中国当代医药
      Home                              中文
中国当代医药
 
Forthcoming Articles
Current Issue
Archive
Advanced Search
Read Articles
Download Articles
Email Alert
 
Quick Search  
  Adv Search
2017 Vol. 24, No. 30
Published: 2017-10-28
 
 
4 Renal toxicity comparison of different doses of isotonic and hypotonic contrast agents in the interventional diagnosis of cerebrovascular disease
ZHOU Yang;ZHOU Xiao-bing;YIN Jin-feng
ObjectiveTo contrast the renal toxicity of different doses and different types of contrast agents in the diagnosis of cerebrovascular disease intervention.Methods300 cases with cerebrovascular disease in the Department of Neurosurgery of the First Hospital Affiliated to Nanchang University from July 2015 to May 2017 were selected as objects,and all patients were randomly divided into isotonic contrast agents group and hypotonic contrast agents group,and there were 150 cases in each group.According to the imaging findings and their families will,patients without surgery or intends to do surgical operation were divided into small dose of contrast agents group with no longer injection of contrast agents.Patients given immediately endovascular treatment of cerebrovascular disease were divided into large dose of contrast agents group injected with the same type contrast agents.42 cases were divided into small dose of isotonic contrast medium group,108 cases were divided into large dose of isotonic contrast medium group,51 cases were divided into small dose of hypotonic contrast agents group,99 cases were divided into large dose of hypotonic contrast agents group.Serum cystatin C(CysC),serum creatinine(SCr)before,and at 24 h,48 h,72 h after operation among various groups were compared.ResultsThe level of CysC and SCr in all groups were higher than before the operation (P＜0.05).The incidence of contrast nephropathy (CIN),CysC and SCr level in small dose group were lower than those of large dose group with the same type contrast agents(P＜0.05).CysC level of large dose of isotonic contrast medium group was significantly reduced compared with large dose of hypotonic contrast agents group(P＜0.05),but there was no statistically significant difference in the incidence of CIN and SCr level(P＞0.05).ConclusionThe renal toxicity of the contrast medium is related to the dosage of the drug.Isotonic contrast agents is safer than low-osmolar contrast agents in large dosage.
2017 Vol. 24 (30): 4-7 [Abstract] ( 165 ) HTML (44 KB)  PDF  (0 KB)  ( 69 )
8 Meta-analysis of Glutaraldehyde vs Ethanol for disinfection of Penicillin skin test
LI Xia-xi;LIU Cui-ping;LIU Xing-xing;DU Meng;FU Cai-yan
ObjectiveTo evaluate the influence of Glutaraldehyde cleaning vs Ethanol disinfection on Penicillin skin test result in the published literatures in China.MethodsRandomized controlled trials(RCT)in Glutaraldehyde vs Ethanol applied in Penicillin skin test were searched and screened in CBM,CNKI,VIP,Wanfang,PubMed,Cohrance database and so on.The retrieval time was from database building to January,2017.The literature was screened according to the inclusion and exclusion criteria decided by the evaluation research quality.Meta-analysis was conducted using Review Manager 5.0 software.ResultsTotally 4 studies were eligible to the criteria in 113 literatures reviewed.Meta-analysis showed there was significant difference between Glutaraldehyde and Ethanol groups∶I2＝0% (OR＝0.16,95%CI＝0.11-0.22,P＜0.00001),but publication bias may exaggerate the effect of Glutaraldehyde.ConclusionGlutaraldehyde has lower false positive rate compared with Ethanol,but further studies are needed in proving whether Glutaraldehyde can replace Ethanol in penicillin skin test.The quality of the included studies is not high,the above conclusions are verified by developing more high-quality randomized double-blind controlled trials.
2017 Vol. 24 (30): 8-10 [Abstract] ( 172 ) HTML (34 KB)  PDF  (0 KB)  ( 65 )
11 Summary of emergency support of traditional Chinese medicine in disaster and public health emergency
HUANG Yi-fu;HUANG Yin;DONG Yi-zhu;LIAO Shao-fen
Traditional Chinese medicine plays an important role in emergency rescue of disasters and public health emergencies.In this paper,the emergency guarantee situation of traditional Chinese medicine was summarized.The advantages of traditional Chinese medicine in medical emergency rescue,the system construction,reserve construction and the protection in emergency rescue of proprietary Chinese medicine were summarized,and the strategy to enhance the ability of traditional Chinese medicine emergency support was summarized.The future health emergency rescue work can be both Chinese and Western medicine is expected,and provide reference and basis for the emergency rescue area of traditional Chinese medicine.
2017 Vol. 24 (30): 11-14 [Abstract] ( 166 ) HTML (39 KB)  PDF  (0 KB)  ( 77 )
15 Analysis on the curative effect of the treatment of mixed hemorrhoids with indentation and hemorrhage
CHEN Guang-hua;TANG Xiao-xia;ZHANG Gong-yu
ObjectiveTo explore the clinical effect of external incision indocting hemorrhoid and external stripping ligation in the treatment of mixed hemorrhoids.MethodsFrom July 2014 to March 2016,82 patients who were treated with mixed hemorrhoids in our hospital were included in the study and grouped according to the random data table.41 cases of the control group were treated with external stripping and ligation.The use of external injection Note Xiao Ling,clinical efficacy were compared.ResultsThe healing time,pain relief time and average hospitalization time were lower in the observation group than that in the control group,the difference was statistically significant(P＜0.05),The total effective rate was 95.12%in the control group and 97.56%in the observation group.There was no significant difference between the two groups(P＞0.05).The complication rate and recurrence rate were 4.88%and 0.00%,respectively,which were 24.39%and 14.64%lower than those in the control group,the difference was statistically significant(P＜0.05).ConclusionThe external treatment of hemorrhoids and indigestion and ligation are obvious,but the former is small,can effectively reduce the VAS score,shorten the hospital stay,promote wound healing,and the incidence of complications is low,it is worth promoting.
 
2017 Vol. 24 (30): 15-17 [Abstract] ( 195 ) HTML (33 KB)  PDF  (0 KB)  ( 75 )
18 Clinical study of the incidence of extra-esophageal symptoms and risk factors in patients with gastroesophageal reflux diseases
JIE Su-ping;HUANG Hai-hua;CHEN Dong-yun
ObjectiveTo investigate the incidence and risk factors of extra-esophageal symptoms in patients with gastroesophageal reflux diseases.MethodsA total of 100 patients with gastroesophageal reflux diseases from May to August in 2016 treated in our hospital were retrospectively analyzed.The incidence of extra-esophageal symptoms was calculated and risk factors were analyzed and summarized.ResultsAmong all these patients,the overall incidence of extraesophageal symptoms was 43.0%.Among them,reflux laryngitis was 51.2%,reflux cough 32.6%,and reflux asthma 16.3%.The risk factors of occurring extra-esophageal symptoms including tiresome,somking,dietary structure,excessive intake and spicy food,and high GERDQ scale score≥8 points.ConclusionTiresome，smokeing,dietary structure,excessive intake,spicy diet,and score of high GERDQ scale≥8 will increase the incidence of extra-esophageal symptoms in patients with gastroesophageal reflux diseases.Therefore,measures should be taken in nursing to prevent the above-mentioned risk factors.
2017 Vol. 24 (30): 18-20 [Abstract] ( 178 ) HTML (30 KB)  PDF  (0 KB)  ( 72 )
21 Analysis of the effect of conservative treatment and surgical treatment of acute simple appendicitis
LI Zhen-kui
ObjectiveTo investigate the clinical effect of conservative treatment and surgical treatment of acute simple appendicitis.Methods130 patients with acute simple appendicitis were enrolled in our hospital from January 2015 to December 2016.The patients were divided into two groups according to the random number table method.The patients were treated with conservative treatment(65 cases in the control group)and Surgical treatment(observation group of 65 cases),compared the two groups of clinical efficacy,antibiotic use time,get out of bed activity time,length of stay,adverse reactions and recurrence.ResultsThere was significant difference between the two groups in the total effective rate(P＜0.05).The observation group had significantly shorter antibiotic use time,bedtime and hospitalization time than the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).fter 6 months follow-up,the recurrence of the patients in the observation group was statistically significant(P＜0.05).There was significant difference between the control group and the control group (P＜0.05).ConclusionThe effect of surgical treatment on patients with acute appendicitis is significant,which is helpful to reduce the antibiotic use time and promote the early rehabilitation of patients.The clinical value is remarkable and worthy of popularization and application.
2017 Vol. 24 (30): 21-23 [Abstract] ( 146 ) HTML (32 KB)  PDF  (0 KB)  ( 76 )
24 The impact of elevated blood glucose on pulmonary function in patients with COPD
ZHENG Hong-yan;WANG Zhi-gang;WANG Mei
ObjectiveTo study the effect of hyperglycemia on pulmonary function of chronic obstructive pulmonary disease(COPD)patients in acute exacerbation stage and clinic remission stage.Methods125 acute exacerbation of chronic obstructive pulmonary disease(AECOPD)patients hospitalized our hospital in Department of Respiratory Medicine from June 2015 to September 2016 were selected.According to the fasting blood glucose level(FBG),the 125 cases were divided into two groups.Forced expiratory volume in one second(FEV1),forced vital capacity(FVC),total lung capacity(TLC),diffusion capacity for carbon monoxide(DLCO)were measured at admission and 6 months after discharge.The relationship of FBG and pulmonary function was analyzed.Results①The levels of TLC and DLCO were both significantly lower in the observation group than those in the control group(P＜0.01）at admission and 6 months after discharge.②At admission，there was a negative correlation of TLC,DLCO and FBG in the observation group,respectively(r＝-0.472,-0.516,allP＜0.01）. ③At 6 months after discharge,there was a negative correlation of TLC,DLCO and FBG in the observation group,respectively(r＝-0.465,-0.528,allP＜0.01）.④There was no significant difference between the two groups in FEV1,FVC and FEV1/FVC(P＞0.05）.ConclusionLung diffusing capacity and restrictive ventilatory dysfunction of AECOPD with hyperglycemia are further damaged，obstructive ventilatory disturbance is not damaged.Making a strict glucose control on AECOPD patients in hospitalization is necessary.
2017 Vol. 24 (30): 24-26 [Abstract] ( 146 ) HTML (35 KB)  PDF  (0 KB)  ( 49 )
27 Effect of inhaled Glucocorticoid on stable chronic obstructive pulmonary disease
SONG Yan-qin;HUANG Ge; ZHANG Ying-Xuan
ObjectiveTo investigate the therapeutic effect of inhaled Glucocorticoid on stable COPD (chronic obstructive pulmonary disease).Methods60 patients with stable COPD who treated in our hospital from March 2016 to March 2017 were selected.All patients were divided into observation group and control group according to the treatment.methods,30 cases in each group.The control group was treated with routine treatment.The levels of FEV1,FVC,6-min walking distance （6-MWD）,TNF-α (TNF-α),IL-8,dyspnea score,quality of life score,the number of slow-onset pulmonary attack,BMI were measured one month after treatment.ResultsThe scores of FEV1,FVC,6-MWD,BMI and quality of life in the observation group were better than those in the control group,TNF-α,IL-8,dyspnea score and the number of slow-onset pulmonary episodes were lower than those in the control group,difference s were statistically significant(P＜0.05).ConclusionInhaled glucocorticoid treatment is effective in the treatment of stable COPD,and the safety is high.It can improve the pulmonary function of the patients,reduce the number of COPD attacks,reduce the symptoms of dyspnea,and thus continuously improve the quality of life of patients,worthy of clinical application.
2017 Vol. 24 (30): 27-29转32 [Abstract] ( 185 ) HTML (37 KB)  PDF  (0 KB)  ( 70 )
30 Effect of autologous fat transplantation on the treatment of refractory wounds
SUN June-feng;ZENG Hao;TU Jia-jin
ObjectiveTo observe and analyze the clinical efficacy of autologous fat transplantation in the treatment of refractory wounds methods patients with severe facial tissue defect.Methods96 cases from January 2015 to December 2016 in our hospital were caused by traffic accident,were randomly divided group A（n＝48）and group B（n＝48）.group A of patients were treated with autologous fat gransles combined with platelet rich treatment.Group B treated with autologous fat granules combined with platelet rich fibrin treatment.ResultsThe patients in the group B the excellent rate of treatment(85.42%)was significantly higher than that of group A(66.67%),two groups had significant difference（P＜0.05）.Patients of group B with two times of filling rate of 10.42%was significantly lower than that of group A (25.00%),two groups had significant difference （P＜0.05）.Facial filler satisfaction(97.92%)of group B was significantly higher than 89.58%of group A,with significant difference between the two groups （P＜0.05）.ConclusionAutologous fat geanules combined with rich clinical efficacy of platelet fibrin treatment accident caused serious facial tissue defent wound signicantly,two facical filling rate is low,higher satisfaction,is worthy of clinical application.
2017 Vol. 24 (30): 30-32 [Abstract] ( 148 ) HTML (30 KB)  PDF  (0 KB)  ( 46 )
33 Comparison of effects of different methods of administration of Octreotide in the treatment of acute pancreatitis
SHENG Jin-yi
ObjectiveTo compare the effects of different methods of administration of Octreotide in the treatment of acute pancreatitis.Methods80 cases of patients with acute pancreatitis in our hospital from April 2015 to April 2017 were selected,these patients were divided into routine intravenous infusion group(intravenous group,n＝40)and micro infusion pump continuous infusion group(injection pump group,n＝40)according to the methods of administration,the serum IL-1,IL-8,TNF-α,CRP levels,clinical efficacy,nausea and vomiting remission time,abdominal pain relief time,amylase recovery time,hospitalization time,incidences of adverse reactions of the two groups were statistically analyzed.ResultsThe serum IL-1,IL-8,TNF-α,CRP levels of the injection pump group were significantly lower than the intravenous group(P＜0.05),the total treatment efficiency[95.0%(38/40)]was significantly higher than the intravenous group[82.5%(33/40）]（P＜0.05）,the nausea and vomiting remission time,abdominal pain relief time,amylase recovery time,hospitalization time were significantly shorter(P＜0.05),the incidence of adverse reactions[10.0%(4/40)]was significantly lower than the intravenous group[17.5%(7/40)],the difference was statistically significont(P＜0.05).ConclusionThe effect of micro infusion pump continuous infusion is better than routine intravenous infusion in the treatment of acute pancreatitis.
2017 Vol. 24 (30): 33-35 [Abstract] ( 142 ) HTML (34 KB)  PDF  (0 KB)  ( 64 )
36 Clinical effect of different doses of Budesonide combined with Ipratropium Bromide Inhalation on elderly patients with AECOPD
LI Li;JIANG Lan
ObjectiveTo observe the clinical effect of different doses of Budesonide combined with Ipratropium Bromide Inhalation on Elderly patients with AECOPD and the influence on Pulmonary function and arterial blood gas.Methods88 patients with AECOPD from January 2016 to January 2017 were enrolled in this study,which were randomly divided into 44 cases of the observation group and 44 cases of the control group according to the order of the random.The control group were given low dose of Budesonide combined with Ipratropium bromide Inhalation,the observation group were treated with high dose of Budesonide combined with ipratropium bromide Inhalation,both groups had been treated for 7 days.the remission time of symptoms and signs of both group were recorded.The levels of arterial blood gas(PaO2,PaCO2)and pulmonary function (FEV1%predicted,FEV1/FVC)were measured before and 7 days after treatment.After the end of treatment，the clinical efficacy were evaluated,the occurrence of adverse reactions were observed.ResultsThe remission time of symptoms(Wheezing,shortness of breath,coughing)and signs(wheeze,wet rales)in the observation group were significantly shorter than those in the control group,the difference was statistically significant(P＜0.05).ThePaO2,FEV1% predicted value,FEV1/FVC of both group after treatment were significantly higher than before treatment(P＜0.05),the PaCO2was significantly lower than before treatment(P＜0.05),，and The PaO2,FEV1%predicted value,FEV1/FVC of the observation group after treatment were significantly higher than those in the control group(P＜0.05),the PaCO2was significantly lower than that in the control group(P＜0.05).The total effective rate of the observation group was significantly higher than the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P＞0.05).ConclusionHigh doses of budesonide combined with ipratropium bromide inhalation can improve the lung function and arterial blood gas in the treatment of elderly patients with AECOPD,and shorten the time of symptom and symptom relief,improve the clinical treatment effect,but not increase the adverse reaction rate.
2017 Vol. 24 (30): 36-39 [Abstract] ( 181 ) HTML (41 KB)  PDF  (0 KB)  ( 90 )
40 Clinicalevaluation ofendoscopicesophagealstentimplantation for esophageal cancer with stenosis or esophageal fistula
ZHANG Huan;LI Cui-hong;HUANG Wen-yu
ObjectiveTo investigate the clinical effect of endoscopic esophageal stent implantation in patients with esophageal cancer with or with esophageal fistula.Methods50 patients with esophageal cancer with or without esophageal fistula were enrolled in our hospital from September 2010 to August 2017.All patients were divided into two groups according to the treatment method,25 cases in each group.The observation group was treated with esophageal fistula,the control group was treated with endoscopic dilator dilatation.After treatment,the anasomotic diamcter,short-teral carative effect,recurrence rate and the incidence of complications were compared between the two groups.ResultsThe anastomotic diameter,short-term curative effect and stenosis of the observation group were significantly higher than those of the control group.The recurrence rate and complication rate were significantly lower than those in the control group (P＜0.05）.ConclusionEsophageal cancer with stenosis or esophageal fistula patients with endoscopic esophageal stent implantation treatment of short-term effect is significant,with high safety,lower recurrence rate and less complications,can effectively solve the problem of esophageal stenosis,worthy of clinical promotion application.
2017 Vol. 24 (30): 40-42 [Abstract] ( 154 ) HTML (32 KB)  PDF  (0 KB)  ( 51 )
43 Clinical application value of digestive endoscopy in the treatment of upper gastrointestinal bleeding
FU Xin;YI Jian;ZHANG Shan-jin;XIONG Chao-liang
ObjectiveTo explore the clinical application value of digestive endoscopy in the treatment of upper gastrointestinal bleeding.MethodsFrom January 2013 to December 2016,60 patients with upper gastrointestinal bleeding were enrolled from our hospital.By a random number table,the patients were evenly divided into two groups,with 30 cases in each group.In control group,drug conservative therapy was used,while in observation group,digestive endoscopy was adopted.The total effectiveness rate,hemostasis time,time of abating fever,rebleeding rate,incidence of complications were compared between the two groups.ResultsThe total effectiveness rate in the observation group was 93.33%,significantly higher than that in the control group accounting for 73.33%(P＜0.05).The hemostatic time and time of abating fever in the observation group were both shorter in comparison with those in the control group(P＜0.05).The re-bleeding rate and incidence of complications in the observation group were 3.33%and 10.00%,both lower than those in the control group,20.00%and 33.33%respectively,the difference was statistically significant(P＜0.05).ConclusionFor patients with upper gastrointestinal bleeding,application of digestive endoscopy can effectively improve the clinical efficacy,facilitate the hemostasis,and can also obviously reduce the incidence of rebleeding and complications.
2017 Vol. 24 (30): 43-45 [Abstract] ( 146 ) HTML (32 KB)  PDF  (0 KB)  ( 60 )
46 Effect of regular micro-pumped urokinase as a thrombolytic therapy on maintenance hemodialysis patients
ZHANG Min-qiu;CHENG Jing
ObjectiveTo investigate the effect of regular micro-pumped urokinase as a thrombolytic therapy on maintenance hemodialysis(MHD)patients.MethodsFrom December 2015 to March 2017,36 MHD patients who were indwelled with dual-lumen catheter with a Dacron cuff for over 3 months in hemodialysis center in our hospital were selected.By random lot-drawing,they were evenly divided into observation group(micro-pumped urokinase as a thrombolytic therapy)and control group (retained urokinase at regular time as a thrombolytic therapy),18 cases in each group In the observation group,micro-pumped urokinase(125 000 U each time)and NS(100 ml)for one continuous hour of dripping,once every two weeks,while in the control group,urokinase(125 000 U each time)and NS(12 ml)were injected into a sealed tube for thrombolytic treatment at three times,one hour once,and once every two weeks.The courses of treatment lasted for 3 months.The blood flow volume,and the changes of venous pressure and KT/V before and after therapy were observed and compared in the two groups.The cuff tube thrombosis,tube infection,and catheter dysfunction were recorded in both groups.ResultsAfter therapy,the venous pressure in the observation group was(68.0±30.5)mmHg,much lower than that in the control group [(162.0±37.5)mmHg],with a statistical difference (P＜0.05).The blood flow volume and value of KT/V in the observation group were both superior to those in the control group with statistical differences(P＜0.05).After therapy,the cuff tube thrombosis,tube infection,and obstruction of catheter sucking were all lower than those in the control group with statistical differences(P＜0.05).The incidence of hemorrhage was not displayed significance difference after therapy(P＞0.05).ConclusionRegular micro-pumped urokinase as a thrombolytic therapy can effectively maintain the function of cuff catheter,prolong the use of catheter,and improve the efficiency of dialysis,which is a safe and effective therapeutic mode.
2017 Vol. 24 (30): 46-48转51 [Abstract] ( 187 ) HTML (34 KB)  PDF  (0 KB)  ( 80 )
49 Value of enteral nutrition in the treatment of severe acute pancreatitis in ICU
GUO Lin;ZENG Jin-xiu;HU Shuo
ObjectiveTo investigate the clinical value of enteral nutrition in the treatment of severe acute pancreatitis(ICU).MethodsAnalysis of the clinical data from 40 cases of patients with severe acute pancreatitis from January 2012 to January 2017 in ICU ward of our hospital were analyzed,were randomly divided into control group and experimental group,20 cases in each group.The control group was used parenteral nutrition,the experimental group received：enteral nutrition therapy,clinical curative effect between the two groups was compared.ResultsAfter the clinical treatment,the time of hospitalization,the recovery time of intestinal function and the time of mechanical ventilation treatment were all better than those of the control group,the difference was statistically significant(P＜0.05).The laboratory indexes of albumin,hemoglobin and C-reactive protein in the experimental group were significantly better than those in the control group,the differences were statistically significant(P＜0.05).ConclusionEnteral nutrition application in the clinical treatment of ICU patients with severe acute pancreatitis,contribute to the improvement of clinical symptoms,improve treatment effectiveness,so it can be used as the preferred clinical nutrition supply treatment technology,it has high application value.
2017 Vol. 24 (30): 49-51 [Abstract] ( 146 ) HTML (30 KB)  PDF  (0 KB)  ( 69 )
52 Clinical application study of modified laminectomy and selective extended decompression plus internal fixation in the treatment of multiple segmental cervical spondylosis
RAO Yi-kang;OUYANG Shao-ming;ZENG Shen-juan;ZHONG Xue-ping;GAO Yong
ObjectiveTo investigate the clinical effects of application of modified laminectomy,selective decompression and internal fixation in the treatment of patients with multiple segmental cervical spondylosis.MethodsAltogether 84 patients with multiple segmental cervical spondylosis who were treated in our hospital from February 2015 to January 2017 were selected and randomly divided into the control group and the observation group,with 42 cases in each group.The control group was treated with conventional laminectomy decompression and internal fixation,while,the observation group was treated with single-door improved laminectomy and selective decompression combined with internal fixation of the pedicle screw system.The neurological functions,the improvement of cervical functions and the incidence of complications were compared between the two groups.ResultsThe JOA score,NDI score and cervical mobility of the two groups after operation were better than those before operation,the JOA score,NDI score and cervical mobility of the observation group after operation were significantly better than those of the control group,with significant difference (P＜0.05).The incidence of postoperative back pain and C5nerve root paralysis in the observation group was significantly lower than that in the control group,with significant difference(P＜0.05).ConclusionApplication of modified laminectomy,selective decompression combined with internal fixation in the treatment of multiple segmental cervical spondylosis can significantly restore patients′nerve functions and cervical functions,which promotes the improvement of cervical vertebra activity and actively inhibits the complications.
2017 Vol. 24 (30): 52-54 [Abstract] ( 140 ) HTML (30 KB)  PDF  (0 KB)  ( 37 )
55 Clinical effects analysis of traditional Chinese medicine comprehensive rehabilitation therapy on joint function recovery of distal radius fracture in patients after treatment
WAN Zhong;WAN Chang-hao
ObjectiveTo evaluate the clinical effects of traditional Chinese medicine comprehensive rehabilitation therapy on joint function recovery of distal radius fracture in patients after treatment.Methods83 patients with distal radius fracture in our hospital from August 2015 to September 2016 were selected as the research objects.According to method of random number table,those patients were divided into the control group (n=42)and the treatment group (n=41).The control group was given traditional Chinese medicine and functional training,while the treatment group was given traditional Chinese medicine comprehensive rehabilitation therapy,treatment for 3 weeks.Side grip strength,wrist joint patients self-rating scale,Gartland and Werley (G-W)wrist joint evaluation and curative effect were compared between the two groups,the data were collected before the treatment,3 weeks after treatment,and 3 months after treatment.ResultsAfter 3 weeks treatment and 3 months after treatment,the Gartland and Werley (G-W)wrist joint evaluation and curative effect of the treatment group were significantly better than those in the control group (P＜0.05).After 3 weeks treatment,the side grip strength of the treatment group was significantly better than that of the control group (P＜0.05).After 3 months treatment,there was no statistically significant difference between the treatment group and control group in the side grip strength (P＞0.05).ConclusionThe curative effect of traditional Chinese medicine comprehensive rehabilitation therapy is better than that of the traditional Chinese medicine and functional training significantly,which is worthy of clinical promotion.
2017 Vol. 24 (30): 55-57 [Abstract] ( 170 ) HTML (36 KB)  PDF  (0 KB)  ( 68 )
58 Anesthetic effects of Ropivacaine at different concentrations by subarachnoid block applied to cesarean section
ZHONG Yu-ting;LIN Yue-hua

ObjectiveTo explore the anesthetic effect of Ropivacaine at different concentrations by subarachnoid block in cesarean section.MethodsFrom January 2016 to February 2017,120 pregnant women undergone cesarean section were enrolled as research objects.According to the different therapeutic methods,the patients were evenly divided into high concentration group(0.5%)and low concentration group(0.375%),60 cases in each group.In the high concentration group,Ropivacaine in a high concentration via subarachnoid block was used,while in the low concentration group,a low concentration Ropivacaine via subarachnoid block was adopted.The anesthetic effect,the onset time and sustained time of motor block,the onset time and sustained time of sensory block,and incidence of adverse reaction in the two groups were compared.ResultsThe anesthetic effects were compared between the two groups,the differences were not significant(P＞0.05).The the onset time of motor block and sensory block were compared between the two groups,the differences were not significant(P＞0.05).However,the sustained time of motor block and sensory block in the low concentration group was shorter than those in the high concentration group,the differences were statistically significant(P＜0.05).The incidence of adverse reactions in the low concentration group was less than that in the high concentration group,the difference was statistically significant(P＜0.05).ConclusionThere is no significant difference in the anesthetic effect between low and high concentrations of Ropivacaine in the treatment of cesarean section by subarachnoid block.Although the sustained time of block is short,the adverse reactions are few and the safety is high,which is worthy of promotion.
2017 Vol. 24 (30): 58-60 [Abstract] ( 170 ) HTML (31 KB)  PDF  (0 KB)  ( 69 )
61 Application effect of rapid rehabilitation surgery concept in anesthesia management of laparoscopic rectal cancer
WU Zhi-guo
ObjectiveTo investigate the application effect of rapid rehabilitation surgery concept in the anesthesia management of laparoscopic rectal cancer.MethodsA total of 94 patients with laparoscopic radical rectal cancer under general anesthesia who treated in our hospital from January 2015 to June 2016 were selected as the study subjects.The patients were randomly divided into rehabilitation group (47 cases)and control group (47 cases).Rehabilitation group was given anesthesia measures guided by rapid rehabilitation surgery concept,and the control group was given conventional anesthesia measures.Anesthesia recovery,incidence rate of complications and the level of serum CRP were compared between the two groups after surgery.ResultsThe postoperative recovery time,extubation time and anal exhaust and defecation time in the rehabilitation group were shorter than those in the control group,the differences were statistically significant(P＜0.01).The VAS pain score and the levels of serum CRP after surgery and on the first day after surgery in the rehabilitation group were lower than those in the control group,the differences were statistically significant(P＜0.01).The incidence rate of complications in the rehabilitation group(8.51%)was lower than that in the control group (25.53%),the difference was statistically significant(P＜0.05).ConclusionThe concept of rapid rehabilitation is safe and effective in the anesthesia management of laparoscopic rectal cancer surgery,so that patients are able to wake early after surgery and extubation is faster.The incidence of stress response and the incidence rate of complications are reduced.The clinical application value is high,and it is worthy of popularization and application.
2017 Vol. 24 (30): 61-63 [Abstract] ( 178 ) HTML (30 KB)  PDF  (0 KB)  ( 63 )
64 The application value of CTA imaging in the risk assessment of cystic intracranial aneurysm rupture
ZHOU Jian;WEI Jiang-ping; YU Ju-hong;LI Zi-cong
ObjectiveTo analyze the application value of CTA imaging in the risk assessment of cystic intracranial aneurysm rupture.MethodsFrom January 2012 to December 2015,200 patients with cystic aneurysms were enrolled as research objects.According to rupture of aneurysms,they were divided into rupture group(n＝97)and non-rupture group(n＝103).The CTA technique was used to detect the length of aneurysm and width of aneurysm neck,AR value,etc.The condition of ascus was observed and the correlation of CTA inspection result and IA rupture was analyzed.ResultsIn the rupture group,the length of aneurysm and width of aneurysm neck,AR,SR,and aneurysm tilt angle were all significantly higher than those in the non-rupture group(P＜0.05).In the rupture group,44 cases were occurred with ascus and the incidence was 45.36%,while in the non-rupture group,14 ones were occurred with ascus and the rate was 13.59%.The incidence of ascus in the rupture group was higher than that in the control group(P＜0.05).ConclusionThe rupture of intracranial aneurysms is related with the length of aneurysm,the width of aneurysm neck,AR value,SR value,aneurysm tilt angle,and the condition of ascus.Longer in the aneurysm,wider in the aneurysm neck,and the occurrence of ascus all will increase the risk of rupture,to which should be pain great attention in clinic.
2017 Vol. 24 (30): 64-66 [Abstract] ( 173 ) HTML (31 KB)  PDF  (0 KB)  ( 85 )
67 Effectiveness of application of lower limb color Doppler ultrasound combined with ankle brachial index in early diagnosis of lower extremity vascular disease in elderly patients
LUO Li-hua;LONG Zheng-xi
ObjectiveTo explore the effectiveness of application of color Doppler ultrasound combined with ankle brachial index (ABI)in the diagnosis of lower extremity vascular diseases in elderly patients,so as to provide reference for clinical diagnosis.MethodsAltogether 60 cases of elderly patients with lower extremity vascular disease who were treated in our hospital from January 2016 to March 2017 and 45 healthy cases who were underwent health examinations during the same period of time were selected as the object of this research;ultrasonic inspection with color Doppler ultrasonic diagnostic apparatus and ABI measurement with full-automatic arteriosclerosis detector were performed for all the subjects;the color Doppler ultrasound examination and ABI measurement results and peripheral arterial disease(PAD)detection rate acquired by using different methods were compared between two groups of patients.ResultsThe rough intima,IMT (Intima-Media Thickness)thickening,plaque formation,blood filling defect,lumen stenosis and lumen occlusion of the observation group examined by using ultrasound were significantly higher than those of control group,with statistically significant difference (P＜0.05);the detection rate of patients with ABI≤0.9 of the observation group was significantly higher than that of control group;and the detection rate of patients with 0.9＜ABI≤1.3 of the observation group was significantly lower than that of control group,with statistically significant difference (P＜0.05);the detection rate of PAD by using the combination of color Doppler ultrasound and ABI measurement was 88.3%(53/60),significantly higher than that of single color Doppler ultrasound examination (66.7%,40/60)and single ABI(41.7%,25/60),with statistically significant difference(P＜0.05).ConclusionApplication of color Doppler ultrasound combined with ankle brachial index in the diagnosis of lower extremity vascular disease in elderly patients is helpful for the accurate diagnosis of lower extremity vascular disease,which is worthy of clinical application.
2017 Vol. 24 (30): 67-69 [Abstract] ( 135 ) HTML (32 KB)  PDF  (0 KB)  ( 63 )
70 Application value of mammography and color Doppler ultrasonography combined with MRI for early diagnosis of breast cancer
WEI Cai-qin;JIANG Li-sha
ObjectiveTo address the application value of mammography and color Doppler ultrasonography(CDU)combined with MRI for early diagnosis of breast cancer.Methods120 patients with early breast cancer admitted to our hospital from January 2015 to March 2017 were selected as the study subjects;all the patients had been confirmed by postoperative pathology and had received：mammography,CUD and MRI preoperatively;the preoperative examination results and postoperative pathological findings were analyzed comparatively.ResultsAmong the 120 patients,106 had infiltrating duct carcinoma,3 had intraductal carcinoma,6 had infiltrating lobular carcinoma,3 had mucinous adenocarcinoma,and 2 had medullary carcinoma.100 patients were detected with mammography,accounting for the diagnose accordance rate of 83.3%;96 patients were detected by CDU,accounting for the diagnose accordance rate of 80.0%;102 patients were detected by MRI,accounting for the diagnose accordance rate of 85.0%;116 patients were detected by mammography and CDU combined with MRI,accounting for the diagnose accordance rate of 96.7%.The diagnosis accordance rate was higher with the combination of the 3 examinations than with any single examination(P＜0.05).ConclusionMammography and CDU combined with MRI could significantly improve the diagnosis rate of early breast cancer,supporting its further clinical application.
2017 Vol. 24 (30): 70-72 [Abstract] ( 170 ) HTML (31 KB)  PDF  (0 KB)  ( 67 )
73 Diagnostic value of transcranial Doppler ultrasound in middle cerebral artery stenosis
HHUANG Ying;LI Bin;LIANG Xiang-xin
ObjectiveTo investigate the value of transcranial Doppler ultrasound in the diagnosis of middle cerebral artery stenosis.Methods30 patients with middle cerebral artery stenosis diagnosed by transcranial digital subtraction angiography from June 2014 to March in 2017 were selected as research objects.Before surgery,they were all examined by transcranial Doppler ultrasound.The accuracy of diagnostic results,pulsatility index of middle cerebral artery,mean blood flow velocity and systolic velocity in patients with different stenosis were observed.ResultsBy Doppler ultrasound examination,the diagnosis of mild stenosis of middle cerebral artery in 15 cases(50.00%),moderate stenosis in 10 cases(33.33%),and severe stenosis in 5 cases(16.67%)were not displayed great difference with transcranial digital subtraction(P＞0.05).There were statistical differences in mean blood flow velocity and systolic velocity in patients with mild,moderate,and severe stenosis of middle cerebral artery(P＜0.05).ConclusionTranscranial Doppler ultrasound is of high value in the diagnosis of middle cerebral artery stenosis.
2017 Vol. 24 (30): 73-75 [Abstract] ( 152 ) HTML (31 KB)  PDF  (0 KB)  ( 77 )
76 Observation the clinical effect of Mifepristone combined with Misoprostol in induction of labor in the middle trimester of scar uterus
AI Dan;ZHONG Li-zhen
ObjectiveTo investigate the clinical effect of Mifepristone combined with Misoprostol in induction of labor in the middle trimester of scar uterus.Methods100 induction of labor in the second trimester of scar uterus patients from May 2015 to May 2016 treated in our hospital were selected as objects.Patients were divided into two groups according to lottery method,and each group was 50 cases.The control group and observation group were respectively given treatment of abdominal wall with amniotic Membrane Injection and Mifepristone combined with Misoprostol.Two groups of patients with complications,placental residual rate,bleeding volume,successful rate of induced labor,duration of medication to contractions start time,the contractions to the fetal placental delivery time,delivery time to the fetal placenta were compared.ResultsObservation group of patients with duration of medication to contractions start time [(27.69±3.52)h],the contractions to the fetal placental delivery time[(8.52±1.44)h],delivery time to the fetal placenta[(34.53±3.95)h]were shorter than those in the control group[(35.86±5.86)h,(11.32±2.56)h,(48.91±5.22)h],the differences were statistically significant(P＜0.05).Placental retention rate of the patients in observation group(4.00%)was lower than the control group(30.00%),the bleeding volume of the patients in observation group[(142.74±25.98)ml]was less than the control group [(159.86±36.85)ml],the success rate of induced labor (98.00%)was higher than the control group(76.00%),the differences were statistical significance(P＜0.05).The incidence of complications in the observation group(2.00%)was lower than the control group(26.00%),and the difference was statistically significant(P＜0.05).ConclusionMifepristone combined with Misoprostol in the treatment of induced abortion in the middle trimester of scar uterus can improve the success rate of induced labor and reduce the risk of treatment.
2017 Vol. 24 (30): 76-78 [Abstract] ( 154 ) HTML (32 KB)  PDF  (0 KB)  ( 47 )
79 Analysis of effect of pharmaceutical intervention on the use of Alanyl-glutamine in patients with tumor
LIN Yan;WU Kun-sheng;QIU Yong-jun;ZHU Min-fang;LI Ke
ObjectiveTo investigate the effect of pharmaceutical intervention on the use of Alanyl-glutamine in patients with tumor.MethodsFrom 2016 to 2017,a total of 904 patients with tumor were treated with Alanyl-glutamine in our hospital were selected as the research objects.662 cases of hospitalized patients with tumor in 2016 were selected as before intervention group,242 patients with inpatient tumors treated with Alanyl-glutamine were treated as after intervention group in the course of the pharmaceutical intervention in 2017.The case data before and after the intervention were collected,and the rationality of the clinical use of Alanyl-glutamine before and after the intervention were compared.ResultsAfter intervention,the average treatment course of Alanyl-glutamine in patients with tumor was shorter than before intervention,and the difference was statistically significant(P＜0.01).After intervention,the rate of unreasonable drug use was significantly less than before intervention,and the difference was statistically significant(P＜0.01).After intervention,the unadjusted rate of medication beyond the indication,preparation of high-concentration medication and overlong course of medication treatment after the intervention were lower than before the intervention,and the differences were statistically significant(P＜0.01).ConclusionApplication of pharmaceutical intervention in the use of Alanyl-glutamine in patients with tumor makes the clinical medication standard and reasonable,indicating that pharmaceutical intervention is feasible and effective.
2017 Vol. 24 (30): 79-82 [Abstract] ( 145 ) HTML (38 KB)  PDF  (0 KB)  ( 59 )
83 Study on the therapeutic effect of Spironolactone and Torasemide in patients with chronic pulmonary heart disease
ZENG Xing-du;WU Guo-bin
ObjectiveTo investigate the clinical effect of Spironolactone and Torasemide in patients with chronic pulmonary heart disease.MethodsA total of 72 patients with chronic pulmonary heart disease who treated in our hospital from June 2015 to December 2016 were selected as objects and were randomly divided into control group and observation group according to the random number table method.There were 36 patients in each group.The control group was treated with Tonic and Diuretic and other conventional methods.The observation group was treated with Spironolactone and Torasemide on the basis of the control group.The clinical curative effect and cardiac function were compared between the two groups.ResultsThe total effective rate in the observation group was 97.22%and 83.33%in the control group,the difference was statistically significant(P＜0.05).Before treatment and after treatment,the cardiac function grading of the two groups was compared,the differences were not statistically significant(P＞0.05).After treatment,the patients ofⅡ level in the control group was more than before treatment,the patients ofⅣ level was less than before treatment,the difference was statistically significant(P＜0.05).After treatment,the patients ofⅡ level in the observation group was more than before treatment,the patients ofⅢandⅣlevel were less than before treatment,the difference was statistically significant (P＜0.05).ConclusionThe treatment of patients with chronic pulmonary heart disease by using Spironolactone and Tolosemide on the basis of the use of Tonic and Diuretics can effectively improve the patients′cardiac function,reduce the grade of cardiac function and improve the therapeutic effect.
2017 Vol. 24 (30): 83-85 [Abstract] ( 177 ) HTML (32 KB)  PDF  (0 KB)  ( 67 )
86 Clinical effect of Clopidogrel combined with Ligustrazine Injection in the treatment of acute cerebral infarction and its influence on hemorheology
ZHOU Ying-feng
ObjectiveTo investigate the clinical effects of Clopidogrel combined with Ligustrazine Injection in the treatment of acute cerebral infarction and its influence on hemorheology.Methods118 cases of patients with acute cerebral infarction who treated in our hospital from April 2014 to December 2016 were selected as the research objects,and were divided into the control group of 62 cases and the observation group of 56 cases according to the medication regimen.The control group were treated with Clopidogrel on the basis of conventional treatment,while the observation group were treated with Ligustrazine Injection on the basis of treatment in the control group.Then,the clinical efficacy and hemorheology of two groups of patients after the treatment were observed and compared.ResultsThe total effective rate in the observation group(91.07%)was higher than that in the control group(79.03%),and the difference was statistically significant(P＜0.05).Before the treatment,there was no significant difference in the hemorheological indexes between the two groups(P＞0.05).After the treatment,the hemorheological indexes of the two groups were lower than before treatment,the observation group was lower than the control group,the differences were statistically significant(P＜0.05).ConclusionThe Clopidogrel combined with Ligustrazine Injection which can improve the clinical efficacy of acute cerebral infarction,but also can improve the hemorheological indexes,thus it is worthy to be promoted in the clinical.
2017 Vol. 24 (30): 86-88 [Abstract] ( 146 ) HTML (31 KB)  PDF  (0 KB)  ( 62 )
89 Effect observation of Irbesartan combined with Huangkui Capsule on treating chronic glomerulonephritis
JIN Bi-hui;YANG Li-hong
ObjectiveTo investigate the efficacy of Irbesartan combined with Huangkui Capsule in the treatment of chronic glomerulonephritis.MethodsFrom January 2016 to January 2017,40 patients with chronic glomerulonephritis treated in our hospital were selected as objects.According to the different therapeutic methods,they were divided into control group and observation group,20 cases in esch group.In the control group,patients were treated with Irbesartan only,while in the observation group,Huangkui Capsule was added.The clinical efficacy in the two groups was compared.ResultsBefore treatment,there was no significant difference in 24-hour proteinuria or serum creatinine(P＞0.05).After treatment,in the observation group[(0.82±0.24)g,(80.01±8.03)μmol/L]were lower than the observation group[(1.02±0.32)g,(83.52±10.11)μmol/L],and the differences were statistically significant(P＜0.05).After treatment,the 24-hour proteinuria and serum creatinine levels were lower than before treatment,and the differences were statistically significant(P＜0.05).The total effective treatment rate in the observation group (90.0%)was higher than that in the control group(70.0%),and the difference was statistically significant(P＜0.05).There was no significant difference in adverse reactions between the two groups (P＞0.05).ConclusionIrbesartan combined with Huangkui Capsule can obtain a great effect on treating chronic glomerulonephritis,which is worthy of clinical application and promotion.
2017 Vol. 24 (30): 89-91 [Abstract] ( 131 ) HTML (32 KB)  PDF  (0 KB)  ( 70 )
92 Effect observation of Metformin combined with Clomiphene in treatment of polycystic ovarian syndrome
HE Jie;SHU Ru-ming▲
ObjectiveTo investigate the therapeutic effect of Metformin combined with Clomiphene on polycystic ovary syndrome.Methods116 patients with polycystic ovarian syndrome treated in our hospital from March 2015 to January 2017 were selected as objects and were randomly divided into the observation group and the control group,58 in each group.The control group was given Clomiphene treatment,observation group on the basis of the combination of Metformin.The two groups of patients with hormone,degree of change,endometrial thickness level of ovulation rate and pregnancy rate and the incidence of adverse drug reactions were compared.ResultsAfter 3 courses of treatment,in the observation group,the changes of FINS,T,FSH,LH,endometrial thickness were better than those in the control group,the differences were statistically significant (P＜0.05).The observation group ovulation rate (72.41%),the pregnancy rate(39.66%)were higher than those of the control group,the differences were statistically significant(P＜0.05).The observation group occurred in 9 cases of adverse drug reactions,while in the control group of 7 cases,the difference was not statistically significant(P＞0.05).ConclusionThe combination of Metformin and Clomiphene on polycystic ovarian syndrome comprehensive clinical effect is good,can improve the ovulation rate and pregnancy rate,safe and effective,worthy of further clinical application.
2017 Vol. 24 (30): 92-94 [Abstract] ( 128 ) HTML (31 KB)  PDF  (0 KB)  ( 72 )
95 Clinical effect analysis of Febuxostat in the treatment of gout combined with hyperlipidemia
HUANG Hui-ping;HUANG Miao-fang
ObjectiveTo investigate the clinical effect of Febuxostat in the treatment of gout combined with hyperlipidemia.MethodsFrom August 2015 to March 2017,clinical data from 88 gout patients with hyperlipidemia treated in our hospital were selected as objects.They were evenly divided into two groups based on odd or even number,44 cases in each group.In control group Allopurinol was used,while in experimental group Febuxostat was adopted.The levels of blood lipid and blood uric acid,the occurrence of gout and incidence of adverse reactions in the two groups were compared and observed.ResultsBefore treatment,there was no significant difference in blood lipid level or blood uric acid between the two groups(P＞0.05).After therapy,the two indicators mentioned above in the experimental group were lower than those in the control group,the differences were statistically significant(P＜0.05).The incidence of gout and adverse reactions in both groups were compared,the differences were not statistically significant(P＞0.05).ConclusionCompared with Allopurinol,application of Febuxostat in the treatment of gout patients with hyperlipidemia,though similar incidence of adverse reations by the two methods,the effect to decrease the blood lipid level is more remarkable,which can decrease the levels of triglycerides,low-density lipoprotein,and serum total cholesterol.
2017 Vol. 24 (30): 95-97 [Abstract] ( 154 ) HTML (32 KB)  PDF  (0 KB)  ( 63 )
98 Effect of Leuprorelin and Goserelin on recurrence and pregnancy rates after ovarian endometriosis operation
FAN Lian-yun;WAN Gui-ping
ObjectiveTo investigate the effect of Leuprorelin and Goserelin on recurrence and pregnancy rates after ovarian endometriosis laparoscopic surgery.MethodsA total of 71 cases female patients with ovarian endometriosis,fertility intention and received conservative operation who treated in our hospital from June 2012 to June 2016 were retrospectively analyzed.According to the medication they received,patients were divided into three groups,including group NON(no medication,n＝26),group LEU(Leuprorelin,3.75 mg/28d,n＝24),and group GOS(Goserelin,3.6 mg/28d,n＝21).The clinical efficacy,recurrence rates after treatment,rates of successful pregnancy,alleviated rates of dysmenorrhea and incidence of adverse reaction of each group were compared.ResultsThe clinical efficiency of group NON (61.5%)was significantly lower than group LEU(70.8%)and group GOS(76.2%),and the differences were statistically significant(P＜0.05).The clinical efficiency of group LEU were compared with group GOS,and the difference was not statistically significant(P＞0.05).The successful pregnancy rate(38.5%),dysmenorrhea alleviated rate(65.3%)of group NON were significantly lower than that of group LEU(70.8%,75.0%)and group GOS(76.2%,76.2%),the differences were statistically significant(P＜0.05).The recurrence rates of group NON(46.2%)was significantly higher than group LEU(25.0%)and group GOS(28.6%),the differences were statistically significant(P＜0.05).The recurrence rate,successful pregnancy rate,dysmenorrhea alleviated rate and incidence of adverse reactions of group LEU were compared with group GOS,and the difference was not statistically significant(P＞0.05).ConclusionFor patients with ovarian endometriosis,conservative operation combined with administration of GnRH-a would effectively increase the clinical efficacy and rates of successful pregnancy after treatment,alleviate symptom of dysmenorrhea,reduce the recurrence rates and incidence of adverse reactions.While the differences between Leuprorelin and Goserelin have no statistically significant.
2017 Vol. 24 (30): 98-101 [Abstract] ( 158 ) HTML (36 KB)  PDF  (0 KB)  ( 74 )
102 Observation the clinical effect of Lidocaine combined with Nitroglycerin in the prevention of radial artery spasm
XU Jin;YE Fei;JIANG Yong
ObjectiveTo investigate the clinical effect of Lidocaine combined with Nitroglycerin in the prevention of radial artery spasm.Methods77 patients with transradial coronary angiography from January to August 2017 treated in our hodpital were selected as study objects.They were divided into control group(38 cases)and test group(39 cases)by single and even number grouping method.Control group was treated with 200 μg Nitroglycerin alone,and the test group was treated with 20 mg Lidocaine combined with 200 μg Nitroglycerin.The incidence rate of radial artery spasm,puncture success rate,puncture frequency,operation success rate and pain degree(VAS)score of two groups were compared and analyzed.ResultsThe incidence of radial artery spasm in the test group (0.00%)was lower than that in the control group(13.16%),the difference was statistically significant(P＜0.05).The puncture success rate(97.44%),puncture frequency[(1.05±0.36)times],operation success rate (89.74%)in the test group were lower than those in the control group [73.68%,(2.15±0.34)times,68.42%],the differences were statistically significant(P＜0.05).The VAS score in the test group[(3.56±0.54)points]was significantly lower than that in the control group[(5.64±0.24)points],and the difference was statistically significant(P＜0.05).ConclusionLidocaine combined with Nitroglycerin can reduce the incidence of radial artery spasm in patients with CAG,with high success rate of puncture and the pain is low.It is worthy of clinical application.
2017 Vol. 24 (30): 102-104 [Abstract] ( 123 ) HTML (30 KB)  PDF  (0 KB)  ( 83 )
105 Clinical observation of meridian tropism syndrome differentiation in the treatment of intractable facial paralysis
SHEN Jin-huan
ObjectiveTo observe the clinical efficacy of meridian scraping therapy in the treatment of intractable facial paralysis.Methods36 patients with intractable facial paralysis treated in department of acupuncture and moxibustion of our hospital from June 2016 to April 2017 were selected as the object of this study and divided into observation group and control group according to the treatment methods,and there were 18 cases in each group.The observation group was treated with common acupuncture and meridian scraping therapy,while the control group was treated with common acupuncture and scraping therapy.10 days were a course of treatment.After 3 courses of treatment,the pre-and posttreatment House-Brackmann (H-B)facial nerve function grading and clinical curative effect in patients of two groups were evaluated.ResultsThe post-treatment level of H-B facial nerve function grading in two groups was better than that before treatment respectively,and the level of H-B facial nerve function grading of the observation group was significantly better than that of control group (P＜0.05).The total effective rate of the observation group was 88.89%,which was significantly higher than that of the control group(77.78%),with statistically significant difference(P＜0.05).ConclusionMeridian scraping therapy is effective for intractable facial paralysis and deserves to be popularized.
2017 Vol. 24 (30): 105-107 [Abstract] ( 112 ) HTML (31 KB)  PDF  (0 KB)  ( 43 )
108 Clinical effect analysis of traditional Chinese medicine acupuncture combined with massage in treatment of cervical spondylosis of vertebral artery type
WEI Li-li;CAO Jun-yong
ObjectiveTo study the clinical effect of traditional Chinese medicine acupuncture combined with massage in treatment of cervical spondylosis of vertebral artery type.Methods82 patients with cervical spondylosis of vertebral artery type treated in our hospital and Nanchang Massage Hospital from March 2015 to March 2017 were selected and they were randomly divided into the treatment group(n＝41)and the control group(n＝41).The control group was treated with traditional Chinese medicine acupuncture only while the treatment group was treated with traditional Chinese medicine acupuncture combined with massage.The disappear time of cervical spondylosis symptoms,total treatment time,the time of returning to normal for cervical physiological function,the total effective rate,adverse reactions during treatment and improvement of clinical symptom score before and after treatment in patients between the two groups were compared.ResultsThe disappear time of cervical spondylosis symptoms,total treatment time,the time of returning to normal for cervical physiological function in the treatment group were shorter than those of control group,and there was a statistical difference (P＜0.05).The total effective rate of the treatment group was 90.3%,which was higher than that of the control group(68.3%),and there was a statistical difference(P＜0.05).The incidence of adverse reactions in the treatment group was 2.4%,which was lower than that of the control group(19.5%),and there was a statistical difference(P＜0.05).The improvement of clinical symptom score before and after treatment in the treatment group was larger than that of the control group,and there was a statistical difference(P＜0.05).ConclusionTraditional Chinese medicine acupuncture combined with massage in treatment of cervical spondylosis of vertebral artery type can quickly improve the function of cervical vertebra,reduce the adverse reaction and improve the therapeutic effect.
2017 Vol. 24 (30): 108-110 [Abstract] ( 136 ) HTML (37 KB)  PDF  (0 KB)  ( 72 )
111 The influence of auricular point pressing therapy on the life and sleeping quality of patients with stroke
HOU Jing;HU Li-juan; XIE Yan
ObjectiveTo discuss the effect of auricular point pressing therapy treating stroke and its influence on the life and sleeping quality of patients.Methods90 patients with stroke hospitalized in our hospital from February 2014 to March 2017 were admitted into research and they were grouped according to the random number table method.Control group(n＝45)was given the routine nursing while observation group was combined with auricular point pressing therapy.One month was a course of treatment.The improvement of life quality and Pittsburgh sleep quality index(PSQI)and the total nursing satisfaction degree in patients between the two groups were compared.ResultsAfter intervention,physical function,emotional function,psychological function,social function dimension score was increased,PSQI index in patients between the two groups was decreased,and the difference was statistically significant(P＜0.05).After intervention,various dimension score of life quality in the observation group was higher than that of control group,PSQI index was lower than that of the control group (P＜0.05).The total satisfaction degree of the observation group was 95.56%,which was higher than that of the control group(77.78%),and the difference was statistically significant(P＜0.05).ConclusionFor patients with stroke,auricular point pressing therapy applied has a significant significance,and it can better improve the life and sleep quality,and help to promote the harmony between nurses and patients,it is worth promoting.
2017 Vol. 24 (30): 111-113 [Abstract] ( 163 ) HTML (32 KB)  PDF  (0 KB)  ( 90 )
114 Influence analysis of acupoint massage during perinatal period on postpartum lactation in cesarean section puerpera
WANG Juan
ObjectiveTo observe the influence analysis of acupoint massage during perinatal period on postpartum lactation in cesarean section puerpera.Methods120 cesarean section puerperae treated in our hospital from January 2015 to December 2016 were selected and they were divided into the observation group and control group,and there were 60 cases in each group.The two groups were given the routine health education and postnatal nursing,while the observation group was given acupoint massage on the basis of the control group.The initial time of lactation,lactation amount and serum prolactin level of two groups was observed respectively.ResultsThe proportion of colostrum secretion in 24 h in puerpera of the observation group was 46.67%,which was significantly higher than that of the control group (16.67%)(P＜0.05).Lactation amount in puerpera of the observation group was significantly better than of the control group (P＜0.05).After treatment,the serum prolactin level in the observation group was(27.30±2.45)ng/ml,which was significantly higher than that of the control group [(20.12±2.13)ng/ml],and there was a statistical difference (P＜0.05).ConclusionAcupoint massage can shorten the initial time of lactation,increase the lactation amount and the serum prolactin level.
2017 Vol. 24 (30): 114-116 [Abstract] ( 128 ) HTML (34 KB)  PDF  (0 KB)  ( 71 )
117 Experimental study on the effect of Silybin on skin quality of nude mice
WANG Xue;FU Wei;YANG Liu;LI Jian-min; XU Yan-ming
ObjectiveTo study the influence of Silybin cream on skin damage of nude mice model induced by UVB,including skin moisture,pH value,melanin and heme.Methods40 nude mice were divided into 4 group,they were the blank group,the model group,the positive control group and the Silybin group.The blank group was given a touch every day,and the model group was given UVB exposure every day after touching.Nude mice′s back in the positive control group and the Silybin group was smeared by Shiseido yurao zhenlai and Silybin cream before irradiated by UVB,nude mice in the model group,the positive control group and the silybin group were irradiated by UVB for 15 days continually,each time 20 min,the back of nude mice was damaged,the back was tested by the skin tester produced by German CK company after irradiating.ResultsThe moisture content in the model group decreased distinctively compared with the blank group,pH value increased,melanin and heme content increased,with significant difference(P＜0.05).The moisture content in the positive control group and the Silybin group increased compared with the blank group and the model group,pH value decreased,melanin and heme content decreased,with significant difference(P＜0.05).ConclusionSilybin can increase skin moisture,decrease hyper pigmentation,reduce skin damaged by outside stimulus,and repair damaged skin effectively.
2017 Vol. 24 (30): 117-119 [Abstract] ( 136 ) HTML (35 KB)  PDF  (0 KB)  ( 39 )
120 Relationship between the expression of LASS2 and Ki67 with recurrent of nasopharyngeal carcinoma and its significance
WANG Jian-zhang;HE Zhi-ming;HUANG Jin-fen;LI Wei-xia
ObjectiveTo investigate the relationship between LASS2 and Ki67 expression with the recurrent of nasopharyngeal carcinoma(NPC)and its significance.MethodsA total of 126 cases of NPC biopsy specimens in our hospital from 2011 to 2014 were collected,including 77 initial cases and 49 recurrent cases.Immunohistochemical methods were used to detect the expression of LASS2 protein and Ki67 in 126 patients with NPC.The difference between the expression of LASS2 and Ki67 in the two groups and their correlation were analyzed.ResultsThe positive rate of LASS2 in recurrent cases was 61.2%,which was lower than 88.3%of the initial cases,with significant difference(P＜0.001).Ki67 had no significant correlation with the recurrence of NPC(P＞0.05),however,there is a negative correlation between LASS2 expression and Ki67 (P＜0.05).ConclusionLASS2 was low-expressed in the recurrence of NPC.Detection of LASS2 protein may help to prompt tumor recurrence.LASS2 may be a clinically significant biological indicator for predicting the recurrence of NPC.LASS2 is negatively correlated with Ki67.It is suggested that LASS2 may inhibit the proliferation of NPC tumor cells.
2017 Vol. 24 (30): 120-122 [Abstract] ( 164 ) HTML (31 KB)  PDF  (0 KB)  ( 58 )
123 Application of procalcitonin,C-reactive protein and mitochondrial DNA level test in the assessment of multiple organ dysfunction in elderly patients with sepsis
LIAO Xiao-long;GUO Wei-xin;WANG Zhong-hua;LIANG Jun;WANG Shou-hong
ObjectiveTo explore the application values of procalcitonin(PCT),C-reactive protein(CRP)and mitochondrial DNA(mt-DNA)level test in the assessment of multiple organ dysfunction in multiple organ dysfunction in elderly(MODSE)patients with sepsis.MethodsFrom January 2014 to December 2016,62 elderly patients with sepsis admitted into our hospital were selected as research objects.Among them,29 patients complicated with organ failure were classified into the failure group,and the rest was categorized into the non-failure group.Meanwhile,another group of 30 healthy participants after physical examinations was classified into the control group.The differences of PCT,CRP,and mt-DNA levels were compared.ResultsThe levels of PCT,CRP and mt-DNA levels in sepsis patients were significantly higher than those in the control group (P＜0.05).The levels of mt-DNA and PCT in the failure group were significantly higher than those in the non-failure group(P＜0.05).But,there was no great difference in CRP between the failure group and the non-failure group (P＞0.05).According to the conditions of organ failure,the patients were further divided into the single-organ failure group (n=11),the double-organ failure group (n=9),and the three or above organ failure group(n=9).With the increased number of failure organs,the levels of mt-DNA and PCT were greatly increased,which were displayed statistical significance between inter-group comparison(P＜0.05),the CRP level was not in a statistical difference after comparison(P＞0.05).ConclusionProcalcitonin,CRP and mt-DNA all can indicate the occurrence of sepsis in elderly patients.Test of PCT and mt-DNA levels can not only be used in the diagnosis of sepsis,but also to evaluate the MODSE patients with sepsis,which is worthy of clinical promotion and application.
2017 Vol. 24 (30): 123-125 [Abstract] ( 121 ) HTML (32 KB)  PDF  (0 KB)  ( 42 )
126 Value of plasma D-dimer and coagulation four markers in pregnancy-induced hypertension syndrome
LIANG Fu-xiao;FANG Yun-yong;WEN Hai-ping;ZENG Yue-xin
ObjectiveTo investigate the value of plasma D-dimer (D-D)and coagulation four markers in pregnant women with pregnancy-induced hypertension syndrome.MethodsA retrospective analysis was carried out on 30 cases of normal pregnant women(the normal pregnancy group),30 cases of non-pregnant women(the normal control group)and 87 cases of pregnant women who were diagnosed as pregnancy-induced hypertension syndrome(the pregnancy-induced hypertension group)in our hospital from January 2015 to June 2016.The level of prothrombin time(PT),activated partial thromboplastin time (APTT),thrombin time (TT),fibrinogen (FIB)and D-D level were compared.ResultsThe PT and APTT of the pregnancy-induced hypertension group was significantly shorter than that of the normal pregnancy group and the normal control group,and the level of FIB and D-D of the pregnancy-induced hypertension group was significantly higher than that of the normal pregnancy group and the normal control group,with significant difference(P＜0.05).The PT and APTT of the normal pregnancy group was significantly shorter than that of the normal control group,and the level of FIB and D-D of the normal pregnancy group was significantly higher than that of the the normal control group,with significant difference (P＜0.05).There was no statistical difference between the TT of the three groups (P＞0.05).ConclusionThe blood of pregnant women is in hypercoagulable state,especially in pregnancy-induced hypertension women.Therefore,the routine examination of blood coagulation and D-D contributes to the understanding the coagulation and fibrinolysis function of pregnancy-induced hypertension women.It has important clinical significance in the diagnosis,observation,treatment and prevention of complications of pregnancy-induced hypertension syndrome.
2017 Vol. 24 (30): 126-128转132 [Abstract] ( 143 ) HTML (32 KB)  PDF  (0 KB)  ( 64 )
129 Discussion on interference factors and countermeasures of drugs on common clinical test samples
ZHAO Yong-mei
ObjectiveTo investigate the interference factors and countermeasures of drugs on common clinical samples.Methods300 patients who were admitted to our hospital from January 20 in 2015 to June 20 in 2017 were selected.The basic data were retrospective analyzed.The interference caused by the drugs on the detection of clinical test samples was investigated.ResultsIn 300 patients,the blood test results were interfered by the drugs used,such as white blood cells(1.33%),hemoglobin(0.33%),platelet(1.00%),eosinophil(0.33%),coagulation factorⅡtime(0.33%),bleeding time(0.33%).The drugs used affected the results of urine tests,such as color(0.67%),density(0.33%),white blood cells(0.67%),protein(0.67%),red blood cells(0.67%),glucose(0.67%),bilirubin(1.00%),urobilinogen(1.00%).In stool test results,4 cases (1.33%)were treated with ferrous phosphate and Bismuth Aluminate Compound Tablet were found false positive results.3 cases(1.00%)were given vitamin C and the positive results of fecal occult blood test were weakened,and 2 cases (0.67%)showed false negative results.ConclusionClinically,the short-term medication in the patients should be analyzed comprehensively,to facilitate the further improvement of the accuracy of drugs on the test results of samples,so as to provide the relevant judgment basis for the diagnosis and treatment of the disease.
2017 Vol. 24 (30): 129-132 [Abstract] ( 135 ) HTML (32 KB)  PDF  (0 KB)  ( 64 )
133 Effect of combined detection of D-dimer and Fg in the early diagnosis of coronary heart disease
WANG Gui-ping
ObjectiveTo investigate the effect of D-dimer(D-D)combined with fibrinogen(Fg)in the early diagnosis of coronary heart disease.Methods362 patients who were diagnosed as coronary artery disease(stenosis≥50%)by coronary angiography from January 2014 to December 2016 were selected and divided into the single branch group,the double branch group and the multiple branch group according to the branch number of arterial stenosis.The patients were divided into the unstable angina pectoris group(the UAP group),the stable angina pectoris group(the SAP group)and the acute myocardial infarction group(the AMI group)according to the diagnostic criteria of coronary heart disease.Another 120 cases of healthy subjects with negative results of coronary angiography were selected as the control group.The level of Fg and D-D were detected and compared between each group.ResultsThe levels of Fg and D-D in patients with coronary heart disease group were higher than those in the control group,with significant difference(P＜0.05).The Fg and D-D levels in the AMI group was higher than that in the UAP group and the SAP group,with significant difference (P＜0.05).There was no significant difference in the Fg and D-D levels between the UAP group and the SAP group (P＞0.05).The level of Fg in the multiple branch group was higher than that in the double branch group and the single branch group,and level of Fg in the double branch group was higher than that in the single branch group,with significant difference(P＜0.05).There was no significant difference in D-D level between each artery disease group(P＞0.05).ConclusionD-D combined with Fg detection is beneficial to the diagnosis of early coronary heart disease,which is worthy of clinical popularization and application.
2017 Vol. 24 (30): 133-135 [Abstract] ( 142 ) HTML (32 KB)  PDF  (0 KB)  ( 54 )
136 Value of Cysc,mAlb/Cr andⅣ-C detection in the diagnosis of type 2 diabetic nephropathy
LAI Xin
ObjectiveTo investigate the value of the serum cystatin (Cysc),urinary albumin/creatinine (mAlb/Cr)and typeⅣ collagen (Ⅳ-C)in the early diagnosis of type 2 diabetic nephropathy.MethodsFrom January 2016 to January 2017,60 patients with type 2 diabetes mellitus in our hospital were selected and divided into the observation group A(microalbuminuria)and the observation group B (large proteinuria)according to the different urine protein,30 cases in each group.At the same time,30 healthy volunteers in outpatient department of our hospital were randomly selected as the control group.The level of serum Cysc was determined by enhanced turbidimetry,the mAlb value of urine was determined by immune scattering method,the urinary Cr was determined by alkaline picric acid method,theⅣ-C value was determined by ELISA method.The detection rates of Cysc,mAlb/Cr and IV-C of combined determination and single determination were recorded,The sensitivity,specificity,false positive rate and false negative rate of Cysc,mAlb/Cr andⅣ-C of combined determination and single determination were compared.ResultsThe level of Cysc,mAlb/Cr andⅣ-C of the observation group A and group B increased significantly compared with the control group,while the level of Cysc,mAlb/Cr andⅣ-C of the observation group B increased significantly compared with the observation group A (P＜0.05).Combined with the single determination,the sensitivity and specificity in the combined determination significantly increased (P＜0.05).Compared with the single index measurement,the false positive rate and the false negative rate of combined determination was significantly lower (P＜0.05).ConclusionCompared with the single determination of the three indicators,the clinical application of combined determination of Cysc,mAlb/Cr andⅣ-C index in the early diagnosis of type 2 diabetic nephropathy were significantly improved,and the accuracy and specificity were higher,with clinical application and promotion significance.
2017 Vol. 24 (30): 136-138 [Abstract] ( 134 ) HTML (36 KB)  PDF  (0 KB)  ( 39 )
139 Effect analysis of platelet antibody screening technique on differential diagnosis of idiopathic thrombocytopenic purpura and aplastic anemia
LIN Ming-xiang;HUANG Xin;CHEN Xin

ObjectiveTo analyze the application effect of platelet antibody screening technique in the differential diagnosis of idiopathic thrombocytopenic purpura (ITP)and aplastic anemia (AA).MethodsA total of 480 cases with AA,ITP patients and healthy subjects from February 2014 to August 2016 in our hospital were selected.Blood cell analyzer and platelet antibody(PA IgG)screening were used to compare the results of PA IgG in each group,and the relationship between AA and ITP and platelet transfusion refractoriness was evaluated.ResultsThe positive rate of PA IgG in the ITP group(63.0%)was higher than that in the AA group(35.7%),with significant difference(P＜0.05).The ineffective rate of platelet transfusion of PA IgG positive patients in the AA group was 71.1%,which was higher than 13.6%of negative patients,with significant difference(P＜0.05).The ineffective rate of platelet transfusion of PA IgG positive patients in the ITP group was 64.4%,which was higher than 23.0%of negative patients,with significant difference(P＜0.05).The ineffective rate of platelet transfusion in the AA group with PA IgG positive matching patients was 19.0%,which was lower than 100.0%of patients without matching type,with significant difference(P＜0.05).The ineffective rate of platelet transfusion in the ITP group with PA IgG positive matching patients was 11.1%,which was lower than 100.0%of patients without matching type,with significant difference (P＜0.05).ConclusionPlatelet matching can improve the clinical infusion effect.Platelet antibody screening can provide reference for the differential diagnosis of AA and ITP.
2017 Vol. 24 (30): 139-141 [Abstract] ( 129 ) HTML (30 KB)  PDF  (0 KB)  ( 59 )
142 Diagnosis value of combined detection of PCT,CRP and WBC in the children patients with bacterial infection
ZHANG Xiao-yan;FENG Xin-ran
ObjectiveTo investigate the diagnostic value of combined detection of PCT,CRP and WBC in children patients with bacterial infection.Methods150 patients who were admitted to our hospital due to infection from October 2014 to February 2017 were included in the study.The clinical data were retrospectively analyzed.According to the final diagnosis,the patients were divided into the virus infection group(group A),the local bacterial infection group(group B),and the severe bacterial infection group(group C).The level of serum PCT,peripheral blood leukocyte(WBC),C-reactive protein (CRP)and other indices were compared between the three groups.ResultsThe levels of PCT and CRP in group C were the highest,followed by group B and the lowest in group A,the differences were significant(P＜0.05).There was no significant difference in WBC level between group C and group B,but all higher than that in group A (P＜0.05).The sensitivity of local bacterial infection diagnosed by CRP was 74.00%in the highest(44/50),and the sensitivity of PCT to severe infection was as high as 100.00%(50/50)(P＜0.05).ConclusionPCT,CRP and WBC have important evaluation value in bacterial infection.CRP is more sensitive to local bacterial infection,PCT is the most sensitive to severe bacterial infections,and WBC has a relatively low sensitivity.
2017 Vol. 24 (30): 142-144 [Abstract] ( 117 ) HTML (30 KB)  PDF  (0 KB)  ( 70 )
145 Application of plasma homocysteine and C-reactive protein in the diagnosis of carotid atherosclerosis
GUO Yan
ObjectiveTo investigate the significance and effect of plasma homocysteine (Hcy)and C-reactive protein(CRP)in the diagnosis of carotid atherosclerosis.Methods70 patients with carotid atherosclerosis diagnosed in our hospital from January 2015 to January 2017 were selected as the observation group,at the same time,extravascular ultrasound was performed,40 patients with carotid intima-media thickness of the localized thickening but no plaque formation were selected as group A (no plaque formation),30 patients with the carotid artery intima thick diffuse thick and visible plaque formation was selected as group B.70 cases without carotid atherosclerosis in our hospital physical examination center were randomly selected as the control group.The levels of Hcy,CRP,and other biochemical markers in the observation group and the control groups were measured and compared.ResultsThere was no significant difference in the levels of serum urea nitrogen,creatinine,uric acid,fasting blood glucose,triglyceride,creatine kinase,high density lipoprotein and low density lipoprotein between the observation group and the control group(P＞0.05).The levels of Hcy and CRP in the observation group were significantly higher than those in the control group,with significant difference(P＜0.05).The levels of Hcy and CRP in group A were significantly lower than those in group B,the difference was statistically significant(P＜0.05).ConclusionPlasma Hcy and C-reactive protein can provide a diagnostic basis for the diagnosis of atherosclerosis.It is a quick and effective method,which is suggested that the examination can be popular used clinically.
2017 Vol. 24 (30): 145-147 [Abstract] ( 118 ) HTML (30 KB)  PDF  (0 KB)  ( 63 )
148 The effect of improving the operation team building to improve the medication safety of the operating room
KONG Miao-juan;HUANG Su-zhen;LUO Fu-rong
ObjectiveTo explore the effect of improving the operating room team building to improve the medication safety of the operating room.MethodsSince April 2016,our hospital began to implement the operation team building improvement project.A total of 1954 patients who underwent operating room medication before improvement(January to December 2015)and 2047 patients who underwent operating room medication after improvement(April 2016 to March 2017)were analyzed,and the medication errors,close to errors and patient injury were compared.ResultsThe numbers of medication errors,close to errors and patient injury after improvement were (2.98%,4.98%,1.03%),which were significantly lower than those before improvement(7.98%,9.77%,3.12%),the differences were statistically significant(P＜0.01).ConclusionThe improvement of the operation team can improve the medication safety of the operating room.
2017 Vol. 24 (30): 148-150转153 [Abstract] ( 122 ) HTML (28 KB)  PDF  (0 KB)  ( 62 )
151 Application effect of meticulous nursing management mode in operating room
ZHANG Chao-hong;LIN Ze-hua;PENG Jian-you
ObjectiveTo investigate the application effect of meticulous nursing management mode in operating room.MethodsFrom June to December 2016,60 patients with surgical treatment who treated in our hospital were selected as control group,and 60 patients with surgical treatment who treated in our hospital from January to June 2017 were selected as observation group.The control group was treated with routine nursing in the operation room,and the observation group was treated with meticulous nursing management on the basis of routine nursing in the operating room.The postoperative coordination degree and satisfaction degree of the two groups were compared.ResultsThe postoperative coordination degree of the observation group was 100%,which was higher than that of the control group 88.3%,the patients′satisfaction was 98.3%,which was higher than the control group (86.7%),the differences were statistical significance (P＜0.05).ConclusionThe application effect of meticulous nursing management mode in operating room is remarkable,which can improve the degree of operation coordination of patients and play a positive role in improving patients′satisfaction,which is worthy of clinical popularization.
2017 Vol. 24 (30): 151-153 [Abstract] ( 159 ) HTML (31 KB)  PDF  (0 KB)  ( 62 )
154 Case analysis of suspected pneumoconiosis in Pingxiang City in 2016
LAI Xia;SHI Yong-hui;CHEN Zhong-fu
ObjectiveTo understand the detection situation of suspected pneumoconiosis in Pingxiang City in 2016.MethodsData of suspected pneumoconiosis cases in Pingxiang City were collected and analyzed statistically in 2016.ResultsA total of 74 suspected pneumoconiosis cases were found,and 57 were diagnosed in Pingxiang City in 2016.Suspected pneumoconiosis cases were covered by multiple diseases,including coal pneumoconiosis (62.16%),potter′s pneumoconiosis(9.46%),Silicosis(25.68%),cement pneumoconiosis(2.70%)and so on,the confirmed cases were mainly coal workers′pneumoconiosis;suspected cases and confirmed cases were distributed differently in the counties,suspected cases of pneumoconiosis were concentrated in small and medium-sized private enterprises(87.84%),while the confirmed cases were concentrated in large state-owned enterprises(68.42%),most of which are mining and manufacturing industries.ConclusionPneumoconiosis in Pingxiang City is still in a high incidence in a certain period of time,the prevention and treatment of pneumoconiosis should not only focus on coal miner′s disease,but also pay attention to ceramics,cement,fireworks and other industries,especially,the intensity of prevention and control of small and medium-sized enterprises should strengthen.
2017 Vol. 24 (30): 154-156转162 [Abstract] ( 108 ) HTML (31 KB)  PDF  (0 KB)  ( 66 )
157 Safety and immunological curative effect observation of measles,mumps,and rubella combined attenuated live vaccination in children
YU Dan;WANG Jing
ObjectiveTo observe the clinical safety and immunological curative effect of measles,mumps,and rubella combined attenuated live vaccination in children.MethodsA total of 400 children who were vaccinated against measles,mumps and rubella live vaccines were randomly selected from January 2001 to December 2016 in the Center for Disease Control and Prevention of Yingtan City in Jiangxi Province.According to the vaccination grouping,100 cases of children vaccinated against live attenuated measles,100 cases of children with mumps attenuated live vaccination,100 patients were given rubella live attenuated vaccination,100 cases of children were given measles,mumps,and rubella combined attenuated live vaccination.The incidence of adverse events such as rash,fever,nausea and vomiting,anorexia and diarrhea were observed within 30 min after inoculation.Immunological evaluation was carried out by using antibody titer,and the geometric mean titer of each group was compared.ResultsThe incidence of adverse reactions after inoculation was 9.00% (9/100),compared with other groups,the difference was not statistically significant(P＞0.05).The average geometric titers of rubella after immunization in children with measles,mumps,and rubella combined attenuated live vaccination were 1∶31,and compared with the average geometric titers of rubella vaccine group(1∶29),there was significant difference (P＜0.05).There was no significant difference in the average geometric titers between measles and mumps(P＞0.05).ConclusionThe preventive effect of measles,mumps,and rubella combined attenuated live vaccination is definite,compared with single measles vaccine,mumps vaccine and rubella vaccine,there is no increase in the incidence of adverse reactions,and clinical treatment is safe and reliable,but from the point of view of immunological efficacy,measles,mumps,and rubella combined attenuated live vaccination will lead to rubella geometric mean titer rise,and must pay attention to clinical staff.
2017 Vol. 24 (30): 157-159转165 [Abstract] ( 163 ) HTML (34 KB)  PDF  (0 KB)  ( 70 )
160 Discussion on the teaching modes of clinical practice for medical international students in China
LIU Jun-ling;ZHAO Xiao-hua;LI Xue-mei;WANG Yan-qiang
In recent years,more and more international students come to China to explore medicine.Clinical practice teaching modes are discussed on how to train the clinical thinking and improve the level of clinical practice of international students in recent years in our university.A new mode of clinical practice education,“medical knowledge,clinical skills,occupation quality”is formed in the experiences of the education for international students.By increasing the teaching time of clinical practice,strengthening the chinese proficiency training of students and construction of teaching staff,developing the advantages of simulated medical teaching,forming the bilingual mode between international students and graduate students,strengthening of the training of clinical skills and professional quality training,etc.,the level of the clinical practices of international students is increased and more high-level medical international students,who adapt to the international competition,are cultivated for the international society.
2017 Vol. 24 (30): 160-162 [Abstract] ( 147 ) HTML (30 KB)  PDF  (0 KB)  ( 67 )
163 Application effect of problem-based learning combined with teaching of scenario simulation in teaching of operating room nursing
WENG Chen-ting;WAN De-hua
ObjectiveTo investigate the application effect of problem-based learning combined with teaching of scenario simulation in teaching of operating room nursing.Methods80 nursing students in operating room in our hospital in 2016 were selected as objects,and they were divided into observation group and control group by teaching methods,40 cases in each group.Control group was given traditional teaching,while observation group was given problem-based learning combined with teaching of scenario simulation.The theoretical score,actual operating score,teaching satisfaction,excellent rate of assessment were compared between the two groups.ResultsThe theoretical score,actual operating score in observation group were (94.14±5.21)points and (94.61±3.17)points,which were higher than those in control group[(88.78±1.47)points,(88.51±2.32)points],the differences were statistically significant(P＜0.05).The teaching satisfaction,excellent rate of assessment in observation group (100%,95%)were higher than those in control group (80%,75%),the differences were statistically significant(P＜0.05).ConclusionProblem-based learning combined with teaching of scenario simulation in teaching of operating room nursing has excellent application effects,it can enhance nursing ability of nursing students,increase professional self-identity,strengthen responsibility,improve theoretical score and actual operating score,increase teaching satisfaction and excellent rate of assessment,which has significant application effects.
2017 Vol. 24 (30): 163-165 [Abstract] ( 132 ) HTML (30 KB)  PDF  (0 KB)  ( 61 )
166 Study on improving the communication ability of medical students by special training of doctor patient communication
ZHANG Qi
ObjectiveTo analyze and explore the importance of communication between doctors and patients and the application effect of medical communication training to improve the communication ability of medical students.MethodsFrom July 2016 to July 2017,30 patients in our hospital and the related practice of graduate students and training doctors were selected as the observation group,the unified communication special training courses were implemented in observation group.30 medical students were selected as the control group,according to the practice of the tutorial system explain the doctor-patient communication related knowledge and skills were carried out by the instructors themselves.Medical communication awareness of two groups of medical students was evaluated and measured by means of doctorpatient communication cognitive table.The scores of each dimension and the scores of two groups were compared.ResultsThe observation group with communication initiation,information collection,information given,understanding patients,communication end and other related items scores[(21.37±4.38),(44.50±5.13),(17.89±2.62),(19.69±2.68)and(9.72±1.78)points]were significantly higher than the control group[(17.86±3.15),(39.19±5.46),(13.18±2.94),(15.13±2.89)and(7.02±1.25)points],and the differences were statistically significant(P＜0.05).ConclusionStrengthening the special training of doctor-patient communication can significantly improve the communication skills of medical students,especially in the information collection and the understanding of patients,has higher value in clinical application.
2017 Vol. 24 (30): 166-168 [Abstract] ( 114 ) HTML (30 KB)  PDF  (0 KB)  ( 63 )
169 The influence of humanistic nursing on the prognosis of patients with pelvic inflammatory in department of gynaecology
LI Dong-jiao
ObjectiveTo explore the influence of humanistic nursing on the prognosis of patients with pelvic inflammatory in department of gynaecology.MethodsFrom January 2014 to May 2017,100 patients with pelvic inflammatory treated in department of gynaecology in our hospital were selected as the research object and the patients were randomly divided into the control group (n＝50)and the observation group (n＝50)by taking the computer random number table method.The control group received routine nursing while the observation group received humanistic nursing.The treatment effect,score of life quality and the total satisfaction degree of nursing were compared between the two groups.ResultsThe total effective rate in the observation group was 96%,which was significantly higher than that(82%)of the control group(P＜0.05).The score of life quality in the physical health,mental health,material life and social function,the observation group were higher than the control group(P＜0.05).The total satisfaction degree of nursing in the observation group reached 94%,which was higher than that(78%)of the control group(P＜0.05).ConclusionThe implementation of humanistic nursing intervention during the treatment of patients with gynecological pelvic inflammatory in department of gynaecology can ensure the treatment effect,improve the life quality,and improve the prognosis.
2017 Vol. 24 (30): 169-171 [Abstract] ( 124 ) HTML (32 KB)  PDF  (0 KB)  ( 63 )
172 Clinical study of different sucking material on relieving neonatal venipuncture pain
HUA Xiang-ling
ObjectiveTo analyze the clinical effect of different sucking material on relieving neonatal venipuncture pain.MethodsFrom January 2016 to January 2017,150 preterm infants treated in our hospital were divided into three groups based on different sucking material,and there were 50 cases in each group.In group A,non-nutritive sucking was selected,while in group B,liquid milk sucking by cotton swab was chosen,in group C,water with glucose sucking by cotton swab was applied.Tshe intravenous pain relief effect among three groups was compared.ResultsIn the group A,5 minute after puncturation,the heart rate,oxygen saturation,PIPP score,and NIPS score was(168±2)times per minute,(75.6±0.7)%,(6.28±1.16)points,and(2.01±0.41)points respectively,while in group B,after 5-minute puncturation,it was(154±3)times per minute,(86.2±0.7)%,(3.15±1.05)points,and(0.85±0.12)points and in group C respectively,it was(152±3)times per minute,(86.8±0.7)%,(3.08±1.02)points,and(0.88±0.13)points respectively.The success rate of puncturation and the rate of crying on puncturation in group A was 76%and 28%respectively,and it was 96%and 10%in the group B respectively,and 96%and 8%in the group C respectively,which were displayed statistical difference after comparison between group A and group B and group C(P＜0.05).There was no great difference in indexes in group B and group C(P＞0.05).ConclusionCompared with the non-nutritive sucking,liquid milk or water with glucose sucking by cotton swab in premature infants can alleviate their pain during intravenous puncturation,and its clinical value is high.
2017 Vol. 24 (30): 172-174 [Abstract] ( 106 ) HTML (34 KB)  PDF  (0 KB)  ( 61 )
175 Clinical application of early warning score for children combined with SBAR shift exchange in pediatric ward
ZENG Shui-ying;XIAO Dong-su;DONG Xian-yan
ObjectiveTo explore the application effect of early warning score for children combined with SBAR shift in hospitalized children of pediatric ward.Methods120 pediatric patients in line with standards and hospitalized in pediatric ward of our hospital from June 2016 to May 2017 were selected.According to the order of admission to the hospital,they were divided into the study group (n＝60,given regular diagnosis treatment+early warning score for children+SBAR shift exchange)and control group(only regular treatment)in random.The hospital stay,the occurrence of shift exchange problems,and the family satisfaction degree were compared between the two groups.Fifty doctors were randomly investigated during the intervention of the two groups for their job satisfaction degree in pediatric department.ResultsIn the study group,the family satisfaction degree and doctor′s satisfaction degree was 98.3%,96.0%respectively,which was higher than that of the control group (86.7%,80.0%respectively,which were displayed statistical differences(P＜0.05).In the study group,the hospital stay was shorter in comparison with that in the control group with a statistical difference (P＜0.05).The incidence of shift exchange problems in the study group was lower than that in the control group with a statistical difference(P＜0.05).In the study group,the non-planned occupancy rate of PICU,the rate of discharging without medical advice,and mortality were all lower than those in the control group,which were displayed statistical differences (P＜0.05).ConclusionIn the management of pediatric wards,application of early warning score for children combined with SBAR shift mode can improve family and doctor satisfaction degree,shorten the hospital stay,reduce the occurrence of shift problems,and control non-planned PICU rate,the rate of discharging without medical advice,and mortality,which is worthy of further study and promotion.
2017 Vol. 24 (30): 175-177 [Abstract] ( 153 ) HTML (33 KB)  PDF  (0 KB)  ( 65 )
178 Role of nursing intervention in reducing pain and improving postoperative hip joint mobility in elderly patients with femoral trochanteric fracture
LI Cui-lian;WU Chun-hui; MAI Shao-sheng;YANG Li
ObjectiveTo explore the role of nursing intervention in reducing pain and improving the postoperative hip joint mobility in aged patients with femoral trochanteric fracture.MethodsFrom February 2015 to December 2016,132 patients given the femoral trochanteric fracture treatment in our orthopedics department of our hospital were selected as object.All patients were divided into the experimental group(n＝66)and control group(n＝66)and it was given the nursing intervention and routine nursing.Pain score after intervention and postoperative hip joint mobility and so on between the two groups were compared.ResultsThere was no significant difference of pain score between the two groups after the first day operation(P＞0.05),and after the 7th,14th and 28th operation,the pain score of the experimental group were lower than those of the control group,and there was a statistical difference (P＜0.05).After the 7th operation,there was no statistical difference of hip joint mobility in patients between the two groups(P＞0.05),and after the 30th operation,hip joint mobility in the experimental group was higher than that of the control group,and there was a statistical difference (P＜0.05).After intervention,the total incidence of postoperative adverse reactions in the experimental group was lower than that in the control group,and there was a statistical difference (P＜0.05).The total satisfaction degree of the experimental group after intervention was higher than that of the control group (P＜0.05).ConclusionNursing intervention can reduce the pain of elderly patients with femoral trochanteric fracture,and improve the postoperative hip joint activity,it is worthy of clinical promotion and application.
2017 Vol. 24 (30): 178-180 [Abstract] ( 140 ) HTML (35 KB)  PDF  (0 KB)  ( 65 )
181 Application effect of nursing intervention after painless childbirth
ZHU Xiao-zhen
ObjectiveTo study the application effect of nursing intervention after painless childbirth.MethodsFifty painless childbirth puerperae treated in our hospital from December 2016 to July 2017 were selected as object and they were divided into the control group and observation group,and there were 25 cases in each group.The control group was given the routine nursing,while the observation group was given nursing intervention.The quality of life and psychological status between the two groups were compared.The urination time and occurrence of urinary retention were analyzed.ResultsThe score of quality of life including physical function,psychological function,social function and material life in the observation group were all higher than those in the control group with statistical difference (P＜0.05).The scores of SAS and SDS in the observation group were lower compared with those in the control group.The urination time was shorter and incidence of urinary retention was lower in comparison with those in the control group with statistical differences(P＜0.05).ConclusionNursing intervention applied after painless childbirth for puerperae can improve the quality of puerperae,improve their anxiety nd depression,reduce the incidence of urinary retention.
2017 Vol. 24 (30): 181-182转185 [Abstract] ( 128 ) HTML (28 KB)  PDF  (0 KB)  ( 59 )
183 The role of comprehensive nursing in improving the psychological status,improving the quality of sleep and rehabilitation effect of patients with pulmonary tuberculosis
ZHOU Rui-xia
ObjectiveTo explore the role of comprehensive nursing in improving the psychological status,improving the quality of sleep and rehabilitation effect of patients with pulmonary tuberculosis.Methods96 patients with pulmonary tuberculosis treated in our hospital from December 2015 to December 2016 of were selected as object.Patients were divided into the observation group and control group according to the random number method,and each group had 48 cases.Patients in control group were given the routine nursing,while patients the observation were given comprehensive nursing.The nursing effect,psychological status,sleep quality and rehabilitation effect were compared between the two groups.ResultsAfter nursing,the self-rating anxiety scale (SAS)score,self-rating depression scale (SDS)score and Pittsburgh sleep quality index (PSQI)in the observation group were significantly lower than those in the control group(P＜0.05).The rehabilitation rate of the observation group was significantly higher than that of the control group(P＜0.05).ConclusionCompared with the routine nursing,the role of comprehensive nursing in improving the psychological status of patients with pulmonary tuberculosis,improving the sleep quality and rehabilitation effect is more significant,and it shows a obvious advantages in reducing the negative emotions of anxiety,depression and improving psychological status of patients.It is worthy of clinical promotion and application.
2017 Vol. 24 (30): 183-185 [Abstract] ( 163 ) HTML (30 KB)  PDF  (0 KB)  ( 80 )
186 Application of whole course high-quality nursing during perioperative period of minimally invasive percutaneous nephrolithotomy
LI Chun-ling
ObjectiveTo study the application method and effect of whole course high-quality nursing during perioperative period of minimally invasive percutaneous nephrolithotomy.Methods90 patients with renal calculi underwent minimally invasive percutaneous nephrolithotomy treated in our hospital from February 2015 and February 2017 were selected and they were divided into the observation group (n＝45)and control group (n＝45)according to the random number table method.The control group was given the routine nursing,while the observation group was given whole course high-quality nursing on the basis of the routine nursing.Comfort degree score,visual analogue scale (VAS)score after 12 h and 2 d operation,sleep quality and nursing satisfaction degree in patients between the two groups were compared.ResultsComfort degree score,visual analogue scale (VAS)score after 12 h and 2 d operation,sleep quality and nursing satisfaction degree in patients of the observation group were obviously lower than those of the control group,and there was a statistical difference (P＜0.05).ConclusionMeticulous,professional and humanized whole course high-quality nursing applied in patients with minimally invasive percutaneous nephrolithotomy during perioperative period can meet the emotional needs of patients,reduce the occurrence of postoperative bleeding,improve the clinical effect,and is worthy of clinical promotion and application.
2017 Vol. 24 (30): 186-188 [Abstract] ( 117 ) HTML (30 KB)  PDF  (0 KB)  ( 50 )
189 Application of perioperative high-quality nursing intervention in prevention and treatment of postpartum depression after cesarean section
XIA Lan
ObjectiveTo explore the application effect of perioperative high-quality nursing intervention in prevention and treatment of postpartum depression after cesarean section.MethodsFrom February 2016 to February 2017,126 puerperae undergone cesarean section in our hospital were evenly divided into control group and observation group based on the odd or even sequence of the admission.The patients in the control group were given the routine nursing intervention,while in the observation group,participants were provided with perioperative high-quality nursing intervention.The nursing effect between the two groups was compared.ResultsBefore nursing,there was no significant difference in the score of maternal anxiety and depression between the two groups(P＞0.05).After nursing,the above-mentioned score of puerperae were improved in the two groups,and the scores of anxiety and depression in the observation group were lower in comparison with those in the control group,which were displayed statistical differences(P＜0.05).The total nursing satisfaction degree of the observation group was 96.83%,which was higher than that of the control group (84.13%),and the difference was statistically significant(P＜0.05).ConclusionPerioperative high-quality nursing intervention has a very high application value in the prevention and treatment of postpartum depression after cesarean section.
2017 Vol. 24 (30): 189-191 [Abstract] ( 128 ) HTML (34 KB)  PDF  (0 KB)  ( 64 )
192 Application of clinical nursing pathway in bedside CRRT treatment in patients with severe acute pancreatitis
MA Ren-wei;WANG Ying-yun;DONG Bo
ObjectiveTo explore the application effect of clinical nursing pathway in bedside continuous renal replacement therapy (CRRT)treatment in patients with severe acute pancreatitis.Methods50 patients with severe acute pancreatitis treated in our hospital from February 2014 to December 2016 were selected as object.All patients were treated with bedside CRRT treatment.The patients were divided into the two groups according to the nursing mode,and there were 25 patients in each group.The control group was given the routine nursing,while the study group was given clinical nursing pathway.SAS,SDS score before and after intervention,each dimension score of life quality,nursing satisfaction degree,and the incidence rate of complication between both groups were compared.ResultsSAS and SDS score of patients in the study group were significantly lower than those in the control group (P＜0.05).Each dimension score of life quality in the study group were significantly higher than those in the control group (P＜0.05).The total satisfaction degree in patients of the study group(92.00%)was significantly higher than that of the control group(72.00%)(P＜0.05).The incidence rate of complications in the study group (4.00%)was significantly lower than that in the control group(20%)(P＜0.05).ConclusionThe application of clinical nursing pathway in bedside CRRT treatment of severe acute pancreatitis can significantly improve the anxiety and depression of patients,improve the life quality and nursing satisfaction degree,and reduce the incidence rate of complication.
2017 Vol. 24 (30): 192-194 [Abstract] ( 144 ) HTML (33 KB)  PDF  (0 KB)  ( 67 )
195 Application effect of comfortable nursing in afterloading intracavity radiotherapy for cervical cancer
HUANG Chun-lan;DING Jin-quan;LI Li-hua;WANG Li-ping;LI Jin-xiu
ObjectiveTo investigate the function and effect of comfortable nursing in afterloading intracavity radiotherapy in the patients with cervical cancer.Methods84 patients with cervical cancer who were given afterloading intracavity radiotherapy at the same time of radiotherapy and chemotherapy in the Department of Radiology in our hospital from January 2012 to December 2016 were selected as subjects.According to the admission time,the patients were divided into the control group and the study group,with 42 cases in each group.The control group was hospitalized patients from January 2012 to June 2014 who were given routine care,while the study group was hospitalized patients from July 2014 to December 2016 who were given comfortable care.The satisfaction,vaginal flushing compliance and complications were evaluated and compared between the two groups.ResultsThe patients′satisfaction of the study group (97.62%)was higher than the control group (71.43%),the vaginal flushing compliance was higher than the control group,and the differences were statistically significant(P＜0.05).The patients in the study group had 2 cases of proctitis,1 case of cystitis,while the patients in the control group had 7 cases of vaginal adhesion and stenosis,10 cases of direct enteritis,7 cases of cystitis,and the differences were statistically significant(P＜0.05).ConclusionComfort nursing can improve the treatment initiative and reduce the incidence of complications in the patients with cervical cancer receiving afterloading intracavity radiotherapy,so as to improve the quality of life,which is worthy of clinical promotion.
2017 Vol. 24 (30): 195-197 [Abstract] ( 131 ) HTML (29 KB)  PDF  (0 KB)  ( 39 )
Copyright © Editorial Board of 中国当代医药
Supported by:Beijing Magtech