改良腹腔穿刺置管引流术联合腹腔内注射托拉塞米、多巴胺治疗肝硬化并难治性腹水的临床效果

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Abstract Objective To investigate the clinical efficacy of modified abdominal puncture drainage combined with intraperitoneal injection of Torsemide and Dopamine in the treatment of cirrhosis and refractory ascites.Methods A total of 60 patients with cirrhosis and refractory ascites hospitalized in our hospital from January 2016 to December 2017 were selected as the study subjects,and they were randomly divided into the control group(30 cases)and the observation group(30 cases).The control group received routine treatment measures such as liver protection,enzyme lowering,diuretic detumescence,protein supplementation and electrolyte balance,and antiviral treatment for viral hepatitis patients.A modified central venous catheter was used for intraperitoneal indwelling drainage.In the observation group,20 mg of Dopamine Hydrochloride and 20-40 mg of Tolasemine were injected into the abdominal cavity at the same time every other day on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of the observation group was 90%,which was higher than 50%of the control group,and the difference was statistically significant(P＜0.05).The improvement of liver function indexes in the observation group was better than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Modified abdominal puncture drainage combined with intraperitoneal injection of Torsemide and Dopamine in the treatment of cirrhosis and refractory ascites can synergistically improve the clinical treatment effect,which can be further promoted and applied.

Key words： Cirrhosis Refractory ascites Intraperitoneal injection Torasemide Dopamine

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	Articles by authors
	LAI Jian-rong
	YI Pei-zhuang
	ZHOU Qi-ming
	CHEN Yuan-hui
	DUAN Xiao-ping

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LAI Jian-rong,YI Pei-zhuang,ZHOU Qi-ming, et al. Clinical effect of modified abdominal puncture drainage combined with intraperitoneal injection of Torsemide and Dopamine in the treatment of cirrhosis with refractory ascites[J]. 中国当代医药, 2018, 25(30): 42-44.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I30/42

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