无创通气治疗联合复方异丙托溴铵治疗慢性阻塞性肺疾病合并呼吸衰竭的效果

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Abstract Objective To investigate the effect of non-invasive ventilation combined with Compound Ipratropium Bromide in the treatment of respiratory failure in patients with chronic obstructive pulmonary disease(COPD).Methods A total of 60 patients with COPD and respiratory failure treated in our hospital from October 2015 to March 2017 were selected.They were randomly divided into the control group and the observation group,with 30 cases in each group.The control group was assisted by non-invasive ventilation on the basis of routine treatment.The patients in the observation group were added with the Compound Isoprominium Bromide on the basis of the control group,and the effect of intervention was compared between the two groups.Results After treatment,the PaO2and pH values in the observation group were higher than those in the control group (P＜0.05),and PaCO2was lower than that in the control group (P＜0.05).The FEV1and FEV1/FVC of the observation group after treatment were higher than those of the control group(P＜0.05).The hospitalization time and mechanical ventilation time in the observation group were shorter than those in the control group,after 7 d treatment,the heart rate of the observation group was slower than that of the control group,and the incidence of ventilator-associated pneumonia was lower than that of the control group (P＜0.05).Conclusion The combination of non-invasive ventilation and Compound Ipratropium Bromide for patients with COPD combined with respiratory failure can improve the index of arterial blood gas analysis and pulmonary function.It is worth promoting in clinical work.

Key words： Non-invasive ventilation Compound Ipratropium Bromide Respiratory failure Complication

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	WANG Yi

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WANG Yi. Effect of non-invasive ventilation combined with Compound Ipratropium Bromide in the treatment of chronic obstructive pulmonary disease with respiratory failure[J]. 中国当代医药, 2018, 25(30): 60-62-69.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I30/60

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