smooth operation and less postoperative complications, and is worthy of clinical promotion.
		2021 Vol. 28 (20): 96-98转105 [Abstract] ( 35 ) HTML (32 KB) PDF (0 KB) ( 8 )

	99	Application study of 3D printing technology in Pilon fracture surgery
		WEN Rui-can SHEN Zi-wei TAN Jian-ji
		Objective To investigate the application effect of 3D printing technology in Pilon fracture surgery.Methods A total of 60 patients with Pilon fracture treated in Luoding People′s Hospital from May 2018 to April 2020 were selected as the research objects, and they divided into control group (30 cases) and observation group (30 cases) according to the random number table method.The control group received open reduction and internal fixation according to the conventional method, and the observation group printed out the Pilon fracture physical model, designed and formulated the individualized operation plan before the operation.The fracture reduction, the operation time, postoperative complications and joint function score were compared between the two groups.Results The operation time of the observation group was shorter than that of the control group, the difference was statistically significant (P＜0.05).At the 3 d postoperative reexamination, the excellent and good rate of reduction in the observation group was higher than that in the control group, the difference was statistically significant (P＜0.05).The joint function score of the observation group at 3 months after operation was higher than that of the control group, the difference was statistically significant (P＜0.05).After 5 months of follow-up, the incidence of complications in the observation group was lower than that in the control group, the difference was statistically significant (P＜0.05).Conclusion 3D printing technology can effectively improve the fracture reduction of patients with Pilon fracture surgery, shorten the operation time, reduce complications,accelerate rehabilitation and improve the prognosis.It has high clinical application value and is worthy of promotion.
		2021 Vol. 28 (20): 99-101 [Abstract] ( 39 ) HTML (32 KB) PDF (0 KB) ( 8 )

	102	Comparison of the efficacy and safety of only posterior approach and posterior combined anterior approach surgery in the treatment of patiens with spinal tuberculosis
		PAN Rui-kang PAN Yan-qun
		Objective To compare the efficacy and safety of only posterior approach and posterior combined anterior approach surgery in the treatment of patiens with spinal tuberculosis.Methods A total of 70 patients with spinal tuberculosis admitted to the Fifth People′s Hospital of Ganzhou City from February 2019 to August 2020 were selected as the research subjects.According to random number table method, they were divided into control group (35 cases)and observation group (35 cases).The control group was treated with posterior operation alone, and the observation group was treated with combined anterior and posterior operation.The surgical parameters,Cobb angle changes and complications were compared between the two groups.Results The operation time and hospitalization time of the observation group were longer than those of the control group, and the amount of intraoperative blood loss was more than that of the control group, the differences were statistically significant (P＜0.05).There was no significant difference in the total incidence of complications between the two groups (P＞0.05).Cobb angle of the observation group was lower than that of the control group, the degree of correction and the correction rate of the observation group were higher than those of the control group, the differences were statistically significant (P＜0.05).Conclusion Posterior treatment alone has shorter operation time and hospital stay, and less intraoperative blood loss, while combined anterior and posterior treatment is more effective in removing lesions and correcting deformities.Both of them have their own advantages and high safety,and the appropriate surgical methods can be selected according to the patient′s situation.
		2021 Vol. 28 (20): 102-105 [Abstract] ( 41 ) HTML (32 KB) PDF (0 KB) ( 8 )

	106	Clinical effect of DCCIK immunotherapy combined with chemotherapy in the treatment of lung cancer
		WANG Ling1 QIU Zhi-min2 DAI Yue1▲
		Objective To investigate the long-term and short-term clinical effects of DCCIK immunotherapy combined with chemotherapy on patients with lung cancer.Methods The clinical data of 60 patients with lung cancer admitted to Jiangxi Cancer Hospital from January 2016 to June 2016 were retrospectively analyzed.According to different treatment methods, they were divided into group A and group B, with 30 patients in each group.Group A was treated with DCCIK combined with chemotherapy treatment methods, group B was treated with chemotherapy alone.The disease control rate, karnofsky (KPS) score, and long-term efficacy were compared between the two groups.Results After treatment,the total improvement rate of KPS in group A was higher than that in group B, and the difference was statistically significant (P＜0.05).The 1-year survival rate of group A was higher than that of group B, the 2-year survival rate of group A was higher than that of group B, the median survival time of group A was higher than that of group B, and the differences were statistically significant (P＜0.05).Conclusion DCCIK immunotherapy combined with chemotherapy is effective in the treatment of patients with lung cancer, which can significantly improve the quality of life of patients and increase the survival time of the disease.
		2021 Vol. 28 (20): 106-108 [Abstract] ( 41 ) HTML (31 KB) PDF (0 KB) ( 6 )

	109	Expression of T lymphocyte subsets in peripheral blood of patients with advanced lung cancer after targeted therapy and its clinical significance
		ZHOU Jin LUO Hong LIN Zheng CHEN Zhi-gang HUANG Kai-rong
		Objective To investigate the expression of lymphocyte subsets in peripheral blood T patients with advanced lung cancer after targeted therapy.Methods A total of 50 patients with targeted therapy for lung cancer who were hospitalized in the oncology department of Shangrao People′s Hospital from August 2016 to July 2018 were selected as the experimental group, and a total of 50 people who went to Shangrao People′s Hospital for health examination during the same period were selected as the control group.The venous blood of the two groups was selected as the control group,the T lymphocyte subsets in the samples were detected by flow cytometry, and the T lymphocyte subsets in the two groups were observed.The experimental group was treated, and the content changes of T lymphocyte subsets before and after treatment were observed.Results The CD4+、CD4+/CD8+ content of the experimental group lower than that of the control group, and the CD8 content was significantly higher than that of the control group, and the differences were statistically significant (P＜0.05).The CD4+、CD4+/CD8+ content after treatment was higher than that before treatment, and the CD8+content was lower than that before treatment, and the differences were statistically significant (P＜0.05).Conclusion Targeted therapy can effectively improve the immune status of patients with advanced lung cancer, and observing the changes of CD4+、CD4+/CD8+、CD8+content can be beneficial to the treatment of the patient was evaluated.
		2021 Vol. 28 (20): 109-111 [Abstract] ( 37 ) HTML (34 KB) PDF (0 KB) ( 8 )

	112	Clinical effect of neoadjuvant concurrent radiotherapy and chemotherapy in the treatment of locally advanced rectal cancer
		ZHANG Xiao-xiao
		Objective To investigate the clinical effect of neoadjuvant concurrent radiotherapy and chemotherapy in the treatment of locally advanced rectal cancer.Methods A total of 82 patients with locally advanced rectal cancer admitted to Anshan Cancer Hospital from January 2019 to January 2020 were selected as the research objects, and were divided into radiotherapy alone group (41 cases) and neoadjuvant concurrent radiotherapy and chemotherapy group according to the random number table method (41 cases).The radiotherapy alone group was treated with radiotherapy alone, neoadjuvant concurrent radiotherapy and chemotherapy group was treated with neoadjuvant concurrent radiotherapy and chemotherapy.The two groups disease control excellent and good rate and adverse reaction rate were compared.Results The rate of good condition control in the neoadjuvant concurrent radiotherapy group was higher than that of the radiotherapy group alone, and the difference was statistically significant (P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion The clinical effect of neoadjuvant concurrent radiotherapy and chemotherapy for locally advanced rectal cancer is more significant.
		2021 Vol. 28 (20): 112-114 [Abstract] ( 40 ) HTML (27 KB) PDF (0 KB) ( 7 )

	115	Evaluation of the clinical study of left ventricular diastolic dysfunction in the treatment of pregnancy-induced hypertension
		ZHANG Wei YUAN Zhen HUANG Mei-ling
		Objective To explore the clinical significance of left ventricular diastolic dysfunction in the treatment of pregnancy-induced hypertension (PIH).Methods Thirty patients with PIH who were treated with Magnesium Sulfate and Nifedipine at Yichun People′s Hospital from February 2018 to May 2020 were selected as research subjects.All patients received ultrasound blood vector flow mapping (VFM) before treatment and 7 days after treatment.The left ventricular diastolic function parameters and left ventricular energy loss (EL) parameters of the left ventricular diastolic phases of PIH before treatment and 7 days after treatment were analyzed.The correlation between EL and left ventricular diastolic function parameters were also analyzed.Results After 7 days of treatment, the late diastolic peak flow rate(A) of the mitral valve, the early mitral valve peak flow rate (E)/early diastolic myocardial velocity (e), isovolumic relaxation time (IRT), peak E deceleration time (EDT), Tei index, and e/late diastolic myocardial velocity (a) were lower than those before treatment.The E/A and e value were higher than those before treatment, and the differences were statistically significant (P＜0.05).There was no statistically significant difference in E value or a value before treatment and 7 days after treatment (P＞0.05).The EL parameters of each phase of the left ventricular diastole after 7 days of treatment were lower than those before treatment with statistical differences (P＜0.05).P4-EL in PIH patients was not correlated with EDT and P1-EL was not with IRT (P＞0.05).P3-EL was negatively correlated with E/A (P＜0.05), and positively correlated with a, e, and E/e (P＜0.05), but was not correlated with e/a (P＞0.05).P5-EL was positively correlated with e,a, A and e/a (P＜0.05), and negatively correlated with E/A (P＜0.05).Conclusion Quantitative evaluation of intracavitary blood flow EL in patients with PIH can evaluate the degree of left ventricular diastolic dysfunction and the effect of treatment.
		2021 Vol. 28 (20): 115-117转121 [Abstract] ( 35 ) HTML (35 KB) PDF (0 KB) ( 7 )

	118	Clinical effect of Dienogest in the treatment of recurrent ovarian endometriosis
		ZHU Yi-rong1 FANG Shu-fen1 PENG Shu-hua2
		Objective To explore the clinical efficacy of Dienogest in the treatment of recurrent ovarian endometriosis(OEM).Methods A total of 40 patients with recurrent OEM admitted to Jiangxi Maternity and Child Health Hospital from September 2019 to March 2020 were selected as the research objects and divided into the control group and the observation group by random number table method, with 20 cases in each group.Patients in the control group were treated with Drospirenone Ethinyl Estradiol Tablets, and in the observation group, patients were treated with Dienogest.The menstruation, endometriotic cyst volume, dysmenorrhea, chronic pelvic pain or dyspareunia visual analogue scale(VAS) score, serum carbohydrate antigen 125 (CA125), blood lipid levels and the incidence of adverse reactions were compared between the two groups before treatment and 3 and 6 months after treatment.Results There were no statistically significant differences in the rate of normal menstrual frequency and normal menstrual period between the two groups after treatment (P＞0.05).There were no statistically significant differences in volume of cysts, VAS score of dysmenorrhea, VAS score of pelvic pain or dyspareunia, serum CA125, triglyceride and total cholesterol between the two groups before treatment (P＞0.05).After 6 months of treatment, the volume of cysts in the observation group was lower than that in the control group, VAS score of dysmenorrhea, VAS score of pelvic pain or dyspareunia and serum CA125 in the observation group were lower than those in the control group, and the differences were statistically significant (P＜0.05).There were no statistically significant differences in triglyceride, total cholesterol and clinical adverse reactions between the two groups after six months of treatment (P＞0.05).Conclusion Dienogest can significantly relieve pain, reduce the volume of cysts and serum CA125 in OEM patients, and the clinical effect is good.
		2021 Vol. 28 (20): 118-121 [Abstract] ( 49 ) HTML (34 KB) PDF (0 KB) ( 7 )

	122	Effect comparison of Terbutaline combined with Beclomethasone Propionate/Budesonide in the treatment of acute attack of mild to moderate asthma in children
		HU Niu
		Objective To investigate the clinical effect of Beclomethasone Propionate and Budesonide with Terbutaline in treatment of mild to moderate childhood asthma exacerbations.Methods A total of 100 children with mild to moderate asthma acute attack admitted to People′s Hospital of Songzi City from January 2019 to April 2020 were selected as the research objects.According to the random number table method, they were divided into the control group and the observation group, with 50 cases in each group.The control group was given Budesonide combined with Terbutaline,and the observation group was given Beclomethasone Propionate combined with Terbutaline.After 7 days of treatment,the clinical efficacy, symptom disappearance time, hospital stay, symptom score, pulmonary function indexes and the incidence of adverse reactions were compared between the two groups.Results After 7 days of treatment, there was no statistically significant difference in the total effective rate between the two groups (P>0.05).There were no statistically significant differences in cough, dyspnea, pulmonary wheezing, disappearance time and hospitalization time between the two groups (P>0.05).There were no statistically significant differences in nocturnal and daytime symptom scores between the two groups (P>0.05).There were no statistically significant differences in 1 second forced expiratory volume(FEV1), FEV1/forced vital capacity (FVC) between the two groups (P>0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion The clinical effect of Beclomethasone Propionate and Budesonide with Terbutaline in treatment of mild to moderate childhood asthma exacerbations are similar, can effectively improve the clinical symptoms, signs and lung function of the children, and there is no increase in adverse reactions, it is worthy of promotion and application.
		2021 Vol. 28 (20): 122-125 [Abstract] ( 44 ) HTML (36 KB) PDF (0 KB) ( 7 )

	126	Clinical study of hysteroscopy in freeze thawed embryo transfer in patients with uterine diverticulum
		MEI Jin-feng YANG Li-juan MA Ling ZHANG Li-li FAN He-hua▲
		Objective To investigate the effect of hysteroscopy on the clinical outcome and safety of frozen thawed embryo transfer in patients with uterine diverticulum.Methods A total of 100 cases of cases of patients with infertility secondary to uterine diverticulum admitted to the Department of Reproductive Medicine of Nanchang Reproductive Hospital from January 2019 to January 2020 were selected as the research objects, and divided into control group and study group according to random number table method, with 50 cases in each group.The control group received frozen thawed embryo transfer, the study group received hysteroscopic electrosurgical excision surgery and frozen thawed embryo transfer.Clinical pregnancy outcome and safety index were compared between the two groups.Results The positive rate of serum human chorionic gonadotropin, clinical pregnancy rate and twin pregnancy rate in the study group were higher than those in the control group, the differences were statistically significant (P＜0.05).The early abortion rate in the study group was lower than that in the control group, and the difference was statistically significant (P＜0.05).There was no significant difference in the number of ectopic pregnancy and monozygotic twins between the two groups(P＞0.05).There was no significant difference in the incidence of endometrium in secretary phase, focal fibrosis, chronic endometritis and a small amount of lymphocyte infiltration between the two groups (P＞0.05).Conclusion Uterine diverticulum after cesarean section can reduce the clinical pregnancy rate of embryo transfer patients, but hysteroscopic electrotomy before freeze thawed embryo transfer can improve the clinical pregnancy outcome with high safety.
		2021 Vol. 28 (20): 126-129 [Abstract] ( 39 ) HTML (35 KB) PDF (0 KB) ( 6 )

	130	Clinical effect of laparoscopic suspension of high uterosacral ligament for uterine prolapse
		DING Cheng-yu LIANG Yan WANG Xiao-jiao ZHANG Hai-juan
		Objective To investigate the clinical effect of laparoscopic suspension of high uterosacral ligament for uterine prolapse.Methods A total of 88 patients with uterine prolapse admitted to the Department of Gynecology, the First People′s Hospital of Aksu Prefecture from October 2018 to July 2020 were selected as the research subjects and divided into control group (44 cases) and experimental group (44 cases) according to random drawing method.The control group used laparoscopic assisted vaginal hysterectomy and vaginal anterior and posterior wall repair, and the experimental group used laparoscopic high uterosacral ligament suspension.Clinical efficacy, surgical indexes, sexual function and quality of life were compared between the two groups.Results The total effective rate of experimental group was higher than that of control group, and the difference was statistically significant (P＜0.05).There was no significant difference in operation time, intraoperative blood loss and hospital stay between the two groups (P＞0.05).Postoperatively, the scores of pelvic organ prolapse and urinary incontinence sexual function scale (PISQ-12) and quality of life(QOL) of pelvic organ prolapse and urinary incontinence in experimental group were higher than those in control group,the differences were statistically significant (P＜0.05).Conclusion Laparoscopic suspension of high uterosacral ligaments is effective in the treatment of uterine prolapse, which can improve sexual function and quality of life
		2021 Vol. 28 (20): 130-132 [Abstract] ( 47 ) HTML (31 KB) PDF (0 KB) ( 6 )

	133	Clinical effect of lung ultrasonic-assisted vibrating sputum discharge in the treatment of neonatal pneumonia
		CHEN Jun LIU Kai-lian HUANG Chao-mei DAI Yi-heng▲
		Objective To investigate the clinical effect of lung ultrasound-assisted vibrating sputum drainage in the treatment of neonatal pneumonia.Methods A total of 70 cases of neonatal pneumonia admitted to Foshan Women and Children Hospital from January 2019 to January 2020 were selected as the research subjects, and divided into study group (35 cases) and control group (35 cases) according to random number table method.The study group was treated with lung ultrasonic localization assisted vibration sputum drainage, the control group was treated with conventional vibration sputum drainage.The treatment effect, blood gas analysis indexes, time to stop oxygen, time to disappear cough,length of hospital stay and incidence of complications were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P＜0.05).At 10, 30 min after treatment, the oxygen partial pressure in the study group was higher than that in the control group, the carbon dioxide content was lower than that in the control group, the differences were statistically significant(P＜0.05).The time needed to stop oxygen, the time to disappear cough and the length of hospital stay in the study group were all shorter than those in the control group, the differences were statistically significant (P＜0.05).No intracranial hemorrhage occurred in the two groups.Conclusion Lung ultrasound guided chest physiotherapy is safe and effective in the treatment of neonatal pneumonia.
		2021 Vol. 28 (20): 133-135 [Abstract] ( 41 ) HTML (33 KB) PDF (0 KB) ( 6 )

	136	Clinical outcome study of freeze-thaw embryo transfer with retarded embryo on fertilization day 3
		QIU Pei-chang CHEN Cai-rong▲ KUANG Yu-lan ZHAO Xiao-ying WANG Qiu-xiang LI Yan-hong CHEN Wan-le
		Objective To investigate the clinical outcome of retarded embryo for frozen-thawed embryo transfer (FET)cycle on fertilization day 3.Methods Retrospective analysis of the clinical data of 684 patients with the cycle FET admitted to Reproductive Center, Guangzhou Medical University Affiliated Sixth Hospital (Qingyuan People′s Hospital)from January 2015 to March 2020 was made, they were divided into group A (4-5 cell group) and group B (7-9 cell group) according to the different number of embryos blastocyst on day 3 of fertilization.Pregnancy outcomes were compared between the two groups.Results The clinical pregnancy rate and live birth rate of the group A were lower than those of the group B, the differences were statistically significant (P＜0.05).There were no statistically significant differences in biochemical pregnancy rate, ectopic pregnancy rate, abortion rate and multiple (twin) pregnancy rate as well as the mean birth weight between two groups (P＞0.05).Conclusion The clinical pregnancy rate of retarded embryo on fertilization day 3 can is lower than that of normal embryos, but the clinical outcome of pregnant patients after transplantation is similar to that of normal embryos.Retarded embryo can be frozen as a reserve to reduce the waste of resources and the mental and financial burden on patients.
		2021 Vol. 28 (20): 136-139 [Abstract] ( 37 ) HTML (35 KB) PDF (0 KB) ( 5 )

	140	Effect analysis of continuous oral health education on prevention of dental caries in preschool children
		FAN Ying-yan1 WEN Xiang2 CAO Xiao-jun1 WEI Xiao-qin1 DENG Wei1
		Objective To explore the effect of continuous oral health education on the prevention of dental caries in preschool children.Methods A total number of 120 children from 3 to 4 years old in 2 kindergartens and their parents from Donghu District, Nanchang City were selected.The selection period was from March 2017 to September 2018.Children and their parents in one kindergarten were classified as the intervention group (60 children), and children and their parents in the another kindergarten were classified as the control group (60 children).The control group were given traditional oral health education for 3 months, and the intervention group was given continuous oral health education and traditional oral health education for 3 months.The incidence of caries before and after intervention, number of caries per capita, oral health knowledge mastery, and compliance after intervention were compared between the two groups.Results Before intervention, the incidence of caries in 120 children was 50.00%, and the number of caries per capita was (2.75±0.07) teeth.The incidence of caries and number of caries per capita in the control group after intervention were higher than those before intervention, with statistically significant differences (P＜0.05).The incidence of caries and number of caries per capita in the intervention group after intervention were higher than those before intervention, without statistically significant differences (P＞0.05).In the control group, the number of children who mastered that correct tooth brushing could prevent caries, correct tooth brushing methods, and mouthwash after meals after intervention was greater than that before intervention, without statistically significant difference (P＞0.05).In the intervention group, the number of children who mastered that correct tooth brushing could prevent caries, correct tooth brushing methods, and mouthwash after meals after intervention was greater than that before intervention, with statistically significant difference (P＜0.05).According to children′s behaviors such as brushing their teeth in the morning and evening,not picky eaters, and regular visits to the dentist, the compliance after intervention of the intervention group was higher than that of the control group, with statistically significant difference (P＜0.05).Conclusion Continuous oral health education for preschool children can effectively prevent the incidence of caries.It can also significantly improve the children′s knowledge and compliance, and develop good oral hygiene behaviors.
		2021 Vol. 28 (20): 140-143 [Abstract] ( 36 ) HTML (35 KB) PDF (0 KB) ( 7 )

	144	Effect of local administration of Dexamethasone in thyroid surgery on functional recovery of recurrent laryngeal nerve
		DENG Hui-dian HUANG Jin-long WANG Juan
		Objective To investigate the effect of local administration of Dexamethasone in thyroid surgery on the functional recovery of recurrent laryngeal nerve (RLN).Methods Sixty patients with thyroid occupying disease who were admitted to Jingdezhen Third People′s Hospital from August 2019 to September 2020 were selected and divided into the high dose group, the low dose group and the control group by the random number table method, with 20 cases in each group.During the surgery, the control group was given local wet compress of 5 mL normal saline;the high dose group was given local wet compress of 5 mg dexamethasone + 5 mL normal saline;the low dose group was given local wet compress of 3 mg Dexamethasone+ 5 mL normal saline.The recovery of vocal cord motion and sound quality of the three groups were compared after surgery.Results No significant differences were observed in the recovery rates of vocal cord motion among the three groups at 1 month after surgery (P＞0.05).The respective recovery rate of vocal cord motion in the high dose group and low dose group was higher than that in the control group at 3 months after surgery,and the differences were statistically significant (P＜0.05).The respective recovery rate of vocal cord motion in the high dose group and the low dose group at 3 months after surgery was higher than that at 1 month after surgery, with statistically significant differences (P＜0.05).In the control group,the recovery rate of vocal cord motion at 3 months after surgery was higher than that at 1 month after surgery, but the difference was not statistically significant (P＞0.05).No significant difference was observed in the recovery rate of vocal cord motion at 3 months after surgery between the high dose group and the low dose group (P＞0.05).The respective improvement rate of sound quality in the high dose group and the low dose group was higher than that in the control group at 3 months after surgery,with statistically significant differences (P＜0.05).No significant difference was observed in the total improvement rate of sound quality between the high dose group and the low dose group at 3 months after surgery (P＞0.05).Conclusion Intraoperative local administration of Dexamethasone in patients undergoing thyroid surgery can promote the recovery of RLN function and improve the sound quality.
		2021 Vol. 28 (20): 144-146转150 [Abstract] ( 50 ) HTML (34 KB) PDF (0 KB) ( 7 )

	147	Observation on the effect of special orthodontic retainer in orthodontics and its influence on the quality of life of patients
		LUO Ying1 ZHOU Li2 CHEN Ya-duo1▲
		Objective To explore and analyze the effect of special orthodontic retainers in orthodontics and its impact on the quality of life of patients.Methods A total of 60 orthodontic patients admitted to West China Hospital of Stomatology, Sichuan University from January 2018 to January 2020 were selected as the research objects.They were divided into observation group (30 cases) and control group (30cases) according to the order of admission time.The control group used the Hawley retainey method, and the observation group used the improved hot-pressed film transparent crown retainer method.The width of the canine arch and the width of molar arch, living mass, diet, sleep quality, and self-conscious symptoms were compared between the two groups.Results After follow-up, the patients of two groups showed no significant differences in the width of the upper and lower canine arch and molar archwidth (P＞0.05);the molar arch width and Little index of the observation group were lower than those of the control group, the difference was statistically significant (P＜0.05);after treatment, the observation group′s quality of life, quality of sleep, and selfconscious symptoms scores were higher than those of the control group, and the differences were statistically significant(P＜0.05).The satisfaction scores with masticatory function, comfort, aesthetics, and language pronunciation of the observation group was higher than that of the control group, and the differences were statistically significant (P＜0.05).Conclusion The improved heat-pressing film transparent crown retainer has a definite effect in orthodontics and is worthy of optimization.
		2021 Vol. 28 (20): 147-150 [Abstract] ( 47 ) HTML (33 KB) PDF (0 KB) ( 7 )

	151	Effect of small incision non-phacoemulsification extracapsular extraction in the treatment of senile cataract and its influence on vision
		DU Wei-feng HAN Ying-jun CHEN Jian-li SUN Dan
		Objective To observe the effect of small incision non-phacoemulsification extracapsular excision in the treatment of senile cataract and its influence on vision.Methods A total of 76 elderly cataract patients who were admitted to the Department of Ophthalmology of Renhe Hospital of Beijing from February 2018 to April 2020 were selected as the research objects, and they were divided into a conventional group (38 cases) and a study group (38 cases) according to the random number table method.Patients in the conventional group used phacoemulsification and extracapsular phacoemulsification patients in the study group used small incision non-phacoemulsification extracapsular extraction.The intraocular pressure, visual acuity and adverse reactions of patients of the two groups were compared.Results The comparison of the intraocular pressure before treatment between the two groups was not statistically significant (P＞0.05);the intraocular pressure after treatment in the conventional group was higher than that before treatment, and the difference was statistically significant (P＜0.05);the intraocular pressure after treatment in the study group was higher than that before treatment, the difference was statistically significant (P＜0.05);the intraocular pressure of the study group at 2, 6, 12 and 24h after treatment was lower than that of the conventional group, and the difference was statistically significant (P＜0.05).The visual acuity comparison between the two groups before treatment and 3 months after treatment was not statistically significant (P＞0.05);the visual acuity after treatment in the conventional group was higher than that before treatment, and the difference was statistically significant (P＜0.05);The visual acuity after treatment in the study group was higher than that before treatment, and the difference was statistically significant (P＜0.05);the visual acuity of the study group was higher than that of the conventional group at 1 week after treatment, and the difference was statistically significant (P＜0.05).The total incidence of adverse reactions in the study group was lower than that in the routine group, and the difference was statistically significant (P＜0.05).Conclusion In the choice of treatment for elderly cataract patients, small-incision non-phacoemulsification extracapsular extirpation can be taken into consideration, which is safe and effective and worthy of application.
		2021 Vol. 28 (20): 151-153转163 [Abstract] ( 37 ) HTML (33 KB) PDF (0 KB) ( 7 )

	154	Study on the coincidence rate of fetal weight prediction by ultrasound fetal measurement system
		LIU Liang-gang1 LIN Li-hui2 TANG Yu-lan1
		Objective To explore the application of fetal growth parameters measured by ultrasound in fetal weight prediction.Methods A total of 500 healthy pregnant women whose fetal weight was estimated by ultrasonic measurement system within 72 hours of full-term delivery from January 2017 to December 2019 in Dongguan Guangji Hospital and Dongguan Jinmeiji Women′s and Children′s Hospital were retrospectively selected as research objects.The biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC) and femur length (FL) of the fetus were measured by ultrasound from 36 weeks to 41 weeks of pregnancy, and compared with the actual weight of the baby within 72 hours of birth.The equation for predicting fetal weight was obtained by unit and multiple linear regression analysis.Results Combining the indexes of BPD, HC, AC and FL, the correlation between the predicted fetal weight and the actual birth weight was the highest (r=0.933).The coincidence rate between the predicted fetal weight and the actual birth weight was 83.2%.Conclusion The application of ultrasonic measurement system to predict fetal weight is simple and accurate, which can improve the one-sidedness of other methods in fetal measurement, the objectivity and accuracy of the overall measurement index and better serve the clinic.
		2021 Vol. 28 (20): 154-156 [Abstract] ( 33 ) HTML (30 KB) PDF (0 KB) ( 6 )

	157	Study on evaluation of digital breast tomosynthesis (DBT) replacing fullfield digital mammography
		LIU Lei DENG Shu-zhen DING Ai-min HU Ming
		Objective To evaluate the feasibility of digital breast tomosynthesis (DBT) replacing full-field digital mammography (FFDM).Methods The clinical data of 120 cases of patients suspected with breast disease who were admitted to the No.1 People′s Hospital of Fuzhou from June 2018 to July 2020 due to personal physical examination, breast pain,breast discomfort, self-reported touch with mass were retrospectively selected and compared.According to the examination methods, the patients were divided into the DBT group (n=60) and the FFDM group (n=60).With the postoperative pathological examination results as the gold standard, the diagnostic value of DBT and FFDM for breast lesions was analyzed, and the diagnostic value of DBT and FFDM for breast lesions was statistically analyzed.Results The diagnostic sensitivity of DBT in breast lesions was higher than that of FFDM, with statistical differences (P＜0.05);but there were no significant differences in the specificity, diagnostic accuracy, positive predictive value and negative predictive value between DBT and FFDM (P＞0.05).Conclusion DBT is feasible to replace FFDM, with high diagnostic sensitivity,it is worthy of promotion and application in the clinical.
		2021 Vol. 28 (20): 157-159 [Abstract] ( 51 ) HTML (30 KB) PDF (0 KB) ( 7 )

	160	Comparison of clinical value of multisice computed tomography and digital radiography in the diagnosis of peripheral lung cancer
		LIU Bing
		Objective To investigate the clinical value of multisice computed tomography (MSCT) and digital radiography(DR)in the diagnosis of peripheral lung cancer.Methods A total of 75 patients with peripheral lung cancer admitted to the First People′s Hospital of Shenyang from October 2017 to October 2019 were selected as the research objects,and multi-slice spiral CT and DR examination were performed respectively.The clinical diagnostic rate and TNM staging coincidence rate of the two methods were compared.Results The detection rates of lobulation sign, cavity sign, burr sign, vacuole sign and bronchus sign, pleural effusion, spinous process, mediastinal lymph node enlargement and pleural indentation sign in 64 slice MSCT were higher than those in DR, with statistical differences (P＜0.05).The clinical diagnostic rate of 64 slice MSCT in the diagnosis of peripheral lung cancer(90.6667%)was higher than that of DR(70.6667%),the difference was statistically significant (P＜0.05).The diagnostic coincidence rate of 64 slice MSCT (90.6667%) was higher than that of DR (65.3333%), the difference was statistically significant (P＜0.05).Conclusion The 64-slice MSCT can clearly show the signs of patients with peripheral lung cancer.The detection rate of peripheral lung cancer is relatively high, and the diagnostic coincidence rate for clinical TNM staging is relatively high, which is of great value for the diagnosis of peripheral lung cancer.
		2021 Vol. 28 (20): 160-163 [Abstract] ( 38 ) HTML (31 KB) PDF (0 KB) ( 8 )

	164	Analysis of ultrasound image and blood flow characteristics of ovarian tumors in menopausal women
		ZHANG Yue
		Objective To investigate the characteristics of color Doppler sonography and hemodynamics of ovarian tumors in menopausal women.Methods The clinical data of 100 menopausal ovarian tumor patients admitted to the Department of Ultrasound of Jinzhou Central Hospital from July 2017 to October 2019 were retrospectively analyzed.The final pathological diagnosis result was taken as the gold standard, including 68 cases of benign tumors (benign group)and 32 cases of malignant tumors (malignant group), and the characteristics of color Doppler ultrasonography and hemodynamic indexes of the two groups were analyzed and compared.Results The proportion of unilateral incidence in the benign group was higher than that in the malignant group, the proportion of morphological rules was higher than that in the malignant group, the proportion of normal wall structure was higher than that in the malignant group, and the proportion of ascites was lower than that in the malignant group, the differences were statistically significant (P＜0.05).There was statistically significant difference in the maximum diameter of the unilateral ovary between the two groups(P＜0.05).The end diastolic velocity (Ved), peak systolic velocity (Vps), and mean velocity (VM) of the malignant group were higher than those of the benign group, and the differences were statistically significant (P＜0.05).The pulsatility index index (PI) and resistance index (RI) of the malignant group were lower than those of the benign group, the differences were statistically significant (P ＜0.05).Conclusion The characteristics of color Doppler ultrasonography and hemodynamics of benign and malignant ovarian tumors in menopausal women are obviously different, which can be used as the basis for clinical diagnosis and suitable for promotion.
		2021 Vol. 28 (20): 164-166 [Abstract] ( 42 ) HTML (31 KB) PDF (0 KB) ( 6 )

	167	Clinical effect of periocular acupuncture inducing resuscitation and unblocking meridians rehabilitation technology in the treatment of foot drop after stroke
		WANG Chao-fan ZHANG Wei▲
		Objective To investigate the clinical effect of periocular acupuncture inducing resuscitation and unblocking meridians rehabilitation technology in the treatment of foot drop after stroke.Methods A total of 60 patients with foot droop after stroke admitted to the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from April to October 2020 were selected as the research objects and divided into control group (30 cases) and treatment group(30 cases) according to random number table method.The control group was treated with conventional acupuncture on the basis of western medicine, and the treatment group was treated with periocular acupuncture inducing resuscitation and unblocking meridians rehabilitation technology on the basis of the control group.The therapeutic effect, functional walking ability grade (FAC) and freehand muscle strength rating scale (MMT) scores were compared between the two groups.Results The total effective rate of treatment group was higher than that of control group, the difference was statistically significant (P＜0.05).After treatment, the FAC grade of the two groups were better than before treatment, and the MMT score of the two groups was higher than before treatment, and the MMT score of the treatment group was higher than that of the control group, the differences were statistically significant (P＜0.05).However, after treatment, there was no significant difference in FAC grade between the two groups (P＞0.05).Conclusion The periocular acupuncture inducing resuscitation and unblocking meridians rehabilitation technology can improve the active range of ankle joint and the muscle strength of tibial anterior muscle in patients with foot drop after stroke, and the therapeutic effect is remarkable, which is worthy of popularization and application.
		2021 Vol. 28 (20): 167-170 [Abstract] ( 33 ) HTML (40 KB) PDF (0 KB) ( 6 )

	171	Clinical study on Yishen Tongluo method combined with acupuncture in the treatment of shoulder hand syndrome after stroke
		WU Gang YU Hong-mei LE Zhi-qing
		Objective To explore the clinical efficacy of Yishen Tongluo method combined with acupuncture in the treatment of shoulder hand syndrome (SHS)after stroke.Methods A total of 60 post-stroke SHS patients who were admitted to the Department of Stroke Diseases of Jingdezhen Hospital of Traditional Chinese Medicine in Jiangxi Province from October 2018 to June 2020 were selected as the research subjects, and they were divided into the control group(30 cases) and the treatment group (30 cases) according to the random number table method.The control group received only acupuncture treatment, the treatment group was given Yishen Tongluo tmethod on the basis of the control group.The visual analog scale (VAS) was used to evaluate the pain of the two groups before treatment and 10 days after treatment.The upper limb function assessment scale (DASH) was used to assess the ability of the upper limbs to engage in daily life in the two groups, and the degree of hand swelling in the two groups was measured with a centimeter soft ruler, and the clinical effects were compared between the two groups.Results There was no significant difference in the scores of DASH, swelling and VAS between the two groups before nursing (P＞0.05).At 10 days of treatment, the scores of DASH, swelling and VAS in the treatment group were lower than those in the control group, and the differences were statistically significant(P＜0.05).The total effective rate of treatment in the treatment group was higher than that in the control group, and the difference was statistically significant (P＜0.05).Conclusion For patients with post-stroke SHS, the treatment effect of Yishen Tongluo method combined with acupuncture is better, which can improve the ability of daily life of the affected limb, improve the symptoms of swelling and shoulder pain, and has high clinical application value.
		2021 Vol. 28 (20): 171-173 [Abstract] ( 35 ) HTML (31 KB) PDF (0 KB) ( 6 )

	174	Therapeutic effect observation of Herba Lysimachiae and Lygodium Japonicum hot package combined with auricular point embedding beans in stone expelling of patients with Shilin
		XIONG Ming-jie YANG Xu-fang ZHOU Mei-na
		Objective To investigate the therapeutic effect of Herba Lysimachiae and Lygodium Japonicum hot package combined with auricular point embedding beans in stone expelling of patients with Shilin.Methods From January 2018 to January 2019, 40 patients with urinary calculi in the Department of Nephrology and Urology of Jiujiang Hospital of Traditional Chinese Medicine were selected, and they were divided into the control group and the observation group according to random number table method, 20 cases in each group.The control group was treated with Paishi Granule,while the observation group was treated by oral administration of traditional Chinese medicine combined with hot package and auricular point embedding beans.The stone removal effect, stone discharge time, pain degree and safety were compared between the two groups.Results The total effective rate of the observation group was 100.00% (20/20), which was higher than 70.00% (14/20)of the control group,the difference was statistically significant (P＜0.05).The stone discharge time of the observation group was (3.86±0.84) d, which was shorter than that of the control group ([5.72±1.32]d),the difference was statistically significant (P＜0.05).The pain score after treatment of the observation group was (1.01±0.35)points,which was lower than that of the control group ([2.22±0.69]points), the difference was statistically significant(P＜0.05).There was no obvious adverse reaction in the two groups, and there were no abnormality in blood routine examination and liver and kidney function examination.Conclusion The therapeutic effect of Herba Lysimachiae and Lygodium Japonicum hot package combined with auricular point embedding beans is better for patients with Shilin, which is conducive to improve the treatment effect, shorten the stone discharge time, reduce the pain degree of patients, and has high safety, which is worthy of promotion and application.
		2021 Vol. 28 (20): 174-176转186 [Abstract] ( 40 ) HTML (33 KB) PDF (0 KB) ( 7 )

	177	Clinical effect of Sijunzi Decoction addition and subtraction in the treatment of chronic gastritis
		LI Ning
		Objective To investigate the clinical effect of Sijunzi Decoction addition and subtraction in the treatment of chronic gastritis.Methods A total of 40 patients with chronic gastritis in the Department of Traditional Chinese Medicine of the Second Hospital of Shunyi District from November 2018 to November 2019 were selected as the research objects, and they were divided into the study group (20 cases) and the control group (20 cases) according to random number table method.The control group was treated with conventional treatment, and the study group was treated with Sijunzi Decoction addition and subtraction on the basis of the control group.The total effective rate, the total incidence of adverse reactions and the recurrence rate of the two groups were compared.Results The total effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P＜0.05).The total incidence of adverse reactions in the study group was less than that in the control group, and the difference was statistically significant (P＜0.05).The recurrence rate in the study group was lower than that in the control group, and the difference was statistically significant (P＜0.05).Conclusion On the basis of conventional treatment, Sijunzi Decoction addition and subtraction can be used to treat chronic gastritis patients with better curative effect, and the incidence of adverse reactions is low and the recurrence rate is low.It is suitable for promotion and application in clinical.
		2021 Vol. 28 (20): 177-179 [Abstract] ( 36 ) HTML (29 KB) PDF (0 KB) ( 6 )

	180	Clinical effect of Compound Yinhua Jiedu Granules in the treatment of common cold
		ZHU Guang-xi
		Objective To discuss the clinical effect of Compound Yinhua Jiedu Granules in the treatment of common cold.Methods A total of 96 common cold patients treated in Anhui No.2 Provincial People′s Hospital from January to December 2019 were selected as the research objects.According to the random number table method, they were divided into the observation group (48 cases) and the control group (48 cases).The observation group was treated with Compound Yinhua Jiedu Granules, the control group was treated with Antiviral Granule.The clinical treatment effect, temperature change and symptom score between the two groups were compared.Results The total effective rate of the observation group was 89.58%, which was higher than 70.83% of the control group, the difference was statistically significant (P＜0.05).There was no significant difference of body temperature between the two groups before treatment (P＞0.05).After 4 h, 2 and 3 d of treatment, the body temperature in both groups were lower than those before treatment, the differences were statistically significcant (P＜0.05).Before treatment, there were no significant difference in the scores of symptoms such as headache, nasal congestion, runny nose, sore throat and cough between the two groups (P＞0.05).The symptom scores such as headache, nasal congestion, runny nose, sore throat and cough of the two groups after treatment were lower than those before treatment, the differences were statistically significant (P＜0.05).There were no significant difference in the symptom scores of headache, nasal congestion, runny nose, sore throat and cough in the two groups after treatment (P＞0.05).Conclusion In the treatment of common cold, the effect of compound Yinhua Jiedu Granules is good.Both compound Yinhua Jiedu Granules and Antiviral Granules can effectively improve symptoms.
		2021 Vol. 28 (20): 180-182 [Abstract] ( 45 ) HTML (32 KB) PDF (0 KB) ( 7 )

	183	Application comparison of immune and chemical fecal occult blood tests in early screening of colorectal cancer
		CAI Jin-ping1 LIU Qiong2 LI Qin2
		Objective To compare the effect of immune and chemical fecal occult blood tests (OBT) in the early screening of colorectal cancer.Methods A total of 50 suspected early colorectal cancer patients in Nanchang Hongdu Hospital of Traditional Chinese Medicine from May 2018 to January 2020 were selected as the research objects.The feces of the 50 patients were collected, and immune and chemical OBT tests were performed.The pathological results of biopsy were used as the "gold standard" for diagnosis.The diagnostic efficacy of immune and chemical OBT for early screening of colorectal cancer was compared.The immunofecal occult blood test (iFOBT) values of colorectal cancer patients with different prognosis were compared, and the receiver operating characteristic (ROC) curves were drawn to analyze the iFOBT values to predict the prognosis of colorectal cancer patients.Results Among the 50 suspected cases of early colorectal cancer, there were 30 cases (60.00%) of early colorectal cancer, 12 cases (24.00%) of colonic polyp and 8 cases (16.00%) of inflammatory bowel disease were confirmed by biopsy and pathological examination.The sensitivity,specificity, accuracy, positive predictive value and negative predictive value (96.67%, 90.00%, 94.00%, 93.55%,94.74%) of immune OBT in the diagnosis of colorectal cancer were higher than those of chemical OBT (70.00%,55.00%, 64.00%, 70.00%, 52.38%), and the differences were statistically significant (P＜0.05).The IFOBT value of patients with poor prognosis was higher than that of patients with good prognosis, and the difference was statistically significant (P＜0.05).The area under the ROC curve (AUC) of the iFOBT value was＞0.7 in diagnosis of colorectal cancer.The iFOBT value had a high value in predicting the prognosis of colorectal cancer, and the best predictive value could be reached when the optimal threshold was reached.Conclusion Compared with chemical OBT, immune OBT has higher clinical value and better screening effect in the early screening of colorectal cancer, and the prognosis of colorectal cancer can be predicted by the iFOBT value.
		2021 Vol. 28 (20): 183-186 [Abstract] ( 44 ) HTML (35 KB) PDF (0 KB) ( 7 )

	187	Application value of thyroid stimulating hormone receptor antibody in the diagnosis of Graves disease
		XIE Xiao-ting LIANG Jian-fu MO Chao-yun
		Objective To investigate the application value of thyroid stimulating hormone receptor antibody (TRAb) in the diagnosis of Graves disease.Methods A total of 760 cases of patients with thyroid diseases in People′s Hospital of Yangdong District in Yangjiang City from October 2019 to October 2020 were selected retrospectively.According to the clinical symptoms and signs, medical history and auxiliary examination results, they were divided into four groups:newly diagnosed Graves disease group (n=300), primary hypothyroidism group (n=200), thyroid nodule group (n=150)and hyperthyroidism subacute thyroiditis group (n=110).In addition, 50 cases of healthy people in the same period were selected as healthy control group.The serum levels of TRAb, anti-thyroid peroxidase antibody (ATpo), thyroglobulin antibody (TGAb) and the positive situations of the newly diagnosed Graves disease group and the healthy control group were statistically analyzed.The serum levels of TRAb and the positive situation of the five groups were statistically analyzed.The ROC curve was used to evaluate the application value of TRAb in the diagnosis of Graves disease.Results The serum levels of TRAb, ATpo and TGAb and their positive rates in the newly diagnosed Graves disease group were higher than those in the healthy control group, the differences were statistically significant (P＜0.05).The serum TRAb level of the newly diagnosed Graves disease group was higher than that of the primary hypothyroidism group, thyroid nodule group and hyperthyroidism subacute thyroiditis group, the differences were statistically significant (P＜0.05).The TRAb positive rate of the newly diagnosed Graves disease group was higher than that of the primary hypothyroidism group, thyroid nodule group and hyperthyroidism subacute thyroiditis group, the differences were statistically significant(P＜0.05).The area under the ROC curve of TRAb was 0.973, the critical v alue of diagnosis was 22.5 IU/mL,the sensitivity and specificity were 96.0% and 91.1% respectively, the correct rate, positive predictive value and negative predictive value were 92.6%, 82.8% and 98.1% respectively.Conclusion The application value of TRAb is high in the diagnosis of Graves disease.
		2021 Vol. 28 (20): 187-189转193 [Abstract] ( 42 ) HTML (33 KB) PDF (0 KB) ( 8 )

	190	Expression and significance of interleukin-1β, matrix metalloproteinase-7 and recombinant syndecan-1 in endometriosis
		XU Yong-hai YANG Qing-xun
		Objective To explore the expression and significance of interleukin-1β (IL-1β), matrix metalloproteinase-7(MMP-7) and recombinant syndecan-1 (SDC-1) in endometriosis.Methods A total of 100 patients with active endometriosis who were hospitalized in Bao′an Central Hospital of Shenzhen City from January 2019 to December 2020 were randomly selected as the research objects.According to the revised American Fertility Society, the study subjects were divided into mild group and moderate to severe group, 50 cases in each group, and 50 healthy women were selected as the control group during the same period.The enzyme-linked immunosorbent assay (ELISA) method was used to detect and compare the levels of serum IL-1β, MMP-7 and SDC-1 in each group, and the relationship between the expression of IL-1β, MMP-7 and SDC-1 and r-AFS score was analyzed.Results The expression levels of IL-1β,MMP-7 and SDC-1 in the moderate to severe group were higher than those in the mild group and the control group,and the differences were statistically significant (P＜0.05).The expression levels of IL-1β, MMP-7 and SDC-1 in the mild group were higher than those in the control group, and the differences were statistically significant (P＜0.05).Correlation analysis showed that the expressions of IL-1β, MMP-7 and SDC-1 were significantly positively correlated with endometriosis activity (r=0.78, 0.85, 0.82, P＜0.05).Conclusion IL-1β, MMP-7 and SDC-1 are highly expressed in endometriosis, and the three may cooperate with each other to promote the occurrence and development of endometriosis lesions.
		2021 Vol. 28 (20): 190-193 [Abstract] ( 44 ) HTML (33 KB) PDF (0 KB) ( 7 )

	194	Application value of fluorescence PCR melting curve analysis in detecting tuberculosis drug resistance
		WANG Yue1 MENG Pai-zhe2 YU Yan-hong1▲
		Objective To investigate the detection efficiency of Rifampicin and Isoniazid related drug resistance genes in sputum samples by fluorescence PCR melting curve analysis.Methods The sputum test results of 254 cases in the 10th People′s Hospital of Shenyang City from July 2019 to July 2020 were retrospectively analyzed.Using BACTEC MGIT 960 liquid drug sensitivity (hereinafter referred to as MGIT 960 drug sensitivity) as the reference standard, the effectiveness of the fusion curve method in the detection of Rifampicin and Isoniazid resistance were evaluated.Results Compared with MGIT 960, the sensitivity, specificity and Kappa values of Rifampicin resistance were 89.6%, 95.6%and 0.83.The sensitivity, specificity and Kappa values of Isoniazid resistance were 81.5%, 98.9% and 0.85.In the initial treatment of patients with good consistency, better than the retreatment of patients.Conclusion The method to detect patients with sputum samples of Rifampicin and Isoniazid resistance genes, compared with MGIT 960 DST method has good sensitivity and consistency, specific degree, can quickly detect patients with drug resistance situation and multidrug-resistant tuberculosis (MDR-TB) patients, especially for clinical patients to treat patients with early reference provides a quick and effective chemotherapy scheme.
		2021 Vol. 28 (20): 194-197 [Abstract] ( 32 ) HTML (33 KB) PDF (0 KB) ( 8 )

	198	Correlation analysis of rumination and social support in college students
		HE Ting-ting1 CHEN Si-yi1 ZHAO Liu-hong2 TANG Lu2 GUAN Ling2 PENG Li-xia1 CONG Li2▲
		Objective To investigate rumination and social support in college students, and analyze the correlation.Methods From March to May in 2019, a total of 410 students were selected from universities as the research objects according to the drawing lots.The general information, rumination response and perceived social support scale were used for investigation.Results Total score of rumination was (47.67±12.14) points, the lowest and highest were introspection and symptom rumination, respectively.Social support was (63.69±11.98) points and showed negative correlation with rumination (P＜0.05), which was most closely related to symptom rumination (P＜0.05), family support was the lowest.Boys and students with score under 60 had the lowest social support (P＜0.05).Conclusion Improving social support of college students, especially boys and poor academic performance, is helpful to promote active rumination and improve mental health.
		2021 Vol. 28 (20): 198-200转204 [Abstract] ( 44 ) HTML (35 KB) PDF (0 KB) ( 8 )

	201	Investigation and analysis on the individual dose level and health status of hospital radiation workers in Guangdong Province in 2019
		XIONG Liu-shan GUO Wei-zhen LIU Gui-xi HU Bi-hua
		Objective To analyze the overall situation of radiological protection training, dose detection and occupational health examination for hospital radiological workers in Guangdong Province in 2019.Methods A total of 646 radiological workers from three Grade A hospitals in Guangdong Province from January to December 2019 were selected as the research objects.The radiant dose level and health physical examination results of the subjects were stcounted,and the abnormal health physical examination of the hospital radiation staff with different professional categories and different length of service were compared.Results Annual radiant dose level of ＞1.0 mSv was 9.6% (62/646), annual radiant dose level of 0.5-1.0 mSv was 37.2% (240/646), annual radiant dose level of ＜0.5 mSv was 53.3% (344/646).A total of 646 hospital radiation staff receiving healthy physical examination, the highest rate of abnormalities was the eyes (24.5%[158/646]).The abnormal health physical examination of hospital radiation staff of different professional categories was compared, with no statistical significance (P＞0.05).With the length of service, the incidence of ophthalmology, electrocardiogram and abnormal blood pressure also increased, the differences were statistically significant (P＜0.05).Conclusion The average doses of radiation workers included in this study in 2019 are all within the range required by the corresponding standards.The highest rate of abnormalities detected in the 2019 Health Check is for the eyes.
		2021 Vol. 28 (20): 201-204 [Abstract] ( 34 ) HTML (34 KB) PDF (0 KB) ( 7 )

	205	Study on the correlation between the curriculum ideological cognition and the professional identity of nursing undergraduates
		YANG Duo-duo WEN Ke CHEN Mu-xi LIN Xiao-ling WANG Xiao-dan WAN Li-hong▲
		Objective To explore the correlation between the curriculum ideological cognition and professional identify of nursing undergraduates.Methods A cluster sampling method was conducted to select 50 sophomore nursing undergraduates of a university in Guangzhou.The nursing curriculum ideological cognition and professional identity were measured by curriculum ideological cognition questionnaire and nursing professional identity questionnaire in December 2019.Results The total scores of curriculum ideological cognition and professional identity of the students were (3.03±0.48) and (3.50±0.55) points.The result showed 86.0% participants claimed curriculum ideological education was necessary, and 84.0%-86.0% of them reported the quantity of curriculum ideological education was appropriate.Moreover,the satisfaction rate of curriculum ideological education was 98.0%.Curriculum ideological cognition was positively correlated with professional identity (r=0.767, P＜0.001).The results of single factor analysis showed that there were statistically significant differences in the professional identification scores under different gender, professional volunteer decision makers, awareness of curriculum ideological and political necessity, curriculum ideological and political experience, and ideological and political satisfaction (P＜0.05).The results of multi-factor analysis showed that participants who volunteered to major in nursing and had better curriculum ideological cognition got higher professional identity scores (P＜0.05).Conclusion Nursing undergraduates′ curriculum ideological cognition is better, whereas their professional identity need to be improved.Enhancing the awareness of the necessity of curriculum ideological cognition, carrying out curriculum ideological education appropriately and improving students′ satisfaction is beneficial to enhance nursing undergraduates′ professional identity.Nursing educators should pay more attention to students who major in nursing involuntarily to improve their professional identity in the future.
		2021 Vol. 28 (20): 205-208 [Abstract] ( 46 ) HTML (40 KB) PDF (0 KB) ( 7 )

	209	Analysis of oral hypoglycemic drugs used in Outpatient Department of Xianning Central Hospital from 2017 to 2019
		MAO Kang1 HU Ning2 ZENG Jin3▲
		Objective To analyze the current situation of oral hypoglycemic drugs in Xianning Central Hospital from 2017 to 2019, so as to promote rational drug use.Methods The data of oral hypoglycemic drugs used in the Outpatient Department of Xianning Central Hospital from 2017 to 2019 were analyzed by retrospective method, including amount of medication, defined daily dose (DDD), defined daily dose system (DDDs), defined daily cost (DDC) and ranking ratio(B/A).Results From 2017 to 2019, the consumption sum of various oral hypoglycemic drugs was increased year by year, among which the top three sales amounts were α-Glucosidase Inhibitors, Glinides and Biguanides.The top three DDDs from 2017 to 2019 were Acarbose, Metformin (imported), Metformin (domestic) and Saxagliptin.From 2017 to 2019, DDC of all kinds of oral hypoglycemic drugs was ＜100.From 2017 to 2019, the B/A of most oral hypoglycemic drugs was in the range of 0.5-1.5, the smallest was Acarbose, and the largest was Metformin (imported).Conclusion From 2017 to 2019, the use of oral hypoglycemic drugs in the Outpatient Department of Xianning Central Hospital is basically reasonable and economical.
		2021 Vol. 28 (20): 209-211 [Abstract] ( 44 ) HTML (28 KB) PDF (0 KB) ( 7 )

	212	Application of key observation room in the management of clinical psychology department
		HUANG Jian ZUO Hong-ying ZUO Xiao-yun ZOU Hai-yun XIE Gen-ying HU Xue-gen
		Objective To explore the application value of key observation rooms in the management of clinical psychology department.Methods The clinical data of 126 patients with depression treated in the Third People′s Hospital of Ji′an City from January 1, 2008 to December 31, 2019 were retrospectively collected.A total of 58 patients with depression treated in the Department of Psychology of the Third People′s Hospital of Ji′an City from January 1, 2008 to December 31, 2013 were included in the control group during the management period.A total of 68 patients with depression treated in the key observation room in the Department of Psychology of the Third People′s Hospital of Ji′an City from January 1, 2014 to December 31, 2019 were included in the observation group during the management period.The scores of suicide attitude, self-injury, suicide, medical disputes and patient satisfaction were compared between the two groups before intervention and 30 days after intervention.Results After 30 days of intervention, the questionnaire of suicide attitude (QSA) scores of two groups were higher than those before intervention, and the observation group was higher than the control group, and the differences were statistically significant (P＜0.05).After intervention,the incidence of self-injury, suicide, and medical disputes in the observation group were lower than those in the control group, and the differences were statistically significant (P＜0.05).After intervention, the total satisfaction rate of management in the observation group was 97.06%, which was higher than 79.31% in the control group, and the differences were statistically significant (P＜0.05).Conclusion The management effect of the key observation room in the clinical psychology department is significant, which can effectively alleviate the suicidal attitude of patients and reduce the incidence of self-harm and self-harm, and it is beneficial to reduce medical disputes and improve patient satisfaction, which is worthy of comprehensive application in clinical psychology department.
		2021 Vol. 28 (20): 212-214转218 [Abstract] ( 48 ) HTML (33 KB) PDF (0 KB) ( 6 )

	215	Application effect of feedforward control theory in nursing management of operating room
		CHEN Jie-shan SU Qian-xia ZHONG Cai-hua GU Qian-qian
		Objective To analyze the application effect of feedforward control theory in nursing management of operating room.Methods A total of 43 patients who underwent surgical treatment during routine nursing in the operating room of the Seventh People′s Hospital of Nanhai District, Foshan City from July 2018 to July 2019 were selected as the control group.Another 43 patients who received surgical treatment during the implementation of feedforward control theory in the operating room of the Seventh People′s Hospital of Nanhai District, Foshan City from August 2019 to August 2020 were selected as the observation group.The occurrence of nursing risk events, nursing quality scores of nursing staff and patients′ nursing satisfaction were statistically compared between the two groups.Results The total incidence of nursing risk events in the observation group (2.33%) was lower than that in the control group (18.60%), and the difference was statistically significant (P＜0.05).The scores of theoretical knowledge ([85.94±6.82]points), nursing work attitude ([86.08±6.93]points), risk management behavior ([87.15±6.02]points), writing quality of nursing documents([88.92±7.14]points),safety management([86.18±5.17]points),relevant legal knowledge([83.19±5.18]points)in the observation group were higher than those of the control group ([76.52±5.31],[76.84±6.24],[76.41±5.92],[75.16±6.10],[75.14±5.23],[76.19±5.15]points), and the differences were statistically significant (P＜0.05).The total nursing satisfaction of observation group (95.35%) was higher than that of control group (79.07%), and the difference was statistically significant (P＜0.05).Conclusion The application of feedforward control theory in operating room nursing management is effective, which can reduce the occurrence of nursing risk events, so as to provide patients with more high-quality and efficient operating room nursing services, and promote the improvement of nursing quality and nursing satisfaction.
		2021 Vol. 28 (20): 215-218 [Abstract] ( 34 ) HTML (35 KB) PDF (0 KB) ( 7 )

	219	Influence of low-temperature plasma sterilizer with full-process quality control management on the sterilization effect and work quality of the sterilization supply room
		HUANG Pei-zhen1 XING Gang2 HUANG Liu-ying1 HE Li-mei1 TAN Xin-xin3
		Objective To explore the effect of low-temperature plasma sterilizer with full-process quality control management on the sterilization effect and work quality of the equipment in the sterilization supply room.Methods From May 2019 to February 2020 (before the implementation of low-temperature plasma sterilizer combined with full-process quality control management), 320 medical devices in the sterilization supply room of Yunfu Hospital of Traditional Chinese Medicine were randomly selected as the control group.From March 2020 to December 2020 (after the implementation of low-temperature plasma sterilizers and full-process quality control management), 320 medical devices in the sterilization supply room of Yunfu Hospital of Traditional Chinese Medicine were randomly selected as the research group.The control group used the low-temperature plasma sterilizer with routine management, while the research group used the low-temperature plasma sterilizer with full-process quality control management.The sterilizing effect, working quality and management satisfaction of the sterilization supply room were compared between the two groups.Results The biomonitoring qualification rate of the research group (100.0%) was higher than that of the control group (76.8%),and the difference was statistically significant (P＜0.05).The unqualified rate of device recovery (1.56%), cleaning(0.94%), packaging (0.13%) and device distribution error (0.03%) in the research group were lower than those in the control group (9.06%, 8.13%, 9.69%, 5.63%), and the differences were statistically significant (P＜0.05).The total satisfaction of device management in the research group (95.00%) was higher than that in the control group (80.00%), and the difference was statistically significant (P＜0.05).Conclusion The combination of low-temperature plasma sterilizer and full-process quality control management enhances the sterilization effect and work quality of the equipment in the sterilization supply room, and improves the satisfaction of the hospital staff on the quality of the equipment.
		2021 Vol. 28 (20): 219-221转225 [Abstract] ( 30 ) HTML (34 KB) PDF (0 KB) ( 9 )

	222	Effect of implementing crisis nursing management theory on the delivery outcomes in puerperae
		LIU Xiao-yan
		Objective To explore the effect of implementing crisis nursing management theory on the delivery outcomes in puerperae.Methods A total of 108 women who delivered in Dalian Women and Children′s Medical Center from May 2018 to May 2020 were selected as the research objects.According to random number table method, they were divided into the control group and the observation group, with 54 cases in each group.The control group received routine nursing intervention, and the observation group received nursing intervention with crisis nursing management theory.The stage of labor, mode of delivery, postpartum complications, occurrence of adverse neonatal outcomes and maternal satisfaction with nursing were compared between the two groups.Results The first, second and third stages of labor in the observation group were shorter than those in the control group, and the differences were statistically significant (P＜0.05).The rate of natural delivery in the observation group was higher than that in the control group, the rate of cesarean section and vaginal delivery were lower than those in the control group, the difference of delivery mode between the two groups was statistically significant.The total incidence of postpartum complications and the total incidence of adverse neonatal outcomes were lower than those in the control group, and the differences were statistically significant (P＜0.05).The nursing satisfaction score of the observation group was higher than that of the control group, and the difference was statistically significant (P＜0.05).Conclusion The intervention of crisis nursing management theory in the process of childbirth can shorten the labor stages, improve the delivery outcome, and reduce the incidence of complications, so as to improve the satisfaction of the puerperae.
		2021 Vol. 28 (20): 222-225 [Abstract] ( 43 ) HTML (33 KB) PDF (0 KB) ( 7 )

	226	Application of electrical stimulation breathing training in pulmonary rehabilitation nursing of patients after lung cancer surgery
		LIU Ji-mei
		Objective To explore the application of electrical stimulation breathing training in pulmonary rehabilitation of patients after lung cancer surgery.Methods A total of 60 postoperative lung cancer patients admitted to Ganzhou Cancer Hospital from January 2019 to June 2020 were selected and divided into the control group and the test group according to the random number table method, 30 cases in each group.The control group received routine nursing combined with abdominal breathing training, and the test group received electrical stimulation breathing training on the basis of it.Both groups received 12 weeks of nursing care.The pulmonary function, 6-min walking distance and pulmonary rehabilitation were compared before nursing, 8 weeks after nursing, and 12 weeks after nursing.Results There were no significant difference in 1 s forced expiratory volume (FEV1), forced vital capacity (FVC) and 6-min walking distance between the two groups before nursing (P＞0.05).FEV1 and FVC were higher in the two groups after 8 and 12 weeks of nursing than before nursing, and FEV1 and FVC of the test group were higher than those of the control group,the differences were statistically significant (P＜0.05).After 8 and 12 weeks of nursing, the 6-min walking distance of the two groups were longer than before nursing, and the test group was longer than that of the control group, the differences were statistically significant significance (P＜0.05).The difference in dyspnea index between the two groups before nursing was not statistically significant (P＞0.05).After 8 weeks and 12 weeks of nursing, the dyspnea index of the two groups was lower than before nursing, and the test group was lower than that in the control group, the differences were statistically significant (P＜0.05).Conclusion Electrical stimulation breathing training can effectively improve the lung function and exercise endurance of patients after lung cancer surgery, thereby promoting postoperative pulmonary rehabilitation.
		2021 Vol. 28 (20): 226-228 [Abstract] ( 38 ) HTML (31 KB) PDF (0 KB) ( 6 )

	229	Effect of traditional Chinese medicine foot bath combined with basic nursing intervention on blood pressure and quality of life of patients with systolic hypertension
		XU Jing DAI Yu WU Ke-qin
		Objective To explore the effect of traditional Chinese medicine foot bath combined with basic nursing intervention on blood pressure and quality of life of patients with systolic hypertension.Methods A total of 100 patients with systolic hypertension admitted to the Second Department of Jiangxi Provincial People′s Hospital from February 2018 to February 2019 were selected as the research objects.According to the random number table method, they were divided into the control group and the observation group, 50 cases in each group.The control group was given basic nursing intervention, and the observation group was given traditional Chinese medicine foot bath nursing on the basis of the control group.Systolic blood pressure level and quality of life score before and after nursing were compared between the two groups.Results The systolic blood pressure of the two groups after nursing was lower than that before nursing, the systolic blood pressure of the observation group after nursing was lower than that of the control group, the differences were statistically significant (P＜0.05）.The scores of physiological function, physiological function, life vitality, social function, role function, cognitive function, mental health and total quality of life of the two groups after nursing were higher than those before nursing, the scores of physiological function, physiological function, vitality, social function, role function, cognitive function, mental health and total quality of life in the observation group were higher than those in the control group, the differences were statistically significant (P＜0.05）.Conclusion Traditional Chinese medicine foot bath can improve the blood pressure level and quality of life of patients with systolic hypertension, which is worthy of clinical application.
		2021 Vol. 28 (20): 229-231 [Abstract] ( 28 ) HTML (32 KB) PDF (0 KB) ( 6 )

	232	Influence of empathy nursing combined with routine nursing on patients with endometrial cancer
		TIAN Xiao-yu1 ZHANG Ying-yan2 JIANG Xue-mei1▲
		Objective To explore the effect of empathy nursing combined with routine nursing on patients with endometrial cancer.Methods A total of 80 patients with endometrial cancer admitted to the General Hospital of Northern Theater Command from August 2019 to August 2020 were selected as research subjects.According to the random paper method, they were divided into the control group and the observation group, 40 cases in each group.The control group adopted routine nursing, while in the observation group, empathy nursing measure was adopted on the basis of the control group.The level of hope score, coping style score, quality of life score, pain score of the two groups before and after nursing were compared.The satisfaction and compliance of the two groups were also compared.Results The level of hope scores, coping style scores, quality of life scores, and pain scores between the two groups before nursing were not statistically significant (P＞0.05).After nursing, the level of hope scores, coping style scores, and quality of life scores of the control group and observation group were higher than those of the same group before nursing, and the pain scores was lower than that of the same group before nursing;the patients′ level of hope score, coping style score, and quality of life score in the observation group were higher than those of the control group, and the pain score was lower than that of the control group, the differences were statistically significant (P＜0.05).The total satisfaction and compliance of the observation group were higher than those of the control group, the differences were statistically significant (P＜0.05).Conclusion The application of empathy nursing combined with routine nursing in patients with endometrial cancer can improve level of hope, coping style ability and quality of life, reduce pain scores, and enhance satisfaction and compliance of patients.
		2021 Vol. 28 (20): 232-235 [Abstract] ( 46 ) HTML (37 KB) PDF (0 KB) ( 6 )

	236	Application effect of regional puncture method combined with WeChat platform management during PICC catheterization of tumor patients
		WEN Qi-lian LI Ting LI Wei-zhen DENG Jiao
		Objective To explore the application effect of zone puncture method (ZIM) combined with WeChat platform management during PICC catheterization of tumor patients.Methods A total of 90 tumor patients admitted to Pingxiang People ′s Hospital from June 2019 to July 2020 were selected as the research objects, and were divided into group A(30 cases), group B (30 cases) and group C (30 cases) according to the random number table method.Group A used ZIM guided PICC catheter placement combined with conventional nursing intervention, group B used conventional ultrasound guided PICC placement combined with conventional nursing intervention, group C used ZIM ultrasound guided PICC placement combined with WeChat platform management, all three groups continuously intervened until after extubation.The incidence of postoperative complications, nursing satisfaction rate and self-care ability of the three groups were compared.Results The total incidence of complications in group A was lower than that in group B, the total incidence of complications in group B was higher than that in group C, and the total incidence of complications in group A was higher than that in group C, the differences were statistically significant (P＜0.05).The care total satisfaction of group A before discharge and after extubation was higher than that of group B, the care total satisfaction of group B was lower than that of group C, and the care total satisfaction of group A was lower than that of group C, the differences were statistically significant (P＜0.05).There was no statistically significant difference in the exercise of self-care agency (ESCA) scores of the three groups before the intervention (P＞0.05);compared with before the intervention, the ESCA scores of the three groups increased after the intervention, and the ESCA scores of group A were higher than that of group B，the ESCA scores of group B were lower than those of group C，and the ESCA scores of group A were lower than those of group C, the differences were statistically significant (P＜0.05).Conclusion ZIM combined with WeChat platform management can effectively reduce the occurrence of complications during PICC catheterization of tumor patients and improve their self-care ability.
		2021 Vol. 28 (20): 236-238 [Abstract] ( 38 ) HTML (33 KB) PDF (0 KB) ( 7 )

	239	Study on the effect of predictive nursing in patients with recurrent diabetic foot ulcer
		HE Qin ZHU Qian DING Lin XIN Hong-xia▲
		Objective To analyze the effect of predictive nursing in patients with recurrent diabetic foot (DF) ulcer.Methods A total of 80 patients with DF ulcer recurrence admitted to the Second Affiliated Hospital of Nanchang University from January to December 2019 were selected and divided into the control group and the observation group according to random number table method, 40 cases in each group.The control group was given routine nursing and the observation group was given the method of predictive nursing.The good nursing degree, blood glucose, quality of life,incidence of amputation and disease recurrence rate of the two groups were compared.Results The good degree of foot care in observation group was higher than that in control group, the difference was statistically significant (P＜0.05).There was no significant difference the blood glucose index between the two groups before nursing (P＞0.05).The blood sugar index of two groups after nursing was lower than that before nursing, the blood glucose index after nursing in the observation group was lower than that in the control group, the differences were statistically significant (P＜0.05).Quality of life before nursing between the two groups showed no statistically significant difference (P＞0.05).The quality of life scores of the observation group and the control group after nursing were higher than those before nursing, the quality of life score of the observation group was higher than that of the control group, the difference were statistically significant (P＜0.05).The incidence of amputation and disease recurrence in the observation group were lower than those in the control group, and the differences were statistically significant (P＜0.05).Conclusion Predictive nursing can effectively reduce the recurrence rate of DF ulcer, improve the treatment effect and have clinical application value.
		2021 Vol. 28 (20): 239-241转261 [Abstract] ( 39 ) HTML (34 KB) PDF (0 KB) ( 7 )

	242	Application of integrated positive pressure needle-free indwelling needle in intravenous therapy of drug dddicts
		WEN Wen TONG Li-ling▲ WU Dan
		Objective To explore the application of integrated positive pressure needle-free indwelling needle in intravenous therapy of drug addicts.Methods A total of 150 drug addicts admitted to Affiliated Haikou Hospital of Xiangya Medical College, Central South University from January 2018 to December 2019 were selected as the research objects and divided into the observation group (50 cases), and the control group 1 (50 cases), and control group 2 (50 cases) according to the random number table method.The observation group：was integrated positive pressure needle-free indwenting-needle infusion;control group 1 was used 24 G closed indwerable needle connected with heparin cap infusion;control group 2 was used closed indwelling needle connection separator diaphragm without needle joint infusion.The duration of indwelling and complications during indwelling were compared among the three groups (blocked tube,needle puncture wound, intraductal blood loss, phlebitis, extravasation, and extravasation at puncture point).Results The indwelling time of the needle in the observation group, the control group 1 and the control group 2 were (4.89±0.21) d, (3.32±0.28) d and (3.87±0.28) d respectively, which was longer than that in the control group 1 and the control group 2, the differences were statistically significant (P＜0.05).The proportion of cases in the observation group, the control group 1 and the control group 2 during the indwelling of the indwelling needle were 4%, 0%,10%;28%,16%,72%;28%,16%, 72% respectively.The incidence of blocked tubes, needle stick injuries, and intrathecal blood recovery in the observation group were lower than that in the control group 1 and 2, with statistical differences (P＜0.05).The propotion of the cases of phlebitis, extravasation and blood extravasation at the puncture point during indwelling needle in the observation group, the control group 1 and the control group 2 were 16%, 6%, 8%;12%, 12%, 16%;12%, 12%, 16% respectively, the phlebitis, extravasation, and extravasation at puncture point in the observation group were compared with those in control group 1 and control group 2 showing no statistically significant differences (P＞0.05).Conclusion Integrated positive pressure needle-free indwelling needle indwelling needle can prevent tube plugging, prolong catheter indwelling time, reduce vascular damage caused by repeated puncture and puncture times, protect blood vessels of patients, and reduce the occurrence of phlebitis.
		2021 Vol. 28 (20): 242-244转265 [Abstract] ( 28 ) HTML (34 KB) PDF (0 KB) ( 6 )

	245	Clinical experience of holistic responsibility nursing in patients with viral keratitis
		WANG Hai-ling DONG He
		Objective To explore the clinical value of holistic responsibility nursing mode in the nursing of patients with viral keratitis.Methods A total of 94 patients with viral keratitis treated in Dalian Third People′s Hospital from September 2016 to December 2019 were selected as the study subjects, and divided into the control group and the study group using random number table method, 47 cases in each group.The control group was treated with conventional nursing intervention, and the study group was treated with integrated responsibility nursing intervention.The changes of Hamilton anxiety (HAMA), Hamilton depression (HAMD) scale scores, quality of life scores and satisfaction were compared between the two groups before and after nursing.Results There were no significant differences in HAMA and HAMD score between the two groups before treatment (P＞0.05).After treatment, HAMA and HAMD scores of the two groups were lower than before treatment, HAMA and HAMD scores in the study group were lower than those in the control group, the differences were statistically significant (P＜0.05).There was no significant difference in quality of life score between the two groups before treatment (P＞0.05).The quality of life scores after treatment were higher than before treatment, the quality of life score of the study group was higher than that of the control group after treatment, the differences were statistically significant (P＜0.05).The total nursing satisfaction of the study group (91.49%)was higher than that of the control group (74.47%), and the difference was statistically significant (P＜0.05).Conclusion The implementation of holistic responsibility nursing in the nursing of patients with viral keratitis is helpful to improve the negative emotions of patients and improve the quality of life of patients, with higher nursing satisfaction and higher clinical value.
		2021 Vol. 28 (20): 245-247 [Abstract] ( 37 ) HTML (32 KB) PDF (0 KB) ( 8 )

	248	Influence of WeChat continuous nursing on the functional recovery of patients after clavicle fracture
		FU Xiao-lan LIU Ai-hua CHEN Qun-ping WAN Shao-hua
		Objective To explore the influence of WeChat continuous nursing on the functional recovery of patients after clavicle fractures.Methods A total of 68 postoperative clavicle fracture patients who were admitted to Fuzhou Hospital of Traditional Chinese Medicine in Jiangxi Province from September 2019 to September 2020 were selected.They were divided into two groups according to random number table method, 34 cases in each group.In the control group,routine discharge guidance and telephone follow-up were used, and in the observation group, WeChat continuous nursing was added.The functional exercise compliance, shoulder joint function recovery and nursing satisfaction of the two groups of after hospital discharge were analyzed.Results The functional exercise compliance of the observation group was higher than that of the control group, and the difference was statistically significant (P＜0.05）.Before the intervention,there were no statistically significant differences between the two groups of shoulder pain and disability index (SPADI) (P＞0.05）.After the intervention, the SPADI score of the observation group was (32.15±2.14) points, which was lower than that of the control group of (41.44±3.27) points, with statistical difference (P＜0.05).The total nursing satisfaction of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion WeChat continuous nursing can promote the recovery of shoulder joint function of patients with clavicle fractures, enhance their compliance with functional exercises after hospital discharge, and increase nursing satisfaction.
		2021 Vol. 28 (20): 248-250 [Abstract] ( 43 ) HTML (32 KB) PDF (0 KB) ( 7 )

	251	Application of ″one department，one characteristic″ nursing in patients with chronic kidney disease at risk of malnutrition
		ZHOU Hui-ting LI Bei SHI Xiao-yan▲ HU Fang
		Objective To explore the application effect of ″one department，one characteristic″ nursing in patients with chronic kidney disease (CKD) with malnutrition risk.Methods 30 patients with CKD at risk of malnutrition admitted to Nanjing Hospital of Chinese Medicine from January to June 2020 were selected as the control group.Another 30 cases of CKD patients with malnutrition risk admitted to Nanjing Hospital of Chinese Medicine from July to December 2020 were selected as the observation group.The control group was given routine nursing intervention, and the observation group was given ″one subject one characteristic″ nursing mode on the basis of the control group.The renal function, nutritional status, complications and self-management of the two groups were compared.Results After the intervention,serum creatinine, blood urea nitrogen and 24-hour urinary protein in the observation group were lower than those in the control group, and the differences were statistically significant (P＜0.05）.After the intervention, the nutritional status of the observation group was better than that of the control group, and the serum albumin and prealbumin indexes of the observation group were higher than those of the control group, the differences were statistically significant (P＜0.05）.The total complication rate of the observation group was 16.66%, lower than 53.33% of the control group, the difference was statistically significant (P＜0.05）.There was no significant difference in the scores of self-management behavior between the two groups before intervention (P＞0.05）.The scores of self-management behavior of the two groups after intervention were higher than those before intervention, the self-management behavior score of the observation group was higher than that of the control group, and the differences were statistically significant (P＜0.05）.The nursing total satisfaction of the observation group was 100.00%, higher than 80.00% of the control group, the difference was statistically significant (P＜0.05）.Conclusion For patients with CKD at risk of malnutrition ″one department, one characteristic″nursing can effectively improve the nutritional status of patients, strengthen the self-management ability of patients, and has good safety, which is worthy of promotion.
		2021 Vol. 28 (20): 251-254 [Abstract] ( 46 ) HTML (38 KB) PDF (0 KB) ( 7 )

	255	Application of post-operative timing nursing model in promoting the recovery of gastrointestinal function of patients after abdominal operation
		OU Zhi-ping
		Objective To explore application of postoperative timing nursing mode in gastrointestinal function recovery of patients undergoing abdominal surgery.Methods A total of 80 cases with abdominal operation from May 2018 to October in Fuzhou First People′s Hospital, Jiangxi Province were selected as research objects, divided into the control group and the observation group according to random number table method, 40 cases in each group.The control group was intervened by traditional nursing, and the observation group was intervened by postoperative selective nursing.The scores of gastrointestinal related indexes, the first intestinal ventilation, defecation and hospital stay of the two groups were compared, and the nursing satisfaction of the two groups was also compared.Results After nursing, the abdominal distension，exhaust/defecation and pain scores of the observation group were lower than those of the control group, the first defecation time, exhaust time and length of stay in hospital of the observation group were shorter than those of the control group;the nursing satisfaction scores of the observation group were higher than that of the control group, the differences were statistically significant (P＜0.05).Conclusion The application of postoperative selective nursing for patients with abdominal surgery can promote the early recovery of gastrointestinal function, but also can improve the satisfaction of patients with nursing.
		2021 Vol. 28 (20): 255-257 [Abstract] ( 42 ) HTML (31 KB) PDF (0 KB) ( 9 )

	258	Application effect of comprehensive nursing intervention in patients with gallstones
		CHEN Chun-mei
		Objective To explore the application effect of comprehensive nursing intervention in patients with gallstones.Methods A total of 100 patients with gallstones admitted to Nanjing Gaochun People′s Hospital from June 2019 to June 2020 were selected as the research subjects.All patients were divided into the reference group (50 cases) and the nursing group (50 cases) according to the method of rolling dice.The reference group applied routine basic nursing care, while the nursing group adopted comprehensive nursing intervention on this basis.The two groups of gallstone patients were compared before and after nursing for anxiety, depression, postoperative pain, hospital stay, and nursing satisfaction and postoperative complications.Results The self-rating anxiety scale (SAS), self-rating depression scale(SDS) score, and visual analogue scale (VAS) score of the nursing group after nursing were lower than those of the reference group, and the differences were statistically significant (P＜0.05）.The hospital stay of the nursing group was shorter than that of the reference group, and the difference was statistically significant (P＜0.05）.The nursing satisfaction score of the nursing group was higher than that of the reference group, and the difference was statistically significant (P＜0.05）.The total incidence of complications in the nursing group was lower than that in the control group, the difference was statistically significant (P＜0.05）.Conclusion The clinical effect of comprehensive nursing in the clinical nursing of patients with gallstones is very good.It can not only shorten the hospital stay, reduce the incidence of complications, but also improve the psychological mood of patients, relieve pain, and increase clinical nursing satisfaction.
		2021 Vol. 28 (20): 258-261 [Abstract] ( 43 ) HTML (36 KB) PDF (0 KB) ( 8 )

	262	Application effect of all-round fine nursing model in elderly patients with severe pneumonia
		LU Hong
		Objective To explore the application effect of all-round fine nursing model in elderly patients with severe pneumonia.Methods A total of 94 elderly patients with severe pneumonia admitted in Honghu Hospital of Traditional Chinese Medicine in Hubei Province from March 2017 to April 2019 were selected as the research objects, and they were divided into the routine group(47 cases)and the fine group(47 cases)according to the random number table method.The routine nursing was carried out in routine group, while the all-round fine nursing mode was adopted in the fine group.The mortality during hospitalization, duration of mechanical ventilation and length of hospital stay were compared, and the changes of mental state at admission and on the day of discharge were compared, then the complications during hospitalization was also compared.Results There was no significant difference in mortality between the routine group (14.89%) and the fine group (6.38%) (P＞0.05).The time of mechanical ventilation were (7.58±1.52) and hospitalization (21.35±3.14)d in the fine group shorter than those in the routine group of (10.69±2.26) and (27.95±4.06)d respectively, and the differences were statistically significant (P＜0.05).The scores of self-rating anxiety scale (SAS) was(45.62±4.91) score and self-rating depression scale (SDS) was (46.89±5.03) score on the day of discharge in the fine group were lower than those in the routine group of (50.84±4.72) and (52.07±5.36) score respectively, and the differences were statistically significant (P＜0.05).The SAS and SDS scores of the two groups on the day of discharge were lower than those at admission, and the differences were statistically significant (P＜0.05).The total incidence rate of complications in the fine group (8.51%) was lower than that of the routine group (27.66%), and the difference was statistically significant (P＜0.05).Conclusion The all-round fine nursing mode for elderly patients with severe pneumonia can significantly shorten the time of mechanical ventilation and hospitalization, improve the psychological state and reduce the occurrence of complications, with good application effect.
		2021 Vol. 28 (20): 262-265 [Abstract] ( 40 ) HTML (33 KB) PDF (0 KB) ( 6 )

	266	Application effect of targeted nursing intervention in the treatment of chronic cholecystitis complicated with gallstones by Xiaoyan Rongshi tang
		XIE Yu-niang
		Objective To investigate the application effect of nursing intervention in the treatment of chronic cholecystitis complicated with gallstones by Xiaoyan Rongshi Decoction.Methods A total of 80 patients with chronic cholecystitis combined with gallstones admitted to Ganzhou People′s Hospital in Jiangxi Province from June 2019 to March 2020 were selected as study subjects, they were divided into the control group and the implementation group by random number table method, 40 cases in each group.Both groups were treated with Xiaoyan Rongshi Decoction for chronic cholecystitis.Routine nursing intervention was used in the control group and targeted nursing intervention was used in the implementation group.With total effective rate, main symptom (liver area taps, shoulder pain, right rib pain, nausea and vomiting, and stool junction) response rate, different parts (biliary calculi, within the liver and gallbladder stones)calculi discharge rate, nursing satisfaction, quality of life and psychological rating scale were compared between two groups.Results The total effective rate in the implementation group (97.50%) was higher than that in the control group(80.00%), and the difference was statistically significant (P＜0.05).The remission rate of main symptoms (percussion pain in liver and gallbladder area, shoulder distension, right costal pain, nausea and vomiting, and stool knot) in the implementation group was higher than that in the control group, and the difference was statistically significant (P＜0.05).The remission rate of stone excretion in different parts of the implementation group (biliary calculi, intrahepatic calculi and cholecystolithiasis) was higher than that in the control group, and the difference was statistically significant (P＜0.05).Nursing total satisfaction, quality of life and psychological scale scores of the implementation group were higher than those of the control group, and the differences were statistically significant (P＜0.05).Conclusion Xiaoyan Rongshi Decoction for the treatment of chronic cholecystitis with gallstones and targeted nursing intervention of the clinical efficacy is significant.
		2021 Vol. 28 (20): 266-269转273 [Abstract] ( 39 ) HTML (40 KB) PDF (0 KB) ( 6 )

	270	Analysis of preventive nursing of cervical cancer complicated with intermuscular vein thrombosis of calf
		XUE Yun-qin NIAN Jin-xia LI Zhen-ming ZHENG Wei-xi CHEN Xi-ping
		Objective To explore the clinical effect of nursing intervention during surgery for patients with cervical cancer complicated with intermuscular venous thrombosis of calf.Methods A total of 172 patients with cervical cancer who underwent surgery at the Fujian Maternity and Child Health Hospital from May 2017 to March 2020 were selected as research subjects.These patients were divided into the control group (n=129) and the observation group (n=43) according to the order of admission.All selected patients were treated with cervical conization.The control group took conventional nursing measures, while the observation group adopted preventive nursing measures before surgery besides conventional nursing.The total incidence of complications, nursing satisfaction, comfort score, skeletal and short musculoskeletal function assessments (SMFA) score and quality of life score between the two groups were compared.Results The total incidence of complications in the observation group was lower than that in the control group, with statistical difference (P＜0.05).The total nursing satisfaction and comfort scores of the observation group were higher than those in the control group, with statistical differences (P＜0.05).Before the intervention, there were no significant difference in the scores of the upper and lower extremity SMFA between the two groups (P＞0.05).After the intervention, the upper and lower extremity SMFA scores of the observation group were higher than those of the control group, with statistical differences (P＜0.05).Quality of life scores in the dimensions of physiology, psychology, social relations, and environment of the observation group were higher than those the control group, with statistical differences (P＜0.05).Conclusion Cervical cancer combined with intermuscular venous thrombosis of the calf, through reasonable preoperative evaluation, perioperative thrombosis prevention and other nursing measures, can well prevent the complications caused by thrombosis.
		2021 Vol. 28 (20): 270-273 [Abstract] ( 45 ) HTML (35 KB) PDF (0 KB) ( 8 )

	274	Effect of early limb movement combined with intermittent pneumatic compression devices to prevent deep vein thrombosis after major orthopedic surgery in the elderly
		LIN Wen-hui ZHANG Xiu-xian HUANG Ai-hong
		Objective To explore the effect of early limb movement combined with intermittent pneumatic compression devices (IPCD) to prevent deep vein thrombosis (DVT) after major orthopedic surgery in the elderly.Methods A total of 96 cases of total hip arthroplasty (THA), total knee arthroplasty (TKA) and hip fractures surgery (HFS) patients accepted from the People′s Hospital of Puning City, Guangdong Province from January to December 2018 were selected as the control group.103 cases of THA, TKA and HFS patients accepted from the People′s Hospital of Puning City,Guangdong Province from January to December 2019 were selected as the study group.The control group was given routine nursing, and the study group was implemented early limb exercises combined with IPCD on the basis of the control group to prevent DVT.The incidence of DVT and the application rate of anticoagulant drugs were compared between the two groups.Results The incidence of DVT of the study group at the 3 and the 7th days after operation were lower than those of the control group, and the differences were statistically significant (P＜0.05).The application rates of anticoagulant drugs of the study group at the 3, 5 and the 10th days after operation were lower than those of the control group, and the differences were statistically significant (P＜0.05).Conclusions Early limb movement combined with IPCD can effectively reduce the incidence of DVT after major orthopedic surgery in the elderly and reduce the application rate of anticoagulant drugs.It is worth applying.
		2021 Vol. 28 (20): 274-276转封三 [Abstract] ( 46 ) HTML (38 KB) PDF (0 KB) ( 7 )

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