自动腹膜透析与连续性肾替代疗法治疗重症急性胰腺炎的效果对比

Abstract
Figure/Table
References (20)
Related Citation (9)

Download: PDF (0 KB) HTML (46 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To compare the effect of automated peritoneal dialysis(APD)and continuous renal replacement therapy(CRRT)in the treatment of severe acute pancreatitis(SAP).Methods The clinical data of 76 patients with SAP diagnosed in Guizhou Provincial People′s Hospital and received blood purification therapy from October 2012 to December 2017 were retrospectively analyzed.According to the different treatment,they were divided into the APD group(39 cases)and the CRRT group (37 cases).The relief times of abdominal pain and distension,recovery times of serum and urine amylase levels were compared between the two groups,the changes of Balthazar CT score,APACHEⅡscore,the levels of interleukin-6(IL-6),C-reactive protein(CRP),procalcitonin(PCT)and tumour necrosis factor α(TNF-α)were compared at the 3 and 7 days after treatment.Results The relief times of abdominal pain and distension and recovery times of amylase levels in the APD group were significant shorter than those in the CRRT group,with significant difference(P＜0.05).The Balthazar CT score,APACHE Ⅱ score,the level of IL-6,CRP,PCT and TNF-α in the APD group were lower than those in the CRRT group,with significant difference(P＜0.05).Conclusion APD in the clinical treatment of SAP is significant effective,and which is worthy for popularizing application.

Key words： Automated peritoneal dialysis Continuous renal replacement therapy Severe acute pancreatitis

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	WU Jing
	MA Guo-ying
	CHEN Shuang
	CUI Meng-bi
	YANG Yu-qi
	ZHA Yan

Cite this article:

WU Jing,MA Guo-ying,CHEN Shuang, et al. Comparison of the effect of automated peritoneal dialysis and continuous renal replacement therapy in the treatment of severe acute pancreatitis[J]. 中国当代医药, 2018, 25(30): 4-07.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I30/4

[1]	江结华，刘彩琴，吴苑清.CRRT治疗重症急性胰腺炎临床疗效观察及护理[J].现代医药卫生，2017，33（13）：2045-2046.
[6]	中华医学会外科学分会胰腺外科学组.急性胰腺炎诊治指南（2014）[J].中华外科杂志，2015，53（1）：50-53.
[2]	Feng C，Li B，Wang LL，et al.Effect of peritoneal lavage with ulinastatin on the expression of NF-κB and TNF-α in muhiple organs of rats with severe acute pancreatitis[J].Exp Ther Med，2015，10（6）：2029-2034.
[3]	Wang XY，Tang QQ，Zhang JL，et al.Effect of SB203580 on pathologic change of pancreatic tissue and expression of TNF-α and IL-1β in rats with severe acute pancreatitis[J].Eur Rev Med Pharmacol Sci，2014，18（3）：338-343.
[4]	Guo J，Huang W，Yang XN，et al.Short-term continuous high-volume hemofiltration on clinical outcomes of severe acute pancreatitis[J].Pancreas，2014，43（2）：250-254.
[5]	Sun S，He L，Bal M，et al.High-volume hemofihration plus hemoperfusion for hypedipidemic severe acute pancreatitis：a controlled pilot study[J].Ann Saudi Med，2015，35（5）：352-358.
[7]	Wang Y，Liu W，Liu X，et al.Role of liver in modulating the release of inflanmlatoxy cytokines invdved in lung and multiple organ dysfunction in severe acute pancreatitis[J].Cell Biochem Biophys，2015，7l（2）：765-776.
[8]	韩龙飞，金红旭.早期持续肾脏替代治疗热射病临床疗效分析[J].创伤与急危重病医学，2016，4（5）：286-289.
[9]	唐雯，肖东，刘艳，等.早期行CRRT治疗急性重症胰腺炎的效果观察[J].中外医学研究，2017，15（19）：23-25.
[10]	王莹，繆时星，陈贞素，等.降钙素原动态监测在重症急性胰腺炎患者连续性肾脏替代治疗中的指导价值[J].广东医学，2016，37（14）：2147-2149.
[11]	毛恩强，韩天权，袁祖荣，等.短时血滤对重症急性胰腺炎治疗的影响[J].中华外科杂志，1999，14（3）：12-14.
[12]	杨超，范红，岳伟，等.短期间歇性闭合式腹腔灌洗治疗大鼠早期重症胰腺炎的免疫机制[J].世界华人消化杂志，2013，21（8）：641-646.
[13]	Mahajan A.Current status of role of serum amylase and lipase to triage biunt pancreatic trauma?[J].J Clin Diagn Res，2016，10（11）：PL02.
[14]	杨凡慧，曹龄之，黄晓红，等.姜黄素治疗大鼠脑出血后血清 IL-6、IL-1β、TNF-α 变化的实验研究[J].标记免疫分析与临床，2016，23（9）：1033-1037.
[15]	任麦青.TNF-α和IL-1β在细菌性脑膜炎患儿血清中的表达及其临床意义[J].中国实用神经疾病杂志，2015，18（14）：65-66.
[16]	Merza M，Hartman H，Rahman M，et al.Neotmphil extracellular traps induce trypsin activation，inflammation，and tissue damage in mice with severe acnte panereatitis[J].Gastrcenterology，2015，149（7）：1920-1931.
[17]	Nieminen A，Maksimow M，Mentula P，et al.Circulating cytokines in predicting development of severe acute pancreatitis[J].Crit Care，2014，18（3）：R104.
[18]	赵若愚，鲍逸民，杨永清.血清 PCT、IL-6、NT-proBNP、CTnl和D-D检测水平在急诊脓毒症患者早期诊断中的临床研究[J].标记免疫分析与临床，2016，23（6）：613-616.
[19]	李海锟，陈冬冬，封波，等.PCT、CRP、WBC 检测预警经皮肾术后感染性发热的临床意义[J].青岛医药卫生，2016，48（1）：1-5.
[20]	Matsumoto K，Miyake Y，Naka′isu M，et al.Usefulness of early-phase peritoneal lavage for treating severe acute pancreatitis[J].Int Med，2014，53（1）：1-6.