胸腔积液Xpert MTB/RIF UItra检测对结核性胸膜炎临床诊断的价值分析

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (30 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the value of Xpert MTB/RIF UItra (referred to as Xpert UItra) detection of pleural effusion in the clinical diagnosis of tuberculous pleurisy.Methods From June 2018 to June 2020, 120 patients with suspected tuberculosis pleurisy admitted to Jiangxi Chest Hospital were selected as the research subjects.The pleural effusion of all patients was collected.According to pathological examination as the gold standard, the patients were divided into confirmed group (58 cases), suspected group (42 cases) and non-tuberculosis group (20 cases).Xpert MTB/RIF (referred to as Xpert) and Xpert UItra were used to detect the pleural effusion of patients in the three groups respectively, and the sensitivity, specificity and accuracy of the two detection methods were discussed.Results In the confirmed group, the positive rate of Xpert UItra test was 96.55%, which was higher than that of Xpert (82.76%), with statistical difference (P＜0.05).In the suspected diagnosis group, the positive rate of Xpert UItra detection was 66.67%,which was higher than that of Xpert (45.24%), with statistical difference (P＜0.05).In the non-tuberculosis group, the positive rate of Xpert UItra detection was 5.00%, lower than that of Xpert (30.00%), and the difference was statistically significant (P＜0.05).The sensitivity, specificity and accuracy of Xpert UItra for tuberculous pleurisy were 96.50%,95.00% and 96.15%, which were all higher than those of Xpert (82.76%, 70.00% and 79.49%), and the differences were statistically significant (P＜0.05).Conclusion In the diagnosis of tuberculous pleurisy, the use of Xpert Uitra for the diagnosis of pleural effusion in patients has high accuracy, sensitivity and specificity, and has high diagnostic value.

Key words： Pleural effusion Xpert MTB/RIF UItra Tuberculous pleurisy Diagnostic value

Received: 14 January 2021

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I20/44

[1]	毕占友，郝军，陈忠建，等.微卡联合化学药物治疗多耐药结核病临床疗效分析[J].陕西医学杂志，2018，47（4）：509-511.
[2]	董静，贾红彦，潘丽萍，等.胸腔积液miRNA 检测用于结核性胸膜炎诊断的研究进展[J].中华结核和呼吸杂志，2020，43（8）：685-687.
[3]	余卫业，谭卫国，罗一婷，等.2018 WHO 全球结核报告：全球与中国关键数据分析[J].新发传染病电子杂志，2018，3（4）：228-233.
[4]	李虹泽，曹锋，樊毅，等.3 种方法联合检测在诊断结核性胸膜炎中的应用价值[J].临床肺科杂志，2018，23（11）：1967-1970.
[5]	吴龙章，钟炳棠，刘燕文，等.对《结核病诊断细菌学检验规程》的一点看法[J].中国防痨杂志，2012，34（3）：192-193.
[6]	高飞，高艳，刘斌，等.应用ROC 曲线评价结核抗体蛋白芯片法对老年结核性胸膜炎的诊断价值[J].中华保健医学杂志，2017，19（4）：316-318.
[7]	Chakravorty S，Simmons AM，Rowneki M，et al.The New Xpert MTB/RIF Ultra：Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing[J].mBio，2017，8（4）：e00812-817.
[8]	俞计明，汪晔，沈惊雷，等.结核分枝杆菌rpoB 基因和突变检测对结核性胸膜炎诊断价值研究[J].中国卫生检验杂志，2017，27（1）：43-45.
[9]	李文博，刘超，孙扬，等.探讨Gene Xpert MTB/RIF 检查在结核性胸膜炎诊断中的价值[J].河北医学，2019，25（9）：1496-1499.
[10]	孟素华.Gene Xpert MTB/RIF 检测技术在结核性胸膜炎诊断中的应用价值[J].中国防痨杂志，2019，41（9）：1005-1008.
[11]	张芸，姜广路，王冲，等.经内科胸腔镜胸膜病变活检对结核性胸膜炎的诊断价值[J].中国防痨杂志，2020，42（11）：1158-1164.
[12]	高漫，白广红，周祎，等.不同检测方法在结核性脑膜炎诊断中的应用价值[J].中国防痨杂志，2019，41（4）：463-465.
[13]	吴迪，林友飞，陈晓红，等.白介素27 和腺苷脱氢酶单独及联合检测对结核性胸膜炎诊断价值[J].中国防痨杂志，2019，41（12）：1246-1251.
[14]	宋晓东，路希维，徐齐峰，等.白细胞介素-27、腺苷脱氨酶及结核抗体在结核性胸膜炎患者中的诊断价值[J].中国医师进修杂志，2019，42（6）：514-517.
[15]	王少华，杨翰，李爱芳，等.三种实验方法检测胸腔积液对结核性胸膜炎的诊断价值分析[J].现代检验医学杂志，2019，34（3）：104-108.