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2018 Vol. 25, No. 30
Published: 2019-10-28
4
Comparison of the effect of automated peritoneal dialysis and continuous renal replacement therapy in the treatment of severe acute pancreatitis
WU Jing;MA Guo-ying;CHEN Shuang;CUI Meng-bi;YANG Yu-qi;ZHA Yan
Objective
To compare the effect of automated peritoneal dialysis(APD)and continuous renal replacement therapy(CRRT)in the treatment of severe acute pancreatitis(SAP).
Methods
The clinical data of 76 patients with SAP diagnosed in Guizhou Provincial People′s Hospital and received blood purification therapy from October 2012 to December 2017 were retrospectively analyzed.According to the different treatment,they were divided into the APD group(39 cases)and the CRRT group (37 cases).The relief times of abdominal pain and distension,recovery times of serum and urine amylase levels were compared between the two groups,the changes of Balthazar CT score,APACHEⅡscore,the levels of interleukin-6(IL-6),C-reactive protein(CRP),procalcitonin(PCT)and tumour necrosis factor α(TNF-α)were compared at the 3 and 7 days after treatment.
Results
The relief times of abdominal pain and distension and recovery times of amylase levels in the APD group were significant shorter than those in the CRRT group,with significant difference(P＜0.05).The Balthazar CT score,APACHE Ⅱ score,the level of IL-6,CRP,PCT and TNF-α in the APD group were lower than those in the CRRT group,with significant difference(P＜0.05).
Conclusion
APD in the clinical treatment of SAP is significant effective,and which is worthy for popularizing application.
2018 Vol. 25 (30): 4-07 [
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] (
107
)
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8
Study on extraction technology of Shangkejiedu Granules
WANG Xiao-xin;WEI Yu-yan;HE Ke
Objective
To optimize the optimal extraction technology of Shangkejiedu Granules.
Methods
The dry extract mass fraction and chlorogenic acid mass fraction were taken as investigation indicators,and the test results were weighted comprehensive scores,among which the dry extract weight coefficient was 0.7,and the chlorogenic acid weight coefficient was 0.3.By investigating four single factors of water addition amount(A),soaking time(B),decoction time(C)and decoction times(D),the orthogonal test level was determined,the best extraction technology was screened,and the extraction technology was verified.
Results
The best extraction technology of Shangkejiedu Granules was A
2
B
3
C
2
D
2
,that was adding 24 times water,soaking for 45 minutes,decocting twice for 1 hour each time.The average values of dry extract mass fraction and chlorogenic acid mass fraction were 0.31 g/g and 5.44 mg/g,RSD was 1.9%and 3.8%respectively.
Conclusion
This technology is simple,stable and feasible,and can be applied to subsequent experimental research and industrial production.
2018 Vol. 25 (30): 8-11 [
Abstract
] (
134
)
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12
Influence of Berberine on PI3K/Akt/eNOS signal transduction pathway in thoracic aorta of type 2 diabetic rats
FENG Fen;TAN An-xiong;DENG Ji-xiang;ZHOU Bin
Objective
To observe the influence of Berberine on glucose and lipid metabolism and PI3K/Akt/eNOS signaling pathway of thoracic aorta in diabetic rats,and to investigate the possible protective mechanism of Berberine on macroangiopathy.
Methods
A total of 60 SD rats were randomly divided into the normal group (n=10)and the experimental group (n=50).The model of type 2 diabetes mellitus was established by intraperitoneal injection of Streptozotocin combined with high-fat and high-sugar diet.The diabetic rats were randomly divided into the model group (n=10),the Metformin group(n=10),and the Berberine group(n=10).The Metformin group and the Berberine group were given Berberine and Metformin respectively,the normal group and the model group were given normal saline by oral gavage.After 8 weeks,fasting blood glucose (FBG),serum concentrations of triglyceride (TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-c),low density lipoprotein cholesterol(LDL-c)and nitric oxide (NO)were measured.The histological morphology of the thoracic aorta was observed by HE staining,and the protein expression of p-PI3K-p85,p-Akt and p-eNOS was detected by Western blotting.
Results
The levels of FBG,TC,TG and LDL-c in the model group,the Berberine group and the Metformin group were higher than those in the normal group,the levels of HDL-c and NO,the expression of p-PI3K-p85,p-Akt and p-eNOS in thoracic aorta in the model group,the Berberine group and the Metformin group were lower than those in the normal group,with significant difference (P＜0.01).The levels of FBG,TC,TG and LDL-c in the Berberine group and the Metformin group were lower than those in the model group,the levels of HDL-c and NO,the expression of p-PI3K-p85,p-Akt and p-eNOS in thoracic aorta in the Berberine group and the Met-formin group were higher than those in the model group,with significant difference(P＜0.01).Compared with the model group,the macrovascular endothelium injury in the Berberine group and the Metformin group was relieved.
Conclusion
The protective effect of Berberine on macroangiopathy in diabetic rats may be related to improving glucose and lipid metabolism and activating PI3K/Akt/eNOS signaling pathway.
2018 Vol. 25 (30): 12-15转19 [
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117
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16
Expression study of Notch signal pathway in lymphocytes of burn infected patients
NI Shao-jun;LEI Yue;XU Qiu-yue;WANG Cheng;LIU Long-ling
Objective
To discuss the role and mechanism of Notch signal pathway regulating lymphocyte of patients with burn infection,to explore the immunology of burn infection and to provide experimental foundation on finding out the potential treatment means.
Methods
A total of 15 cases of burn infection admitted by the burn department of our hospital from July 2016 to July 2017 were selected as the burn infection group,and 15 healthy subjects who underwent health examination in our hospital during the same period were selected as the control group.Fluorogenic quantitative PCR (real time PCR,RT-PCR)and western blot were used to detect Notch 1 and Notch 2 in peripheral blood lymphocyte (PBL)in the two groups from gene transcription level and protein level.
Results
mRNA and protein expressions of Notch 1 and Notch 2 in PBL in the burn infection group were significantly higher than that in the control group (P＜0.05).
Conclusion
After Notch signal pathway of patients with burn infection is activated,it may be related to the antiinflammatory reaction.
2018 Vol. 25 (30): 16-19 [
Abstract
] (
119
)
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20
Expression and significance of Snail protein in patients with intrahepatic cholangiocarcinoma
ZHU Meng;SUN Wu-gang
Objective
To explore the expression and significance of Snail protein in patients with intrahepatic cholangiocarcinoma.
Methods
A total of 72 patients with intrahepatic cholangiocarcinoma from March 2011 to February 2016 in Center Hospital of Yuncheng City were selected as the research object.Immunohistochemistry was used to detect the patient′s tissues.The expression of Snail protein in the cancer tissues and adjacent tissues,the relationship between the expression of Snail protein and the clinicopathological factors,and the total survival rate and the total recurrence rate of the patients were observed.
Results
The immunohistochemical score of the tissue was (2.8±0.8)points,which was significantly higher than that of the adjacent tissues([0.9±0.8]points)(P＜0.05).The high expression rate of Snail protein in cancer tissues was 45.8%,which was significantly higher than that in adjacent tissues(16.7%)(P＜0.05).There were significant differences in TNM staging,microvascular invasion and recurrence between different Snail protein (P＜0.05).Multivariate analysis showed that there was a significant difference in the overall survival rate and total recurrence rate of microvessels and the high expression or low expression of Snail protein(P＜0.05).
Conclusion
The expression of Snail protein in the cancer tissues of the patients with intrahepatic cholangiocarcinoma is higher than that in the adjacent tissues,and the expression of Snail protein can be used as an indicator of the prognosis of the patients with intrahepatic cholangiocarcinoma.
2018 Vol. 25 (30): 20-22转26 [
Abstract
] (
130
)
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23
Influence of Minocycline combined with Metronidazole Film on periodontal status and inflammatory factors in patients with periodontal disease
ZHANG Xue-mei;ZHANG Yuan-qin;LIU Guo-ping;YUAN Qun
Objective
To investigate the level of inflammatory factors and periodontal status of periodontal disease patients treated with Minocycline combined with Metronidazole.
Methods
A total of 98 patients with periodontal disease admitted to our hospital from May 2016 to January 2018 were selected as the study subjects.According to the different treatment methods,they were divided into the reference group(n=49)and the research group(n=49).The control group was treated with Minocycline Hydrochloride Ointment,and the study group was treated with Metronidazole combined with Minocycline Hydrochloride Ointment.The levels of inflammatory factors,clinical efficacy rate and periodontal status of the two groups were compared.
Results
There was no statistically significant difference in the level of IL-6 and CRP between after treatment and before treatment in the control group (P＞0.05).There was no statistical difference of IL-6 level after treatment compared with before treatment and CRP level in the study group after treatment was significantly lower than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,there was no statistically significant difference in the level of IL-6 between the study group and the control group (P＞0.05).After treatment,the CRP level of patients in the study group was significantly lower than that of the control group,and the difference was statistically significant(P＜0.05).The clinical efficacy rate of the patients in the study group was 93.88%,which was higher than that in the control group(77.55%),and the difference was statistically significant(P＜0.05).The periodontal conditions such as gingival index,periodontal pocket depth,gingival bleeding index and plaque index in the study group were lower than those in the control group,and the difference was statistically significant(P＜0.05).
Conclusion
The treatment effect of Minocycline combined with Metronidazole in the treatment of patients with periodontal disease is good,which can not only make inflammatory factor levels drop,but also make periodontal condition of the patient markedly improved,it can play a certain role in promoting the quality of life of patients.
2018 Vol. 25 (30): 23-26 [
Abstract
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140
)
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27
Comparison of antibacterial effect in vitro of Hongteng Enema Decoction and Decoction-free Granules
JIANG Li;LI Yue-ting;HU Jun;LI Yuan;CHEN Hui
Objective
To compare the antibacterial effects in vitro of Hongteng Enema Decoction and Decoction-free Granules.
Methods
The paper-diffusion method was used to determine the in vitro antibacterial activity of Hongteng Enema Decoction and Decoction-free Granules on Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa and Candida albicans.The antibacterial effects of the two different dosage forms were examined by measuring the diameter of the inhibition zone.
Results
Hongteng Enema Decoction and Decoction-free Granules had no antibacterial effects on Candida albicans.For Staphylococcus aureus and Escherichia coli,the diameter of the inhibition zone of Hongteng Enema Decoction was bigger than that of Decoction-free Granule,and there was a significant difference between them (P<0.05).For Pseudomonas aeruginosa,the diameter of the inhibition zone of Hongteng Enema Decoction was lower than that of Decoction-free Granule,and there was a significant difference between them(P<0.05).Conclusion Hongteng Enema Decoction and Decoction-free Granule have similar antibacterial effects in vitro.The antibacterial effect of Hongteng Enema Decoction against Staphylococcus aureus and Escherichia coli is better than that of Decoction-free Granule.For Pseudomonas aeruginosa,the antibacterial effects of Hongteng Enema Decoction-free Granule is better than that of the Hongteng Enema Decoction.
2018 Vol. 25 (30): 27-29 [
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112
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30
Synthesis of compound amino acid iron,zinc and copper complexes and their antitumor and the study on the antibacterial activities
WU Jing
Objective
To prepare complexes of iron,copper and zinc with complex amino acids,and to study the antitumor and antibacterial effects of the three complexes.
Methods
The MTT method was used to determine the IC
50
of the complex amino acids and their complexes on A
549
and HepG2,and the inhibitory effects of the complexes on Salmonella,Staphylococcus aureus and Escherichia coli were investigated by double dilution.
Results
The IC
50
of A
549
were 268.6,200.9,193.7 and 162.8 μmol/L respectively,and IC
50
for HepG2 were 183.8,132.3,136.8 and 98.5 μmol/L respectively.The MIC of Salmonella were 1.00,0.50,0.50,0.50 mg/ml respectively,and MIC for Staphylococcus aureus were 0.50,0.25,0.25 and 0.25 mg/ml respectively,and the MIC of Escherichia coli were 1.00,0.50,0.50 and 0.50 mg/ml respectively.
Conclusion
The antibacterial and antitumor activities of the three complexes are better than that of the compound amino acids.
2018 Vol. 25 (30): 30-32 [
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135
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33
Influence of electroacupuncture combined with biofeedback on anorectal dynamics and sensations of pelvic floor dysfunction constipation
LUO Guo-biao;SHEN Ya-qin;YUAN Gui-ying;YANG Qi-hong;CHEN Yuan-xian
Objective
To observe the influence of electroacupuncture to double tianshu acupoints combined with biofeedback on anorectal dynamics and sensations of pelvic floor dysfunction constipation.
Methods
A total of 30 patients with moderate or above degree of pelvic floor dysfunction constipation from January 2017 to May 2018 in our hospital were selected as objects and treated by conventional therapies and electroacupuncture combined with biofeedback.The anorectal motility and sensory changes before and after treatment were compared.
Results
Anal resting pressure,maximum constrictive pressure,anal residual pressure,initial intentional sensation,sensory threshold volume after treatment were lower than those before treatment,and the differences were statistically significant(P＜0.01).
Conclusion
Electroacupuncture combined with biofeedback in the treatment of pelvic floor dysfunction constipation can improve the anorectal dynamics and sensations.
2018 Vol. 25 (30): 33-35 [
Abstract
] (
116
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36
Effect of multi-frequency vibration therapy device on preventing pulmonary infection in patients with cervical spinal cord injury
YAN Yin;GUAN Xi-hong;TONG Hua-zhang;SHAO Xiu-qin
Objective
To explore the effect of multi-frequency vibration therapy device on preventing pulmonary infection in patients with cervical spinal cord injury(CSCI).
Methods
A total of 60 patients with CSCI admitted to the First Affiliated Hospital of Nanchang University from January 2017 to March 2018 were selected as objects.They were divided into the control group and the intervention group according to the random number table method,with 30 cases in each group.In the control group,traditional sputum excretion of aerosol inhalation was used,including aerosol inhalation therapy and roll-back method,while in the intervention group,multi-frequency vibration therapy device was added on the basis of aerosol inhalation.After 7-day continuous treatment,the clinical efficacy,the incidence of pulmonary infection,and the satisfaction rate of the patients′families were compared between the two groups.
Results
The total effective rate of sputum excretion in the intervention group was significantly higher than that in the control group,with significant difference (P=0.021).The incidence of pulmonary infection in the intervention group was lower than that in the control group,with significant difference(P=0.044).The satisfaction rate of patients′families was higher than that in the control group,with statistical difference (P=0.031).
Conclusion
On the basis of traditional sputum excretion treatment,application of multi-frequency vibration therapy device for patients with CSCI can effectively clear the respiratory secretions in time,keep the respiratory tract unobstructed,prevent the occurrence of lung infection,and significantly increase the satisfaction rate of patients′families.It is a safe and effective treatment and care measure,and is worthy of further promotion and application.
2018 Vol. 25 (30): 36-38转41 [
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114
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39
Effect of obesity intervention on paroxysmal atrial fibrillation
LIU Shi-ming;ZENG Zhao-huan;JIANG Tao;QIU Xia
Objective
To study the effect of obesity intervention on patients with paroxysmal atrial fibrillation.
Methods
A total of 100 obese patients with paroxysmal atrial fibrillation admitted to our hospital from September 2016 to June 2017 were enrolled in the study,and they were divided into the control group and the observation group according to the random number table method,50 cases in each group.In the control group,previous lifestyle was used,while in the observation group,body weight management for obesity control was adopted.Both groups were followed up for 6 months.The frequency of atrial fibrillation and the incidence of stroke were compared between the two groups.
Results
The frequency of atrial fibrillation in the observation group was 8.00%,which was lower than that in the control group accounting for 32.00%,with significant difference (P＜0.05).The incidence of stroke in the observation group was 2.00%,which was lower than that in the control group accounting for 16.00%,with significant difference (P＜0.05).
Conclusion
Obesity intervention can accurately decrease the frequency of atrial fibrillation and the incidence of stroke in patients with paroxysmal atrial fibrillation,increase patients′survival rate,and reduce the economic burden of obese patients and society.
2018 Vol. 25 (30): 39-41 [
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127
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42
Clinical effect of modified abdominal puncture drainage combined with intraperitoneal injection of Torsemide and Dopamine in the treatment of cirrhosis with refractory ascites
LAI Jian-rong;YI Pei-zhuang;ZHOU Qi-ming;CHEN Yuan-hui;DUAN Xiao-ping
Objective
To investigate the clinical efficacy of modified abdominal puncture drainage combined with intraperitoneal injection of Torsemide and Dopamine in the treatment of cirrhosis and refractory ascites.
Methods
A total of 60 patients with cirrhosis and refractory ascites hospitalized in our hospital from January 2016 to December 2017 were selected as the study subjects,and they were randomly divided into the control group(30 cases)and the observation group(30 cases).The control group received routine treatment measures such as liver protection,enzyme lowering,diuretic detumescence,protein supplementation and electrolyte balance,and antiviral treatment for viral hepatitis patients.A modified central venous catheter was used for intraperitoneal indwelling drainage.In the observation group,20 mg of Dopamine Hydrochloride and 20-40 mg of Tolasemine were injected into the abdominal cavity at the same time every other day on the basis of the control group.The therapeutic effects of the two groups were compared.
Results
The total effective rate of the observation group was 90%,which was higher than 50%of the control group,and the difference was statistically significant(P＜0.05).The improvement of liver function indexes in the observation group was better than that in the control group,and the difference was statistically significant(P＜0.05).
Conclusion
Modified abdominal puncture drainage combined with intraperitoneal injection of Torsemide and Dopamine in the treatment of cirrhosis and refractory ascites can synergistically improve the clinical treatment effect,which can be further promoted and applied.
2018 Vol. 25 (30): 42-44 [
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] (
119
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45
Influence of Fuqingzhu′s Baochanwuyoufang on the duration of labor of mild cephalopelvic disproportion primipara
TONG Mei-he;YU Hai-wei;MAO Qian-guo
Objective
To investigate the influence of Fuqingzhu′s Baochanwuyoufang on the duration of labor of mild cephalopelvic disproportion primipara.
Methods
From March 2014 to September 2016,the clinical data of 254 primipara with mild cephalopelvic disproportion underwent vaginal delivery in Xiamen Hospital of Traditional Chinese Medicine Affiliated to Fujian University of Traditional Chinese Medicine were analyzed.According to whether to start taking the traditional Chinese medicine made by Fuqingzhu′s Baochanwuyoufang at the time of threatening labor,they were divided into the traditional Chinese medicine group(147 cases)and the control group(107 cases).The time of the stages of labor and the use of labor intervention measures between the two groups were analysed.
Results
In the traditional Chinese medicine group,the duration of the first stage,the second stage,the third stage and the total stage of the traditional Chinese medicine group were statisticly shorter than those of the control group,with significant difference(P＜0.05).The propotions of using oxytocin,artificial rupture of membranes and bare-handed rectifying abnormal fetal head position in the traditional Chinese medicine group were lower than those in the control group,with significant difference (P＜0.05).
Conclusion
Taking Fuqingzhu′s Baochanwuyoufang orally can accelerate cervical dilatation and the fetal descent,decrease the adoption of labour interventions,and can shorten the duration of labor.
2018 Vol. 25 (30): 45-47 [
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94
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48
Effect comparison of Low Molecular Weight Heparin Calcium with different injection methods in the treatment of venous crisis of pedicle flap
WU Yao-qiang;CHEN Ning;LAI Sheng-hua;ZHOU Li-zhi
Objective
To compare the effect of Low Molecular Weight Heparin Calcium with different injection methods in the treatment of venous crisis of pedicle flaps.
Methods
A total of 50 patients with venous crisis of pedicle flap in our hospital from February 2017 to February 2018 were randomly selected as the research objects.According to the different injection methods of Low Molecular Weight Heparin Calcium,they were divided into local subdermal injection in flap congestion area plus bloodletting with a small incision group(the flap congestion area group,n=25)and umbilical subcutaneous injection plus bloodletting with a small incision in the flap congestion area group (the umbilical group,n=25).The flap necrosis rate,activated partial thromboplastin time (APTT),and hematoma under the flap were statistically compared between the two groups.
Results
The flap necrosis rate in the flap congestion area group was significantly lower than that in the umbilical group,and the difference was statistically significant(P＜0.05).The APTT in the flap congestion area group was significantly shorter than that in the umbilical group,and the difference was statistically significant(P＜0.05).However,there was no significant difference in the incidence of subcutaneous hematoma between the two groups(P＞0.05).
Conclusion
Compared with umbilical subcutaneous injection plus bloodletting with a small incision in the flap congestion area,Low Molecular Weight Heparin Calcium with local subdermal injection in flap congestion area plus bloodletting with a small incision obtains a better effect on treating venous crisis of pedicle flap.
2018 Vol. 25 (30): 48-50 [
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98
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51
Effect comparison of thoracoscopic surgery in primary hospitals and small incision surgery under the axilla in the treatment of pulmonary bullae
LIU Zong-liang
Objective
To compare the effect of thoracoscopic surgery in primary hospitals and small incision surgery under the axilla in the treatment of pulmonary bullae.
Methods
A total of 86 cases of pulmonary bullae in the Department of General Thoracic Surgery of People′s Hospital of Linyi Economic and Technical Development District,Shandong Province,from November 2006 to November 2017 were selected as the research objects.According to the odd and even number grouping method,they were divided into the experimental group and the contrast group,43 cases in each group.The experimental group was treated with thoracoscopic surgery,and the contrast group was treated with small incision surgery under axillary fossa.The operation time,the amount of bleeding,the retention time of the chest tube,the time of hospitalization,the pain degree score (VAS)and the recrudescence of pneumothorax of the two groups were compared.
Results
The operative time of the patients in the experimental group was shorter than that in the contrast group,with significant difference (P＜0.05).The amount of intraoperative bleeding in the experimental group was less than that in the contrast group,with significant difference (P＜0.05).The retention time of the chest tube in the experimental group was shorter than that in the contrast group,with significant difference (P＜0.05).The time of hospitalization in the experimental group was shorter than that in the contrast group,the difference was statistically significant(P＜0.05).The VAS score of the experimental group was lower than that of the contrast group,with significant difference(P＜0.05).The recurrence rate of pneumothorax in the experimental group was lower than that in the contrast group,and the difference was statistically significant(P＜0.05).
Conclusion
The results of thoracoscopic surgery in primary hospitals in the treatment of pulmonary bullae are significant,and the wounds are small,which can reduce the recurrence rate.It is worthy of clinical promotion and application.
2018 Vol. 25 (30): 51-53 [
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145
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54
Clinical efficacy of modified ligation of intersphincteric fistula tract in the treatment of simple sphincter-type anal fistula
LAI Neng-sheng;LIU Zhen-hong;CHEN Zhi-lin;MAI Li-chang;CHANG Bing
Objective
To explore the clinical efficacy and safety of modified ligation of intersphincteric fistula tract(LIFT)in the treatment of simple sphincter-type anal fistula.
Methods
A total of 116 patients with simple sphinctertype anal fistula admitted to our hospital from January 2016 to January 2018 were selected as the research object,according to the random number table method,they were divided into the control group (58 cases)and the experimental group(58 cases).The control group was treated with routine LIFT,while the experimental group was treated with modified LIFT.Follow up was performed after operation.The postoperative clinical efficacy,operation time,hospital stay,postoperative pain score,and postoperative complications were compared between the two groups.
Results
The total effective rate of the experimental group was higher than that of the control group (P＜0.05),and there was no significant difference in the time of hospitalization between the two groups(P＞0.05).The operation time of the experimental group was significantly shorter than that of the control group,with significant difference(P＜0.05).The VAS score of the experimental group was significantly less than that of the control group,with significant difference(P＜0.05).The incidence of complications in the experimental group was significantly lower than that in the control group,with significant difference (P＜0.05).
Conclusion
The modified LIFT has a higher clinical efficacy in the treatment of simple sphincter-type anal fistula.It shortens the operation time,reduces postoperative pain score,improves the cure rate of patients,and reduces the incidence of postoperative complications.It is worthy of promotion.
2018 Vol. 25 (30): 54-56 [
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106
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57
Clinical effect of application of combination of Zedoary Turmeric Oil Injection and laparoscopy in the treatment of simple adhesive intestinal obstruction
LAI Da-wang;XIE Bin;DING Bang-ping
Objective
To explore the clinical effect of application of combination of Zedoary Turmeric Oil Injection and laparoscopy in the treatment of simple adhesive intestinal obstruction.
Methods
Altogether 80 cases of simple adhesiveness intestinal obstruction who were treated in our hospital from February 2015 to February 2018 were randomly selected as the object of this research and divided into the control group and the observation group according to the admission sequence numbers,with 40 cases in each group.The patients in control group were treated with laparoscopy,and the observation group was treated with Zedoary Turmeric Oil Injection on the basis of the control group.The clinical efficacy and various treatment indicators of the two groups were observed and compared.
Results
The total effective rate of the observation group was 92.50%,which was significantly higher than that of the control group(75.00%)(P＜0.05).There was no statistically significant difference in the pre-treatment scores of abdominal pain,abdominal distention and vomiting between the two groups(P＞0.05).The scores of abdominal pain,abdominal distention and vomiting were obviously improved in the two groups after 1-month treatment,and the scores of the observation group were lower than those of the control group (P＜0.05).
Conclusion
Application of combination of Zedoary Turmeric Oil Injection and laparoscopy is significantly effective in the treatment of simple adhesive intestinal obstruction,which is worthy of wider promotion.
2018 Vol. 25 (30): 57-59 [
Abstract
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92
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60
Effect of non-invasive ventilation combined with Compound Ipratropium Bromide in the treatment of chronic obstructive pulmonary disease with respiratory failure
WANG Yi
Objective
To investigate the effect of non-invasive ventilation combined with Compound Ipratropium Bromide in the treatment of respiratory failure in patients with chronic obstructive pulmonary disease(COPD).
Methods
A total of 60 patients with COPD and respiratory failure treated in our hospital from October 2015 to March 2017 were selected.They were randomly divided into the control group and the observation group,with 30 cases in each group.The control group was assisted by non-invasive ventilation on the basis of routine treatment.The patients in the observation group were added with the Compound Isoprominium Bromide on the basis of the control group,and the effect of intervention was compared between the two groups.
Results
After treatment,the PaO
2
and pH values in the observation group were higher than those in the control group (P＜0.05),and PaCO
2
was lower than that in the control group (P＜0.05).The FEV
1
and FEV
1
/FVC of the observation group after treatment were higher than those of the control group(P＜0.05).The hospitalization time and mechanical ventilation time in the observation group were shorter than those in the control group,after 7 d treatment,the heart rate of the observation group was slower than that of the control group,and the incidence of ventilator-associated pneumonia was lower than that of the control group (P＜0.05).
Conclusion
The combination of non-invasive ventilation and Compound Ipratropium Bromide for patients with COPD combined with respiratory failure can improve the index of arterial blood gas analysis and pulmonary function.It is worth promoting in clinical work.
2018 Vol. 25 (30): 60-62-69 [
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119
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63
Value analysis of intravenous pump Dexmedetomidine in gynecologic laparoscopic surgery
WU Zhen-hui
Objective
To investigate the value of intravenous pump Dexmedetomidine in gynecological laparoscopic surgery.
Methods
A total of 100 female patients undergoing gynecological laparoscopic surgery admitted to our hospital from June 2016 to September 2017 were selected as objects and they were randomly divided into test group(n=50)and control group (n=50)according to the lottery.The control group was given the routine anesthesia,and the test group was given the routine anesthesia and intravenous injection of 0.5 μg/kg Dexmedetomidine 30 min before the surgery(completed within 15 min).The scores of sedation,agitation and chill,simple mental state assessment scale(MMSE)score and complications were compared between the two groups.
Results
The scores of sedation,agitation and chill in the test group were significantly higher than those in control group,and the differences were statistically significant(P＜0.05).There was no significant difference in MMSE score before surgery between the two groups(P＞0.05).The MMSE scores after surgery in two groups were lower than those before surgery,and the differences were statistically significant(P＜0.05).The score of MMSE after surgery in the test group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The total incidence of complications in the test group was lower than that in the control group,and the difference was statistically significant(P＜0.05).
Conclusion
In gynecological laparoscopic surgery,the use of Dexmedetomidine can reduce the agitation and chill during the general anesthesia recovery period,and play a better sedative role to protect postoperative cognitive ability,which is worthy of promotion.
2018 Vol. 25 (30): 63-65 [
Abstract
] (
108
)
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66
Application effect of Dexmedetomidine on postoperative laparoscopic gastric cancer in elderly patients
ZHU Rong;CHEN Yun-liang;WANG Bo;WU Chuan;XIONG Zhao-hui
Objective
To investigate the application effect of Dexmedetomidine on postoperative laparoscopic gastric cancer in elderly patients.
Methods
From January 2016 to December 2017,a total of 80 elderly patients who underwent laparoscopic radical gastrectomy for gastric cancer were selected as objects and divided into the Dexmedetomidine group (group D)and the control group (group C)according to the random envelope method,with 40 cases in each group.Group D received Dexmedetomidine 1 μg/kg within 15 min,and then received that 0.4 μg/kg,while group C received the same volume of physiological saline.All patients were anesthetized with epidural anesthesia combined with intravenous anesthesia and received postoperative multimodal analgesia.The operation time,intraoperative fluid volume,anesthetic dose,length of hospital stay,postoperative nausea and vomiting,postoperative inflammatory response(C-reactive protein[CRP],interleukin-6[IL-6],erythrocyte sedimentation rate[ESR],neutrophil percentage[N]),and postoperative functional recovery(PQRS)(emotive domain[ED],nociceptive domain[ND],cognitive domain[CD],overall postoperative function recovery[OPR])were compared between the two groups.
Results
There were no significant differences in the operation time and intraoperative fluid volume between the two groups(P＞0.05).The doses of Propofol and Sufentanil in the group D were less than those in the group C,the hospital stay was shorter than that in the group C,the rate of postoperative nausea and vomiting was lower than that in the group C,and the differences were statistically significant(P＜0.05).There were no significant differences in CRP and N at each time point after surgery between the two groups (P＞0.05).The ESR and IL-6 levels at each time point after surgery in the group D were lower than those in the group C,and the differences were statistically significant(P＜0.05).The values of ED,ND,CD and OPR at each time point after surgery in the group D were significantly higher than those in the group C,and the differences were statistically significant(P＜0.01).
Conclusion
The application of Dexmedetomidine in elderly patients undergoing laparoscopic radical gastrectomy for gastric cancer can significantly reduce the dosage of anesthetic,shorten the hospitalization time,reduce the postoperative inflammatory response,and facilitate postoperative functional recovery.
2018 Vol. 25 (30): 66-69 [
Abstract
] (
100
)
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11
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70
Effect observation of small tidal volume and double lung ventilation on airway management in patients undergoing thoracoscopic lobectomy
LONG Yan;LIU Jun
Objective
To explore the clinical application value of small tidal volume and double lung ventilation in patients undergoing thoracoscopic lobectomy.
Methods
A total of 40 patients who underwent lobectomy from September 2016 to September 2017 in our hospital were selected as the research subjects,and they were divided into the observation group and the control group according to the random blind selection method,with 20 cases in each group.The patients in the observation group were given single lumen endotracheal intubation,and double lung ventilation was performed during the operation.The patients in the control group were given double lumen endotracheal intubation,and single lung ventilation was performed during the operation.The completion time of anesthesia intubation,operation time,recovery time,and the pulse oxygen saturation(SpO
2
)and arterial partial pressure of carbon dioxide(PaCO
2
)at 10 min after the lateral position(T
1
),1 h after the start of the operation(T
2
)and 10 min after the end of the operation(T
3
)were compared between the two groups.
Results
The completion time of anesthesia intubation in the observation group was shorter than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in operation time and recovery time between the two groups(P＞0.05).There were no significant differences in SpO
2
and PaCO
2
at each time point between the two groups (P＞0.05).
Conclusion
The operation of airway management mode with small tidal volume and double lung ventilation in patients with thoracoscopic lobectomy is simple and easy to grasp.It can avoid ventilator associated lung injury caused by single lung ventilation,which is worthy of promotion and application.
2018 Vol. 25 (30): 70-72 [
Abstract
] (
90
)
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73
Application effect of narcotrend anesthesia depth monitoring feedback adjusting Propofol by closed-loop target-controlled infusion in gynecologic laparoscopic surgery
LIN Li-tian;HUANG Fang;PENG Hui-hua
Objective
To investigate the application effect of narcotrend anesthesia depth monitoring feedback adjusting Propofol by closed-loop target-controlled infusion in gynecologic laparoscopic surgery.
Methods
One hundred and twenty patients undergoing gynecologic laparoscopic surgery from October 2016 to December 2017 in our hospital were selected as objects and divided into observation group and control group according to the different monitoring methods,with 60 cases in each group.In the observation group,anesthetic drug was provided under the narcotrend anesthesia depth monitor,while in the control group,drug was provided based on the anaesthetist′s experience.The doses of drugs,awakening time and adverse reactions between the two groups were compared.
Results
The doses of Propofol,Vecuronium,and Remifentanil in the observation group were less than those in the control group,and the differences were statistically significant(P＜0.05).The spontaneous breathing recovery time,blinking time,extubation time and orientation recovery time in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(P＜0.05).The incidence of adverse reactions such as body writhing,dizziness,nausea and vomiting in the observation group was lower than those in the control group,and the differences were statistically significant(P＜0.05).
Conclusion
The narcotrend anesthesia depth monitoring feedback adjusting Propofol by closed-loop target-controlled infusion in gynecological laparoscopic surgery can maintain the appropriate depth of anesthesia,and also can reduce the dose of anesthetic drugs with high safety,which is worthy of clinical promotion.
2018 Vol. 25 (30): 73-75 [
Abstract
] (
88
)
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76
Bibliometric analysis of research hotspots of analgesia or sedation strategy for mechanically ventilated patients based on PubMed
LI Yan
Objective
To study the analgesic and sedative literature of mechanically ventilated patients,and to analyze the current research situation of this topic in the medical field.
Methods
Based on the PubMed database,all published literatures were searched and analyzed(the search deadcine was April 5
th
,2018).The frequency of occurrence of MeSH terms was statistically analyzed.SPSS statistical software was utilized to cluster the word matrix.The statistical results showed the contemporary research hotspot of analgesia or sedation strategy for mechanically ventilated patients.
Results
There were 62 articles associated with analgesia or sedation strategy for mechanically ventilated patients,altogether 34 MeSH terms were found in the PubMed database,and 34 terms were clustered into six groups according to their cooccurrence.
Conclusion
Six hotspots are adverse reactions for radiation therapy after pneumonectomy,postoperative care of mechanically ventilated patients,pharmacology of hypnotics and sedatives,administration and dose of hypnotics and sedatives,prevention and control of pneumonia,and withholding treatment and nursing for mechanically ventilated patients.
2018 Vol. 25 (30): 76-78 [
Abstract
] (
77
)
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79
Analysis of the correlation between vulnerability of carotid artery plaque and cerebrovascular accident
LI Li-qun;WU Xi-xiang;WANG Rong
Objective
To investigate the correlation between vulnerability of carotid artery plaque (CAP)and cerebrovascular accident.
Methods
A total of 80 CAP patients treated in our hospital from September 2017 to April 2018 were selected as the subjects,and they were divided into observation group (with cerebrovascular accident)and control group(without cerebrovascular accident)by whether had cerebrovascular accident,with 40 cases in each group.All the patients were examined by color ultrasound,the acoustic imaging features of plaque were analyzed.The vulnerability of CAP and stable plaque were compared between the two groups.The correlation between vulnerable plaque and cerebrovascular accident was analyzed.
Results
According to color ultrasound,49 plaques were detected in control group and 63 plaques were detected in observation group.The rate of ulcerous plaque and soft plaque in observation group was higher than that in control group,the rate of wide hard plaque and flat plaque in observation group was lower than control group,the difference was statistically significant(P＜0.05).The rate of stable plaque in observation group was lower than that in control group,while the rate of vulnerable plaque in observation group was higher than control group,the difference was statistically significant(P＜0.05).According to Pearson analysis,the vulnerable plaque had positive correlation with cerebrovascular accident(r=0.295,P＜0.05).
Conclusion
The incidence of cerebrovascular accident has positive correlation with vulnerability of CAP.Color ultrasound can judge the vulnerability of CAP,so as to predict the risks of cerebrovascular accidents.
2018 Vol. 25 (30): 79-81 [
Abstract
] (
87
)
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13
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82
Application value of four-dimensional color Doppler ultrasound in diagnosis of fetal malformation and intellectual development disorders
WU Gong-lili;ZENG Guang-yuan;XU Qiao-ya;WU Yan
Objective
To study the application value of four-dimensional color Doppler ultrasound in diagnosis of fetal malformation and intellectual development disorders.
Methods
A total of 32 pregnant women who undergo prenatal care from December 2015 to February 2018 in our hospital were selected.All patients were confirmed by pathological examination.According to different methods of diagnosis,they were divided into study group and reference group.The reference group used two dimensional color Doppler ultrasonography.The study group used four-dimensional color Doppler ultrasound.The results of fetal malformation and detection results of nuchal translucency thickness.
Results
The diagnostic accuracy of fetal malformation in the study group was 90.63%,which was higher than that of the reference group (65.63%),and the difference was statistically significant(P＜0.05).Of 32 pregnant women,there were 5 cases with abnormal nuchal translucency thickness,the detection rate of intellectual developmental abnormalities was 100.00%,which was higher than the detection rate of mental developmental abnormalities in 27 cases normal nuchal translucency thickness(7.41%),and the difference was statistically significant(P＜0.05).
Conclusion
The use of fourdimensional color Doppler ultrasound diagnostic technology has significant application value in the diagnosis of fetal malformation and fetal mental development.It is worthy of promotion.
2018 Vol. 25 (30): 82-84 [
Abstract
] (
80
)
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22
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85
Clinical value of 1.5T magnetic resonance imaging in the diagnosis of knee degenerative osteoarthrosis
YE Jia-run
Objective
To investigate the diagnostic value of 1.5T magnetic resonance imaging(MRI)in knee degenerative osteoarthrosis.
Methods
A retrospective analysis of 65 patients with suspected knee degenerative osteoarthrosis treated in our hospital from January 2017 to March 2018 was performed.All patients underwent 1.5T MRI,and the results of arthroscopic surgery were set as a golden standard.The examination results and diagnostic efficacy of 1.5T MRI were explored.
Results
Of the 65 patients with suspected knee degenerative osteoarthrosis,47 patients were positive on MRI,and 18 were negative.Among them,the knee stenosis of joint cavity,the formation of osteophyte at the edge of the joint and the detection rate of free body in the joint cavity were the highest,all accounting for 17.02%.The 65 patients were all definitely diagnosed by surgical pathology,including 45 patients with knee degenerative osteoarthrosis.MRI examinations of 59 patients were consistent with the results of surgical pathology.The diagnostic sensitivity,specificity,and accuracy was 91.49%,88.89%,and 90.77%respectively.
Conclusion
1.5T MRI can provide reliable reference information for the diagnosis of knee joint degenerative osteoarthrosis,and has high clinical value.
2018 Vol. 25 (30): 85-87 [
Abstract
] (
73
)
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11
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88
Application value of multi-slice spiral CT in a low-dose scanning technique in the diagnosis of rib fractures
TANG Hui;QI Kun-sheng
Objective
To analyze the application value of multi-slice spiral CT in a low-dose scanning technique in the diagnosis of rib fractures.
Methods
A total of 50 patients with rib fractures who were diagnosed at our hospital from February 1st,2017 to February 1st,2018 were selected as the subjects.All patients underwent multi-slice spiral CT in a low-dose scanning and chest digital X-ray radiography were performed.The image quality and diagnostic accuracy obtained by the two inspection methods were compared.
Results
There was no statistic difference in image quality scores of the whole lung,upper lung,middle lung and lower lung obtained by low-dose multi-slice spiral CT and by chest digital X-ray radiography technique (P＞0.05).The diagnostic accuracy of low-dose multi-slice spiral CT(96.00%)was higher than that of chest digital X-ray radiography technique (70.00%),the difference was statistically significant(P＜0.05).
Conclusion
The multi-slice spiral CT in a low-dose scanning technique for rib fractures has high accuracy.
2018 Vol. 25 (30): 88-90 [
Abstract
] (
80
)
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15
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91
Application value of ultrasound in the diagnosis of thyroid occupying lesions
DENG Li
Objective
To investigate the value of ultrasonography in the diagnosis of thyroid space occupying lesions.
Methods
A total of 234 cases of thyroid occupying lesions treated in our hospital from Junuary to December in 2017 were selected as the subjects.All the patients received color Doppler ultrasound and pathological diagnosis to evaluate the value of ultrasound diagnosis.
Results
Pathological examination showed that all the 234 cases were diagnosed as thyroid occupying lesion,and 234 cases were detected by ultrasound.The benign nodules were characterized by longitudinal and transverse ratio of＜1,echo,mixed echo,morphologic rule,and boundary clear.The malignant nodules were hypoechoic,extremely low echo,vertical and horizontal ratio＞1,irregular shape,blurred boundary,and lobulated edge.The sensitivity,specificity and accuracy of ultrasound diagnosis were 73.58%,92.27%and 88.03%respectively.Conclusion Ultrasonography has high accuracy in diagnosing thyroid space occupying lesions,and has obvious advantages in differentiating benign from malignant lesions.
2018 Vol. 25 (30): 91-93 [
Abstract
] (
67
)
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17
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94
Clinical value of high frequency ultrasound in diagnosis of mesenteric lymphadenitis in children
LAI Gan-ping
Objective
To analyze the clinical value of high frequency ultrasound in diagnosis of mesenteric lymphadenitis in children.
Methods
Altogether 52 children with mesenteric lymphadenitis who were examined in our hospital from January 2016 to June 2018 were selected as the study group,and 52 children who underwent health examination at the same time were selected as the control group.The coincidence rate of high-frequency ultrasound diagnosis was evaluated according to the results of pathological examination.The size of lymph nodes was compared between the two groups and the imaging findings of lymph nodes was analyzed.
Results
The coincidence rate of high-frequency ultrasonography in diagnosis of mesenteric lymphadenitis was 96.15%,and there was no statistically significant difference in comparison with pathological diagnosis results(P＞0.05).The transverse and longitudinal diameters of mesenteric lymph nodes of the study group were larger than those in the control group,with statistically significant difference(P＜0.05).The lymph nodes were centrally distributed in the right lower abdomen or umbilical cord(there were 27 cases of right lower abdominal lymph node enlargement,5 cases of left umbilical lymph node enlargement and 20 cases of periumbilical lymph node enlargement),with ellipse shape,regular morphology,clear margin,structurally-complete capsule and lymphatic hilum as well as scattered and non-fused enlarged lymph nodes.The post-treatment transverse diameter and longitudinal diameter of lymph nodes of study group were smaller than those before treatment and the aspect ratio was greater than that before treatment,with statistically significant difference (P＜0.05).
Conclusion
Highfrequency ultrasound has the high accuracy and easy-to-operate features in diagnosis of mesenteric lymphadenitis in children,through which doctors can analyze the imaging characteristics of nodules to determine the disease,and then provide a reference for follow-up diagnosis and treatment.
2018 Vol. 25 (30): 94-96 [
Abstract
] (
77
)
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97
Effect of Breviscapine Injection combined with Monosialicganglioside on peripheral facial paralysis
LIU Bing-shi;ZHONG Wen-juan;LIN Jian-qun
Objective
To explore the effect of Breviscapine Injection combined with Monosialicganglioside on peripheral facial paralysis.
Methods
Ninety patients with peripheral facial paralysis admitted to our hospital from January 2015 to December 2017 were randomly divided into control group (n=45)and observation group (n=45),the observation group was given routine treatment+Breviscapine Injection combined with Monosialoganglioside treatment,while the control group was given routine treatment.The clinical efficacy and related indicators of the two groups were compared.
Results
The total effective rate of the observation group was significantly higher than that of the control group (P＜0.05).There was no significant difference in Portmann score between the two groups before treatment(P＞0.05),the Portmann score of the observation group at 7 d and 2 weeks after treatment were significantly higher than that before treatment,and significantly higher than that of the control group,the differences were statistically significant(P＜0.05).There was no significant difference in the amplitude and latency of facial nerve between the two groups before treatment(P＞0.05).After treatment,the amplitude of facial nerve wave in observation group was significantly higher than that before treatment,and the latency of facial nerve was significantly shorter than that before treatment,the differences were statitically signifscant(P＜0.05).After treatment,the amplitude of facial nerve wave in the observation group was significantly higher than that in the control group,and the latency of facial nerve was significantly shorter than that in the control group,the differences were statitically signifscant(P＜0.05).
Conclusion
Patients with peripheral facial paralysis were treated with Breviscapine Injection combined with Monosialoganglioside,the curative effect is definite and it has clinical value.
2018 Vol. 25 (30): 97-99-103 [
Abstract
] (
90
)
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14
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100
Effect of Shenfu Injection combined with Recombinant Human Brain Natriuretic Peptide on acute heart failure
LIN Jin-mei;ZHENG Shi-zhen;ZHENG Qiao-ling;ZHENG Fang
Objective
To explore the effect of Shenfu Injection combined with Recombinant Human Brain Natriuretic Peptide in the treatment of acute heart failure.
Methods
A total of 82 patients with acute heart failure (AHF)admitted to our hospital from December 2015 to November 2017 were randomly divided into study group and control group,41 cases in each group.Two groups of patients were given AHF routine treatment,on this basis,the control group was given Recombinant Human Brain Natriuretic Peptide (rhBNP)treatment,the study group was given Shenfu Injection and rhBNP combined treatment.The levels of cardiac function and serum neurohormonal factors were compared between the two groups before and after treatment.
Results
Left ventricular ejection fraction (LVEF)and left ventricular short axis shortening rate (FS)were significantly higher after treatment in both groups than before treatment,and left ventricular end diastolic diameter(LVIDd)was significantly lower than before treatment,after treatment,LVEF and FS in the study group were significantly higher than those in the control group,and LVIDd was significantly lower than that in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of N-terminal B type natriuretic peptide precursor(NT-proBNP),noradrenaline(NE)and endothelin 1(ET-1)in the two groups were significantly lower than those before treatment,NT-proBNP,NE and ET-1 in the study group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).The standard deviation of RR interval(SDNN),the standard deviation of 5 min mean(SDANN),the square root of adjacent RR interval(RMSSD),low frequency power(LF)and high frequency power(HF)were significantly higher in both groups than before treatment,after treatment,the values of square,SDANN,RMSSD,LF and HF in the study group were significantly higher than those in the control group,the differences were statistically significant(P<0.05).
Conclusion
The clinical effect of Shenfu Injection combined with rhBNP in the treatment of AHF is remarkable.It can significantly improve the serum levels of NT-proBNP,NE,ET-1,and is worthy of clinical application.
2018 Vol. 25 (30): 100-103 [
Abstract
] (
79
)
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9
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104
Effect of N-Acetylcysteine combined with low-dose of Azithromycin on airway mucus hypersecretion in stable phase of chronic obstructive pulmonary disease
LI Fa-gen;CHEN Xian-xiang
Objective
To investigate the effect of N-acetylcysteine combined with low-dose Azithromycin on airway mucus hypersecretion in stable phase of chronic obstructive pulmonary disease (COPD).
Methods
Eighty-four patients with stable COPD treated in our hospital from January 2016 to October 2017 were selected as observation objects,they were divided into control group and intervention group according to random number table method,with 42 cases in each group.The control group received routine treatment,and the intervention group received N-acetylcysteine and Azithromycin on the basis of the control group,after 6 months of continuous treatment,the lung function,activity endurance and serum inflammatory factors were compared between the two groups.
Results
There was no significant difference between the two groups in the first second forced expiratory volume(FEV
1
),forced vital capacity(FVC)and FEV
1
/FVC (P＞0.05);After treatment,the 6-minute walking distance (6-MWD)of intervention group was longer than that of control group,the differences were statistically significant(P＜0.05).The levels of serum inflammatory factors,neutrophil elastase(NE),interleukin-8(IL-8)and interleukin-10(IL-10)in the two groups after treatment were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,the levels of serum inflammatory factors NE,IL-8 and IL-10 in intervention group were lower than those in control group,the differences were statistically significant (P＜0.05).
Conclusion
N-acetylcysteine combined with low-dose Azithromycin in the treatment of stable COPD effect is significant,can improve activity endurance,reduce inflammation,reduce airway mucus secretion,delay the decline of pulmonary function,worthy of clinical promotion.
2018 Vol. 25 (30): 104-106 [
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] (
111
)
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107
Clinical efficacy of Paclitaxel combined with Cisplatin in the treatment of advanced esophageal cancer
ZHAO Jian-yang
Objective
To investigate the clinical effect of Paclitaxel combined with Cisplatin in the treatment of advanced esophageal cancer.
Methods
Fifty-six patients with advanced esophageal cancer admitted to our hospital from January 2015 to November 2017 were divided into control group(n=28)and observation group(n=28)according to random number table method，the patients in the control group were given conventional treatment,while the observation group was treated with Paclitaxel conbined with Cisplatin,the total effective rate,mean survival time,tumor progression time,quality of life and the total incidence of adverse reactions were compared of patients between the two groups.
Results
The total effective rate in the observation group of patients was higher than that of the control group,the difference was statistically significant(P＜0.05).The mean survival time and tumor progression time in the observation group of patients were longer than those of the control group,the differences were statistically significant(P＜0.05).The score of quality of life in the observation group of patients was higher than that in the control group，the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups of patients(P＞0.05).
Conclusion
In the clinical treatment of advanced esophageal cancer,the combination of Paclitaxel and Cisplatin can not only improve the total effective rate,prolong the average survival time and tumor progression time,but also improve the quality of life of patients.It is worthy of promotion in clinical application.
2018 Vol. 25 (30): 107-109 [
Abstract
] (
77
)
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12
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110
Clinical observation on chronic glomerulonephritis treated by Shenyan kangfu Tablets combined with Valsartan
WU Bin-xuan;HUANG Liu-ying;LIU Shao-jie
Objective
To explore the clinical effect of Shenyankangfu Tablets combined with Valsartan in the treatment of chronic glomerulonephritis.
Methods
Ninety patients with chronic glomerulonephritis admitted to Ningde Hospital of Traditional Chinese Medicine from October 1,2015 to February 10,2016 were selected as the study subjects,the patients were divided into observation group and control group according to computer random grouping method,with 45 cases in each group,the patients in the observation group were treated with Shenyankangfu Tablets combined with Valsartan,while the control group was given conventional treatment.The glomerular filtration rate,serum potassium level,serum creatinine level,total effective rate,hospitalization time and symptom improvement time were compared between the two groups.
Results
After treatment,the glomerular filtration rate and serum potassium level of the observation group were higher than those of the control group,and the serum creatinine level was lower than that of the control group,the differences were statistically significant(P＜0.05).The total effective rate of the observation group was 95.56%,which was higher than that of the control group of 71.11%,the difference was statistically significant(P＜0.05).The hospitalization time and symptom improvement time of the observation group were shorter than those of the control group,the differences were statistically significant(P＜0.05).
Conclusion
Through the treatment of chronic glomerulonephritis patients with Shenyankangfu Tablets combined with Valsartan,achieved significant results,can improve the patient's indicators,shorten hospital stay,and promote the rehabilitation of patients.
2018 Vol. 25 (30): 110-112 [
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80
)
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6
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113
Analysis of 103 cases with adverse reaction of antibacterials in our hospital
SUN Pan-pan
Objective
To analyze the characteristics and regularity of adverse drug reactions(ADR)caused by antibiotics,reduce the incidence of ADR and promote rational clinical use of drugs.
Methods
A total of 103 cases of ADR caused by antibiotics in our hospital from January 2015 to December 2017 were collected,the basic information of the patients(sex and age),the types of antibiotics involved,the route of administration and the main clinical manifestations were analyzed.
Results
Among 103 cases of ADR caused by antibiotics,there were more males(61.17%)than females(38.83%).Elderly patients over the age of 61 years old were more common (40.78%).There were 8 types and 18 varieties of antibiotics involved,among which cephalosporins ranked first(32.04%)and followed by quinolones(24.27%).The incidence of ADR was highest(94.17%)by intravenous infusion(94.17%).It mainly involves skin and its appendages.,the main clinical manifestations are rash,papules,pruritus,flushing,etc.
Conclusion
ADR caused by antibiotics is related to many reasons.Medical staff should pay attention to and regulate the behavior of clinical medication,rational use of drugs,and ensure the safety of patients with medication.
2018 Vol. 25 (30): 113-115 [
Abstract
] (
65
)
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16
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116
Application value of combined detection of serum amyloid protein A and C-reactive protein in differential diagnosis of infective diseases in children
LU Ju-wen;WEN Cheng-bo;LIU Qiong-zhang;CHEN Jian-fa;LI fang-fang
Objective
To investigate the application value of combined detection of serum amyloid protein A(SAA)and C-reactive protein(CRP)in the differential diagnosis of infective diseases in children.
Methods
A total of 153 children with infectious diseases from August 2016 to March 2018 in our hospital were selected as the research object.According to the results of pathogen detection,they were divided into the bacterial infection group(n=81)and the virus infection group (n=72).A total of 32 healthy children in the same period were selected as the healthy control group.The levels of SAA and CRP in children in each group were detected by immunoturbidimetric method and compared.The sensitivity and specificity of SAA and CRP combined detection in the diagnosis of bacterial infectious diseases in children were analyzed.
Results
The levels of SAA and CRP in the bacterial infection group were significantly higher than those in the viral infection group and the healthy control group (P＜0.05).The level of SAA in the viral infection group was significantly higher than that in the healthy control group (P＜0.05),but there was no significant difference in the CRP level between the viral infection group and the healthy control group (P＞0.05).The ROC curve analysis showed that the area of AUC of SAA and CRP combined detection was the highest among the three diagnostic methods,and the sensitivity and specificity of the combined diagnosis of SAA and CRP were higher than that of SAA and CRP alone.
Conclusion
The combined detection of SAA and CRP can effectively distinguish the kinds of infective diseases in children,and the specificity and sensitivity of diagnosis are both high,which has high clinical application value.
2018 Vol. 25 (30): 116-118 [
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] (
78
)
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119
Application value of procalcitonin,C-reactive protein and blood glucose detection in the diagnosis of children with hand-foot-and-mouth diseases
LIANG Yu
Objective
To investigate the application value of procalcitonin,C-reactive protein and blood glucose detection in the diagnosis of children with hand-foot-and-mouth diseases (HFMD).
Methods
A total of 80 HFMD children from March 2016 to October 2017 treated in our hospital were selected as the study group.They were divided into the study group Ι(n=40)and the study group Ⅱ (n=40)according to different disease conditions.Children in study group Ι were at acute stages,while in study groupⅡ,participants were in the recovery period.At the same time,40 healthy children were selected as the control group.An automatic biochemical analyzer AU640 and matching reagents were used in HFMD children and healthy children for C-reactive protein and blood glucose detection.The procalcitonin was detected by double-antibody sandwich and chemiluminescence analysis.The differences in procalcitonin,C-reactive protein,and blood glucose were compared between the two groups.
Results
The levels of procalcitonin,C-reactive protein and blood glucose in the study group Ι were higher than those in the study group Ⅱ and the control group,with significant difference (P＜0.05).The levels of procalcitonin,C-reactive protein,and blood glucose were lower in the control group compared with those in the study groups Ι and the study group Ⅱ,with significant difference(P＜0.05).In the study group(n=80),positivity detection of procalcitonin was in 25 patients,of C-reactive protein was in 32 patients,of blood glucose was in 26 patients,and of combined detection in 65 potients.In the control group (n=40),positivity detection of procalcitonin was in 2 participants,of C-reactive protein was in 4 participants,of blood glucose was in 3 participants,and of combined detection in 6 participants.The sensitivity and specificity of combined diagnosis were higher than those of single diagnosis,with statistical significance(P＜0.05).
Conclusion
The positivity rate of procalcitonin,C-reactive protein and blood glucose in children with HFMD is high.Joint application of these three tests can effectively improve the diagnostic sensitivity of children with HFMD and provide reliable diagnostic basis for clinical treatment.
2018 Vol. 25 (30): 119-121 [
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72
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122
The value of blood detection in the diagnosis and differential diagnosis of anemia
TAN Hua
Objective
To explore the value of blood detection in the diagnosis and differential diagnosis of anemia.
Methods
A total of 80 patients with anemia admitted in our hospital from October 2014 to October 2017 were selected as the subjects.According to the types of anemia,all the anaemic patients were divided into the thalassemia group (n=40)and tha iron deficiency anemia group (n=40).Meanwhile,40 healthy persons who came to the hospital in the same period were selected as the healthy control group.The blood cells of the three groups were measured,and the red blood cell count(RBC),the mean hemoglobin (MCH),the hemoglobin (Hb),the volume distribution width of red blood cell(RDW),the mean volume of red blood cell(MCV)and the ratio of RBC/MCV were analyzed.
Results
the MCV and MCH indexes of patients with the thalassemia group and the iron deficiency anemia group were significantly lower than those in the healthy control group,and the difference was statistically significant(P＜0.05).The RBC/MCV and RBC indexes of the thalassemia group were significantly higher than those in the iron deficiency anemia group and the healthy control group,and the difference was statistically significant(P＜0.05).The RDW indexes of the patients in the iron deficiency anemia group were significantly higher than those in the thalassemia group and the healthy control group,and the RBC and Hb indexes in the iron deficiency anemia group were significantly lower than those of the other two groups,and the difference was statistically significant(P＜0.05).
Conclusion
Detection of MCH,RDW,MCV and RBC/MCV ratio in blood of anemia patients is of great value in the diagnosis and differentiation of anemia.
2018 Vol. 25 (30): 122-124 [
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71
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125
Clinical value of biochemical detection index in the diagnosis of acute pancreatitis
XU Nan
Objective
To investigate the clinical value of biochemical indexes such as U-Amy,S-Amy,LPS,TAP and CRP in the diagnosis of acute pancreatitis(AP).
Methods
A total of 196 patients with pancreatitis admitted in our hospital from April 2015 to April 2017 were divided into the AP group(n=91)and the non-AP group(n=105)according to clinical diagnosis.Among them,the AP group was subdivided into the mild AP group (MAP,n=57)and the severe AP group (SAP,n=34).Another 40 healthy people at the same time were selected as the healthy control group.The biochemical indexes such as U-Amy,S-Amy,LPS,TAP and CRP were measured and analyzed in the each group respectively.
Results
The level of U-Amy,S-Amy and TAP in the healthy control group,the non-AP group and the AP group increased from low to high (P＜0.05).The level of LPS in the AP group was significantly higher than that in the non-AP group and the healthy control group (P＜0.05).The levels of CRP in the AP group and the non-AP group were significantly higher than those in the healthy control group (P＜0.05).The level of U-Amy,TAP and CRP in the SAP group were significantly higher than those in the MAP group (P＜0.05),while the differences in the S-Amy and LPS level between the two groups were not significant(P＞0.05).In the diagnosis of early AP,the sensitivity and specificity of serum LPS detection were 92.3%and 91.4%,respectively,which were significantly higher than those of the other four indexes.
Conclusion
The indexes of U-Amy,S-Amy,LPS,TAP and CRP are good biochemical indexes for the diagnosis of AP.LPS can improve the accuracy of early diagnosis,while TAP and CRP help to judge the severity of the lesion and evaluate the therapeutic effect and prognosis.
2018 Vol. 25 (30): 125-127 [
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87
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128
Applying post analysis and evaluation to realize the pareto optimality analysis in the management department of public hospitals
HAO Su-juan
The rationalization and scientific establishment of management position is of great significance to improve the modern management level of public hospitals.In order to optimize the position allocation of functional logistics department,and improve the management level of post efficiency,using post analysis and post evaluation to conduct performance management for different job sequences.The pareto optimality is realized in the management department,improving the management efficiency of the post,and realizing the management effect of"the best of people".
2018 Vol. 25 (30): 128-131 [
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62
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132
Analysis of the nursing management review results of the third-cycle tertiary general hospital in Jiangxi province
GUAN Xi-hong;ZHOU Wen-yun;LIANG Bin;LIU LIN1YU Mao-lin;ZHOU Ye-lin;XIONG Chang-hui;DONG Yong-hai
In order to deepen the reform of the medical and health system,strengthen supervision and management of hospitals,promoting hospitals to strengthen the connotation construction,improving management level and service efficiency,continuously improve the quality of medical services,and ensuring medical safety,Jiangxi Provincial Health Department launched a new round of hospital review work in February 2012.Through the establishment of a hospital review organization,review normative documents and medical institutions planning,the improvement of the evaluation of expert teams,the implementation of evaluation-related training,comprehensive promotion and cultivation of a typical combination of a series of measures,the 26 three-level comprehensive hospitals carried out the hospital review work in 2017.The review included 52 nursing review terms.As a result,of the 26 hospitals,2 of the 3rd grade B passed the review and became the third grade A,and the remaining 24 hospitals remained unchanged.The proportion of “A”excellent clauses is 27.96%,the proportion of “B” good clauses is 50.8%,the proportion of “C” qualified clauses is 19.17%,the proportion of “D” unqualified clauses is 2.08%;the satisfaction of social evaluation is (95.83±2.55)%.Through a new round of hospital review,the work process was further standardized,the rules and regulations were improved,the quality of care was continuously improved,the satisfaction of social evaluation was improved,and the nursing management ability and service ability were greatly improved.
2018 Vol. 25 (30): 132-135 [
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91
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136
Clinical pharmacists′pharmacy practice in intensive care unit
QIU Yan-long SUN Fu-dong
In combination with the practice of clinical pharmacists in the intensive care unit(ICU),the entry point for clinical pharmacists to conduct pharmacy services in the ICU is discussed.Pharmacological services are provided through the participation of clinical pharmacists in the drug treatment of neurological diseases,cardiovascular diseases and multidrug-resistant infections and in guiding the rational use of drugs by nurses.Clinical pharmacist-assisted medical care involves drug selection,drug interactions,drug dosages,frequency adjustments,drug stability,etc.And their pharmaceutical advice were adopted.Clinical pharmacists participate in drug treatment of ICU patients and play important roles in promoting the safe use of drugs in critical patients.
2018 Vol. 25 (30): 136-138 [
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78
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139
Application research of mind mapping in the teaching of Health assessment for nursing students in higher vocational colleges
HUANG Xiao-li;YANG Yu-qin;ZHOU Xiao-Feng;YE Xi-Yong;LIU Yuan-Ji
Objective
To study the application effect of mind mapping in the teaching of Health assessment for nursing students in higher vocational colleges.
Methods
A total of 121 nursing students grade 2015 in higher vocational colleges of our school were selected as the study objects.They were divided into the control group (57 cases)and educational reform group (64 cases)according to the comparative study.The control group was given the traditional teaching method,while the educational reform group was given the mind maping teaching mode.The examination results between the two groups were compared,and the teaching effect of mind maping teaching mode was investigated.
Results
The results of theoretical and practical examination in the educational reform group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The survey showed that most of the students in the educational reform group thought that mind maping teaching model was conducive to enhancing learning interest,cultivating divergent thinking,helping to understand memory,helping to integrate knowledge and improving learning efficiency,and they were willing to accept mind maping teaching model for classroom learning.
Conclusion
The effect and quality of mind maping in the teaching of Health assessment for nursing students in higher vocational colleges are better than those of the traditional teaching method.It has good popularization value and practical significance.
2018 Vol. 25 (30): 139-141 [
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91
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142
A qualitative research on professional identification of students majoring in health management
ZHANG Yu-hong;DONG Fang;DAI Cui-ping
Objective
To understand the real feelings about professional identification of health management major students in order to provide reference basis for educators and supervisors majoring in health management.
Methods
A phenomenological approach in qualitative research was adopted to in-depth interviewed for 16 students majoring in health management grade 2015 and 2016.Content analysis method was used for data analysis.
Results
Optimistic job prospects,catering to interests and demands were the main reasons for choosing a health management major.Abundant knowledge and skills of health management,optimistic job prospects,and be conducive to self-health management were the positive influence factors influencing professional identification;learning was extensive but not specialized is negative factors.
Conclusion
Health management students have a higher professional identity,and the personnel training program needs to be further improved,and provide more practice and training platform for students.
2018 Vol. 25 (30): 142-144 [
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69
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145
Report of pulmonary benign metastatic leiomyoma in 1 case and literature review
PAN Ru;YANG Hai-kun;LIU Hao-chang;ZENG Wei-hong;HUANG Li-shan
Benign metastasizing leiomyoma (BML)is a rare benign disease with a slowly grown pattern.The condition typically affects women of reproductive age with a history of uterine leiomyoma,and the lung is the main site of metastasis.The clinical and pathological data of 1 patient with pulmonary benign metastatic leiomyoma(PBML)were analyzed.The chest computed tomography(CT)scan revealed multiple well-defined nodules with clear boundaries located in both lungs.A biopsy of the uterine neoplasm suggested that a cellular leiomyoma of the uterus.Pulmonary nodule biopsy revealed smooth muscle cell hyperplasia,lung nodule morphology is similar to uterine tumors,immunohistochemistry suggested that it originated from smooth muscle cells,and it was consistent with the diagnosis of PBML.Estrogen and progesterone receptors were detected in uterine leiomyoma and lung nodules.After 15 months of follow-up,no recurrence is found.The clinical manifestations of PBML are lack of specificity.Surgical resection is the main treatment.Tumors are hormone dependent and can be treated with endocrine therapy.
2018 Vol. 25 (30): 145-147-163 [
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71
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148
One case of children Behcet disease treated by immunity interfere and literature review
LIU Wen-dong;QU Bao-ming;JIAO Yan;LI Hong
The incidence of Behcet disease in children is lower than that of adults,but Behcet disease can lead to multiple system and multiple organ injuries,resulting in high disability and mortality rate,and seriously endangering children′s health．This study retrospectively analyzed the clinical data of 1 case of Behcet disease and related literature to explore the clinical features,diagnosis,treatment and prognosis of Behcet disease in children.The clinical manifestations of the disease are more typical,diagnosis should be detailed inquiry history,pay attention to differential diagnosis,so as to avoid missed diagnosis and misdiagnosis,and need long-term follow-up.
2018 Vol. 25 (30): 148-150 [
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80
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151
Application effect of transitional care on preventing falls of stroke patients discharged from hospital
LIU Hui-juan;SHENG Chuan-ling;ZHANG Xiu-yin
Objective
To investigate the application effect of transitional care on fall prevention in stroke patients discharged from hospital.
Methods
A total of one hundred stroke patients treated in our hospital from January to October 2017 were selected in this study and they were divided into control group and observation group according to random number table method,50 cases in each group.The control group was given conventional discharge instructions,and followed up by telephone visit after one week.Besides routine discharge guidance,the observation group was established personal record and observation tables,followed up by closely transitional care and intervention.Two groups were assessed for functional recovery by Functional Independence Measure(FIM)table,and the incidence of falls within six months after discharge was compared.
Results
The score of FIM in the observation group was significantly higher than control group,and the fall incidence was significantly lower than control group,the differences were statistically significant(P＜0.05）.
Conclusion
Transitional care is beneficial to the recovery of daily activity of stroke patients,and can effectively prevent the incidence of falls after discharged from hospital.
2018 Vol. 25 (30): 151-153 [
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71
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154
Effect of quality nursing intervention in operating room on anxiety and depression and postoperative pain in patients with polycystic ovary syndrome after laparoscopic surgery
YE Jian-mei;YE Jian-zhen
Objective
To explore the effect of high quality nursing intervention on anxiety and depression and postoperative pain in patients with polycystic ovary syndrome(PCOS)after laparoscopic surgery.
Methods
From December 2015 to November 2017,68 patients with PCOS underwent laparoscopic surgery in Leping City TCM Hospital of Jiangxi Province were randomly divided into study group and control group,34 cases in each group.The control group was given routine operating room nursing,and the study group was given quality nursing intervention in operation room based on the control group.Anxiety and depression before and after operation and postoperative pain were compared between the two groups.
Results
There was no significant difference in SAS scores between the two groups on the 1st day before operation (P＞0.05）;On the 7th day after operation,the scores of SAS in the study group were significantly lower than before operation(P<0.05）,and the scores in the study group were significantly lower than those in the control group (P<0.05）.The rate of severe pain in the study group was significantly lower than that in the control group 24 hours after operation (P<0.05）.The rate of moderate and mild pain was significantly higher than that of the control group(P<0.05）.The rate of severe and moderate pain in the study group was significantly lower than that in the control group at 72 hours after operation,and the rate of mild pain and painless was significantly higher than that in the control group,the differences were statistically significant(P<0.05）.
Conclusion
The application of high quality nursing intervention in operating room in the laparoscopic surgery of polycystic ovary syndrome is very effective.It can significantly improve the anxiety,depression and postoperative pain in patients with PCOS.It is worthy of clinical application.
2018 Vol. 25 (30): 154-156 [
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63
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Clinical nursing effect of subcutaneous vein finder to nocturnal prehospital first aid
ZHONG Fang-yu;CHEN Yi-wen;WANG An-hong;DENG Xiu-ji;CHEN Dong-mei;QI Xiao-min
Objective
To investigate the effect of using a subcutaneous vein finder in prehospital first aid at night.
Methods
From February 2017 to June 2018,200 pre-hospital emergency patients from the Cangzhou Medical Emergency Center were selected as the study subjects.They were divided into the control group and the experimental group by closed envelope method,and 100 patients in each group.During the rescue process,the venous puncture was performed at night using conventional general illumination.The experimental group was treated with a vein finder to perform venipuncture at night,and the number of successful punctures,second punctures,three or more punctures in the two groups and the success rate was evaluated for clinical efficacy and safety.
Results
The success rate of one puncture in the experimental group was higher than that in the control group (P<0.05）.The probability of complications such as solid catheter occlusion,fluid leakage,phlebitis,and infusion of hypertonic fluid pain in the experimental group was 4.0%.Compared with the control group,it was lower than 13.0%,the differences were statistically significant(P<0.05）.
Conclusion
In the pre-hospital emergency treatment process at night,the subcutaneous vein finder can effectively improve the success rate of the nursing staff to establish venous access for the patient,which is reliable,simple and safe.Clinically easy to promote treatment,recommended promotion.
2018 Vol. 25 (30): 157-159 [
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91
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The influence of psychological intervention on family burden and mental health of relatives of patient with cancer chemotherapy
WANG Xue-qu;DENG Lan;PENG Guo-lin;YUAN Shui-ping;ZENG Li-yun;NI Jian-mao
Objective
To study the influence of psychological intervention on family burden and mental health of relatives of patients with cancer chemotherapy.
Methods
A total of 81 cases of cancer chemotherapy treated in the 184
th
Hospital of PLA from September 2016 to August 2017 were selected for the study.These patients were divided into the control group(n=40)and the treatment group(n=41)according to the random number table method.The patients in the control group were treated with routine care,and the treatment group were conducted psychological intervention on the basis of the control group.The mental health,social support and family burden of the families of the two groups were compared.
Results
Before treatment,there was no statistically significant difference between the two groups of SDS and SAS scores (P＞0.05）.After treatment,both SDS and SAS scores in the treatment group were lower than the control group,and the differences were statistically significant(P<0.05）The SDS scores of patients in the control group before and after treatment showed no statistically significant difference (P＞0.05）.The SAS scores after treatment were higher than those before treatment,and the difference was statistically significant(P<0.05）.The SDS and SAS scores of patients in the treatment group were lower than those before treatment,and the differences were statistically significant(P<0.05）.Before treatment,the scores of daily activities,financial burden,recreational activities,external relations,members′mental health and members′physical health in the two groups were compared without statistical significance (P ＞0.05）.After treatment,the treatment group′s daily activities,the economic burden,entertainment activities,foreign relations,members,members of the health of various grades of mental health were lower than the control group,the differences were statistically significant(P＜0.05）.The scores of the control group before and after treatment were not statistically significant(P＞0.05）,and the scores of the treatment group were lower than before treatment,with statistically significant difference(P＜0.05）.After treatment,the score of objective support,subjective support and utilization of support in the treatment group was higher than that in the control group,and the differences were statistically significant(P＜0.05）.
Conclusion
The psychological intervention of the family members of cancer chemotherapy patients significantly alleviated their depression and anxiety.And psychological intervention reduced the family burden obviously and improved social support.
2018 Vol. 25 (30): 160-163 [
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79
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Application effect of collaborative nursing mode in patients with acute myocardial infarction
XIONG Chun-ru
Objective
To explore the application effect of collaborative nursing mode in patients with acute myocardial infarction(AMI).
Methods
A total of 72 cases of AMI in our hospital from March 2015 to April 2018 were selected as the research object.The selected objects were divided into experimental group and control group according to the random number table method,36 cases in each group.The control group was used the routine nursing intervention,and the experimental group was used with the cooperative nursing mode.The cardiac function indexes,such as the B type natriuretic peptide precursor at the end of N(NT-proBNP)level and the left ventricular ejection fraction(LEVF)value after the intervention of the two groups,and the changes of the psychological condition after the intervention of the two groups were compared.
Results
After the intervention,the NT-proBNP level in the experimental group was significantly lower than that in the control group,and the LEVF value was significantly higher than that of the control group(P<0.05）.Before the intervention,there was no significant difference between the two groups of Hamilton anxiety scale(HAMA)and Hamilton Depression scale(HAMD)scores(P＞0.05）.The scores of HAMA and HAMD in the two groups were lower than those before the intervention,and the experimental group was significantly lower than that in the control group(P<0.05）.
Conclusion
The cooperative nursing mode for patients with AMI can reduce the negative emotion of the patients and improve the cardiac function after treatment,so as to improve the prognosis and improve the quality of life.
2018 Vol. 25 (30): 164-166 [
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97
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Effect of comprehensive nursing intervention on nosocomial infection in intensive care unit
CAI Chun-mei
Objective
The monitoring and nursing intervention methods of nosocomial infection in intensive care unit(ICU)were analyzed.
Methods
A total of 98 cases of ICU admitted in our hospital from January 2016 to March 2018 were selected and by random digital table divided into the control group and observation group,49 cases in each group.The control group was received routine nursing,the observation group was received comprehensive nursing.The clinical nursing status of the two groups,including the infection rate of patients and nursing quality score,were compared and analyzed.
Results
The infection rate of patients in the observation group (8.16%)was lower than that in the control group(32.65%).The scores of basic nursing([18.06±0.38]scores,professional skills[17.53±0.57]scores,service attitude[18.90±0.46]scores,comprehensive service [18.13±0.58]scores)were significantly higher than those of control group([13.54±0.73]scores,[12.37±0.60]scores,[12.08±0.31]scores,[12.03±0.56]scores,[12.67±0.47]scores),the differences were statistically significant(P<0.05）.
Conclusion
The probability of infection in the patients in the ICU is higher,and comprehensive nursing intervention should be given according to the actual situation of the patients.In order to prevent or reduce the incidence of infection,the clinical nursing effect is better.
2018 Vol. 25 (30): 167-169 [
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65
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Study the clinical effect of acupuncture combined with traditional Chinese medicine nursing on patients with wind chill facial paralysis
LI Yun;LAI Hua-ping;CHEN Juan
Objecttive
To study the clinical effect of acupuncture treatment combined with traditional Chinese medicine nursing intervention on patients with wind chill facial paralysis.
Methods
A total of 50 patients with cold type facial paralysis treated in our hospital from October 2016 to September 2017 were selected.They were divided into control groups and observation group by random number table method,25 cases in each group.The patients in control group were treated with routine acupuncture,and the patients in observation group were treated with acupuncture and traditional Chinese medicine nursing intervention.After treatment,the facial nerve functional classification scale(H-B),depression scale(SDS)and anxiety scale(SAS)were observed in the two groups.
Results
The normal rate of facial nerve recovery in the observation group(72.00%)was higher than that in the control group(40.00%)(P<0.05）.After treatment,the scores of SDS and SAS in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05）.
Conclusion
Acupuncture combined with traditional Chinese medicine nursing intervention has good clinical effect on patients with wind chill facial paralysis,can effectively improve the condition of patients with wind chill facial paralysis,and promote their rehabilitation,improve the treatment effect and quality of life,which is worth to be used in clinical promotion.
2018 Vol. 25 (30): 170-172 [
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89
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Effects of individualized nursing interventions on sleep and quality of life in perimenopausal women with insomnia
JIANG Yue-mei
Objective
To analyze the effects of individualized nursing intervention on sleep status and quality of life in perimenopausal patients with insomnia.
Methods
A total of 114 cases of perimenopausal insomnia treated in our hospital from August 2015 to August 2017 were selected.They randomly were divided into the control group and the observation group,57 cases in each group.The control group was received routine nursing intervention,and the observation group was received individualized nursing intervention.The scores of sleep disorders and quality of life,the normal time of sleep recovery and the total time,the effect of treatment and the satisfaction of nursing mode and adverse events were compared before and after the nursing intervention in the two groups.
Results
The improvement of sleep disorder score and quality of life score in the observation group was higher than that of the control group before and after nursing intervention.The differences were statistically significant(P<0.05）.The recovery time and the total time of the treatment were shorter than those in the control group(P<0.05）.The total effective rate of the disease treatment and the degree of satisfaction to nursing in the observation group mode were higher than those in the control group,the difference was statistically significant(P<0.05）,and the incidence of adverse events was lower than that of the control group(P<0.05）.
Conclusion
The individual nursing intervention during the period of perimenopausal insomnia can improve the sleep and life quality of the patients in a short time,reduce the adverse events,shorten the time of treatment,improve the effect of treatment and the satisfaction of the patient to the nursing service.
2018 Vol. 25 (30): 173-175 [
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81
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Application of path management in nursing care of hospitalized patients with stroke
YI Yuan-zhen;GU Yu-hua;GUO Chun-hong;PAN Huo-ying
Objective
To study the clinical effect of path management in nursing care of hospitalized patients with stroke.
Methods
A total of 30 cases of hospitalized stroke patients received in our hospital from April to December 2017 were selected divided into two groups of bladder nursing measures by random extraction,15 cases in each group.The control group was used routine clinical nursing measures,the study group was carried out the path management on this basis.The application effect of two kinds of nursing care were compared.
Results
The nursing coordination degree and knowledge of bladder nursing in the study group were significantly higher than those in the control group(P<0.05）.The catheter retention time of the patients in the study group was shorter than the control group and the extubation rate was higher than that of the control group(P<0.05）.The interval time of nocturnal urine in the study group was significantly higher than that of the control group (P<0.05）.The number of urine leakage in the study group was longer than that of the control group and the number of 24 h was less than the control group.The differences were statistically significant(P<0.05）.The nursing satisfaction of the patients in the study group was significantly higher than that of the control group(P<0.05）.
Conclusion
The effect of path management on bladder nursing in patients with cerebral pawns is obvious in clinical.It can improve the cognition of bladder nursing and improve the urination of the patients.It is worth to use.
2018 Vol. 25 (30): 176-178 [
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82
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Application effect of systematic midwife out-patient service in improving delivery process and delivery outcome of primipara
CHEN Xing-mei;MO Shi-yan
Objective
To explore the application effect of systematic midwife out-patient service in improving delivery process and delivery outcome of primipara.
Methods
A total of 200 primiparas from June 2017 to June 2018 in the outpatient department of our hospital were selected randomly divided into control group and observation group,100 cases in each group.The control group was received routine prenatal examination and prenatal education.The observation group was added the systematic midwife outpatient serviceon on basis of the control group.The delivery mode,time of labor,the amount of postpartum hemorrhage,and the neonatal score were compared in the two groups.
Results
The rate of cesarean section in the observation group was significantly lower than that of the control group,postpartum hemorrhage in the observation group was significantly lesser than that of the control group(P<0.05）,and the time of delivery and the total labor time in the observation group were significantly shorter than those in the control group (P<0.05）,and the satisfaction of the observation group was significantly higher than that of the control group,the differences were statistically significant(P<0.05）.
Conclusion
The midwife outpatient clinic can promote the harmonious development of the nurse-patient relationship,shorten the production process reduce the postpartum hemorrhage,reduce the rate of cesarean section and improve the quality of obstetric nursing service.It is worth popularizing in clinical practice.
2018 Vol. 25 (30): 179-181 [
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87
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Application effects of comfortable nursing in treating bleeding of peptic ulcer and nursing method
XIE Xiao-xia;OU Jian-ai;LIANG Wei-ying;LIAO Yan-qin
Objective
To explore the effect of comfortable nursing in peptic ulcer bleeding patients treating by micropump.
Methods
A total of 100 cases with peptic ulcer bleeding treated in our hospital from September 2016 to September 2017 were selected as the research object,they were all treated with randomly divided into two groups,50 cases in each group.All patients were treated with continuous infusion of microinjector of octreotide.Patients in the control group were nursed by traditional nursing method,while patients in the observation group were given the comfortable nursing method.The curative effect,bleeding and hemostasis of the two groups,the average length of hospitalization and the nursing satisfaction of two groups were compared.
Results
The total effective rate of the observation group was higher than control group,the difference was statistically significant(P<0.05）.The average bleeding times,hemostasis time and hospitalization time in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05）.The total nursing satisfaction rate of patients in the observation group was higher than that in control group,the difference was significant(P<0.05）.
Conclusion
The treatment of patients with peptic ulcer hemorrhage with micropump can significantly improve the treatment effect,reduce bleeding effectively,improve nursing satisfaction,and deserve clinical promotion.
2018 Vol. 25 (30): 182-184 [
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71
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Application effect of human-centered holistic nursing in patients with pulmonary tuberculosis complicated with hemoptysis
LI Li
Objective
To observe the effect of human-based holistic nursing in patients with pulmonary tuberculosis（PTB） complicated with hemoptysis.
Methods
A total of 70 patients who suffered from phthisis with hemoptysis accepted by our hospital from December 2016 to February 2018 were taken as the research subjects,they were divided into observation group (35 patients)and control group (35 patients)according to stochastic method.The patients in the control group were conducted with conventional nursing method for hemoptysis,while the patients in the observation group were conducted with human-orientation entire nursing method based on conventional nursing method for hemoptysis.Then the clinical nursing effect indexes,nursing satisfaction and SAS grade for the two groups were compared.
Results
The effective control rate for hemoptysis for the patients in the observation group was higher than that in the control group,the difference was of statistical significance (P<0.05）;the total nursing satisfaction for the observation group was 97.1%,higher than 82.9%for the control group,the difference was of statistical significance(P<0.05）;and the SAS grade for the observation group was lower than that of the control group,the difference was of statistical significance(P<0.05）;while as for comparison of general clinical data between the two groups,the difference had no statistical significance(P ＞0.05）.
Conclusion
The patients with hemoptysis in our hospital have achieved satisfactory results by using the holistic nursing of human-based.It is of great significance to accelerate the course of disease,improve the SAS score and improve the nursing satisfaction of the patients.
2018 Vol. 25 (30): 185-187 [
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78
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188
Effect of predictive nursing on postoperative pain，complications and quality of life in patients with limb fractures
HUANGFU Zhen-zhen
Objective
To explore the effect of predictive nursing on postoperative pain,complications and quality of life in patients with limb fractures.
Methods
A total of 82 cases of extremities fracture treated in our hospital from March 2016 to February 2018 were selected and randomly divided into study group and control group according to the single and double number of admission order,41 cases in each group.The control group was given routine care,and the study group was given predictive care based on the control group.The postoperative pain,complications,and quality of life were compared between the two groups.
Results
The pain degree of 72 h in the two groups was significantly lighter than that of postoperative 24 h (P<0.05）.The pain degree of 24 and 72 h in the study group was significantly lighter than that of the control group (P<0.05）,and the incidence of complications in the study group was significantly lower than that of the control group (P<0.05）.The scores of the quality of life after nursing in the two groups were significantly higher than those before nursing(P<0.05）.The scores of quality of life in the study group were significantly higher than those in the control group,the differences were statistically significant(P<0.05）.
Conclusion
Predictive care has significant clinical effect on patients with limb fractures.It can effectively improve postoperative pain,reduce the incidence of complications and improve quality of life.It is worthy of clinical application.
2018 Vol. 25 (30): 188-190 [
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72
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191
Application effect of high-quality nursing on the nursing of elderly patients with painless myocardial ischemia
XU Li-juan;CHENG Li;GONG Na
objective To explore the application value of high quality nursing in elderly patients with painless myocardial ischemia.（SMI）.
Methods
A total of 120 aged patients with SMIadmitted in our hospital from January 2015 to December 2016 were selected and divided into observation group (n=60)and control group (n=60)according to random number table method.The patients in control group were treated with routine nursing mode.The patients in the observation group were treated with high quality nursing mode.The recovery,sleep quality and nursing effect of the two groups were compared.
Results
After the same treatment cycle,the incidence of abnormal blood pressure and heart rate in the observation group was significantly lower than that in the control group (P<0.05）,and the PSQI score of Pittsburgh Sleep quality Index scale was lower than that of the control group (P<0.05）.The satisfaction of the patients in the observation group was significantly higher that in the control group,and the differences between the two groups were statistically significant(P<0.05）.
Conclusion
The application of high quality nursing therapy in the treatment of senile patients with SMIis helpful to the progress of recovery,improve the quality of sleep and improve the satisfaction of patients.It is worth popularizing and applying.
2018 Vol. 25 (30): 191-193 [
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63
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194
Application effect of PDCA cycle management in hemodialysis nursing
WAN Guo-lin;QIU Feng-lin
Objective
To explore the application of plan-do-check action (PDCA)cycle management in hemodialysis nursing.
Methods
Sixty patients who underwent hemodialysis in our hospital from January 2016 to December 2017 were enrolled in the study.They were divided into control group and observation group according to the patient′s admission order,30 patients in each group.Patients in the control group were provided with routine dialysis care intervention,and patients in the observation group were supplied with PDCA cycle management.The quality of life and patient′s satisfaction were compared between the two groups.
Results
After different nursing interventions,the rehabilitation of the observation group was significantly better than that of the control group.The quality of life score of the observation group was higher than that of the control group with statistical significance(P<0.05）.Patient′s nursing satisfaction was significantly higher in the observation group than the control group with a significant difference (P<0.05）.
Conclusion
PDCA cycle management as a nursing intervention for hemodialysis patients can effectively improve the patient′s treatment prognosis,and to some extent,increase the patient′s nursing satisfaction,and reduce the patient′s adverse events and incidence of complications,which is of great significance for clinical promotion.
2018 Vol. 25 (30): 194-196 [
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65
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197
Application effect of preventive nursing measures for adverse reactions in percutaneous transforaminal discectomy
ZHONG Mei-lian
Objective
To investigate the preventive and nursing measures for adverse reactions of percutaneous transforaminal discectomy.
Methods
From January 2016 to March 2017,92 patients with lumbar disc herniation underwent percutaneous transforaminal discectomy in our hospital were enrolled.According to envelope randomization,they were equally divided into regular group and experimental group,46 cases in each group.In the regular group,traditional nursing measure was used,while in the experimental group,preventive nursing measure on adverse reactions was provided.The nursing effect in the two groups was compared.
Results
The postoperative exhaust time,postoperative offbed time and hospital stay were significantly shorter in the experimental group than in the regular group(P<0.05）.The hospitalization cost in the experimental group was significantly lower than that in the regular group(P<0.05）.The visual analogue scale(VAS)score of the experimental group was significantly lower than that of the regular group(P<0.05）.The incidence of adverse reactions in the experimental group and the regular group were 8.70%and 23.91%,respectively,and the incidence of adverse reactions in the experimental group was lower,the differences were statistically significant(P<0.05）.
Conclusion
The preventive nursing on adverse reactions in patients undergoing percutaneous transforaminal discectomy can reduce the incidence of adverse reactions,shorten the hospital stay,and promote the early recovery of the disease.
2018 Vol. 25 (30): 197-199 [
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67
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200
Application effect of continuous humanistic care in the nursing of electronic laryngoscopy
SHANG Hong-wei
Objective
To explore the application effect of continuous humanistic care in the nursing of electronic laryngoscopy.
Methods
A total of 600 patients who underwent electronic laryngoscopy in our hospital from February 2017 to February 2018 were enrolled in the study.They were divided into observation group and control group by a random number table,300 cases in each group.In the control group,regular nursing during examination was used,while in the observation group,continuous humanistic care was carried out.The nursing satisfaction of the two groups through questionnaire survey was collected.The incidence of negative emotions between the two groups was compared.
Results
In the observation group,the satisfaction of nursing performance,examination environment,health education and service attitude was higher than that of the control group,with statistical significance (P<0.05）.The incidence of negative emotions in the observation group was 5.0%,significantly lower than that of the control group accounting for 14.7%,with statistical significance (P<0.05）.
Conclusion
Continuous humanistic care in the nursing of electronic laryngoscopy is beneficial to alleviate negative emotions and improve nursing satisfaction,which is of great clinical significance.
2018 Vol. 25 (30): 200-202 [
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77
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203
Effect of comfortable nursing on prevention of deep vein thrombosis in patients with multiple fractures of lower extremities
LI Yuan
Objective
To study the effect of comfortable nursing on the prevention of deep vein thrombosis in patients with multiple fractures of lower extremities.
Methods
From May 2015 to August 2017,84 patients with multiple fractures of lower extremity admitted into our hospital were enrolled and randomly divided into two groups for nursing,42 cases in each group.In control group,routine clinical nursing was used,while in research group,on the basis of the control group,comfortable nursing was adopted.The effect of two nursing methods to prevent deep vein thrombosis was comapred.
Results
The rate of deep vein thrombosis in the research group was lower than that in the control group(P＜0.05）.The hospital stay of the research group was shorter,the quality of life score was higher,and visual analogue scale score was lower compared with those of the control group,with statistical significance(P＜0.05）.
Conclusion
Clinically，the use of comfortable nursing to treat patients with multiple fractures of the lower extremities can effectively prevent the occurrence of deep vein thrombosis and is worthy of promotion.
2018 Vol. 25 (30): 203-205 [
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75
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206
Effect of Case-based nursing management combined with continuous nursing on breast cancer fatigue and life quality
LI Hong-mi;LOU Hui
Objective
To explore the effect of case-based nursing combined with continuous nursing on breast cancer fatigue and life quality.
Methods
A total of 80 cases with breast cancer in our hospital from January 2017 to May 2018 were selected.They were divided into control group and observation group according to rondom number table method,40 cases in each group.The control group was given continuous nursing after discharge.The observation group was implemented case-based nursing management combined with the continuous nursing intervention,all were related situation was evaluated 2 weeks,and the changes of the piper cancer fatigue （PFS）scores after the intervention were compared,the sleep quality of all the participants before and after the intervention were analyzed.The life quality of KPS before and after intervention were compared.
Results
After intervention,the scores and total scores of the PFS in the observation group were significantly lower than control group (P＜0.05）.After the intervention,the sleep quality in the observation group was lower than post-intervention control group (P＜0.05）,the KPS life quality score in the observation group was higher than control group,the differences were statistically significant(P<0.05）.
Conclusion
Casebased nursing intervention combined with continuous nursing intervention can reduce the cancer fatigue index during breast cancer,so it can improve the sleep quality and life quality.
2018 Vol. 25 (30): 206-208 [
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78
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209
The clinical effect of health education in the nursing of pelvic inflammatory disease
WU Min;ZHONG Yan-ling;ZHOU Xiang-yuan
Objective
To analyze the clinical effect of health education in the nursing of pelvic inflammatory disease（PID).
Methods
A total of 88 cases of PID treated in our hospital from April 2016 to January 2018 were selected as the research object.According to the different clinical nursing methods,all patients were divided into the control group(42 cases)and the study group (46 cases).The control group was given the routine nursing,and the study group was given the health education on the basis of the control group.The clinical nursing effects of the two groups were compared.
Results
There was no significant difference in the knowledge of disease and nursing knowledge before nursing between the two groups of(P＞0.05）.The scores of patients with PID and nursing knowledge in the study group after nursing were higher than those in the control group,the differences were statistically significant(P<0.05）.The nursing satisfaction and compliance rate of the patients in the study group were 95.65%,97.83%,respectively,which were significantly higher than those in the control group of 80.95%and 85.71%,the differences were statistically significant(P<0.05）.
Conclusion
Strengthening health education in the nursing of patients with PID can improve the satisfaction of nursing and patient compliance,it is conducive to master the knowledge of PID and related nursing knowledge,which has important application value.
2018 Vol. 25 (30): 209-211 [
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71
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Health education and psychological care in elderly upper abdominal application effect of MRI enhanced examination
WAN Xiao-ling
Objective
To investigate the effect of health education and psychological nursing on MR imaging in the elderly upper abdomen.
Methods
Sixty-eight elderly patients who underwent MR enhanced examination in our hospital from January 2017 to January 2018 were selected for study.The patients were divided into control group and observation group according to a 1∶1 approach,34 cases in each group.The control group was treated with routine nursing interventions,the observation group were provided with health education and psychological care.The effect of nursing care was compared between the two groups.
Results
The two groups of patients completed the examination successfully.Before the intervention,there was no significant difference in anxiety(SAS)mood between the two groups(P＞0.05）.After the intervention,the SAS scores in the observation group were significantly lower than those in the control group,the difference was statistically significant(P<0.05）.The compliance of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05）.
Conclusion
Understanding the causes of anxiety in the elderly patients with MR enhanced examination of the upper abdomen,and the implementation of health education and psychological care for the patients can significantly improve the patient′s emotions,promote the successful completion of the examination,provide a reliable basis for clinical diagnosis,and it is worth popularizing and applying.
2018 Vol. 25 (30): 212-214 [
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79
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215
Preventive effect of cluster nursing on ventilator-associated pneumonia（VAP）and lung function in newborn
LUO Dan;YANG Mei-jun
Objective
To discuss the effect of cluster nursing in preventing the ventilator-associated pneumonia(VAP)and lung function in newborn.
Methods
A total of 74 neonates who underwent mechanical ventilation from January to December 2017 were selected as research subjects,and divided into control group and observation group according to random number table method,37 cases in each group.The two groups of neonates were given routine nursing,while the observation group was received cluster nursing at the same time.The incidence of VAP in the two groups was compared,and the pulmonary function index(PEF,FRC and TEF25%)before and after nursing were measured,and the mechanical ventilation time and the time of hospitalization were recorded and compared in the two groups.
Results
The incidence of VAP in the observation group and control group were 16.22%(6/37)and 37.84%(14/37)respectively,the difference was statistically significant(P<0.05）.There were no differences in lung function indexes such as PEF,FRC and TEF25%in the two groups before nursing(P＞0.05）,and the levels of PEF,FRC and TEF25%in the observation group were higher than those in control group after nursing(P<0.05）.The time of mechanical ventilation and length of stay in the observation group were shorter than those in control group,and the differences were statistically significant(P<0.05）.
Conclusion
Cluster nursing can effectively prevent the incidence of neonatal VAP,and protect the pulmonary function of newborns,as well as shorten the time of mechanical ventilation and hospitalization,which is worthy of clinical application.
2018 Vol. 25 (30): 215-217 [
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85
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Effect of wechat-based nursing care in perioperative period of out-patient tooth extraction
WU Xiao;LI Wei;ZHOU Jun
Objective
To explore the effects of wechat-based nursing care in the peri-operative period of out-patient tooth extraction.
Methods
From April 2016 to April 2018,100 patients in the peri-operative period of out-patient tooth extraction were selected as the subjects and divided into the control group and the observation group according to random number table method,50 cases in each group.The observation group was performed the health education,psychological care and post-operative nursing care by wechat.The control group was performed routine the health education,psychological care.Postoperative systolic blood pressure,temperature,heart rate,anxiety,pain,the satisfaction and complication rate were compared between two groups.
Results
Postoperative,the systolic blood pressure,heart rate of the observation group were significant lower than that in the control group,the HAMA anxiety scale and VAS of the observation group were significant lower than that in the control group (P<0.05).The satisfaction scale of the observation group was higher than that in the control group,the differences were statistically significant(P<0.05).There were no significant difference in the temperature and the total complication rate between the two groups(P＞0.05).
Conclusions
The observation group has peri-operative period of out-patient tooth extraction,which get more safe,less pain and anxious,higher satisfaction.
2018 Vol. 25 (30): 218-220 [
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82
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